pyridoxal phosphate has been researched along with Sensitivity and Specificity in 62 studies
Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study testifies an assumption on epilepsy as an inborn error of pyridoxine metabolism and suggests non-invasive quantitative biomarkers for clarified evaluation of clinical status and monitoring an individual treatment by antiepileptic drugs." | 9.16 | Epilepsy as a pyridoxine-dependent condition: quantified urinary biomarkers for status evaluation and monitoring antiepileptic treatment. ( Dolina, S; Malitsky, S; Margalit, D; Pressman, E; Rabinkov, A, 2012) |
| "The study testifies an assumption on epilepsy as an inborn error of pyridoxine metabolism and suggests non-invasive quantitative biomarkers for clarified evaluation of clinical status and monitoring an individual treatment by antiepileptic drugs." | 5.16 | Epilepsy as a pyridoxine-dependent condition: quantified urinary biomarkers for status evaluation and monitoring antiepileptic treatment. ( Dolina, S; Malitsky, S; Margalit, D; Pressman, E; Rabinkov, A, 2012) |
| "We investigated the relation between the ratio plasma 4-pyridoxic acid: (pyridoxal + pyridoxal-5'-phosphate) (PAr) as an indicator of altered vitamin B-6 homeostasis and the risk of stroke in the general population." | 3.88 | The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK). ( Meyer, K; Midttun, Ø; Nygård, O; Tell, GS; Ueland, PM; Ulvik, A; Vollset, SE; Zuo, H, 2018) |
| "Twenty-one patients with 39 hepatocellular carcinomas underwent ferumoxides-enhanced and mangafodipir trisodium-enhanced MR imaging." | 2.70 | Preoperative detection of hepatocellular carcinoma: ferumoxides-enhanced versus mangafodipir trisodium-enhanced MR imaging. ( Choi, D; Kim, H; Kim, SH; Kim, SK; Lee, SJ; Lee, WJ; Lim, HK; Lim, JH; Seo, JW, 2002) |
| " Adverse events were reported for 23% of the patients; most were mild to moderate in intensity, did not require treatment, and were not drug related." | 2.69 | Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety). ( Anderson, MW; Borello, JA; Bova, JG; Brown, JJ; Chezmar, JL; Dachman, AH; Federle, MP; Fenstermacher, M; Foster, GS; Francis, IR; Freeny, PC; Halford, HH; Harmon, B; Harms, SE; Johnson, CD; Kenney, PJ; Klippenstein, DL; Lee, JK; Mattrey, R; Mitchell, DG; Pelsang, RE; Rubin, DL; Saini, S; Semelka, RC; Turner, DA; Weinreb, JC, 2000) |
| "Fifty patients with liver cirrhosis and histologically proven HCC were enrolled in a prospective phase-IIIB clinical trial." | 2.69 | MnDPDP-enhanced MRI vs dual-phase spiral CT in the detection of hepatocellular carcinoma in cirrhosis. ( Bartolozzi, C; Cioni, D; Crocetti, L; Donati, F; Lencioni, R, 2000) |
