Page last updated: 2024-08-07 23:28:59
Carbonic anhydrase
[no definition available]
Synonyms
EC 4.2.1.1
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (75)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| bromide | Methanosarcina thermophila | Ki | 8,700.0000 | 1 | 1 |
| hydrobromic acid | Methanosarcina thermophila | Ki | 160,000.0000 | 1 | 1 |
| chlorine | Methanosarcina thermophila | Ki | 8,800.0000 | 1 | 1 |
| hydrochloric acid | Methanosarcina thermophila | Ki | 200,000.0000 | 1 | 1 |
| hydrogen sulfide | Methanosarcina thermophila | Ki | 50.0000 | 1 | 1 |
| carbonic acid | Methanosarcina thermophila | Ki | 24,350.0000 | 1 | 2 |
| hydrogen cyanide | Methanosarcina thermophila | Ki | 680.0000 | 1 | 1 |
| hydrogen carbonate | Methanosarcina thermophila | Ki | 3,000.0000 | 1 | 1 |
| thiocyanic acid | Methanosarcina thermophila | Ki | 7,000.0000 | 1 | 1 |
| nitrates | Methanosarcina thermophila | Ki | 7,800.0000 | 1 | 1 |
| nitric acid | Methanosarcina thermophila | Ki | 36,500.0000 | 1 | 1 |
| nitrites | Methanosarcina thermophila | Ki | 8,700.0000 | 1 | 1 |
| sulfuric acid | Methanosarcina thermophila | Ki | 105,850.0000 | 1 | 2 |
| acetazolamide | Methanosarcina thermophila | Ki | 0.2848 | 8 | 8 |
| celecoxib | Methanosarcina thermophila | Ki | 0.5750 | 2 | 2 |
| dichlorphenamide | Methanosarcina thermophila | Ki | 0.1700 | 2 | 2 |
| ethoxzolamide | Methanosarcina thermophila | Ki | 0.4700 | 2 | 2 |
| mafenide | Methanosarcina thermophila | Ki | 4.4250 | 2 | 2 |
| methazolamide | Methanosarcina thermophila | Ki | 0.1550 | 2 | 2 |
| sodium fluoride | Methanosarcina thermophila | Ki | 200,000.0000 | 3 | 3 |
| sodium iodide | Methanosarcina thermophila | Ki | 160,000.0000 | 3 | 3 |
| sulfanilamide | Methanosarcina thermophila | Ki | 2.0900 | 2 | 2 |
| cyanides | Methanosarcina thermophila | Ki | 8,400.0000 | 1 | 1 |
| sulfamic acid | Methanosarcina thermophila | Ki | 2,422.6125 | 4 | 4 |
| benzenearsonic acid | Methanosarcina thermophila | Ki | 91.0000 | 1 | 1 |
| sodium cyanide | Methanosarcina thermophila | Ki | 680.0000 | 3 | 3 |
| thiocyanate | Methanosarcina thermophila | Ki | 13,100.0000 | 1 | 1 |
| sodium carbonate | Methanosarcina thermophila | Ki | 6,700.0000 | 3 | 3 |
| hydrofluoric acid | Methanosarcina thermophila | Ki | 200,000.0000 | 1 | 1 |
| carbonates | Methanosarcina thermophila | Ki | 8,200.0000 | 1 | 1 |
| sodium nitrate | Methanosarcina thermophila | Ki | 36,500.0000 | 3 | 3 |
| sodium sulfate | Methanosarcina thermophila | Ki | 200,000.0000 | 3 | 3 |
| nitrous acid | Methanosarcina thermophila | Ki | 6,800.0000 | 1 | 1 |
| hydrazoic acid | Methanosarcina thermophila | Ki | 5,800.0000 | 1 | 1 |
| hydroiodic acid | Methanosarcina thermophila | Ki | 160,000.0000 | 1 | 1 |
| sodium bisulfide | Methanosarcina thermophila | Ki | 50.0000 | 3 | 3 |
| fluorides | Methanosarcina thermophila | Ki | 21,300.0000 | 1 | 1 |
| iodine | Methanosarcina thermophila | Ki | 6,300.0000 | 1 | 1 |
| sodium azide | Methanosarcina thermophila | Ki | 5,800.0000 | 3 | 3 |
| azides | Methanosarcina thermophila | Ki | 8,700.0000 | 1 | 1 |
| benzeneboronic acid | Methanosarcina thermophila | Ki | 155.5000 | 2 | 2 |
| 4-amino-6-chloro-1,3-benzenedisulfonamide | Methanosarcina thermophila | Ki | 0.3650 | 2 | 2 |
