Compounds > phorate
Page last updated: 2024-09-20

phorate

Description

Phorate: A cholinesterase inhibitor that is used as an insecticide. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

phosphatidylcholine O-34:2 : A glycerophosphocholine that is an alkyl,acyl-sn-glycero-3-phosphocholine in which the alkyl or acyl groups at positions 1 and 2 contain a total of 34 carbons and 2 double bonds. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID4790
CHEMBL ID510014
CHEBI ID38764
SCHEMBL ID26312
MeSH IDM0016628

Synonyms (126)

Synonym
phosphorodithioic acid, o,o-diethyl s-[(ethylthio)methyl] ester
american cyanamid 3,911
DIVK1C_006488
KBIO1_001432
SPECTRUM_001801
o,o-diethyl s-ethylmercaptomethyl dithiophosphonate
foraat [dutch]
vuagt 182
methanethiol, (ethylthio)-, s-ester with o,o-diethyl phosphorodithioate
o,o-diethyl s-ethylthiomethyl thiothionophosphate
rcra waste number p094
einecs 206-052-2
o,o-diethyl ethylthiomethyl phosphorodithioate
hsdb 1183
brn 1708517
epa pesticide chemical code 057201
geomet
phorat [german]
agrimet
caswell no. 660
phorate-10g
ei3911
o,o-diethyl s-ethylthiomethyl dithiophosphonate
methanethiol, (ethylthio)-, s-ester with o,o-diethylphosphorodithioate
vegfru foratox
phosphorodithioic acid, o,o-diethyl s-(ethylthio)methyl ester
vegfru
l 11/6
o,o-diethyl-s-(ethylthio-methyl)-dithiofosfaat [dutch]
granutox
ent 24,042
experimental insecticide 3911
timet
o,o-diaethyl-s-(aethylthio-methyl)-dithiophosphat [german]
ac 3911
rcra waste no. p094
o,o-dietil-s-(etiltio-metil)-ditiofosfato [italian]
phorate [ansi:bsi:iso]
thimet 10-g
ai3-24042
ccris 2747
dithiophosphate de o,o-diethyle et d'ethylthiomethyle [french]
thimenox
o,o-diethyl-s-((ethylthio)methyl)phosphorodithioate
thimet 10g
thimet 10 g
SPECTRUM5_001942
BSPBIO_002311
phosphorodithioic acid, o,o-diethyl s-((ethylthio)methyl) ester
o,o-diethyl s-ethylmercaptomethyl dithiophosphate
o,o-diethyl s-[(ethylsulfanyl)methyl] phosphorodithioate
o,o-diethyl s-(ethylthio)methyl phosphorodithioate
o,o-diethyl s-[(ethylsulfanyl)methyl] dithiophosphate
298-02-2
thimet
phorate
CHEBI:38764 ,
NCGC00163889-01
KBIOGR_001031
KBIO3_001811
KBIO2_007428
KBIOSS_002294
KBIO2_004860
KBIO2_002292
SPECTRUM4_000656
SPBIO_001680
SPECTRUM2_001860
SPECTRUM3_000816
SPECPLUS_000392
NCGC00163889-02
o,o-diethyl-s-ethylthiomethylphosphorodithioate
vegfru foratox.
CHEMBL510014
NCGC00163889-03
C18690
tox21_300398
cas-298-02-2
NCGC00254280-01
dtxcid2012459
dtxsid4032459 ,
CCG-39364
o,o-diaethyl-s-(aethylthio-methyl)-dithiophosphat
o,o-diethyl-s-(ethylthio-methyl)-dithiofosfaat
phorat
3w54x3w9iv ,
foraat
dithiophosphate de o,o-diethyle et d'ethylthiomethyle
o,o-dietil-s-(etiltio-metil)-ditiofosfato
unii-3w54x3w9iv
o,o-diethyl s-(ethylthiomethyl) phosphorodithioate
thimet g
o,o-diethyl s-ethylthiomethyl dithiophosphate
phorate 10g
phosphatidylcholine o-34:2
AKOS015898767
SCHEMBL26312
o,o-diethyl s-((ethylthio)methyl) phosphorodithioate
o,o-diethyl s-ethylthiomethyl phosphorodithioate
ent-24042
phorate [mi]
ei-3911
phorate [hsdb]
phorate [iso]
forate
o,o-diethyl s-[(ethylthio)methyl] phosphorodithioate
volphor
methanethiol, (ethylthio)-, s-ester with o,o-diethyl phosphorodithioic acid
BULVZWIRKLYCBC-UHFFFAOYSA-N
o,o-diethyl s-[(ethylsulfanyl)methyl] dithiophosphate #
thimate
phorate, pestanal(r), analytical standard
phorate 100 microg/ml in cyclohexane
phorate 10 microg/ml in cyclohexane
J-017647
o,o-diethyl s-(ethylthio)methyl phosphorodithioic acid
phosphorodithioate, o,o-diethyl s-((ethylthio)methyl) ester
o,o-diethyl s-[(ethylsulfanyl)methyl] dithiophosphoric acid
o,o-diethyl s-[(ethylsulphanyl)methyl] dithiophosphate
o,o-diethyl s-ethylmercaptomethyl dithiophosphoric acid
o,o-diethyl s-[(ethylsulphanyl)methyl] dithiophosphoric acid
phorate 1000 microg/ml in methanol
Q421197
diethoxy-(ethylsulfanylmethylsulfanyl)-sulfanylidene-lambda5-phosphane
phorate 1000 microg/ml in acetone
phorate 100 microg/ml in methanol
phorate 1000 microg/ml in toluene

Research Excerpts

Overview

ExcerptReference
"Phorate is a systemic insecticide used to eradicate mites, insects, and nematodes. "( Anil, AG; Kumar, V; Ramamurthy, PC; Romero, R; Singh, J; Singh, S, 2022)
"Phorate is a highly toxic agricultural pesticide currently in use throughout the world. "( Babin, MC; Jett, DA; McGarry, KG; Moyer, RA; Platoff, GE; Yeung, DT, 2018)

Roles (4)

RoleDescription
EC 3.1.1.7 (acetylcholinesterase) inhibitorAn EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
EC 3.1.1.8 (cholinesterase) inhibitorAn EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
acaricideA substance used to destroy pests of the subclass Acari (mites and ticks).
agrochemicalAn agrochemical is a substance that is used in agriculture or horticulture.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
organic thiophosphate
organothiophosphate insecticide
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (5)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
acetylcholinesteraseHomo sapiens (human)Potency63.26090.002541.796015,848.9004AID1347395; AID1347398
GLI family zinc finger 3Homo sapiens (human)Potency1.02630.000714.592883.7951AID1259392
estrogen nuclear receptor alphaHomo sapiens (human)Potency30.63790.000229.305416,493.5996AID743079
thyroid stimulating hormone receptorHomo sapiens (human)Potency27.30600.001628.015177.1139AID1224843; AID1224895
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency86.34920.000627.21521,122.0200AID720636
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (52)

