lidocaine has been researched along with Sensitivity and Specificity in 139 studies
Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.
lidocaine : The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A fast liquid chromatography-tandem mass spectrometry with electrospray ionization method was developed and validated for simultaneous quantification of lidocaine and its active metabolite MEGX in 10 μL of plasma of neonates with seizures." | 7.78 | Easy and fast LC-MS/MS determination of lidocaine and MEGX in plasma for therapeutic drug monitoring in neonates with seizures. ( ter Weijden, E; van den Broek, MP; Ververs, FF, 2012) |
| "The prognostic value of a dynamic liver-function test, based on the hepatic conversion of lidocaine to monoethylglycinexylidide (MEGX), in predicting multiple organ failure (MOF) was prospectively investigated in 28 critically ill patients after multiple trauma." | 7.69 | Monoethylglycinexylidide as an early predictor of posttraumatic multiple organ failure. ( Armstrong, VW; Lehmann, U; Oellerich, M; Pape, D; Regel, G; Schütz, E, 1995) |
| "Hypotension is a common side effect associated with spinal anesthesia." | 6.70 | Hypotension in spinal anesthesia for cesarean section: a comparison of 0.5% hyperbaric bupivacaine and 5% hyperbaric lidocaine. ( Charuluxananan, S; Kyokong, O; Leerapun, R; Pothimamaka, S, 2001) |
| " After oral lidocaine, cirrhotic patients has a longer time to peak concentration (Tmax) and elimination half-life (t1/2), and a higher area under the curve (AUC)." | 6.68 | Pharmacokinetics of oral lidocaine and nifedipine in patients with liver cirrhosis. ( Klangwarnwong, D; Manorot, M; Praisontarangkul, OA; Tonsuwannont, W, 1996) |
| "Both lidocaine an adrenaline at the scheduled doses showed low sensitivity and specificity as a simulated iv epidural test dose." | 5.20 | [Epidural anaesthesia: Simulated intravascular test dose with S(+) ketamine, lidocaine and adrenaline. A prospective, randomized, double blind and placebo controlled study]. ( Errando, CL; Higueras, R; Soriano-Bru, JL, 2015) |
| " To compare local anesthesia (1% lidocaine) with forced coughing as pain relief, we quantified the actual pain experienced during cervical punch biopsies." | 5.13 | Forced coughing versus local anesthesia and pain associated with cervical biopsy: a randomized trial. ( Hefler, L; Heinze, G; Pils, S; Reinthaller, A; Schmid, BC; Speiser, P, 2008) |
| "General anesthesia via laryngeal mask airway or lidocaine subarachnoid block anesthesia for inguinal hernia repair." | 5.11 | Comparison of spinal vs general anesthesia via laryngeal mask airway in inguinal hernia repair. ( Burney, RE; Greenfield, ML; O'Reilly, M; Prabhu, MA; Shanks, A, 2004) |
| "Intravenous cannulation in children aged 6-12 years is less painful after a 90-min application of a Lidocaine/ Prilocaine cream followed by a 30-min interval without cream, than cannulation immediately after a 60-min application." | 5.11 | Improved application of Lidocaine/Prilocaine cream in children. A randomized and prospectively controlled study of two application regimes. ( Culmsee, M; Gad, LN; Lysgaard, AB; Olsen, KS, 2004) |
| "A fast liquid chromatography-tandem mass spectrometry with electrospray ionization method was developed and validated for simultaneous quantification of lidocaine and its active metabolite MEGX in 10 μL of plasma of neonates with seizures." | 3.78 | Easy and fast LC-MS/MS determination of lidocaine and MEGX in plasma for therapeutic drug monitoring in neonates with seizures. ( ter Weijden, E; van den Broek, MP; Ververs, FF, 2012) |
| "Hyperbilirubinemia, which frequently occurs in severe liver disease, interferes with the fluorescence polarization immunoassay (FPIA) monoethylglycinexylidide (MEGX) assay manufactured by Abbott Diagnostics." | 3.70 | Determination of monoethylglycinexylidide by fluorescence polarization immunoassay in highly icteric serum samples: modified precipitation procedure and HPLC compared. ( Armstrong, VW; Niedmann, PD; Oellerich, M; Schütz, E; Shipkova, M; Wieland, E, 1998) |
| "The prognostic value of a dynamic liver-function test, based on the hepatic conversion of lidocaine to monoethylglycinexylidide (MEGX), in predicting multiple organ failure (MOF) was prospectively investigated in 28 critically ill patients after multiple trauma." | 3.69 | Monoethylglycinexylidide as an early predictor of posttraumatic multiple organ failure. ( Armstrong, VW; Lehmann, U; Oellerich, M; Pape, D; Regel, G; Schütz, E, 1995) |
| "Early repair of rotator cuff tears leads to superior results." | 2.75 | The value of clinical tests in acute full-thickness tears of the supraspinatus tendon: does a subacromial lidocaine injection help in the clinical diagnosis? A prospective study. ( Bak, K; Jørgensen, U; Krarup, AL; Nygaard, M; Pedersen, ST; Sloth, C; Sørensen, AK; Thune, C, 2010) |
| "Pilsicainide and bepridil were effective in 19 and 20 patients, respectively." | 2.74 | Predicting the efficacy of antiarrhythmic agents for interrupting persistent atrial fibrillation according to spectral analysis of the fibrillation waves on the surface ECG. ( Fujiki, A; Fukaya, H; Hatakeyama, Y; Izumi, T; Kiryu, M; Kurokawa, S; Niwano, H; Niwano, S; Sasaki, T, 2009) |
| "Hypotension is a common side effect associated with spinal anesthesia." | 2.70 | Hypotension in spinal anesthesia for cesarean section: a comparison of 0.5% hyperbaric bupivacaine and 5% hyperbaric lidocaine. ( Charuluxananan, S; Kyokong, O; Leerapun, R; Pothimamaka, S, 2001) |
| "An accurate assessment of the risk of a bladder cancer can be obtained with NMP22, cytology, and cystoscopy in patients with a history of bladder cancer." | 2.69 | Clinical application of NMP22 in the management of transitional cell carcinoma of the bladder. ( Bagiella, E; Sawczuk, AT; Sawczuk, IS; Yun, EJ, 2000) |
