Page last updated: 2024-11-05

2,4,7-trinitrofluorenone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,4,7-trinitrofluorenone: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID8521
CHEMBL ID164435
SCHEMBL ID55362
MeSH IDM0047308

Synonyms (40)

Synonym
9h-fluoren-9-one,4,7-trinitro-
nsc-12367
fluoren-9-one,4,7-trinitro-
wln: l b656 hvj cnw enw knw
2,7-trinitrofluoren-9-one
129-79-3
TNF ,
2,7-trinitrofluorenone
nsc12367
2,4,7-trinitrofluorenone
9h-fluoren-9-one, 2,4,7-trinitro-
nsc 12367
2,4,7-trinitrofluoren-9-one
hsdb 5408
2,4,7-trinitrofluorone
fluoren-9-one, 2,4,7-trinitro-
tnf (ketone)
einecs 204-965-0
ai3-17164
ccris 1298
STK366818
2,4,7-trinitro-fluoren-9-one
2,4,7-trinitro-9h-fluoren-9-one
CHEMBL164435
AKOS003601454
BBL001149
2,4,7-trinitro-9-fluorenone
T0499
b2290yt0wb ,
unii-b2290yt0wb
FT-0609938
2,4,7-trinitro-9h-fluoren-9-one [hsdb]
trinitro-9-fluorenone, 2,4,7-
2,4,7-trinitrofluorenone [mi]
SCHEMBL55362
2,4,7-trinitro-9h-fluoren-9-one #
DTXSID1026245
2,4,7-trinitro-9-fluorenone 10 microg/ml in cyclohexane
VS-00828
Q22133107

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" For the in vivo assay, male CD rats were dosed 3 times via intratracheal instillation, whereas for the in vitro study, rat lungs cut into small pieces were treated with test substances for 16 h without exogenous activation."( Comparison of DNA adduct detection between two enhancement methods of the 32P-postlabelling assay in rat lung cells.
Ong, T; Stewart, JD; Whong, WZ, 1992
)
0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID23442Partition coefficient (logP)1991Journal of medicinal chemistry, Feb, Volume: 34, Issue:2
Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity.
AID465365Mutagenic activity in Salmonella typhimurium TA98 assessed as increase in number of revertants at 0.002 ug/plate by Ames test absence of S9 fraction (Rvb=22+/- 4)2010Journal of natural products, Feb-26, Volume: 73, Issue:2
DNA-damaging, mutagenic, and clastogenic activities of gentiopicroside isolated from Cephalaria kotschyi roots.
AID200690Mutagenic activity in an Ames test on Salmonella Typhimurium TA98; Activity is log of revertants/nmol1991Journal of medicinal chemistry, Feb, Volume: 34, Issue:2
Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (25)

TimeframeStudies, This Drug (%)All Drugs %
pre-19909 (36.00)18.7374
1990's5 (20.00)18.2507
2000's5 (20.00)29.6817
2010's6 (24.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.09

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.09 (24.57)
Research Supply Index3.30 (2.92)
Research Growth Index4.38 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.09)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (3.85%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other25 (96.15%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]