| "Forty-six patients with 96 hepatocellular carcinomas underwent Mn-DPDP- and gadopentetate dimeglumine-enhanced MRI." | 1.32 | MRI for detection of hepatocellular carcinoma: comparison of mangafodipir trisodium and gadopentetate dimeglumine contrast agents. ( Kim, CS; Lee, JM; Youk, JH, 2004) |
| "Histidine 143 has been replaced by either alanine or asparagine." | 1.29 | NMR studies of 1H resonances in the 10-18-ppm range for aspartate aminotransferase from Escherichia coli. ( Hayashi, H; Hirotsu, K; Kagamiyama, H; Kuramitsu, S; Metzler, CM; Metzler, DE; Miyahara, I; Mollova, ET; Scott, RD; Yano, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (20.97) | 18.2507 |
| 2000's | 39 (62.90) | 29.6817 |
| 2010's | 8 (12.90) | 24.3611 |
| 2020's | 2 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, DE | 1 |
| You, S | 1 |
| Huo, W | 1 |
| Han, X | 1 |
| Xu, H | 1 |
| Jenčo, J | 1 |
| Krčmová, LK | 1 |
| Sobotka, L | 1 |
| Bláha, V | 1 |
| Solich, P | 1 |
| Švec, F | 1 |
| Zuo, H | 1 |
| Tell, GS | 1 |
| Ueland, PM | 1 |
| Nygård, O | 1 |
| Vollset, SE | 1 |
| Midttun, Ø | 1 |
| Meyer, K | 1 |
| Ulvik, A | 1 |
| Gennero, I | 1 |
| Conte-Auriol, F | 1 |
| Salles, JP | 1 |
| Fouad Mansour, M | 1 |
| Assefa, M | 1 |
| El-Khouly, A | 1 |
| Zhu, P | 1 |
| Van Schepdael, A | 1 |
| Adams, E | 1 |
| Ghassabian, S | 1 |
| Griffiths, L | 1 |
| Smith, MT | 1 |
| Harr, KE | 1 |
| Allison, K | 1 |
| Bonde, RK | 1 |
| Murphy, D | 1 |
| Harvey, JW | 1 |
| Bae, K | 1 |
| Na, JB | 1 |
| Choi, DS | 1 |
| Cho, JM | 1 |
| Choi, HC | 1 |
| Jeon, KN | 1 |
| Park, MJ | 1 |
| Choi, HY | 1 |
| Kim, JE | 1 |
| Chung, SH | 1 |
| Dolina, S | 1 |
| Margalit, D | 1 |
| Malitsky, S | 1 |
| Pressman, E | 1 |
| Rabinkov, A | 1 |
| van Zelst, BD | 1 |
| de Jonge, R | 1 |
| Norris, FC | 1 |
| Betts-Henderson, J | 1 |
| Wells, JA | 1 |
| Cleary, JO | 1 |
| Siow, BM | 1 |
| Walker-Samuel, S | 1 |
| McCue, K | 1 |
| Salomoni, P | 1 |
| Scambler, PJ | 1 |
| Lythgoe, MF | 1 |
| Schima, W | 2 |
| Függer, R | 1 |
| Schober, E | 1 |
| Oettl, C | 1 |
| Wamser, P | 1 |
| Grabenwöger, F | 1 |
| Ryan, JM | 1 |
| Novacek, G | 1 |
| Kim, SK | 1 |
| Kim, SH | 2 |
| Lee, WJ | 1 |
| Kim, H | 1 |
| Seo, JW | 1 |
| Choi, D | 1 |
| Lim, HK | 1 |
| Lee, SJ | 1 |
| Lim, JH | 1 |
| Han, Q | 1 |
| Xu, M | 1 |
| Tang, L | 1 |
| Tan, X | 2 |
| Tan, Y | 1 |
| Hoffman, RM | 1 |
| Rieger, J | 1 |
| Körner, M | 1 |
| Linsenmaier, U | 1 |
| Rock, C | 1 |
| Wirth, S | 1 |
| Pfeifer, KJ | 1 |
| Talwar, D | 1 |
| Quasim, T | 1 |
| McMillan, DC | 1 |
| Kinsella, J | 1 |
| Williamson, C | 1 |
| O'Reilly, DS | 1 |
| Fayad, LM | 1 |
| Holland, GA | 1 |
| Bergin, D | 1 |
| Iqbal, N | 1 |
| Parker, L | 1 |
| Curcillo, PG | 1 |
