Clindamycin is a lincosamide antibiotic that is used to treat bacterial infections. It works by preventing bacteria from producing proteins that are essential for their survival. Clindamycin is effective against a wide range of bacteria, including those that cause skin infections, pneumonia, and pelvic inflammatory disease. Clindamycin is typically taken by mouth or injected into a vein. It is also available as a topical cream or solution for skin infections. Clindamycin is a safe and effective medication for most people. However, it can cause side effects, such as diarrhea, nausea, and vomiting. In rare cases, clindamycin can cause serious side effects, such as Clostridium difficile-associated diarrhea (CDAD) and liver damage. It is important to talk to your doctor about the risks and benefits of clindamycin before taking it.'
Clindamycin: An antibacterial agent that is a semisynthetic analog of LINCOMYCIN. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
clindamycin : A carbohydrate-containing antibiotic that is the semisynthetic derivative of lincomycin, a natural antibiotic. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 446598 |
| CHEMBL ID | 1753 |
| SCHEMBL ID | 3154 |
| MeSH ID | M0004561 |
| PubMed CID | 2786 |
| CHEMBL ID | 10766 |
| CHEBI ID | 95137 |
| SCHEMBL ID | 12356681 |
| MeSH ID | M0004561 |
| Synonym |
|---|
| BIDD:GT0418 |
| AB01275425-01 |
| clindamycin & interleukin 12 |
| clinda & il-12 |
| methyl 7-chloro-6,7,8-trideoxy-6-{[(4r)-1-methyl-4-propyl-l-prolyl]amino}-1-thio-l-threo-alpha-d-galacto-octopyranoside |
| hsdb 3037 |
| clindamycinum [inn-latin] |
| 7-chlorolincomycin |
| l-threo-alpha-d-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2s-trans)- |
| l-threo-alpha-d-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-((((2s,4r)-1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio- |
| clindamycine [inn-french] |
| chlorlincocin |
| einecs 242-209-1 |
| 7-deoxy-7(s)-chlorolincomycin |
| 7-chloro-7-deoxylincomycin |
| u-21,251 |
| clindamicina [inn-spanish] |
| l-threo-d-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-l-2-pyrrolidinecarboxamido)-1-thio-, trans-alpha- |
| dalacine |
| 7(s)-chloro-7-deoxylincomycin |
| clinimycin |
| u-21251 |
| l-threo-.alpha.-d-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2s,4r)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- |
| chlolincocin |
| (2s,4r)-n-[(1s,2s)-2-chloro-1-[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide |
| 18323-44-9 |
| clindamycin |
| C06914 |
| clindamycin (usan/inn) |
| cldm |
| D00277 |
| HMS2089N16 |
| HMS2089A05 |
| A831786 |
| (2s,4r)-n-[(1s,2s)-2-chloranyl-1-[(2r,3r,4s,5r,6r)-6-methylsulfanyl-3,4,5-tris(oxidanyl)oxan-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide |
| (2s,4r)-n-[(1s,2s)-2-chloro-1-[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(methylthio)-2-oxanyl]propyl]-1-methyl-4-propyl-2-pyrrolidinecarboxamide |
| 7 chloro 7 deoxylincomycin |
| klindan 300 |
| unii-3u02el437c |
| klimicin |
| u 21251 |
| 3u02el437c , |
| clindamycin [usan:inn:ban] |
| clindaderm |
| CHEMBL1753 |
| clindamicina |
| clindamycinum |
| clindamycine |
| clindamycin [vandf] |
| l-threo-.alpha.-d-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2s-trans)- |
| clindamycin phosphate impurity e [ep impurity] |
| clindamycin [mart.] |
| clindamycin [who-dd] |
| clindamycin [mi] |
| clindamycin [hsdb] |
| clindamycin [usan] |
| clindamycin [inn] |
| clindamycin [green book] |
| AM84752 |
| SCHEMBL3154 |
| (2s,4r)-n-((1s,2s)-2-chloro-1-((2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2h-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide |
| AB01275425_02 |
| DTXSID2022836 , |
| methyl 7-chloro-6,7,8-trideoxy-6-({[(2s,4r)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl}amino)-1-thio-l-threo-alpha-d-galacto-octopyranoside |
| SR-05000001477-1 |
| HY-B1455 |
| clindamycin,(s) |
| KDLRVYVGXIQJDK-AWPVFWJPSA-N |
| CS-11147 |
| CCG-268941 |
| l-threo-a-d-galacto-octopyranoside, methyl7-chloro-6,7,8-trideoxy-6-[[[(2s,4r)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- |
| CS-0013163 |
| gtpl10607 |
| AKOS037515852 |
| (2s,4r)-n-[(1s,2s)-2-chloro-1-[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide |
| EN300-19736038 |
| clindamed oral drops |
| clindamycine (inn-french) |
| clindamycin (mart.) |
| g01aa10 |
| clinimycin (rescinded) |
| j01ff01 |
| methyl 7-chloro-6,7,8-trideoxy-6- |
| dtxcid102836 |
| d10af01 |
| clindamycin in 5 percent dextrose |
| clindamycinum (inn-latin) |
| clindamycini hydrochloridum |
| clindamicina (inn-spanish) |
| l-threo-?-d-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2s,4r)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- |
| AKOS005410727 |
| 7-cdl |
| methyl 7-chloro-6,7,8-trideoxy-6-[(1-methyl-4-propylprolyl)amino]-1-thiooctopyranoside |
| STK177246 |
| smr000677917 |
| MLS001183714 , |
| 1097774-72-5 |
| EN300-51913 |
| CHEMBL10766 |
| n-{2-chloro-1-[3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl}-1-methyl-4-propylpyrrolidine-2-carboxamide |
| HMS2231K05 |
| FT-0603212 |
| methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-l-2-pyrrolidinecarboxamido)-1-thio-l-threo-.alpha.-d-galacto-octopyranoside |
| HMS3372M13 |
| MLS006011824 |
| SCHEMBL12356681 |
| KDLRVYVGXIQJDK-UHFFFAOYSA-N |
| l-threo-.alpha.-d-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, (2s-trans)- |
| l-threo-d-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-l-2-pyrrolidinecarboxamido)-1-thio-, trans- .alpha.- |
| J-002328 |
| CHEBI:95137 |
| HMS3651N15 |
| n-(2-chloro-1-(3,4,5-trihydroxy-6-(methylthio)tetrahydro-2h-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide |
| Q27166924 |
| n-[2-chloro-1-[3,4,5-trihydroxy-6-(methylthio)-2-oxanyl]propyl]-1-methyl-4-propyl-2-pyrrolidinecarboxamide |
| DTXSID70860219 |
| CS-0291705 |
Clindamycin-based therapy was efficient in 111/133 cases (83%) and thus represents a reliable and safe alternative treatment option. Experiments with rabbits demonstrated no toxic effects on the retina after vitrectomy when the infusion fluid contained either 20 microgram/ml chloramphenicol saline or amikacin saline.
Clindamycin pharmacokinetics was compared in critically ill patients with sepsis and healthy volunteers. The pharmacokinetic properties of a single intravenous (IV) dose of clindamyin were determined in six wallabies.
Silver nanoparticle gel and clindamycin gel for the treatment of moderate severity of acne vulgaris when use in combination with 2.
| Excerpt | Reference | Relevance |
|---|---|---|
| "To assess the possibility that non-aminoglycoside antibiotics may adversely affect the nephrotoxicity of the new semisynthetic aminoglycoside netilmicin, we gave ampicillin, carbenicillin, methicillin, cefamandole, and clindamycin, either singly or in combination with netilmicin, at two dose concentrations in rats." | ( Nephrotoxicity of netilmicin in combination with non-aminoglycoside antibiotics. Hagstrom, GL; Luft, FC; Maxwell, DR; Sloan, RS; Yum, MN, 1978) | 0.26 |
| "Acute renal failure (ARF) occurred concomitantly with the administration of gentamicin in combination with clindamycin in three patients in whom no other known predisposing cause of ARF could be demonstrated." | ( Renal failure following gentamicin in combination with clindamycin. Butkus, DE; de Torrente, A; Terman, DS, 1976) | 0.26 |
| "The activity of recombinant gamma interferon (rIFN-gamma) in combination with either pyrimethamine or clindamycin was examined in a murine model of acute toxoplasmosis." | ( Activity of gamma interferon in combination with pyrimethamine or clindamycin in treatment of murine toxoplasmosis. Israelski, D; Remington, J, 1990) | 0.28 |
| "One hundred and one isolates representing five species of the Bacteroides fragilis group were examined for their susceptibility to amoxycillin and ticarcillin alone or in combination with clavulanic acid, as well as to cefoxitin, latamoxef (moxalactam), ceftizoxime, imipenem, chloramphenicol, clindamycin and metronidazole by the proposed NCCLS agar dilution method." | ( In-vitro activity of amoxycillin and ticarcillin in combination with clavulanic acid compared with that of new beta-lactam agents against species of the Bacteroides fragilis group. Bourgault, AM; Lamothe, F, 1986) | 0.27 |
| "189 bacterial strains were investigated for their in vitro sensitivity against ceftazidime (alone and in combination with another antibiotic)." | ( In vitro activity of ceftazidime in combination with other antibiotics. Littschwager, G; Simon, C, ) | 0.13 |
| "We investigated the antibacterial activity of clindamycin and lincomycin at 1/4 X minimum inhibitory concentration (MIC), 1 X MIC and 4 X MIC against a serum-resistant Staphylococcus aureus and a serum-resistant Staphylococcus epidermidis strain in broth, in serum with and without the presence of leukocytes and in Hank's medium in combination with leukocytes alone." | ( [Antibacterial activity of clindamycin and lincomycin in broth, serum, and in combination with polymorphonuclear leukocytes against Staphylococcus aureus and Staphylococcus epidermidis]. Bassler, M; Daschner, F; Just, HM; Richter, A; Zeller, H, ) | 0.13 |
| "Tobramycin in combination with clindamycin or lincomycin were used as systemic antibiotics in the treatment of 20 consecutive patients with septic peritonitis or intraabdominal sepsis, 10 of which were in septic shock." | ( High-dose tobramycin combined with clindamycin or lincomycin in the treatment of septic peritonitis and intraabdominal sepsis. Edén, T; Muth, L, 1981) | 0.26 |
| " Clindamycin, chloramphenicol, and ticarcillin, each in combination with gentamicin, are equally effective in therapy for intraabdominal or female genital tract sepsis." | ( Prospective, randomized comparative study of clindamycin, chloramphenicol, and ticarcillin, each in combination with gentamicin, in therapy for intraabdominal and female genital tract sepsis. Albritton, WL; Brunton, S; Buckwold, FJ; Gurwith, MJ; Harding, GK; Koss, JC; Marrie, TJ; Ronald, AR, 1980) | 0.26 |
| "To assess the potential efficacy of fleroxacin in combination with clindamycin or metronidazole in mixed aerobic and anaerobic infections, we used a rat model of intra-abdominal abscesses in which the inoculum consisted of pooled rat feces mixed with BaSO4." | ( Activity of fleroxacin alone and in combination with clindamycin or metronidazole in experimental intra-abdominal abscesses. Eliopoulos, GM; Ferraro, MJ; Holden, J; Moellering, RC; Pefanis, A; Thauvin-Eliopoulos, C, 1994) | 0.29 |
| "The efficacy of hyperbaric oxygen (HBO) alone and in combination with several antimicrobial agents was evaluated in a lethal model of gas gangrene in mice." | ( Evaluation of antimicrobials combined with hyperbaric oxygen in a mouse model of clostridial myonecrosis. Anderson, LH; Mehm, WJ; Muhvich, KH, 1994) | 0.29 |
| " Doses of each drug that were not effective in reducing inflammation in the brain of mice with toxoplasmic encephalitis when used alone were used in combination with a dose of rifabutin which was minimally effective." | ( Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice. Araujo, FG; Remington, JS; Suzuki, Y, 1996) | 0.29 |
| " Five days a week, the three materials (benzoyl peroxide, clindamycin phosphate, and erythromycin) were applied in a nonocclusive manner either alone or in combination with adapalene gel on seven cutaneous sites on the upper back." | ( Skin tolerance of adapalene 0.1% gel in combination with other topical antiacne treatments. Caron, D; Clucas, A; Sorba, V; Verschoore, M, 1997) | 0.3 |
| " The same dose protected 100% of infected mice when administered in combination with non-protective doses of atovaquone, clindamycin or sulphadiazine." | ( Use of ketolides in combination with other drugs to treat experimental toxoplasmosis. Araujo, FG; Bryskier, A; Khan, AA; Remington, JS, 1998) | 0.3 |
| "Using checkerboard and time-kill assays, the in-vitro activity of ciprofloxacin alone and in combination with flomoxef against clinical Bacteroides fragilis strains was evaluated." | ( In-vitro activity of ciprofloxacin combined with flomoxef against Bacteroides fragilis, compared with that of ciprofloxacin combined with clindamycin. Harada, T; Ito, Y; Iwai, S; Iwanaga, H; Kato, K; Nakagawa, Y; Sato, T; Takayama, T, 2002) | 0.31 |
| "A method for the quantification of clindamycin in animal plasma using high-performance liquid chromatography combined with electrospray ionization mass spectrometry (LC/ESI-MS/MS) is presented." | ( Determination of clindamycin in animal plasma by high-performance liquid chromatography combined with electrospray ionization mass spectrometry. Cherlet, M; Croubels, S; De Backer, P, 2002) | 0.31 |
| "The efficacy of atovaquone (ATO) combined with clindamycin (CLI) against Toxoplasma gondii was examined in murine models of infection with a mouse-non-virulent (Me49) strain." | ( Efficacy of atovaquone combined with clindamycin against murine infection with a cystogenic (Me49) strain of Toxoplasma gondii. Bobić, B; Djurković-Djaković, O; Grujić, J; Milenković, V; Nikolić, A, 2002) | 0.31 |
| "A group of 46 patients with acne vulgaris were prescribed clindamycin in combination with a vaccination therapy using a staphylococci antigenic complex (Polystafana; Sevapharma, Czechia)." | ( Effect of vaccination therapy for acne, using a staphylococci antigenic complex in combination with clindamycin. Dorko, E; Jautová, J; Pilipcinec, E; Tkáciková, L, 2003) | 0.32 |
| " This study was conducted to evaluate the antimalarial potential of clindamycin in combination with dihydroartemisinin in continuously cultured and in freshly isolated Plasmodium falciparum parasites, measuring the inhibition of Plasmodium falciparum histidine-rich protein II synthesis." | ( In vitro activity and interaction of clindamycin combined with dihydroartemisinin against Plasmodium falciparum. Graninger, W; Kremsner, PG; Noedl, H; Ramharter, M; Wernsdorfer, WH; Winkler, H; Winkler, S, 2003) | 0.32 |
| " Adapalene alone or in combination with clindamycin topical solution was well tolerated." | ( A successful maintenance approach in inflammatory acne with adapalene gel 0.1% after an initial treatment in combination with clindamycin topical solution 1% or after monotherapy with clindamycin topical solution 1%. Li, LF; Tu, YT; Zhang, JZ; Zheng, J, 2004) | 0.32 |
| "The in vitro antibacterial activity against antibiotic-resistant Propionibacterium acnes of kaempferol isolated from the Impatiens balsamina alone and in combination with erythromycin or clindamycin antibiotics was investigated." | ( In vitro activity of kaempferol isolated from the Impatiens balsamina alone and in combination with erythromycin or clindamycin against Propionibacterium acnes. Kim, IH; Lim, YH; Seo, JJ, 2007) | 0.34 |
| "The study shows that aggressive treatment of the patient with antibiotics combined with specific Lactobacillus strain administration and partner treatment can provide long lasting cure." | ( Extended antimicrobial treatment of bacterial vaginosis combined with human lactobacilli to find the best treatment and minimize the risk of relapses. Andersen, KK; Brandsborg, E; Forsum, U; Hammarström, L; Larsson, PG; Marcotte, H; Nasic, S; Pendharkar, S, 2011) | 0.37 |
| "The in vitro antimicrobial activities of usnic acid were evaluated in combination with five therapeutically available antibiotics, using checkerboard microdilution assay against methicillin-resistant clinical isolates strains of Staphylococcus aureus." | ( In vitro interaction of usnic acid in combination with antimicrobial agents against methicillin-resistant Staphylococcus aureus clinical isolates determined by FICI and ΔE model methods. Amicosante, G; Bellio, P; Brisdelli, F; Celenza, G; Garbarino, JA; Nicoletti, M; Perilli, M; Piovano, M; Segatore, B; Setacci, D, 2012) | 0.38 |
| "A total of 30 chalcone analogues was synthesized via a base catalyzed Claisen Schmidt condensation and screened for their in vitro antibacterial activity against Methicillin-sensitive Staphylococcus aureus (MSSA) and Methicillin-resistant Staphylococcus aureus (MRSA) alone or in combination with non beta-lactam antibiotics namely ciprofloxacin, chloramphenicol, erythromycin, vancomycin, doxycycline and gentamicin." | ( Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. Do, TH; Huynh, TN; Ngo, TD; Thai, KM; Tran, CD; Tran, NC; Tran, TD, 2012) | 0.38 |
| "2% (T/CP) gel in combination with a benzoyl peroxide 6% foaming cloth compared with T/CP alone for facial acne." | ( Efficacy and safety of tretinoin 0.025%/clindamycin phosphate 1.2% gel in combination with benzoyl peroxide 6% cleansing cloths for the treatment of facial acne vulgaris. Haddican, M; Linkner, RV; Wong, V; Zeichner, JA, 2013) | 0.39 |
| " Patients who received either vancomycin monotherapy or vancomycin in combination with clindamycin were included." | ( Vancomycin Combined With Clindamycin for the Treatment of Acute Bacterial Skin and Skin-Structure Infections. English, TM; McCreary, EK; Wargo, KA, 2015) | 0.42 |
| "Caspofungin combined with clindamycin is an optional treatment for PCP when treatment with TMP-SMZ fails or in patients who cannot tolerate TMP-SMZ." | ( Successful treatment of severe Pneumocystis pneumonia in an immunosuppressed patient using caspofungin combined with clindamycin: a case report and literature review. He, H; Huang, H; Li, H, 2016) | 0.43 |
| " Besides, compared to dauricine alone, combined with clindamycin had more remarkably effects on severe pneumonia in vitro." | ( Dauricine combined with clindamycin inhibits severe pneumonia co-infected by influenza virus H5N1 and Streptococcus pneumoniae in vitro and in vivo through NF-κB signaling pathway. Chen, X; Li, H; Zhou, SJ, 2018) | 0.48 |
| " There are no studies demonstrating the immunomodulatory effect of clindamycin in combination with ceftriaxone in a clinically relevant murine polymicrobial sepsis model induced by cecal ligation and puncture (CLP)." | ( Immunomodulatory dose of clindamycin in combination with ceftriaxone improves survival and prevents organ damage in murine polymicrobial sepsis. Mokale, SN; Patel, AM; Periasamy, H, 2020) | 0.56 |
| " In an attempt to prevent PTB in singleton pregnancies, cervical cerclage, in combination with other treatments, has been advocated." | ( Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies. Eke, AC; Eleje, GU; Ezebialu, IU; Ikechebelu, JI; Ilika, CP; Okam, PC, 2020) | 0.56 |
| " We included studies comparing cervical cerclage in combination with one, two or more interventions with cervical cerclage alone in singleton pregnancies." | ( Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies. Eke, AC; Eleje, GU; Ezebialu, IU; Ikechebelu, JI; Ilika, CP; Okam, PC, 2020) | 0.56 |
| " One study (20 women), conducted in the UK, comparing cervical cerclage in combination with a tocolytic (salbutamol) with cervical cerclage alone in women with singleton pregnancy did not provide any useable data for this review." | ( Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies. Eke, AC; Eleje, GU; Ezebialu, IU; Ikechebelu, JI; Ilika, CP; Okam, PC, 2020) | 0.56 |
| " We did not identify any studies looking at other treatments in combination with cervical cerclage." | ( Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies. Eke, AC; Eleje, GU; Ezebialu, IU; Ikechebelu, JI; Ilika, CP; Okam, PC, 2020) | 0.56 |
Clindamycin is an antimicrobial agent with excellent bioavailability after oral administration. It has been considered for the therapy of community-acquired pneumococcal otitis media. The current study was focused to develop a stabilised clind amycin.
