Compounds > succinic anhydride
Page last updated: 2024-09-21

succinic anhydride

Cross-References

ID SourceID
PubMed CID7922
CHEMBL ID1370164
CHEBI ID36595
SCHEMBL ID16123
MeSH IDM0099681

Synonyms (93)

Synonym
CHEBI:36595 ,
oxolane-2,5-dione
tetrahydro-2,5-furandione
bernsteinsaeureanhydrid
2,5-dioxotetrahydrofuran
tetrahydro-furan-2,5-dione
succinyl anhydride
bernsteinsaure-anhydrid
succinyl oxide
butanedioic anhydride
108-30-5
wln: t5vovtj
2,5-diketotetrahydrofuran
succinic anhydride
2, dihydro-
succinic acid anhydride
nci-c55696
nsc8518
dihydro-2,5-furandione
nsc-8518
tetrahydro-2,5-dioxofuran
succinic anhydride treated bsa
dihydro-furan-2,5-dione
2,5-furandione, dihydro-
butanedioic acid,anhydride succinic anhydride
inchi=1/c4h4o3/c5-3-1-2-4(6)7-3/h1-2h
dihydrofuran-2,5-dione
NCGC00091291-01
ccris 2386
bernsteinsaure-anhydrid [german]
hsdb 792
nsc 8518
brn 0108441
dihydro-2,5-diketotetrahydrofuran
rikacid sa
succinyloxide
einecs 203-570-0
ai3-52664
succinic anhydride, 97%
succinic anhydride, >=99% (gc)
smr001372026
MLS002454448
FT-0652573
S0107
AKOS000121191
A801840
NCGC00091291-02
6rf4o17z8j ,
ec 203-570-0
unii-6rf4o17z8j
5-17-11-00006 (beilstein handbook reference)
C19524
HMS3039B10
dtxcid701287
cas-108-30-5
tox21_201179
dtxsid7021287 ,
NCGC00258731-01
68412-02-2
einecs 270-161-1
BP-13070
FT-0637061
succinic anhydride [inci]
succinic anhydride [hsdb]
succinic anhydride [mi]
succinic anhydride [iarc]
SCHEMBL16123
butanedioic acid anhydride
tetrahydrofuran-2,5-dione
2,5(3h,4h)-furandione
STR01303
CHEMBL1370164
CS-0011581
mfcd00005525
J-002088
F1908-0090
succinic anhydride, saj first grade, >=99.0%
succinic anhydride, puriss., >=99.0% (nt)
succinic anhydride, >=97.0% (nt)
D78120
tetrahydro-2, 5-dioxofuran
butanedioic acid,anhydride succinic anhydride
dihydro-2, 5-furandione
Z57127506
HY-79369
Q417847
STL194303
oxolan-2,5-dione
EN300-18021
succinicanhydride-13c4
bernsteinsaureanhydrid
succinic anhydride (iarc)
tetrahydro-2,5-furandione(national library of medicine, sis; chemidplus record for succinic anhydride (108-30-5) available from, as of july 21, 2005: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp)

Effects

ExcerptReference
"Succinic anhydride has been frequently used in adhesives and sealant chemicals for a long time, and here, it is evaluated for dye removal performance."( Akhtar, MS; Aljuwayid, AM; Alothman, ZA; Aziz, T; Chinnam, S; Farid, A; Habila, MA; Haq, F; Kiran, M; Wani, AW, 2023)

Drug Classes (2)

ClassDescription
cyclic dicarboxylic anhydrideAn acid anhydride derived by loss of water between two carboxylic groups in the same molecule so as to close a ring.
tetrahydrofurandione
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (4)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
RAR-related orphan receptor gammaMus musculus (house mouse)Potency0.00690.006038.004119,952.5996AID1159521
thyroid stimulating hormone receptorHomo sapiens (human)Potency1.25890.001318.074339.8107AID926; AID938
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency0.06310.000214.376460.0339AID588532
gemininHomo sapiens (human)Potency0.74200.004611.374133.4983AID624296; AID624297
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (13)

Assay IDTitleYearJournalArticle
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (248)