| Kowalski, TE | 1 |
| Park, P | 1 |
| Intenzo, C | 1 |
| Mitchell, DG | 4 |
| Mizushina, Y | 1 |
| Xu, X | 1 |
| Matsubara, K | 1 |
| Murakami, C | 1 |
| Kuriyama, I | 1 |
| Oshige, M | 1 |
| Takemura, M | 1 |
| Kato, N | 1 |
| Yoshida, H | 1 |
| Sakaguchi, K | 1 |
| Bartolozzi, C | 3 |
| Donati, F | 3 |
| Cioni, D | 2 |
| Procacci, C | 1 |
| Morana, G | 1 |
| Chiesa, A | 1 |
| Grazioli, L | 1 |
| Cittadini, G | 2 |
| Giovagnoni, A | 1 |
| Gandini, G | 1 |
| Maass, J | 1 |
| Lencioni, R | 2 |
| Yeh, BM | 1 |
| Breiman, RS | 1 |
| Taouli, B | 1 |
| Qayyum, A | 1 |
| Roberts, JP | 1 |
| Coakley, FV | 1 |
| Ramsay, D | 1 |
| Marshall, M | 1 |
| Song, S | 1 |
| Zimmerman, M | 1 |
| Edmunds, S | 1 |
| Yusoff, I | 1 |
| Cullingford, G | 1 |
| Fletcher, D | 1 |
| Mendelson, R | 1 |
| Dolzan, M | 1 |
| Johansson, K | 1 |
| Roig-Zamboni, V | 1 |
| Campanacci, V | 1 |
| Tegoni, M | 1 |
| Schneider, G | 1 |
| Cambillau, C | 1 |
| Tutor-Crespo, MJ | 1 |
| Hermida, J | 1 |
| Tutor, JC | 1 |
| Zanello, A | 1 |
| Nicoletti, R | 1 |
| Brambilla, P | 1 |
| Boccuni, R | 1 |
| Di Carlo, V | 1 |
| Staudacher, C | 1 |
| Del Maschio, A | 1 |
| Youk, JH | 1 |
| Lee, JM | 1 |
| Kim, CS | 1 |
| Ryeom, HK | 1 |
| Choe, BH | 1 |
| Kim, JY | 1 |
| Kwon, S | 1 |
| Ko, CW | 1 |
| Kim, HM | 1 |
| Lee, SB | 1 |
| Kang, DS | 1 |
| Sahani, DV | 2 |
| Kalva, SP | 2 |
| Fischman, AJ | 2 |
| Kadavigere, R | 1 |
| Blake, M | 1 |
| Hahn, PF | 3 |
| Saini, S | 5 |
| Ryan, D | 1 |
| Mueller, P | 1 |
| Assaban, M | 1 |
| Aubé, C | 1 |
| Lebigot, J | 1 |
| Ridereau-Zins, C | 1 |
| Hamy, A | 1 |
| Caron, C | 1 |
| Boraschi, P | 1 |
| Gigoni, R | 1 |
| Caramella, D | 1 |
| Boggi, U | 1 |
| Falaschi, F | 1 |
| Regge, D | 1 |
| Campanella, D | 1 |
| Anselmetti, GC | 1 |
| Cirillo, S | 1 |
| Gallo, TM | 1 |
| Muratore, A | 1 |
| Capussotti, L | 1 |
| Galatola, G | 1 |
| Floriani, I | 1 |
| Aglietta, M | 1 |
| Choi, JY | 1 |
| Kim, MJ | 1 |
| Kim, JH | 1 |
| Ko, HK | 1 |
| Lim, JS | 1 |
| Oh, YT | 1 |
| Chung, JJ | 2 |
| Yoo, HS | 1 |
| Lee, JT | 1 |
| Kim, KW | 1 |
| Koh, DM | 2 |
| Brown, G | 2 |
| Meer, Z | 1 |
| Norman, AR | 1 |
| Husband, JE | 2 |
| Sharif, S | 1 |
| Huot, MC | 1 |
| Tolstoy, PM | 1 |
| Toney, MD | 1 |
| Jonsson, KH | 1 |
| Limbach, HH | 1 |
| Gates, AT | 1 |
| Lowry, M | 1 |
| Fletcher, KA | 1 |
| Murugeshu, A | 1 |
| Rusin, O | 1 |
| Robinson, JW | 1 |
| Strongin, RM | 1 |
| Warner, IM | 1 |
| Riddell, AM | 1 |
| Scurr, E | 1 |
| Collins, DJ | 1 |
| Allen, SD | 1 |
| Chau, I | 1 |
| Cunningham, D | 1 |
| deSouza, NM | 1 |
| Leach, MO | 1 |
| Metzler, DE | 2 |
| Metzler, CM | 2 |
| Mollova, ET | 2 |
| Scott, RD | 2 |
| Tanase, S | 1 |
| Kogo, K | 1 |
| Higaki, T | 1 |