| Excerpt | Reference | Relevance |
|---|---|---|
| "The effect of a kaolin--pectin antidiarrheal suspension on the bioavailability of orally administered clindamycin was evaluated by model-dependent pharmacokinetic techniques." | ( Pharmacokinetic evaluation of a drug interaction between kaolin--pectin and clindamycin. Albert, KS; DeSante, KA; DiSanto, AR; Welch, RD, 1978) | 0.26 |
| " This difference is attributed to differences in bioavailability and/or binding characteristics of the drugs for bioreceptors, as a consequence of structural modifications in the drug molecules, and to differences in modes of action in the respective organisms." | ( Microbial kinetics of drug action against gram-positive and gram-negative organisms. III: Effect of lincomycin and clindamycin combinations on Staphylococcus aureus and Escherichia coli. Heman-Ackah, SM, 1975) | 0.25 |
| " Bioavailability after IM administration was 87%." | ( Pharmacokinetics of clindamycin phosphate in dogs after single intravenous and intramuscular administrations. Budsberg, SC; Kemp, DT; Wolski, N, 1992) | 0.28 |
| " However, these data, in concert with knowledge of drug bioavailability in feces and the broad-spectrum antimicrobial activity on the resident bowel flora, may provide additional insight into the mechanisms and predictability of this complication with these agents." | ( In vitro susceptibility of Clostridium difficile to new beta-lactam and quinolone antibiotics. Bartlett, KH; Cheng, N; Chow, AW, 1985) | 0.27 |
| " Correlation of these data with other literature data suggests a possible relationship between clindamycin bioavailability and clinical efficacy in the treatment of acne and, therefore, argues against extemporaneous compounding of this drug in the absence of bioavailability data." | ( On the bioavailability of topical formulations of clindamycin hydrochloride. Franz, TJ, 1983) | 0.27 |
| " Daily oral administration of poorly absorbed cephalosporins protected hamsters from clindamycin-induced cecitis and death as long as the cephalosporins were continued." | ( Evaluation of eight cephalosporins in hamster colitis model. Ebright, JR; Fekety, R; Silva, J; Wilson, KH, 1981) | 0.26 |
| " The drug has excellent bioavailability and good penetration in most tissues, including the cerebrospinal fluid and brain abscess contents." | ( Clindamycin and metronidazole. Falagas, ME; Gorbach, SL, 1995) | 0.29 |
| " This may have been because of increased bioavailability of the drug or increased sensitivity of the receptors." | ( Acute verapamil toxicity in a patient with chronic toxicity: possible interaction with ceftriaxone and clindamycin. Jonas, E; Kishore, K; Misra, V; Raina, A, ) | 0.13 |
| "The absolute oral bioavailability and pharmacokinetics of clindamycin administered to 16 healthy volunteers and 16 patients with AIDS were compared." | ( Comparative study of bioavailabilities and pharmacokinetics of clindamycin in healthy volunteers and patients with AIDS. Borin, M; Bubp, J; Flaherty, J; Gambertoglio, J; Gatti, G; White, J, 1993) | 0.29 |
| " Clindamycin is an antimicrobial agent with excellent bioavailability after oral administration which has been considered for the therapy of community-acquired pneumococcal otitis media." | ( Clindamycin resistance among erythromycin-resistant Streptococcus pneumoniae. Cormican, MG; Jones, RN; Wanger, A, 1996) | 0.29 |
| " The method has been successfully applied to the bioavailability study of two commercial preparations of clindamycin phosphate injection (300 mg each) in twelve healthy adult male volunteers." | ( High-performance liquid chromatographic determination of clindamycin in human plasma or serum: application to the bioequivalency study of clindamycin phosphate injections. Chen, YK; Hsieh, SY; Hung, MH; Lin, ET; Liu, CM; Yang, TH, 1997) | 0.3 |
| "The absolute bioavailability of clindamycin phosphate vaginal ovule with comparison to a reference treatment of clindamycin phosphate sterile solution, as well as the relative bioavailability of the ovule compared to clindamycin phosphate vaginal cream, was evaluated in 12 healthy adult female volunteers." | ( Systemic absorption of clindamycin after intravaginal administration of clindamycin phosphate ovule or cream. Borin, MT; Hopkins, NK; Ryan, KK, 1999) | 0.3 |
| "The study was conducted to investigate the pharmacokinetics and relative bioavailability of clindamycin after administration of two oral clindamycin HCl formulations." | ( Bioavailability and selected pharmacokinetic parameters of clindamycin hydrochloride after administration of a new 600 mg tablet formulation. Blume, HH; Evers, G; Fieger-Büschges, H; Gimbel, W; Keilbach-Bermann, A; Larsimont, V; Mazur, D; Schug, BS, 1999) | 0.3 |
| " All of these older drugs are well absorbed by the oral route, attaining serum levels equivalent to those achieved by parenteral administration." | ( New uses of older antibiotics. Cunha, BA; Klein, NC, 2001) | 0.31 |
| " The antibiotics should be well absorbed after oral administration, have a high intrinsic activity against the offending pathogen, and be given at intervals leading to inhibitory blood concentrations throughout most of the day." | ( [Long-term antibiotic suppressive therapy for an infected thoracic aorta graft]. Berdal, JE; Steinbakk, M, 2003) | 0.32 |
| "Oral bioavailability and pharmacokinetic behaviour of clindamycin in dogs was investigated following intravenous (IV) and oral (capsules) administration of clindamycin hydrochloride, at the dose of 11 mg/kg BW." | ( Clindamycin bioavailability and pharmacokinetics following oral administration of clindamycin hydrochloride capsules in dogs. Athanasiou, LV; Batzias, GC; Delis, GA, 2005) | 0.33 |
| "The purpose of this study was to compare the systemic bioavailability of clindamycin from 1 dose of CSDVC with that from 1 dose from a 7-day regimen of CVC in healthy women." | ( An open-label, two-period, crossover study of the systemic bioavailability in healthy women of clindamycin phosphate from two vaginal cream formulations. Gattermeir, DJ; Joffrion, JL; Levinson, RS; Mitan, SJ; Schumacher, RJ; Steinmetz, JI, 2005) | 0.33 |
| " Overall bioavailability of clindamycin from CSDVC was approximately 12% of that from CVC, as measured by AUC." | ( An open-label, two-period, crossover study of the systemic bioavailability in healthy women of clindamycin phosphate from two vaginal cream formulations. Gattermeir, DJ; Joffrion, JL; Levinson, RS; Mitan, SJ; Schumacher, RJ; Steinmetz, JI, 2005) | 0.33 |
| "Systemic bioavailability of clindamycin was significantly lower and systemic absorption was significantly slower with the CSDVC formulation than with the single dose of 7-day CVC formulation in these healthy volunteers." | ( An open-label, two-period, crossover study of the systemic bioavailability in healthy women of clindamycin phosphate from two vaginal cream formulations. Gattermeir, DJ; Joffrion, JL; Levinson, RS; Mitan, SJ; Schumacher, RJ; Steinmetz, JI, 2005) | 0.33 |
| " The aim of this investigation was to compare the bioavailability of a single, intramuscular injection, of 2 ml." | ( Bioequivalence study of clindamycin phosphate injection (Clinott-P) in Thai healthy volunteers. Ayudhya, DP; Kasattut, N; Leelarasamee, A; Sriboonruang, T; Tatong, W, 2006) | 0.33 |
| " As zinc/clindamycin gel is a topical treatment for acne, the lower systemic bioavailability may be beneficial because there may be a correspondingly lower risk of systemic events in zinc/clindamycin gel-treated subjects." | ( A single centre, open-label, cross-over study of pharmacokinetics comparing topical zinc/clindamycin gel (Zindaclin) and topical clindamycin lotion (Dalacin T) in subjects with mild to moderate acne. Chassard, D; Evene, E; Kanis, R; Namour, F; Ntssikoussalabongui, B; Schmitz, V, 2006) | 0.33 |
| " Hence, the extent of absolute oral bioavailability (F) was also independent of oral doses." | ( Dose-independent pharmacokinetics of clindamycin after intravenous and oral administration to rats: contribution of gastric first-pass effect to low bioavailability. Lee, MG; Yang, SH, 2007) | 0.34 |
| " A solubilized formulation of BPO has been developed to maximize its bioavailability and enhance follicular penetration." | ( Solubilized benzoyl peroxide versus benzoyl peroxide/clindamycin in the treatment of moderate acne. Dhawan, S; Kircik, L; Tanghetti, E; Wilson, D, 2008) | 0.35 |
| "The aim of the present study was to compare the bioavailability of clindamycin (CAS 18323-44-9) from three clindamycin hydrochloride (CAS 21 462-39-5) capsules (clindamycin 75 mg capsule as test 1 preparation, 150 mg capsule as test 2 preparation and a commercially available original 150 mg capsule of the drug as reference preparation) in 24 Chinese healthy male volunteers, aged between 22 and 28." | ( Pharmacokinetics and bioequivalence study of clindamycin hydrochloride formulations after single-dose administration in healthy Chinese male volunteers. Chen, Y; Li, J; Tang, W; Tian, Y; Wang, N; Zhang, ZJ, 2008) | 0.35 |
| "A 3-step acne system has been developed to enhance the bioavailability and follicular penetration of benzoyl peroxide (BPO)." | ( A 3-step acne system containing solubilized benzoyl peroxide versus clindamycin-benzoyl peroxide. Del Rosso, JQ; Eichenfield, L; Parr, L; Shalita, A; Swinyer, L; Tanghetti, E; Thiboutot, D; Tschen, E, 2009) | 0.35 |
| "Oral bioavailability (F) is a product of fraction absorbed (Fa), fraction escaping gut-wall elimination (Fg), and fraction escaping hepatic elimination (Fh)." | ( Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV, 2010) | 0.36 |
| " cis-Mirincamycin had an absolute oral bioavailability of 13." | ( Absolute bioavailability of cis-mirincamycin and trans-mirincamycin in healthy rhesus monkeys and ex vivo antimalarial activity against Plasmodium falciparum. Fracisco, S; Imerbsin, R; Khemawoot, P; Melendez, V; Ohrt, C; Rasameesoraj, M; Saunders, D; Teja-Isavadharm, P, 2011) | 0.37 |
| " The poor efficacy observed for the F/C combination may be a consequence of the new formulations used, differential bioavailability in younger children, naturally occurring variations in parasite sensitivity to the drugs, or an insufficient enhancement of their effects by naturally acquired immunity in young children." | ( Inadequate efficacy of a new formulation of fosmidomycin-clindamycin combination in Mozambican children less than three years old with uncomplicated Plasmodium falciparum malaria. Alonso, P; Bassat, Q; Cisteró, P; González, R; Hutchinson, D; Kremsner, PG; Lanaspa, M; Macete, E; Machevo, S; Mayor, A; Menéndez, C; Moraleda, C; Serrano, B, 2012) | 0.38 |
| " The typical population estimates (interindividual variability) for clearance, volume of distribution and absorption rate constant were 16." | ( Population pharmacokinetics of clindamycin orally and intravenously administered in patients with osteomyelitis. Bouazza, N; Curis, E; Jullien, V; Pestre, V; Salmon, D; Tréluyer, JM; Urien, S, 2012) | 0.38 |
| " This antibiotic is bactericidal and is orally bioavailable in mice." | ( Structure-activity relationship for the oxadiazole class of antibiotics. Antunes, NT; Boudreau, MA; Chang, M; Ding, D; Lastochkin, E; Leemans, E; Lichtenwalter, K; Mobashery, S; O'Daniel, PI; Peng, Z; Pi, H; Schroeder, VA; Song, W; Spink, E; Suckow, MA; Testero, SA; Vakulenko, S; Wolter, WR, 2015) | 0.42 |
| " The current study was focused to develop a stabilised clindamycin encapsulated poly lactic acid (PLA)/poly (D,L-lactide-co-glycolide) (PLGA) nano-formulation with better drug bioavailability at molecular level." | ( Enhanced efficacy of clindamycin hydrochloride encapsulated in PLA/PLGA based nanoparticle system for oral delivery. Ashe, S; Das, NM; Nayak, B; Nayak, D; Rauta, PR, 2016) | 0.43 |
| "Clindamycin has high bioavailability together with good diffusion in bone tissue and could represent an alternative antibiotic compound for the treatment of bone and joint infections (BJIs)." | ( Efficacy and safety of clindamycin-based treatment for bone and joint infections: a cohort study. Bernard, E; Courjon, J; Cua, E; Demonchy, E; Roger, PM, 2017) | 0.46 |
| " Extracted parameters included bioavailability for oral drugs, volume of distribution (Vd) and clearance (CL), trough and peak drug concentrations, time of maximum concentration, area under the curve and half-life, probability of target attainment, and minimal inhibitory concentration (MIC)." | ( The Pharmacokinetics and Target Attainment of Antimicrobial Drugs Throughout Pregnancy: Part III Non-penicillin and Non-cephalosporin Drugs. Groen, F; Hooge, MNL; Kosterink, JGW; Mian, P; Prins, JR; Touw, DJ; Winter, HLJ, 2023) | 0.91 |
| " Prospective studies evaluating bioavailability of antimicrobial agents after oral administration in SBS patients are lacking." | ( Oral antimicrobial agents in patients with short bowel syndrome: worth a try! Brüggemann, RJM; Gompelman, M; Jager, NGL; Korzilius, JW; Rovers, CP; Wanten, GJA; Wezendonk, GTJ, 2023) | 0.91 |
| "To determine the bioavailability of orally administered antimicrobial agents commonly used for treatment in SBS patients to guide clinical decision making when faced with infections." | ( Oral antimicrobial agents in patients with short bowel syndrome: worth a try! Brüggemann, RJM; Gompelman, M; Jager, NGL; Korzilius, JW; Rovers, CP; Wanten, GJA; Wezendonk, GTJ, 2023) | 0.91 |
| " Primary outcome was the oral bioavailability of these antimicrobial agents." | ( Oral antimicrobial agents in patients with short bowel syndrome: worth a try! Brüggemann, RJM; Gompelman, M; Jager, NGL; Korzilius, JW; Rovers, CP; Wanten, GJA; Wezendonk, GTJ, 2023) | 0.91 |
| " The median observed (IQR) bioavailability of ciprofloxacin, clindamycin, flucloxacillin and fluconazole were 36% (24-50), 93% (56-106), 50% (32-76) and 98% (61-107), respectively." | ( Oral antimicrobial agents in patients with short bowel syndrome: worth a try! Brüggemann, RJM; Gompelman, M; Jager, NGL; Korzilius, JW; Rovers, CP; Wanten, GJA; Wezendonk, GTJ, 2023) | 0.91 |
| "The bioavailability of selected antimicrobial agents in certain patients with SBS appeared to be better than expected, providing a feasible treatment option." | ( Oral antimicrobial agents in patients with short bowel syndrome: worth a try! Brüggemann, RJM; Gompelman, M; Jager, NGL; Korzilius, JW; Rovers, CP; Wanten, GJA; Wezendonk, GTJ, 2023) | 0.91 |
Once-daily gentamicin dosing with twice-daily clindamycin dosing is as efficacious and safe as the thrice-daily dosing of gentamic in for peripar. Cytosorb® hemoadsorption during Panton-Valentine leucocidin producing methicillin-resistant Staphylococcus aureus infection appears safe.