Assay IDTitleYearJournalArticle
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1081325Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested tomato plants plots assessed as nematode population per cm3 soil measured 110 days post dose following field application at 1 kg of active ingredient/hectare (Rvb = 1.38 to2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081367Cmax in Cicer arietinum (chickpea) shoots measured 45 days post dose following field application at 1 and 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081342Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested chickpea plants plots assessed as nematode population per cm3 soil measured 110 days post dose following field application at 2 kg of active ingredient/2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081357Drug level in Cicer arietinum (chickpea) green seeds measured 120 days post dose following field application at 1 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081374Toxicity in Rattus norvegicus (rat)2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081373Drug level in Cicer arietinum (chickpea) roots measured 15 days post dose following field application at 1 and 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081331Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested tomato plants plots assessed as nematode population per cm3 soil measured 55 days post dose following field application at 1 kg of active ingredient/hec2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081344Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested chickpea plants plots assessed as nematode population per cm3 soil measured 55 days post dose following field application at 2 kg of active ingredient/hectare (Rvb = 1.8 to2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081369Drug absorption in Solanum lycopersicum (tomato) roots assessed as mean drug level measured post dose following field application at 1 and 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081341Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested chickpea plants plots assessed as nematode population per cm3 soil measured 110 days post dose following field application at 1 kg of active ingredient/hectare (Rvb = 1.8 t2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081356Drug level in Cicer arietinum (chickpea) green seeds measured 90 days post dose following field application at 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081359Drug level in Cicer arietinum (chickpea) green seeds measured 90 days post dose following field application at 1 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081339Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested chickpea plants plots assessed as reduction in nematode population measured 55 days post dose following field application at 1 to 2 kg of active ingredi2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081351Drug level in Solanum lycopersicum (tomato) green seeds measured 120 days post dose following field application at 1 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081354Drug level in Cicer arietinum (chickpea) green seeds measured 120 days post dose following field application at 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081372Drug level in Solanum lycopersicum (tomato) roots measured 15 days post dose following field application at 1 and 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081336Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested tomato plants plots assessed as reduction in nematode population measured 110 days post dose following field application at 1 to 2 kg of active ingredie2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081326Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested tomato plants plots assessed as nematode population per cm3 soil measured 110 days post dose following field application at 2 kg of active ingredient/he2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081347Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested chickpea plants plots assessed as nematode population per cm3 soil measured 55 days post dose following field application at 1 kg of active ingredient/h2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081340Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested chickpea plants plots assessed as nematode population per cm3 soil measured 110 days post dose following field application at 2 kg of active ingredient/hectare (Rvb = 1.8 t2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081345Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested chickpea plants plots assessed as nematode population per cm3 soil measured 55 days post dose following field application at 1 kg of active ingredient/hectare (Rvb = 1.8 to2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081350Drug level in Solanum lycopersicum (tomato) green seeds measured 90 days post dose following field application at 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081333Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested in tomato plants plots assessed as reduction in nematode population measured 55 days post dose following field application at 1 to 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID977602Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID1081358Drug level in Cicer arietinum (chickpea) green seeds measured 100 days post dose following field application at 1 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081353Drug level in Solanum lycopersicum (tomato) green seeds measured 90 days post dose following field application at 1 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID399290Inhibition of acetylcholinesterase from nerve tissue of Lymnaea acuminata at 0.5 ug w/v relative to control
AID1081349Drug level in Solanum lycopersicum (tomato) green seeds measured 100 days post dose following field application at 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081329Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested tomato plants plots assessed as nematode population per cm3 soil measured 55 days post dose following field application at 1 kg of active ingredient/hectare (Rvb = 1.38 to 2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID399288In vivo inhibition of acetylcholinesterase from nerve tissue of Lymnaea acuminata at 30 mg/l relative to control
AID1081368Drug translocation in Solanum lycopersicum (tomato) roots assessed as mean drug level measured post dose following field application at 1 and 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081360Solubility in water2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081337Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested chickpea plants plots assessed as reduction in nematode population measured 110 days post dose following field application at 1 to 2 kg of active ingred2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081328Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested tomato plants plots assessed as nematode population per cm3 soil measured 55 days post dose following field application at 2 kg of active ingredient/hectare (Rvb = 1.38 to 2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081343Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested chickpea plants plots assessed as nematode population per cm3 soil measured 110 days post dose following field application at 1 kg of active ingredient/2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081324Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested tomato plants plots assessed as nematode population per cm3 soil measured 110 days post dose following field application at 2 kg of active ingredient/hectare (Rvb = 1.38 to2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081348Drug level in Solanum lycopersicum (tomato) green seeds measured 120 days post dose following field application at 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081332Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested tomato plants plots assessed as reduction in nematode population measured 110 days post dose following field application at 1 to 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081355Drug level in Cicer arietinum (chickpea) green seeds measured 100 days post dose following field application at 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081335Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested chickpea plants plots assessed as reduction in nematode population measured 55 days post dose following field application at 1 to 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081338Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested tomato plants plots assessed as reduction in nematode population measured 55 days post dose following field application at 1 to 2 kg of active ingredien2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081352Drug level in Solanum lycopersicum (tomato) green seeds measured 100 days post dose following field application at 1 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081346Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested chickpea plants plots assessed as nematode population per cm3 soil measured 55 days post dose following field application at 2 kg of active ingredient/h2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081330Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested tomato plants plots assessed as nematode population per cm3 soil measured 55 days post dose following field application at 2 kg of active ingredient/hec2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081327Nematicidal activity against root-knot nematode Meloidogyne incognita J2 (root-knot nematode) infested tomato plants plots assessed as nematode population per cm3 soil measured 110 days post dose following field application at 1 kg of active ingredient/he2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID1081334Nematicidal activity against Rotylenchulus reniformis (reniform nematode) infested chickpea plants plots assessed as reduction in nematode population measured 110 days post dose following field application at 1 to 2 kg of active ingredient/hectare2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
AID977599Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID1159550Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening2015Nature cell biology, Nov, Volume: 17, Issue:11
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (116)

TimeframeStudies, This Drug (%)All Drugs %
pre-199039 (33.62)18.7374
1990's11 (9.48)18.2507
2000's24 (20.69)29.6817
2010's35 (30.17)24.3611
2020's7 (6.03)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (0.75%)5.53%
Reviews2 (1.50%)6.00%
Case Studies6 (4.51%)4.05%
Observational0 (0.00%)0.25%
Other124 (93.23%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
niclosamide[no description available]medium10benzamides;
C-nitro compound;
monochlorobenzenes;
salicylanilides;
secondary carboxamide		anthelminthic drug;
anticoronaviral agent;
antiparasitic agent;
apoptosis inducer;
molluscicide;
piscicide;
STAT3 inhibitor
physostigmine[no description available]high20carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic
carbaryl[no description available]high70carbamate ester;
naphthalenes		acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
plant growth retardant
mexacarbate[no description available]medium20benzenes
formothion[no description available]medium10dicarboximide
carbofuran[no description available]high1401-benzofurans;
carbamate ester		acaricide;
agrochemical;
avicide;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nematicide
fenamiphos[no description available]medium30organophosphate insecticide;
organophosphate nematicide;
phosphoramidate ester		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
triazophos[no description available]high10organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide
dibutylaminosulfenylcarbofuran[no description available]medium101-benzofurans;
carbamate ester		acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide
cadusafos[no description available]high10organic thiophosphate;
organothiophosphate insecticide		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide
diamide[no description available]medium101,1'-azobis(N,N-dimethylformamide)
clothianidin[no description available]medium101,3-thiazoles;
2-nitroguanidine derivative;
clothianidin;
organochlorine compound		environmental contaminant;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic
didodecyldimethylammonium[no description available]medium10
ethion[no description available]high30organic thiophosphateacaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide
dimethoate[no description available]high100monocarboxylic acid amide;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
silver[no description available]medium20copper group element atom;
elemental silver		Escherichia coli metabolite
terbufos[no description available]high80organic thiophosphate;
organosulfur compound;
organothiophosphate insecticide		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide
atropine[no description available]medium21
glutamine[no description available]medium11amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
chlorpyrifos[no description available]high30chloropyridine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
obidoxime chloride[no description available]medium10
imidacloprid[no description available]medium10imidacloprid;
imidazolidines;
monochloropyridine		environmental contaminant;
genotoxin;
neonicotinoid insectide;
nicotinic acetylcholine receptor agonist;
xenobiotic
dextrothyroxine[no description available]medium10
avermectin[no description available]medium10
fenthion[no description available]high40organic thiophosphateacaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide
ethoprophos[no description available]high30organic thiophosphate;
organothiophosphate insecticide		agrochemical;
antinematodal drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
malathion[no description available]medium60diester;
ethyl ester;
organic thiophosphate
disulfoton[no description available]high110organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
gold[no description available]medium10copper group element atom;
elemental gold
clay[no description available]medium20
methyl salicylate[no description available]medium10benzoate ester;
methyl ester;
salicylates		flavouring agent;
insect attractant;
metabolite
diethyl malonate[no description available]medium10dicarboxylic acid
parathion[no description available]high120C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
mouse metabolite
potassium cyanide[no description available]medium10cyanide salt;
one-carbon compound;
potassium salt		EC 1.15.1.1 (superoxide dismutase) inhibitor;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
neurotoxin
salicylates[no description available]medium10monohydroxybenzoateplant metabolite
glycine[no description available]medium10alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
2,4-dichlorophenoxyacetic acid[no description available]medium20chlorophenoxyacetic acid;
dichlorobenzene		agrochemical;
defoliant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
environmental contaminant;
phenoxy herbicide;
synthetic auxin
phoxim[no description available]medium10
1-octyl-3-methylimidazolium hexafluorophosphate[no description available]medium10
triazoles[no description available]medium201,2,3-triazole
carbamates[no description available]medium60amino-acid anion
copper gluconate[no description available]medium10organic molecular entity
methyl parathion[no description available]high50C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
genotoxin
beta-glucono-1,5-lactone[no description available]medium10aldono-1,5-lactone;
gluconolactone		animal metabolite;
mouse metabolite
permethrin[no description available]medium10cyclopropanecarboxylate ester;
cyclopropanes		agrochemical;
ectoparasiticide;
pyrethroid ester acaricide;
pyrethroid ester insecticide;
scabicide
fonofos[no description available]high40organic thiophosphate;
organothiophosphate insecticide		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
coumaphos[no description available]high10organic thiophosphate;
organochlorine compound;
organothiophosphate insecticide		acaricide;
agrochemical;
antinematodal drug;
avicide;
EC 3.1.1.8 (cholinesterase) inhibitor
tryptophan[no description available]medium10erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
bensulide[no description available]medium10benzenes
methidathion[no description available]high10organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
methamidophos[no description available]high10organic thiophosphate;
organothiophosphate insecticide;
phosphoramide		acaricide;
agrochemical;
avicide
chlorfenvinphos[no description available]medium20dichlorobenzene;
organic phosphate;
organochlorine acaricide;
organochlorine insecticide;
organophosphate insecticide		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
quinalphos[no description available]high10organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
chlorophyll a[no description available]medium10chlorophyll;
methyl ester		cofactor
trichlorfon[no description available]medium20organic phosphonate;
organochlorine compound;
phosphonic ester		agrochemical;
anthelminthic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide
kynurenic acid[no description available]medium10monohydroxyquinoline;
quinolinemonocarboxylic acid		G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite
citric acid, anhydrous[no description available]medium10tricarboxylic acidantimicrobial agent;
chelator;
food acidity regulator;
fundamental metabolite
bilirubin[no description available]medium10biladienes;
dicarboxylic acid		antioxidant;
human metabolite;
mouse metabolite
uric acid[no description available]medium10uric acidEscherichia coli metabolite;
human metabolite;
mouse metabolite
7-methylguanine[no description available]medium107-methylguanine
xanthurenic acid[no description available]medium10dihydroxyquinoline;
quinolinemonocarboxylic acid		animal metabolite;
iron chelator;
metabotropic glutamate receptor agonist;
vesicular glutamate transport inhibitor
guanine[no description available]medium102-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
suberic acid[no description available]medium10alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
cholic acid[no description available]medium1012alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
bile acid;
C24-steroid;
trihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
indican[no description available]medium10beta-D-glucoside;
exopolysaccharide;
indolyl carbohydrate
thiophosphoric acid[no description available]medium10phosphorothioic acid
caprylates[no description available]medium10fatty acid anion 8:0;
straight-chain saturated fatty acid anion		human metabolite;
Saccharomyces cerevisiae metabolite
ozone[no description available]medium20elemental molecule;
gas molecular entity;
reactive oxygen species;
triatomic oxygen		antiseptic drug;
disinfectant;
electrophilic reagent;
greenhouse gas;
mutagen;
oxidising agent;
tracer
indoleacetic acid[no description available]medium10indole-3-acetic acids;
monocarboxylic acid		auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite
dichlorvos[no description available]medium20alkenyl phosphate;
dialkyl phosphate;
organochlorine acaricide;
organophosphate insecticide		anthelminthic drug;
antibacterial agent;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
fenitrothion[no description available]high30C-nitro compound;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide
trichloronate[no description available]medium10organochlorine compound
tetrachlorvinphos[no description available]medium10alkenyl phosphate;
dialkyl phosphate;
organochlorine insecticide;
organophosphate insecticide;
trichlorobenzene		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
phosphamidon[no description available]medium30
tebuconazole[no description available]medium10monochlorobenzenes;
tertiary alcohol;
triazoles
sulfur[no description available]medium10chalcogen;
