Proteins > 5-hydroxytryptamine receptor 7
Page last updated: 2024-08-07 13:20:42
5-hydroxytryptamine receptor 7
A protein that is a translation product of the HTR7 gene in guinea pig. [PRO:DNx, UniProtKB:P50407]
Synonyms
5-HT-7;
5-HT7;
5-HT-X;
Serotonin receptor 7
Research
Bioassay Publications (5)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (52)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| oxamic acid | Cavia porcellus (domestic guinea pig) | IC50 | 1,237.0000 | 2 | 5 |
| 8-hydroxy-2-(di-n-propylamino)tetralin | Cavia porcellus (domestic guinea pig) | Ki | 0.0021 | 1 | 2 |
| 5-carboxamidotryptamine | Cavia porcellus (domestic guinea pig) | Ki | 0.0005 | 1 | 1 |
| amitriptyline | Cavia porcellus (domestic guinea pig) | IC50 | 16.9000 | 1 | 2 |
| amsacrine | Cavia porcellus (domestic guinea pig) | IC50 | 5.0000 | 1 | 2 |
| verapamil | Cavia porcellus (domestic guinea pig) | IC50 | 6.8000 | 1 | 2 |
| chlorpromazine | Cavia porcellus (domestic guinea pig) | IC50 | 27.0000 | 1 | 2 |
| citalopram | Cavia porcellus (domestic guinea pig) | IC50 | 18.8000 | 1 | 2 |
| clomipramine | Cavia porcellus (domestic guinea pig) | IC50 | 19.3000 | 1 | 2 |
| clonidine | Cavia porcellus (domestic guinea pig) | IC50 | 22.6000 | 1 | 2 |
| desipramine | Cavia porcellus (domestic guinea pig) | IC50 | 56.8000 | 1 | 2 |
| disopyramide | Cavia porcellus (domestic guinea pig) | IC50 | 81.7000 | 1 | 2 |
| fluphenazine | Cavia porcellus (domestic guinea pig) | IC50 | 110.0000 | 1 | 2 |
| gossypol | Cavia porcellus (domestic guinea pig) | IC50 | 2.2740 | 2 | 5 |
| haloperidol | Cavia porcellus (domestic guinea pig) | IC50 | 141.9000 | 1 | 2 |
| imipramine | Cavia porcellus (domestic guinea pig) | IC50 | 17.1000 | 1 | 2 |
| ketanserin | Cavia porcellus (domestic guinea pig) | Ki | 0.0035 | 1 | 1 |
| loperamide | Cavia porcellus (domestic guinea pig) | IC50 | 23.7000 | 1 | 2 |
| memantine | Cavia porcellus (domestic guinea pig) | IC50 | 27.2000 | 1 | 2 |
| metoclopramide | Cavia porcellus (domestic guinea pig) | IC50 | 94.8000 | 1 | 2 |
| ondansetron | Cavia porcellus (domestic guinea pig) | IC50 | 20.4000 | 1 | 2 |
| orphenadrine | Cavia porcellus (domestic guinea pig) | IC50 | 12.6000 | 1 | 2 |
| oxprenolol | Cavia porcellus (domestic guinea pig) | IC50 | 28.6000 | 1 | 2 |
| phenoxybenzamine | Cavia porcellus (domestic guinea pig) | IC50 | 15.1000 | 1 | 2 |
| prazosin | Cavia porcellus (domestic guinea pig) | IC50 | 9.9000 | 1 | 2 |
| prochlorperazine | Cavia porcellus (domestic guinea pig) | IC50 | 49.6000 | 1 | 2 |
| promazine | Cavia porcellus (domestic guinea pig) | IC50 | 17.2000 | 1 | 2 |
| promethazine | Cavia porcellus (domestic guinea pig) | IC50 | 35.1000 | 1 | 2 |
| propafenone | Cavia porcellus (domestic guinea pig) | IC50 | 11.1000 | 1 | 2 |
| propranolol | Cavia porcellus (domestic guinea pig) | IC50 | 63.2000 | 1 | 2 |
| terazosin | Cavia porcellus (domestic guinea pig) | IC50 | 23.7000 | 1 | 2 |
| ultram | Cavia porcellus (domestic guinea pig) | IC50 | 52.5000 | 1 | 2 |
| trimethoprim | Cavia porcellus (domestic guinea pig) | IC50 | 56.8000 | 1 | 2 |
| trimipramine | Cavia porcellus (domestic guinea pig) | IC50 | 27.7000 | 1 | 2 |
| apomorphine | Cavia porcellus (domestic guinea pig) | IC50 | 20.8000 | 1 | 2 |
| mepenzolate bromide | Cavia porcellus (domestic guinea pig) | IC50 | 64.9000 | 1 | 2 |
| nandrolone | Cavia porcellus (domestic guinea pig) | IC50 | 35.1000 | 1 | 2 |
| amiloride | Cavia porcellus (domestic guinea pig) | IC50 | 57.0000 | 1 | 2 |
| clemastine | Cavia porcellus (domestic guinea pig) | IC50 | 4.9000 | 1 | 2 |
| diltiazem | Cavia porcellus (domestic guinea pig) | IC50 | 12.4000 | 1 | 2 |
| bucindolol | Cavia porcellus (domestic guinea pig) | IC50 | 27.2000 | 1 | 2 |
| repaglinide | Cavia porcellus (domestic guinea pig) | IC50 | 9.2000 | 1 | 2 |
| atropine | Cavia porcellus (domestic guinea pig) | IC50 | 12.2000 | 1 | 2 |
| quinidine | Cavia porcellus (domestic guinea pig) | IC50 | 113.8000 | 1 | 2 |
| chlorprothixene | Cavia porcellus (domestic guinea pig) | IC50 | 77.8000 | 1 | 2 |
| quinine | Cavia porcellus (domestic guinea pig) | IC50 | 51.6000 | 1 | 2 |
| flupenthixol | Cavia porcellus (domestic guinea pig) | IC50 | 89.5000 | 1 | 4 |
| morphine | Cavia porcellus (domestic guinea pig) | IC50 | 28.0000 | 1 | 2 |
| denopamine | Cavia porcellus (domestic guinea pig) | IC50 | 46.9000 | 1 | 2 |
| n-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide | Cavia porcellus (domestic guinea pig) | Ki | 0.0006 | 1 | 1 |
Drugs with Activation Measurements
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| tetraethylammonium | Cavia porcellus (domestic guinea pig) | Km | 2.3200 | 1 | 2 |