TimeframeStudies, This Drug (%)All Drugs %
pre-199029 (11.69)18.7374
1990's32 (12.90)18.2507
2000's48 (19.35)29.6817
2010's88 (35.48)24.3611
2020's51 (20.56)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (0.39%)5.53%
Reviews3 (1.16%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other254 (98.45%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
quercetin[no description available]medium107-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger
mannans[no description available]medium20
1-anilino-8-naphthalenesulfonate[no description available]medium40aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
pectins[no description available]medium20D-galactopyranuronic acid
maltodextrin[no description available]medium10
chitosan[no description available]medium150
mannose[no description available]medium10D-aldohexose;
D-mannose;
mannopyranose		metabolite
curcumin[no description available]medium50aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger
tannins[no description available]medium10
cellulose[no description available]medium180glycoside
resveratrol[no description available]medium10resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger
sizofiran[no description available]medium10
sodium borate[no description available]medium10
hydroxyl radical[no description available]medium10oxygen hydride;
oxygen radical;
reactive oxygen species
caprolactone[no description available]medium20epsilon-lactone
nitrates[no description available]medium10monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
d-alpha tocopherol[no description available]medium10alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
phthalic anhydride[no description available]medium402-benzofurans;
cyclic dicarboxylic anhydride		allergen
tryptophan[no description available]medium20erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
amylopectin[no description available]medium50
potassium carbonate[no description available]medium10carbonate salt;
potassium salt		catalyst;
fertilizer;
flame retardant
dimethyl sulfoxide[no description available]medium30sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
fructans[no description available]medium10
carvacrol[no description available]medium10botanical anti-fungal agent;
p-menthane monoterpenoid;
phenols		agrochemical;
antimicrobial agent;
flavouring agent;
TRPA1 channel agonist;
volatile oil component
nonenyl succinic anhydride[no description available]medium20
ferulic acid[no description available]medium20ferulic acidsanti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
MALDI matrix material;
plant metabolite
beta carotene[no description available]medium10carotenoid beta-end derivative;
cyclic carotene		antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A
betadex[no description available]medium10cyclodextrin
deoxycholic acid[no description available]medium10bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human blood serum metabolite
caloreen[no description available]medium30
octenyl succinate[no description available]medium20
naringin[no description available]medium10(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
neohesperidoside		anti-inflammatory agent;
antineoplastic agent;
metabolite
sucrose[no description available]medium10glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
2,3-dimethylmaleic anhydride[no description available]medium20butenolide
maleic anhydride[no description available]medium90cyclic dicarboxylic anhydride;
furans		allergen
daunorubicin[no description available]medium10aminoglycoside antibiotic;
anthracycline;
p-quinones;
tetracenequinones		antineoplastic agent;
bacterial metabolite
domperidone[no description available]medium10benzimidazoles;
heteroarylpiperidine		antiemetic;
dopaminergic antagonist
hydrogen[no description available]medium20elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
1-allyl-3-methylimidazolium[no description available]medium10
muramidase[no description available]medium20
sepharose[no description available]medium10
isosorbide[no description available]medium10organic molecular entity
1,4-butanediol[no description available]medium10butanediol;
glycol		neurotoxin;
prodrug;
protic solvent
docetaxel anhydrous[no description available]medium10secondary alpha-hydroxy ketone;
tetracyclic diterpenoid		antimalarial;
antineoplastic agent;
photosensitizing agent
dicyclohexylcarbodiimide[no description available]medium10carbodiimideATP synthase inhibitor;
cross-linking reagent;
peptide coupling reagent
2-naphthol[no description available]medium10naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
alpha-aminopyridine[no description available]medium20
sodium hydroxide[no description available]medium30alkali metal hydroxide
citric acid, anhydrous[no description available]medium30tricarboxylic acidantimicrobial agent;
chelator;
food acidity regulator;
fundamental metabolite
glycerol[no description available]medium20alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
cyclosporine[no description available]medium10
methane[no description available]medium10alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound		bacterial metabolite;
fossil fuel;
greenhouse gas
lutein[no description available]medium10carotenolfood colouring;
plant metabolite
fluorexon[no description available]medium10xanthene dyefluorochrome
folic acid[no description available]medium10folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