| Class | Description |
|---|---|
| proline derivative | An amino acid derivative resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of proline by a heteroatom. The definition normally excludes peptides containing proline residues. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 0.4108 | 0.0041 | 10.8903 | 31.5287 | AID504467 |
| geminin | Homo sapiens (human) | Potency | 6.5131 | 0.0046 | 11.3741 | 33.4983 | AID624297 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Protein-arginine deiminase type-4 | Homo sapiens (human) | IC50 (µMol) | 5,100.0000 | 2.5000 | 4.2000 | 5.9000 | AID320706 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 (µMol) | 0.0600 | 0.0600 | 8.9128 | 130.5170 | AID1902 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| chromatin organization | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| nucleosome assembly | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| chromatin remodeling | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| stem cell population maintenance | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| protein modification process | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| post-translational protein modification | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| innate immune response | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| protein-arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| calcium ion binding | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| protein binding | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| identical protein binding | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone H3R2 arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone H3R8 arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone H3R17 arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| histone H3R26 arginine deiminase activity | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| nucleus | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| nucleoplasm | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| cytosol | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| protein-containing complex | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| nucleus | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| cytoplasm | Protein-arginine deiminase type-4 | Homo sapiens (human) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1347411 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7 | High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID533365 | Antimicrobial activity against Bacteroides uniformis by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID562363 | Antimicrobial activity against penicillin-resistant Streptococcus pneumoniae clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID278497 | Antibacterial activity against Pneumococcus DAW67 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID557718 | Antimicrobial activity in Fusobacterium mortiferum by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID342087 | Effect on growth of epidemic Clostridium difficile BI6-8-17 in CF1 mouse assessed as increase in bacterial density in cecal content at 2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID768031 | Antibacterial activity against Staphylococcus aureus expressing NorA by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID522154 | Antimicrobial activity against Fusobacterium nucleatum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID522189 | Antimicrobial activity against Mogibacterium timidum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID531564 | Antibacterial activity against methicillin-susceptible, coagulase-negative Staphylococcus obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID425083 | Antimicrobial activity against beta lactamase-positive Prevotella nigrescens isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID508367 | Antibacterial activity against penicillin-resistant Streptococcus pneumoniae after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID528728 | Antibacterial activity against Streptococcus pyogenes group A clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID557944 | Antimicrobial activity in Bifidobacterium by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID571797 | Antibacterial activity against Clostridium bartlettii by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID531568 | Antibacterial activity against Streptococcus pyogenes obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID548737 | Antimicrobial activity against Oxacillin-susceptible Staphylococcus aureus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID433009 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolated from patient with diabetic foot infection after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID433013 | Antibacterial activity against Staphylococcus lugdunensis isolated from patient with diabetic foot infection after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID542385 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ST398 expressing cfr, fexA, erm(A), tet(M) and mecA genes | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID574524 | Antimicrobial activity against Prevotella oralis after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID206675 | In vitro antibacterial activity against the aerobic Staphylococcus mitis (Strain UC no.153) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID559492 | Antibacterial activity against Clostridium perfringens assessed as percent susceptible isolates by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID1870138 | Antibacterial activity against wild type methicillin resistant Staphylococcus aureus 4968/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID508436 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 3009 harboring mutation in 23S rRNA after 20 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID531515 | Antibacterial activity against Bacteroides distasonis assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID508460 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2094 harboring erm(A) gene after 5 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID278503 | Antibacterial activity against Pneumococcus CDC013 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID425079 | Antimicrobial activity against beta lactamase-positive Bacteroides distasonis isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID516162 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as susceptible isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID561727 | Antibacterial activity against Enterococcus faecium assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID206907 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.746) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID278665 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5737 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID571830 | Antibacterial activity against Ruminococcus gnavus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID508434 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 7127 harboring S20N mutation in L4 ribosomal protein and A105V mutation in L22 ribosomal protein after 43 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID571831 | Antibacterial activity against Ruminococcus obeum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID508468 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2011 harboring mef(A) gene after 50 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID573824 | Antibacterial activity against beta-lactamase producing Clostridium septicum by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID1879489 | Antibacterial activity against Actinomyces naeslundii ATCC 1210 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID528730 | Antibacterial activity against penicillin resistant Streptococcus pneumoniae clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID535018 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-3 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID1079935 | Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source] | |||
| AID571813 | Antibacterial activity against Clostridium tertium by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID41429 | In vitro activity against thetaiotaomicron (ATCC 29741) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID522173 | Antimicrobial activity against Peptoniphilus harei under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID520733 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring plasmid MS2 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. |
| AID425084 | Antimicrobial activity against beta lactamase-positive Prevotella melaninogenica isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID571768 | Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-I626M mutant gene | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID522155 | Antimicrobial activity against Fusobacterium necrophorum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID571812 | Antibacterial activity against Clostridium sporosphaeroides by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID573596 | Antibacterial activity against Fusobacterium mortiferum assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID433370 | Antibacterial activity against Peptostreptococcus anaerobius isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID534343 | Antimicrobial activity against Burkholderia pseudomallei Bp173 harboring mini-Tn7T after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID533421 | Antimicrobial activity against Anaerococcus prevotii by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID574532 | Antimicrobial activity against Prevotella bivia assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID522193 | Antimicrobial activity against Lactobacillus rhamnosus under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID534441 | Antimicrobial activity against Clostridium septicum ATCC 12464 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID531526 | Antibacterial activity against Bacteroides distasonis isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID534471 | Antimicrobial activity against Bacteroides thetaiotaomicron ATCC 29741 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID422652 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3665 after 14 passages with Telithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID534786 | Antimicrobial activity against community-acquired methicillin-resistant Staphylococcus aureus by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID327752 | Antibacterial activity against Staphylococcus aureus Smith infected iv dosed mouse septicemia model | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Novel antibacterial azetidine lincosamides. |
| AID535020 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-17 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID670955 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 at 2 ug/disc after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. |
| AID565080 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus 56 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Pharmacodynamic profile of tigecycline against methicillin-resistant Staphylococcus aureus in an experimental pneumonia model. |
| AID565757 | Antimicrobial activity against oxacillin-susceptible Staphylococcus epidermidis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID522178 | Antimicrobial activity against Actinomyces odontolyticus under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID520962 | Antimicrobial activity against Corynebacterium xerosis isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID369231 | Antibacterial activity against constitutive macrolide-lincosamide-streptogramin B-resistant Streptococcus pneumoniae isolates by double-disk diffusion method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID508385 | Antibacterial activity against Streptococcus pyogenes harboring mutation in L4 ribosomal protein after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID425100 | Antimicrobial activity against Peptoniphilus asaccharolyticus isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID557793 | Antimicrobial activity against Streptococcus pyogenes clinical isolate expressing mef(A) gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Characterization of macrolide efflux pump mef subclasses detected in clinical isolates of Streptococcus pyogenes isolated between 1999 and 2005. |
| AID586038 | Antimicrobial activity against Staphylococcus aureus clone 1-1 harboring staphylococcal cassette chromosome mec element type U assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID528702 | Antibacterial activity against Streptococcus constellatus clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID528727 | Antibacterial activity against Streptococcus agalactiae group B clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID557948 | Antimicrobial activity in Propionibacterium acnes by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID625288 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID508374 | Antibacterial activity against Streptococcus pneumoniae harboring mutation in 23S rRNA after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID555310 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis 225 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID571991 | Antibacterial activity against Ruminococcus sp. by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1241207 | Inhibition of pre-miR-373 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID404935 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus isolate by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID565291 | Antimicrobial activity against Mycoplasma hominis by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | In vitro activity of a new quinoline derivative, ER-2, against clinical isolates of Mycoplasma pneumoniae and Mycoplasma hominis. |
| AID571764 | Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring acrB::rpsLneo mutant gene | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID534432 | Antimicrobial activity against Peptoniphilus indolicus GAI 0915 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID508379 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae harboring erm(B) and mef(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID520392 | Antibacterial activity against mef and erm(B) positive Streptococcus pneumoniae isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID520607 | Antimicrobial activity against Group D Streptococcus sp. clinical isolates expressing erm(T) gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Prevalence of the erm(T) gene in clinical isolates of erythromycin-resistant group D Streptococcus and Enterococcus. |
| AID528844 | Antimicrobial activity against penicillin-resistant Streptococcus pneumoniae assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID206768 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.570) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID574975 | Antimicrobial activity against Actinomyces meyeri after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID404900 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB40 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID565730 | Antimicrobial activity against Streptococcus Group F clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID322791 | Antimicrobial activity against Bacteroides merdae assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID519996 | Antimicrobial activity against Streptococcus pneumoniae harboring mef(A) gene | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID574750 | Antimicrobial activity against Peptostreptococcus micros assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID322790 | Antimicrobial activity against Bacteroides eggerthii assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID574746 | Antimicrobial activity against Peptostreptococcus anaerobius assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID574782 | Antimicrobial activity against Actinomyces odontolyticus after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID522160 | Antimicrobial activity against Anaerococcus tetradius under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID565753 | Antimicrobial activity against oxacillin-resistant Staphylococcus haemolyticus clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID557436 | Antimicrobial activity in Prevotella bivia by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID571827 | Antibacterial activity against Eggerthella lenta by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID50845 | In vitro antibacterial activity against the anaerobic Clostridium difficile (Strain UC no.6858) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID520292 | Antimicrobial activity against Staphylococcus aureus 2549 small colony variants | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID1079947 | Comments (NB not yet translated). [column 'COMMENTAIRES' in source] | |||
| AID433154 | Antibacterial activity against Porphyromonas asaccharolyticus isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID342245 | Increase in toxin level in epidemic Clostridium difficile BI9 infected CF1 mouse at 0.2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID285348 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20020488 in CCY medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID522197 | Antimicrobial activity against Clostridium clostridioforme under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID561254 | Antibacterial activity against Streptococcus pyogenes assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID572007 | Antibacterial activity against Bacteroides splanchnicus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID508381 | Antibacterial activity against macrolide-susceptible Streptococcus pyogenes after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID535639 | Antimicrobial activity against Group B streptococcus serotype VI R1 harboring F395L, V405A, R433H, H438Y, and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID547760 | Antimicrobial activity against invasive Streptococcus intermedius obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on brain heart infusion agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID561513 | Antibacterial activity against Beta-hemolytic Streptococcus group B by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID571824 | Antibacterial activity against Colinsella aerofaciens by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID531551 | Antibacterial activity against Staphylococcus aureus obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID125739 | Bioactivity in abscess, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 90 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID50994 | In vitro antibacterial activity against the anaerobic Clostridium perfringens (Strain UC no.6509) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID522139 | Antimicrobial activity against Bacteroides vulgatus under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID531558 | Antibacterial activity against coagulase-negative Staphylococcus capitis obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID125735 | Bioactivity in abscess, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 30 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID495936 | Antimicrobial activity against erythromycin, inducible lincomycin, inducible clindamycin resistant Staphylococcus haemolyticus isolate 31UL harboring ermC gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID520959 | Antimicrobial activity against Corynebacterium pseudodiphtheriticum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID573601 | Antibacterial activity against Fusobacterium necrophorum assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID534474 | Antimicrobial activity against Bacteroides ureolyticus NCTC 10941 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID555292 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID562608 | Antimicrobial activity against penicillin-susceptible Streptococcus pneumoniae clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID528838 | Antimicrobial activity against vancomycin-resistant Enterococcus sp. assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID1870144 | Antibacterial activity against wild type Staphylococcus aureus 4883/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID562376 | Antimicrobial activity against Streptococcus pyogenes clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID571998 | Antibacterial activity against Streptococcus anginosus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID561234 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID573590 | Antibacterial activity against Fusobacterium varium by by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID533377 | Antimicrobial activity against Bacteroides merdae by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID540212 | Mean residence time in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID574778 | Antimicrobial activity against Clostridium difficile assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID1870150 | Antibacterial activity against wild type Staphylococcus aureus 4740/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID285514 | Antibacterial activity against Bacteroides fragilis by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID561244 | Antibacterial activity against methicillin-susceptible Staphylococcus epidermidis assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID516169 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as resistant isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID561515 | Antibacterial activity against Enterococcus faecium by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID50993 | In vitro antibacterial activity against the anaerobic Clostridium perfringens (Strain UC no.247) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID586056 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 6 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID369228 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae assessed as percent resistant isolates by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID522164 | Antimicrobial activity against Peptostreptococcus anaerobius under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID531575 | Antibacterial activity against Bacillus spp. obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID508466 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2094 harboring erm(A) gene after 34 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID554541 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC879 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID528973 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID572000 | Antibacterial activity against Streptococcus intermedius by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID548745 | Antimicrobial activity against Beta-hemolytic Streptococcus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID369448 | Antimicrobial activity against Streptococcus viridans after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID521966 | Antibacterial activity against Campylobacter jejuni assessed as resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID565729 | Antimicrobial activity against erythromycin-susceptible Streptococcus Group F clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID548253 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID508402 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 3665 harboring mef(A) gene after 14 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID1870142 | Antibacterial activity against wild type Staphylococcus aureus 4904/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID585160 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA C2499U mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID574977 | Antimicrobial activity against Actinomyces meyeri assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID433168 | Antibacterial activity against Peptoniphilus asaccharolyticus isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID554548 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC720 preincubated with 2 ug/ml erythromycin for 20 to 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID557968 | Antimicrobial activity in Clostridium sp. by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID278509 | Antibacterial activity against Pneumococcus CDC068 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID528731 | Antibacterial activity against penicillin intermediate Streptococcus pneumoniae clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID1241209 | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID534446 | Antimicrobial activity against Bifidobacterium bifidum JCM 1255 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID534680 | Antimicrobial activity against Capnocytophaga ochracea GAI 5586 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID522142 | Antimicrobial activity against Prevotella melaninogenica under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID557794 | Antimicrobial activity against Streptococcus pyogenes clinical isolate expressing mef(E) gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Characterization of macrolide efflux pump mef subclasses detected in clinical isolates of Streptococcus pyogenes isolated between 1999 and 2005. |
| AID574514 | Antimicrobial activity against Bacteroides ovatus assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID433157 | Antibacterial activity against Clostridium perfringens isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID574969 | Antimicrobial activity against Actinomyces israelii after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID433161 | Antibacterial activity against Clostridium innocuum isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID561236 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID278869 | Decrease in lactate production in HeLa cells by ELISA | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID404902 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID586050 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type U8 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID573798 | Antibacterial activity against Prevotella melaninogenica assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID520963 | Antimicrobial activity against Arcanobacterium haemolyticum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID1879557 | Antibacterial activity against Clostridium sporogenes ATCC 19404 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID278489 | Antibacterial activity against Pneumococcus DAW27 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID322996 | Antibacterial activity against drug-resistant Propionibacterium acnes EG13NS after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID574027 | Antibacterial activity against beta-lactamase producing Peptostreptococcus anaerobius assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID323030 | Antibacterial activity against Staphylococcus epidermidis after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID528706 | Antibacterial activity against Streptococcus agalactiae group B clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID278666 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5739 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID571996 | Antibacterial activity against Peptostreptococcus anaerobius by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID533369 | Antimicrobial activity against Bacteroides vulgatus by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID531576 | Antibacterial activity against Gemella morbillorum obtained from complicated skin and skin structure infections by RapID ANA system | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID574744 | Antimicrobial activity against Peptostreptococcus anaerobius assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID425082 | Antimicrobial activity against beta lactamase-positive Prevotella intermedia isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID528724 | Antibacterial activity against Streptococcus oralis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID561261 | Antibacterial activity against Enterococcus faecalis by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID572006 | Antibacterial activity against Bacteroides vulgatus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID534672 | Antimicrobial activity against Porphyromonas asaccharolyticus ATCC 25260 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID555307 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis 057 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID557440 | Antimicrobial activity in Prevotella buccae by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID565731 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus Group G clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID533662 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring vgaAv positive plasmid CU1 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID404896 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB28 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID404950 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus sp. assessed as percent susceptible isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID1424066 | Antibiotic activity against methicillin-resistant Staphylococcus aureus isolate CAIRD116 by broth microdilution assay or Alamar blue dye based colorimetric assay | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture. |
| AID573825 | Antibacterial activity against beta-lactamase producing Clostridium tertium by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID534462 | Antimicrobial activity against Bacteroides fragilis NCTC 10581 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID522167 | Antimicrobial activity against Anaerococcus murdochii under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID533405 | Antimicrobial activity against Clostridium tertium by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID571927 | Ratio of MIC for Escherichia coli K-12 3-AG300 harboring acrB::rpsLneo mutant gene to MIC for Escherichia coli K-12 3-AG300 | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID573573 | Antibacterial activity against beta-lactamase producing Bacteroides uniformis assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID573551 | Antibacterial activity against Bacteroides fragilis assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID516165 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates by CLSi method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID1879558 | Antibacterial activity against rifampicin-resistant Clostridium difficile MMX 3587 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID342259 | Inhibition of clindamycin-susceptible epidemic Clostridium difficile NAP1 in CF1 mouse at 0.2 mg/day, sc for 5 days | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID433167 | Antibacterial activity against Finegoldia magna isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID557416 | Antimicrobial activity in Bacteroides ovatus by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID573581 | Antibacterial activity against beta-lactamase producing Bacteroides caccae by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID278500 | Antibacterial activity against Pneumococcus DAW75 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID574752 | Antimicrobial activity against Anaerococcus prevotii after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID562602 | Antimicrobial activity against Staphylococcus epidermidis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID285340 | Antibacterial activity against Staphylococcus aureus LUG855 in Mueller-Hinton medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID534793 | Bactericidal activity against community-acquired methicillin-resistant Staphylococcus aureus assessed as antibiotic concentration that reduced the number of viable cells by =>99.9% by colony count method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID372517 | Antimalarial activity as 3rd generation parasitaemia against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 96hrs at 25 nM dosed 0-12 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID534669 | Antimicrobial activity against Prevotella denticola GAI 5490 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID522150 | Antimicrobial activity against Prevotella oris under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID574987 | Antimicrobial activity against Bifidobacterium adolescentis after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID433162 | Antibacterial activity against Clostridium malenominatum isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID534791 | Bactericidal activity against vancomycin-resistant Staphylococcus aureus assessed as antibiotic concentration that reduced the number of viable cells by =>99.9% by colony count method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID554542 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC958 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID562408 | Antimicrobial activity against penicillin-resistant Streptococcus pneumoniae clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID585169 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA G2032A, U2504G mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID372477 | Antimalarial activity as abnormal apicoplast morphology in chloroquine-sensitive ACP1-GFP-labeled Plasmodium falciparum 3D7 trophozoite infected human erythrocytes at 2xIC50 dosed 96 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID574999 | Antimicrobial activity against Eubacterium lentum after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID520958 | Antimicrobial activity against Corynebacterium minutissimum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID522136 | Antimicrobial activity against Bacteroides merdae under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID555297 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus aureus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID163245 | In vitro antibacterial activity against the aerobic Proteus vulgaris (Strain UC no.93) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID1459983 | In vivo antiparasitic activity against Pneumocystis sp. assessed as parasite clearance time | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Comprehensive review on various strategies for antimalarial drug discovery. |
| AID1474166 | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring severity class index | 2016 | Drug discovery today, Apr, Volume: 21, Issue:4 | DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. |
| AID739298 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as growth inhibition by CLSI broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. |
| AID574758 | Antimicrobial activity against Peptoniphilus asaccharolyticus after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID554547 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC719 preincubated with 2 ug/ml erythromycin for 20 to 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID528837 | Antimicrobial activity against vancomycin-resistant Enterococcus sp. isolated from ICU patient urine assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID422659 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1077 after 29 passages with azithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID583893 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus isolate 435 by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID522141 | Antimicrobial activity against Prevotella buccae under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID522199 | Antimicrobial activity against Clostridium bolteae under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID522147 | Antimicrobial activity against Prevotella disiens under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID562402 | Antimicrobial activity against Streptococcus pneumoniae clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID572012 | Antibacterial activity against Prevotella buccae by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID561740 | Antibacterial activity against Beta-hemolytic Streptococcus group A assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID571931 | Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-615-628MexB-S623N mutant gene | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID285156 | Antimicrobial activity against Streptococcus pneumoniae ATCC 49619 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland. |