| 2,4-disulfamyl-5-trifluoromethylaniline | Methanosarcina thermophila | Ki | 0.8900 | 2 | 2 |
| sulfamide | Methanosarcina thermophila | Ki | 57.4550 | 4 | 4 |
| hydrogen sulfite | Methanosarcina thermophila | Ki | 200,000.0000 | 1 | 2 |
| valdecoxib | Methanosarcina thermophila | Ki | 0.1850 | 2 | 2 |
| perchlorate | Methanosarcina thermophila | Ki | 200,000.0000 | 1 | 1 |
| perrhenate | Methanosarcina thermophila | Ki | 200,000.0000 | 1 | 1 |
| 4-(2-aminoethyl)benzenesulfonamide | Methanosarcina thermophila | Ki | 0.2000 | 2 | 2 |
| sodium bromide | Methanosarcina thermophila | Ki | 126,666.6667 | 3 | 3 |
| sodium thiocyanate | Methanosarcina thermophila | Ki | 7,000.0000 | 2 | 2 |
| sodium bicarbonate | Methanosarcina thermophila | Ki | 42,000.0000 | 3 | 3 |
| sodium cyanate | Methanosarcina thermophila | Ki | 90.0000 | 2 | 2 |
| pyrophosphate | Methanosarcina thermophila | Ki | 7,300.0000 | 1 | 1 |
| dorzolamide | Methanosarcina thermophila | Ki | 1.0600 | 2 | 2 |
| topiramate | Methanosarcina thermophila | Ki | 0.5700 | 2 | 2 |
| tetraborate | Methanosarcina thermophila | Ki | 7,200.0000 | 1 | 1 |
| sodium | Methanosarcina thermophila | Ki | 7,000.0000 | 1 | 1 |
| sodium bisulfite | Methanosarcina thermophila | Ki | 11,700.0000 | 2 | 2 |
| sodium nitrite | Methanosarcina thermophila | Ki | 6,800.0000 | 3 | 3 |
Drugs with Other Measurements
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Anion inhibition profiles of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.Bioorganic & medicinal chemistry, , 08-15, Volume: 24, Issue:16, 2016
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.Bioorganic & medicinal chemistry letters, , Dec-20, Volume: 14, Issue:24, 2004
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
Anion inhibition profiles of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.Bioorganic & medicinal chemistry, , 08-15, Volume: 24, Issue:16, 2016
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions.Bioorganic & medicinal chemistry letters, , Sep-06, Volume: 14, Issue:17, 2004
Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.Bioorganic & medicinal chemistry letters, , Dec-20, Volume: 14, Issue:24, 2004
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
Anion inhibition profiles of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.Bioorganic & medicinal chemistry, , 08-15, Volume: 24, Issue:16, 2016
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions.Bioorganic & medicinal chemistry letters, , Sep-06, Volume: 14, Issue:17, 2004
Anion inhibition profiles of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.Bioorganic & medicinal chemistry, , 08-15, Volume: 24, Issue:16, 2016
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions.Bioorganic & medicinal chemistry letters, , Sep-06, Volume: 14, Issue:17, 2004
Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides.Bioorganic & medicinal chemistry letters, , Dec-20, Volume: 14, Issue:24, 2004
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013
[no title available]Bioorganic & medicinal chemistry, , 01-15, Volume: 25, Issue:2, 2017
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.Bioorganic & medicinal chemistry, , Aug-01, Volume: 23, Issue:15, 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.Bioorganic & medicinal chemistry letters, , Jul-15, Volume: 23, Issue:14, 2013