protoporphyrin ix[no description available]medium10
erythrosine[no description available]medium10
4-butyrolactone[no description available]medium30butan-4-olidemetabolite;
neurotoxin
ruthenium[no description available]medium10iron group element atom;
platinum group metal atom
ethylmaleimide[no description available]medium10maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
deoxycytidine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
paclitaxel[no description available]medium10taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
gemcitabine[no description available]medium10organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
environmental contaminant;
immunosuppressive agent;
photosensitizing agent;
prodrug;
radiosensitizing agent;
xenobiotic
cadmium[no description available]medium30cadmium molecular entity;
zinc group element atom
diethylene glycol[no description available]medium10hydroxyether
isoprene[no description available]medium10alkadiene;
hemiterpene;
volatile organic compound		plant metabolite
carvone[no description available]medium10botanical anti-fungal agent;
carvones		allergen
phosphoryl chloride[no description available]medium10phosphorus coordination entity
acetic anhydride[no description available]medium130acyclic carboxylic anhydridemetabolite;
reagent
trimetaphosphoric acid[no description available]medium10cyclic phosphorus acid anhydride;
inorganic heterocyclic compound;
phosphorus oxoacid
chloramphenicol[no description available]medium10C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
spermidine[no description available]medium10polyazaalkane;
triamine		autophagy inducer;
fundamental metabolite;
geroprotector
succinic acid[no description available]medium40alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent
timolol[no description available]medium10timololanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
triphosphoric acid[no description available]medium10acyclic phosphorus acid anhydride;
phosphorus oxoacid
glucuronic acid[no description available]medium20D-glucuronic acidalgal metabolite
phencyclidine[no description available]medium10benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
fenofibrate[no description available]medium10aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
ethyldimethylaminopropyl carbodiimide[no description available]medium10
2-mercaptonicotinic acid[no description available]medium10
aminopropylsilane[no description available]medium10
glutaral[no description available]medium20dialdehydecross-linking reagent;
disinfectant;
fixative
silicon[no description available]medium10carbon group element atom;
metalloid atom;
nonmetal atom
sulfamethoxazole[no description available]medium10isoxazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
antiinfective agent;
antimicrobial agent;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
epitope;
P450 inhibitor;
xenobiotic
azoxymethane[no description available]medium10
stearic acid[no description available]medium10long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite
lithium chloride[no description available]medium10inorganic chloride;
lithium salt		antimanic drug;
geroprotector
urea[no description available]medium20isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
rivastigmine[no description available]medium10carbamate ester;
tertiary amino compound		cholinergic drug;
EC 3.1.1.8 (cholinesterase) inhibitor;
neuroprotective agent
2-methoxyestradiol[no description available]medium1017beta-hydroxy steroid;
3-hydroxy steroid		angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite
divinyl sulfone[no description available]medium10sulfonecross-linking reagent
bisbenzimidazole[no description available]medium10bibenzimidazole;
N-methylpiperazine		anthelminthic drug;
fluorochrome
aspartic acid[no description available]medium10aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
ammonium hydroxide[no description available]medium10azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
asparagine[no description available]medium10amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
epidermal growth factor[no description available]medium10
bromosuccinimide[no description available]medium20dicarboximide;
organobromine compound;
pyrrolidinone		reagent
chromium[no description available]medium10chromium cation;
monoatomic hexacation
chromium[no description available]medium10chromium group element atom;
metal allergen		micronutrient
caseins[no description available]medium30
ethylenediamine[no description available]medium20alkane-alpha,omega-diamineGABA agonist
lysine[no description available]medium150aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
methylcellulose[no description available]medium10
lead[no description available]medium20carbon group element atom;
elemental lead;
metal atom		neurotoxin
cysteine[no description available]medium30cysteiniumfundamental metabolite
acrylamide[no description available]medium20acrylamides;
N-acylammonia;
primary carboxamide		alkylating agent;
carcinogenic agent;
Maillard reaction product;
mutagen;
neurotoxin
propionic anhydride[no description available]medium10
camptothecin[no description available]medium20delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
lignin[no description available]medium20
dinitrofluorobenzene[no description available]medium10C-nitro compound;
organofluorine compound		agrochemical;
allergen;
chromatographic reagent;