nonmetal atom		macronutrient
acephate[no description available]high10mixed diacylamine;
organic thiophosphate;
organothiophosphate insecticide;
phosphoramide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
aldicarb[no description available]medium70
sulfotepp[no description available]high10organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
pyrethrins[no description available]medium40
fenvalerate[no description available]medium20aromatic ether;
carboxylic ester;
monochlorobenzenes		pyrethroid ester acaricide;
pyrethroid ester insecticide
dieldrin[no description available]medium40epoxide;
organochlorine compound;
organochlorine insecticide		carcinogenic agent;
xenobiotic
aldrin[no description available]medium30
cypermethrin[no description available]medium10aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound		agrochemical;
molluscicide;
pyrethroid ester acaricide;
pyrethroid ester insecticide
metribuzin[no description available]medium101,2,4-triazines;
cyclic ketone;
organic sulfide		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
monocrotophos[no description available]medium30alkenyl phosphate;
dialkyl phosphate;
monocarboxylic acid amide;
organophosphate insecticide		acaricide;
agrochemical;
avicide;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
thiourea[no description available]medium10one-carbon compound;
thioureas;
ureas		antioxidant;
chromophore
cyanamide[no description available]medium10nitrile;
one-carbon compound		EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
phosphorus[no description available]medium10monoatomic phosphorus;
nonmetal atom;
pnictogen		macronutrient
propanil[no description available]medium10anilide;
dichlorobenzene		herbicide
diazinon[no description available]high30organic thiophosphate;
pyrimidines		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
nematicide;
xenobiotic
heptachlor[no description available]medium20cyclodiene organochlorine insecticideagrochemical;
antibacterial agent;
antifungal agent;
GABA-gated chloride channel antagonist;
persistent organic pollutant
linuron[no description available]medium10dichlorobenzene;
phenylureas		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
paraoxon[no description available]medium20aryl dialkyl phosphate;
organophosphate insecticide		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
mouse metabolite
dichlorodiphenyldichloroethane[no description available]medium10chlorophenylethane;
monochlorobenzenes;
organochlorine insecticide		xenobiotic metabolite
ddt[no description available]medium30benzenoid aromatic compound;
chlorophenylethane;
monochlorobenzenes;
organochlorine insecticide		bridged diphenyl acaricide;
carcinogenic agent;
endocrine disruptor;
persistent organic pollutant
trifluralin[no description available]medium10(trifluoromethyl)benzenes;
C-nitro compound;
substituted aniline		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
dichlorodiphenyl dichloroethylene[no description available]medium20chlorophenylethylene;
monochlorobenzenes		human xenobiotic metabolite;
persistent organic pollutant
mevinphos[no description available]medium10
chlordan[no description available]medium10cyclodiene organochlorine insecticideGABA-gated chloride channel antagonist;
persistent organic pollutant
acetonitrile[no description available]medium10aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
methanol[no description available]medium10alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
phosalone[no description available]high101,3-benzoxazoles;
carbamate ester;
organochlorine insecticide;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
flavin-adenine dinucleotide[no description available]medium10flavin adenine dinucleotide;
vitamin B2		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prosthetic group
paraquat[no description available]medium10organic cationgeroprotector;
herbicide
alachlor[no description available]medium10aromatic amide;
monocarboxylic acid amide;
organochlorine compound		environmental contaminant;
herbicide;
xenobiotic
3-hydroxycarbofuran[no description available]medium101-benzofurans
thiometon[no description available]high10organic thiophosphate;
organosulfur compound;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
methylnitronitrosoguanidine[no description available]medium10nitroso compoundalkylating agent
atrazine[no description available]medium10chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
simazine[no description available]medium10chloro-1,3,5-triazine;
diamino-1,3,5-triazine		environmental contaminant;
herbicide;
xenobiotic
iodine[no description available]medium10diatomic iodinenutrient
endrin[no description available]medium10
azinphosmethyl[no description available]high10benzotriazines;
organic thiophosphate;
organothiophosphate insecticide		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
iodine[no description available]medium10halide anion;
monoatomic iodine		human metabolite
sucrose[no description available]medium10glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
glyphosate[no description available]medium10glycine derivative;
phosphonic acid		agrochemical;
EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor;
herbicide
fusarium[no description available]medium10
tacrine[no description available]low00acridines;
aromatic amine		EC 3.1.1.7 (acetylcholinesterase) inhibitor
bendiocarb[no description available]low00benzodioxoles;
carbamate ester		agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
berberine[no description available]low00alkaloid antibiotic;
berberine alkaloid;
botanical anti-fungal agent;
organic heteropentacyclic compound		antilipemic drug;
antineoplastic agent;
antioxidant;
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor;
EC 1.21.3.3 (reticuline oxidase) inhibitor;
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
hypoglycemic agent;
metabolite;
potassium channel blocker
donepezil[no description available]low00aromatic ether;
indanones;
piperidines;
racemate		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nootropic agent
methomyl[no description available]low00aliphatic sulfide;
carbamate ester		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
nematicide;
xenobiotic
naled[no description available]low00dialkyl phosphate;
organobromine compound;
organochlorine compound;
organophosphate insecticide		acaricide;
agrochemical;
antibacterial agent;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
neostigmine[no description available]low00quaternary ammonium ionantidote to curare poisoning;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
propoxur[no description available]low00aromatic ether;
carbamate ester		acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
temefos[no description available]medium00organic sulfide;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
ectoparasiticide
terbutaline[no description available]low00phenylethanolamines;
resorcinols		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
hypoglycemic agent;
sympathomimetic agent;
tocolytic agent
famophos[no description available]medium00organic thiophosphate;
organothiophosphate insecticide		agrochemical;
anthelminthic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
fensulfothion[no description available]medium00organic thiophosphate;
organothiophosphate insecticide;
sulfoxide		agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide
pyridafenthion[no description available]medium00organic thiophosphate;
organothiophosphate insecticide;
pyridazinone		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
galantamine[no description available]low00benzazepine alkaloid fundamental parent;
benzazepine alkaloid;
organic heterotetracyclic compound;
tertiary amino compound		antidote to curare poisoning;
cholinergic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
plant metabolite
liriodenine[no description available]low00alkaloid antibiotic;
cyclic ketone;
organic heteropentacyclic compound;
oxacycle;
oxoaporphine alkaloid		antifungal agent;
antimicrobial agent;
antineoplastic agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
metabolite
imperatorin[no description available]low00psoralensEC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite
phosmet[no description available]medium00organic thiophosphate;
organothiophosphate insecticide;
phthalimides		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
demeton-s-methyl[no description available]medium00organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
dimethoxon[no description available]medium00organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
metolcarb[no description available]low00carbamate esteracaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
aminocarb[no description available]low00carbamate ester;
toluenes		acaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
molluscicide
methiocarb[no description available]low00aryl sulfide;
carbamate ester;
methyl sulfide		acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
molluscicide;
xenobiotic
phenylphosphonothioic acid, 2-ethyl 2-(4-nitrophenyl) ester[no description available]medium00organic phosphonate;
organothiophosphate insecticide;
phosphonic ester		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
mecarbam[no description available]medium00carbamate ester;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
phenthoate, (+-)-isomer[no description available]medium00ethyl ester;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
isoprocarb[no description available]low00carbamate esteragrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
cyanophos[no description available]medium00organic thiophosphate;