| AID404947 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate assessed as percent resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID508407 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 1076 harboring erm(B) and mef(A) gene after 18 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID561724 | Antibacterial activity against Enterococcus faecium assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID574546 | Antimicrobial activity against community-associated methicillin-resistant Staphylococcus aureus Sanger 252 | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID433188 | Antibacterial activity against Corynebacterium simulans isolated from patient with diabetic foot infection assessed as percent resistant isolates after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID369435 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID425095 | Antimicrobial activity against Finegoldia magna isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID694205 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus 8325-4 by CLSI broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 22, Issue:22 | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. |
| AID572015 | Antibacterial activity against Prevotella P disiens by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID520964 | Antimicrobial activity against Rhodococcus equi isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID531530 | Antibacterial activity against Bacteroides thetaiotaomicron isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID574023 | Antibacterial activity against beta-lactamase producing Peptostreptococcus anaerobius by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID572020 | Antibacterial activity against Prevotella melaninogenica by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID361254 | Growth inhibition as apicoplast copy number of Plasmodium falciparum FCK2 at 100 nM by [3H]hypoxanthine uptake | 2007 | The Journal of biological chemistry, Mar-02, Volume: 282, Issue:9 | 15-deoxyspergualin primarily targets the trafficking of apicoplast proteins in Plasmodium falciparum. |
| AID534443 | Antimicrobial activity against Clostridium ramosum ATCC 25582 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID571995 | Antibacterial activity against Peptoniphilus asaccharolyticus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID285527 | Antibacterial activity against Peptostreptococcus sp. by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID508403 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 3665 harboring mef(A) gene after 50 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID571825 | Antibacterial activity against Coprobacillus cateniformis by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID571795 | Antibacterial activity against Clostridium ramosum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID533409 | Antimicrobial activity against Finegoldia magna by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID404898 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB33 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID768033 | Antibacterial activity against Bacillus cereus ATCC 11778 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID562374 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus pyogenes clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID285342 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20020488 in Mueller-Hinton medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID575084 | Antimicrobial activity against multiple drug resistant Streptococcus pneumoniae serotype 6B assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID533660 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring plasmid VGA | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID596017 | Antiparasitic activity against clindamycin-resistant Toxoplasma gondii 4 infected in HFF assessed as reduction of ycf24/UPRT genes copy number ratio at 1 uM treated for 48 hrs immediately after infection followed by reinoculated into fresh HFF monolayers | 2011 | Journal of medicinal chemistry, Apr-28, Volume: 54, Issue:8 | Chemistry and biology of macrolide antiparasitic agents. |
| AID206895 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6675) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID323031 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID583888 | Antibacterial activity against hospital-associated methicillin-resistant Staphylococcus aureus isolate 336 by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID1879552 | Antibacterial activity against Bacteroides vulgatus MMX 8348 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID323026 | Antibacterial activity against Corynebacterium jeikeium after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID557730 | Antimicrobial activity in Micromonas micros by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID433185 | Antibacterial activity against Corynebacterium urealyticum isolated from patient with diabetic foot infection assessed as percent resistant isolates after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID561241 | Antibacterial activity against methicillin-susceptible Staphylococcus epidermidis by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID424424 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus AIS2006032 isolated from patients foot wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID557698 | Antimicrobial activity in Prevotella loescheii by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID574764 | Antimicrobial activity against Finegoldia magna after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID522146 | Antimicrobial activity against Prevotella denticola under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID520396 | Antibacterial activity against mef(E) and mef(A)-positive Streptococcus pneumoniae isolate CC-6B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID557726 | Antimicrobial activity in Finegoldia magna by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID534438 | Antimicrobial activity against Clostridium clostridioforme NCTC 11224 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID1230065 | Antibacterial activity against methicillin-resistant Staphylococcus aureus GRE2372 assessed as inhibition of bacterial growth | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. |
| AID425075 | Antimicrobial activity against beta lactamase-positive Bacteroides fragilis isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID433376 | Antibacterial activity against Anaerococcus vaginalis isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID571810 | Antibacterial activity against Clostridium spiroforme by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID572005 | Antibacterial activity against Bacteroides thetaiotaomicron by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID575080 | Antimicrobial activity against Streptococcus pneumoniae serotype 11A assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID433164 | Antibacterial activity against Propionibacterium acnes isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID1879565 | Antibacterial activity against Peptococcus niger ATCC 27731 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID562224 | Antimicrobial activity against Desulfovibrio piger by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID574740 | Antimicrobial activity against Peptostreptococcus anaerobius after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID557448 | Antimicrobial activity in Prevotella denticola by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID530122 | Antimicrobial activity against hospital acquired methicillin-resistant Staphylococcus aureus 149 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. |
| AID1625274 | Antimalarial activity against Plasmodium falciparum W2 after 48 hrs | 2016 | Journal of medicinal chemistry, 06-23, Volume: 59, Issue:12 | Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action. |
| AID571819 | Antibacterial activity against Bifidobacterium dentium by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID574482 | Antimicrobial activity against Bacteroides fragilis after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID574543 | Activity of Quorum sensing agr in community-associated methicillin-resistant Staphylococcus aureus USA300 assessed as PSMalpha expression after 8 hrs by qRT-PCR | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID125734 | Bioactivity in abscess, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 150 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID522149 | Antimicrobial activity against Prevotella nanceiensis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID571793 | Antibacterial activity against Clostridium innocuum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID125736 | Bioactivity in abscess, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 360 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID520961 | Antimicrobial activity against Corynebacterium urealyticum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID425653 | Renal clearance in human | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15 | Physicochemical determinants of human renal clearance. |
| AID535026 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-26 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID547532 | Antimicrobial activity against Streptococcus intermedius obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of 5% defri | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID425969 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 2527 after 20 passages with azithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID555299 | Antibacterial activity against Tmp-resistant coagulase-negative Staphylococcus aureus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID522181 | Antimicrobial activity against Propionibacterium avidum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID425089 | Antimicrobial activity against Porphyromonas gingivalis isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID683715 | Antimalarial activity against Plasmodium vivax assessed as effect on cure rate after 28 days | 2012 | Journal of medicinal chemistry, Feb-09, Volume: 55, Issue:3 | Targeting the liver stage of malaria parasites: a yet unmet goal. |
| AID581653 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient in cation-adjusted MH 2 broth assessed as log reduction of extracellular CFU after 5 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID125738 | Bioactivity in abscess, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 60 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID561501 | Antibacterial activity against methicillin-resistant Staphylococcus aureus | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Characterization of ermA in macrolide-susceptible strains of methicillin-resistant Staphylococcus aureus. |
| AID520734 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus CM05 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. |
| AID1879547 | Antibacterial activity against Bacteroides fragilis ATCC 25285 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID71152 | In vitro antibacterial activity against the anaerobic Eubacterium limosum(Strain UC no.6515) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID562372 | Antimicrobial activity against erythromycin-susceptible Streptococcus Group C clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID573598 | Antibacterial activity against Fusobacterium varium assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID571804 | Antibacterial activity against Clostridium hypermegas by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID572017 | Antibacterial activity against Prevotella intermedia by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID361256 | TufA expression level in Plasmodium falciparum FCK2 first asexual cycle | 2007 | The Journal of biological chemistry, Mar-02, Volume: 282, Issue:9 | 15-deoxyspergualin primarily targets the trafficking of apicoplast proteins in Plasmodium falciparum. |
| AID531571 | Antibacterial activity against Streptococcus constellatus obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID535260 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-8 expressing SCCmec element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID433366 | Antibacterial activity against Anaerococcus prevotii isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID562223 | Antimicrobial activity against Desulfovibrio desulfuricans MB by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID739303 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 assessed as growth inhibition by CLSI broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. |
| AID520393 | Antibacterial activity against mef-positive Streptococcus pneumoniae isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID565081 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus 152 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Pharmacodynamic profile of tigecycline against methicillin-resistant Staphylococcus aureus in an experimental pneumonia model. |
| AID285161 | Antimicrobial activity against non replicating persistence Mycobacterium tuberculosis H37Rv in anaerobic condition assessed as relative light unit after 11 days by LORA assay | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. |
| AID323007 | Antibacterial activity against drug-resistant Propionibacterium acnes SW101T after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID369445 | Antibacterial activity against penicillin-resistant Streptococcus pneumoniae after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID1079949 | Proposed mechanism(s) of liver damage. [column 'MEC' in source] | |||
| AID372478 | Antimalarial activity as parasitaemia against chloroquine-sensitive ACP1-GFP-labeled Plasmodium falciparum 3D7 trophozoite infected human erythrocytes at 2xIC50 dosed 96 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID1424068 | Antibiotic activity against methicillin-resistant Staphylococcus aureus isolate CAIRD148 by broth microdilution assay or Alamar blue dye based colorimetric assay | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture. |
| AID323010 | Antibacterial activity against drug-resistant Propionibacterium acnes GE4E after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID575275 | Antimicrobial activity against Clostridium difficile by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates. |
| AID533425 | Antimicrobial activity against Peptostreptococcus sp. by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID283557 | Antimicrobial activity against Streptococcus pneumoniae R6 with L4 69GTG71 to TPS mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID534795 | Antimicrobial activity against vancomycin-intermediate Staphylococcus aureus by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID567567 | Antimicrobial activity against Bacillus sp. BS-01 expressing multiple resistance gene cfr and phenolic resistance gene fexA obtained from swine feces | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. |
| AID571833 | Antibacterial activity against Ruminococcus flavefaciens by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID508376 | Antibacterial activity against quinolone-resistant Streptococcus pneumoniae after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID278670 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5735 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID285159 | Antimicrobial activity against non replicating persistence Mycobacterium tuberculosis H37Rv in aerobic condition assessed by relative light units after 7 days | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. |
| AID373749 | Antimicrobial activity against mupirocin-susceptible methicillin-resistant Staphylococcus aureus assessed as resistant rate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. |
| AID531562 | Antibacterial activity against coagulase-negative Staphylococcus warneri obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID444053 | Renal clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID278487 | Antibacterial activity against Pneumococcus DAW24 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID718415 | Antibacterial activity against log-phase methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as growth inhibition after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Dec-15, Volume: 20, Issue:24 | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. |
| AID573783 | Antibacterial activity against Prevotella buccae by by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID285346 | Antibacterial activity against Staphylococcus aureus LUG855 in CCY media | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID559495 | Antibacterial activity against Prevotella sp. assessed as percent susceptible isolates by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID571791 | Antibacterial activity against Clostridium difficile by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID528968 | Antimicrobial activity against methicillin-susceptible Staphylococcus epidermidis assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID562600 | Antimicrobial activity against oxacillin-resistant Staphylococcus epidermidis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID534476 | Antimicrobial activity against Sutterella wadsworthensis ATCC 51579 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID558086 | Antimicrobial activity against Mycoplasma hominis isolated from human by two fold serial dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101. |
| AID522179 | Antimicrobial activity against Actinomyces turicensis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID433155 | Antibacterial activity against Porphyromonas somerae isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID1879564 | Antibacterial activity against Mobiluncus mulieris ATCC 35243 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID565741 | Antimicrobial activity against erythromycin-susceptible Streptococcus agalactiae clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID534452 | Antimicrobial activity against Propionibacterium granulosum ATCC 25564 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID285526 | Antibacterial activity against Propionibacterium acnes | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID530124 | Antimicrobial activity against community acquired methicillin-resistant Staphylococcus aureus 147 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. |
| AID531528 | Antibacterial activity against Bacteroides caccae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID533131 | Antimicrobial activity against Bacteroides fragilis by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID571818 | Antibacterial activity against Bifidobacterium breve by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID425093 | Antimicrobial activity against Fusobacterium varium isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID495937 | Antimicrobial activity against erythromycin, inducible lincomycin, inducible clindamycin resistant Staphylococcus epidermidis isolate 32PL harboring ermC gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID571809 | Antibacterial activity against Clostridium sordellii by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID433364 | Antibacterial activity against Clostridium sphenoides isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID206898 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6688) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID433201 | Antibacterial activity against Bacteroides stercoris isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID528704 | Antibacterial activity against Streptococcus intermedius clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID327745 | Antibacterial activity against Streptococcus pneumoniae by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Novel antibacterial azetidine lincosamides. |
| AID508375 | Antibacterial activity against quinolone-susceptible Streptococcus pneumoniae after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID534346 | Antimicrobial activity against Burkholderia pseudomallei Bp207 harboring deleted (bpeAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID425103 | Antimicrobial activity against Clostridium innocuum isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID548522 | Antimicrobial activity against Oxacillin-susceptible Staphylococcus aureus assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID372518 | Antimalarial activity as 3rd generation parasitaemia against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 96hrs at 25 nM dosed 0-24 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID433375 | Antibacterial activity against Anaerococcus vaginalis isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID573563 | Antibacterial activity against beta-lactamase producing Bacteroides vulgatus by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID520740 | Antimicrobial activity against erm(B)-deficient Staphylococcus aureus RN4220 harboring cfr gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. |
| AID51139 | In vitro antibacterial activity against the anaerobic Clostridium tertium(Strain UC no.6508) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID433020 | Antibacterial activity against Bacteroides stercoris isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID373747 | Antimicrobial activity against mupirocin-susceptible methicillin-resistant Staphylococcus aureus by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. |
| AID533128 | Antimicrobial activity against Bacteroides caccae by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID572008 | Antibacterial activity against Bilophila wadsworthia by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID206896 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6686) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID433358 | Antibacterial activity against Clostridium perfringens isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID522131 | Antimicrobial activity against Bacteroides fragilis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID522148 | Antimicrobial activity against Prevotella loescheii under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID372524 | Antimalarial activity as 3rd generation parasitaemia against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 96hrs at 25 nM dosed 24-36 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID562397 | Antimicrobial activity against oxacillin-susceptible Staphylococcus aureus clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID531522 | Antibacterial activity against Bacteroides merdae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID322781 | Antimicrobial activity against Bacteroides stercoris isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID540237 | Phospholipidosis-positive literature compound observed in rat | |||
| AID571801 | Antibacterial activity against Clostridium celerecrescens by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID540239 | Phospholipidosis-positive literature compound observed in dog | |||
| AID574518 | Antimicrobial activity against Prevotella intermedia after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID323005 | Antibacterial activity against drug-resistant Propionibacterium acnes P429:1 (BC) after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID342242 | Increase in toxin level in epidemic Clostridium difficile BI6-8-17 infected CF1 mouse at 1.4 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID575005 | Antimicrobial activity against Eubacterium sp. after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID545046 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ085 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID278495 | Antibacterial activity against Pneumococcus DAW65 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID531554 | Antibacterial activity against coagulase-negative Staphylococcus epidermidis obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID557694 | Antimicrobial activity in Prevotella salivae by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID425099 | Antimicrobial activity against Anaerococcus tetradius isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID424320 | Antimicrobial activity against Dialister micraerophilus by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID557412 | Antimicrobial activity in Bacteroides thetaiotaomicron by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID571997 | Antibacterial activity against Peptostreptococcus micros by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID50842 | In vitro activity against Clostridium difficile (ATCC 9689) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID562375 | Antimicrobial activity against erythromycin-susceptible Streptococcus pyogenes clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1906418 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27883 assessed as reduction in microbial growth incubated for 24 hrs by microbroth dilution method | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Amphiphilic cyclic peptide [W |
| AID533663 | Antimicrobial activity against Staphylococcus aureus RN1024 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID571803 | Antibacterial activity against Clostridium glycolicum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID559490 | Antibacterial activity against Propionibacterium acnes by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID574985 | Antimicrobial activity against Actinomyces naeslundii assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID548527 | Antimicrobial activity against Oxacillin-susceptible coagulase-negative Staphylococcus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1879571 | Antibacterial activity against Prevotella bivia MMX 3450 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID555302 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID572016 | Antibacterial activity against Prevotella P intermedia by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID561752 | Antibacterial activity against Methicillin-resistant Staphylococcus aureus assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID285515 | Antibacterial activity against Clostridium difficile by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID581659 | Fraction unbound in human plasma | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID322999 | Antibacterial activity against drug-resistant Propionibacterium acnes EG3NS after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID573591 | Antibacterial activity against Fusobacterium nucleatum by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID557408 | Antimicrobial activity in Bacteroides fragilis by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID433365 | Antibacterial activity against Propionibacterium acnes isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID1879549 | Antibacterial activity against metronidazole-resistant Bacteroides thetaiotaomicron MMX 3409 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID534428 | Antimicrobial activity against Atopobium parvulum VPI 0546 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID534461 | Antimicrobial activity against Bacteroides fragilis ATCC 25285 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID560247 | Antibacterial activity against Staphylococcus aureus RN4220 by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID571807 | Antibacterial activity against Clostridium paraputrificum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID425102 | Antimicrobial activity against Clostridium difficile isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID522212 | Antimicrobial activity against Clostridium sphenoides under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID519995 | Antimicrobial activity against Streptococcus pneumoniae harboring erm(B) and mef(A) gene | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID128552 | Bioactivity in blood, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 150 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID531565 | Antibacterial activity against Enterococcus faecalis obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID583891 | Antibacterial activity against vancomycin-heteroresistant Staphylococcus aureus isolate 38 (Mu3) by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID422650 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3665 after 38 passages with moxifloxacin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID559494 | Antibacterial activity against Peptostreptococcus sp. assessed as percent susceptible isolates by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID548528 | Antimicrobial activity against Oxacillin-resistant coagulase-negative Staphylococcus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID278491 | Antibacterial activity against Pneumococcus DAW53 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID548534 | Antimicrobial activity against viridans group Streptococcus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID574995 | Antimicrobial activity against Bifidobacterium sp. assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID562399 | Antimicrobial activity against Streptococcus Group F clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID534677 | Antimicrobial activity against Bilophila wadsworthia WAL 7959 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID322774 | Antimicrobial activity against Bacteroides distasonis isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID508365 | Antibacterial activity against penicillin-susceptible Streptococcus pneumoniae after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID534477 | Antimicrobial activity against Prevotella bivia ATCC 29303 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID528722 | Antibacterial activity against Streptococcus viridans clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID535633 | Antimicrobial activity against Group B streptococcus serotype Ia R7 harboring T77I, F395V and S353F in PBP 2X; V80A and G613R in PBP 2B; and L45P, N163K, N723S and Y470F in PBP 1A by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID524825 | Antibacterial activity against erythromycin susceptible Campylobacter sp. by agar plate dilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID533125 | Antimicrobial activity against Bacteroides distasonis by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID586039 | Antimicrobial activity against Staphylococcus aureus clone 1-1 harboring staphylococcal cassette chromosome mec element type 4 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID425087 | Antimicrobial activity against beta lactamase-positive Prevotella buccae isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID508409 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 1076 harboring erm(B) and mef(A) gene after 14 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID41249 | In vitro activity against Bacteroides fragilis (105AT25285) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID534470 | Antimicrobial activity against Bacteroides ovatus ATCC 8483 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID572002 | Antibacterial activity against Parabacteroides merdae by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID571800 | Antibacterial activity against Clostridium butyricum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID323022 | MBC/MIC ratio of Propionibacterium acnes SW3CD | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID533360 | Antimicrobial activity against Bacteroides ovatus assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID323023 | MBC/MIC ratio of Propionibacterium acnes P95 | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID369447 | Antimicrobial activity against Streptococcus group B after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID433003 | Antibacterial activity against Corynebacterium minutissimum isolated from patient with diabetic foot infection after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID531553 | Antibacterial activity against methicillin susceptible Staphylococcus aureus obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID425974 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 24 after 50 passages with moxifloxacin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID574051 | Antibacterial activity against beta-lactamase producing Finegoldia magna assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID535008 | Antimicrobial activity against daptomycin-nonsusceptible Staphylococcus aureus by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID670958 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 after 24 hrs by microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. |
| AID342096 | Increase in toxin level in nonepidemic Clostridium difficile ATCC 9689 infected in CF1 mouse at 1.4 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID571798 | Antibacterial activity against Clostridium beijerinckii by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID540210 | Clearance in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID561729 | Antibacterial activity against Enterococcus faecalis assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID574776 | Antimicrobial activity against Clostridium difficile after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID535262 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-10 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID571794 | Antibacterial activity against Clostridium perfringens by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID531563 | Antibacterial activity against methicillin-resistant, oxacillin-susceptible, coagulase-negative, mecA-positive Staphylococcus lugdunensis obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID424616 | Antibacterial activity against Enterococcus avium AIS2007004 isolated from patients rectum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID584971 | Antibacterial activity against Mycobacterium smegmatis SZ558 after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID522161 | Antimicrobial activity against Finegoldia magna under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID562601 | Antimicrobial activity against oxacillin-susceptible Staphylococcus epidermidis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID561253 | Antibacterial activity against Streptococcus pyogenes by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID573552 | Antibacterial activity against Bacteroides fragilis assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID522152 | Antimicrobial activity against Porphyromonas asaccharolyticus under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID519066 | Antibacterial activity against multidrug resistant Streptococcus pneumoniae ATCC 49619 by CLSI microdilution susceptibility testing method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Activity of the Diaminopyrimidine AR-709 against recently collected multidrug-resistant isolates of invasive Streptococcus pneumoniae from North America. |
| AID574488 | Antimicrobial activity against Bacteroides distasonis after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID585171 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA C2055A, U2504G mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID522151 | Antimicrobial activity against Prevotella tannerae under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID554536 | Antimicrobial activity against Mycobacterium abscessus isolate MC1028 on day 4 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID768032 | Antibacterial activity against Mycobacterium smegmatis str. MC2 155 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID529879 | Antimicrobial activity against Enterococcus faecalis JH2-2 harboring empty vector by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID531556 | Antibacterial activity against coagulase-negative Staphylococcus lugdunensis obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID559859 | Antimicrobial activity against Streptococcus agalactiae clinical isolates by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections. |
| AID508382 | Antibacterial activity against Streptococcus pyogenes harboring erm(B) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID522166 | Antimicrobial activity against Anaerococcus lactolyticus under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID535001 | Antimicrobial activity against vancomycin-intermediate Staphylococcus aureus assessed as susceptible isolates by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID433165 | Antibacterial activity against Anaerococcus prevotii isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID718416 | Antibacterial activity against log-phase methicillin-sensitive Staphylococcus aureus 8325-4 assessed as growth inhibition after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Dec-15, Volume: 20, Issue:24 | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. |
| AID495935 | Antimicrobial activity against erythromycin, lincomycin, clindamycin resistant Staphylococcus epidermidis isolate 44KR harboring ermC gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID558014 | Antimicrobial activity in Porphyromonas gingivalis by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID533126 | Antimicrobial activity against Bacteroides caccae assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID555298 | Antibacterial activity against Tmp-susceptible coagulase-negative Staphylococcus aureus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID534457 | Antimicrobial activity against Lactobacillus plantarum JCM 1149 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID555499 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis 051 after 50 passages by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID41250 | In vitro activity against Bacteroides fragilis (784) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID50992 | In vitro activity against Clostridium perfringens (SFBC 2026) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID433357 | Antibacterial activity against Prevotella bivia isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID531573 | Antibacterial activity against Staphylococcus intermedius obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID508441 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 1076 harboring erm(B) and mef(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID565735 | Antimicrobial activity against erythromycin-susceptible Streptococcus Group C clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID565736 | Antimicrobial activity against Streptococcus Group C clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID433193 | Antibacterial activity against Staphylococcus haemolyticus isolated from patient with diabetic foot infection assessed as percent resistant isolates after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID571994 | Antibacterial activity against Finegoldia magna by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID585173 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA C2055A, A2572U mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID534433 | Antimicrobial activity against Peptostreptococcus anaerobius ATCC 27337 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID522163 | Antimicrobial activity against Peptoniphilus asaccharolyticus under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID571828 | Antibacterial activity against Holdemania filiformis by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1241205 | Inhibition of pre-miR-372 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID562357 | Antimicrobial activity against Streptococcus pneumoniae clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID522203 | Antimicrobial activity against Clostridium bifermentans under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID520960 | Antimicrobial activity against Corynebacterium striatum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID562396 | Antimicrobial activity against oxacillin-resistant Staphylococcus aureus clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID571990 | Antibacterial activity against Ruminococcus torques by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID565192 | Antimicrobial activity against Acinetobacter baumannii JVAB01 expressing disrupted open reading frame orf3 mutant deficient in efflux pump CraA by Etest | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii. |
| AID322775 | Antimicrobial activity against Bacteroides ovatus isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID369227 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae by microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID422686 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 37 after 14 passages with Telithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID433151 | Antibacterial activity against Bacteroides vulgatus isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID557722 | Antimicrobial activity in Fusobacterium varium by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID508373 | Antibacterial activity against Streptococcus pneumoniae harboring mutation in L4 ribosomal protein after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID522209 | Antimicrobial activity against Clostridium hylemonae under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID1870159 | Antibacterial activity against wild type Staphylococcus aureus 78/CF assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID425092 | Antimicrobial activity against Fusobacterium necrophorum isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID561257 | Antibacterial activity against Streptococcus agalactiae by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID571993 | Antibacterial activity against Anaerococcus tetradius by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID160396 | In vitro antibacterial activity against the anaerobic Propionibacterium acnes(Strain UC no.6564) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID548475 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID560250 | Antibacterial activity against Staphylococcus aureus RN4220 harboring aadD and tet(L) gene by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID1870136 | Antibacterial activity against antibiotic resistant Staphylococcus aureus 77/CF assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID574948 | Antimicrobial activity against Streptococcus pneumoniae serotype 19A by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID535012 | Antimicrobial activity against daptomycin-nonsusceptible Staphylococcus aureus assessed as resistant isolates by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID571989 | Antibacterial activity against Ruminococcus productus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID557652 | Antimicrobial activity against Mycobacterium abscessus isolate MC958 at day 7 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID444055 | Fraction absorbed in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID572018 | Antibacterial activity against Prevotella nigrescens by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID555315 | Antibacterial activity against methicillin-susceptible, vancomycin-intermediate Staphylococcus aureus 505 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID519999 | Antimicrobial activity against Streptococcus pyogenes harboring mef(A) gene | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID508423 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2686 harboring mutation in L4 ribosomal protein after 25 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID534437 | Antimicrobial activity against Streptococcus intermedius ATCC 27335 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID157242 | In vitro activity against Peptococcus asaccharolyticus (ATCC 14963). | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID1906414 | Antibacterial activity against Methicillin resistant Staphylococcus aureus ATCC BAA -1556 assessed as reduction in microbial growth incubated for 24 hrs by microbroth dilution method | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Amphiphilic cyclic peptide [W |
| AID497966 | Antimalarial activity against Plasmodium falciparum clinical isolate after 6 days by HRP2 enzyme-linked immunosorbent assay | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of mirincamycin (U24729A) against Plasmodium falciparum isolates from Gabon. |
| AID575077 | Antimicrobial activity against Streptococcus pneumoniae serotype 3 assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID285341 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20010734 in in Mueller-Hinton medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID557746 | Antimicrobial activity in Anaerococcus prevotii by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID548254 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID433007 | Antibacterial activity against Corynebacterium simulans isolated from patient with diabetic foot infection after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID574545 | Antimicrobial activity against community-associated methicillin-resistant Staphylococcus aureus USA300 | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID425091 | Antimicrobial activity against beta lactamase-positive Fusobacterium nucleatum isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID574554 | Decrease in PSMbeta1 levels in Staphylococcus aureus USA300 at subinhibitory concentration after 24 hrs by RP-HPLC/ESI-MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID369230 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae assessed as percent sensitive isolates by CLSI breakpoint method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID574951 | Antimicrobial activity against Streptococcus pneumoniae serotype 7F by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID405139 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate assessed as percent susceptible isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID572009 | Antibacterial activity against Fusobacterium mortiferum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID571174 | Antimicrobial activity against Clostridium difficile harboring other ribotypes by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Clostridium difficile infections in a Canadian tertiary care hospital before and during a regional epidemic associated with the BI/NAP1/027 strain. |
| AID522180 | Antimicrobial activity against Propionibacterium acnes under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID529872 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring pAT392 containing mph(B) gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID373748 | Antimicrobial activity against mupirocin-resistant methicillin-resistant Staphylococcus aureus by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. |
| AID557464 | Antimicrobial activity in Prevotella disiens by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID562400 | Antimicrobial activity against erythromycin-susceptible Streptococcus Group F clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID575149 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus VRS3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID206369 | In vitro antibacterial activity against the aerobic Staphylococcus faecalis (Strain UC no.694) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID322997 | Antibacterial activity against drug-resistant Propionibacterium granulosum NCTC-11865 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID557734 | Antimicrobial activity in Peptostreptococcus anaerobius by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID561237 | Antibacterial activity against methicillin-resistant Staphylococcus aureus by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID535253 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-1 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID540213 | Half life in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID520735 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring erm(B) and cfr gene by disk diffusion assay | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. |
| AID433006 | Antibacterial activity against Corynebacterium accolens isolated from patient with diabetic foot infection after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID531574 | Antibacterial activity against Aerococcus viridans obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID1241210 | Binding affinity to 5'-FAM-pre-miR-17 (unknown origin) after 4 hrs by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID565738 | Antimicrobial activity against erythromycin-susceptible Streptococcus pyogenes clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID433160 | Antibacterial activity against Clostridium clostridioforme isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID534463 | Antimicrobial activity against Bacteroides fragilis GAI 0558 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID573593 | Antibacterial activity against Fusobacterium necrophorum by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID574770 | Antimicrobial activity against Clostridium perfringens after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID206676 | In vitro antibacterial activity against the aerobic Staphylococcus mitis (Strain UC no.871) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID278877 | Inhibition of metabolic activity in primary human osteoblasts in presence of 10% FCS | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID342063 | Antimicrobial activity against nonepidemic Clostridium difficile J29 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID531519 | Antibacterial activity against Bacteroides thetaiotaomicron assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID535013 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID508424 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2686 harboring mutation in L4 ribosomal protein after 50 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID548795 | Antimicrobial activity against Oxacillin-susceptible coagulase-negative Staphylococcus assessed as percent resistant isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID278857 | Inhibition of metabolic activity in primary human osteoblasts assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID1698699 | Antibacterial activity against Peptostreptococcus anaerobius ATCC 27337 by CLSI method | 2020 | Bioorganic & medicinal chemistry, 11-15, Volume: 28, Issue:22 | Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors. |
| AID1879533 | Antibacterial activity against Atopobium vaginae BAA-55 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID323000 | Antibacterial activity against drug-resistant Propionibacterium acnes SW3CD after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID573799 | Antibacterial activity against Prevotella buccae assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID425112 | Antimicrobial activity against beta lactamase-positive Prevotella intermedia isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID50850 | Minimum inhibitory concentration against Clostridium difficile ATCC 9689 | 1989 | Journal of medicinal chemistry, May, Volume: 32, Issue:5 | Aromatic dienoyl tetramic acids. Novel antibacterial agents with activity against anaerobes and staphylococci. |
| AID522196 | Antimicrobial activity against Clostridium inoculum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID422651 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3665 after 26 passages with clarithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID531529 | Antibacterial activity against Bacteroides uniformis isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID574003 | Antibacterial activity against beta-lactamase producing Clostridium perfringens assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID508467 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2094 harboring erm(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID574953 | Antimicrobial activity against Streptococcus pneumoniae serotype 6C by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID129556 | In vivo antibacterial activity against Streptococcus pyogenes(UC 152) infected mice after sc administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID386623 | Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells at 100 uM by confocal microscopy | 2008 | Journal of medicinal chemistry, Oct-09, Volume: 51, Issue:19 | Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. |
| AID433002 | Antibacterial activity against Corynebacterium jeikeium isolated from patient with diabetic foot infection after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID508393 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 1077 after 29 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID522144 | Antimicrobial activity against Prevotella bergensis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID1698703 | Antibacterial activity against Fusobacterium nucleatum JCM8532 by CLSI method | 2020 | Bioorganic & medicinal chemistry, 11-15, Volume: 28, Issue:22 | Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors. |
| AID565761 | Antimicrobial activity against Staphylococcus aureus clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID522190 | Antimicrobial activity against Slackia exigua under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID433001 | Antibacterial activity against Corynebacterium aurimucosum isolated from patient with diabetic foot infection after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID571765 | Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-615-628MexB mutant gene | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID557960 | Antimicrobial activity in Clostridium perfringens by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID534342 | Antimicrobial activity against Burkholderia pseudomallei Bp58 harboring deleted bpeR::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID531570 | Antibacterial activity against Streptococcus sp. 'group G' obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID528729 | Antibacterial activity against multidrug-resistant Streptococcus pneumoniae clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID522183 | Antimicrobial activity against Atopobium parvulum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID369436 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID573823 | Antibacterial activity against beta-lactamase producing Clostridium paraputrificum by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID555295 | Antibacterial activity against Tmp-resistant Staphylococcus aureus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID533364 | Antimicrobial activity against Bacteroides thetaiotaomicron assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID572011 | Antibacterial activity against Prevotella bivia by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID522170 | Antimicrobial activity against Anaerococcus sp. under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID586054 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type 5 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID508387 | Antibacterial activity against macrolide-resistant Streptococcus pyogenes harboring mef(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID508471 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2011 harboring mef(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID425723 | Antimicrobial activity against Balamuthia mandrillaris ATCC 50209 infected in HBMEC assessed as inhibition of amoeba-induced cytopathogenicity at 10 ug/mL after 24 hrs by LDH release assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity. |
| AID522175 | Antimicrobial activity against Actinomyces israelii under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID1079941 | Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source] | |||
| AID508380 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae harboring mutation in L4 ribosomal protein after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID575143 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate NRS70 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID571799 | Antibacterial activity against Clostridium bifermentans by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID322792 | Antimicrobial activity against Bacteroides stercoris assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID206809 | In vitro antibacterial activity against the aerobic Staphylococcus pneumoniae I(Strain UC no.41) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID522168 | Antimicrobial activity against Anaerococcus octavius under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID574780 | Antimicrobial activity against Clostridium difficile assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID424617 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus AIS2006049 isolated from patients arm wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID625282 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID561242 | Antibacterial activity against methicillin-susceptible Staphylococcus epidermidis assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID571814 | Antibacterial activity against Clostridium sp. by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID425966 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3274 after 50 passages by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID558085 | Antimicrobial activity against Mycoplasma fermentans isolated from human by two fold serial dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101. |
| AID557964 | Antimicrobial activity in Clostridium difficile by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID572022 | Antibacterial activity against Prevotella oris by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID165058 | In vitro antibacterial activity against the aerobic Pseudomonas aeruginosa (Strain UC no.95) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID535255 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-3 expressing SCCmec type 4 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID565733 | Antimicrobial activity against Streptococcus Group G clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID128554 | Bioactivity in blood, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 360 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID531555 | Antibacterial activity against coagulase-negative Staphylococcus haemolyticus obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID1079943 | Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source] | |||
| AID425076 | Antimicrobial activity against beta lactamase-positive Bacteroides thetaiotaomicron isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID520956 | Antimicrobial activity against Corynebacterium amycolatum isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID528726 | Antibacterial activity against Streptococcus mitis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID511432 | Antimicrobial activity against Clostridium perfringens LFM1 assessed as resistance breakpoint by DIN-standardized microdilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Resistance to linezolid in a porcine Clostridium perfringens strain carrying a mutation in the rplD gene encoding the ribosomal protein L4. |
| AID718414 | Antibacterial activity against log-phase vancomycin-sensitive Enterococcus faecalis ATCC 19433 assessed as growth inhibition after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Dec-15, Volume: 20, Issue:24 | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. |
| AID559488 | Antibacterial activity against Peptostreptococcus sp. by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID516159 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates by CLSi method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID574522 | Antimicrobial activity against Prevotella buccae after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID519997 | Antimicrobial activity against Streptococcus pneumoniae ribosomal mutant | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID533135 | Antimicrobial activity against Bacteroides ovatus by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID585165 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA C2612A mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID573797 | Antibacterial activity against Prevotella intermedia assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID369446 | Antimicrobial activity against Streptococcus group A after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID574993 | Antimicrobial activity against Bifidobacterium sp. after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID433183 | Antibacterial activity against Corynebacterium jeikeium isolated from patient with diabetic foot infection assessed as percent resistant isolates after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID322776 | Antimicrobial activity against Bacteroides thetaiotaomicron isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID425080 | Antimicrobial activity against beta lactamase-positive Prevotella bivia isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID534479 | Antimicrobial activity against Prevotella corporis GAI 91000 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID522158 | Antimicrobial activity against Veillonella spp. under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID50729 | In vitro antibacterial activity against the anaerobic Clostridium cadaveris (Strain UC no.6510) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID516167 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as resistant isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID522184 | Antimicrobial activity against Colinsella aerofaciens under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID433153 | Antibacterial activity against Parabacteroides merdae isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID721791 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as growth inhibition after 24 hrs by CLSI broth microdilution method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. |
| AID531552 | Antibacterial activity against methicillin resistant Staphylococcus aureus obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID422673 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3009 after 18 passages with levofloxacin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID574955 | Antimicrobial activity against multiple drug resistant Streptococcus pneumoniae serotype 19F by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID529868 | Antimicrobial activity against Escherichia coli AG100A harboring pAT392 containing rdmC-like gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID531521 | Antibacterial activity against Bacteroides stercoris isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID572014 | Antibacterial activity against Prevotella P denticola by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID322782 | Antimicrobial activity against Bacteroides merdae isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID433187 | Antibacterial activity against Corynebacterium accolens isolated from patient with diabetic foot infection assessed as percent resistant isolates after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID535033 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-118 expressing SCCmec type 1 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID534453 | Antimicrobial activity against Lactobacillus acidophilus JCM 1132 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID541176 | Antimicrobial activity against multidrug resistant Streptococcus pneumoniae serotype 19F S43 carring erm(B),mef(E) and tet(M) gene | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | New composite genetic element of the Tn916 family with dual macrolide resistance genes in a Streptococcus pneumoniae isolate belonging to clonal complex 271. |
| AID573836 | Antibacterial activity against beta-lactamase producing Clostridium septicum assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID1870156 | Antibacterial activity against wild type Staphylococcus aureus 4515/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID522198 | Antimicrobial activity against Clostridium aldenense under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID545051 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ274 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID574490 | Antimicrobial activity against Bacteroides vulgatus after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID433012 | Antibacterial activity against Staphylococcus haemolyticus isolated from patient with diabetic foot infection after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID562367 | Antimicrobial activity against Streptococcus Group F clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID285157 | Antimicrobial susceptibility of tetracycline-resistant Streptococcus pneumoniae from respiratory tract disease patient assessed as percent susceptible isolates | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland. |
| AID533388 | Antimicrobial activity against Clostridium difficile assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID283659 | Antimicrobial activity against Haemophilus influenzae CDS01 mutant with acrB insertional inactivation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number. |
| AID72255 | In vitro antibacterial activity against the anaerobic Fusobacterium nucleatum (Strain UC no.6516) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID283552 | Antimicrobial activity against Streptococcus pneumoniae PC13 isolate with erm(B) mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID529873 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring pAT392 containing mph(B) and rdmC-like genes by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID531567 | Antibacterial activity against Streptococcus agalactiae obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID571789 | Antibacterial activity against Clostridium bolteae by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID557432 | Antimicrobial activity in Bacteroides stercoris by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID278505 | Antibacterial activity against Pneumococcus CDC020 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID528975 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID522188 | Antimicrobial activity against Eubacterium saburreum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID574520 | Antimicrobial activity against Prevotella bivia after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID535257 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-5 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID571808 | Antibacterial activity against Clostridium scindens by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID50990 | In vitro activity against Clostridium perfringens (104AT13124) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID1870137 | Antibacterial activity against wild type methicillin resistant Staphylococcus aureus 4561/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID571817 | Antibacterial activity against Bifidobacterium bifidum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID278504 | Antibacterial activity against Pneumococcus CDC018 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID72265 | In vitro antibacterial activity against the anaerobic Fusobacterium varium(Strain UC no.6052) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID522207 | Antimicrobial activity against Clostridium difficile under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID533863 | Antibacterial activity against toxin-positive Clostridium difficile clinical isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of OPT-80 tested against clinical isolates of toxin-producing Clostridium difficile. |
| AID574738 | Antimicrobial activity against Fusobacterium mortiferum after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID1879561 | Antibacterial activity against Gardnerella vaginalis ATCC 14018 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID1079938 | Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source] | |||
| AID574997 | Antimicrobial activity against Bifidobacterium sp. assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID547538 | Antimicrobial activity against invasive Streptococcus anginosus obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of 5% | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID575146 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate NRS123 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID322779 | Antimicrobial activity against Bacteroides caccae isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID433170 | Antibacterial activity against Peptostreptococcus micros isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID571811 | Antibacterial activity against Clostridium sporogenes by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID562584 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus agalactiae clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID547533 | Antimicrobial activity against Streptococcus intermedius obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on brain heart infusion agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID575079 | Antimicrobial activity against Streptococcus pneumoniae serotype 7F assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID425115 | Antimicrobial activity against Clostridium perfringens isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID509632 | Antimicrobial activity against Staphylococcus aureus 25 transformant carrying plasmid pKKS25 and expressing erm(T), dfrKtet(L), tet(K), tet(M), mecA and blaZ genes by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID559487 | Antibacterial activity against Fusobacterium sp. by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID572001 | Antibacterial activity against Parabacteroides distasonis by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID559491 | Antibacterial activity against Bacteroides fragilis assessed as percent susceptible isolates by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID522191 | Antimicrobial activity against Solobacterium moorei under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID508370 | Antibacterial activity against Streptococcus pneumoniae harboring mef(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID1870141 | Antibacterial activity against wild type Staphylococcus aureus 4463/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID694208 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 by CLSI broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 22, Issue:22 | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. |
| AID548526 | Antimicrobial activity against Oxacillin-resistant Staphylococcus aureus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID425652 | Total body clearance in human | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15 | Physicochemical determinants of human renal clearance. |