EC 2.7.3.2 (creatine kinase) inhibitor;
protein-sequencing agent;
spectrophotometric reagent
hydroxyproline[no description available]medium104-hydroxyproline;
L-alpha-amino acid zwitterion		human metabolite;
mouse metabolite;
plant metabolite
genipin[no description available]medium10iridoid monoterpenoidanti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cross-linking reagent;
hepatotoxic agent;
uncoupling protein inhibitor
iridoids[no description available]medium10
pyridine[no description available]medium10azaarene;
mancude organic heteromonocyclic parent;
monocyclic heteroarene;
pyridines		environmental contaminant;
NMR chemical shift reference compound
ovalbumin[no description available]medium20
dicofol[no description available]medium10monochlorobenzenes;
organochlorine acaricide;
tertiary alcohol
phenylisothiocyanate[no description available]medium20isothiocyanateallergen;
reagent
peroxyformic acid[no description available]medium30
pyrrolidonecarboxylic acid[no description available]medium205-oxoproline;
L-proline derivative;
non-proteinogenic L-alpha-amino acid		algal metabolite
bisphenol a[no description available]medium10bisphenolendocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen
nsc 83265[no description available]medium10benzenoid aromatic compound
limestone[no description available]medium10calcium salt;
carbonate salt;
inorganic calcium salt;
one-carbon compound		antacid;
fertilizer;
food colouring;
food firming agent
dicumyl peroxide[no description available]medium10
benzoyl peroxide[no description available]medium10carbonyl compound
3-(trimethoxysilyl)propylamine[no description available]medium10
galactose[no description available]medium10D-galactose;
galactopyranose		Escherichia coli metabolite;
mouse metabolite
boranes[no description available]medium10boranes;
mononuclear parent hydride
formaldehyde[no description available]medium10aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
4-hydroxy-2-hexenal[no description available]medium10fatty aldehyde
4-hydroxy-2-nonenal[no description available]medium104-hydroxynon-2-enal;
4-hydroxynonenal
deuterium[no description available]medium50dihydrogen
hydrazine[no description available]medium20azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
sulfadiazine[no description available]medium10pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
antiprotozoal drug;
coccidiostat;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
toluene[no description available]medium10methylbenzene;
toluenes;
volatile organic compound		cholinergic antagonist;
fuel additive;
neurotoxin;
non-polar solvent
1-methyl-3-ethylimidazolium[no description available]medium101-alkyl-3-methylimidazolium
alanylalanine[no description available]medium10dipeptide
ristocetin[no description available]medium10glycopeptide;
heterodetic cyclic peptide;
macrocycle;
tetrasaccharide derivative		antibacterial drug;
antimicrobial agent;
bacterial metabolite;
platelet-activating factor receptor agonist
histidine[no description available]medium20amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
chlorine[no description available]medium10halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
pituitrin[no description available]medium10
n-vinyl-2-pyrrolidinone[no description available]medium10pyrrolidin-2-ones
ciprofloxacin[no description available]medium10aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
ethylene dimethacrylate[no description available]medium10enoate esterallergen;
cross-linking reagent;
polymerisation monomer
ethylene glycol[no description available]medium10ethanediol;
glycol		metabolite;
mouse metabolite;
solvent;
toxin
formamide[no description available]medium10carboximidic acid;
formamides;
monocarboxylic acid amide;
one-carbon compound		solvent
aluminum[no description available]medium20boron group element atom;
elemental aluminium;
metal atom
nickel[no description available]medium20metal allergen;
nickel group element atom		epitope;
micronutrient
aconitic acid[no description available]medium10tricarboxylic acid
aconitic anhydride[no description available]medium10
n-succinyl-chitosan[no description available]medium10
diclofenac[no description available]medium10amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
1-monooleoyl-rac-glycerol[no description available]medium101-acylglycerol 18:1;
monooleoylglycerol		plant metabolite
polytrimethylene carbonate[no description available]medium10
mercury[no description available]medium10elemental mercury;
zinc group element atom		neurotoxin
arginyl-glycyl-aspartic acid[no description available]medium10oligopeptide
heme[no description available]medium10
agar[no description available]medium10
trifluoroacetic acid[no description available]medium10fluoroalkanoic acidhuman xenobiotic metabolite;
NMR chemical shift reference compound;
reagent
shellac[no description available]medium10
bitoscanate[no description available]medium10benzenes
malondialdehyde[no description available]medium10dialdehydebiomarker
1,2-cyclohexanedione[no description available]medium10cyclohexanedione
arginine[no description available]medium20arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
tiletamine hydrochloride[no description available]medium10
phenylglyoxal[no description available]medium20phenylacetaldehydes
egtazic acid[no description available]medium10diether;
tertiary amino compound;
tetracarboxylic acid		chelator