organothiophosphate insecticide		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
azinphos ethyl[no description available]medium00organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
bpmc[no description available]low00carbamate esteragrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
herbicide;
insecticide
chlorpyrifos-methyl[no description available]medium00chloropyridine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
hypochlorous acid[no description available]low00chlorine oxoacid;
reactive oxygen species		EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite
edifenphos[no description available]medium00organic thiophosphateantifungal agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
neurotoxin;
phospholipid biosynthesis inhibitor
formetanate[no description available]low00carbamate esteracaricide;
agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
pirimicarb[no description available]low00aminopyrimidine;
carbamate ester;
tertiary amino compound		agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
isofenphos[no description available]medium00isopropyl ester;
organic phosphonate;
organothiophosphate insecticide;
phosphonic ester;
salicylates		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
pirimiphos methyl[no description available]medium00aminopyrimidine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
environmental contaminant;
insecticide
croneton[no description available]low00carbamate esteragrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
prothiophos[no description available]medium00dichlorobenzene;
organic thiophosphate;
organosulfur compound		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide
sulprofos[no description available]medium00organic thiophosphate;
organosulfur compound;
organothiophosphate insecticide		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
profenofos[no description available]medium00monochlorobenzenes;
organic thiophosphate;
organochlorine insecticide;
organophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
vx[no description available]medium00organic thiophosphate;
tertiary amino compound		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
neurotoxin
deltanit[no description available]low001-benzofurans;
carbamate ester		agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
bambuterol hydrochloride[no description available]low00carbamate ester;
hydrochloride;
phenylethanolamines		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
prodrug;
sympathomimetic agent
bambuterol[no description available]low00carbamate ester;
phenylethanolamines		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
prodrug;
sympathomimetic agent;
tocolytic agent
benfuracarb[no description available]low001-benzofurans;
carbamate ester;
ethyl ester		agrochemical;
carbamate insecticide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
heptenophos[no description available]low00organochlorine compound;
organophosphate insecticide;
trialkyl phosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
isoimperatorin[no description available]low00psoralensEC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite
azamethiphos[no description available]medium00organic thiophosphate;
organochlorine acaricide;
organochlorine insecticide;
organothiophosphate insecticide		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
loganin[no description available]low00beta-D-glucoside;
cyclopentapyran;
enoate ester;
iridoid monoterpenoid;
methyl ester;
monosaccharide derivative;
secondary alcohol		anti-inflammatory agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
EC 3.4.23.46 (memapsin 2) inhibitor;
neuroprotective agent;
plant metabolite
bay 93820[no description available]medium00isopropyl ester;
organic phosphonate;
organothiophosphate insecticide;
phosphonic ester;
salicylates		agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
fosthiazate[no description available]medium00organic phosphonate;
organothiophosphate insecticide;
phosphonic ester		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide
pyraclofos[no description available]medium00monochlorobenzenes;
organic thiophosphate;
organochlorine insecticide;
organosulfur compound;
organothiophosphate insecticide;
pyrazoles		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
ar-turmerone[no description available]low00enone;
sesquiterpenoid		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
plant metabolite
corynoline[no description available]low00benzophenanthridine alkaloid;
cyclic acetal;
isoquinolines;
organic heterohexacyclic compound;
secondary alcohol		antineoplastic agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
hepatoprotective agent;
metabolite
decursinol[no description available]low00cyclic ether;
delta-lactone;
organic heterotricyclic compound;
secondary alcohol		analgesic;
antineoplastic agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite
huperzine a[no description available]low00organic heterotricyclic compound;
primary amino compound;
pyridone;
sesquiterpene alkaloid		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
neuroprotective agent;
nootropic agent;
plant metabolite
cyclanoline[no description available]low00berberine alkaloid;
quaternary ammonium ion		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
plant metabolite
geissospermine[no description available]low00indole alkaloid;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound		EC 3.1.1.7 (acetylcholinesterase) inhibitor
bellidifolin[no description available]low00polyphenol;
xanthones		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
hypoglycemic agent;
metabolite
demethylbellidifolin[no description available]low00tetrol;
xanthones		antioxidant;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite;
mutagen;
radical scavenger
norswertianolin[no description available]low00beta-D-glucoside;
xanthones		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite
erucyl amide[no description available]low0013-docosenamideEC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite;
mammalian metabolite;
plant metabolite;
rat metabolite
dicrotophos[no description available]low00dialkyl phosphate;
organophosphate insecticide		acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
propetamphos[no description available]low00isopropyl ester;
organophosphate insecticide;
phosphoramidate ester		agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
bis(7)-tacrine[no description available]low00secondary amino compoundapoptosis inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
neuroprotective agent
arisugacin[no description available]low00aromatic ether;
delta-lactone;
enone;
organic heterotetracyclic compound;
tertiary alcohol		antimicrobial agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite;
Penicillium metabolite
11-hydroxysugiol[no description available]low00abietane diterpenoid;
carbotricyclic compound;
catechols;
cyclic terpene ketone;
meroterpenoid		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
plant metabolite
xyloketal a[no description available]low00organic heteroheptacyclic compound;
xyloketal		EC 3.1.1.7 (acetylcholinesterase) inhibitor
lycojapodine a[no description available]low00alkaloid;
bridged compound;
cyclic ketone;
lactone;
organic heterotetracyclic compound		anti-HIV-1 agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite
ambenonium[no description available]low00quaternary ammonium ionEC 3.1.1.8 (cholinesterase) inhibitor
distigmine[no description available]low00carbamate ester;
pyridinium ion		EC 3.1.1.8 (cholinesterase) inhibitor;
muscarinic agonist
disulfiram[no description available]low00organic disulfide;
organosulfur acaricide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor
edrophonium[no description available]low00phenols;
quaternary ammonium ion		antidote;
diagnostic agent;
EC 3.1.1.8 (cholinesterase) inhibitor
tyramine[no description available]low00monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
neostigmine methylsulfate[no description available]low00arylammonium sulfate saltEC 3.1.1.8 (cholinesterase) inhibitor
methylene blue[no description available]low00organic chloride saltacid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer
ambenonium chloride[no description available]low00organic chloride salt;
quaternary ammonium salt		EC 3.1.1.8 (cholinesterase) inhibitor;
neurotransmitter agent
edrophonium chloride[no description available]low00chloride salt;
quaternary ammonium salt		antidote;
diagnostic agent;
EC 3.1.1.8 (cholinesterase) inhibitor
echothiophate iodide[no description available]low00iodide salt;
quaternary ammonium salt		antiglaucoma drug;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic
bupivacaine hydrochloride[no description available]low00hydrochloride;
racemate		adrenergic antagonist;
amphiphile;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor;
local anaesthetic
rivastigmine[no description available]low00carbamate ester;
tertiary amino compound		cholinergic drug;
EC 3.1.1.8 (cholinesterase) inhibitor;
neuroprotective agent
levobupivacaine[no description available]low001-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamideadrenergic antagonist;
amphiphile;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor;
local anaesthetic
levobupivacaine hydrochloride[no description available]low001-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochlorideadrenergic antagonist;
amphiphile;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor;
local anaesthetic
nostocarboline[no description available]low00alkaloid;
beta-carbolines;
organic cation;
organochlorine compound		antimalarial;
EC 3.1.1.8 (cholinesterase) inhibitor;
metabolite
