Proteins > Epidermal growth factor receptor
Page last updated: 2024-08-07 16:58:10
Epidermal growth factor receptor
An epidermal growth factor receptor that is encoded in the genome of mouse. [OMA:Q01279, PRO:DNx]
Synonyms
EC 2.7.10.1
Research
Bioassay Publications (6)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
Compounds (5)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| rtki cpd | Mus musculus (house mouse) | IC50 | 0.1000 | 1 | 1 |
| staurosporine | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| osimertinib | Mus musculus (house mouse) | GI50 | 2.6000 | 1 | 1 |
| osimertinib | Mus musculus (house mouse) | IC50 | 0.0810 | 1 | 1 |
| naamidine a | Mus musculus (house mouse) | IC50 | 11.3000 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| 12-deoxyphorbol 13-acetate | Mus musculus (house mouse) | Effective concentration | 0.2200 | 1 | 1 |
Design, synthesis and biological evaluation of 4-aniline quinazoline derivatives conjugated with hydrogen sulfide (HEuropean journal of medicinal chemistry, , Sep-15, Volume: 202, 2020
Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors.Journal of medicinal chemistry, , 11-27, Volume: 62, Issue:22, 2019