Compounds > zwittergent 3-12
Page last updated: 2024-09-24

zwittergent 3-12

Description

zwittergent 3-12: zwitterionic detergent [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

lauryl sulfobetaine : An ammonium betaine in which the ammonium nitrogen is substituted by dodecyl, 3-sulfatopropyl and two methyl groups. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID84703
CHEMBL ID1235854
CHEBI ID75303
SCHEMBL ID60617
MeSH IDM0106842

Synonyms (82)

Synonym
chebi:75303 ,
CHEMBL1235854
AKOS015839847
n-dodecyl-n,n-dimethyl-3-ammonio-1-propanesulfonate
3-(lauryldimethylammonio)propanesulfonate
lauryl sulfobetaine
dodecyldimethyl(3-sulphonatopropyl)ammonium
3-(dodecyldimethylammonio)propanesulfonate
zwittergent 3-12
lauryl sultaine
14933-08-5
3-[dodecyl(dimethyl)ammonio]propane-1-sulfonate
3-(dodecyldimethylammonio)propane-1-sulfonate
dodecyldimethyl(3-sulfopropyl)ammonium hydroxide inner salt
D2332
3-(lauryldimethylammonio)propane-1-sulfonate
lauryldimethyl(3-sulfopropyl)ammonium hydroxide inner salt
3-[dodecyl(dimethyl)azaniumyl]propane-1-sulfonate
n-dodecyl-n,n-dimethyl-3-amino-1-propane sulfonate
tm 3-12
unii-r6p3kw3e8u
1-dodecanaminium, n,n-dimethyl-n-(3-sulfopropyl)-, hydroxide, inner salt
n-dodecyl-n,n-dimethylammonium-1-propane-3-sulfonate
n,n-dimethyl-n-(3-sulfopropyl)-1-dodecanaminium hydroxide, inner salt
1-dodecanaminium, n,n-dimethyl-n-(3-sulfopropyl)-, inner salt
sb12
bs-12
einecs 239-002-3
zwittergent
r6p3kw3e8u ,
68201-55-8
sulfobetaine 12
cas-14933-08-5
tox21_202807
dtxcid8029078
NCGC00260353-01
dtxsid6049222 ,
D3860
n,n-dimethyl-n-(3-sulfopropyl)-1-dodecanaminium hydroxide inner salt
dodecyl sulfobetaine
FT-0629530
3-(n,n-dimethyldodecylammonio)propanesulfonate
BP-30073
SCHEMBL60617
c17h37no3s
n-dodecyl-n,n-dimethylammonio-3-propanesulfonate
3-(n,n-dimethyl-n-laurylamino)propanesulfonic acid inner salt
3-(n,n-dimethyl-1-dodecylammonium)propanesulfonate
ammonium, dodecyldimethyl(3-sulfopropyl)-, hydroxide, inner salt
3-(n-dodecyl-n,n-dimethylammonium)propane-1-sulfonic acid inner salt
laurylpropylsulfobetaine
3-(n-dodecyl-n,n-dimethylammonio)-1-propanesulfonate
3-(dodecyldimethylammonio)-1-propanesulfonate
n-dodecyl-n,n-dimethyl-3-ammonio-1-propanesulphonate
.alpha.-(dodecyldimethylammonio)--propanesulfonate
3-(n-lauryl-n,n-dimethylamino)propanesulfonate inner salt
3-(dodecyldimethylammonio)propanesulfonate inner salt
ddaps
dodecyldimethyl(3-sulfopropyl)ammonium inner salt
lauryl sultaine [inci]
3-(n,n-dimethyl-n-dodecylammonio)propane-1-sulfonate
n-dodecylsulfobetaine
n-dodecyl-n,n-dimethyl-3-ammonium-1-propanesulfonate
3-(dimethyldodecylammonio)propane-1-sulfonate
dodecyldimethyl(3-sulfopropyl)ammonium hydroxide
mfcd00036909
3-(dodecyldimethylazaniumyl)propane-1-sulfonate
AS-75101
J-008579
zwittergent 3-12 detergent
Q27145205
3-(n,n-dimethyldodecylammonio)propane sulfonate
AMY22252
3-[dimethyl(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-pentacosadeuteriododecyl)azaniumyl]propane-1-sulfonate
D70364
SB83274
?n-dodecyl-n,n-dimethyl-3-ammonio-1-propanesulfonate
CS-0185823
HY-W127620
sulfobetaine-12
SY052089
M02487

