| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Encephalitis, Polio
[description not available] | 0 | 2.06 | 1 | 0 |
Poliomyelitis
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5) | 0 | 2.06 | 1 | 0 |
Hepatocellular Carcinoma
[description not available] | 0 | 11.01 | 5 | 2 |
Cancer of Liver
[description not available] | 0 | 8.02 | 10 | 2 |
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 6.01 | 5 | 2 |
Liver Neoplasms
Tumors or cancer of the LIVER. | 0 | 8.02 | 10 | 2 |
Chronic Liver Failure
[description not available] | 0 | 4 | 4 | 0 |
End Stage Liver Disease
Final stage of a liver disease when the liver failure is irreversible and LIVER TRANSPLANTATION is needed. | 0 | 4 | 4 | 0 |
Overweight
A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat. | 0 | 2.51 | 2 | 0 |
Fatty Liver, Nonalcoholic
[description not available] | 0 | 3.36 | 5 | 0 |
Diabetes Mellitus, Adult-Onset
[description not available] | 0 | 2.6 | 1 | 0 |
Cirrhosis, Liver
[description not available] | 0 | 13.01 | 62 | 11 |
Diabetes Mellitus, Type 2
A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. | 0 | 2.6 | 1 | 0 |
Liver Cirrhosis
Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. | 0 | 13.01 | 62 | 11 |
Obesity
A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 9.62 | 5 | 1 |
Non-alcoholic Fatty Liver Disease
Fatty liver finding without excessive ALCOHOL CONSUMPTION. | 0 | 3.36 | 5 | 0 |
Asystole
[description not available] | 0 | 2.25 | 1 | 0 |
Heart Arrest
Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation. | 0 | 2.25 | 1 | 0 |
Liver Dysfunction
[description not available] | 0 | 9.26 | 17 | 1 |
Liver Diseases
Pathological processes of the LIVER. | 0 | 9.26 | 17 | 1 |
Acute Liver Injury, Drug-Induced
[description not available] | 0 | 3.71 | 3 | 0 |
Liver Steatosis
[description not available] | 0 | 4.55 | 5 | 1 |
Colorectal Cancer
[description not available] | 0 | 2.15 | 1 | 0 |
Fatty Liver
Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS. | 0 | 9.55 | 5 | 1 |
Colorectal Neoplasms
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. | 0 | 2.15 | 1 | 0 |
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 3.71 | 3 | 0 |
Disease Exacerbation
[description not available] | 0 | 4.15 | 5 | 0 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 2.76 | 3 | 0 |
Anorexia Nervosa
An eating disorder that is characterized by the lack or loss of APPETITE, known as ANOREXIA. Other features include excess fear of becoming OVERWEIGHT; BODY IMAGE disturbance; significant WEIGHT LOSS; refusal to maintain minimal normal weight; and AMENORRHEA. This disorder occurs most frequently in adolescent females. (APA, Thesaurus of Psychological Index Terms, 1994) | 0 | 2.17 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2.77 | 3 | 0 |
Complication, Postoperative
[description not available] | 0 | 4.65 | 3 | 0 |
Hepatic Failure
[description not available] | 0 | 4.09 | 5 | 0 |
Postoperative Complications
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. | 0 | 4.65 | 3 | 0 |
Liver Failure
Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed) | 0 | 4.09 | 5 | 0 |
Biliary Cirrhosis
[description not available] | 0 | 4.37 | 4 | 1 |
Liver Cirrhosis, Biliary
FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes. | 0 | 4.37 | 4 | 1 |
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 13.53 | 36 | 10 |
Chronic Hepatitis C
[description not available] | 0 | 9.42 | 24 | 1 |
Hepatitis C, Chronic
INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS. | 0 | 9.42 | 24 | 1 |
Blood Pressure, High
[description not available] | 0 | 3.48 | 1 | 1 |
Hypertension
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 3.48 | 1 | 1 |
Ascites
Accumulation or retention of free fluid within the peritoneal cavity. | 0 | 3.03 | 1 | 0 |
Cirrhosis
[description not available] | 0 | 3.06 | 1 | 0 |
Fibrosis
Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. | 0 | 3.06 | 1 | 0 |
Innate Inflammatory Response
[description not available] | 0 | 2.96 | 1 | 0 |
Inflammation
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 7.96 | 1 | 0 |
Weight Gain
Increase in BODY WEIGHT over existing weight. | 0 | 2.46 | 2 | 0 |
Mushroom Poisoning
Poisoning from ingestion of mushrooms, primarily from, but not restricted to, toxic varieties. | 0 | 2.04 | 1 | 0 |
Choline Deficiency
A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984) | 0 | 2.04 | 1 | 0 |
Acute Hepatic Failure
[description not available] | 0 | 2.04 | 1 | 0 |
Liver Failure, Acute
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C. | 0 | 2.04 | 1 | 0 |
Hepatitis B Virus Infection
[description not available] | 0 | 4.35 | 1 | 1 |
Cerebral Pseudosclerosis
[description not available] | 0 | 4.35 | 1 | 1 |
Complications, Pregnancy
[description not available] | 0 | 4.35 | 1 | 1 |
Acute Disease
Disease having a short and relatively severe course. | 0 | 4.76 | 2 | 1 |
Hepatitis
INFLAMMATION of the LIVER. | 0 | 4.7 | 2 | 1 |
Hepatitis B
INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact. | 0 | 4.35 | 1 | 1 |
Hepatolenticular Degeneration
A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years. | 0 | 4.35 | 1 | 1 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 6.17 | 5 | 1 |
Cardiac Failure
[description not available] | 0 | 2.05 | 1 | 0 |
Heart Failure
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. | 0 | 7.05 | 1 | 0 |
Bile Duct Obstruction, Extrahepatic
[description not available] | 0 | 2.05 | 1 | 0 |
Cirrhoses, Experimental Liver
[description not available] | 0 | 2.05 | 1 | 0 |
Chronic Hepatitis B
[description not available] | 0 | 2.06 | 1 | 0 |
Hepatitis B, Chronic
INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact. | 0 | 2.06 | 1 | 0 |
Chronic Hepatitis
[description not available] | 0 | 9.81 | 11 | 9 |
Hepatitis, Chronic
INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors. | 0 | 9.81 | 11 | 9 |
Atresia, Biliary
[description not available] | 0 | 3.87 | 2 | 1 |
Bile Duct Obstruction
[description not available] | 0 | 3.87 | 2 | 1 |
Biliary Atresia
Progressive destruction or the absence of all or part of the extrahepatic BILE DUCTS, resulting in the complete obstruction of BILE flow. Usually, biliary atresia is found in infants and accounts for one third of the neonatal cholestatic JAUNDICE. | 0 | 8.87 | 2 | 1 |
Cholestasis
Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS). | 0 | 8.87 | 2 | 1 |
Anoxemia
[description not available] | 0 | 2.01 | 1 | 0 |
Hypoxia
Sub-optimal OXYGEN levels in the ambient air of living organisms. | 0 | 2.01 | 1 | 0 |
Cholera Infantum
[description not available] | 0 | 1.96 | 1 | 0 |
Fetal Growth Restriction
[description not available] | 0 | 2.67 | 3 | 0 |
Fetal Growth Retardation
Failure of a FETUS to attain expected GROWTH. | 0 | 2.67 | 3 | 0 |
Infant, Small for Gestational Age
An infant having a birth weight lower than expected for its gestational age. | 0 | 3.59 | 3 | 0 |
Viral Hepatitis, Human
[description not available] | 0 | 2.91 | 1 | 0 |
Hepatitis, Viral, Human
INFLAMMATION of the LIVER in humans due to infection by VIRUSES. There are several significant types of human viral hepatitis with infection caused by enteric-transmission (HEPATITIS A; HEPATITIS E) or blood transfusion (HEPATITIS B; HEPATITIS C; and HEPATITIS D). | 0 | 2.91 | 1 | 0 |
Alcoholic Cirrhosis
[description not available] | 0 | 1.99 | 1 | 0 |
Liver Cirrhosis, Alcoholic
FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING. | 0 | 1.99 | 1 | 0 |
Chronic Illness
[description not available] | 0 | 2.92 | 1 | 0 |
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 2.92 | 1 | 0 |
Eczema, Atopic
[description not available] | 0 | 1.98 | 1 | 0 |
Allergy, Food
[description not available] | 0 | 1.98 | 1 | 0 |
Dermatitis, Atopic
A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema. | 0 | 1.98 | 1 | 0 |
Food Hypersensitivity
Gastrointestinal disturbances, skin eruptions, or shock due to allergic reactions to allergens in food. | 0 | 1.98 | 1 | 0 |
Infant, Premature, Diseases
Diseases that occur in PREMATURE INFANTS. | 0 | 1.97 | 1 | 0 |
Blood Poisoning
[description not available] | 0 | 1.97 | 1 | 0 |
Sepsis
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | 0 | 1.97 | 1 | 0 |
Encephalopathy, Hepatic
[description not available] | 0 | 1.97 | 1 | 0 |
Hepatic Encephalopathy
A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5) | 0 | 1.97 | 1 | 0 |
Alcoholic Liver Diseases
[description not available] | 0 | 1.97 | 1 | 0 |
Liver Diseases, Alcoholic
Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS. | 0 | 1.97 | 1 | 0 |