Page last updated: 2024-10-27

vanoxerine and Sensitivity and Specificity

vanoxerine has been researched along with Sensitivity and Specificity in 3 studies

vanoxerine: structure given in first source
vanoxerine : An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Williams, JM1
Steketee, JD1
Harada, N1
Ohba, H1
Fukumoto, D1
Kakiuchi, T1
Tsukada, H1
Davidson, C1
Ellinwood, EH1
Douglas, SB1
Lee, TH1

Other Studies

3 other studies available for vanoxerine and Sensitivity and Specificity

ArticleYear
Characterization of dopamine transport in crude synaptosomes prepared from rat medial prefrontal cortex.
    Journal of neuroscience methods, 2004, Aug-30, Volume: 137, Issue:2

    Topics: Animals; Biological Transport; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopam

2004
Potential of [(18)F]beta-CFT-FE (2beta-carbomethoxy-3beta-(4-fluorophenyl)-8-(2-[(18)F]fluoroethyl)nortropane) as a dopamine transporter ligand: A PET study in the conscious monkey brain.
    Synapse (New York, N.Y.), 2004, Volume: 54, Issue:1

    Topics: Anesthetics; Animals; Brain; Carbon Radioisotopes; Consciousness; Dopamine Plasma Membrane Transport

2004
Effect of cocaine, nomifensine, GBR 12909 and WIN 35428 on carbon fiber microelectrode sensitivity for voltammetric recording of dopamine.
    Journal of neuroscience methods, 2000, Aug-15, Volume: 101, Issue:1

    Topics: Animals; Artifacts; Calibration; Carbon; Coated Materials, Biocompatible; Cocaine; Dopamine; Dopamin

2000