phosphatidylcholines[no description available]medium201,2-diacyl-sn-glycero-3-phosphocholine
cyanogen bromide[no description available]medium20
11-cis-retinal[no description available]medium10retinalchromophore;
human metabolite;
mouse metabolite
diazodiiodosulfanilic acid[no description available]medium10
guanidine[no description available]medium10carboxamidine;
guanidines;
one-carbon compound
acetamide[no description available]medium10acetamides;
carboximidic acid;
monocarboxylic acid amide;
N-acylammonia
cystine[no description available]medium10
methacrylamide[no description available]medium20acrylamides;
primary carboxamide
hydroxyethyl methacrylate[no description available]medium30enoate esterallergen;
polymerisation monomer
carboxyl radical[no description available]medium10carbon oxide;
organic radical anion		xenobiotic metabolite
bisphenol a-glycidyl methacrylate[no description available]medium20diarylmethane
triethylene glycol dimethacrylate[no description available]medium20
g(m1) ganglioside[no description available]medium10alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine;
sialotetraosylceramide
p-azobenzenearsonate[no description available]medium20
n,n-dimethyl-4-anisidine[no description available]medium10
serine[no description available]medium10L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
threonine[no description available]medium10amino acid zwitterion;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
threonine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
2-hydroxy-5-nitrobenzyl bromide[no description available]medium10
tetranitromethane[no description available]medium20organonitrogen compound
suprofen[no description available]medium10aromatic ketone;
monocarboxylic acid;
thiophenes		antirheumatic drug;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
n-acetylneuraminic acid[no description available]medium10N-acetylneuraminic acidsantioxidant;
bacterial metabolite;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
human metabolite;
mouse metabolite
pimagedine[no description available]medium10guanidines;
one-carbon compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 1.4.3.4 (monoamine oxidase) inhibitor
thymidine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
iodoacetic acid[no description available]medium10haloacetic acid;
organoiodine compound		alkylating agent
4-vinylpyridine[no description available]medium10
fluorescein-5-isothiocyanate[no description available]medium10fluorescein isothiocyanate
pentetic acid[no description available]medium10pentacarboxylic acidcopper chelator
sodium cyanate[no description available]medium10cyanate salt;
one-carbon compound
cyanates[no description available]medium10
neoandrographolide[no description available]medium10
glucose, (beta-d)-isomer[no description available]medium10D-glucopyranoseepitope;
mouse metabolite
andrographolide[no description available]medium10carbobicyclic compound;
gamma-lactone;
labdane diterpenoid;
primary alcohol;
secondary alcohol		anti-HIV agent;
anti-inflammatory drug;
antineoplastic agent;
metabolite
guanine[no description available]medium102-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
8-hydroxyguanine[no description available]medium10oxopurine
roxindole[no description available]medium10indolesalpha-adrenergic antagonist;
serotonergic drug
dinitrochlorobenzene[no description available]medium10C-nitro compound;
monochlorobenzenes		allergen;
epitope;
sensitiser
indomethacin[no description available]medium10aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
o-methylisourea[no description available]medium10
cardiovascular agents[no description available]medium10
acebutolol[no description available]medium10alpha-D-glucosyl-(1->4)-D-mannopyranose
3-maleimidobenzoyl n-hydroxysuccinimide[no description available]medium10
m-maleimidobenzoyl-n-hydroxysulfosuccinimide ester[no description available]medium10
tretinoin[no description available]medium10retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
farnesoic acid[no description available]medium10farnesoic acidanimal metabolite
farnesol[no description available]medium10farnesolplant metabolite
methacrylic acid[no description available]medium10alpha,beta-unsaturated monocarboxylic acid
methyl acetimidate[no description available]medium10
trinitrobenzenesulfonic acid[no description available]medium20arenesulfonic acid;
C-nitro compound		epitope;
explosive;
reagent
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid[no description available]medium10stilbenoid
phosphoric acid[no description available]medium10phosphoric acidsalgal metabolite;
fertilizer;
human metabolite;
NMR chemical shift reference compound;
solvent
dihydrotestosterone[no description available]medium1017beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
3-methylthiopropionate[no description available]medium10thia fatty acidphytotoxin
biotin[no description available]medium10biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
valinomycin[no description available]medium10cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore
nigericin[no description available]medium10polycyclic etherantibacterial agent;
antimicrobial agent;
bacterial metabolite;
potassium ionophore
potassium iodide[no description available]medium10potassium saltexpectorant;
radical scavenger
bilirubin[no description available]medium10biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