| AID534337 | Antimicrobial activity against Burkholderia pseudomallei Bp216 harboring mini-Tn7T after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID535021 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-18 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID129553 | In vivo antibacterial activity against Streptococcus pneumoniae III(UC 3213) infected mice after oral administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID573802 | Antibacterial activity against Prevotella melaninogenica assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID555293 | Antibacterial activity against methicillin-resistant Staphylococcus aureus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID574052 | Antibacterial activity against beta-lactamase producing Finegoldia magna assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID522204 | Antimicrobial activity against Clostridium butyricum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID495943 | Antimicrobial activity against erythromycin, lincomycin, clindamycin resistant Staphylococcus haemolyticus isolate 65OL harboring ermC vgaALC gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID547539 | Antimicrobial activity against invasive Streptococcus anginosus obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on brain heart infusion agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID508371 | Antibacterial activity against Streptococcus pneumoniae harboring erm(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID433202 | Antibacterial activity against Bacteroides thetaiotaomicron isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID533385 | Antimicrobial activity against Clostridium difficile by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID562606 | Antimicrobial activity against Streptococcus pneumoniae clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID522200 | Antimicrobial activity against Clostridium citroniae under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID670959 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 24 hrs by microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. |
| AID717271 | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 by CLSI protocol based broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. |
| AID278664 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 595 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID520290 | Antimicrobial activity against Staphylococcus aureus 2547 small colony variants | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID534451 | Antimicrobial activity against Propionibacterium acnes ATCC 11828 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID533417 | Antimicrobial activity against Micromonas micros by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID528977 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID41561 | In vitro activity against Bacteroides vulgatus(792) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID433158 | Antibacterial activity against Clostridium aminovalericum isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID1909745 | Invivo antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 infected Balb/c mouse model assessed as reduction in bacterial infection in skin wounds at 25 mg/kg ip administered 2 days post infection twice daily and measured aft | 2022 | Journal of medicinal chemistry, 05-12, Volume: 65, Issue:9 | Mechanistic Studies and |
| AID562365 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus Group F clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID575148 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus VRS2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID425081 | Antimicrobial activity against beta lactamase-positive Prevotella disiens isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID562580 | Antimicrobial activity against Streptococcus Group C clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID207635 | In vitro antibacterial activity for minimum inhibition concentration (MIC) required to inhibit growth of Staphylococcus aureus | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID554556 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC1082 preincubated with 2 ug/ml erythromycin for 20 to 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID41430 | In vitro antibacterial activity against the anaerobic Bacteroides thetaiotaomicron (Strain UC no.6512) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID522208 | Antimicrobial activity against Clostridium glycolicum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID561514 | Antibacterial activity against Enterococcus faecalis by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID1428626 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 by broth microdilution method | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. |
| AID508378 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae harboring mef(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID524900 | Antibacterial activity against constitutive macrolide-lincosamide-streptogramin B resistant erm(B) and mef(E)-positive Streptococcus pneumoniae by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. |
| AID508473 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 237 harboring mutation in L4 ribosomal protein after 20 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID535027 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-27 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID520957 | Antimicrobial activity against Corynebacterium jeikeium isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID574502 | Antimicrobial activity against Bacteroides caccae assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID531513 | Antibacterial activity against Bacteroides spp. assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID596084 | Antiparasitic activity against clindamycin-resistant Toxoplasma gondii 4 infected in HFF assessed as reduction of ycf24/UPRT genes copy number ratio at 1 uM treated for 48 hrs after 6 hrs infection followed by reinoculated into fresh HFF monolayers measur | 2011 | Journal of medicinal chemistry, Apr-28, Volume: 54, Issue:8 | Chemistry and biology of macrolide antiparasitic agents. |
| AID422681 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3009 after 50 passages by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID508465 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2094 harboring erm(A) gene after 34 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID422682 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1635 after 14 passages with clindamycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID562394 | Antimicrobial activity against oxacillin-susceptible Staphylococcus epidermidis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID571823 | Antibacterial activity against Catenibacterium mitsuokai by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID574742 | Antimicrobial activity against Peptostreptococcus micros after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID522134 | Antimicrobial activity against Bacteroides caccae under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID433361 | Antibacterial activity against Clostridium clostridioforme isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID522215 | Antimicrobial activity against Clostridium tertium under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID586044 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type 4 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID522192 | Antimicrobial activity against Lactobacillus casei under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID160381 | In vitro activity against Propionibacterium acnes (132) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID425101 | Antimicrobial activity against Clostridium perfringens isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID571816 | Antibacterial activity against Bifidobacterium adolescentis by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID522171 | Antimicrobial activity against Gemella morbillorum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID571805 | Antibacterial activity against Clostridium leptum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID50846 | In vitro antibacterial activity against the anaerobic Clostridium difficile (Strain UC no.6860) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID573835 | Antibacterial activity against beta-lactamase producing Clostridium paraputrificum assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID433371 | Antibacterial activity against Peptostreptococcus micros isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID571821 | Antibacterial activity against Bifidobacterium longum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1079934 | Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source] | |||
| AID522174 | Antimicrobial activity against Peptoniphilus lacrimalis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID533397 | Antimicrobial activity against Clostridium paraputrificum by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID531523 | Antibacterial activity against Bacteroides eggerthii isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID72253 | In vitro activity against Fusobacterium nucleatum (ATCC 25586) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID528849 | Antimicrobial activity against methicillin-susceptible Staphylococcus epidermidis isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID531572 | Antibacterial activity against Streptococcus mitis obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID545055 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate CC023 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID425980 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1635 after 14 passages with azithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID533389 | Antimicrobial activity against Clostridium perfringens by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID433005 | Antibacterial activity against Corynebacterium striatum isolated from patient with diabetic foot infection after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID369444 | Antibacterial activity against penicillin-intermediate Streptococcus pneumoniae after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID433355 | Antibacterial activity against Porphyromonas asaccharolyticus isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID433016 | Antibacterial activity against Streptococcus pyogenes isolated from patient with diabetic foot infection after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID583892 | Antibacterial activity against vancomycin-heteroresistant Staphylococcus aureus isolate 443 by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID497971 | Drug level in bone/joint infection patient serum assessed as median concentration at 2400 mg, iv after 3 to 14 days | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Continuous clindamycin infusion, an innovative approach to treating bone and joint infections. |
| AID522213 | Antimicrobial activity against Clostridium subterminale under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID557972 | Antimicrobial activity in Clostridium tertium by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID283661 | Antimicrobial activity against Haemophilus influenzae CDS40 mutant with acrB insertional inactivation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number. |
| AID574950 | Antimicrobial activity against Streptococcus pneumoniae serotype 35B by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID557456 | Antimicrobial activity in Prevotella nigrescens by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID573394 | Antibacterial activity against Bacteroides fragilis by by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID534679 | Antimicrobial activity against Desulfovibrio piger DSM 749 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID535634 | Antimicrobial activity against Group B streptococcus serotype VI R6 harboring F395L, V405A, R433H, H438Y, A374V and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID574989 | Antimicrobial activity against Bifidobacterium adolescentis assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID278481 | Antibacterial activity against Pneumococcus DAW12 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID519994 | Antimicrobial activity against Streptococcus pneumoniae harboring erm(B) gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID534676 | Antimicrobial activity against Fusobacterium necrophorum ATCC 25286 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID535646 | Antimicrobial activity against Group B Streptococcus serotype III NEM 316 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1870155 | Antibacterial activity against wild type Staphylococcus aureus 4502/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID535024 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-23 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID278856 | Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID522172 | Antimicrobial activity against Gemella sanguinis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID571829 | Antibacterial activity against Propionibacterium propionicus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID581664 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient infected in human THP-1 cells assessed as log reduction of intracellular CFU level per mg of protein after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID519067 | Antibacterial activity against multidrug resistant Streptococcus pneumoniae ATCC 49619 assessed as resistant strains by CLSI microdilution susceptibility testing method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Activity of the Diaminopyrimidine AR-709 against recently collected multidrug-resistant isolates of invasive Streptococcus pneumoniae from North America. |
| AID372519 | Antimalarial activity as 3rd generation parasitaemia against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 96hrs at 25 nM dosed 0-36 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID1079944 | Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source] | |||
| AID562406 | Antimicrobial activity against penicillin-intermediate Streptococcus pneumoniae clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID285160 | Antimicrobial activity against non replicating persistence Mycobacterium tuberculosis H37Rv in aerobic condition assessed as bacterial density after 7 days | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. |
| AID396026 | Antibacterial activity against drug-resistant Enterobacter cloacae EcDC64 isolate expressing AcrAB-TolC efflux pump by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID557742 | Antimicrobial activity in Anaerococcus tetradius by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID323009 | Antibacterial activity against drug-resistant Propionibacterium acnes FG7E after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID575099 | Antimicrobial activity against Streptococcus pneumoniae serotype 15A assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID768036 | Antibacterial activity against Bacillus subtilis 168 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID372526 | Antimalarial activity as 3rd generation parasitaemia after 96 hrs against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes at 25 nM 36-48 hrs post invasion | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID1459986 | In vivo antiparasitic activity against Babesia sp. assessed as fever clearance time | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Comprehensive review on various strategies for antimalarial drug discovery. |
| AID524827 | Antibacterial activity against erythromycin susceptible Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID548738 | Antimicrobial activity against Oxacillin-resistant Staphylococcus aureus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID561245 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID577444 | Antimicrobial activity against Staphylococcus aureus USA300 isolate harboring pSK41 plasmid expressing ermC gene assessed resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States. |
| AID561738 | Antibacterial activity against Beta-hemolytic Streptococcus group A assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID565756 | Antimicrobial activity against oxacillin-resistant Staphylococcus epidermidis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID574973 | Antimicrobial activity against Actinomyces israelii assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID554553 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC1082 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID534450 | Antimicrobial activity against Eggerthella lenta ATCC 25559 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID508366 | Antibacterial activity against penicillin-intermediate Streptococcus pneumoniae after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID278861 | Inhibition of metabolic activity in HeLa cells assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID433156 | Antibacterial activity against Prevotella bivia isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID425086 | Antimicrobial activity against beta lactamase-positive Prevotella corporis isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID206899 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6689) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID41424 | In vitro activity against Bacteroides thetaiotaomicron (SFM2975-2) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID574530 | Antimicrobial activity against Prevotella bivia assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID555743 | Antibacterial activity against methicillin-resistant, vancomycin-intermediate coagulase-negative Staphylococcus epidermidis 225 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID283556 | Antimicrobial activity against Streptococcus pneumoniae R6 with L4 mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID534448 | Antimicrobial activity against Bifidobacterium longum subsp. longum ATCC 15707 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID522165 | Antimicrobial activity against Peptostreptococcus stomatis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID534673 | Antimicrobial activity against Porphyromonas gingivalis ATCC 33277 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID1079932 | Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source] | |||
| AID572004 | Antibacterial activity against Bacteroides ovatus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID529866 | Antimicrobial activity against Streptococcus uberis UCN60 expressing mph(B) and rdmC-like genes by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID495942 | Antimicrobial activity against erythromycin resistant Staphylococcus epidermidis isolate 129OV harboring msrA gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID561258 | Antibacterial activity against Streptococcus agalactiae assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID404952 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus sp. assessed as percent susceptible isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID574981 | Antimicrobial activity against Actinomyces naeslundii after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID217865 | In vitro activity against Veillonella parvula (ATCC 10790) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID528839 | Antimicrobial activity against vancomycin-resistant Enterococcus sp. isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID557952 | Antimicrobial activity in Actinomyces by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID572013 | Antibacterial activity against Prevotella corporis by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID508372 | Antibacterial activity against Streptococcus pneumoniae harboring erm(B) and mef(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID572021 | Antibacterial activity against Prevotella oralis by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID575007 | Antimicrobial activity against Eubacterium sp. assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID528725 | Antibacterial activity against Streptococcus intermedius clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID495939 | Antimicrobial activity against lincomycin resistant Staphylococcus haemolyticus isolate 123PL harboring lnuA gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID508433 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 7127 harboring S20N mutation in L4 ribosomal protein and A105V mutation in L22 ribosomal protein after 43 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID739305 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus 8325-4 assessed as growth inhibition by CLSI broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. |
| AID531794 | Antibacterial activity against SCCmec type 2 genotype-positive and methicillin-resistant Staphylococcus aureus by CLSI method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. |
| AID571172 | Antimicrobial activity against Clostridium difficile harboring ribotype 027 by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Clostridium difficile infections in a Canadian tertiary care hospital before and during a regional epidemic associated with the BI/NAP1/027 strain. |
| AID529875 | Antimicrobial activity against Enterococcus faecalis JH2-2 harboring pAT392 containing mph(B) gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID531578 | Antibacterial activity against Lactococcus lactis obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID572023 | Antibacterial activity against Sutterella wadsworthensis by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID522140 | Antimicrobial activity against Prevotella bivia under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID573784 | Antibacterial activity against Prevotella bivia by by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID278501 | Antibacterial activity against Pneumococcus DAW86 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID285344 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20040332 in Mueller-Hinton medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID533404 | Antimicrobial activity against Clostridium subterminale assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID567568 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring pBS-01multiple resistance gene cfr and phenolic resistance gene fexA obtained from swine feces | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. |
| AID508451 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 2132 after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID528848 | Antimicrobial activity against methicillin-resistant Staphylococcus epidermidis assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID41251 | In vitro activity against Bacteroides fragilis (SFM2906A) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID422657 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3665 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID519138 | Antimicrobial activity against community-acquired methicillin resistant Staphylococcus aureus expressing PVL and mec type IV gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. |
| AID561233 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID369437 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID534472 | Antimicrobial activity against Bacteroides uniformis ATCC 8492 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID557452 | Antimicrobial activity in Prevotella intermedia by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID205750 | In vitro antibacterial activity against the aerobic Staphylococcus epidermidis (Strain UC no.719) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID541031 | Induction of apoptosis in bovine BL3 cells assessed as necrotic after 24 hrs by annexin V/propidium iodide staining-based FACS analysis | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Theileria apicoplast as a target for chemotherapy. |
| AID372520 | Antimalarial activity as 3rd generation parasitaemia against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 96hrs at 25 nM dosed 0-48 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID297186 | Antibacterial activity against multidrug resistant Staphylococcus aureus 49589 | 2007 | Journal of medicinal chemistry, Aug-23, Volume: 50, Issue:17 | Structure-activity relationships of phenyl-furanyl-rhodanines as inhibitors of RNA polymerase with antibacterial activity on biofilms. |
| AID571796 | Antibacterial activity against Clostridium subterminale by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID508391 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 1077 after 43 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID575103 | Antimicrobial activity against Streptococcus pneumoniae serotype 23A assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID533408 | Antimicrobial activity against Clostridium tertium assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID574553 | Decrease in PSMbeta1 levels in Staphylococcus aureus Sanger 252 at subinhibitory concentrations after 24 hrs by RP-HPLC/ESI- MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID404901 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB41 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID585877 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 4 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID278859 | Inhibition of metabolic activity in MG63 cells assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID323008 | Antibacterial activity against drug-resistant Propionibacterium acnes GE46EB after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID768025 | Inhibition of protein synthesis in Escherichia coli S30 extracts after 90 mins by coupled transcription/translation assay | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID323012 | Antibacterial activity against drug-resistant Propionibacterium acnes SW101CDA after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID554555 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC1028 preincubated with 2 ug/ml erythromycin for 20 to 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID557956 | Antimicrobial activity in Eggerthella lenta by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID522194 | Antimicrobial activity against Clostridium perfringens under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID562391 | Antimicrobial activity against oxacillin-susceptible Staphylococcus haemolyticus clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID535028 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-51 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID372522 | Antimalarial activity as3rd generation parasitaemia against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 96 hrs at 25 nM dosed 12-36 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID90977 | Percentage growth inhibition of Toxoplasma gondii at concentration of 2 ug/mL using an human myelomonocytic cell line THP-1 | 2000 | Bioorganic & medicinal chemistry letters, May-01, Volume: 10, Issue:9 | Quinonic derivatives active against a virulent strain of Toxoplasma gondii. Synthesis of 2-methylfuro[2,3-g]- and [3,2-g]isoquinolinetriones. |
| AID425096 | Antimicrobial activity against Micromonas micros isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID519139 | Antimicrobial activity against community-acquired methicillin resistant Staphylococcus aureus expressing PVL gene and mec type IV gene assessed as susceptible strains by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. |
| AID531512 | Antibacterial activity against Bacteroides eggerthii assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID625292 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) combined score | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID585170 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA U2504G mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID425116 | Antimicrobial activity against Clostridium difficile isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID533424 | Antimicrobial activity against Anaerococcus prevotii assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID562410 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus Group G clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID529871 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring pAT392 containing rdmC-like gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID520965 | Antimicrobial activity against Listeria monocytogenes isolates by CLSI M45-A protocol based microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Activity of Tigecycline against Coryneform Bacteria of Clinical Interest and Listeria monocytogenes. |
| AID323659 | Antibacterial activity against Peptostreptococcus anaerobius | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antimicrobial susceptibilities of Peptostreptococcus anaerobius and the newly described Peptostreptococcus stomatis isolated from various human sources. |
| AID342098 | Increase in toxin level in epidemic Clostridium difficile BI9 infected CF1 mouse at 1.4 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID423266 | Antibacterial activity against azithromycin-resistant 0.01 MOI Chlamydia psittaci 6BC BCRBAZ2 harboring A2058C mutation in bacterial 23S rRNA gene infected in mouse L2 cells treated 2 hrs after infection measured on day 7 by plaque assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2. |
| AID565728 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus Group F clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID574954 | Antimicrobial activity against multiple drug resistant Streptococcus pneumoniae serotype 19A by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID571926 | Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-N623S-Q624S mutant gene | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID574971 | Antimicrobial activity against Actinomyces israelii assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID571834 | Antibacterial activity against Ruminococcus luti by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID533376 | Antimicrobial activity against Bacteroides eggerthii assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID586041 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 5 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID396033 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pBGS18 plasmid by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID495934 | Antimicrobial activity against erythromycin, lincomycin, clindamycin resistant Staphylococcus haemolyticus isolate 134PL harboring ermC gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID575944 | Antimicrobial activity against erythromycin-resistant Streptococcus pneumoniae by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates. |
| AID528842 | Antimicrobial activity against penicillin-resistant Streptococcus pneumoniae isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID520732 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring plasmid LI50 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. |
| AID565079 | Antibacterial activity against community-acquired methicillin-resistant Staphylococcus aureus 147 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Pharmacodynamic profile of tigecycline against methicillin-resistant Staphylococcus aureus in an experimental pneumonia model. |
| AID323017 | Antibacterial activity against drug-resistant Propionibacterium acnes SW3CD after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID433166 | Antibacterial activity against Anaerococcus tetradius isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID548524 | Antimicrobial activity against Oxacillin-resistant Staphylococcus aureus assessed as percent resistant isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID531517 | Antibacterial activity against Bacteroides vulgatus assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID533401 | Antimicrobial activity against Clostridium subterminale by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID574547 | Increase in PSMalpha levels in Staphylococcus aureus USA300 at subinhibitory concentrations after 24 hrs by RP-HPLC/ESI- MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID574728 | Antimicrobial activity against Prevotella oralis assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID548533 | Antimicrobial activity against Beta-hemolytic Streptococcus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID534675 | Antimicrobial activity against Fusobacterium varium ATCC 8501 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID554552 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC1028 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID596083 | Antiparasitic activity against green fluorescent protein expressing hwgprt deficient Toxoplasma gondii RH infected in HFF assessed as reduction of ycf24/UPRT genes copy number ratio at 1 uM treated for 48 hrs after 6 hrs infection followed by reinoculated | 2011 | Journal of medicinal chemistry, Apr-28, Volume: 54, Issue:8 | Chemistry and biology of macrolide antiparasitic agents. |
| AID433018 | Antibacterial activity against Bacteroides caccae isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID497972 | Drug level in bone/joint infection patient serum assessed as median concentration at 2400 mg, iv after 8 to 28 days | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Continuous clindamycin infusion, an innovative approach to treating bone and joint infections. |
| AID278592 | Inhibition of fatty acid biosynthesis in Plasmodium falciparum FCK2 as [1,2-14C]acetate uptake during first asexual cycle at 10 uM after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID128557 | Bioactivity in blood, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 90 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID278576 | Inhibition of Plasmodium falciparum FCK2 growth as [3H]hypoxanthine uptake after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID516160 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as susceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID571988 | Antibacterial activity against Ruminococcus lactaris by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID535030 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-73 expressing SCCmec type 4d element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID574492 | Antimicrobial activity against Bacteroides ovatus after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID433181 | Antibacterial activity against Corynebacterium amycolatum isolated from patient with diabetic foot infection assessed as percent resistant isolates after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID422687 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3413 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID531524 | Antibacterial activity against Bacteroides spp. isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID554549 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC879-2 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID522145 | Antimicrobial activity against Prevotella corporis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID583887 | Antibacterial activity against community-associated methicillin-resistant Staphylococcus aureus isolate 145 by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID425978 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 24 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID1079946 | Presence of at least one case with successful reintroduction. [column 'REINT' in source] | |||
