lorazepam has been researched along with Sensitivity and Specificity in 17 studies
Lorazepam: A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The developed method has been successfully applied for pharmacokinetic study of the drug in man." | 1.33 | A fast and sensitive liquid chromatographic-tandem mass spectrometric method for assay of lorazepam and application to pharmacokinetic analysis. ( Luo, J; Zhu, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, H | 1 |
| Sun, J | 1 |
| Sui, X | 1 |
| Liu, J | 1 |
| Yan, Z | 1 |
| Liu, X | 1 |
| Sun, Y | 1 |
| He, Z | 1 |
| Deng, F | 1 |
| Tang, Q | 1 |
| Zeng, G | 1 |
| Wu, H | 1 |
| Zhang, N | 1 |
| Zhong, N | 1 |
| Feltner, DE | 1 |
| Harness, J | 1 |
| Brock, J | 1 |
| Sambunaris, A | 1 |
| Cappelleri, JC | 1 |
| Morlock, R | 1 |
| Hunt, CH | 1 |
| Wood, CP | 1 |
| Lane, JI | 1 |
| Bolster, BD | 1 |
| Bernstein, MA | 1 |
| Witte, RJ | 1 |
| Mikel, C | 1 |
| Pesce, AJ | 1 |
| Rosenthal, M | 1 |
| West, C | 1 |
| Pham-Huy, C | 1 |
| Villain-Pautet, G | 1 |
| Hua, H | 1 |
| Chikhi-Chorfi, N | 1 |
| Galons, H | 1 |
| Thevenin, M | 1 |
| Claude, JR | 1 |
| Warnet, JM | 1 |
| Zhu, H | 1 |
| Luo, J | 1 |
| Meijboom, WB | 1 |
| Mollet, NR | 1 |
| Van Mieghem, CA | 1 |
| Kluin, J | 1 |
| Weustink, AC | 1 |
| Pugliese, F | 1 |
| Vourvouri, E | 1 |
| Cademartiri, F | 1 |
| Bogers, AJ | 1 |
| Krestin, GP | 1 |
| de Feyter, PJ | 1 |
| Musteata, FM | 1 |
| de Lannoy, I | 1 |
| Gien, B | 1 |
| Pawliszyn, J | 1 |
| Kondo, T | 1 |
| Buss, DC | 1 |
| Routledge, PA | 1 |
| Agbuya, PG | 1 |
| Li, L | 1 |
| Miles, MV | 1 |
| Zaritsky, AL | 1 |
| Morris, AD | 1 |
| Way, BA | 1 |
| Walton, KG | 1 |
| Koenig, JW | 1 |
| Eveland, BJ | 1 |
| Scott, MG | 1 |
| Meatherall, R | 1 |
| Fraser, AD | 1 |
| Augsburger, M | 1 |
| Rivier, L | 1 |
| Mangin, P | 1 |
| Kanazawa, H | 1 |
| Kunito, Y | 1 |
| Matsushima, Y | 1 |
| Okubo, S | 1 |
| Mashige, F | 1 |
| Noerr, B | 1 |
| Berzas Nevado, JJ | 1 |
| Castañeda Peñalvo, G | 1 |
| Pinilla Calderón, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| coRonary assEssment of Preoperative vaLvulopathy pAtients Using ComputEd Tomographic Angiography (REPLACE)[NCT02632617] | 2,644 participants (Anticipated) | Observational [Patient Registry] | 2015-12-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for lorazepam and Sensitivity and Specificity
| Article | Year |
|---|---|
Clinical evaluation of the Daily Assessment of Symptoms-Anxiety (DAS-A): a new instrument to assess the onset of symptomatic improvement in generalized anxiety disorder.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Double-Blind Method; Female; Humans; Lorazepam; Male; | 2009 |
16 other studies available for lorazepam and Sensitivity and Specificity
| Article | Year |
|---|---|
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metab | 2009 |
Effectiveness of digital infrared thermal imaging in detecting lower extremity deep venous thrombosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Female; Humans; Infrared Rays; Lorazepam; L | 2015 |
Wide, short bore magnetic resonance at 1.5 t: reducing the failure rate in claustrophobic patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Brain Diseases; Child; Equipment De | 2011 |
Therapeutic monitoring of benzodiazepines in the management of pain: current limitations of point of care immunoassays suggest testing by mass spectrometry to assure accuracy and improve patient safety.
Topics: Benzodiazepines; Chromatography, Liquid; Clonazepam; False Negative Reactions; False Positive Reacti | 2012 |
Separation of oxazepam, lorazepam, and temazepam enantiomers by HPLC on a derivatized cyclodextrin-bonded phase: application to the determination of oxazepam in plasma.
Topics: Animals; Benzodiazepinones; Chromatography, High Pressure Liquid; Cyclodextrins; Lorazepam; Optical | 2002 |
A fast and sensitive liquid chromatographic-tandem mass spectrometric method for assay of lorazepam and application to pharmacokinetic analysis.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Humans; Lorazepam; Male; Mass Spectrometry; Refere | 2005 |
Pre-operative computed tomography coronary angiography to detect significant coronary artery disease in patients referred for cardiac valve surgery.
Topics: Adrenergic beta-Antagonists; Aged; Coronary Angiography; Coronary Stenosis; Female; Heart Rate; Hear | 2006 |
Blood sampling without blood draws for in vivo pharmacokinetic studies in rats.
Topics: Acetonitriles; Animals; Anti-Anxiety Agents; Area Under Curve; Buffers; Calibration; Diazepam; Half- | 2008 |
A method for rapid determination of lorazepam by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Lorazepam; Sensitivity and Specificity | 1993 |
Development of a fluorescence polarization immunoassay for lorazepam quantification.
Topics: Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Fluorescence Polarization Immunoassay; Hu | 1996 |
Comparison between the CEDIA and EMIT II immunoassays for the determination of benzodiazepines.
Topics: Benzodiazepines; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Lorazepam; Medical Recor | 1998 |
Comparison of four immunoassays for the detection of lorazepam in urine.
Topics: Enzyme Multiplied Immunoassay Technique; Escherichia coli; Female; Fluorescence Polarization Immunoa | 1998 |
Comparison of different immunoassays and GC-MS screening of benzodiazepines in urine.
Topics: Anti-Anxiety Agents; Benzodiazepines; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Lor | 1998 |
Stereospecific analysis of lorazepam in plasma by chiral column chromatography with a circular dichroism-based detector.
Topics: Anti-Anxiety Agents; Chromatography, Liquid; Circular Dichroism; GABA Modulators; Humans; Lorazepam; | 2000 |
Lorazepam.
Topics: Anti-Anxiety Agents; Anxiety; Asphyxia Neonatorum; Dose-Response Relationship, Drug; Female; Humans; | 2000 |
Determination of lormetazepam and its main metabolite in serum using micellar electrokinetic capillary chromatography with direct injection and ultraviolet absorbance detection.
Topics: Anti-Anxiety Agents; Benzodiazepines; Buffers; Chromatography, Micellar Electrokinetic Capillary; Hu | 2002 |