Trehalase

A trehalase that is encoded in the genome of human. [PRO:DNx, UniProtKB:O43280]

EC 3.2.1.28;
Alpha,alpha-trehalase;
Alpha,alpha-trehalose glucohydrolase

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
1-deoxynojirimycin	Homo sapiens (human)	IC50	40.0000	1	1

This protein enables 1 target(s):

Target	Category	Definition
alpha,alpha-trehalase activity	molecular function	Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose. [PMID:19897915, RHEA:32675]

This protein is located in 4 target(s):

Target	Category	Definition
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
membrane	cellular component	A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
extracellular exosome	cellular component	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]
side of membrane	cellular component	A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface. [GOC:dos]

This protein is involved in 3 target(s):

Target	Category	Definition
trehalose metabolic process	biological process	The chemical reactions and pathways involving trehalose, a disaccharide that consists of two molecules of glucose and is isomeric with sucrose. [GOC:jl, ISBN:0028623819]
trehalose catabolic process	biological process	The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide that consists of two molecules of glucose and is isomeric with sucrose. [GOC:jl, ISBN:0028623819]
animal organ morphogenesis	biological process	Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544]