| AID433011 | Antibacterial activity against Staphylococcus epidermidis isolated from patient with diabetic foot infection after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID508388 | Antibacterial activity against macrolide-resistant Streptococcus pyogenes harboring erm(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID558000 | Antimicrobial activity in Clostridium clostridioforme by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID561341 | Antibacterial activity against Methicillin-resistant Staphylococcus aureus by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID535641 | Antimicrobial activity against Group B streptococcus serotype V C1 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID522156 | Antimicrobial activity against Fusobacterium mortiferum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID425077 | Antimicrobial activity against beta lactamase-positive Bacteroides ovatus isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID558185 | Antimicrobial activity against Mycobacterium abscessus isolate MC1028 at day 7 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID533635 | Antimicrobial activity against Propionibacterium sp. by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID575948 | Antimicrobial activity against erythromycin-resistant Streptococcus pneumoniae assessed as resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates. |
| AID718413 | Antibacterial activity against log-phase vancomycin-resistant Enterococcus faecalis ATCC 51575 assessed as growth inhibition after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Dec-15, Volume: 20, Issue:24 | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. |
| AID555737 | Antibacterial activity against methicillin-resistant and vancomycin-resistant Staphylococcus aureus VRS1 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID404937 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus sp. by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID571826 | Antibacterial activity against Coriobacteriumecies by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1079936 | Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source] | |||
| AID561246 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID571806 | Antibacterial activity against Clostridium orbiscindens by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID41253 | In vitro activity against Bacteroides fragilis (SFM2975-7) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID508397 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 1077 after 49 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID422688 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3413 after 50 passages by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID433184 | Antibacterial activity against Corynebacterium minutissimum isolated from patient with diabetic foot infection assessed as percent resistant isolates after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID574754 | Antimicrobial activity against Anaerococcus prevotii assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID422656 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3665 after 50 passages by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID574762 | Antimicrobial activity against Peptoniphilus asaccharolyticus assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID531569 | Antibacterial activity against Streptococcus sp. 'group C' obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID573397 | Antibacterial activity against beta-lactamase producing Bacteroides thetaiotaomicron by by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID433152 | Antibacterial activity against Parabacteroides distasonis isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID1329004 | Antibacterial activity against Clostridium difficile infected in hamster model assessed as median survival time | 2016 | Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24 | Discovery, pharmacology, and clinical profile of omadacycline, a novel aminomethylcycline antibiotic. |
| AID522159 | Antimicrobial activity against Anaerococcus prevotii under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID327749 | Antibacterial activity against Enterococcus faecalis by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Novel antibacterial azetidine lincosamides. |
| AID372473 | Antimalarial activity as arrested schizont maturation in chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 48 hrs at 25 nM dosed 96 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID561265 | Antibacterial activity against Enterococcus faecium by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID41113 | In vitro activity against Bacteroides disiens (ATCC 29426) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID322995 | Antibacterial activity against drug-resistant Propionibacterium acnes EG7NS after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID425110 | Antimicrobial activity against beta lactamase-positive Bacteroides fragilis isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID581665 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient in cation-adjusted MH 2 broth assessed as log reduction of extracellular CFU level at up to 10'5 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID1079940 | Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source] | |||
| AID1879573 | Antibacterial activity against Prevotella disiens MMX 3457 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID278494 | Antibacterial activity against Pneumococcus DAW62 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID322777 | Antimicrobial activity against Bacteroides uniformis isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID516163 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as resistant isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID425097 | Antimicrobial activity against Peptostreptococcus anaerobius isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID372521 | Antimalarial activity as 3rd generation parasitaemia against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 96hrs at 25 nM dosed 12-24 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID571992 | Antibacterial activity against Anaerococcus prevotii by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID528978 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID571925 | Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-G616N mutant gene | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID574534 | Antimicrobial activity against Prevotella buccae assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID559489 | Antibacterial activity against Prevotella sp. by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID1870153 | Antibacterial activity against wild type Staphylococcus aureus 4461/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID322778 | Antimicrobial activity against Bacteroides vulgatus isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID522205 | Antimicrobial activity against Clostridium cadaveris under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID535010 | Antimicrobial activity against daptomycin-nonsusceptible Staphylococcus aureus assessed as susceptible isolates by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID372495 | Antimalarial activity as abnormal apicoplast morphology in chloroquine-sensitive ACP1-GFP-labeled Plasmodium falciparum 3D7 after 48 hrs at 2xIC50 dosed 96 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID530121 | Antimicrobial activity against hospital acquired methicillin-resistant Staphylococcus aureus 152 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. |
| AID1230064 | Antibacterial activity against methicillin-resistant Staphylococcus aureus GRE2272 assessed as inhibition of bacterial growth | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. |
| AID528707 | Antibacterial activity against Streptococcus pyogenes group A clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID327746 | Antibacterial activity against Staphylococcus aureus by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Novel antibacterial azetidine lincosamides. |
| AID425982 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1635 after 14 passages by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID557710 | Antimicrobial activity in Fusobacterium nucleatum by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID573785 | Antibacterial activity against Prevotella intermedia by by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID571763 | Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-F628F mutant gene | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID555294 | Antibacterial activity against Tmp-susceptible Staphylococcus aureus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID573800 | Antibacterial activity against Prevotella bivia assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID508386 | Antibacterial activity against macrolide-resistant Streptococcus pyogenes harboring erm(B) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID554534 | Antimicrobial activity against Mycobacterium abscessus isolate MC879 on day 4 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID534475 | Antimicrobial activity against Campylobacter gracilis JCM 8538 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID342086 | Effect on growth of epidemic Clostridium difficile BI9 in CF1 mouse assessed as increase in bacterial density in cecal content at 2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID522182 | Antimicrobial activity against Eggerthella lenta under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID583890 | Antibacterial activity against hospital-associated methicillin-resistant Staphylococcus aureus isolate 412 by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID532675 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID1241211 | Binding affinity to 5'-FAM-pre-miR-373 (unknown origin) after 4 hrs by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID557424 | Antimicrobial activity in Bacteroides distasonis by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID548472 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID433000 | Antibacterial activity against Corynebacterium amycolatum isolated from patient with diabetic foot infection after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID535006 | Bactericidal activity against vancomycin-intermediate Staphylococcus aureus assessed as antibiotic concentration that reduced the number of viable cells by =>99.9% by colony count method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID562370 | Antimicrobial activity against Streptococcus Group G clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID424425 | Antibacterial activity against Enterococcus faecalis AIS2007003 isolated from patients rectum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID571173 | Antimicrobial activity against Clostridium difficile harboring ribotype 001 by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Clostridium difficile infections in a Canadian tertiary care hospital before and during a regional epidemic associated with the BI/NAP1/027 strain. |
| AID573822 | Antibacterial activity against beta-lactamase producing Clostridium perfringens by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID433019 | Antibacterial activity against Bacteroides ovatus isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID522133 | Antimicrobial activity against Bacteroides fragilis spp. under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID555296 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus aureus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID129552 | In vivo antibacterial activity against Streptococcus pneumoniae I(UC 41) infected mice after oral administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID422660 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1077 after 49 passages by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID533631 | Antimicrobial activity against Propionibacterium acnes by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID278860 | Antiproliferative effect against HeLa cells after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID573592 | Antibacterial activity against Fusobacterium mortiferum by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID1230066 | Antibacterial activity against methicillin-resistant Staphylococcus aureus GRE2691 assessed as inhibition of bacterial growth | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and antimicrobial activity of chloramphenicol-polyamine conjugates. |
| AID533372 | Antimicrobial activity against Bacteroides vulgatus assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID542389 | Antimicrobial activity against Staphylococcus aureus RN4220 transformed with Staphylococcus aureus ST9 plasmid pSCFS3 carrying cfr and fexA genes | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID423268 | Antibacterial activity against azithromycin-resistant 0.01 MOI Chlamydia psittaci 6BC BCRBAZ1 harboring A2059G mutation in bacterial 23S rRNA gene infected in mouse L2 cells treated 2 hrs after infection measured on day 7 by plaque assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2. |
| AID1879551 | Antibacterial activity against Bacteroides uniformis MMX 1277 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID574032 | Antibacterial activity against beta-lactamase producing Micromonas micros by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID433194 | Antibacterial activity against Staphylococcus lugdunensis isolated from patient with diabetic foot infection assessed as percent resistant isolates after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID572019 | Antibacterial activity against Prevotella loescheii by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID522177 | Antimicrobial activity against Actinomyces neuii subsp. anitratus under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID72254 | In vitro antibacterial activity against the anaerobic Fusobacterium nucleatum (Strain UC no.6324) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID41409 | In vitro activity against Bacteroides melaninogenicus (ATCC 25845). | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID278482 | Antibacterial activity against Pneumococcus DAW13 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID531579 | Antibacterial activity against Micrococcus spp. obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID571999 | Antibacterial activity against Streptococcus constellatus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID561260 | Antibacterial activity against Streptococcus agalactiae assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID548525 | Antimicrobial activity against Oxacillin-susceptible Staphylococcus aureus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID545052 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ363 from patient secretion by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID424331 | Antimicrobial activity against Dialister propionicifaciens assessed as susceptibility breakpoint by CA-SFM method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID562586 | Antimicrobial activity against Streptococcus agalactiae clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID425113 | Antimicrobial activity against beta lactamase-positive Finegoldia magna isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID586046 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type 2 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID1879556 | Antibacterial activity against Bifidobacterium longum ATCC 15707 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID519998 | Antimicrobial activity against Streptococcus pyogenes | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID422665 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1077 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID557980 | Antimicrobial activity in Clostridium cadaveris by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID206810 | In vitro antibacterial activity against the aerobic Staphylococcus pneumoniae III(Strain UC no.3213) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID534341 | Antimicrobial activity against Burkholderia pseudomallei Bp227 harboring deleted (bpeAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID531561 | Antibacterial activity against coagulase-negative Staphylococcus sciuri obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID573572 | Antibacterial activity against beta-lactamase producing Bacteroides uniformis by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID278871 | Increase in lactate production in MG63 cells at 400 ug/ml by ELISA relative to control | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID562401 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus Group F clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID554550 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC879-2 preincubated with 2 ug/ml erythromycin for 20 to 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID433014 | Antibacterial activity against Streptococcus agalactiae isolated from patient with diabetic foot infection after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID571790 | Antibacterial activity against Clostridium clostridioforme by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1879577 | Antibacterial activity against Veillonella parvula ATCC 17745 MMX 1272 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID522185 | Antimicrobial activity against Eubacterium contortum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID323027 | Antibacterial activity against Corynebacterium diphtheriae after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID534430 | Antimicrobial activity against Parvimonas micra VPI 5464-1 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID524824 | Antibacterial activity against erythromycin resistant Campylobacter sp. by agar plate dilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID531795 | Antibacterial activity against SCCmec type 4 genotype-positive and methicillin-resistant Staphylococcus aureus by CLSI method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. |
| AID573564 | Antibacterial activity against beta-lactamase producing Bacteroides vulgatus assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID554545 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC879 preincubated with 2 ug/ml erythromycin for 20 to 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID534444 | Antimicrobial activity against Actinomyces odontolyticus GAI 91002 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID574486 | Antimicrobial activity against Bacteroides caccae after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID574766 | Antimicrobial activity against Finegoldia magna assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID428139 | Antimicrobial activity against wild-type Streptococcus pneumoniae PC13 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. |
| AID522210 | Antimicrobial activity against Clostridium paraputrificum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID565759 | Antimicrobial activity against oxacillin-resistant Staphylococcus aureus clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID425085 | Antimicrobial activity against beta lactamase-positive Prevotella denticola isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID528847 | Antimicrobial activity against methicillin-resistant Staphylococcus epidermidis isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID157259 | In vitro antibacterial activity against the anaerobic Peptostreptococcus anaerobius(Strain UC no.6321) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID520395 | Antibacterial activity against erm(B) and mef(E)-positive Streptococcus pneumoniae isolate Sweden 15A-25 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID573594 | Antibacterial activity against Fusobacterium varium assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID535016 | Bactericidal activity against daptomycin-nonsusceptible Staphylococcus aureus assessed as antibiotic concentration that reduced the number of viable cells by =>99.9% by colony count method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID1879576 | Antibacterial activity against Treponema denticola ATCC 35405 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID529876 | Antimicrobial activity against Enterococcus faecalis JH2-2 harboring pAT392 containing mph(B) and rdmC-like gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID322786 | Antimicrobial activity against Bacteroides thetaiotaomicron assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID555308 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis 074 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID522135 | Antimicrobial activity against Bacteroides distasonis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID574496 | Antimicrobial activity against Bacteroides fragilis assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID125737 | Bioactivity in abscess, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 45 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID285356 | Decrease in Panton-Valentine leukocidin level in community acquired methicillin-resistant Staphylococcus aureus HT20040332 in CYY medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID586055 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type U3 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID557738 | Antimicrobial activity in Peptoniphilus asaccharolyticus by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID531559 | Antibacterial activity against coagulase-negative Staphylococcus saprophyticus obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID585157 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA A2058G mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID528976 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus isolated from ICU patient urine assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID559485 | Antibacterial activity against Bacteroides fragilis by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID557992 | Antimicrobial activity in Clostridium sordellii by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID404895 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB10 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID573583 | Antibacterial activity against beta-lactamase producing Bacteroides caccae assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID323003 | Antibacterial activity against drug-resistant Propionibacterium acnes P425:1 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID520000 | Antimicrobial activity against Moraxella catarrhalis | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID565758 | Antimicrobial activity against Staphylococcus epidermidis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID372523 | Antimalarial activity as 3rd generation parasitaemia against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 96hrs at 25 nM dosed 12-48 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID529867 | Antimicrobial activity against Streptococcus uberis UCN61 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID531527 | Antibacterial activity against Bacteroides vulgatus isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID533373 | Antimicrobial activity against Bacteroides eggerthii by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID574050 | Antibacterial activity against beta-lactamase producing Finegoldia magna by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID562932 | Antimicrobial activity against Clostridium difficile 6425 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID534435 | Antimicrobial activity against Staphylococcus saccharolyticus ATCC 14953 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID534454 | Antimicrobial activity against Lactobacillus brevis subsp. brevis JCM 1059 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID396028 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID533392 | Antimicrobial activity against Clostridium perfringens assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID342090 | Effect on growth of epidemic Clostridium difficile BI9 in CF1 mouse assessed as increase in bacterial density in cecal content at 1.4 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID522138 | Antimicrobial activity against Bacteroides uniformis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID508421 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2686 harboring mutation in L4 ribosomal protein after 14 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID522143 | Antimicrobial activity against Prevotella intermedia under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID278671 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5736 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID534339 | Antimicrobial activity against Burkholderia pseudomallei 1026b after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID433182 | Antibacterial activity against Corynebacterium aurimucosum isolated from patient with diabetic foot infection assessed as percent resistant isolates after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID559493 | Antibacterial activity against Fusobacterium sp. assessed as percent susceptible isolates by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID581666 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient in cation-adjusted MH 2 broth assessed as log reduction of extracellular CFU level after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID554551 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MAB30 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID327750 | Antibacterial activity against Bacteroides fragilis by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Novel antibacterial azetidine lincosamides. |
| AID562939 | Effect on fbp69 gene expression in Clostridium difficile 6425 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID509630 | Antimicrobial activity against Staphylococcus aureus RN4220 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID508368 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID534464 | Antimicrobial activity against Bacteroides fragilis GAI 7955 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID562937 | Upregulation of cwp84 gene expression in Clostridium difficile CD07-259 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID562605 | Antimicrobial activity against Staphylococcus aureus clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID557918 | Antimicrobial activity against Mycobacterium abscessus isolate MC879 at day 5 preincubated with 0.1 ug/ml for 3 days by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID559486 | Antibacterial activity against Clostridium perfringens by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID522157 | Antimicrobial activity against Fusobacterium varium under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID444057 | Fraction escaping hepatic elimination in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID574949 | Antimicrobial activity against Streptococcus pneumoniae serotype 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID557428 | Antimicrobial activity in Bacteroides uniformis by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID530126 | Antimicrobial activity against community acquired methicillin-resistant Staphylococcus aureus 144 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. |
| AID535642 | Antimicrobial activity against Group B streptococcus serotype VI N4 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID425986 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3243 after 41 passages with clarithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID565191 | Antimicrobial activity against Acinetobacter baumannii ATCC 19606 expressing open reading frame orf3 encoded efflux pump CraA by Etest | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii. |
| AID557686 | Antimicrobial activity in Prevotella veroralis by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID574952 | Antimicrobial activity against Streptococcus pneumoniae serotype 11A by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID425090 | Antimicrobial activity against Porphyromonas levii isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID625290 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver fatty | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID72250 | In vitro antibacterial activity against the anaerobic Fusobacterium necrophorum (Strain UC no.6568) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID508383 | Antibacterial activity against Streptococcus pyogenes harboring mef(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID508419 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 24 harboring erm(B) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID522206 | Antimicrobial activity against Clostridium celerecrescens under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID765062 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. |
| AID535025 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-24 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID561755 | Antibacterial activity against Methicillin-sensitive Staphylococcus aureus assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID739304 | Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 assessed as growth inhibition by CLSI broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Substituted 1,6-diphenylnaphthalenes as FtsZ-targeting antibacterial agents. |
| AID625285 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID433195 | Antibacterial activity against Streptococcus agalactiae isolated from patient with diabetic foot infection assessed as percent resistant isolates after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID522162 | Antimicrobial activity against Parvimonas micra under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID508377 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae harboring erm(B) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID520609 | Antimicrobial activity against Group D Streptococcus sp. clinical isolates assessed as resistant isolates | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Prevalence of the erm(T) gene in clinical isolates of erythromycin-resistant group D Streptococcus and Enterococcus. |
| AID433368 | Antibacterial activity against Finegoldia magna isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID545050 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ250 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID574041 | Antibacterial activity against beta-lactamase producing Peptoniphilus asaccharolyticus by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID581667 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient infected in human THP-1 cells assessed as log reduction of intracellular CFU level after 24 hrs in presence of thymidine | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID522375 | Antimicrobial activity against Eubacterium limosum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID278490 | Antibacterial activity against Pneumococcus DAW51 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID1879550 | Antibacterial activity against Bacteroides gracilis ATCC 33236 MMX 1270 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID585163 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA C2571G mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID584123 | Antimicrobial activity against Staphylococcus aureus RN4220 carrying pAFS11-apmA, erm(B), tet(L), dfrK, aadD resistance genes by CLSI M31-A3 method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. |
| AID283554 | Antimicrobial activity against Streptococcus pneumoniae PC13 isolate with L4 69GTG71 to TPS mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID283550 | Antimicrobial activity against Streptococcus pneumoniae BSF-11524 isolate with erm(B) and L4 mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID518015 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus assessed as percent resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | In vitro activity of fidaxomicin (OPT-80) tested against contemporary clinical isolates of Staphylococcus spp. and Enterococcus spp. |
| AID425104 | Antimicrobial activity against Clostridium ramosum isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID528705 | Antibacterial activity against Streptococcus mitis clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID422675 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3009 after 25 passages with clarithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID534682 | Antimicrobial activity against Veillonella dispar ATCC 17748 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID531719 | Antibacterial activity against Bacteroides fragilis isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID522201 | Antimicrobial activity against Clostridium hathewayi under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID573600 | Antibacterial activity against Fusobacterium mortiferum assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID1698698 | Antibacterial activity against Clostridioides difficile ATCC 700057 by CLSI method | 2020 | Bioorganic & medicinal chemistry, 11-15, Volume: 28, Issue:22 | Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors. |
| AID1079937 | Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source] | |||
| AID509631 | Antimicrobial activity against Staphylococcus aureus RN4220 transformant carrying plasmid pKKS25 and expressing erm(T), dfrK and tet(L) genes by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID565760 | Antimicrobial activity against oxacillin-susceptible Staphylococcus aureus clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID323660 | Antibacterial activity against Peptostreptococcus stomatis | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antimicrobial susceptibilities of Peptostreptococcus anaerobius and the newly described Peptostreptococcus stomatis isolated from various human sources. |
| AID342064 | Antimicrobial activity against epidemic Clostridium difficile BI9 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID528836 | Antimicrobial activity against vancomycin-resistant Enterococcus sp. isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID425094 | Antimicrobial activity against beta lactamase-positive Fusobacterium mortiferum isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID519140 | Antimicrobial activity against community-acquired methicillin resistant Staphylococcus aureus expressing PVL and mec type IV gene assessed as resistant strains by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. |
| AID375938 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 after 24 hrs by broth microdilution method | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Antibacterial, partially acetylated oligorhamnosides from Cleistopholis patens. |
| AID323035 | Antibacterial activity against Streptococcus equi subsp. zooepidemicus after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID424329 | Antimicrobial activity against Dialister propionicifaciens assessed as susceptibility breakpoint by CLSI method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID1870152 | Antibacterial activity against wild type Staphylococcus aureus 4738/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID1909750 | Toxicity in Balb/c mouse infected with methicillin-resistant Staphylococcus aureus USA300 assessed as chronic inflammatory response at 25 mg/kg, ip administered 2 days post infection twice daily and measured after 5 days post compound treatment by H and E | 2022 | Journal of medicinal chemistry, 05-12, Volume: 65, Issue:9 | Mechanistic Studies and |
| AID433017 | Antibacterial activity against Bacteroides fragilis isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID561256 | Antibacterial activity against Streptococcus pyogenes assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID565754 | Antimicrobial activity against oxacillin-susceptible Staphylococcus haemolyticus clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID565739 | Antimicrobial activity against Streptococcus pyogenes clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID585879 | Antimicrobial activity against Staphylococcus aureus clone 1-1 harboring staphylococcal cassette chromosome mec element type 5 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID1424067 | Antibiotic activity against methicillin-resistant Staphylococcus aureus isolate CAIRD142 by broth microdilution assay or Alamar blue dye based colorimetric assay | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture. |