| Morino, Y | 1 |
| Kagamiyama, H | 1 |
| Yano, T | 1 |
| Kuramitsu, S | 1 |
| Hayashi, H | 1 |
| Hirotsu, K | 1 |
| Miyahara, I | 1 |
| Rofsky, NM | 1 |
| Weinreb, JC | 3 |
| Bernardino, ME | 2 |
| Young, SW | 3 |
| Lee, JK | 4 |
| Noz, ME | 1 |
| Slater, GJ | 1 |
| Mayo-smith, WW | 1 |
| Sharma, P | 1 |
| Eisenberg, PJ | 1 |
| Toft, KG | 1 |
| Friisk, GA | 1 |
| Skotland, T | 1 |
| Mascher, HJ | 1 |
| Wang, C | 1 |
| Bates, CJ | 1 |
| Pentieva, KD | 1 |
| Matthews, N | 1 |
| Macdonald, A | 1 |
| Bültmann, R | 1 |
| Trendelenburg, M | 1 |
| Tuluc, F | 1 |
| Wittenburg, H | 1 |
| Starke, K | 1 |
| Melnyk, S | 1 |
| Pogribna, M | 1 |
| Pogribny, IP | 1 |
| Yi, P | 1 |
| James, SJ | 1 |
| Federle, MP | 1 |
| Chezmar, JL | 1 |
| Rubin, DL | 2 |
| Freeny, PC | 1 |
| Semelka, RC | 3 |
| Brown, JJ | 2 |
| Borello, JA | 1 |
| Mattrey, R | 2 |
| Dachman, AH | 2 |
| Harmon, B | 1 |
| Fenstermacher, M | 1 |
| Pelsang, RE | 1 |
| Harms, SE | 2 |
| Halford, HH | 2 |
| Anderson, MW | 2 |
| Johnson, CD | 1 |
| Francis, IR | 1 |
| Bova, JG | 1 |
| Kenney, PJ | 1 |
| Klippenstein, DL | 1 |
| Foster, GS | 1 |
| Turner, DA | 1 |
| Federle, M | 1 |
| Chezmar, J | 1 |
| Weinreb, J | 1 |
| Freeny, P | 1 |
| Schmiedl, UP | 1 |
| Borrello, JA | 1 |
| Bennett, WF | 1 |
| Rifkin, M | 1 |
| Gay, SB | 1 |
| Ballerini, R | 1 |
| Sherwin, PF | 1 |
| Robison, RO | 1 |
| Crocetti, L | 1 |
| Martin, DR | 1 |
| Balci, NC | 1 |
| Wilber, K | 1 |
| Valls, F | 1 |
| Sancho, MT | 1 |
| Fernández-Muiño, MA | 1 |
| Checa, MA | 1 |
| Mann, GN | 1 |
| Marx, HF | 1 |
| Lai, LL | 1 |
| Wagman, LD | 1 |
| Helmberger, TK | 1 |
| Laubenberger, J | 1 |
| Rummeny, E | 1 |
| Jung, G | 1 |
| Sievers, K | 1 |
| Döhring, W | 1 |
| Meurer, K | 1 |
| Reiser, MF | 1 |
| Oudkerk, M | 1 |
| Torres, CG | 1 |
| Song, B | 1 |
| König, M | 1 |
| Grimm, J | 1 |
| Fernandez-Cuadrado, J | 1 |
| Op de Beeck, B | 1 |
| Marquardt, M | 1 |
| van Dijk, P | 1 |
| de Groot, JC | 1 |
| Braga, HJ | 1 |
| Choti, MA | 1 |
| Lee, VS | 1 |
| Paulson, EK | 1 |
| Siegelman, ES | 1 |
| Bluemke, DA | 1 |
| Tong, JC | 1 |
| Mackay, IR | 1 |
| Chin, J | 1 |
| Law, RH | 1 |
| Fayad, K | 1 |
| Rowley, MJ | 1 |
| Dobritz, M | 1 |
| Fellner, FA | 1 |
| Baum, U | 1 |
| Nömayr, A | 1 |
| Lell, M | 1 |
| Klein, P | 1 |
| Papadopoulos, T | 1 |
| Bautz, W | 1 |
| Steudel, A | 1 |
| Layer, G | 1 |
| Kraheck, H | 1 |
| Hartlapp, J | 1 |
| Reiser, M | 1 |
| Hirose, N | 1 |
| Kubo, N | 1 |
| Tsuge, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Hordaland Health Studies (HHS)[NCT03013725] | 36,000 participants (Actual) | Observational | 1992-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 trials available for pyridoxal phosphate and Sensitivity and Specificity
