| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
hydrochloric acid
Hydrochloric Acid: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.. hydrogen chloride : A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms. | 1.99 | 1 | 0 | chlorine molecular entity;
gas molecular entity;
hydrogen halide;
mononuclear parent hydride | mouse metabolite |
phenol
[no description available] | 2.46 | 2 | 0 | phenols | antiseptic drug;
disinfectant;
human xenobiotic metabolite;
mouse metabolite |
2-aminoethoxydiphenyl borate
2-aminoethoxydiphenyl borate: is a novel membrane-penetrable modulator and transient receptor potential channel blocker; structure in first source; do not confuse with 2-APB cpd. 2-aminoethoxydiphenylborane : An organoboron compound that is diphenylborane in which the borane hydrogen is replaced by a 2-aminoethoxy group. | 2.06 | 1 | 0 | organoboron compound;
primary amino compound | calcium channel blocker;
IP3 receptor antagonist;
potassium channel opener |
3-nitrobenzeneboronic acid
[no description available] | 1.99 | 1 | 0 | | |
benzo(b)thiophene-2-boronic acid
benzo(b)thiophene-2-boronic acid: inhibits AmpC beta-lactamase; structure in first source | 1.99 | 1 | 0 | | |
diphenhydramine
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.. diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.. antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration. | 2.08 | 1 | 0 | ether;
tertiary amino compound | anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative |
ether
Ether: A mobile, very volatile, highly flammable liquid used as an inhalation anesthetic and as a solvent for waxes, fats, oils, perfumes, alkaloids, and gums. It is mildly irritating to skin and mucous membranes.. ether : An organooxygen compound with formula ROR, where R is not hydrogen.. diethyl ether : An ether in which the oxygen atom is linked to two ethyl groups. | 2.21 | 1 | 0 | ether;
volatile organic compound | inhalation anaesthetic;
non-polar solvent;
refrigerant |
lysine
Lysine: An essential amino acid. It is often added to animal feed.. lysine : A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.. L-lysine : An L-alpha-amino acid; the L-isomer of lysine. | 1.99 | 1 | 0 | aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid | algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite |
histidine
Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. | 2.39 | 2 | 0 | amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |
arginine
Arginine: An essential amino acid that is physiologically active in the L-form.. arginine : An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group. | 1.99 | 1 | 0 | arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
boranes
Boranes: The collective name for the boron hydrides, which are analogous to the alkanes and silanes. Numerous boranes are known. Some have high calorific values and are used in high-energy fuels. (From Grant & Hackh's Chemical Dictionary, 5th ed). borane : The simplest borane, consisting of a single boron atom carrying three hydrogens.. boranes : The molecular hydrides of boron. | 2.76 | 3 | 0 | boranes;
mononuclear parent hydride | |
acetonitrile
acetonitrile: RN given refers to unlabeled cpd. acetonitrile : A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group. | 2.05 | 1 | 0 | aliphatic nitrile;
volatile organic compound | EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent |
benzohydrol
diphenylmethanol : A secondary alcohol that is diphenylmethane which carries a hydroxy group at position 1. | 2.08 | 1 | 0 | benzyl alcohols;
secondary alcohol | bacterial xenobiotic metabolite;
human urinary metabolite;
human xenobiotic metabolite;
rat metabolite |
boric acid
[no description available] | 2.08 | 1 | 0 | boric acids | astringent |
sodium hydroxide
Sodium Hydroxide: A highly caustic substance that is used to neutralize acids and make sodium salts. (From Merck Index, 11th ed) | 2.05 | 1 | 0 | alkali metal hydroxide | |
n-butylboronic acid
[no description available] | 1.99 | 1 | 0 | | |
5,6-dihydroxy-2-methylaminotetralin
5,6-dihydroxy-2-methylaminotetralin: beta2 adrenergic agonist; coronary vasodilator in vivo; cyclic dopamine analog; synonym M-8 refers to HBr; RN given refers to parent cpd | 1.99 | 1 | 0 | | |
benzeneboronic acid
[no description available] | 3.14 | 5 | 0 | boronic acids | |
oxazolidin-2-one
Oxazolidinones: Derivatives of oxazolidin-2-one. They represent an important class of synthetic antibiotic agents.. oxazolidin-2-one : An oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2.. oxazolidinone : An oxazolidine containing one or more oxo groups. | 1.97 | 1 | 0 | carbamate ester;
oxazolidinone | metabolite |
4-bromophenylboric acid
[no description available] | 1.99 | 1 | 0 | | |
3-aminobenzeneboronic acid
[no description available] | 1.99 | 1 | 0 | | |
pentosidine
pentosidine: structure given in first source. pentosidine : An imidazopyridine having norleucine and ornithine residues attached via their side-chains at the 4- and 2-positions respectively. | 1.99 | 1 | 0 | imidazopyridine;
non-proteinogenic L-alpha-amino acid | biomarker;
cross-linking reagent |
delta-hydroxylysylnorleucine
delta-hydroxylysylnorleucine: RN given refers to cpd without isomeric designation | 1.98 | 1 | 0 | | |
methaneboronic acid
[no description available] | 2.08 | 1 | 0 | | |
n-dansyl-3-aminobenzeneboronic acid
N-dansyl-3-aminobenzeneboronic acid: potent serine protease inhibitor; fluorescent boronic acid which reversibly binds to bacterial cell walls; structure given in first source | 1.99 | 1 | 0 | | |
histidinohydroxymerodesmosine
histidinohydroxymerodesmosine: structure | 1.98 | 1 | 0 | | |
4-methoxyphenylboronic acid
4-methoxyphenylboronic acid: structure in first source | 1.99 | 1 | 0 | | |
1,4-phenylenebis(boronic acid)
1,4-phenylenebis(boronic acid): structure in first source | 1.99 | 1 | 0 | | |
2-formylphenylboronic acid
2-formylphenylboronic acid: structure in first source | 1.99 | 1 | 0 | | |
fibrin
Fibrin: A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot. | 1.98 | 1 | 0 | peptide | |
thiophene-3-boronic acid
thiophene-3-boronic acid: structure in first source | 1.99 | 1 | 0 | | |
pyridine triphenylborane
pyridine triphenylborane: an antifouling biocide | 2.07 | 1 | 0 | | |
ribose
ribopyranose : The pyranose form of ribose. | 1.99 | 1 | 0 | D-ribose;
ribopyranose | |
desmosine
Desmosine: A rare amino acid found in elastin, formed by condensation of four molecules of lysine into a pyridinium ring. | 1.98 | 1 | 0 | aromatic amino acid | |
muramidase
Muramidase: A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC 3.2.1.17. | 1.99 | 1 | 0 | | |