Roles (1)

RoleDescription
detergentA surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
ammonium betaineAny neutral molecule having charge-separated forms with a quaternary ammonium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

zwittergent 3-12 is involved in 1 pathway(s), involving a total of 8 unique proteins and 8 unique compounds

PathwayProteinsCompounds
mitochondrial L-carnitine shuttle88

Protein Targets (5)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
RAR-related orphan receptor gammaMus musculus (house mouse)Potency31.01210.006038.004119,952.5996AID1159523
AR proteinHomo sapiens (human)Potency31.75590.000221.22318,912.5098AID1259243; AID1259247; AID743035; AID743042; AID743054; AID743063
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency11.83920.000214.376460.0339AID720691; AID720692
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency23.42410.001530.607315,848.9004AID1224841; AID1224848; AID1224849; AID1259401; AID1259403
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency26.67740.000323.4451159.6830AID743065; AID743067
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID537735Binding affinity to Candida albicans CaMdr1p expressed in yeast AD1-8u2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
AID537736Antifungal activity against yeast AD1-8u expressing Candida albicans CaCdr1p by agar disk diffusion assay2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
AID537734Antifungal activity against yeast AD1-8u expressing Candida albicans CaMdr1p by agar disk diffusion assay2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
AID537733Binding affinity to Candida albicans CaCdr1p expressed in yeast AD1-8u2010European journal of medicinal chemistry, Nov, Volume: 45, Issue:11
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (83)

