Page last updated: 2024-12-10

7-deoxy-13-dihydroadriamycinone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

7-deoxy-13-dihydroadriamycinone: a metabolite of epidoxorubicin [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3081104
MeSH IDM0201966

Synonyms (13)

Synonym
7-deoxydoxorubicinolone
7-deoxy-13-dihydroadriamycinone
5,12-naphthacenedione, 8-(1,2-dihydroxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-
116455-20-0
8-(1,2-dihydroxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
aglycone c
9-(1,2-dihydroxyethyl)-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7h-tetracene-5,12-dione
FT-0665798
J-012035
8-(1,2-dihydroxyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7h-tet racene-5,12-dione
7-deoxy doxorubicinol aglycone
8-(1,2-dihydroxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
DTXSID50863400

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" Pharmacokinetic studies between SB and SAB showed modest differences."( Isoflavone pharmacokinetics and metabolism after consumption of a standardized soy and soy-almond bread in men with asymptomatic prostate cancer.
Ahn-Jarvis, JH; Clinton, SK; Cruz-Cano, R; Grainger, EM; Lee, ML; Lesinski, GB; Riedl, KM; Schwartz, SJ; Vodovotz, Y; Young, GS, 2015
)
0.42

Bioavailability

ExcerptReferenceRelevance
" The primary objective was to investigate isoflavone bioavailability and metabolite profile."( Isoflavone pharmacokinetics and metabolism after consumption of a standardized soy and soy-almond bread in men with asymptomatic prostate cancer.
Ahn-Jarvis, JH; Clinton, SK; Cruz-Cano, R; Grainger, EM; Lee, ML; Lesinski, GB; Riedl, KM; Schwartz, SJ; Vodovotz, Y; Young, GS, 2015
)
0.42

Dosage Studied

ExcerptRelevanceReference
" Therefore, measuring the plasma concentration of doxorubicin and its metabolites is important to study the dosing regimen of doxorubicin."( Rapid and sensitive method for measuring the plasma concentration of doxorubicin and its metabolites.
Kawanishi, T; Nanjo, K; Okuda, H; Sakai-Kato, K, 2012
)
0.38
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (17.65)18.2507
2000's7 (41.18)29.6817
2010's6 (35.29)24.3611
2020's1 (5.88)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.42

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.42 (24.57)
Research Supply Index3.18 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.42)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (4.55%)5.53%
Reviews2 (9.09%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other19 (86.36%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]