lactic acid[no description available]medium102-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
gamma-aminobutyric acid[no description available]medium10amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule
pyruvic acid[no description available]medium102-oxo monocarboxylic acidcofactor;
fundamental metabolite
sodium dodecyl sulfate[no description available]medium10organic sodium saltdetergent;
protein denaturant
alpha-chymotrypsin[no description available]medium10
metaperiodate[no description available]medium10iodine oxoacid
permanganate[no description available]medium10manganese oxoacid
hypochlorous acid[no description available]medium10chlorine oxoacid;
reactive oxygen species		EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite
transferrin[no description available]medium10
manganese[no description available]medium10elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
hydrogen carbonate[no description available]medium10carbon oxoanioncofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
metaperiodate[no description available]medium10iodine oxoanion;
monovalent inorganic anion
diethyl pyrocarbonate[no description available]medium20acyclic carboxylic anhydride
thyroxine[no description available]medium102-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
dithioerythritol[no description available]medium101,4-dimercaptobutane-2,3-diolreducing agent
dithiobis(succinimidylpropionate)[no description available]medium10
cantharidin[no description available]low00cyclic dicarboxylic anhydride;
monoterpenoid		EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
herbicide
1,8-naphthalenedicarboxylic acid anhydride[no description available]low00cyclic dicarboxylic anhydride
glutaric anhydride[no description available]low00cyclic dicarboxylic anhydride;
oxanes
tetrachlorophthalic anhydride[no description available]low00cyclic dicarboxylic anhydride;
tetrachlorobenzene		allergen;
cross-linking reagent
trimellitic anhydride[no description available]low002-benzofurans;
cyclic dicarboxylic anhydride;
dioxo monocarboxylic acid		allergen;
epitope;
hapten
tetrabromophthalic anhydride[no description available]low002-benzofurans;
cyclic dicarboxylic anhydride
cornexistin[no description available]low00cyclic dicarboxylic anhydride;
organic heterobicyclic compound;
secondary alpha-hydroxy ketone		herbicide;
metabolite
keto-pantoyllactone[no description available]low00tetrahydrofurandione
ConditionIndicatedRelationship StrengthStudiesTrials
Acute Kidney Failure0low10
Acute Kidney Injury0low10
Acute Kidney Insufficiency0low10
Acute Myelogenous Leukemia0low10
Acute Myeloid Leukemia0low10
Acute Myeloid Leukemia with Maturation0low10
Acute Myeloid Leukemia without Maturation0low10
Acute Renal Failure0low10
Acute Renal Injury0low10
Acute Renal Insufficiency0low10
Aging0low10
ANLL0low10
Arteriosclerosis0low10
Asthma0low10
Asthma, Bronchial0low10
Benign Neoplasms0low20
Bleeding0low20
Blood Clot0low10
Body Weight0low10
Bronchial Asthma0low10
Cancer0low20
Cancer of Colon0low10
Cancer of Liver0low10
Cancer of Mouth0low10
Cancer of the Colon0low10
Cancer of the Liver0low10
Cancer of the Mouth0low10
Cancer, Hepatocellular0low10
Carcinoma, Epidermoid0low10
Carcinoma, Hepatocellular0low10
Carcinoma, Planocellular0low10
Carcinoma, Squamous0low10
Carcinoma, Squamous Cell0low10
Colon Cancer0low10
Colon Neoplasms0low10
Colonic Cancer0low10
Colonic Neoplasms0low10
Cushing Syndrome0low10
Cushing's Syndrome0low10
Dehydration0low10
Disease Models, Animal0low10
Experimental Neoplasms0low20
Extravascular Hemolysis0low50
Granuloma0low10
Granulomas0low10
Haemolysis0low50
Hemolysis0low50
Hemorrhage0low20
Hepatic Cancer0low10
Hepatic Neoplasms0low10
Hepatocellular Cancer0low10
Hepatocellular Carcinoma0low10
Hepatoma0low10
Hypercortisolism0low10
Infection, Wound0low10
Inflammation0low10
Innate Inflammatory Response0low10
Intravascular Hemolysis0low50
Kidney Failure, Acute0low10
Kidney Insufficiency, Acute0low10
Leukemia, Acute Myelogenous0low10
Leukemia, Acute Myeloid0low10
Leukemia, Myeloblastic, Acute0low10
Leukemia, Myelocytic, Acute0low10
Leukemia, Myelogenous, Acute0low10
Leukemia, Myeloid, Acute0low10
Leukemia, Myeloid, Acute, M10low10
Leukemia, Myeloid, Acute, M20low10
Leukemia, Nonlymphoblastic, Acute0low10
Leukemia, Nonlymphocytic, Acute0low10
Liver Cancer0low10
Liver Cancer, Adult0low10
Liver Cell Carcinoma0low10
Liver Cell Carcinoma, Adult0low10
Liver Neoplasms0low10
Malignancy0low20
Malignant Neoplasms0low20
Mouth Cancer0low10
Mouth Neoplasms0low10
Myeloblastic Leukemia, Acute0low10
Myelocytic Leukemia, Acute0low10
Myelogenous Leukemia, Acute0low10
Myeloid Leukemia, Acute0low10
Myeloid Leukemia, Acute, M10low10
Myeloid Leukemia, Acute, M20low10
Neoplasia0low20
Neoplasm0low20
Neoplasms0low20
Neoplasms, Benign0low20
Neoplasms, Colonic0low10
Neoplasms, Experimental0low20
Neoplasms, Hepatic0low10
Neoplasms, Liver0low10
Neoplasms, Mouth0low10
Neoplasms, Oral0low10
Nonlymphoblastic Leukemia, Acute0low10
Nonlymphocytic Leukemia, Acute0low10
Oral Cancer0low10
Oral Neoplasms0low10
Renal Failure, Acute0low10
Renal Insufficiency, Acute0low10
Schistosoma mansoni Infection0low10
Schistosomiasis mansoni0low10
Schistosomiasis, Intestinal0low10
Sensitivity and Specificity0low40
Squamous Cell Carcinoma0low10
Thrombosis0low10
Thrombus0low10
Tumors0low20
Viral Diseases0low10
Viral Infections0low10
Virus Diseases0low10
Virus Infections0low10
Water Stress0low10
Wound Infection0low10