| "Bilirubin values were elevated in the non-survivor group (median: 2." | 2.68 | Lignocaine metabolite formation: an indicator for liver dysfunction and predictor of survival in surgical intensive care patients. ( Böhrer, H; Böttiger, BW; Martin, E; Schmidt, H; Schröter, J; Wandel, C, 1995) |
| " After oral lidocaine, cirrhotic patients has a longer time to peak concentration (Tmax) and elimination half-life (t1/2), and a higher area under the curve (AUC)." | 2.68 | Pharmacokinetics of oral lidocaine and nifedipine in patients with liver cirrhosis. ( Klangwarnwong, D; Manorot, M; Praisontarangkul, OA; Tonsuwannont, W, 1996) |
| " The methods allowed local measurement of lidocaine in stratum corneum, punch biopsies, and plasma and of 2,6-DMA in plasma and biopsies obtained from minipigs dosed with experimental transdermal formulations." | 1.48 | Measurement of lidocaine and 2,6-dimethylaniline in minipig plasma, skin, and dermal tapes using UHPLC with electrospray MS/MS. ( Bakhtiar, R; Engel, BJ; Green, C; King, B; Li, Q; Magers, T; Shoup, R, 2018) |
| "Surgical site infections are common, with an incidence of 1." | 1.38 | Effect of local anesthetic on microorganisms in a murine model of surgical site infection. ( Barlow, P; Bemis, D; Coan, P; Daley, BJ; Goldman, MH; Karlstad, M; Lawson, CM; Newkirk, K; Norwood, J; Sams, VG, 2012) |
| " Also there was achieved a parallel analysis of buthylhydroxyanisol, as a preservative, and hydroquinone, as a degradation product of calcium dobesilate, present in these dosage forms." | 1.33 | Validation of liquid chromatographic method for analysis of lidocaine hydrochloride, dexamethasone acetate, calcium dobesilate, buthylhydroxyanisol and degradation product hydroquinone in suppositories and ointment. ( Ivanovic, I; Markovic, S; Petrovic, S; Zecevic, M; Zivanovic, Lj, 2005) |
| "Lidocaine and phenol were injected into the sciatic nerves of the rats in Groups 1 and 2, respectively." | 1.32 | Free radical-induced damage in experimental peripheral nerve injection injury. ( Apan, A; Kisa, U; Saray, A, 2003) |
| "LPS-induced hypotension has been attributed to nitric oxide (NO) activation of leukocytes, oxidants, cytokines, and other causes." | 1.31 | A role for abdominal vagal afferents in lipopolysaccharide-induced hypotension. ( Mailman, D, 2002) |
| "The purpose of our study was to develop a physiologically based pharmacokinetic (PBPK) model describing the behavior of lidocaine in humans by scaling up physiological variables from animal models of cardiac arrest." | 1.31 | Prediction of lidocaine tissue concentrations following different dose regimes during cardiac arrest using a physiologically based pharmacokinetic model. ( Grillo, JA; Ornato, JP; Venitz, J, 2001) |
| "Sensitivity and specificity were 50% and 97%, respectively." | 1.29 | Factors associated with hypotension and bradycardia after epidural blockade. ( Curatolo, M; Orlando, A; Scaramozzino, P; Venuti, FS; Zbinden, AM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 53 (38.13) | 18.2507 |
| 2000's | 62 (44.60) | 29.6817 |
| 2010's | 22 (15.83) | 24.3611 |
| 2020's | 2 (1.44) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, BY | 1 |
| Toyama, BH | 1 |
| Wille, H | 1 |
| Colby, DW | 1 |
| Collins, SR | 1 |
| May, BC | 1 |
| Prusiner, SB | 1 |
| Weissman, J | 1 |
| Shoichet, BK | 1 |
| Li, H | 1 |
| Sun, J | 1 |
| Sui, X | 1 |
| Liu, J | 1 |
| Yan, Z | 1 |
| Liu, X | 1 |
| Sun, Y | 1 |
| He, Z | 1 |
| Kesici, S | 1 |
| Demirci, M | 1 |
| Kesici, U | 1 |
| Pysarevska, S | 1 |
| Plotycya, S | 1 |
| Dubenska, L | 1 |
| Gao, G | 1 |
| Fu, Q | 2 |
| Wu, R | 1 |
| Liu, R | 1 |
| Cui, L | 1 |
| Xu, Y | 1 |
| Yan, Q | 1 |
| An, HY | 1 |
| Feng, Y | 1 |
| Makdisi, JR | 1 |
| Kim, DP | 1 |
| Klein, PA | 1 |
| Klein, JA | 1 |
| Li, Q | 1 |
| Magers, T | 1 |
| King, B | 1 |
| Engel, BJ | 1 |
| Bakhtiar, R | 1 |
| Green, C | 1 |
| Shoup, R | 1 |
| Nie, H | 1 |
| Kubrova, E | 1 |
| Wu, T | 1 |
| Denbeigh, JM | 1 |
| Hunt, C | 1 |
| Dietz, AB | 1 |
| Smith, J | 1 |
| Qu, W | 1 |
| van Wijnen, AJ | 1 |
| Cuneo, BF | 1 |
| Strasburger, JF | 1 |
| Yu, S | 1 |
| Horigome, H | 1 |
| Hosono, T | 1 |
| Kandori, A | 1 |
| Wakai, RT | 1 |
| Dołowy, M | 1 |
| Kulpińska-Kucia, K | 1 |
| Pyka, A | 1 |
| Higueras, R | 1 |
| Errando, CL | 1 |
| Soriano-Bru, JL | 1 |
| Arnhard, K | 1 |
| Gottschall, A | 1 |
| Pitterl, F | 1 |
| Oberacher, H | 1 |
| Shimizu, M | 1 |
| Hashiguchi, M | 1 |
| Shiga, T | 1 |
| Nakamura, K | 1 |
| Tamura, HO | 1 |
| Mochizuki, M | 1 |
| Abdelwahab, NS | 1 |
| Ali, NW | 1 |
| Abdelkawy, M | 1 |
| Emam, AA | 1 |
| del Mar LópezGuerrero, M | 1 |
| Hernández-Mesa, M | 1 |
| Cruces-Blanco, C | 1 |
| García-Campaña, AM | 1 |
| Kaweski, S | 1 |
| Schmid, BC | 1 |
| Pils, S | 1 |
| Heinze, G | 1 |
| Hefler, L | 1 |
| Reinthaller, A | 1 |
| Speiser, P | 1 |
| Pershad, J | 1 |
| Steinberg, SC | 1 |
| Waters, TM | 1 |
| Aydin, U | 1 |
| Rehimli, M | 1 |
| Kahveci, R | 1 |
| McKenna, C | 1 |
| Bojke, L | 1 |
| Manca, A | 1 |
| Adebajo, A | 1 |
| Dickson, J | 1 |
| Helliwell, P | 1 |
| Morton, V | 1 |
| Russell, I | 1 |
| Torgerson, D | 1 |
| Watson, J | 1 |
| Foster, DC | 1 |
| Beth Kotok, M | 1 |
| Huang, LS | 1 |
| Watts, A | 1 |
| Oakes, D | 1 |
| Howard, FM | 1 |
| Stodgell, CJ | 1 |
| Dworkin, RH | 1 |
| Niwano, S | 1 |
| Sasaki, T | 1 |
| Kurokawa, S | 1 |
| Kiryu, M | 1 |
| Fukaya, H | 1 |
| Hatakeyama, Y | 1 |
| Niwano, H | 1 |
| Fujiki, A | 1 |
| Izumi, T | 1 |
| Shimeno, K | 1 |
| Takagi, M | 1 |
| Maeda, K | 1 |
| Tatsumi, H | 1 |
| Doi, A | 1 |
| Nakagawa, E | 1 |
| Yoshiyama, M | 1 |
| Qin, WW | 1 |
| Jiao, Z | 1 |
| Zhong, MK | 1 |
| Shi, XJ | 1 |
| Zhang, J | 1 |
| Li, ZD | 1 |
| Cui, XY | 1 |
| Bak, K | 1 |
| Sørensen, AK | 1 |
| Jørgensen, U | 1 |
| Nygaard, M | 1 |
| Krarup, AL | 1 |
| Thune, C | 1 |
| Sloth, C | 1 |
| Pedersen, ST | 1 |
| Pendela, M | 1 |
| Kahsay, G | 1 |
| Baekelandt, I | 1 |
| Van Schepdael, A | 1 |
| Adams, E | 1 |
| Chu, B | 1 |
| Lou, D | 1 |
| Yu, P | 1 |
| Hu, S | 1 |
| Shen, S | 1 |
| Donovan, L | 1 |
| Selkow, NM | 1 |
| Rupp, K | 1 |
| Saliba, E | 1 |
| Saliba, S | 1 |
