cd 3 color developer

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

CD 3 color developer: used in film laboratories; causes contact dermatitis & lichenoid reactions; RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	66693
CHEMBL ID	580441
SCHEMBL ID	2157605
MeSH ID	M0122329

Synonyms (42)

Synonym
AKOS005431280
92-09-1
4-amino-n-ethyl-n-(.beta.-methylsulfonamidoethyl)-m-toluidinephosphate
methanesulfonamide, n-[2-[(4-amino-3-methylphenyl)ethylamino]ethyl]-
methanesulfonamide, n-[2-(4-amino-n-ethyl-m-toluidino)ethyl]-
n-[2-(4-amino-n-ethyl-m-toluidino)ethyl]methanesulfonamide
4-amino-n-ethyl-m-(.beta.-methanesulfonamidoethyl)-m-toluidine
m-toluidine, 4-amino-n-ethyl-n-(.beta.-methanesulfonamidethyl)-
nsc517164
nsc-517164
m-toluidine, 4-amino-n-ethyl-n-(beta-methanesulfonamidethyl)-
nsc 517164
methanesulfonamide, n-(2-(4-amino-n-ethyl-m-toluidino)ethyl)-
m-toluidine, 4-amino-n-ethyl-n-(beta-methanesulfonamidoethyl)-
n-(2-((4-amino-m-tolyl)ethylamino)ethyl)methanesulphonamide
methanesulfonamide, n-(2-((4-amino-3-methylphenyl)ethylamino)ethyl)-
cd 3 color developer
n-(2-(4-amino-n-ethyl-m-toluidino)ethyl)methanesulfonamide
4-amino-n-ethyl-m-(beta-methanesulfonamidoethyl)-m-toluidine
einecs 202-124-2
4-amino-n-ethyl-n-(beta-methanesulfonamidoethyl)-m-toluidine
STK396654
n-{2-[(4-amino-3-methylphenyl)(ethyl)amino]ethyl}methanesulfonamide
n-[2-(4-amino-n-ethyl-3-methylanilino)ethyl]methanesulfonamide
unii-6vov6v71vo
6vov6v71vo ,
SCHEMBL2157605
CHEMBL580441
cd-3
4-amino-3-methyl-n-(beta-methanesulfonamidoethyl)-n-ethylaniline
DTXSID4043779
4-(n-ethyl-n-2-methanesulfonylaminoethyl)-2-methylphenylenediamine
n-(2-((4-amino-3-methylphenyl)(ethyl)amino)ethyl)methanesulfonamide
4-amino-3-methyl-n-ethyl-n-(.beta.-(methanesulfonamido)ethyl)aniline
3-methyl-4-amino-n,n-(ethyl-.beta.-mesylaminoethyl)-aniline
4-amino-n-ethyl-n-(.beta.-methanesulfonamidoethyl)-m-toluidine
4-amino-3-methyl-n-ethyl-n-(.beta.-methylsulfonamidoethyl)aniline
4-amino-3-methyl-n-ethyl-n-(2-methanesulfonamidoethyl)aniline
n-[2-[(4-amino-m-tolyl)ethylamino]ethyl]methanesulphonamide
BCP10485
Q27265600
STARBLD0000853

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay ID	Title	Year	Journal	Article
AID1794808	Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).	2014	Journal of biomolecular screening, Jul, Volume: 19, Issue:6	A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808	Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (14)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	7 (50.00)	18.7374
1990's	4 (28.57)	18.2507
2000's	1 (7.14)	29.6817
2010's	1 (7.14)	24.3611
2020's	1 (7.14)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.45

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	11.45 (24.57)
Research Supply Index	2.83 (2.92)
Research Growth Index	4.29 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (11.45)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	4 (25.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	12 (75.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
toluene methylbenzene : Any alkylbenzene that is benzene substituted with one or more methyl groups.	3.37	7	methylbenzene; toluenes; volatile organic compound	cholinergic antagonist; fuel additive; neurotoxin; non-polar solvent
anthralin Anthralin: An anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.. anthralin : An anthracene compound derived by the substitution of -OH groups for hydrogen at C-1 and C-8, and with an oxo group at C-9.	1.97	1	anthracenes	antipsoriatic
dimaprit Dimaprit: A histamine H2 receptor agonist that is often used to study the activity of histamine and its receptors.	2.37	2	imidothiocarbamic ester
n-methyl-4-aminophenol 4-methylaminophenol : The phenol that is the N-methyl derivative of 4-aminophenol.	2.37	2	phenols	allergen
n,n-diethyl 4-phenylenediamine N,N-diethyl 4-phenylenediamine: RN given refers to parent cpd	1.96	1
n-isopropyl-n-phenyl-4-phenylenediamine N-isopropyl-N-phenyl-4-phenylenediamine: RN given refers to parent cpd; structure in sixth source	1.96	1
isothiuronium Isothiuronium: An undecenyl THIOUREA which may have topical anti-inflammatory activity.	2.37	2
butantrone [no description available]	1.97	1
3-methyl-n,n-diethyl-p-phenylenediamine 3-methyl-N,N-diethyl-p-phenylenediamine: RN given refers to parent cpd; structure	3.58	9
4-amino-n-ethyl-n-(beta-hydroxy-ethyl)-m-toluidine 4-amino-N-ethyl-N-(beta-hydroxy-ethyl)-m-toluidine: causes allergic contact dermatitis	3.37	7
nordimaprit nordimaprit: effective agonist in the inhibition of lymphocyte activation	2.37	2

Condition	Relationship Strength	Studies
Plasmodium falciparum Malaria [description not available]	2.1	1
Malaria, Falciparum Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.	2.1	1
Licheniform Eruptions [description not available]	2.38	2
Lichen Ruber Planus [description not available]	2.88	4
Dermatitis, Occupational A recurrent contact dermatitis caused by substances found in the work place.	3.07	5
Lichen Planus An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a saw-tooth pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.	2.88	4
Contact Dermatitis [description not available]	3.06	5
Dermatitis, Contact A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.	3.06	5
Eczema, Atopic [description not available]	1.96	1
Diseases, Occupational [description not available]	2.37	2
Dermatitis, Atopic A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.	1.96	1
Allergic Contact Dermatitis [description not available]	2.68	3
Hand Dermatosis [description not available]	2.39	2
Hand Dermatoses Skin diseases involving the HANDS.	2.39	2
Dermatitis, Allergic Contact A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.	2.68	3
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2	1
Anasarca [description not available]	1.97	1
Edema Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.	1.97	1
Erythema Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.	1.97	1

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