| Article | Year |
|---|---|
Contrast-enhanced MR cholangiography: comparison of Gd-EOB-DTPA and Mn-DPDP in healthy volunteers.
Topics: Adult; Bile Ducts; Cholangiography; Cholangiopancreatography, Magnetic Resonance; Contrast Media; Ed | 2012 |
Epilepsy as a pyridoxine-dependent condition: quantified urinary biomarkers for status evaluation and monitoring antiepileptic treatment.
Topics: Adolescent; Anticonvulsants; Biomarkers; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Py | 2012 |
Preoperative detection of hepatocellular carcinoma: ferumoxides-enhanced versus mangafodipir trisodium-enhanced MR imaging.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Contrast Media; Dextrans; Edetic Acid; False Negative Reacti | 2002 |
[Focal secondary malignant liver lesions: MnDPDP-enhanced MRT at 0.2 tesla vs. helical CT-arterioportography].
Topics: Adult; Aged; Contrast Media; Edetic Acid; Female; Humans; Image Enhancement; Liver Neoplasms; Magnet | 2002 |
Detection of colorectal liver metastases: a prospective multicenter trial comparing unenhanced MRI, MnDPDP-enhanced MRI, and spiral CT.
Topics: Adult; Aged; Colorectal Neoplasms; Contrast Media; Edetic Acid; Female; Humans; Liver Neoplasms; Mag | 2004 |
Detection of hepatic metastasis: manganese- and ferucarbotran-enhanced MR imaging.
Topics: Adult; Aged; Contrast Media; Dextrans; Edetic Acid; Female; Ferrosoferric Oxide; Humans; Image Enhan | 2006 |
Diagnostic accuracy of rim and segmental MRI enhancement of colorectal hepatic metastasis after administration of mangafodipir trisodium.
Topics: Adult; Aged; Colorectal Neoplasms; Contrast Media; Edetic Acid; Female; Humans; Image Enhancement; L | 2007 |
Hepatocellular tumors: characterization with Mn-DPDP-enhanced MR imaging.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Contrast Media; Diagnosis, Differential; | 1993 |
Mn-DPDP enhanced MR imaging of the liver: analysis of pulse sequence performance.
Topics: Adult; Aged; Contrast Media; Edetic Acid; Female; Humans; Image Enhancement; Liver; Liver Diseases; | 1996 |
Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5'-phosphate concentrations.
Topics: Adult; Chromatography, High Pressure Liquid; Electrochemistry; Female; Homocysteine; Humans; Indicat | 2000 |
Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety).
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Contrast Media; Diagnosis, | 2000 |
Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging.
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Diagnosis, Differential; Edetic Acid; Female; Humans | 2000 |
MnDPDP-enhanced MRI vs dual-phase spiral CT in the detection of hepatocellular carcinoma in cirrhosis.
