Page last updated: 2024-12-05

4-aminothiophenol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

4-Aminothiophenol (4-ATP) is an organic compound with the formula H2NC6H4SH. It is a colorless solid that is soluble in most organic solvents. 4-ATP is commonly used as a starting material in the synthesis of various organic compounds, including pharmaceuticals, dyes, and polymers. It is a versatile building block for the preparation of heterocyclic compounds, such as benzoxazoles and benzothiazoles. The synthesis of 4-ATP typically involves the reaction of 4-nitrochlorobenzene with sodium sulfide. The resulting 4-nitrothiophenol is then reduced to 4-aminothiophenol using a reducing agent such as iron or tin. 4-ATP has also been shown to have biological activity, including antibacterial and anticancer effects. It has been investigated for its potential use in the treatment of cancer and other diseases. Additionally, 4-ATP has been explored for its applications in materials science, such as the development of organic semiconductors and conductive polymers. The research on 4-ATP is driven by its diverse range of applications, including its potential in medicine, materials science, and organic synthesis.'

Cross-References

ID SourceID
PubMed CID14510
SCHEMBL ID49836
MeSH IDM0177189

Synonyms (45)

Synonym
AC-1080
1193-02-8
4-aminobenzene-1-thiol
EN300-40426
p-aminobenzenethiol
benzenethiol, 4-amino-
p-aminophenylmercaptan
4-mercaptoaniline
p-mercaptoaniline
einecs 214-763-4
ai3-52549
brn 0906904
p-aminothiophenol
4-aminobenzenethiol
4-aminothiophenol ,
benzenethiol, p-amino-
4-aminothiophenol, 97%
A0623
A804250
4-amino thiophenol
8x56v0k20x ,
unii-8x56v0k20x
4-aminophenyl mercaptan
BP-10049
FT-0633450
PS-3195
AKOS009156582
aminobenzenethiol, p-
p-aminophenyl mercaptan
4-mercaptobenzenamine
p-aminophenylthiol
SCHEMBL49836
4-aminothiphenol
4-amino-benzenethiol
p-amino-thiophenol
5-bromo-imidazo[1,2-a]pyridinehbr
W-108519
DTXSID1074466
mfcd00007880
4-aminothiophenol, technical grade, 90%
F0001-0317
4-aminothiophenol, tech grade
BCP18598
Q27271149
CS-W013508

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" This work presents the use of a sample translation technique (STT) as a means to minimize these adverse effects."( Use of a sample translation technique to minimize adverse effects of laser irradiation in surface-enhanced Raman spectrometry.
De Jesús, MA; Giesfeldt, KS; Sepaniak, MJ, 2003
)
0.32
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (103)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (1.94)18.7374
1990's1 (0.97)18.2507
2000's13 (12.62)29.6817
2010's75 (72.82)24.3611
2020's12 (11.65)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 65.84

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index65.84 (24.57)
Research Supply Index4.65 (2.92)
Research Growth Index6.04 (4.65)
Search Engine Demand Index106.00 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (65.84)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (0.96%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other103 (99.04%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]