Proteins > large T antigen
Page last updated: 2024-08-07 13:50:48

large T antigen

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (119)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
3-hydroxyanthranilic acidBetapolyomavirus macacaeIC5020.090010
hydroquinoneBetapolyomavirus macacaeIC507.760010
n-acetylserotoninBetapolyomavirus macacaeIC5021.670010
2-aminofluoreneBetapolyomavirus macacaeIC503.520010
pyrithioneBetapolyomavirus macacaeIC5030.260010
p-chloromercuribenzoic acidBetapolyomavirus macacaeIC501.270010
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diolBetapolyomavirus macacaeIC5020.250010
aurintricarboxylic acidBetapolyomavirus macacaeIC501.930010
bithionolBetapolyomavirus macacaeIC5035.700010
disulfiramBetapolyomavirus macacaeIC5010.730010
ebselenBetapolyomavirus macacaeIC5013.910010
erythrosineBetapolyomavirus macacaeIC5013.040010
ethacrynic acidBetapolyomavirus macacaeIC50100.000010
hexachloropheneBetapolyomavirus macacaeIC5034.500010
mesalamineBetapolyomavirus macacaeIC5019.100010
masoprocolBetapolyomavirus macacaeIC5021.860010
sb 202190Betapolyomavirus macacaeIC504.870010
n-isopropyl-n-phenyl-4-phenylenediamineBetapolyomavirus macacaeIC509.010010
5H-dibenzo[b,f]azepineBetapolyomavirus macacaeIC5014.340010
2,3-dimercaptosuccinic acidBetapolyomavirus macacaeIC5075.870010
lithocholic acidBetapolyomavirus macacaeIC5026.100010
hematoxylinBetapolyomavirus macacaeIC504.660010
2-hydroxyacetanilideBetapolyomavirus macacaeIC506.200010
4,4'-bisphenol fBetapolyomavirus macacaeIC5070.100010
5-hydroxyindoleBetapolyomavirus macacaeIC5080.220010
1,2-benzisothiazoline-3-oneBetapolyomavirus macacaeIC5032.300010
u 0521Betapolyomavirus macacaeIC5030.900010
N-[4-(dimethylamino)phenyl]-3,4,5-trimethoxybenzamideBetapolyomavirus macacaeIC506.340010
fenoldopam mesylateBetapolyomavirus macacaeIC50100.000010
2,2'-dipyridyl disulfideBetapolyomavirus macacaeIC50100.000010
ay-20694Betapolyomavirus macacaeIC50100.000010
thioxoloneBetapolyomavirus macacaeIC5019.020010
jatrorrhizineBetapolyomavirus macacaeIC5010.120010
4-(4-hydroxyphenyl)-2-butanolBetapolyomavirus macacaeIC5025.380010
catechinBetapolyomavirus macacaeIC5011.410010
Serotonin hydrochlorideBetapolyomavirus macacaeIC5041.310010
qlt 0267Betapolyomavirus macacaeIC5011.990010
2-hydroxyestradiolBetapolyomavirus macacaeIC50100.000010
nsc 95397Betapolyomavirus macacaeIC5026.630010
taxifolinBetapolyomavirus macacaeIC5031.960010
(R)-norlaudanosolineBetapolyomavirus macacaeIC509.060010
resveratrolBetapolyomavirus macacaeIC5026.200010
1-phenyl-4-pyrazololBetapolyomavirus macacaeIC504.710010
trans-4-coumaric acidBetapolyomavirus macacaeIC5018.890010
3-Hydroxy-1-(4-hydroxyphenyl)-1-propanoneBetapolyomavirus macacaeIC5028.790010
(2-amino-5-methyl-3-thiophenyl)-thiophen-2-ylmethanoneBetapolyomavirus macacaeIC5051.800010
5-hydroxy-N,N-dimethyl-2-phenyl-3-benzofurancarboxamideBetapolyomavirus macacaeIC5046.560010
4-[4-[(1-cyclopentyl-5-tetrazolyl)-pyridin-4-ylmethyl]-1-piperazinyl]phenolBetapolyomavirus macacaeIC505.610010
1-(3,4-dihydroxyphenyl)-2-[[5-(2-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanoneBetapolyomavirus macacaeIC5014.690010
2-methoxy-6-[[(1-propyl-5-benzimidazolyl)amino]methyl]phenolBetapolyomavirus macacaeIC5022.110010
3,3',4,5'-tetrahydroxystilbeneBetapolyomavirus macacaeIC5016.350010
N-[4-(diethylamino)phenyl]-2-furancarboxamideBetapolyomavirus macacaeIC505.010010
caffeic acidBetapolyomavirus macacaeIC507.300010
N4,N4-dimethyl-N1-(4-nitro-1,1-dioxo-2,5-dihydrothiophen-3-yl)benzene-1,4-diamineBetapolyomavirus macacaeIC505.710010
N-[4-(1-azepanyl)phenyl]-2-chloroacetamideBetapolyomavirus macacaeIC5018.890010
acetic acid [4-[(4-hydroxyanilino)-oxomethyl]-2-methoxyphenyl] esterBetapolyomavirus macacaeIC506.120010
2-(2,5-dimethylphenyl)-3H-benzimidazol-5-amineBetapolyomavirus macacaeIC5083.720010
N-(4-hydroxyphenyl)-8-quinolinesulfonamideBetapolyomavirus macacaeIC507.360010
4-[[4-bromo-5-(4-morpholinyl)-2-furanyl]methylideneamino]phenolBetapolyomavirus macacaeIC5021.730010
6,7-dimethyl-2H-pyrazolo[3,4-b]quinolin-3-amineBetapolyomavirus macacaeIC5030.270010
4-[(4-chloro-1-naphthalenyl)oxy]-5-methoxy-2-(2-pyridinyl)pyrimidineBetapolyomavirus macacaeIC507.480010
6-fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-oneBetapolyomavirus macacaeIC5013.090010
1,4-benzoquinone guanylhydrazone thiosemicarbazoneBetapolyomavirus macacaeIC5013.730010
chlorogenic acidBetapolyomavirus macacaeIC5014.670010
6-[[(4-chlorophenyl)thio]methyl]-2-phenyl-1,7-dihydropyrazolo[3,4-b]pyridine-3,4-dioneBetapolyomavirus macacaeIC50100.000010
2-[3-(2-furanylmethyl)-2,4-dioxo-6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-b]pyrimidin-1-yl]acetamideBetapolyomavirus macacaeIC5033.000010
N-[(tert-butylamino)-oxomethyl]-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamideBetapolyomavirus macacaeIC5021.200010
3-[[(2,3-dimethylanilino)-sulfanylidenemethyl]amino]-1H-indole-2-carboxylic acid ethyl esterBetapolyomavirus macacaeIC5035.050010
thiocyanic acid [2-(1-naphthalenyl)-2-oxoethyl] esterBetapolyomavirus macacaeIC5020.650010
2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-oneBetapolyomavirus macacaeIC5026.070010
2,8-dimercapto-6-hydroxypurineBetapolyomavirus macacaeIC5027.200010
3-[(4-chlorophenyl)thio]-1-[4-(4-hydroxyphenyl)-1-piperazinyl]-1-propanoneBetapolyomavirus macacaeIC506.740010
[4-(4-hydroxyphenyl)-1-piperazinyl]-[2-methoxy-4-(methylthio)phenyl]methanoneBetapolyomavirus macacaeIC505.950010
N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamideBetapolyomavirus macacaeIC5013.650010
N-(3-pyridinylmethyl)-1,3-benzodioxol-5-amineBetapolyomavirus macacaeIC5025.420010
1-(4-hydroxyphenyl)-3-(3-methoxyphenyl)thioureaBetapolyomavirus macacaeIC505.640010
N-(4-anilinophenyl)-3-(hydroxymethyl)-1-piperidinecarbothioamideBetapolyomavirus macacaeIC508.160010
1-[4-(dimethylamino)phenyl]-3-[4-(4-morpholinyl)anilino]pyrrolidine-2,5-dioneBetapolyomavirus macacaeIC5012.880010
fusidic acidBetapolyomavirus macacaeIC5020.420010
2-[8-(6-amino-1H-benzimidazol-2-yl)octyl]-3H-benzimidazol-5-amineBetapolyomavirus macacaeIC5018.710010
4-[4-[[1-(2-methylbutan-2-yl)-5-tetrazolyl]-(6-quinolinyl)methyl]-1-piperazinyl]phenolBetapolyomavirus macacaeIC5034.640010
4-[4-[(1-tert-butyl-5-tetrazolyl)-pyridin-4-ylmethyl]-1-piperazinyl]phenolBetapolyomavirus macacaeIC5013.890010
N-[4-(dimethylamino)phenyl]-2-(1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)acetamideBetapolyomavirus macacaeIC5029.630010
N-[[4-(dimethylamino)phenyl]methyl]-1-ethyl-5-benzimidazolamineBetapolyomavirus macacaeIC5015.800010
N-cyclohexyl-2-(5-methyl-2-furanyl)-3-imidazo[1,2-a]pyrimidinamineBetapolyomavirus macacaeIC5025.950010
6-amino-5-cyano-4-(2-fluorophenyl)-2-sulfanylidene-3,4-dihydro-1H-pyridine-3-carboxamideBetapolyomavirus macacaeIC5059.960010
1-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(2,4,6-trimethylphenyl)thioureaBetapolyomavirus macacaeIC5019.140010
2-[[3-(3-oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acidBetapolyomavirus macacaeIC5013.220010
sb 415286Betapolyomavirus macacaeIC5055.430010
1-(2,6-dimethylphenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]thioureaBetapolyomavirus macacaeIC5014.650010
isovitexinBetapolyomavirus macacaeIC5021.430010
2-[2,5-diethoxy-4-(4-morpholinyl)anilino]-1-(4-methyl-1-piperidinyl)-1-propanoneBetapolyomavirus macacaeIC5017.140010
N,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamideBetapolyomavirus macacaeIC5013.270010