| Murata, K | 1 |
| Ueyama, T | 1 |
| Tanaka, T | 1 |
| Nose, Y | 1 |
| Wada, Y | 1 |
| Matsuzaki, M | 1 |
| ter Weijden, E | 1 |
| van den Broek, MP | 1 |
| Ververs, FF | 1 |
| Goineau, S | 1 |
| Castagné, V | 1 |
| Guillaume, P | 1 |
| Froget, G | 1 |
| Sams, VG | 1 |
| Lawson, CM | 1 |
| Coan, P | 1 |
| Bemis, D | 1 |
| Newkirk, K | 1 |
| Karlstad, M | 1 |
| Norwood, J | 1 |
| Barlow, P | 1 |
| Goldman, MH | 1 |
| Daley, BJ | 1 |
| Vastani, N | 1 |
| Seifert, B | 1 |
| Spahn, DR | 1 |
| Maurer, K | 1 |
| Mailman, D | 1 |
| Purali, N | 1 |
| Henry, BJ | 1 |
| Kenison, M | 1 |
| McVay, C | 1 |
| Rolfe, R | 1 |
| Graham, S | 1 |
| Rasty, J | 1 |
| Slauterbeck, J | 1 |
| Dabezies, EJ | 1 |
| Jing, M | 1 |
| Wu, G | 1 |
| Yang, D | 1 |
| Golpe Gómez, R | 1 |
| Mateos Colino, A | 1 |
| Yamamoto, LG | 1 |
| Nomura, JT | 1 |
| Sato, RL | 1 |
| Ahern, RM | 1 |
| Snow, JL | 1 |
| Kuwaye, TT | 1 |
| Ogasawara, K | 1 |
| Tanaka, M | 4 |
| Nishikawa, T | 2 |
| Saray, A | 1 |
| Apan, A | 1 |
| Kisa, U | 1 |
| Horiuchi, A | 1 |
| Nakayama, Y | 1 |
| Gaiser, RR | 1 |
| Burney, RE | 1 |
| Prabhu, MA | 1 |
| Greenfield, ML | 1 |
| Shanks, A | 1 |
| O'Reilly, M | 1 |
| Gad, LN | 1 |
| Olsen, KS | 1 |
| Lysgaard, AB | 1 |
| Culmsee, M | 1 |
| Walton, J | 1 |
| Mahajan, S | 1 |
| Paxinos, A | 1 |
| Marshall, J | 1 |
| Bryant, C | 1 |
| Shnier, R | 1 |
| Quinn, R | 1 |
| Murrell, GA | 1 |
| Piwowarska, J | 1 |
| Kuczyñska, J | 1 |
| Pachecka, J | 1 |
| Neto, HS | 1 |
| Pertille, A | 1 |
| Teodori, RM | 1 |
| Somazz, MC | 1 |
| Marques, MJ | 1 |
| Al-Rawi, PG | 1 |
| Sigaudo-Roussel, D | 1 |
| Gaunt, ME | 1 |
| Niimi, Y | 1 |
| Sala, F | 1 |
| Deletis, V | 1 |
| Setton, A | 1 |
| de Camargo, AB | 1 |
| Berenstein, A | 1 |
| Anderson, MS | 1 |
| Lu, B | 1 |
| Abdel-Rehim, M | 2 |
| Blomberg, S | 1 |
| Blomberg, LG | 1 |
| Oztürk, E | 1 |
| Möhür, H | 1 |
| Arslan, N | 1 |
| Entok, E | 1 |
| Tan, K | 1 |
| Ozgüven, MA | 1 |
| Bagonluri, MT | 1 |
| Woodbury, MR | 1 |
| Reid, RS | 1 |
| Boison, JO | 1 |
| Wei, ZW | 1 |
| Yun, KM | 1 |
| Zhang, N | 1 |
| Zivanovic, Lj | 1 |
| Zecevic, M | 1 |
| Markovic, S | 1 |
| Petrovic, S | 1 |
| Ivanovic, I | 1 |
| Redolfi, S | 1 |
| Raux, M | 1 |
| Donzel-Raynaud, C | 1 |
| Morelot-Panzini, C | 1 |
| Zelter, M | 1 |
| Derenne, JP | 1 |
| Similowski, T | 1 |
| Straus, C | 1 |
| Pan, W | 1 |
| Liu, Y | 1 |
| Huang, Y | 1 |
| Yao, S | 1 |
| Li, J | 1 |
| Ju, H | 1 |
| Chen, L | 1 |
| Liao, L | 1 |
| Zuo, Z | 1 |
| Yan, Y | 1 |
| Yang, L | 1 |
| Chen, Y | 2 |
| Hou, J | 1 |
| Norouzi, P | 1 |
| Ganjali, MR | 1 |
| Daneshgar, P | 1 |
| Dinarvand, R | 1 |
| Moosavi-Movahedi, AA | 1 |
| Saboury, AA | 1 |
| Roy, N | 1 |
| Smith, ME | 1 |
| Allen, B | 1 |
| Merrill, RM | 1 |
| Chik, Z | 1 |
| Johnston, A | 1 |
| Tucker, AT | 1 |
| Burn, RT | 1 |
| Perrett, D | 1 |
| Ziegler, A | 1 |
| Lange, S | 1 |
| Bender, R | 1 |
| Kadioglu, Y | 1 |
| Atila, A | 1 |
| Schröter, J | 1 |
| Wandel, C | 1 |
| Böhrer, H | 1 |
| Schmidt, H | 1 |
| Böttiger, BW | 1 |
| Martin, E | 1 |
| Lehmann, U | 1 |
| Armstrong, VW | 6 |
| Schütz, E | 5 |
| Regel, G | 1 |
| Pape, D | 1 |
| Oellerich, M | 8 |
| Shetty, V | 1 |
| Gratt, BM | 1 |
| Flack, V | 1 |
| Dash, AK | 1 |
| Michels, AM | 1 |
| Lyons, G | 1 |
| Hopkins, PM | 1 |
| Toledano, A | 1 |
| Roizen, MF | 1 |
| Foss, J | 1 |
| Schoenwald, PK | 1 |
| Whalley, DG | 1 |
| Schluchter, MD | 1 |
| Gottlieb, A | 1 |
| Ryckman, JV | 1 |
| Bedocs, NM | 1 |
| Fabbri, A | 1 |
| Bianchi, GP | 1 |
| Marchesini, G | 1 |
| Yamamoto, S | 1 |
| Ashimura, H | 1 |
| Iwai, M | 1 |
| Matsumiya, N | 1 |
| Schwarzer, AC | 1 |
| Derby, R | 2 |
| Aprill, CN | 1 |
| Fortin, J | 1 |
| Kine, G | 2 |
| Bogduk, N | 1 |
| Cillo, U | 1 |
| Tedeschi, U | 1 |
| Carraro, P | 1 |
| Burra, P | 1 |
| Varagnolo, M | 1 |
| Ambrosino, G | 1 |
| Cionfoli, M | 1 |
| Brolese, A | 1 |
| Borin, L | 1 |
| Zanus, G | 1 |
| Fujii, T | 1 |
| Kurihara, Y | 1 |
| Arimoto, H | 1 |
| Mitsutsuka, Y | 1 |
| Arrigoni, A | 1 |
| Gindro, T | 1 |
| Aimo, G | 1 |
| Cappello, N | 1 |
| Meloni, A | 1 |
| Benedetti, P | 1 |
| Molino, GP | 1 |
| Verme, G | 1 |
| Rizzetto, M | 1 |
| Colonna-Romano, P | 4 |
| Padolina, R | 1 |
| Lingaraju, N | 4 |
| Braitman, LE | 3 |
| Courteix, C | 1 |
| Bardin, M | 1 |
| Chantelauze, C | 1 |
| Lavarenne, J | 1 |
| Eschalier, A | 1 |
| Bainton, CR | 1 |
| Strichartz, GR | 1 |
| Shiffman, ML | 1 |
| Luketic, VA | 1 |
| Sanyal, AJ | 1 |
| Duckworth, PF | 1 |
| Purdum, PP | 1 |
| Contos, MJ | 1 |
| Mills, AS | 1 |
| Edinboro, LE | 1 |
| Poklis, A | 2 |
| Fouad, AF | 1 |
| Rivera, EM | 1 |
| Krell, KV | 1 |
| Conte, B | 1 |
| Cutrufo, C | 1 |
| Manzini, S | 1 |
| O'Neal, CL | 1 |
| Freys, G | 1 |
| Tonsuwannont, W | 1 |
| Praisontarangkul, OA | 1 |
| Manorot, M | 1 |
| Klangwarnwong, D | 1 |
| Iossifidis, A | 1 |
| Autschbach, R | 1 |
| Falk, V | 1 |
| Lange, H | 1 |
| Walther, T | 1 |
| Mohr, FW | 1 |
| Dalichau, H | 1 |
| Burdelski, M | 2 |
| Nolte-Buchholtz, S | 1 |
| Curatolo, M | 1 |
| Scaramozzino, P | 1 |
| Venuti, FS | 1 |
| Orlando, A | 1 |
| Zbinden, AM | 1 |
| Grouls, RJ | 1 |
| Machielsen, E | 1 |
| Korsten, HH | 1 |
| Hellebrekers, LJ | 1 |
| Breimer, DD | 1 |
| Ackerman, EW | 1 |
| Large, V | 1 |
| Reynisdottir, S | 1 |
| Eleborg, L | 1 |
| van Harmelen, V | 1 |
| Strömmer, L | 1 |
| Arner, P | 1 |
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| Fraudeau, C | 1 |
| Vérette, E | 1 |
| Andreeva, M | 1 |
| Niedmann, PD | 3 |
| Wieland, E | 2 |
| Leclercq, I | 1 |
| Saliez, A | 1 |
| Wallemacq, PE | 1 |
| Horsmans, Y | 1 |
| Lambotte, L | 1 |
| Zanni, MP | 1 |
| von Greyerz, S | 1 |
| Schnyder, B | 1 |
| Wendland, T | 1 |
| Pichler, WJ | 1 |
| Shipkova, M | 3 |
| Sperber, AD | 1 |
| Fich, A | 1 |
| Sztarkier, I | 1 |
| Zirkin, HJ | 1 |
| Krugliak, P | 1 |
| Odes, HS | 1 |
| Hilzenrat, N | 1 |
| Gaspar, N | 1 |
| Zilberman, A | 1 |
| Broadhurst, NA | 1 |
| Bond, MJ | 1 |
| Laroche, N | 1 |
| Leneveu, A | 1 |
| Roux, A | 1 |
| Flouvat, B | 1 |
| Fabris, L | 1 |
| Jemmolo, RM | 1 |