Research Highlights

Safety/Toxicity (1)

ArticleYear
Facile one-pot preparation, surface functionalization, and toxicity assay of APTS-coated iron oxide nanoparticles.
Nanotechnology, Mar-16, Volume: 23, Issue: 10		2012
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (4)

ArticleYear
Application of Curcumin Emulsion Carrier from Ultrasonic-Assisted Prepared Octenyl Succinic Anhydride Rice Starch.
Molecules (Basel, Switzerland), Oct-17, Volume: 27, Issue: 20		2022
A novel approach of encapsulating curcumin and succinylated derivative in mannosylated-chitosan nanoparticles.
Carbohydrate polymers, Dec-01, Volume: 297		2022
Recent advances of octenyl succinic anhydride modified polysaccharides as wall materials for nano-encapsulation of hydrophobic bioactive compounds.
Journal of the science of food and agriculture, Volume: 102, Issue: 14		2022
Cellulose-based film modified by succinic anhydride for the controlled release of domperidone.
Journal of biomaterials science. Polymer edition, Volume: 29, Issue: 11		2018
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (3)

ArticleYear
Removal of cadmium(II) from aqueous solutions by chemically modified maize straw.
Carbohydrate polymers, Jan-22, Volume: 115		2015
Body distributioin of RGD-mediated liposome in brain-targeting drug delivery.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, Volume: 127, Issue: 9		2007
Clostridium difficile recombinant toxin A repeating units as a carrier protein for conjugate vaccines: studies of pneumococcal type 14, Escherichia coli K1, and Shigella flexneri type 2a polysaccharides in mice.
Infection and immunity, Volume: 68, Issue: 4		2000
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]