TimeframeStudies, This Drug (%)All Drugs %
pre-199025 (30.12)18.7374
1990's16 (19.28)18.2507
2000's22 (26.51)29.6817
2010's14 (16.87)24.3611
2020's6 (7.23)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (1.20%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other82 (98.80%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
imidazole[no description available]medium10imidazole
oxyquinoline[no description available]medium10monohydroxyquinolineantibacterial agent;
antifungal agrochemical;
antiseptic drug;
iron chelator
verapamil[no description available]medium20aromatic ether;
nitrile;
polyether;
tertiary amino compound
carbonyl cyanide m-chlorophenyl hydrazone[no description available]medium10hydrazone;
monochlorobenzenes;
nitrile		antibacterial agent;
geroprotector;
ionophore
clotrimazole[no description available]medium10conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes		antiinfective agent;
environmental contaminant;
xenobiotic
disulfiram[no description available]medium10organic disulfide;
organosulfur acaricide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor
diuron[no description available]medium103-(3,4-substituted-phenyl)-1,1-dimethylurea;
dichlorobenzene		environmental contaminant;
mitochondrial respiratory-chain inhibitor;
photosystem-II inhibitor;
urea herbicide;
xenobiotic
fluconazole[no description available]medium10conazole antifungal drug;
difluorobenzene;
tertiary alcohol;
triazole antifungal drug		environmental contaminant;
P450 inhibitor;
xenobiotic
flucytosine[no description available]medium10aminopyrimidine;
nucleoside analogue;
organofluorine compound;
pyrimidine antifungal drug;
pyrimidone		prodrug
fluphenazine[no description available]medium10N-alkylpiperazine;
organofluorine compound;
phenothiazines		anticoronaviral agent;
dopaminergic antagonist;
phenothiazine antipsychotic drug
indomethacin[no description available]medium10aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
itraconazole[no description available]medium10piperazines
ketoconazole[no description available]medium10dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
miconazole[no description available]medium10dichlorobenzene;
ether;
imidazoles
mitoxantrone[no description available]medium10dihydroxyanthraquinoneanalgesic;
antineoplastic agent
nifedipine[no description available]medium10C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
nimodipine[no description available]medium102-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent
propanil[no description available]medium10anilide;
dichlorobenzene		herbicide
4-nitroquinoline-1-oxide[no description available]medium10C-nitro compound;
quinoline N-oxide		carcinogenic agent
chloramphenicol[no description available]medium10C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
kanamycin a[no description available]medium10kanamycinsbacterial metabolite
colchicine[no description available]medium10alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen
yohimbine hydrochloride[no description available]medium10
cycloheximide[no description available]medium10antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
acetopyrrothine[no description available]medium10acetamides;
dithiolopyrrolone antibiotic		angiogenesis inhibitor;
antibacterial agent;
antifungal agent;
antineoplastic agent;
bacterial metabolite;
chelator;
EC 2.7.7.6 (RNA polymerase) inhibitor;
marine metabolite;
protein synthesis inhibitor;
toxin
linuron[no description available]medium10dichlorobenzene;
phenylureas		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
Berberine chloride (TN)[no description available]medium10organic molecular entity
vinblastine[no description available]medium10
chlorbromuron[no description available]medium10ureas
benomyl[no description available]medium10aromatic amide;
benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		acaricide;
anthelminthic drug;
antifungal agrochemical;
microtubule-destabilising agent;
tubulin modulator
daunorubicin[no description available]medium20aminoglycoside antibiotic;
anthracycline;
p-quinones;
tetracenequinones		antineoplastic agent;
bacterial metabolite
paclitaxel[no description available]medium10taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
etoposide[no description available]medium10beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
niguldipine[no description available]medium10diarylmethane
topotecan[no description available]medium10pyranoindolizinoquinolineantineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor
benzylaminopurine[no description available]medium106-aminopurinescytokinin;
plant metabolite
voriconazole[no description available]medium10conazole antifungal drug;
difluorobenzene;
pyrimidines;
tertiary alcohol;
triazole antifungal drug		P450 inhibitor
gefitinib[no description available]medium10aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist
methotrexate[no description available]medium10dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
anisomycin[no description available]medium10monohydroxypyrrolidine;
organonitrogen heterocyclic antibiotic		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
antiparasitic agent;
bacterial metabolite;
DNA synthesis inhibitor;
protein synthesis inhibitor
tryptoquivaline[no description available]medium10aromatic ether;
indole alkaloid;
organic heteropentacyclic compound		breast cancer resistance protein inhibitor;
mycotoxin
ouabain[no description available]medium1011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
quinidine[no description available]medium10cinchona alkaloidalpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker
mycophenolic acid[no description available]medium102-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols		anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic
dactinomycin[no description available]medium20actinomycinmutagen
terbinafine[no description available]medium10acetylenic compound;
allylamine antifungal drug;
enyne;
naphthalenes;
tertiary amine		EC 1.14.13.132 (squalene monooxygenase) inhibitor;
P450 inhibitor;
sterol biosynthesis inhibitor