| Toffolo, G | 1 |
| Paleari, D | 1 |
| Viaggi, S | 1 |
| Rigon, M | 1 |
| Casagrande, F | 1 |
| Lirussi, F | 1 |
| Strazzabosco, M | 1 |
| Cobelli, C | 1 |
| Okolicsanyi, L | 1 |
| Greim, CA | 1 |
| Brederlau, J | 1 |
| Kraus, I | 1 |
| Apfel, C | 1 |
| Thiel, H | 1 |
| Roewer, N | 1 |
| Muñoz, AE | 1 |
| Miguez, C | 1 |
| Rubio, M | 1 |
| Bartellini, M | 1 |
| Levi, D | 1 |
| Podestá, A | 1 |
| Niselman, V | 1 |
| Terg, R | 1 |
| Giannini, E | 1 |
| Botta, F | 1 |
| Fasoli, A | 1 |
| Ceppa, P | 1 |
| Risso, D | 1 |
| Lantieri, PB | 1 |
| Celle, G | 1 |
| Testa, R | 1 |
| Fein, JA | 1 |
| Callahan, JM | 1 |
| Boardman, CR | 1 |
| Gorelick, MH | 1 |
| Bo, LD | 1 |
| Mazzucchelli, P | 1 |
| Marzo, A | 1 |
| Vermylen, P | 1 |
| Pierard, P | 1 |
| Roufosse, C | 1 |
| Bosschaerts, T | 1 |
| Verhest, A | 1 |
| Sculier, JP | 1 |
| Ninane, V | 1 |
| Sporkert, F | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Subcutaneous Injection of Large Volumes of Tumescent Lidocaine and Epinephrine (TLE) by Laypersons: a Double-blind, Non-inferiority, Randomized Clinical Trial[NCT04733781] | Phase 2/Phase 3 | 36 participants (Anticipated) | Interventional | 2021-02-22 | Not yet recruiting | ||
| Fetal Electrophysiologic Abnormalities in High-risk Pregnancies Associated With Fetal Demise[NCT03775954] | 200 participants (Anticipated) | Observational | 2018-07-01 | Recruiting | |||
| A Randomized, Placebo-Controlled Trial to Evaluate Pain and Anxiety During Venipuncture in Pediatric Patients With or Without Pre-treatment by a Topical Anesthetic[NCT00676364] | Phase 4 | 114 participants (Actual) | Interventional | 2003-03-31 | Completed | ||
| Vulvar Vestibulitis Trial: Desipramine-Lidocaine[NCT00276068] | 128 participants (Anticipated) | Interventional | 2002-08-31 | Completed | |||
| Is Low Level Laser Therapy (LLLT) Effective for Reducing Pain Experienced by Women With Provoked Vestibulodynia?[NCT04234542] | 28 participants (Actual) | Interventional | 2021-02-18 | Completed | |||
| Effectiveness and Cost-utility of Somatocognitive Therapy Versus Treatment as Usual for Provoked (Localized) Vestibulodynia - a Randomized Clinical Trial (ProLoVe Study)[NCT04613713] | 128 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | |||
| Evaluation of Magnesium as Adjuvant to Ropivacaine for Sciatic Block at Popliteal Level.[NCT02198547] | 60 participants (Anticipated) | Interventional | 2014-03-31 | Enrolling by invitation | |||
| Comparing Pain Relief in Early Labor: Nitrous Oxide Versus Butorphonol Study[NCT01636999] | 0 participants (Actual) | Interventional | 2012-09-30 | Withdrawn | |||
| Development of a Breath Test for Monitoring Liver Metabolic Function in Patients With Chronic Liver Disease and Cirrhosis[NCT00244569] | Phase 3 | 120 participants (Anticipated) | Interventional | 2005-09-30 | Completed | ||
| IRB-HSR # 14073 Investigation of Pelvic Girdle Dysfunction in the Low Back Pain Population[NCT02950129] | Phase 2 | 55 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| A Cross Sectional Study to Determine the Association Between Diastasis Recti Abdominis and Sacroiliac Joint and Pelvic Floor Dysfunction Outcomes Among Postpartum Women Who Underwent C-section in UAE[NCT04519840] | 32 participants (Actual) | Observational [Patient Registry] | 2020-12-15 | Completed | |||
| A Randomized Control Trial of Ultrasound Guided IV Access in the Pediatric Emergency Department[NCT02125552] | 163 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| Investigation of the Presence of Piriformis Syndrome Accompanying Lumbar Radiculopathy[NCT05392933] | 40 participants (Anticipated) | Interventional | 2023-01-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Participant anxiety was measured by the study participant and the objective observer before (anticipatory), during (venipuncture) and after (recovery) venipuncture using a validated visual analog scale (VAS). The VAS is a validated scale that is used to detect small changes in many types of observations. The scale ranges from 0-100 scores on a scale, and here the higher scores indicate higher anxiety levels. Only the participant's mean venipuncture (during venipuncture) anxiety scores are presented in outcome measure results here. (NCT00676364)
Timeframe: During venipuncture
| Intervention | scores on a scale (Mean) |
|---|---|
| ControI Group Receiving Placebo Cream | 43.1 |
| Investigational Group | 40.5 |
"Pain was measured immediately after venipuncture by the participant using the six-point FACES scale. FACES in not an acronym, but rather a description of a pain scale that uses pictures of faces in various states of pain. The FACES pain scale is a common scale used to measure pain with scores on a scale. The scale we used had six points from zero (0) to five (5) indicating different levels of pain. Lower scores indicate lower levels of pain, and higher scores indicate higher levels of pain." (NCT00676364)
Timeframe: Pain was measured immediately after venipuncture.
| Intervention | scores on a scale (Mean) |
|---|---|
| ControI Group Receiving Placebo Cream | 2.2 |
| Investigational Group Receiving 4% Lidocaine Cream | 2.1 |
3 reviews available for lidocaine and Sensitivity and Specificity
| Article | Year |
|---|---|
Voltammetry of local anesthetics: theoretical and practical aspects.
Topics: Anesthetics, Local; Benzocaine; Drug Compounding; Electrochemical Techniques; Electrodes; Fluorocarb | 2021 |
Topical anesthetic creams.
Topics: Administration, Topical; Anesthetics, Local; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combinati | 2008 |
Piriformis syndrome: diagnosis, treatment, and outcome--a 10-year study.
Topics: Activities of Daily Living; Anesthetics, Local; Electric Stimulation; Electrodiagnosis; Female; H-Re | 2002 |
35 trials available for lidocaine and Sensitivity and Specificity
| Article | Year |
|---|---|
Pain assessment in conscious healthy volunteers: a crossover study evaluating the analgesia/nociception index.