alternariol[no description available]low00benzochromenone;
phenols		EC 3.1.1.8 (cholinesterase) inhibitor;
metabolite;
mycotoxin
lucidenic acid n[no description available]low00cyclic terpene ketone;
dioxo monocarboxylic acid;
secondary alcohol;
tetracyclic triterpenoid		antineoplastic agent;
EC 3.1.1.8 (cholinesterase) inhibitor;
metabolite
benzyl benzoate[no description available]low00benzoate ester;
benzyl ester		acaricide;
plant metabolite;
scabicide
endosulfan[no description available]low00cyclic sulfite ester;
cyclodiene organochlorine insecticide		acaricide;
agrochemical;
GABA-gated chloride channel antagonist;
persistent organic pollutant
hexachlorophene[no description available]low00bridged diphenyl fungicide;
polyphenol;
trichlorobenzene		acaricide;
antibacterial agent;
antifungal agrochemical;
antiseptic drug
naphthazarin[no description available]low00hydroxy-1,4-naphthoquinoneacaricide;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
geroprotector;
plant metabolite
2-methyl-5-(1-methylethenyl)cyclohexanol[no description available]low00p-menthane monoterpenoid;
secondary alcohol		acaricide;
plant metabolite;
volatile oil component
dichlofluanid[no description available]low00organochlorine compound;
organofluorine compound;
phenylsulfamide fungicide;
sulfamides		acaricide;
antifungal agrochemical
usnic acid[no description available]low00dibenzofurans;
methyl ketone;
polyphenol		acaricide;
antifungal agent;
lichen metabolite
benomyl[no description available]low00aromatic amide;
benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		acaricide;
anthelminthic drug;
antifungal agrochemical;
microtubule-destabilising agent;
tubulin modulator
amitraz[no description available]low00formamidines;
tertiary amino compound		acaricide;
environmental contaminant;
insecticide;
xenobiotic
fluazuron[no description available]low00aromatic ether;
chloropyridine;
monochlorobenzenes;
N-acylurea;
organochlorine acaricide;
organofluorine acaricide;
phenylureas		acaricide;
mite growth regulator
sulfluramid[no description available]low00sulfonamideacaricide;
environmental contaminant;
insecticide;
xenobiotic
fenazaquin[no description available]low00quinazolinesacaricide;
mitochondrial NADH:ubiquinone reductase inhibitor
acequinocyl[no description available]low001,4-naphthoquinones;
acetate ester		acaricide;
mitochondrial cytochrome-bc1 complex inhibitor
bifenazate[no description available]low00carboxylic esteracaricide
4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1h-pyrrole-3-carbonitrile[no description available]low00monochlorobenzenes;
nitrile;
organobromine compound;
organochlorine acaricide;
organochlorine insecticide;
organofluorine acaricide;
organofluorine insecticide;
pyrroles		acaricide;
antifouling biocide;
insecticide
ethyl oleate[no description available]low00long-chain fatty acid ethyl esteracaricide;
plant metabolite
4-(2,4-dichlorophenoxy)butyric acid[no description available]low00aromatic ether;
monocarboxylic acid;
organochlorine compound		agrochemical;
phenoxy herbicide;
synthetic auxin
benefin[no description available]low00C-nitro compound;
organofluorine compound;
substituted aniline;
tertiary amino compound		agrochemical;
herbicide
dicamba[no description available]low00dichlorobenzene;
methoxybenzoic acid		agrochemical;
environmental contaminant;
herbicide;
synthetic auxin;
xenobiotic
dichlobanil[no description available]low00dichlorobenzene;
nitrile		agrochemical;
cellulose synthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
resmethrin[no description available]low00cyclopropanecarboxylate ester;
furans		agrochemical;
pyrethroid ester insecticide
roxarsone[no description available]low002-nitrophenols;
organoarsonic acid		agrochemical;
animal growth promotant;
antibacterial drug;
coccidiostat
dinitrofluorobenzene[no description available]low00C-nitro compound;
organofluorine compound		agrochemical;
allergen;
chromatographic reagent;
EC 2.7.3.2 (creatine kinase) inhibitor;
protein-sequencing agent;
spectrophotometric reagent
fenuron[no description available]low003-(3,4-substituted-phenyl)-1,1-dimethylureaagrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
xenobiotic
glyoxal[no description available]low00dialdehydeagrochemical;
allergen;
pesticide;
plant growth regulator
bicuculline[no description available]low00benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
carvacrol[no description available]low00botanical anti-fungal agent;
p-menthane monoterpenoid;
phenols		agrochemical;
antimicrobial agent;
flavouring agent;
TRPA1 channel agonist;
volatile oil component
nitrapyrin[no description available]low00chloropyridineagrochemical;
antibacterial agent;
nitrification inhibitor
lenacil[no description available]low00cyclopentapyrimidineagrochemical;
environmental contaminant;
herbicide;
xenobiotic
fluometuron[no description available]low00(trifluoromethyl)benzenes;
3-(3,4-substituted-phenyl)-1,1-dimethylurea		agrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
xenobiotic
molinate[no description available]low00azepanes;
monothiocarbamic ester		agrochemical;
antispermatogenic agent;
herbicide
quinomethionate[no description available]low00dithioloquinoxaline;
quinoxaline acaricide;
quinoxaline antifungal agent		agrochemical
mepiquat[no description available]low00quaternary ammonium ionagrochemical;
Maillard reaction product;
plant growth retardant
asulam[no description available]low00carbamate ester;
primary amino compound;
substituted aniline;
sulfonamide		agrochemical;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic
desmedipham[no description available]low00carbamate esteragrochemical;
environmental contaminant;
herbicide;
xenobiotic
chlortoluron[no description available]low00monochlorobenzenes;
phenylureas		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
oryzalin[no description available]low00aromatic amine;
C-nitro compound;
sulfonamide;
tertiary amino compound		agrochemical;
antimitotic;
herbicide
methoxuron[no description available]low003-(3,4-substituted-phenyl)-1,1-dimethylurea;
monochlorobenzenes;
monomethoxybenzene		agrochemical;
environmental contaminant;
herbicide;
photosystem-II inhibitor;
plant growth regulator;
xenobiotic
pronamide[no description available]low00benzamides;
dichlorobenzene;
terminal acetylenic compound		agrochemical;
herbicide
2,6-diisopropylnaphthalene[no description available]low00naphthalenesagrochemical;
plant growth retardant
norflurazone[no description available]low00(trifluoromethyl)benzenes;
organochlorine compound;
pyridazinone;
secondary amino compound		agrochemical;
carotenoid biosynthesis inhibitor;
herbicide
isoproturon[no description available]low003-(3,4-substituted-phenyl)-1,1-dimethylureaagrochemical;
environmental contaminant;
herbicide;
xenobiotic
cyphenothrin[no description available]low00cyclopropanecarboxylate esteragrochemical;
pyrethroid ester insecticide
pendimethalin[no description available]low00C-nitro compound;
secondary amino compound;
substituted aniline		agrochemical;
environmental contaminant;
herbicide
decamethrin[no description available]low00aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organobromine compound		agrochemical;
antifeedant;
calcium channel agonist;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
pyrethroid ester insecticide
triclopyr[no description available]low00aromatic ether;
chloropyridine;
monocarboxylic acid		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
acifluorfen[no description available]low00aromatic ether;
benzoic acids;
C-nitro compound;
monocarboxylic acid;
organochlorine compound;
organofluorine compound		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
fenpropathrin, (+-)-isomer[no description available]low00aromatic ether;
cyclopropanecarboxylate ester		agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide
chlorsulfuron[no description available]low00methoxy-1,3,5-triazine;
monochlorobenzenes;
N-sulfonylurea		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide
fluvalinate[no description available]low00(trifluoromethyl)benzenes;
aromatic ether;
monochlorobenzenes;
nitrile;
organochlorine acaricide;
organochlorine insecticide;
organofluorine acaricide;
organofluorine insecticide		agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide
fomesafen[no description available]low00aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
oxadixyl[no description available]low00anilide fungicide;
aromatic amide;
carbohydrazide;
ether;
oxazolidinone		agrochemical
clomazone[no description available]low00isoxazolidinone;
monochlorobenzenes		agrochemical;
carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
methyl bensulfuron[no description available]low00aromatic ether;
methyl ester;
N-sulfonylurea;
pyrimidines		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide
chlorimuron ethyl[no description available]low00aromatic ether;
ethyl ester;
N-sulfonylurea;
organochlorine pesticide;
pyrimidines;
sulfamoylbenzoate		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide
cuprous chloride[no description available]low00copper molecular entity;
inorganic chloride		agrochemical;
molluscicide
nitarsone[no description available]low00C-nitro compound;
organoarsonic acid		agrochemical;
antiprotozoal drug
triasulfuron[no description available]low001,3,5-triazines;
aromatic ether;
N-sulfonylurea;
organochlorine compound		agrochemical;
herbicide
thifensulfuron methyl[no description available]low001,3,5-triazines;
methyl ester;
N-sulfonylurea;
thiophenes		agrochemical;
environmental contaminant;
herbicide;
xenobiotic
isoxaflutole[no description available]low00(trifluoromethyl)benzenes;
aromatic ketone;
cyclopropanes;
isoxazoles;