tamoxifen[no description available]medium10stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
lincomycin[no description available]medium10carbohydrate-containing antibiotic;
L-proline derivative;
monocarboxylic acid amide;
pyrrolidinecarboxamide;
S-glycosyl compound		antimicrobial agent;
bacterial metabolite
estrone sulfate[no description available]medium1017-oxo steroid;
steroid sulfate		human metabolite;
mouse metabolite
quercetin[no description available]medium107-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger
rhodamine 123[no description available]medium10organic chloride salt;
xanthene dye		fluorochrome
novobiocin[no description available]medium10carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent
rifampin[no description available]medium10cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
chitosan[no description available]medium10
vancomycin[no description available]medium10glycopeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite
tobramycin[no description available]medium10amino cyclitol glycosideantibacterial agent;
antimicrobial agent;
toxin
carbodiimides[no description available]medium10carbodiimide
lentinan[no description available]medium10
zwittergent 3-14[no description available]medium20organosulfonic acid
iodine[no description available]medium10diatomic iodinenutrient
sodium dodecyl sulfate[no description available]medium140organic sodium saltdetergent;
protein denaturant
cadmium[no description available]medium10cadmium molecular entity;
zinc group element atom
cetyltrimethylammonium ion[no description available]medium30quaternary ammonium ion
dizocilpine maleate[no description available]medium10maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
digitonin[no description available]medium20
3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate[no description available]medium701,1-diunsubstituted alkanesulfonate
deoxycholic acid[no description available]medium30bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human blood serum metabolite
singlet oxygen[no description available]medium10chalcogen;
monoatomic oxygen;
nonmetal atom		macronutrient
betaine[no description available]medium40amino-acid betaine;
glycine derivative		fundamental metabolite
zn(ii)-phthalocyanine[no description available]medium10metallophthalocyanine;
zinc tetrapyrrole		fluorochrome
empigen bb[no description available]medium20
ethanolamine[no description available]medium10ethanolamines;
primary alcohol;
primary amine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
atrial natriuretic factor[no description available]medium20polypeptide
dodecyltrimethylammonium[no description available]medium20quaternary ammonium ion
1-palmitoyl-2-oleoylphosphatidylcholine[no description available]medium10
phosphatidylcholines[no description available]medium201,2-diacyl-sn-glycero-3-phosphocholine
sodium hydroxide[no description available]medium10alkali metal hydroxide
triflusal[no description available]medium10benzoic acids;
carboxylic ester;
salicylates
salicylic acid[no description available]medium10monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
aspirin[no description available]medium10benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
salicylates[no description available]medium10monohydroxybenzoateplant metabolite
4-trifluoromethylsalicylic acid[no description available]medium10hydroxybenzoic acid
nonoxynol[no description available]medium10
cholic acid[no description available]medium2012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
bile acid;
C24-steroid;
trihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
glucose, (beta-d)-isomer[no description available]medium30D-glucopyranoseepitope;
mouse metabolite
methionine[no description available]medium20aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
leucine[no description available]medium10amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
phenylalanine[no description available]medium10amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid		algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
glutamic acid[no description available]medium10glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
nitrous acid[no description available]medium10nitrogen oxoacid
heparitin sulfate[no description available]medium10
polidocanol[no description available]medium10hydroxypolyetherhepatotoxic agent;
nonionic surfactant;
sclerotherapy agent
bilirubin diglucuronide[no description available]medium10
bilirubin[no description available]medium10biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
dithiothreitol[no description available]medium101,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol		chelator;
human metabolite;
reducing agent
mercaptoethanol[no description available]medium10alkanethiol;
primary alcohol		geroprotector
urea[no description available]medium10isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
guanidine[no description available]medium10carboxamidine;
guanidines;
one-carbon compound
serine[no description available]medium10L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
lysine[no description available]medium30aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
hyaluronoglucosaminidase[no description available]medium10
rhodamine 6g[no description available]medium10
dodecyldimethylamine oxide[no description available]medium10tertiary amine oxidedetergent;
plant metabolite
muramidase[no description available]medium20
1,2-heptanoylphosphatidylcholine[no description available]medium10
1-naphthylphenylamine[no description available]medium10naphthalenes
1-naphthylamine[no description available]medium10naphthylaminehuman xenobiotic metabolite
ethylene glycol[no description available]medium10ethanediol;
glycol		metabolite;
mouse metabolite;
solvent;
toxin
dodecyloctaethyleneglycol monoether[no description available]medium10hydroxypolyether
dodecyl-beta-d-maltoside[no description available]medium10disaccharide derivative;
glycoside		detergent
octyl glucoside[no description available]medium20beta-D-glucosideplant metabolite
chapso[no description available]medium10