Topics: Analgesia; Anesthetics, Local; Cross-Over Studies; Healthy Volunteers; Humans; Lidocaine; Nociceptio | 2017 |
[Epidural anaesthesia: Simulated intravascular test dose with S(+) ketamine, lidocaine and adrenaline. A prospective, randomized, double blind and placebo controlled study].
Topics: Adult; Anesthesia, Epidural; Double-Blind Method; Elective Surgical Procedures; Epinephrine; Female; | 2015 |
Forced coughing versus local anesthesia and pain associated with cervical biopsy: a randomized trial.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Biopsy, Needle; Cervix Uteri; Confidence Intervals; Coug | 2008 |
Cost-effectiveness analysis of anesthetic agents during peripheral intravenous cannulation in the pediatric emergency department.
Topics: Administration, Topical; Adolescent; Anesthetics; Catheterization, Peripheral; Child; Child, Prescho | 2008 |
Shoulder acute pain in primary health care: is retraining GPs effective? The SAPPHIRE randomized trial: a cost-effectiveness analysis.
Topics: Acute Disease; Anesthetics, Local; Anti-Inflammatory Agents; Cortisone; Cost-Benefit Analysis; Drug | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.
Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, | 2009 |
Predicting the efficacy of antiarrhythmic agents for interrupting persistent atrial fibrillation according to spectral analysis of the fibrillation waves on the surface ECG.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Cross-Over Studies; Electrocardiography | 2009 |
The value of clinical tests in acute full-thickness tears of the supraspinatus tendon: does a subacromial lidocaine injection help in the clinical diagnosis? A prospective study.
Topics: Acute Disease; Adult; Aged; Arthroscopy; Emergencies; Female; Humans; Lidocaine; Male; Middle Aged; | 2010 |
Minimum clinically significant VAS differences for simultaneous (paired) interval serial pain assessments.
Topics: Administration, Topical; Adult; Anesthetics, Local; Bites and Stings; Catheterization, Peripheral; C | 2003 |
Choice of electrocardiography lead does not affect the usefulness of the T-wave criterion for detecting intravascular injection of an epinephrine test dose in anesthetized children.
Topics: Anesthesia, Epidural; Anesthesia, General; Anesthetics, Local; Blood Pressure; Child, Preschool; Dou | 2003 |
Comparison of spinal vs general anesthesia via laryngeal mask airway in inguinal hernia repair.
Topics: Adult; Aged; Analysis of Variance; Anesthesia, General; Anesthesia, Spinal; Anesthetics, Intravenous | 2004 |
Improved application of Lidocaine/Prilocaine cream in children. A randomized and prospectively controlled study of two application regimes.
Topics: Anesthetics, Local; Catheterization; Child; Double-Blind Method; Drug Administration Schedule; Human | 2004 |
Quantitative three-phase bone scintigraphy in the evaluation of intravenous regional blockade treatment in patients with stage-I reflex sympathetic dystrophy of upper extremity.
Topics: Adult; Anesthesia, Conduction; Bone Diseases; Dexamethasone; Drug Combinations; Female; Humans; Inje | 2004 |
Lignocaine metabolite formation: an indicator for liver dysfunction and predictor of survival in surgical intensive care patients.
Topics: Aged; Bilirubin; Blood Pressure; Critical Care; Critical Illness; Female; Humans; Lidocaine; Liver; | 1995 |
Thermographic assessment of reversible inferior alveolar nerve deficit.
Topics: Adult; Cranial Nerve Diseases; Face; Humans; Hypesthesia; Image Interpretation, Computer-Assisted; L | 1994 |
Lignocaine test dose to detect intravenous injection.
Topics: Adult; Aged; Analgesia, Epidural; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hum | 1995 |
The hemodynamic responses to an intravenous test dose in vascular surgical patients.
Topics: Aged; Anesthesia, Epidural; Blood Pressure; Catheterization; Double-Blind Method; Epinephrine; Femal | 1995 |
Efficacy of an epidural test dose in adult patients anesthetized with isoflurane: lidocaine containing 15 micrograms epinephrine reliably increases arterial blood pressure, but not heart rate.
Topics: Adult; Anesthesia, General; Blood Pressure; Epinephrine; Female; Heart Rate; Humans; Isoflurane; Lid | 1995 |
Diagnostic accuracy of an intrathecal test dose in epidural analgesia.
Topics: Aged; Aged, 80 and over; Analgesia, Epidural; Double-Blind Method; Humans; Injections; Injections, S | 1994 |
Epidural test dose: lidocaine 100 mg, not chloroprocaine, is a symptomatic marker of i.v. injection in labouring parturients.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Dizziness; Double-Blind Method; F | 1993 |
Epidural test dose: isoproterenol is a reliable marker for intravascular injection in anesthetized adults.
Topics: Adult; Anesthesia, Epidural; Anesthetics, Inhalation; Biomarkers; Blood Pressure; Female; Heart Rate | 1996 |
Pharmacokinetics of oral lidocaine and nifedipine in patients with liver cirrhosis.
Topics: Administration, Oral; Adult; Anesthetics; Cross-Over Studies; Female; Hemodynamics; Humans; Lidocain | 1996 |
Assessment of metabolic liver function and hepatic blood flow during cardiopulmonary bypass.
Topics: Adult; Aged; Cardiopulmonary Bypass; Coronary Artery Bypass; Drug Monitoring; Humans; Indocyanine Gr | 1996 |
Pain provocation tests for the assessment of sacroiliac joint dysfunction.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Local; Arthralgia; Double-Blind Method; | 1998 |
Pain provocation tests for the assessment of sacroiliac joint dysfunction.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Local; Arthralgia; Double-Blind Method; | 1998 |
Pain provocation tests for the assessment of sacroiliac joint dysfunction.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Local; Arthralgia; Double-Blind Method; | 1998 |
Pain provocation tests for the assessment of sacroiliac joint dysfunction.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anesthetics, Local; Arthralgia; Double-Blind Method; | 1998 |
Lidocaine and monoethylglycinexylidide serum determinations to analyze liver function of cirrhotic patients after oral administration.
Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Bilirubin; Female; Half-Life; H | 1999 |
Reliability and sensitivity to change of various measures of hand function in relation to treatment of synovitis of the metacarpophalangeal joint in rheumatoid arthritis.
Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Combinations; | 2000 |
The diagnostic validity and therapeutic value of lumbar facet joint nerve blocks with or without adjuvant agents.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents; Female; Hu | 2000 |
Intravenous lidocaine infusion in the treatment of experimental human skin burns - digital colour image analysis of erythema development.
Topics: Adult; Anesthetics, Local; Burns; Cross-Sectional Studies; Dose-Response Relationship, Drug; Double- | 2000 |
Clinical application of NMP22 in the management of transitional cell carcinoma of the bladder.
Topics: Aged; Anesthetics, Local; Bayes Theorem; Biomarkers, Tumor; Carcinoma, Transitional Cell; Conscious | 2000 |
Better palpation of pain: reliability and validity of a new pressure pain protocol in TMD.
Topics: Adult; Analysis of Variance; Anesthetics, Local; Double-Blind Method; Facial Pain; Female; Humans; I | 2000 |
Hemodynamic assessment of local anesthetic administration by laser Doppler flowmetry.
Topics: Anesthetics, Local; Blood Pressure; Dental Anxiety; Double-Blind Method; Electrocardiography; Epinep | 2001 |
Hypotension in spinal anesthesia for cesarean section: a comparison of 0.5% hyperbaric bupivacaine and 5% hyperbaric lidocaine.
Topics: Adult; Anesthesia, Spinal; Blood Pressure Determination; Bupivacaine; Cesarean Section; Chi-Square D | 2001 |
The efficacy of simulated intravascular test dose in sedated patients.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Blood Pressure; Conscious Sedation; Electrocardiograp | 2001 |
Epidural test dose and intravascular injection in obstetrics: sensitivity, specificity, and lowest effective dose.