Topics: Carcinoma, Hepatocellular; Edetic Acid; Female; Follow-Up Studies; Humans; Iodized Oil; Liver Cirrho | 2000 |
MRI characteristics in focal hepatic disease before and after administration of MnDPDP: discriminant analysis as a diagnostic tool.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Carcinoma, Hepatocellular; Colorectal Neoplasms; Contrast | 2002 |
Characterization of liver lesions with mangafodipir trisodium-enhanced MR imaging: multicenter study comparing MR and dual-phase spiral CT.
Topics: Adult; Aged; Chi-Square Distribution; Contrast Media; Diagnosis, Differential; Edetic Acid; Female; | 2002 |
[Manganese-DPDP in the MR tomography of malignant liver tumors. The initial results with a new hepatobiliary contrast agent].
Topics: Adult; Aged; Contrast Media; Drug Evaluation; Edetic Acid; Humans; Infusions, Intravenous; Liver; Li | 1992 |
46 other studies available for pyridoxal phosphate and Sensitivity and Specificity
| Article | Year |
|---|---|
Colorimetric detection of alkaline phosphatase activity based on pyridoxal phosphate-induced chromatic switch of polydiacetylene nano-liposomes.
Topics: Alkaline Phosphatase; Colorimetry; Liposomes; Nanostructures; Polyacetylene Polymer; Pyridoxal Phosp | 2022 |
Development of novel liquid chromatography method for clinical monitoring of vitamin B
Topics: Administration, Oral; Adult; Blood Chemical Analysis; Calibration; Chromatography, High Pressure Liq | 2020 |
The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK).
Topics: Aged; Body Mass Index; C-Reactive Protein; Exercise; Female; Follow-Up Studies; Health Surveys; Home | 2018 |
Laboratory diagnosis of hypophosphatasia.
Topics: Alkaline Phosphatase; Biomarkers; Clinical Laboratory Techniques; Diagnosis, Differential; Humans; H | 2017 |
Development of a reversed phase liquid chromatographic method for analysis of pyridoxal-5'-phosphate and its impurities.
Topics: Chromatography, Reverse-Phase; Drug Contamination; Linear Models; Pyridoxal Phosphate; Reproducibili | 2018 |
A novel fully validated LC-MS/MS method for quantification of pyridoxal-5'-phosphate concentrations in samples of human whole blood.
Topics: Animals; Cattle; Chromatography, Liquid; Humans; Linear Models; Pyridoxal Phosphate; Reproducibility | 2015 |
Comparison of blood aminotransferase methods for assessment of myopathy and hepatopathy in Florida manatees (Trichechus manatus latirostris).
Topics: Alanine Transaminase; Animals; Animals, Wild; Aspartate Aminotransferases; Blood Specimen Collection | 2008 |
A stable isotope dilution LC-ESI-MS/MS method for the quantification of pyridoxal-5'-phosphate in whole blood.
Topics: Chromatography, Reverse-Phase; Humans; Pyridoxal Phosphate; Reproducibility of Results; Sensitivity | 2012 |
Enhanced tissue differentiation in the developing mouse brain using magnetic resonance micro-histology.
Topics: Animals; Brain; Contrast Media; Diagnosis, Differential; Edetic Acid; Female; Gadolinium DTPA; Image | 2013 |
Diagnosis and staging of pancreatic cancer: comparison of mangafodipir trisodium-enhanced MR imaging and contrast-enhanced helical hydro-CT.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Contrast Media; Diagnosis, Differential; Edetic Acid | 2002 |
Homogeneous, nonradioactive, enzymatic assay for plasma pyridoxal 5-phosphate.
Topics: Animals; Apoenzymes; Humans; Indicators and Reagents; Lyases; Pyridoxal Phosphate; Recombinant Prote | 2002 |
[Organ specific MRI contrast media in general practice].
Topics: Contrast Media; Dextrans; Edetic Acid; Ferrosoferric Oxide; Humans; Iron; Liver Neoplasms; Lung Neop | 2002 |
Optimisation and validation of a sensitive high-performance liquid chromatography assay for routine measurement of pyridoxal 5-phosphate in human plasma and red cells using pre-column semicarbazide derivatisation.
