Proteins > NAD(P)H dehydrogenase [quinone] 1
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NAD(P)H dehydrogenase [quinone] 1
An NAD(P)H dehydrogenase [quinone] 1 that is encoded in the genome of mouse. [OMA:Q64669, PRO:DNx]
Synonyms
EC 1.6.5.2;
Azoreductase;
DT-diaphorase;
DTD;
Menadione reductase;
NAD(P)H:quinone oxidoreductase 1;
Phylloquinone reductase;
Quinone reductase 1;
QR1
Research
Bioassay Publications (19)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 18 (94.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (17)
Drugs with Other Measurements
DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health.Journal of natural products, , 08-25, Volume: 80, Issue:8, 2017
Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1.Bioorganic & medicinal chemistry letters, , 12-15, Volume: 27, Issue:24, 2017
Synthesis, molecular docking and anticancer studies of peptides and iso-peptides.Bioorganic & medicinal chemistry letters, , Aug-01, Volume: 25, Issue:15, 2015
Spongiapyridine and related spongians isolated from an Indonesian Spongia sp.Journal of natural products, , Jul-25, Volume: 77, Issue:7, 2014
Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles.European journal of medicinal chemistry, , Volume: 68, 2013
Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1).Bioorganic & medicinal chemistry, , Dec-15, Volume: 20, Issue:24, 2012
Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol.Bioorganic & medicinal chemistry, , Apr-01, Volume: 20, Issue:7, 2012
Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.Bioorganic & medicinal chemistry, , Nov-01, Volume: 19, Issue:21, 2011
Fijiolides A and B, inhibitors of TNF-alpha-induced NFkappaB activation, from a marine-derived sediment bacterium of the genus Nocardiopsis.Journal of natural products, , Jun-25, Volume: 73, Issue:6, 2010
Systemic structure-activity relationship study of phenyl polyyne diols as potential chemopreventive agents.Bioorganic & medicinal chemistry letters, , 10-15, Volume: 26, Issue:20, 2016
Identification of dialkyl diacetylene diols with potent cancer chemopreventive activity.Bioorganic & medicinal chemistry letters, , Sep-15, Volume: 25, Issue:18, 2015
Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284.Journal of medicinal chemistry, , Dec-23, Volume: 53, Issue:24, 2010
Functionalized 3-benzylidene-indolin-2-ones: inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1) with antiproliferative activity.Bioorganic & medicinal chemistry, , Mar-01, Volume: 17, Issue:5, 2009
Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents.Journal of medicinal chemistry, , Mar-24, Volume: 54, Issue:6, 2011
Synthesis and biological evaluation of 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]-4-ethynylimidazole. A novel and highly potent anti-inflammatory and cytoprotective agent.Bioorganic & medicinal chemistry letters, , Apr-15, Volume: 21, Issue:8, 2011
Spongiapyridine and related spongians isolated from an Indonesian Spongia sp.Journal of natural products, , Jul-25, Volume: 77, Issue:7, 2014
Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol.Bioorganic & medicinal chemistry, , Apr-01, Volume: 20, Issue:7, 2012
Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets.Bioorganic & medicinal chemistry, , Jan-01, Volume: 20, Issue:1, 2012
Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1).Bioorganic & medicinal chemistry, , Dec-15, Volume: 20, Issue:24, 2012
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.Bioorganic & medicinal chemistry letters, , Feb-01, Volume: 21, Issue:3, 2011
Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites.Journal of medicinal chemistry, , Jul-08, Volume: 53, Issue:13, 2010
Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents.Journal of medicinal chemistry, , Mar-24, Volume: 54, Issue:6, 2011
Synthesis and biological evaluation of 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]-4-ethynylimidazole. A novel and highly potent anti-inflammatory and cytoprotective agent.Bioorganic & medicinal chemistry letters, , Apr-15, Volume: 21, Issue:8, 2011
Synthesis and biological evaluation of biotin conjugates of (±)-(4bS,8aR,10aS)-10a-ethynyl-4b,8,8-trimethyl-3,7-dioxo-3,4b,7,8,8a,9,10,10a-octahydro-phenanthrene-2,6-dicarbonitrile, an activator of the Keap1/Nrf2/ARE pathway, for the isolation of its protBioorganic & medicinal chemistry letters, , Oct-15, Volume: 23, Issue:20, 2013
Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents.Journal of medicinal chemistry, , Mar-24, Volume: 54, Issue:6, 2011