gemfibrozil has been researched along with Sensitivity and Specificity in 14 studies
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Niacin was the most efficient agent for reducing low-density lipoprotein cholesterol levels, having an average cost over 5 years of $139 per percent reduction in low-density lipoprotein cholesterol level." | 2.38 | Reducing high blood cholesterol level with drugs. Cost-effectiveness of pharmacologic management. ( Eisenberg, JM; Glick, H; Jacobson, TA; Kinosian, B; Koffer, H; Schulman, KA; Willian, MK, 1990) |
| " This method was successfully used to study the pharmacokinetics and bioavailability of CA in rats." | 1.35 | High-performance liquid chromatography method for determination of carnosic acid in rat plasma and its application to pharmacokinetic study. ( Jiang, Y; Li, X; Lu, W; Tu, P; Wang, L; Wu, L; Yan, H; Yu, C; Zhang, K, 2009) |
| " The application of the assay in an oral pharmacokinetic study in rats co-administered with RST and GFZ is described." | 1.33 | Simultaneous quantitation of rosuvastatin and gemfibrozil in human plasma by high-performance liquid chromatography and its application to a pharmacokinetic study. ( Kumar, TR; Mullangi, R; Shitut, NR; Srinivas, NR; Vinu, MC; Vittal, S, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, H | 1 |
| Sun, J | 1 |
| Sui, X | 1 |
| Liu, J | 1 |
| Yan, Z | 1 |
| Liu, X | 1 |
| Sun, Y | 1 |
| He, Z | 1 |
| Kahma, H | 1 |
| Filppula, AM | 1 |
| Launiainen, T | 1 |
| Viinamäki, J | 1 |
| Neuvonen, M | 1 |
| Evangelista, EA | 1 |
| Totah, RA | 1 |
| Backman, JT | 1 |
| Li, P | 1 |
| Li, Z | 1 |
| Beck, WD | 1 |
| Callahan, PM | 1 |
| Terry, AV | 1 |
| Bar-Peled, M | 1 |
| Bartlett, MG | 1 |
| Yan, H | 1 |
| Wang, L | 1 |
| Li, X | 1 |
| Yu, C | 1 |
| Zhang, K | 1 |
| Jiang, Y | 1 |
| Wu, L | 1 |
| Lu, W | 1 |
| Tu, P | 1 |
| Tzanavaras, PD | 1 |
| Themelis, DG | 1 |
| Rigas, P | 1 |
| El-Din, MM | 1 |
| Attia, KA | 1 |
| Nassar, MW | 1 |
| Kaddah, MM | 1 |
| Zhu, D | 1 |
| Ganji, SH | 1 |
| Kamanna, VS | 1 |
| Kashyap, ML | 1 |
| Roadcap, BA | 1 |
| Musson, DG | 1 |
| Rogers, JD | 1 |
| Zhao, JJ | 1 |
| Geelen, MJ | 1 |
| Vittal, S | 1 |
| Shitut, NR | 1 |
| Kumar, TR | 1 |
| Vinu, MC | 1 |
| Mullangi, R | 1 |
| Srinivas, NR | 1 |
| Tallis, GA | 1 |
| Shephard, MD | 1 |
| Whiting, MJ | 1 |
| Rubins, HB | 1 |
| Robins, SJ | 1 |
| Iwane, MK | 1 |
| Boden, WE | 1 |
| Elam, MB | 1 |
| Fye, CL | 1 |
| Gordon, DJ | 1 |
| Schaefer, EJ | 1 |
| Schectman, G | 1 |
| Wittes, JT | 1 |
| Hermening, A | 1 |
| Gräfe, AK | 1 |
| Baktir, G | 1 |
| Mutschler, E | 1 |
| Spahn-Langguth, H | 1 |
| Schulman, KA | 1 |
| Kinosian, B | 1 |
| Jacobson, TA | 1 |
| Glick, H | 1 |
| Willian, MK | 1 |
| Koffer, H | 1 |
| Eisenberg, JM | 1 |
1 review available for gemfibrozil and Sensitivity and Specificity
| Article | Year |
|---|---|
Reducing high blood cholesterol level with drugs. Cost-effectiveness of pharmacologic management.
Topics: Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Colestipol; Cost-Benefit A | 1990 |
1 trial available for gemfibrozil and Sensitivity and Specificity
| Article | Year |
|---|---|
Rationale and design of the Department of Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial (HIT) for secondary prevention of coronary artery disease in men with low high-density lipoprotein cholesterol and desirable low-density lip
Topics: Adult; Aged; Cause of Death; Cholesterol, HDL; Cholesterol, LDL; Clinical Protocols; Coronary Diseas | 1993 |
12 other studies available for gemfibrozil and Sensitivity and Specificity
| Article | Year |
|---|---|
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metab | 2009 |
Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8.
Topics: Amiodarone; Clopidogrel; Cytochrome P-450 CYP2C8; Gemfibrozil; Glucuronides; Humans; Kinetics; Micro | 2019 |
Bio-generation of stable isotope-labeled internal standards for absolute and relative quantitation of phase II drug metabolites in plasma samples using LC-MS/MS.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimida | 2015 |
High-performance liquid chromatography method for determination of carnosic acid in rat plasma and its application to pharmacokinetic study.
Topics: Abietanes; Animals; Biological Availability; Chromatography, High Pressure Liquid; Gemfibrozil; Line | 2009 |
Automated zone-sampling dilution by coupling sequential injection analysis to high-throughput HPLC for the direct determination of gemfibrozil.
Topics: Chromatography, High Pressure Liquid; Gemfibrozil; Humans; Hypolipidemic Agents; Molecular Structure | 2009 |
Two different spectrofluorimetric methods for simultaneous determination of gemfibrozil and rosiglitazone in human plasma.
Topics: Buffers; Calibration; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Hypoglycemic Agents; In Vitro | 2010 |
Effect of gemfibrozil on apolipoprotein B secretion and diacylglycerol acyltransferase activity in human hepatoblastoma (HepG2) cells.
Topics: Acyltransferases; Apolipoproteins B; Diacylglycerol O-Acyltransferase; Gemfibrozil; Hepatoblastoma; | 2002 |
Sensitive method for the quantitative determination of gemfibrozil in dog plasma by liquid-liquid cartridge extraction and liquid chromatography-tandem mass spectrometry.
Topics: Animals; Dogs; Gemfibrozil; Hypolipidemic Agents; Mass Spectrometry; Reproducibility of Results; Sen | 2003 |
Measurement of diacylglycerol acyltransferase activity in isolated hepatocytes.
Topics: Acyltransferases; Animals; Cell Membrane Permeability; Cells, Cultured; Cytosol; Diacylglycerol O-Ac | 2003 |
Simultaneous quantitation of rosuvastatin and gemfibrozil in human plasma by high-performance liquid chromatography and its application to a pharmacokinetic study.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Fluorobenzenes; Gemfibrozil; Humans; | 2006 |
Lipoprotein profiling by high performance gel chromatography.
Topics: Apolipoprotein A-I; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Chroma | 1994 |
Gemfibrozil and its oxidative metabolites: quantification of aglycones, acyl glucuronides, and covalent adducts in samples from preclinical and clinical kinetic studies.
Topics: Animals; Chromatography, High Pressure Liquid; Gemfibrozil; Glucuronides; Humans; Hyperlipidemias; H | 2000 |