Topics: Calibration; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Pyridoxal Phosphate; Refere | 2003 |
Functional magnetic resonance cholangiography (fMRC) of the gallbladder and biliary tree with contrast-enhanced magnetic resonance cholangiography.
Topics: Biliary Tract; Biliary Tract Diseases; Cholecystitis; Contrast Media; Edetic Acid; Female; Gallbladd | 2003 |
Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase alpha and epsilon.
Topics: Cell Survival; DNA Polymerase I; DNA Polymerase II; Dose-Response Relationship, Drug; Enzyme Inhibit | 2003 |
Biliary tract depiction in living potential liver donors: comparison of conventional MR, mangafodipir trisodium-enhanced excretory MR, and multi-detector row CT cholangiography--initial experience.
Topics: Adolescent; Adult; Bile Ducts; Cholangiography; Contrast Media; Edetic Acid; Female; Humans; Image E | 2004 |
Identification and staging of pancreatic tumours using computed tomography, endoscopic ultrasound and mangafodipir trisodium-enhanced magnetic resonance imaging.
Topics: Contrast Media; Edetic Acid; Endosonography; Female; Humans; Lymphatic Metastasis; Magnetic Resonanc | 2004 |
Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Conserved Sequence; Crystallography, X-Ray; | 2004 |
Activation of serum aminotransferases by pyridoxal-5' -phosphate in epileptic patients treated with anticonvulsant drugs.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Carbamazepine; Drug Therapy, Combination; | 2004 |
Magnetic resonance with manganese-DPDP (mangafodipir) of focal solid pancreatic lesions.
Topics: Adult; Aged; Contrast Media; Edetic Acid; Female; Humans; Magnetic Resonance Imaging; Male; Middle A | 2004 |
MRI for detection of hepatocellular carcinoma: comparison of mangafodipir trisodium and gadopentetate dimeglumine contrast agents.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Contrast Media; Diagnosis, Differential; | 2004 |
Biliary atresia: feasibility of mangafodipir trisodium-enhanced MR cholangiography for evaluation.
Topics: Biliary Atresia; Cholangiography; Contrast Media; Edetic Acid; Feasibility Studies; Female; Humans; | 2005 |
Detection of liver metastases from adenocarcinoma of the colon and pancreas: comparison of mangafodipir trisodium-enhanced liver MRI and whole-body FDG PET.
Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Contrast Media; Edetic Acid; Female; Fluorodeoxygluc | 2005 |
Detection of liver metastases from gastrointestinal cancer: comparision of high resolution MnDPDP enhanced MRI and FDG-PET.
Topics: Adenocarcinoma; Adult; Aged; Contrast Media; Edetic Acid; Female; Fluorodeoxyglucose F18; Gastrointe | 2005 |
[Mangafodipir trisodium-enhanced magnetic resonance cholangiography for detection of bile leaks].
Topics: Abdominal Injuries; Adolescent; Adult; Aged; Bile; Bile Duct Diseases; Biliary Fistula; Cholecystect | 2006 |
Mangafodipir trisodium-enhanced MR imaging of pancreatic disease.
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Edetic Acid; Female; Humans; Image Enhancement; Imag | 2006 |
Diagnostic accuracy of portal-phase CT and MRI with mangafodipir trisodium in detecting liver metastases from colorectal carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Contrast Media; Edetic Acid; Female; Humans; L | 2006 |
15N nuclear magnetic resonance studies of acid-base properties of pyridoxal-5'-phosphate aldimines in aqueous solution.
Topics: Aldehydes; Hydrogen Bonding; Hydrogen-Ion Concentration; Imines; Magnetic Resonance Spectroscopy; Mo | 2007 |
Capillary electrophoretic screening for the inhibition of homocysteine thiolactone-induced protein oligomerization.
Topics: Animals; Cations; Cattle; Cytochromes c; Dose-Response Relationship, Drug; Electrophoresis, Capillar | 2007 |
Detection of colorectal hepatic metastases using MnDPDP MR imaging and diffusion-weighted imaging (DWI) alone and in combination.