Topics: Analgesia, Epidural; Analgesia, Obstetrical; Anesthesiology; Dose-Response Relationship, Drug; Doubl | 1992 |
Heart rate response to an i.v. test dose of adrenaline and lignocaine with and without atropine pretreatment.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Conduction; Atropine; Epinephrine; Female; Heart Rate; H | 1991 |
101 other studies available for lidocaine and Sensitivity and Specificity
| Article | Year |
|---|---|
Small-molecule aggregates inhibit amyloid polymerization.
Topics: Acetophenones; Animals; Benzopyrans; beta-Lactamase Inhibitors; beta-Lactamases; Clioquinol; Congo R | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metab | 2009 |
Antibacterial effects of lidocaine and adrenaline.
Topics: Epinephrine; Escherichia coli; Humans; In Vitro Techniques; Lidocaine; Microbial Sensitivity Tests; | 2019 |
Ultrasound and Ultrasound-Guided Hip Injection Have High Accuracy in the Diagnosis of Femoroacetabular Impingement With Atypical Symptoms.
Topics: Adult; Anesthetics, Local; Betamethasone; Drug Combinations; Female; Femoracetabular Impingement; Gl | 2021 |
Tumescent contravenom: murine model for prehospital treatment of Naja naja neurotoxic snake envenomation.
Topics: Animals; Antivenins; Disease Models, Animal; Epinephrine; Female; Humans; Injections, Subcutaneous; | 2018 |
Measurement of lidocaine and 2,6-dimethylaniline in minipig plasma, skin, and dermal tapes using UHPLC with electrospray MS/MS.
Topics: Adhesives; Administration, Cutaneous; Aniline Compounds; Animals; Chromatography, High Pressure Liqu | 2018 |
Effect of Lidocaine on Viability and Gene Expression of Human Adipose-derived Mesenchymal Stem Cells: An in vitro Study.
Topics: Adipose Tissue; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug | 2019 |
In utero diagnosis of long QT syndrome by magnetocardiography.
Topics: Anti-Arrhythmia Agents; Cohort Studies; Electrocardiography; Female; Fetal Diseases; Genetic Associa | 2013 |
Validation of a thin-layer chromatography for the determination of hydrocortisone acetate and lidocaine in a pharmaceutical preparation.
Topics: Chemistry, Pharmaceutical; Chromatography, Thin Layer; Hydrocortisone; Lidocaine; Pharmaceutical Pre | 2014 |
Applying 'Sequential Windowed Acquisition of All Theoretical Fragment Ion Mass Spectra' (SWATH) for systematic toxicological analysis with liquid chromatography-high-resolution tandem mass spectrometry.
Topics: Chromatography, Liquid; Forensic Toxicology; Humans; Lidocaine; Midazolam; Morphine; Sensitivity and | 2015 |
Quantitation of pilsicainide in microscale samples of human biological fluids using liquid chromatography-tandem mass spectrometry.
Topics: Adult; Chromatography, Liquid; Drug Monitoring; Humans; Lidocaine; Linear Models; Male; Reproducibil | 2015 |
Validated RP-HPLC and TLC-Densitometric Methods for Analysis of Ternary Mixture of Cetylpyridinium Chloride, Chlorocresol and Lidocaine in Oral Antiseptic Formulation.
Topics: Acetonitriles; Anti-Infective Agents, Local; Cetylpyridinium; Chromatography, High Pressure Liquid; | 2016 |
On-line preconcentration strategy for the simultaneous quantification of three local anesthetics in human urine using CZE.
Topics: Anesthetics, Local; Bupivacaine; Electrophoresis, Capillary; Female; Humans; Lidocaine; Limit of Det | 2015 |
Nasal tampon packing using anesthetic lidocaine and chlorhexidine urinary lubricant gel.
Topics: Anesthetics; Chlorhexidine; Humans; Lidocaine; Lubricants; Rhinoplasty; Sensitivity and Specificity; | 2009 |
A predictor of positive drug provocation testing in individuals with saddle-back type ST-segment elevation.
Topics: Action Potentials; Adult; Brugada Syndrome; Electrocardiography; Female; Humans; Infusions, Intraven | 2009 |
Simultaneous determination of procaine, lidocaine, ropivacaine, tetracaine and bupivacaine in human plasma by high-performance liquid chromatography.
Topics: Amides; Bupivacaine; Chromatography, High Pressure Liquid; Drug Stability; Humans; Least-Squares Ana | 2010 |
Simultaneous determination of lidocaine hydrochloride, hydrocortisone and nystatin in a pharmaceutical preparation by RP-LC.
Topics: Chromatography, Reverse-Phase; Drug Contamination; Excipients; Hydrocortisone; Hydrogen-Ion Concentr | 2011 |
Development of an on-column enrichment technique based on C18-functionalized magnetic silica nanoparticles for the determination of lidocaine in rat plasma by high performance liquid chromatography.
Topics: Acetonitriles; Amides; Animals; Chromatography, High Pressure Liquid; Hydrophobic and Hydrophilic In | 2011 |
The anesthetic effect of lidocaine after varying times of phonophoresis.
Topics: Adult; Anesthetics, Local; Arm; Cross-Over Studies; Female; Humans; Lidocaine; Male; Pain Measuremen | 2011 |
Right ventricular dysfunction in patients with Brugada-like electrocardiography: a two dimensional strain imaging study.
Topics: Brugada Syndrome; Echocardiography; Elasticity Imaging Techniques; Electrocardiography; Female; Huma | 2011 |
Easy and fast LC-MS/MS determination of lidocaine and MEGX in plasma for therapeutic drug monitoring in neonates with seizures.
Topics: Animals; Cattle; Chromatography, Liquid; Drug Monitoring; Humans; Infant, Newborn; Lidocaine; Linear | 2012 |
The comparative sensitivity of three in vitro safety pharmacology models for the detection of lidocaine-induced cardiac effects.
Topics: Action Potentials; Animals; Atrial Function; Dose-Response Relationship, Drug; Drug Evaluation, Prec | 2012 |
Effect of local anesthetic on microorganisms in a murine model of surgical site infection.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Disease Models, Animal; Escherichia coli; Female; | 2012 |
Sensitivities of rat primary sensory afferent nerves to magnesium: implications for differential nerve blocks.
Topics: Action Potentials; Anesthetics, Local; Animals; Lidocaine; Magnesium; Magnesium Sulfate; Male; Nerve | 2013 |
A role for abdominal vagal afferents in lipopolysaccharide-induced hypotension.
Topics: Animals; Blood Pressure Determination; Capsaicin; Disease Models, Animal; Drug Interactions; Female; | 2002 |
Firing properties of the soma and axon of the abdominal stretch receptor neurons in the crayfish (Astacus leptodactylus).
Topics: Abdomen; Action Potentials; Adaptation, Physiological; Animals; Astacoidea; Axons; Electric Stimulat | 2002 |
The effect of local hematoma blocks on early fracture healing.
Topics: Analysis of Variance; Animals; Bupivacaine; Disease Models, Animal; Femoral Fractures; Fracture Fixa | 2002 |
[Determination of lidocaine in human spinal cord by high-performance liquid chromatography].
Topics: Anesthesia, Epidural; Chromatography, High Pressure Liquid; Forensic Medicine; Humans; Lidocaine; Re | 2000 |
[Pulse alterations related to the performance of flexible bronchoscopy].
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Bronchoscopy; Electrocardiography; Female; Heart | 2003 |
Free radical-induced damage in experimental peripheral nerve injection injury.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; Immunohistochemistry; Injury | 2003 |
Small-diameter endoscope enabled endoscopist to detect his own duodenal erosion.
Topics: Conscious Sedation; Duodenal Ulcer; Duodenoscopes; Duodenoscopy; Duodenum; Equipment Design; Equipme | 2003 |
The epidural test dose in obstetric anesthesia: it is not obsolete.
Topics: Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Catheterization; Epinephrine; Femal | 2003 |
Diagnostic values of tests for acromioclavicular joint pain.
Topics: Acromioclavicular Joint; Anesthetics, Local; Anti-Inflammatory Agents; Female; Humans; Joint Disease | 2004 |
Liquid chromatographic method for the determination of lidocaine and monoethylglycine xylidide in human serum containing various concentrations of bilirubin for the assessment of liver function.
