diphenyltin profile

Diphenyltin, also known as diphenylstannane, is an organotin compound with the formula (C6H5)2SnH2. It is a colorless solid that is used as a reagent in organic synthesis. Diphenyltin is a versatile starting material for the preparation of other organotin compounds, including diphenyltin dichloride and diphenyltin oxide. Diphenyltin has been studied for its potential applications in areas such as catalysis, polymerization, and medicine. For example, diphenyltin dichloride has been shown to be an effective catalyst for the polymerization of various monomers. Diphenyltin compounds are also known to exhibit antimicrobial and anti-inflammatory activities, and have been investigated for their potential use in the treatment of various diseases. However, organotin compounds, including diphenyltin, have also been shown to have toxic effects, particularly in aquatic environments. Therefore, the use of diphenyltin compounds must be carefully considered and managed to minimize potential risks.'

ID Source	ID
PubMed CID	70535
MeSH ID	M0175563

Synonym
C0697
diphenyltin
nsc162819
nsc-162819
6381-06-2
tin, diphenyl-
NCI60_001216
stannane, diphenyl-
brn 4933262
4-16-00-01590 (beilstein handbook reference)
diphenylzinn
diphenyltin(iv)
Q4162487

Excerpt	Relevance	Reference
"5 and relatively high biomass dosage in mineral salt medium improved TPT degradation."	( Triphenyltin biodegradation and intracellular material release by Brevibacillus brevis. Gao, J; Ma, Y; Peng, H; Tang, L; Ye, J; Yin, H; Zhao, H, 2014)	0.4

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	3 (8.82)	18.2507
2000's	16 (47.06)	29.6817
2010's	11 (32.35)	24.3611
2020's	4 (11.76)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	35 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
chlorine chloride : A halide anion formed when chlorine picks up an electron to form an an anion.	2.49	2	halide anion; monoatomic chlorine	cofactor; Escherichia coli metabolite; human metabolite
ciprofloxacin Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.. ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.	7.25	1	aminoquinoline; cyclopropanes; fluoroquinolone antibiotic; N-arylpiperazine; quinolinemonocarboxylic acid; quinolone antibiotic; quinolone; zwitterion	antibacterial drug; antiinfective agent; antimicrobial agent; DNA synthesis inhibitor; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; environmental contaminant; topoisomerase IV inhibitor; xenobiotic
serine Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.. serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.	2.04	1	L-alpha-amino acid; proteinogenic amino acid; serine family amino acid; serine zwitterion; serine	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
carbostyril Quinolones: A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.. quinolin-2(1H)-one : A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.	3.14	1	monohydroxyquinoline; quinolone	bacterial xenobiotic metabolite
1,2-dipalmitoylphosphatidylcholine 1,2-Dipalmitoylphosphatidylcholine: Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.	2.01	1
triphenyltin chloride triphenyltin chloride: see also triphenyltin acetate, triphenyltin hydroxide. fentin chloride : An organotin compound that is triphenylstannane in which the hydrogen attached to tin is replaced by a chloro group. A fungicide used to control blights on potatoes, leaf spot diseases on sugar beet and anthracnose on beans.	2.48	2	chlorine molecular entity; organotin compound	antifungal agrochemical; immunosuppressive agent
dibutyldichlorotin [no description available]	2.72	3
tetrabutyltin [no description available]	2.15	1
dimethyltin [no description available]	2.72	3	organotin compound
diethyllead diethyllead: environmental degradation product of tetraethyllead	2.13	1
mono-n-butyltin [no description available]	3.03	4
pyoverdin pyoverdin: a partly cyclic octapeptide linked to a chromophore, derived from 2,3-diamino-6,7-dihydroxyquinoline, which confers color and fluorescence to the molecule; yellow-green pigment produced by Pseudomonas aeruginosa; pyoverdin Pf from P. fluorescens; structure has been determined	2.01	1
lead Lead: A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb.	2.13	1	carbon group element atom; elemental lead; metal atom	neurotoxin
tin [no description available]	2.76	3	carbon group element atom; elemental tin; metal atom	micronutrient
triphenyltin triphenyltin: triphenyltin derivatives widely used as pesticides; all of first source is triphenyltin cpds	9.39	20
trimethyltin trimethyltin : An organotin compound that consists of stannane in which three of the four hydrogens are substituted by methyl groups.	1.97	1
cytochrome c-t Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.	2.08	1
phosphatidylcholines Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.	2.01	1	1,2-diacyl-sn-glycero-3-phosphocholine
inosine [no description available]	2.08	1	inosines; purines D-ribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
cyclic imp Cyclic IMP: Inosine cyclic 3',5'-(hydrogen phosphate). An inosine nucleotide which acts as a mild inhibitor of the hydrolysis of cyclic AMP and cyclic GMP and as an inhibitor of cat heart cyclic AMP phosphodiesterase.. 3',5'-cyclic IMP : A 3',5'-cyclic purine nucleotide having hypoxanthine as the nucleobase.	2.08	1	3',5'-cyclic purine nucleotide; nucleoside 3',5'-cyclic phosphate	mammalian metabolite; Saccharomyces cerevisiae metabolite

Condition	Relationship Strength	Studies
Breast Cancer [description not available]	3.14	1
Malignant Melanoma [description not available]	3.14	1
Breast Neoplasms Tumors or cancer of the human BREAST.	3.14	1
Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)	3.14	1
Infection [description not available]	2.25	1
Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases.	2.25	1
Benign Neoplasms [description not available]	2.47	2
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	2.47	2
Dehydration The condition that results from excessive loss of water from a living organism.	2.05	1
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.71	3
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	2.03	1
Aneuploid [description not available]	1.97	1

diphenyltin

Cross-References

Synonyms (13)

Research Excerpts

Dosage Studied

Research

Studies (34)

Market Indicators

Research Demand Index: 27.09

Study Types