perfluorohexanesulfonic acid : A perfluoroalkanesulfonic acid that is hexane-1-sulfonic acid in which all thirteen of the hydrogens that are attached to carbons have been replaced by fluorines. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 67734 |
| CHEMBL ID | 1906987 |
| CHEBI ID | 132448 |
| SCHEMBL ID | 332726 |
| MeSH ID | M0445675 |
| Synonym |
|---|
| perfluorohexanesulfonic acid |
| 355-46-4 |
| tridecafluorohexane-1-sulfonic acid |
| CHEBI:132448 |
| perfluorohexane sulfonic acid |
| perfluorohexane-1-sulfonic acid |
| 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexane-1-sulfonic acid |
| hsdb 8274 |
| einecs 206-587-1 |
| unii-zu6y1e592s |
| perfluorohexane-1-sulphonic acid |
| 1-hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro- |
| pfhxs |
| zu6y1e592s , |
| AKOS016005064 |
| SCHEMBL332726 |
| CS-B0907 |
| CHEMBL1906987 |
| 1-perfluorohexanesulfonic acid |
| 1-hexanesulfonic acid, tridecafluoro- |
| tridecafluorohexanesulfonic acid |
| DTXSID7040150 , |
| Q26833878 |
| perfluorohexanesulfonic acid 50 microg/ml in methanol/water |
| perfluorohexanesulphonic acid |
| mfcd00042453 |
| AMY7161 |
| perfluorohexanesulfonic acid 100 microg/ml in acetonitrile |
| 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexane-1-sulfonicacid |
| PD167508 |
| Excerpt | Reference |
|---|---|
| "Perfluorohexanesulfonic acid (PFHxS) is a short-chain perfluoroalkyl substance widely used to replace the banned perfluorooctanesulfonic acid (PFOS) in different industrial and household products. " | ( Tse, WKF; Ulhaq, ZS, 2023) |
| "Perfluorohexanesulfonic acid (PFHxS) is a short-chain perfluoroalkyl substance widely used to replace the banned perfluorooctanesulfonic acid (PFOS) in various industrial and household products. " | ( Boncan, DAT; Chan, TF; Tse, WKF; Ulhaq, ZS, 2023) |
| Class | Description |
|---|---|
| perfluoroalkanesulfonic acid | An organosulfonic acid in which the sulfo group is directly attached to a perfluoroalkyl group. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 16 (9.76) | 29.6817 |
| 2010's | 100 (60.98) | 24.3611 |
| 2020's | 48 (29.27) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (0.61%) | 5.53% |
| Reviews | 2 (1.21%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 1 (0.61%) | 0.25% |
| Other | 161 (97.58%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Article | Year |
|---|---|
| Derivation of a chronic reference dose for perfluorohexane sulfonate (PFHxS) for reproductive toxicity in mice. Regulatory toxicology and pharmacology : RTP, Volume: 108 | 2019 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |
| Article | Year |
|---|---|
| Sex-specific risk assessment of PFHxS using a physiologically based pharmacokinetic model. Archives of toxicology, Volume: 92, Issue: 3 | 2018 |
| Historical human exposure to perfluoroalkyl acids in the United States and Australia reconstructed from biomonitoring data using population-based pharmacokinetic modelling. Environment international, Volume: 108 | 2017 |
| A Simple Pharmacokinetic Model of Prenatal and Postnatal Exposure to Perfluoroalkyl Substances (PFASs). Environmental science & technology, Jan-19, Volume: 50, Issue: 2 | 2016 |
| Comparative pharmacokinetics of perfluorohexanesulfonate (PFHxS) in rats, mice, and monkeys. Reproductive toxicology (Elmsford, N.Y.), Volume: 33, Issue: 4 | 2012 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |