loperamide has been researched along with Sensitivity and Specificity in 7 studies
Loperamide: One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
loperamide : A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In children who are older than 3 y with no/minimal dehydration, loperamide may be a useful adjunct to oral rehydration and early refeeding." | 8.84 | Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis. ( Cummings, P; Grossman, DC; Li, ST, 2007) |
| " In children who are older than 3 y with no/minimal dehydration, loperamide may be a useful adjunct to oral rehydration and early refeeding." | 4.84 | Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis. ( Cummings, P; Grossman, DC; Li, ST, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Livingston, KE | 1 |
| Mahoney, JP | 1 |
| Manglik, A | 1 |
| Sunahara, RK | 1 |
| Traynor, JR | 1 |
| Hua, S | 1 |
| Johansen, SS | 1 |
| Jensen, JL | 1 |
| Streel, B | 1 |
| Ceccato, A | 1 |
| Klinkenberg, R | 1 |
| Hubert, P | 1 |
| Li, ST | 1 |
| Grossman, DC | 1 |
| Cummings, P | 1 |
| Buzi, F | 1 |
| Corna, A | 1 |
| Pilotta, A | 1 |
| Negrini, F | 1 |
| Lombardi, A | 1 |
| Re, T | 1 |
| Ambrosi, B | 1 |
| He, H | 1 |
| Sadeque, A | 1 |
| Erve, JC | 1 |
| Wood, AJ | 1 |
| Hachey, DL | 1 |
1 review available for loperamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis.
Topics: Age Factors; Child; Child, Preschool; Dehydration; Diarrhea; Humans; Infant; Loperamide; Models, Sta | 2007 |
1 trial available for loperamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Loperamide test: a simple and highly specific screening test for hypercortisolism in children and adolescents.
Topics: Adolescent; Adrenocortical Hyperfunction; Adult; Child; Dexamethasone; Female; Glucocorticoids; Huma | 1997 |
5 other studies available for loperamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor.
Topics: Allosteric Regulation; Allosteric Site; Biosensing Techniques; Biotin; Humans; Interferometry; Ligan | 2018 |
Comparison of in vitro dialysis release methods of loperamide-encapsulated liposomal gel for topical drug delivery.
Topics: Administration, Topical; Antidiarrheals; Dialysis; Diffusion; Drug Evaluation, Preclinical; Gels; Li | 2014 |
Liquid chromatography-tandem mass spectrometry determination of loperamide and its main metabolite desmethylloperamide in biological specimens and application to forensic cases.
Topics: Antidiarrheals; Chromatography, High Pressure Liquid; Humans; Loperamide; Mass Spectrometry; Reprodu | 2004 |
Validation of a liquid chromatographic-tandem mass spectrometric method for the determination of loperamide in human plasma.
Topics: Antidiarrheals; Chromatography, Liquid; Humans; Loperamide; Mass Spectrometry; Reproducibility of Re | 2005 |
Quantitation of loperamide and N-demethyl-loperamide in human plasma using electrospray ionization with selected reaction ion monitoring liquid chromatography-mass spectrometry.
Topics: Adult; Calibration; Chromatography, High Pressure Liquid; Humans; Loperamide; Reproducibility of Res | 2000 |