Pentachlorothiophenol is a sulfur-containing organic compound with the formula C6Cl5SH. It is a white to yellowish solid. Pentachlorothiophenol is a useful building block in organic synthesis. For example, it can be used to prepare thioethers, sulfides, and disulfides. It can also be used to synthesize other sulfur-containing heterocycles. Pentachlorothiophenol is a potent inhibitor of the enzyme glutathione S-transferase. Glutathione S-transferase is an enzyme that plays an important role in detoxification. Pentachlorothiophenol is also a known fungicide. This compound has been used to study the reaction mechanisms of certain organic reactions.'
| ID Source | ID |
|---|---|
| PubMed CID | 8620 |
| SCHEMBL ID | 48512 |
| MeSH ID | M0062445 |
| Synonym |
|---|
| wln: shr bg cg dg eg fg |
| 133-49-3 |
| pentachlorothiophenol |
| pentachlorobenzenethiol |
| nsc-5578 |
| pentachlorthiofenol |
| nsc5578 |
| benzenethiol, pentachloro- |
| usaf b-51 |
| rpa 6 |
| 2,3,4,5,6-pentachlorobenzenethiol |
| pentachloro-benzenethiol |
| nsc 5578 |
| einecs 205-107-8 |
| pctp |
| ai3-23118 |
| hsdb 6124 |
| pentachlorthiofenol [czech] |
| brn 1108638 |
| AC-11106 |
| P0312 |
| A806624 |
| AKOS005463160 |
| 2,3,4,5,6-pentachloro-benzenethiol |
| pentachloro thiophenol |
| STK530289 |
| 92a1z48vjb , |
| 4-06-00-01642 (beilstein handbook reference) |
| unii-92a1z48vjb |
| benzenethiol, 2,3,4,5,6-pentachloro- |
| FT-0631773 |
| SCHEMBL48512 |
| BBL028077 |
| pentachlorothiophenol [hsdb] |
| DTXSID3044540 |
| Q-201540 |
| renacit 7 (salt/mix) |
| akrochem peptizer ptp |
| pentachloro benzenethiol |
| pentachlorthiophenol |
| 2,3,4,5,6-pentachlorobenzenethiol # |
| mfcd00059146 |
| pentachlorothiophenol, analytical standard |
| CS-0204835 |
| pentachlorobenzene-1-thiol |
| VS-08658 |
| Q1754155 |
| D91942 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " The liver HCB concentration at 24 hr after dosing was higher in male rats than in female rats but decreased faster thereafter." | ( Sex-related difference in hepatic glutathione conjugation of hexachlorobenzene in the rat. Charbonneau, M; D'Amour, M, 1992) | 0.28 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (33.04) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||