Page last updated: 2024-08-07 19:32:28
Liver carboxylesterase
A protein that is a translation product of the CES1 gene in pig. [PRO:DNx, UniProtKB:Q29550]
Synonyms
EC 3.1.1.1;
Proline-beta-naphthylamidase;
Retinyl ester hydrolase;
REH
Research
Bioassay Publications (8)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
Compounds (6)
Drugs with Inhibition Measurements
Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold.European journal of medicinal chemistry, , Jun-05, Volume: 218, 2021
Synthesis of 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoic acids as new selective carboxylesterase inhibitors and radical scavengers.Bioorganic & medicinal chemistry letters, , 12-01, Volume: 29, Issue:23, 2019
Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease therapeutics.Bioorganic & medicinal chemistry, , 09-01, Volume: 26, Issue:16, 2018
9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment.Bioorganic & medicinal chemistry, , 11-01, Volume: 25, Issue:21, 2017
Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors.Bioorganic & medicinal chemistry, , 08-01, Volume: 25, Issue:15, 2017