glimepiride has been researched along with Sensitivity and Specificity in 13 studies
glimepiride: structure given in first source
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The method was successfully applied in pharmacokinetic studies followed by oral administration of GLM and ILA in rats." | 1.46 | Development of Solid-Phase Extraction and HPLC Method for Simultaneous Estimation of Ilaprazole and Glimepiride in Rat Plasma: Application to Pharmacokinetic Studies. ( Bakal, RL; Chandewar, AV; Dewani, AP; Mohale, DS; Shelke, PG; Tripathi, AS, 2017) |
| " This method was successfully applied to a pharmacokinetic study of coadministeration of BOS and GLP in rats." | 1.43 | Simultaneous Determination of Bosentan, Glimepiride, HYBOS and M1 in Rat Plasma by UPLC-MS-MS and its Application to Pharmacokinetic Study. ( Chen, M; Chen, Q; Hu, G; Pan, P; Song, W; Wang, S; Xu, T; Zheng, Z, 2016) |
| "The rapid, sensitive, and selective liquid chromatography-electrospray ionization-tandem mass spectrometry method (LC-ESI-MS/MS) for the simultaneous estimation and pharmacokinetic investigation of glimepiride and pioglitazone in human plasma has been developed and fully validated." | 1.40 | Simultaneous determination of glimepiride and pioglitazone in human plasma by liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic study. ( Hu, JQ; Ni, XJ; Qiu, C; Shang, DW; Wang, ZZ; Wen, YG; Zhang, M, 2014) |
| "A simple, precise, rapid, and reproducible reversed-phase high-performance liquid chromatography method is developed for the simultaneous estimation of metformin hydrochloride (MET), pioglitazone hydrochloride (PIO), and glimepiride (GLP) present in multicomponent dosage forms." | 1.35 | Simultaneous estimation of metformin hydrochloride, pioglitazone hydrochloride, and glimepiride by RP-HPLC in tablet formulation. ( Amin, M; Jain, D; Jain, S, 2008) |
| " The method was successfully applied to a kinetic study in order to assess the main pharmacokinetic parameters of glimepiride." | 1.33 | Improved liquid chromatographic tandem mass spectrometric determination and pharmacokinetic study of glimepiride in human plasma. ( Koutsopoulou, M; Panderi, I; Pistos, C, 2005) |
| " The proposed method enables the unambiguous identification and quantitation of glimepiride for pharmacokinetic, bioavailability or bioequivalence studies." | 1.32 | Determination of glimepiride in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry. ( Al Tamimi, JI; Idrees, J; Salem, II, 2004) |
| "Glimepiride is a modern hypoglycaemic agent, which belongs to the group of sulfonylurea derivates." | 1.32 | HPLC study of glimepiride under hydrolytic stress conditions. ( Dohnal, J; Klimes, J; Kovaríková, P; Tisovská, L, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ni, XJ | 1 |
| Wang, ZZ | 1 |
| Shang, DW | 1 |
| Zhang, M | 1 |
| Hu, JQ | 1 |
| Qiu, C | 1 |
| Wen, YG | 1 |
| Chen, M | 1 |
| Song, W | 1 |
| Wang, S | 1 |
| Chen, Q | 1 |
| Pan, P | 1 |
| Xu, T | 1 |
| Hu, G | 1 |
| Zheng, Z | 1 |
| Dewani, AP | 1 |
| Tripathi, AS | 1 |
| Shelke, PG | 1 |
| Bakal, RL | 1 |
| Mohale, DS | 1 |
| Chandewar, AV | 1 |
| Surendran, S | 1 |
| Paul, D | 1 |
| Sushmita, R | 1 |
| Krishna, L | 1 |
| Tiwari, NK | 1 |
| Giri, S | 1 |
| Satheeshkumar, N | 1 |
| Jain, D | 2 |
| Jain, S | 1 |
| Amin, M | 1 |
| Kundlik, ML | 1 |
| Zaware, BH | 1 |
| Kuchekar, SR | 1 |
| Park, YS | 1 |
| Kim, SH | 1 |
| Kim, SY | 1 |
| Kim, YH | 1 |
| Lee, MH | 1 |
| Yang, SC | 1 |
| Shaw, LM | 1 |
| Kang, JS | 1 |
| Singh, J | 1 |
| Unnikrishnan, AG | 1 |
| Agrawal, NK | 1 |
| Singh, SK | 1 |
| Agrawal, JK | 1 |
| Salem, II | 1 |
| Idrees, J | 1 |
| Al Tamimi, JI | 1 |
| Kovaríková, P | 1 |
| Klimes, J | 1 |
| Dohnal, J | 1 |
| Tisovská, L | 1 |
| Pistos, C | 1 |