Topics: Bilirubin; Calibration; Chromatography, High Pressure Liquid; Humans; Lidocaine; Liver Diseases; Liv | 2004 |
Primary nerve repair by muscle autografts prepared with local anesthetic.
Topics: Anesthesia, Local; Animals; Disease Models, Animal; Female; Lidocaine; Male; Microscopy, Confocal; M | 2004 |
Effect of lignocaine injection in carotid sinus on baroreceptor sensitivity during carotid endarterectomy.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Blood Pressure; Carotid Sinus; Combined Modality Therap | 2004 |
Neurophysiologic monitoring and pharmacologic provocative testing for embolization of spinal cord arteriovenous malformations.
Topics: Adult; Amobarbital; Anesthesia, General; Angiography; Arteriovenous Malformations; Cerebral Cortex; | 2004 |
Utility of nonaqueous capillary electrophoresis for the determination of lidocaine and its metabolites in human plasma: a comparison of ultraviolet and mass spectrometric detection.
Topics: Electrophoresis, Capillary; Humans; Lidocaine; Reproducibility of Results; Sensitivity and Specifici | 2004 |
Analysis of lidocaine and its major metabolite, monoethylglycinexylidide, in elk velvet antler by liquid chromatography with UV detection and confirmation by electrospray ionization tandem mass spectrometry.
Topics: Animals; Antlers; Chromatography, Liquid; Lidocaine; Male; Ruminants; Sensitivity and Specificity; S | 2005 |
[The study on identification of lidocaine in blood and CSF by GC/MS].
Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Dogs; Forensic Medicine; Gas Chromatography-Mass | 2005 |
Validation of liquid chromatographic method for analysis of lidocaine hydrochloride, dexamethasone acetate, calcium dobesilate, buthylhydroxyanisol and degradation product hydroquinone in suppositories and ointment.
Topics: Butylated Hydroxyanisole; Calcium Dobesilate; Chromatography, High Pressure Liquid; Dexamethasone; H | 2005 |
Effects of upper airway anaesthesia on respiratory-related evoked potentials in humans.
Topics: Administration, Inhalation; Adult; Analysis of Variance; Anesthesia, Local; Cohort Studies; Electroe | 2005 |
Determination of difenidol hydrochloride by capillary electrophoresis with electrochemiluminescence detection.
Topics: 2,2'-Dipyridyl; Clomiphene; Electrochemistry; Electrophoresis, Capillary; Hemoglobins; Humans; Lidoc | 2006 |
Simultaneous determination of ethamsylate, tramadol and lidocaine in human urine by capillary electrophoresis with electrochemiluminescence detection.
Topics: Electrophoresis, Capillary; Ethamsylate; Humans; Hydrogen-Ion Concentration; Lidocaine; Luminescent | 2006 |
Simultaneous determination of nikethamide and lidocaine in human blood and cerebrospinal fluid by high performance liquid chromatography.
Topics: Adult; Aged; Anesthetics, Local; Central Nervous System Stimulants; Chromatography, High Pressure Li | 2007 |
Development of fast Fourier transform continuous cyclic voltammetry at Au microelectrode in flowing solutions as a novel method for sub-nanomolar monitoring of lidocaine in injection and biological fluids.
Topics: Animals; Flow Injection Analysis; Fourier Analysis; Humans; Lidocaine; Male; Microelectrodes; Refere | 2007 |
Adductor spasmodic dysphonia versus muscle tension dysphonia: examining the diagnostic value of recurrent laryngeal nerve lidocaine block.
Topics: Adult; Aged; Anesthetics, Local; Autonomic Nerve Block; Diagnosis, Differential; Female; Humans; Inj | 2007 |
Validation and application of capillary electrophoresis for the analysis of lidocaine in a skin tape stripping study.
Topics: Anesthetics, Local; Calibration; Electrophoresis, Capillary; Humans; Lidocaine; Reproducibility of R | 2007 |
[Systematic reviews and meta-analyses].
Topics: Biometry; Humans; Lidocaine; Meta-Analysis as Topic; Myocardial Infarction; Peer Review; Research De | 2007 |
Development and validation of gas chromatography-mass spectroscopy method for determination of prilocaine HCl in human plasma using internal standard methodology.
Topics: Anesthetics, Local; Calibration; Chemical Fractionation; Gas Chromatography-Mass Spectrometry; Human | 2007 |
Monoethylglycinexylidide as an early predictor of posttraumatic multiple organ failure.
Topics: Adult; Aged; Bilirubin; Diagnosis, Differential; Female; Humans; Lidocaine; Liver Function Tests; Ma | 1995 |
Determination of pseudoephedrine hydrochloride in dosage forms by liquid chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography, Liquid; Dosage Forms; Drug Stability; Ephedrine; Lidocain | 1994 |
When is testing the test dose the wrong thing to do?
Topics: Anesthesia, Epidural; Catheterization; Epinephrine; Humans; Injections, Intravenous; Lidocaine; Sens | 1995 |
Hepatic lidocaine metabolism and liver histology.
Topics: Humans; Lidocaine; Liver; Liver Cirrhosis; Liver Function Tests; Sensitivity and Specificity | 1995 |
The value of the provocation response in lumbar zygapophyseal joint injections.
Topics: Adult; Bupivacaine; Female; Humans; Injections, Intra-Articular; Injections, Spinal; Lidocaine; Low | 1994 |
Early predictive markers of irreversible graft dysfunction after liver transplantation.
Topics: Actuarial Analysis; Adult; Aspartate Aminotransferases; Biomarkers; Factor V; Female; Graft Survival | 1994 |
Surface ionization organic mass spectrometry of imipramine, desipramine, clomipramine, and lidocaine.
Topics: Clomipramine; Desipramine; Humans; Imipramine; Lidocaine; Mass Spectrometry; Sensitivity and Specifi | 1994 |
Monoethylglicinexylidide test: a prognostic indicator of survival in cirrhosis.
Topics: Adult; Female; Follow-Up Studies; Humans; Lidocaine; Life Tables; Liver Cirrhosis; Liver Function Te | 1994 |
Study of the sensitivity of the diabetes-induced pain model in rats to a range of analgesics.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Aspirin; Clonidine; Diabetes Mellitus, Experi | 1994 |
Concentration dependence of lidocaine-induced irreversible conduction loss in frog nerve.
Topics: Action Potentials; Animals; Calcium Channels; Drug Interactions; In Vitro Techniques; Kinetics; Lido | 1994 |
Hepatic lidocaine metabolism and liver histology in patients with chronic hepatitis and cirrhosis.
Topics: Adult; Aged; Alanine Transaminase; Chronic Disease; Female; Hepatitis; Humans; Lidocaine; Liver; Liv | 1994 |
Epidural test dose with lidocaine in obstetrics: why ask questions?
Topics: Analgesia, Epidural; Double-Blind Method; Female; Humans; Labor, Obstetric; Lidocaine; Pregnancy; Pr | 1993 |
Accuracy of the Endex with variations in canal irrigants and foramen size.
Topics: Chi-Square Distribution; Dental Cavity Preparation; Dental Pulp Cavity; Ethanol; Lidocaine; Odontome | 1993 |
Electrocorticographic desynchronization after application of visceral and somatic noxious stimuli in urethane-anesthetized rats: effect of intrathecal administration of tachykinin (NK 1 or NK 2) receptor antagonists.
Topics: Acetylcholine; Administration, Topical; Anesthesia; Animals; Benzamides; Capsaicin; Cortical Synchro | 1996 |
Sensitive HPLC for simultaneous quantification of lidocaine and its metabolites monoethylglycinexylidide and glycinexylidide in serum.
Topics: Chromatography, High Pressure Liquid; Humans; Lidocaine; Liver Function Tests; Sensitivity and Speci | 1996 |
Lignocaine metabolism as an assessment of liver dysfunction.
Topics: Critical Care; Humans; Lidocaine; Liver Function Tests; Sensitivity and Specificity | 1996 |
Knee arthroscopy under local anaesthesia: results and evaluation of patients' satisfaction.
