Proteins > tumor necrosis factor
Page last updated: 2024-08-07 12:35:04

tumor necrosis factor

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (79)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
1,10-phenanthrolineHomo sapiens (human)Potency33.491510
hexachloropheneHomo sapiens (human)Potency74.978010
nifedipineHomo sapiens (human)Potency10.590910
triamtereneHomo sapiens (human)Potency47.307910
4-toluenesulfonamideHomo sapiens (human)Potency3.349110
2,4,5-trichlorophenolHomo sapiens (human)Potency74.978010
dianisidineHomo sapiens (human)Potency42.163210
benzo(e)pyreneHomo sapiens (human)Potency29.849310
benzo(b)fluorantheneHomo sapiens (human)Potency74.978010
luminolHomo sapiens (human)Potency59.557210
gentian violetHomo sapiens (human)Potency42.163210
2,3,5-trichlorophenolHomo sapiens (human)Potency74.978010
ethidium bromideHomo sapiens (human)Potency37.578010
n-(1-naphthyl)ethylenediamine dihydrochlorideHomo sapiens (human)Potency42.163210
1,5-naphthalenediamineHomo sapiens (human)Potency42.163210
2,3,4,5-tetrachlorophenateHomo sapiens (human)Potency74.978010
hc blue no. 2Homo sapiens (human)Potency47.307910
3,3',5,5'-tetramethylbenzidineHomo sapiens (human)Potency66.824210
daunorubicin hydrochlorideHomo sapiens (human)Potency13.333210
crystal violet lactoneHomo sapiens (human)Potency42.163210
doxorubicin hydrochlorideHomo sapiens (human)Potency8.412710
riboflavinHomo sapiens (human)Potency53.080410
digoxinHomo sapiens (human)Potency0.375810
malachite greenHomo sapiens (human)Potency42.163210
1,8-dinitro-4,5-dihydroxyanthraquinoneHomo sapiens (human)Potency3.349110
amphotericin bHomo sapiens (human)Potency42.163210
toxapheneHomo sapiens (human)Potency74.978010
5,7-dihydroxy-4-methylcoumarinHomo sapiens (human)Potency7.497810
phenylmercuric acetateHomo sapiens (human)Potency0.595610