sulfone		agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
proherbicide
n-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl)phenyl)methanesulfonamide[no description available]low00dichlorobenzene;
organofluorine compound;
sulfonamide;
triazoles		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
cloransulam-methyl[no description available]low00methyl ester;
monochlorobenzenes;
organofluorine compound;
sulfonamide;
triazolopyrimidines		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
herbicide
raiser[no description available]low00(trifluoromethyl)benzenes;
organochlorine compound;
pyrrolidines		agrochemical;
carotenoid biosynthesis inhibitor;
herbicide
quinclorac[no description available]low00monocarboxylic acid;
organochlorine compound;
quinolinemonocarboxylic acid		agrochemical;
herbicide;
synthetic auxin
aclonifen[no description available]low00aromatic ether;
C-nitro compound;
monochlorobenzenes;
primary amino compound;
substituted aniline		agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
s 53482[no description available]low00benzoxazine;
dicarboximide;
organofluorine compound;
terminal acetylenic compound		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide;
teratogenic agent
clodinafop-propargyl[no description available]low00aromatic ether;
carboxylic ester;
organochlorine compound;
organofluorine compound;
propyzamide;
pyridines		agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
herbicide
triflusulfuron-methyl[no description available]low001,3,5-triazines;
aromatic ether;
benzoate ester;
methyl ester;
N-sulfonylurea;
organofluorine compound;
tertiary amino compound		agrochemical;
EC 2.2.1.6 (acetolactate synthase) inhibitor;
proherbicide
cyfluthrin[no description available]low00aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound		agrochemical;
pyrethroid ester insecticide
1-methylcyclopropene[no description available]low00cycloalkene;
cyclopropenes		agrochemical;
plant growth regulator
cafenstrole[no description available]low00benzenes;
sulfone;
triazoles		agrochemical;
antimitotic;
herbicide
pinoxaden[no description available]low00pivalate ester;
pyrazolooxadiazepine		agrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
environmental contaminant;
proherbicide;
xenobiotic
tioxazafen[no description available]low001,2,4-oxadiazole;
thiophenes		agrochemical;
nematicide
cyhalothrin[no description available]low00aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound;
organofluorine compound		agrochemical;
pyrethroid ester acaricide;
pyrethroid ester insecticide
tolfenpyrad[no description available]low00aromatic amide;
aromatic ether;
organochlorine compound;
pyrazole insecticide		agrochemical;
antifungal agent;
EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor;
mitochondrial NADH:ubiquinone reductase inhibitor
pydrin, (s-(r*,r*))-isomer[no description available]low00fenvalerateagrochemical;
pyrethroid ester insecticide
mefenoxam[no description available]low00acylamino acid fungicide;
anilide fungicide;
D-alanine derivative;
methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate		agrochemical
fluensulfone[no description available]low001,3-thiazoles;
olefinic compound;
organochlorine pesticide;
organofluorine pesticide;
sulfone		agrochemical;
nematicide
tembotrione[no description available]low00aromatic ketone;
beta-triketone;
cyclic ketone;
ether;
monochlorobenzenes;
organofluorine compound;
sulfone		agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide
haloxyfop-P-methyl[no description available]low00methyl 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoateagrochemical;
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor;
proherbicide
alpha(-(cyclopropylcarbonyl)-2-(methyvlsulfonyl)-beta-oxo-4-(trifluromethyl)benzenepropanenitrile)[no description available]low00(trifluoromethyl)benzenes;
aromatic ketone;
beta-diketone;
cyclopropanes;
nitrile;
sulfone		agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide
cyenopyrafen[no description available]low00nitrile;
pivalate ester;
pyrazoles		agrochemical;
proacaricide
fluazaindolizine[no description available]low00aromatic amide;
imidazopyridine;
monocarboxylic acid amide;
monochlorobenzenes;
monomethoxybenzene;
N-sulfonylcarboxamide;
organofluorine pesticide		agrochemical;
nematicide
afidopyropen[no description available]low00cyclopropanecarboxylate ester;
organic heterotetracyclic compound;
pyridines;
secondary alcohol		agrochemical;
insecticide;
TRPV channel modulator
o,o-diethyl phosphorothionate[no description available]low00organic thiophosphatehuman xenobiotic metabolite;
mouse metabolite
amifostine anhydrous[no description available]low00diamine;
organic thiophosphate		antioxidant;
prodrug;
radiation protective agent
butyl phosphorotrithioate[no description available]low00organic thiophosphatedefoliant
dichlofenthion[no description available]low00organic thiophosphate
o,o-diethyl dithiophosphate[no description available]low00organic thiophosphate
ronnel[no description available]low00organic thiophosphate
malaoxon[no description available]low00diester;
ethyl ester;
organic thiophosphate
bromophos[no description available]low00organic thiophosphate
salithion[no description available]low00organic thiophosphate
pyrazophos[no description available]low00ethyl ester;
organic thiophosphate;
pyrazolopyrimidine		antifungal agrochemical;
insecticide;
phospholipid biosynthesis inhibitor;
profungicide
iodofenphos[no description available]low00organic thiophosphate
o,o-diisopropyl-s-benzylthiophosphate[no description available]low00organic thiophosphateantifungal agrochemical;
phospholipid biosynthesis inhibitor
isazophos[no description available]low00organic thiophosphate
tolclofos-methyl[no description available]low00dichlorobenzene;
organic thiophosphate		antifungal agrochemical
tert-butylbicyclophosphorothionate[no description available]low00organic thiophosphate
s-phosphocysteine[no description available]low00organic thiophosphate;
phosphoamino acid;
S-substituted L-cysteine
o,o-dimethyl phosphorothionate[no description available]low00organic thiophosphate
ConditionIndicatedRelationship StrengthStudiesTrials
A-V Dissociation0low10
Abnormalities, Autosome0low20
Abnormalities, Chromosomal0low20
Abnormalities, Chromosome0low20
Abnormalities, Drug-Induced0low10
Acute Disease0low10
Agricultural Worker Disease0low10
Agricultural Worker's Disease0low10
Agricultural Workers' Diseases0low10
Alcohol Drinking0low10
Alcoholic Intoxication0low10
Anemia, Fanconi0low10
Atrioventricular Dissociation0low10
Atrioventricular Nodal Re-Entrant Tachycardia0low10
Atrioventricular Reentrant Tachycardia0low10
Atrophy0low10
Auriculo-Ventricular Dissociation0low10
Autosome Abnormalities0low20
Benign Neoplasms0low10
Body Weight0low10
Bovine Diseases0low20
Brain Dead0low10
Brain Death0low10
Brain Inflammation0low10
Cancer0low10
Cancer of Prostate0low20
Cancer of the Prostate0low20
Cat Diseases0low10
Cattle Diseases0low20
Child Development Deviations0low10
Child Development Disorders0low10
Child Development Disorders, Specific0low10
Chromosomal Aberrations0low20
Chromosome Aberrations0low20
Chromosome Abnormalities0low20
Chromosome-Defective Micronuclei0low10
Coma0low20
Coma Depasse0low10
Comatose0low20
Cytogenetic Aberrations0low20
Cytogenetic Abnormalities0low20
Day Blindness0low10
Delayed Effects, Prenatal Exposure0low10
Development Disorders, Child0low10
Developmental Delay Disorders0low10
Developmental Disabilities0low10
Disabilities, Developmental0low10
Diseases, Occupational0low10
Distorted Hearing0low10
Drug-Induced Abnormalities0low10
Drunkenness0low10
Dysacusis0low10
Encephalitis0low10
Encephalitis, Rasmussen0low10
Equine Diseases0low10
Fanconi Anemia0low10
Fanconi Hypoplastic Anemia0low10
Fanconi Pancytopenia0low10
Fanconi Panmyelopathy0low10
Fanconi's Anemia0low10
Feline Diseases0low10
Genotoxicant-Induced Micronuclei0low10
Hearing Disorders0low10
Heart Block0low10
Hemeralopia0low10
Horse Diseases0low10
Idiopathic Ventricular Tachycardia0low10
Inflammation, Brain0low10
Intestinal Obstruction0medium11
Intoxication, Alcoholic0low10
Irreversible Coma0low10
Late Effects, Prenatal Exposure0low10
Macropsia0low10
Malignancy0low10
Malignant Neoplasms0low10
Metamorphopsia0low10
Micronuclei, Chromosome-Defective0low10
Micronuclei, Genotoxicant-Induced0low10
Micronucleus, Chromosome-Defective0low10
Micropsia0low10
Muscle Contraction0low10
Necrosis0low10
Neoplasia0low10
Neoplasm0low10
Neoplasms0low10
Neoplasms, Benign0low10
Neoplasms, Prostate0low20
Neoplasms, Prostatic0low20
Nonsustained Ventricular Tachycardia0low10
Occupational Diseases0low10
Occupational Illnesses0low10
Organophosphate Poisoning0medium21
Organophosphorus Poisoning0medium21
Organothiophosphate Poisoning0medium21
Organothiophosphonate Poisoning0medium21
Ovine Diseases0low10
Palsy0low10
Paracousis0low10
Paracusis0low10
Paralysis0low10
Paroxysmal Supraventricular Tachycardia0low10
Plegia0low10
Poisoning0low30
Polyneuropathies0low10
Polyneuropathy, Acquired0low10
Polyneuropathy, Critical Illness0low10
Polyneuropathy, Familial0low10
Polyneuropathy, Inherited0low10
Polyneuropathy, Motor0low10
Poultry Diseases0low10
Pregnancy0low10
Prenatal Exposure Delayed Effects0low10
Prostate Cancer0low20
Prostate Neoplasms0low20
Prostatic Cancer0low20
Prostatic Neoplasms0low20
Pseudocoma0low20
Rasmussen Encephalitis0low10
Rasmussen Syndrome0low10
Rasmussen's Syndrome0low10
Sensitivity and Specificity0low10
Sheep Diseases0low10
Tachycardia, Ventricular0low10
Todd Paralysis0low10
Todd's Paralysis0low10
Tumors0low10
Ventricular Tachyarrhythmias0low10
Ventricular Tachycardia0low10
Vision Disability0low10
Vision Disorders0low10
Visual Disorders0low10
Visual Impairment0low10

Research Highlights

Safety/Toxicity (3)

ArticleYear
Assessment of the genotoxic effects of organophosphorus insecticides phorate and trichlorfon in human lymphocytes.
Environmental toxicology, Volume: 29, Issue: 5		2014
Hypersalinity acclimation increases the toxicity of the insecticide phorate in coho salmon (Oncorhynchus kisutch).
Environmental science & technology, May-15, Volume: 45, Issue: 10		2011
Genotoxic effects of some organophosphorous pesticides. I. Induction of micronuclei in bone marrow cells in rat.
Mutation research, Volume: 155, Issue: 3		1985
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Development of a solid phase extraction method for agricultural pesticides in large-volume water samples.
Talanta, Jun-15, Volume: 81, Issue: 4-5		2010
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (2)

ArticleYear
[Research the role of gulonic acid lactone in the five kinds of organic phosphorus pesticide detection].
Wei sheng yan jiu = Journal of hygiene research, Volume: 39, Issue: 2		2010
Synergism of insecticides by herbicides.
Science (New York, N.Y.), Aug-31, Volume: 181, Issue: 4102		1973
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (1)

ArticleYear
Metabonomics evaluation of urine from rats administered with phorate under long-term and low-level exposure by ultra-performance liquid chromatography-mass spectrometry.
Journal of applied toxicology : JAT, Volume: 34, Issue: 2		2014
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]