Topics: Adolescent; Adult; Anesthetics, Local; Arthroscopy; Bupivacaine; Female; Humans; Knee Joint; Lidocai | 1996 |
Prognostic value of the monoethylglycinexylidide test in pediatric liver transplant candidates.
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Female; Humans; Infant; Lidocaine; Liver Failu | 1996 |
Factors associated with hypotension and bradycardia after epidural blockade.
Topics: Adjuvants, Anesthesia; Adult; Aged; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, Local; B | 1996 |
Capillary gas chromatographic method for the determination of n-butyl-p-aminobenzoate and lidocaine in plasma samples.
Topics: Anesthetics, Local; Animals; Benzocaine; Blood Specimen Collection; Calibration; Cholinesterase Inhi | 1995 |
Lipolysis in human fat cells obtained under local and general anesthesia.
Topics: Abdomen; Adenylyl Cyclases; Adipocytes; Adrenergic beta-Agonists; Adult; Anesthesia, General; Anesth | 1997 |
On-line column-switching high-performance liquid chromatography analysis of cardiovascular drugs in serum with automated sample clean-up and zone-cutting technique to perform chiral separation.
Topics: Cardiovascular Agents; Chromatography, High Pressure Liquid; Diltiazem; Lidocaine; Linear Models; Me | 1997 |
Determination of MEGX by HPLC with fluorescence detection.
Topics: 4-Chloro-7-nitrobenzofurazan; Chromatography, High Pressure Liquid; Fluorescence Polarization Immuno | 1997 |
The monoethylglycinexylidide test does not correctly evaluate lidocaine metabolism after ischemic liver injury in the rat.
Topics: Animals; Bilirubin; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzymes; F | 1997 |
Allele-unrestricted presentation of lidocaine by HLA-DR molecules to specific alphabeta+ T cell clones.
Topics: Adult; Alleles; Anesthetics, Local; Animals; Antigen-Presenting Cells; Clone Cells; Drug Hypersensit | 1998 |
Determination of monoethylglycinexylidide by fluorescence polarization immunoassay in highly icteric serum samples: modified precipitation procedure and HPLC compared.
Topics: Chemical Precipitation; Chromatography, High Pressure Liquid; Fluorescence Polarization Immunoassay; | 1998 |
Premedication with Xylocaine spray does not lead to a false positive rapid urease test.
Topics: Anesthetics, Local; False Positive Reactions; Female; Helicobacter Infections; Helicobacter pylori; | 1998 |
Monoethylglycinexylidide (MEGX) liver function test is not compromised by 3-hydroxy MEGX in humans.
Topics: Animals; Fluorescence Polarization Immunoassay; Humans; Hydroxylation; Lidocaine; Liver Function Tes | 1998 |
Capillary gas chromatographic method for the measurement of small concentrations of monoethylglycinexylidide and lidocaine in plasma.
Topics: Chromatography, Gas; Humans; Lidocaine; Liver; Liver Cirrhosis; Liver Function Tests; Reproducibilit | 1998 |
The monoethylglycinexylidide test for grading of liver cirrhosis.
Topics: Adult; Discriminant Analysis; Female; Humans; Lidocaine; Liver Cirrhosis; Liver Function Tests; Male | 1999 |
Transnasal transesophageal echocardiography: a modified application mode for cardiac examination in ventilated patients.
Topics: Anatomy, Cross-Sectional; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Local; Bias; Bloo | 1999 |
Progressive liver functional impairment is associated with an increase in AST/ALT ratio.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chronic Disease; Clinical Enzyme Tests; Di | 1999 |
Predicting the need for topical anesthetic in the pediatric emergency department.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Catheterization, Peripheral; Child; | 1999 |
Highly sensitive bioassay of lidocaine in human plasma by high-performance liquid chromatography-tandem mass spectrometry.
Topics: Administration, Topical; Anesthetics, Local; Biological Assay; Biological Availability; Calibration; | 1999 |
Detection of bronchial preneoplastic lesions and early lung cancer with fluorescence bronchoscopy: a study about its ambulatory feasibility under local anaesthesis.
Topics: Ambulatory Care; Anesthesia, Local; Anesthetics, Local; Biopsy; Bronchial Neoplasms; Bronchoscopy; C | 1999 |
Use of headspace solid-phase microextraction (HS-SPME) in hair analysis for organic compounds.
Topics: Antidepressive Agents, Tricyclic; Cannabinoids; Chlormethiazole; Diphenhydramine; Gas Chromatography | 2000 |
High-performance liquid chromatography-tandem electrospray mass spectrometry for the determination of lidocaine and its metabolites in human plasma and urine.
Topics: Calibration; Chromatography, High Pressure Liquid; Humans; Lidocaine; Mass Spectrometry; Reproducibi | 2000 |
The capability of isolated hepatocytes and liver slices of donor livers to predict graft function after liver transplantation.
Topics: Adenosine Triphosphate; Adolescent; Adult; Biological Transport; Cell Count; Cell Survival; Cells, C | 2000 |
Fourth toe flexion sign: a new clinical sign for identification of the superficial peroneal nerve.
Topics: Adult; Anesthetics, Local; Female; Foot; Humans; Lidocaine; Male; Motor Neurons; Movement; Orthopedi | 2000 |
Computed tomography findings in patients with sacroiliac pain.
Topics: Adolescent; Adult; Anesthetics, Local; Ankylosis; Anti-Inflammatory Agents; Arthralgia; Betamethason | 2001 |
Culture of porcine hepatocytes: the dogma of exogenous matrix revisited.
Topics: Animals; Cell Division; Cells, Cultured; Culture Media; Diazepam; Extracellular Matrix; Hepatocytes; | 2001 |
Rapid and sensitive liquid chromatography-tandem mass spectrometry method for determination of monoethylglycinexylidide.
Topics: Chromatography, Liquid; Humans; Lidocaine; Mass Spectrometry; Reproducibility of Results; Sensitivit | 2001 |
Prediction of lidocaine tissue concentrations following different dose regimes during cardiac arrest using a physiologically based pharmacokinetic model.
Topics: Algorithms; Anesthetics, Local; Heart Arrest; Humans; Lidocaine; Models, Cardiovascular; Predictive | 2001 |
Involvement of the central nervous system in the protective effect of melanocortins in myocardial ischaemia/reperfusion injury.
Topics: Adrenocorticotropic Hormone; Animals; Central Nervous System; Disease Models, Animal; Dose-Response | 2002 |
Feasibility of the direct coupling of solid-phase extraction-pipette tips with a programmed-temperature vaporiser for gas chromatographic analysis of drugs in plasma.
Topics: Chromatography, Gas; Diazepam; Feasibility Studies; Lidocaine; Mass Spectrometry; Reproducibility of | 2002 |
Topical anesthesia: clarification.
Topics: Administration, Topical; Anesthesia, Local; Dermatology; Humans; Lidocaine; Sensitivity and Specific | 2002 |
Quantification of pilsicainide in serum by capillary electrophoresis.
Topics: Anti-Arrhythmia Agents; Electrophoresis, Capillary; Humans; Lidocaine; Reproducibility of Results; S | 2002 |
A quick, sensitive high-performance liquid chromatography assay for monoethylglycinexylidide and lignocaine in serum/plasma using solid-phase extraction.
Topics: Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Humans; Lidocaine; Liver Tra | 1992 |
PAF acether release on antigenic challenge. A method for the investigation of drug allergic reactions.
Topics: Antigens; Aspirin; Drug Hypersensitivity; Humans; Immunoglobulin E; Leukocytes; Lidocaine; Lymphocyt | 1992 |
Response to steroid and duration of radicular pain as predictors of surgical outcome.
Topics: Betamethasone; Delayed-Action Preparations; Humans; Lidocaine; Nerve Compression Syndromes; Predicti | 1992 |
Predictors of one-year pretransplant survival in patients with cirrhosis.
Topics: Humans; Indocyanine Green; Lidocaine; Liver Cirrhosis; Liver Function Tests; Liver Transplantation; | 1991 |