inositol 1,4,5-trisphosphate[no description available]medium10myo-inositol trisphosphatemouse metabolite
3,3'-dithiobis(sulfosuccinimidyl propionate)[no description available]medium10
isoleucine[no description available]medium10aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
echinenone[no description available]medium10carotenoneanimal metabolite;
bacterial metabolite;
cofactor;
marine metabolite
tryptophan[no description available]medium10erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
chlorophyll a[no description available]medium10chlorophyll;
methyl ester		cofactor
arginine[no description available]medium10arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
bacteriochlorophylls[no description available]medium10bacteriochlorophyll;
methyl ester
amphotericin b[no description available]medium10antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
cellulase[no description available]medium10cellotriose
chloroform[no description available]medium10chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
4-chloromercuribenzenesulfonate[no description available]medium10arenesulfonic acid;
arylmercury compound
sarcosine[no description available]medium10N-alkylglycine zwitterion;
N-alkylglycine;
N-methyl-amino acid;
N-methylglycines		Escherichia coli metabolite;
glycine receptor agonist;
glycine transporter 1 inhibitor;
human metabolite;
mouse metabolite
sarkosyl[no description available]medium10
rubidium[no description available]medium10alkali metal atom
lysophosphatidylcholines[no description available]medium101-O-acyl-sn-glycero-3-phosphocholine
tromethamine[no description available]medium10primary amino compound;
triol		buffer
nitrophenols[no description available]medium10
cytochrome c-t[no description available]medium10
glycerol[no description available]low00alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
cetrimonium bromide[no description available]low00organic bromide salt;
quaternary ammonium salt		detergent;
surfactant
cholesteryl succinate[no description available]low00cholestane ester;
dicarboxylic acid monoester;
hemisuccinate		detergent
dodecylphosphocholine[no description available]low00phosphocholinesdetergent
thiamine triphosphate[no description available]low00ammonium betaine;
thiamine phosphate;
vitamin B1
cocamidopropyl betaine[no description available]low00ammonium betainesurfactant
3-(2,2,2-trimethylhydrazine)propionate[no description available]low00ammonium betainecardioprotective agent;
EC 1.14.11.1 (gamma-butyrobetaine dioxygenase) inhibitor;
neuroprotective agent
perifosine[no description available]low00ammonium betaine;
phospholipid		EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
nicotinate ribonucleoside[no description available]low00ammonium betainehuman metabolite
calcium crimson[no description available]low00ammonium betaine;
sulfonamide		fluorochrome
ConditionIndicatedRelationship StrengthStudiesTrials
Abscess0low10
Acute Confusional Senile Dementia0low10
Alloxan Diabetes0low10
Alzheimer Dementia0low10
Alzheimer Disease0low10
Alzheimer Disease, Early Onset0low10
Alzheimer Disease, Late Onset0low10
Alzheimer Sclerosis0low10
Alzheimer Syndrome0low10
Alzheimer Type Senile Dementia0low10
Alzheimer-Type Dementia (ATD)0low10
Alzheimer's Disease0low10
Alzheimer's Disease, Focal Onset0low10
Alzheimer's Diseases0low10
Amyloid Deposits0low10
Amyloid Plaques0low10
Cancer of Larynx0low10
Cancer of the Larynx0low10
Cardiac Hypertrophy0low10
Cardiomegaly0low10
Chondrosarcoma0low10
Dementia, Alzheimer Type0low10
Dementia, Presenile0low10
Dementia, Primary Senile Degenerative0low10
Dementia, Senile0low10
Diabetes Mellitus, Experimental0low10
Early Onset Alzheimer Disease0low10
Enlarged Heart0low10
Experimental Diabetes Mellitus0low10
Extravascular Hemolysis0low10
Familial Alzheimer Disease (FAD)0low10
Focal Onset Alzheimer's Disease0low10
Granuloma0low10
Granulomas0low10
Haemolysis0low10
Heart Enlargement0low10
Heart Hypertrophy0low10
Hemolysis0low10
Infections, Orthomyxoviridae0low10
Infections, Orthomyxovirus0low10
Infertility, Male0low10
Intravascular Hemolysis0low10
Laryngeal Cancer0low10
Laryngeal Neoplasms0low10
Larynx Cancer0low10
Larynx Neoplasms0low10
Late Onset Alzheimer Disease0low10
Meningitis0low10
Neoplasms, Laryngeal0low10
Neuritic Plaques0low10
Orthomyxoviridae Infections0low10
Orthomyxovirus Infections0low10
Pachymeningitis0low10
Plaque, Amyloid0low10
Plaques, Amyloid0low10
Pregnancy0low20
Presenile Alzheimer Dementia0low10
Primary Senile Degenerative Dementia0low10
Senile Dementia, Acute Confusional0low10
Senile Dementia, Alzheimer Type0low10
Senile Plaques0low10
Sensitivity and Specificity0low10
Sterility, Male0low10
Streptozocin Diabetes0low10
Streptozotocin Diabetes0low10
Sub-Fertility, Male0low10
Subfertility, Male0low10
Swine Influenza0low10

Research Highlights

Pharmacokinetics (1)

ArticleYear
A randomized, double-blind, three-arm, parallel group, single-dose phase I study to evaluate the pharmacokinetic similarity between SB12 (a proposed eculizumab biosimilar) and eculizumab (Soliris) in healthy subjects.
International journal of clinical pharmacology and therapeutics, Volume: 60, Issue: 6		2022
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (1)

ArticleYear
In situ rearranged multifunctional lipid nanoparticles via synergistic potentiation for oral insulin delivery.
International journal of pharmaceutics, Apr-05, Volume: 636		2023
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (3)

ArticleYear
Fluorophotometric determination of critical micelle concentration (CMC) of ionic and non-ionic surfactants with carbon dots via Stokes shift.
Talanta, Volume: 132		2015
Effects of membrane partitioning and other physical chemical properties on the apparent potency of "membrane active" compounds evaluated using red blood cell lysis assays.
Analytical biochemistry, Apr-15, Volume: 303, Issue: 2		2002
ANF stimulation of detergent-dispersed particulate guanylate cyclase from bovine adrenal cortex.
FEBS letters, Jan-06, Volume: 194, Issue: 2		1986
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]