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
thioflavin tHomo sapiens (human)IC500.762010
8-(4-benzenesulfonylamino)quinolineHomo sapiens (human)IC502.737510
moronic acidHomo sapiens (human)IC5010.880010
N-[1-[(4-methylphenyl)methyl]-2-benzimidazolyl]-2-furancarboxamideHomo sapiens (human)IC5020.000010
3-methyl-7-pentyl-8-(2-phenylethylthio)purine-2,6-dioneHomo sapiens (human)IC5020.000020
2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)thio]-N-(4-phenyl-2-thiazolyl)acetamideHomo sapiens (human)IC506.129010
7-butyl-8-[[4-(3-chlorophenyl)-1-piperazinyl]methyl]-1,3-dimethylpurine-2,6-dioneHomo sapiens (human)IC504.520020
iFSP1Homo sapiens (human)IC506.058510
3-methyl-7-(phenylmethyl)-8-(propan-2-ylthio)purine-2,6-dioneHomo sapiens (human)IC5020.000020
6-(chloromethyl)-N2-(3-methylphenyl)-1,3,5-triazine-2,4-diamineHomo sapiens (human)IC5014.601020
4-[(2-bromophenoxy)methyl]-N-[4-[(3,5-dimethyl-1-pyrazolyl)methyl]phenyl]benzamideHomo sapiens (human)IC504.343010
1-(4-methylphenyl)sulfonyl-2-benzimidazolamineHomo sapiens (human)IC5020.000040
1-(4-chlorophenyl)sulfonyl-2-benzimidazolamineHomo sapiens (human)IC5020.000010
2-[(4-bromophenoxy)methyl]-5-[2-(3,4-dimethoxyphenyl)ethylamino]-4-oxazolecarbonitrileHomo sapiens (human)IC505.857510
N-(2-phenyl-5-benzotriazolyl)-2,3-dihydro-1,4-benzodioxin-6-carboxamideHomo sapiens (human)IC505.312010
3-amino-8-methyl-N-[4-(4-morpholinyl)phenyl]-2-thieno[2,3-b]quinolinecarboxamideHomo sapiens (human)IC505.496510
cyqualonHomo sapiens (human)IC503.596510
3-methyl-2-benzofurancarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] esterHomo sapiens (human)IC5020.000020
4-[4-(phenylmethyl)-1-piperidinyl]thieno[2,3-d]pyrimidineHomo sapiens (human)IC5020.000010
2-chloro-N-(2-phenyl-5-propyl-3-pyrazolyl)acetamideHomo sapiens (human)IC504.549010
4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(1-pyrrolidinylsulfonyl)phenyl]benzamideHomo sapiens (human)IC500.639010
4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(1-piperidinylsulfonyl)phenyl]benzamideHomo sapiens (human)IC500.616010
1-[(7-chloro-4-quinolinyl)amino]-3-(2,4-dichlorophenyl)thioureaHomo sapiens (human)IC5011.179510
2-chloro-1-[4-[(3-methylphenyl)methyl]-1-piperazinyl]ethanoneHomo sapiens (human)IC5013.885510
4-acetamido-N-[4-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-thiazolyl]benzamideHomo sapiens (human)IC5020.000010
2-[(4-chlorophenyl)thio]-1-methyl-3-indolecarboxaldehydeHomo sapiens (human)IC500.748510
5-methyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-thieno[2,3-d]pyrimidinamineHomo sapiens (human)IC501.606010
N-[4-methyl-5-[2-(3-nitroanilino)-4-thiazolyl]-2-thiazolyl]acetamideHomo sapiens (human)IC5011.146510
2-[(9-tert-butyl-1,5-dicyano-2-oxo-3-azaspiro[5.5]undec-4-en-4-yl)thio]-N-cyclohexylacetamideHomo sapiens (human)IC509.315510
N-[4-[(3-acetylphenyl)sulfamoyl]phenyl]-1-piperidinecarboxamideHomo sapiens (human)IC5014.278010
1-(benzenesulfonyl)-2-benzimidazolamineHomo sapiens (human)IC5020.000010
1-(4-nitrophenyl)sulfonyl-2-benzimidazolamineHomo sapiens (human)IC5020.000010
CID 3192987Homo sapiens (human)IC508.569510
N-[3-[(3-chlorophenyl)sulfamoyl]-4-methylphenyl]-3-(4-nitrophenyl)-3-oxopropanamideHomo sapiens (human)IC507.046010
N-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-2-quinolinecarboxamideHomo sapiens (human)IC507.411010
[4-[(2-chlorophenyl)methylsulfonyl]-3-nitrophenyl]-[4-(2-pyridinyl)-1-piperazinyl]methanoneHomo sapiens (human)IC503.669820
N-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-4-oxo-1-benzopyran-2-carboxamideHomo sapiens (human)IC509.681010
1-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)-2-[(6-methyl-2-nitro-3-pyridinyl)oxy]ethanoneHomo sapiens (human)IC505.779010
4-(9-acridinylamino)-1,5-dimethyl-2-phenyl-3-pyrazoloneHomo sapiens (human)IC5020.000010
4-chloro-N-[3-(N-methylanilino)-1,4-dioxo-2-naphthalenyl]benzamideHomo sapiens (human)IC505.147510
[4-(3-chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(2-pyridinyl)-1-piperazinyl]methanoneHomo sapiens (human)IC503.072520
garcinone eHomo sapiens (human)IC5020.000010
[4-(2-chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(phenylmethyl)-1-piperazinyl]methanoneHomo sapiens (human)IC505.586220
[9-(benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanoneHomo sapiens (human)IC5014.727510
dafadine CHomo sapiens (human)IC509.143510
2-(2,4-dimethoxyphenyl)-5-methyl-4-[[4-(4-quinazolinyl)-1-piperazinyl]methyl]oxazoleHomo sapiens (human)IC506.958010
N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,5-dimethyl-3-pyrazolecarboxamideHomo sapiens (human)IC500.812220
N-[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,5-dimethyl-3-pyrazolecarboxamideHomo sapiens (human)IC500.079310
1-(4-methoxyphenyl)sulfonyl-2-benzimidazolamineHomo sapiens (human)IC5020.000010
5,6-dimethyl-1-(4-methylphenyl)sulfonyl-2-benzimidazolamineHomo sapiens (human)IC5020.000020