| Koutsopoulou, M | 1 |
| Panderi, I | 1 |
| Chakradhar, L | 1 |
| Kallem, R | 1 |
| Karthik, A | 1 |
| Sundari, BT | 1 |
| Ramesh, S | 1 |
| Mullangi, R | 1 |
| Srinivas, NR | 1 |
| Altinöz, S | 1 |
| Tekeli, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Bioequivalence Study of Two Formulations of Glimepiride Tablet in Healthy Subjects[NCT01677247] | 24 participants (Actual) | Interventional | 2011-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for glimepiride and Sensitivity and Specificity
| Article | Year |
|---|---|
Rapid and specific approach for direct measurement of glimepiride in human plasma by LC-ESI-MS-MS employing automated 96 well format: application to a bioequivalence study.
Topics: Adult; Automation; Chromatography, Liquid; Cross-Over Studies; Drug Stability; Humans; Linear Models | 2012 |
Quantification of galantamine in human plasma by validated liquid chromatography-tandem mass spectrometry using glimepride as an internal standard: application to bioavailability studies in 32 healthy Korean subjects.
Topics: Adult; Biological Availability; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; | 2012 |
11 other studies available for glimepiride and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous determination of glimepiride and pioglitazone in human plasma by liquid chromatography-tandem mass spectrometry and its application to pharmacokinetic study.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Linear Models; Male; Pioglitazone; Reproducibil | 2014 |
Simultaneous Determination of Bosentan, Glimepiride, HYBOS and M1 in Rat Plasma by UPLC-MS-MS and its Application to Pharmacokinetic Study.
Topics: Administration, Oral; Animals; Bosentan; Chromatography, High Pressure Liquid; Hydroxylation; Male; | 2016 |
Development of Solid-Phase Extraction and HPLC Method for Simultaneous Estimation of Ilaprazole and Glimepiride in Rat Plasma: Application to Pharmacokinetic Studies.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Chromatography, High Pressure Liquid; Drug Stabili | 2017 |
A validated LC-MS/MS method for the estimation of glimepiride and pitavastatin in rat plasma: Application to drug interaction studies.
Topics: Animals; Chromatography, Liquid; Drug Interactions; Female; Linear Models; Microsomes, Liver; Quinol | 2017 |
Simultaneous estimation of metformin hydrochloride, pioglitazone hydrochloride, and glimepiride by RP-HPLC in tablet formulation.
Topics: Chromatography, High Pressure Liquid; Hypoglycemic Agents; Metformin; Pioglitazone; Reference Standa | 2008 |
Immunoreactive insulin response to a single dose of glimepiride in lean type 2 diabetic subjects.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; | 2002 |
Determination of glimepiride in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Humans; Hypoglycemic Agents; Reproducibility of Results; Sensi | 2004 |
HPLC study of glimepiride under hydrolytic stress conditions.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Hydrolysis; Oxidation-Reduction; Reference Sta | 2004 |
Improved liquid chromatographic tandem mass spectrometric determination and pharmacokinetic study of glimepiride in human plasma.
Topics: Chromatography, High Pressure Liquid; Female; Humans; Hypoglycemic Agents; Male; Mass Spectrometry; | 2005 |
A rapid and highly sensitive method for the determination of glimepiride in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a pre-clinical pharmacokinetic study.
Topics: Acetates; Acetonitriles; Administration, Oral; Animals; Chemical Fractionation; Chromatography, High | 2008 |
Analysis of glimepiride by using derivative UV spectrophotometric method.
Topics: Drug Stability; Hypoglycemic Agents; Reproducibility of Results; Sensitivity and Specificity; Spectr | 2001 |