Page last updated: 2024-08-08 00:16:43
Serine/threonine-protein kinase mTOR
A serine/threonine-protein kinase mTOR that is encoded in the genome of mouse. [OMA:Q9JLN9, PRO:DNx]
Synonyms
EC 2.7.11.1;
FK506-binding protein 12-rapamycin complex-associated protein 1;
FKBP12-rapamycin complex-associated protein;
Mammalian target of rapamycin;
mTOR;
Mechanistic target of rapamycin;
Rapamycin target protein 1;
RAPT1
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| sirolimus | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| buparlisib | Mus musculus (house mouse) | IC50 | 0.8320 | 1 | 1 |
| torin 1 | Mus musculus (house mouse) | IC50 | 0.0020 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| torin 1 | Mus musculus (house mouse) | EC50 | 0.0020 | 1 | 1 |
| torin 2 | Mus musculus (house mouse) | EC50 | 0.0002 | 1 | 1 |