Page last updated: 2024-08-07 20:32:27
Probable maltase-glucoamylase 2
A protein that is a translation product of the MGAM2 gene in human. [PRO:DNx, UniProtKB:Q2M2H8]
Synonyms
Maltase-glucoamylase (alpha-glucosidase) pseudogene
Research
Bioassay Publications (13)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (92.31) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
Compounds (20)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 2,4-thiazolidinedione | Homo sapiens (human) | IC50 | 0.5400 | 1 | 1 |
| methyl acetoacetate | Homo sapiens (human) | IC50 | 19.0000 | 1 | 1 |
| diethyl malonate | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| 1-deoxynojirimycin | Homo sapiens (human) | IC50 | 115.7500 | 2 | 2 |
| acarbose | Homo sapiens (human) | IC50 | 504.7560 | 10 | 10 |
| (-)-catechin | Homo sapiens (human) | IC50 | 53.8000 | 1 | 1 |
| terphenyllin | Homo sapiens (human) | IC50 | 4.7900 | 1 | 1 |
| terphenyllin | Homo sapiens (human) | Ki | 1.5000 | 1 | 1 |
| 3-hydroxyterphenyllin | Homo sapiens (human) | IC50 | 11.3000 | 1 | 1 |
| 2-(Benzotriazol-1-yl)-1-(4-bromophenyl)ethanone | Homo sapiens (human) | IC50 | 2.7900 | 1 | 1 |
| trisindoline | Homo sapiens (human) | IC50 | 5.9000 | 1 | 1 |
| quercetin | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| mangostin | Homo sapiens (human) | IC50 | 5.7000 | 1 | 1 |
| mangostin | Homo sapiens (human) | Ki | 7.3000 | 1 | 1 |
| 7,8-dihydroxy-4-methylcoumarin | Homo sapiens (human) | IC50 | 52.0000 | 1 | 1 |
| gamma-mangostin | Homo sapiens (human) | IC50 | 1.7000 | 1 | 1 |
| gamma-mangostin | Homo sapiens (human) | Ki | 1.4000 | 1 | 1 |
| beta-Mangostin | Homo sapiens (human) | IC50 | 22.6000 | 1 | 1 |
| 9-Hydroxycalabaxanthone | Homo sapiens (human) | IC50 | 11.4000 | 1 | 1 |
| sch 725680 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| aspernolide a | Homo sapiens (human) | IC50 | 47.3300 | 1 | 1 |
| aspulvinone E | Homo sapiens (human) | IC50 | 400.0000 | 1 | 1 |
| pinophilin b | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
Enables
This protein enables 3 target(s):
| Target | Category | Definition |
|---|---|---|
| glucan 1,4-alpha-glucosidase activity | molecular function | Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. [EC:3.2.1.3] |
| carbohydrate binding | molecular function | Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. [GOC:mah] |
| alpha-1,4-glucosidase activity | molecular function | Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. [EC:3.2.1.20] |
Located In
This protein is located in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| membrane | cellular component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
Involved In
This protein is involved in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| carbohydrate metabolic process | biological process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. [GOC:mah, ISBN:0198506732] |