Page last updated: 2024-08-07 23:54:55
Lipoxygenase
[no definition available]
Synonyms
Research
Bioassay Publications (5)
Timeframe | Studies on this Protein(%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 5 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
masoprocol | Glycine max (soybean) | IC50 | 23.3460 | 5 | 5 |
disufenton sodium | Glycine max (soybean) | IC50 | 57.5000 | 1 | 1 |
New Quinolylnitrones for Stroke Therapy: Antioxidant and Neuroprotective ( Z)- N- tert-Butyl-1-(2-chloro-6-methoxyquinolin-3-yl)methanimine Oxide as a New Lead-Compound for Ischemic Stroke Treatment.Journal of medicinal chemistry, , 02-28, Volume: 62, Issue:4, 2019
Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery.Bioorganic & medicinal chemistry, , 07-30, Volume: 26, Issue:13, 2018
Structural modifications of coumarin derivatives: Determination of antioxidant and lipoxygenase (LOX) inhibitory activity.Bioorganic & medicinal chemistry, , Dec-01, Volume: 22, Issue:23, 2014
Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A₂, cyclooxygenases, lipoxygenase and proinflammatory cytokines.Bioorganic & medicinal chemistry, , Aug-01, Volume: 22, Issue:15, 2014
Novel semicarbazides and ureas of primaquine with bulky aryl or hydroxyalkyl substituents: synthesis, cytostatic and antioxidative activity.European journal of medicinal chemistry, , Oct-30, Volume: 86, 2014