luteolinBetapolyomavirus macacaeIC5011.900010
esculetinBetapolyomavirus macacaeIC5025.940010
polydatinBetapolyomavirus macacaeIC5011.180010
heliparvifolineBetapolyomavirus macacaeIC5019.960010
indocyanine greenBetapolyomavirus macacaeIC502.100010
8-(2-chlorophenyl)-3-(4-ethoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrileBetapolyomavirus macacaeIC5017.380010
salazinic acidBetapolyomavirus macacaeIC5017.490010
ag 538Betapolyomavirus macacaeIC500.820010
tyrphostin ag 555Betapolyomavirus macacaeIC5020.970010
tyrphostin ag-494Betapolyomavirus macacaeIC5013.110010
tyrphostin b44Betapolyomavirus macacaeIC507.280010
ag-490Betapolyomavirus macacaeIC5014.610010
ag 183Betapolyomavirus macacaeIC5019.790010
4-[4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl hexopyranosideBetapolyomavirus macacaeIC5021.320010
urolithin bBetapolyomavirus macacaeIC5038.760010
2',3,4-trihydroxychalconeBetapolyomavirus macacaeIC5017.360010
1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-6-yl]hexitolBetapolyomavirus macacaeIC505.230010
2-hydroxyapomorphine, (r)-isomerBetapolyomavirus macacaeIC509.430010
5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-3-yl 6-O-(6-deoxyhexopyranosyl)hexopyranosideBetapolyomavirus macacaeIC5017.260010
tanninsBetapolyomavirus macacaeIC500.160010
quercetinBetapolyomavirus macacaeIC5016.140010
xi-3-Hydroxy-5-phenylpentanoic acid O-beta-D-GlucopyranosideBetapolyomavirus macacaeIC5057.570010
thimerosalBetapolyomavirus macacaeIC5032.720010
4'-epichaetoviridin ABetapolyomavirus macacaeIC5043.960010
fusidate sodiumBetapolyomavirus macacaeIC5031.570010
catechinBetapolyomavirus macacaeIC508.640010

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
thioxoloneBetapolyomavirus macacaeEC5031.180010
nsc 95397Betapolyomavirus macacaeEC5028.240010
(2-amino-5-methyl-3-thiophenyl)-thiophen-2-ylmethanoneBetapolyomavirus macacaeEC5035.790010
N-[4-(1-azepanyl)phenyl]-2-chloroacetamideBetapolyomavirus macacaeEC5047.090010
2-(2,5-dimethylphenyl)-3H-benzimidazol-5-amineBetapolyomavirus macacaeEC5050.000010
4-[(4-chloro-1-naphthalenyl)oxy]-5-methoxy-2-(2-pyridinyl)pyrimidineBetapolyomavirus macacaeEC5013.740010
6-fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-oneBetapolyomavirus macacaeEC5014.550010
1,4-benzoquinone guanylhydrazone thiosemicarbazoneBetapolyomavirus macacaeEC500.100010
2-[3-(2-furanylmethyl)-2,4-dioxo-6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-b]pyrimidin-1-yl]acetamideBetapolyomavirus macacaeEC5050.000010
N-[(tert-butylamino)-oxomethyl]-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamideBetapolyomavirus macacaeEC5050.000010
2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-oneBetapolyomavirus macacaeEC5014.740010
3-[(4-chlorophenyl)thio]-1-[4-(4-hydroxyphenyl)-1-piperazinyl]-1-propanoneBetapolyomavirus macacaeEC5014.580010
N-(4-anilinophenyl)-3-(hydroxymethyl)-1-piperidinecarbothioamideBetapolyomavirus macacaeEC5050.000010
N-cyclohexyl-2-(5-methyl-2-furanyl)-3-imidazo[1,2-a]pyrimidinamineBetapolyomavirus macacaeEC5050.000010
1-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(2,4,6-trimethylphenyl)thioureaBetapolyomavirus macacaeEC5015.880010
1-(2,6-dimethylphenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]thioureaBetapolyomavirus macacaeEC5045.780010
N,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamideBetapolyomavirus macacaeEC5030.400010
luteolinBetapolyomavirus macacaeEC5047.930010
tyrphostin ag-494Betapolyomavirus macacaeEC5050.000010
tyrphostin b44Betapolyomavirus macacaeEC5050.000010
2',3,4-trihydroxychalconeBetapolyomavirus macacaeEC5026.260010
quercetinBetapolyomavirus macacaeEC5050.000010
4'-epichaetoviridin ABetapolyomavirus macacaeEC5050.000010