Topics: Aged; Colorectal Neoplasms; Contrast Media; Diffusion Magnetic Resonance Imaging; Edetic Acid; Femal | 2008 |
NMR studies of 1H resonances in the 10-18-ppm range for cytosolic aspartate aminotransferase.
Topics: Amino Acid Sequence; Animals; Aspartate Aminotransferases; Base Sequence; Cloning, Molecular; Cytoso | 1994 |
NMR studies of 1H resonances in the 10-18-ppm range for aspartate aminotransferase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartate Aminotransferases; Escherichia coli; Histidine; | 1994 |
Hepatobiliary contrast material: a magic bullet for sensitivity and specificity?
Topics: Contrast Media; Edetic Acid; Humans; Liver Neoplasms; Magnetic Resonance Imaging; Pyridoxal Phosphat | 1993 |
Mangafodipir trisodium injection, a new contrast medium for magnetic resonance imaging: detection and quantitation of the parent compound MnDPDP and metabolites in human plasma by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Contrast Media; Edetic Acid; Humans; Magnetic Resonance Imagin | 1997 |
High-performance liquid chromatography determination of total pyridoxal in human plasma.
Topics: Administration, Oral; Adult; Biological Availability; Chromatography, High Pressure Liquid; Female; | 1997 |
Mangafodipir trisodium (MnDPDP)-enhanced magnetic resonance imaging of the liver and pancreas.
Topics: Adenocarcinoma; Adenoma, Islet Cell; Adipose Tissue; Adult; Aged; Aged, 80 and over; Blood-Brain Bar | 1998 |
A simple, sensitive and reproducible assay for pyridoxal 5'-phosphate and 4-pyridoxic acid in human plasma.
Topics: Aged; Chromatography, High Pressure Liquid; Female; Humans; Male; Pyridoxal Phosphate; Pyridoxic Aci | 1999 |
Concomitant blockade of P2X-receptors and ecto-nucleotidases by P2-receptor antagonists: functional consequences in rat vas deferens.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphatases; Adenosine Triphosphate; | 1999 |
Sequential use of gadolinium chelate and mangafodipir trisodium for the assessment of focal liver lesions: initial observations.
Topics: Adult; Aged; Contrast Media; Diagnosis, Differential; Edetic Acid; Female; Focal Nodular Hyperplasia | 2000 |
Determination of vitamin B(6) in cooked sausages.
Topics: Acetonitriles; Buffers; Chromatography, High Pressure Liquid; Meat Products; Phosphates; Pyridoxal; | 2001 |
Clinical and cost effectiveness of a new hepatocellular MRI contrast agent, mangafodipir trisodium, in the preoperative assessment of liver resectability.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Contrast Media; Cost-Benefit Analysis; Edetic Acid; Fema | 2001 |
Liver lesions: manganese-enhanced MR and dual-phase helical CT for preoperative detection and characterization comparison with receiver operating characteristic analysis.
Topics: Adult; Aged; Chi-Square Distribution; Contrast Media; Edetic Acid; Female; Humans; Liver Diseases; M | 2002 |
Enzymatic characterization of a recombinant isoform hybrid of glutamic acid decarboxylase (rGAD67/65) expressed in yeast.
Topics: Catalysis; Enzyme Stability; gamma-Aminobutyric Acid; Gene Expression; Glutamate Decarboxylase; Glut | 2002 |
[MR imaging of pancreatic lesions with Mn-DPDP. A histopathologic correlation].
Topics: Ampulla of Vater; Biopsy, Needle; Common Bile Duct Neoplasms; Contrast Media; Edetic Acid; Humans; I | 2002 |
Hepatic MR imaging with Mn-DPDP: safety, image quality, and sensitivity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Edetic Acid; Female; Humans; Liver; Live | 1992 |
Highly sensitive determination of PLP in human plasma with HPLC method.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Female; Fluorescence; Humans; Hydrogen-Ion | 1990 |