| AID1879575 | Antibacterial activity against Prevotella intermedia ATCC 25611 MMX 3002 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID574756 | Antimicrobial activity against Anaerococcus prevotii assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID1906417 | Antibacterial activity against imipenem resistant Klebsiella pneumoniae ATCC BAA 1705 assessed as reduction in microbial growth incubated for 24 hrs by microbroth dilution method | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Amphiphilic cyclic peptide [W |
| AID206901 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6691) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID581671 | Antibacterial activity against normal phenotype Staphylococcus aureus in cation-adjusted MH 2 broth at pH 5.5 after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID524895 | Antibacterial activity against macrolide resistant and mef(I)-positive Streptococcus pneumoniae by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. |
| AID497967 | Cmin in po dosed human co-treated with rifampin | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Continuous clindamycin infusion, an innovative approach to treating bone and joint infections. |
| AID533393 | Antimicrobial activity against Clostridium innocuum by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID571822 | Antibacterial activity against Bifidobacterium pseudolongum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID278498 | Antibacterial activity against Pneumococcus DAW68 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID433015 | Antibacterial activity against Streptococcus dysgalactiae subsp. equisimilis isolated from patient with diabetic foot infection after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID585158 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA G2032C mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID155770 | In vitro antibacterial activity against the aerobic Pasteurella multocida (Strain UC no.264) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID519482 | Antibacterial activity against Staphylococcus aureus T2019 with G2576T mutation in 23S rRNA genes by Etest method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances. |
| AID535032 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-76 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID1909752 | Toxicity in Balb/c mouse infected with methicillin-resistant Staphylococcus aureus USA300 assessed as hemorrhage at 25 mg/kg, ip administered 2 days post infection twice daily and measured after 5 days post compound treatment by H and E staining based his | 2022 | Journal of medicinal chemistry, 05-12, Volume: 65, Issue:9 | Mechanistic Studies and |
| AID562361 | Antimicrobial activity against penicillin-intermediate Streptococcus pneumoniae clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID520394 | Antibacterial activity against mef(E)-positive Streptococcus pneumoniae isolate Spain 9V-3 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID522214 | Antimicrobial activity against Clostridium symbiosum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID530127 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus ATCC 25923 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. |
| AID424319 | Antimicrobial activity against Dialister pneumosintes by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID535003 | Antimicrobial activity against vancomycin-intermediate Staphylococcus aureus assessed as resistant isolates by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID342089 | Effect on growth of nonepidemic Clostridium difficile J29 in CF1 mouse assessed as increase in bacterial density in cecal content at 1.4 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID41426 | In vitro activity against Bacteroides thetaiotaomicron (106) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID433163 | Antibacterial activity against Clostridium sphenoides isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID433191 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus isolated from patient with diabetic foot infection assessed as percent resistant isolates after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID546209 | Antimicrobial activity against Staphylococcus aureus 2171 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Identification of the novel dfrK-carrying transposon Tn559 in a porcine methicillin-susceptible Staphylococcus aureus ST398 strain. |
| AID531560 | Antibacterial activity against coagulase-negative Staphylococcus cohnii obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID396032 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pAP3 plasmid containing Enterobacter aerogenes acrR gene by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID41408 | In vitro activity against Bacteroides loescheii (ATCC 15930). | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID545049 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ249 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID565734 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus Group C clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID571792 | Antibacterial activity against Clostridium hathewayi by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID557714 | Antimicrobial activity in Fusobacterium necrophorum by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID323021 | MBC/MIC ratio of Propionibacterium acnes EG7NS | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID534427 | Antimicrobial activity against Anaerococcus prevotii ATCC 9321 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID560249 | Antibacterial activity against Staphylococcus aureus RN4220 harboring tet(L), dfrK gene by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID1870151 | Antibacterial activity against wild type Staphylococcus aureus 4717/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID522137 | Antimicrobial activity against Bacteroides ovatus under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID562398 | Antimicrobial activity against Staphylococcus aureus clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID433352 | Antibacterial activity against Bacteroides vulgatus isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID561342 | Antibacterial activity against Beta-hemolytic Streptococcus group A by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID557750 | Antimicrobial activity in Lactobacillus by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID278858 | Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID521968 | Antibacterial activity against Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID508464 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2094 harboring erm(A) gene after 22 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID425107 | Antimicrobial activity against Clostridium sordellii isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID533381 | Antimicrobial activity against Bacteroides nordii by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID571802 | Antibacterial activity against Clostridium disporicum by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID557984 | Antimicrobial activity in Clostridium bifermentans by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID572010 | Antibacterial activity against Fusobacterium varium by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID129550 | In vivo antibacterial activity against Staphylococcus aureus(UC 76) infected mice after oral administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID531557 | Antibacterial activity against coagulase-negative Staphylococcus hominis obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID508413 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 1635 harboring erm(A) gene after 14 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID562359 | Antimicrobial activity against penicillin-susceptible Streptococcus pneumoniae clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID721792 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus 8325-4 assessed as growth inhibition after 24 hrs by CLSI broth microdilution method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. |
| AID323006 | Antibacterial activity against drug-resistant Propionibacterium acnes SW54EA after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID522186 | Antimicrobial activity against Eubacterium cylindroides under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID531525 | Antibacterial activity against Bacteroides ovatus isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID342093 | Increase in toxin level in nonepidemic Clostridium difficile J29 infected CF1 mouse at 2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID535645 | Antimicrobial activity against Group B Streptococcus serotype Ia N1 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID369438 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID565732 | Antimicrobial activity against erythromycin-susceptible Streptococcus Group G clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID96266 | In vitro antibacterial activity against the aerobic Klebsiella pneumoniae (Strain UC no.58) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID433008 | Antibacterial activity against Corynebacterium xerosis isolated from patient with diabetic foot infection after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID583885 | Antibacterial activity against hospital-associated methicillin-resistant Staphylococcus aureus isolate 56 (494) by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID522176 | Antimicrobial activity against Actinomyces meyeri under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID285347 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20010734 in CCY medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID433192 | Antibacterial activity against Staphylococcus epidermidis isolated from patient with diabetic foot infection assessed as percent resistant isolates after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID545044 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ078 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID425078 | Antimicrobial activity against beta lactamase-positive Bacteroides vulgatus isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID428140 | Antimicrobial activity against Streptococcus pneumoniae PC13 transformant harboring 136-bp deletion in erm(B) gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. |
| AID535015 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus assessed as susceptible isolates by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID581654 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient at pH 7.4 after 48 hrs by broth microdilution method in absence of thymidine | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID1079939 | Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source] | |||
| AID518017 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as percent resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | In vitro activity of fidaxomicin (OPT-80) tested against contemporary clinical isolates of Staphylococcus spp. and Enterococcus spp. |
| AID1079948 | Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source] | |||
| AID586049 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type U6 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID425088 | Antimicrobial activity against Porphyromonas asaccharolyticus isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID562220 | Antimicrobial activity against Desulfovibrio sp. by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID531577 | Antibacterial activity against Gemella spp. obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID528723 | Antibacterial activity against Streptococcus constellatus clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID428291 | Antimicrobial activity against Acinetobacter baumannii BM4652 expressing adeABC adeIJK double mutant isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID1906415 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as reduction in microbial growth incubated for 24 hrs by microbroth dilution method | 2022 | European journal of medicinal chemistry, May-05, Volume: 235 | Amphiphilic cyclic peptide [W |
| AID561340 | Antibacterial activity against Methicillin-sensitive Staphylococcus aureus by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID717274 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 by CLSI protocol based broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. |
| AID581655 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient at pH 7.4 after 48 hrs by broth microdilution method in presence of thymidine | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID508384 | Antibacterial activity against Streptococcus pyogenes harboring erm(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID565755 | Antimicrobial activity against Staphylococcus haemolyticus clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID574484 | Antimicrobial activity against Bacteroides thetaiotaomicron after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID422667 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1076 after 14 passages with Telithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID522211 | Antimicrobial activity against Clostridium sordellii under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID535637 | Antimicrobial activity against Group B streptococcus serotype Ib R3 harboring Q557E, A400V mutations in PBP 2X and T567I, G539E mutations in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID573819 | Antibacterial activity against Veillonella parvula by by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID508428 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 7127 harboring S20N mutation in L4 ribosomal protein and A105V mutation in L22 ribosomal protein after 29 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID533413 | Antimicrobial activity against Peptoniphilus asaccharolyticus by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID533400 | Antimicrobial activity against Clostridium paraputrificum assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID573786 | Antibacterial activity against Prevotella melaninogenica by by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID129540 | In vivo antibacterial activity against Escherichia coli (UC no 311) infected mice after sc administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID571820 | Antibacterial activity against Bifidobacterium infantis by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID533361 | Antimicrobial activity against Bacteroides thetaiotaomicron by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID561734 | Antibacterial activity against Beta-hemolytic Streptococcus group B assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID404936 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus sp. by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID433159 | Antibacterial activity against Clostridium cadaveris isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID322994 | Antibacterial activity against drug-resistant Propionibacterium acnes OK8/97 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID369443 | Antibacterial activity against penicillin-susceptible Streptococcus pneumoniae after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID424420 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus HIP14300 isolated from patients foot wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID565737 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus pyogenes clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID520398 | Antibacterial activity against mef-positive Streptococcus pneumoniae isolates assessed as resistance incidence by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID572003 | Antibacterial activity against Bacteroides fragilis by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID571815 | Antibacterial activity against Actinomyces naeslundii by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1870147 | Antibacterial activity against wild type Staphylococcus aureus 4482/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID557444 | Antimicrobial activity in Prevotella melaninogenica by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID529874 | Antimicrobial activity against Enterococcus faecalis JH2-2 harboring pAT392 containing rdmC-like gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID571832 | Antibacterial activity against Ruminococcus albus by CLSI M11-A6 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID573595 | Antibacterial activity against Fusobacterium nucleatum assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID508369 | Antibacterial activity against Streptococcus pneumoniae harboring erm(B) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID534436 | Antimicrobial activity against Streptococcus constellatus ATCC 27923 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID508454 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2368 harboring erm(B) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID532677 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates assessed as intermediate resistant isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID562366 | Antimicrobial activity against erythromycin-susceptible Streptococcus Group F clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID433149 | Antibacterial activity against Bacteroides thetaiotaomicron isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID433190 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolated from patient with diabetic foot infection assessed as percent resistant isolates after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID206900 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6690) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID574956 | Antimicrobial activity against multiple drug resistant Streptococcus pneumoniae serotype 6B by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID562379 | Antimicrobial activity against Streptococcus agalactiae clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1879555 | Antibacterial activity against Bifidobacterium ATCC 15698 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID574005 | Antibacterial activity against beta-lactamase producing Clostridium septicum assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID278577 | Inhibition of Plasmodium falciparum FCK2 growth as [3H]hypoxanthine uptake after 96 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID557792 | Antimicrobial activity against Streptococcus pyogenes clinical isolate expressing mosaic variant of mef gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Characterization of macrolide efflux pump mef subclasses detected in clinical isolates of Streptococcus pyogenes isolated between 1999 and 2005. |
| AID508415 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 1635 harboring erm(A) gene after 49 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID322998 | Antibacterial activity against drug-resistant Propionibacterium acnes SW11 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID535037 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-404 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID1879548 | Antibacterial activity against metronidazole-resistant Bacteroides fragilis MMX 3387 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID586052 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type 2 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID278853 | Cytotoxicity against primary human osteoblasts at 400 ug/ml assessed as LDH release after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID548255 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID425114 | Antimicrobial activity against beta lactamase-positive Fusobacterium nucleatum isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID433356 | Antibacterial activity against Porphyromonas somerae isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID1879566 | Antibacterial activity against Peptoniphilus asaccharolyticus ATCC 29743 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID557420 | Antimicrobial activity in Bacteroides vulgatus by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID562931 | Antimicrobial activity against Clostridium difficile 6269 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID422683 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 37 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID565740 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus agalactiae clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID444056 | Fraction escaping gut-wall elimination in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID278488 | Antibacterial activity against Pneumococcus DAW26 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID528850 | Antimicrobial activity against methicillin-susceptible Staphylococcus epidermidis isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID574516 | Antimicrobial activity against Bacteroides ovatus assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID534465 | Antimicrobial activity against Bacteroides fragilis GAI 10150 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID575082 | Antimicrobial activity against multiple drug resistant Streptococcus pneumoniae serotype 19A assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID1079933 | Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is | |||
| AID425975 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 24 after 14 passages with Telithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID534670 | Antimicrobial activity against Prevotella oralis ATCC 33269 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID534678 | Antimicrobial activity against Desulfovibrio desulfuricans ATCC 29577 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID1241206 | Inhibition of pre-miR-17 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID584994 | Antibacterial activity against Staphylococcus aureus XU21-T1 harboring cfr-encoding conjugative pSCFS7 and fexA by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Identification and characterization of the multidrug resistance gene cfr in a Panton-Valentine leukocidin-positive sequence type 8 methicillin-resistant Staphylococcus aureus IVa (USA300) isolate. |
| AID1079931 | Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source] | |||
| AID562579 | Antimicrobial activity against erythromycin-susceptible Streptococcus Group C clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID574494 | Antimicrobial activity against Bacteroides fragilis assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID562582 | Antimicrobial activity against erythromycin-susceptible Streptococcus pyogenes clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID531520 | Antibacterial activity against Bacteroides fragilis assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID625284 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID425993 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3243 after 50 passages by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID548474 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID562936 | Upregulation of cwp84 gene expression in Clostridium difficile 6425 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID433362 | Antibacterial activity against Clostridium innocuum isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID534345 | Antimicrobial activity against Burkholderia pseudomallei Bp175 harboring mini-Tn7T-P1-bpeR+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID283660 | Antimicrobial activity against Haemophilus influenzae CDS23 mutant overexpressing Def by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number. |
| AID561247 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID495948 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID1459987 | In vivo antiparasitic activity against Pneumocystis sp. assessed as fever clearance time | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Comprehensive review on various strategies for antimalarial drug discovery. |
| AID575083 | Antimicrobial activity against multiple drug resistant Streptococcus pneumoniae serotype 19F assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID534442 | Antimicrobial activity against Clostridium sordellii ATCC 9714 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID557682 | Antimicrobial activity in Prevotella oralis group by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID285350 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20040332 in CCY media | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID342084 | Effect on growth of nonepidemic Clostridium difficile ATCC 9689 in CF1 mouse assessed as increase in bacterial density in cecal content at 2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID574730 | Antimicrobial activity against Porphyromonas asaccharolytica after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID1870139 | Antibacterial activity against wild type methicillin resistant Staphylococcus aureus 5017/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID529877 | Antimicrobial activity against Escherichia coli AG100A harboring empty vector by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID561243 | Antibacterial activity against methicillin-susceptible Staphylococcus epidermidis assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID508458 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2094 harboring erm(A) gene after 43 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID562940 | Effect on fbp69 gene expression in Clostridium difficile CD07-259 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID41254 | In vitro activity against Bacteroides fragilis (UC-2) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID30566 | In vitro antibacterial activity against the anaerobic Actinomyces naeslundii (Strain UC no.5920) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID206905 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6695) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID547759 | Antimicrobial activity against invasive Streptococcus intermedius obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID50844 | In vitro antibacterial activity against the anaerobic Clostridium difficile (Strain UC no.6857) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID422672 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3009 after 19 passages with moxifloxacin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID409954 | Inhibition of mouse brain MAOA | 2008 | Journal of medicinal chemistry, Nov-13, Volume: 51, Issue:21 | Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. |
| AID444051 | Total clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID206903 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6693) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID433010 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus isolated from patient with diabetic foot infection after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID327751 | Inhibition of protein synthesis in Escherichia coli by transcription/translation inhibition assay | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Novel antibacterial azetidine lincosamides. |
| AID422649 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3676 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID574551 | Decrease in delta toxin levels in Staphylococcus aureus Sanger 252 at subinhibitory concentrations after 24 hrs by RP-HPLC/ESI- MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID562583 | Antimicrobial activity against Streptococcus pyogenes clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID278486 | Antibacterial activity against Pneumococcus DAW22 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID129539 | In vivo antibacterial activity against Bacteroides fragilis (UC no 6428) infected mice after sc administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID508450 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 2132 after 28 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID508474 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 237 harboring mutation in L4 ribosomal protein after 43 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID530125 | Antimicrobial activity against community acquired methicillin-resistant Staphylococcus aureus 146 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. |
| AID534429 | Antimicrobial activity against Finegoldia magna ATCC 29328 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID585174 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA A2572U1 mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID559496 | Antibacterial activity against Propionibacterium acnes assessed as percent susceptible isolates by CLSI M11-A7 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. |
| AID567569 | Antimicrobial activity against Staphylococcus aureus RN4220 | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. |
| AID545047 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ088 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID545045 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ082 from patient bile by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID285357 | Decrease in Panton-Valentine leukocidin level in community acquired methicillin-resistant Staphylococcus aureus HT20041010 in CYY medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID157240 | In vitro antibacterial activity against the anaerobic Peptoccus aerogenes (Strain UC no.6319) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID528846 | Antimicrobial activity against methicillin-resistant Staphylococcus epidermidis isolated from ICU patient urine assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID534445 | Antimicrobial activity against Bifidobacterium adolescentis ATCC 15703 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID573565 | Antibacterial activity against beta-lactamase producing Bacteroides vulgatus assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID565078 | Antibacterial activity against community-acquired methicillin-resistant Staphylococcus aureus 156 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Pharmacodynamic profile of tigecycline against methicillin-resistant Staphylococcus aureus in an experimental pneumonia model. |
| AID206902 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6692) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID206906 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6696) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID205739 | In vitro antibacterial activity against the aerobic Staphylococcus epidermidis (Strain UC no.3389) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID717273 | Antimicrobial activity against methicillin-sensitive Staphylococcus aureus 8325-4 by CLSI protocol based broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. |
| AID585164 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA G2576U mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID625281 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID425973 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 2527 after 50 passages by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID520397 | Antibacterial activity against erm(B) and mef(E)-positive Streptococcus pneumoniae isolate Spain 6B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID573599 | Antibacterial activity against Fusobacterium nucleatum assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID534459 | Antimicrobial activity against Lactobacillus salivarius subsp. salivarius JCM 1231 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID574043 | Antibacterial activity against beta-lactamase producing Peptoniphilus asaccharolyticus assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID129551 | In vivo antibacterial activity against Streptococcus pneumoniae I (UC 41) infected mice after sc administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID535258 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-6 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID562412 | Antimicrobial activity against Streptococcus Group G clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID573796 | Antibacterial activity against Prevotella bivia assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID508426 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 7127 harboring S20N mutation in L4 ribosomal protein and A105V mutation in L22 ribosomal protein after 16 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID422648 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3676 after 50 passages by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID516168 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as susceptible isolates by EUCAST method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID533416 | Antimicrobial activity against Peptoniphilus asaccharolyticus assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID323014 | Antibacterial activity against drug-resistant Propionibacterium acnes QK6/92 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID565193 | Antimicrobial activity against efflux pump CraA deficient Acinetobacter baumannii JVAB01 receiving pJV103 harboring open reading frame orf3 encoded efflux pump CraA by Etest | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii. |
| AID157256 | In vitro activity against Peptostreptococcus sp.(TB-11) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID535254 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-2 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID508405 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 3665 harboring mef(A) gene after 26 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID342066 | Antimicrobial activity against fluoroquinolone-resistant epidemic Clostridium difficile NAP1 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID425108 | Antimicrobial activity against Clostridium paraputrificum isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID433360 | Antibacterial activity against Clostridium cadaveris isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID525143 | Antimicrobial activity against linezolid-resistant Staphylococcus aureus isolate 004-737X expressing cfr and ermA gene isolated from paraplegic patient by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States. |
| AID375939 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 78-13607A after 24 hrs by broth microdilution method | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Antibacterial, partially acetylated oligorhamnosides from Cleistopholis patens. |
| AID522202 | Antimicrobial activity against Clostridium baratii under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID521967 | Antibacterial activity against Campylobacter coli assessed as resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID562373 | Antimicrobial activity against Streptococcus Group C clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID495944 | Antimicrobial activity against erythromycin, lincomycin, clindamycin resistant Staphylococcus epidermidis isolate 1036UL harboring ermC vgaALC gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID522153 | Antimicrobial activity against Porphyromonas somerae under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID433150 | Antibacterial activity against Bacteroides uniformis isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID508448 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 2132 after 50 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID575145 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate NRS71 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID721789 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 assessed as growth inhibition after 24 hrs by CLSI broth microdilution method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. |
| AID533368 | Antimicrobial activity against Bacteroides uniformis assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID528841 | Antimicrobial activity against penicillin-resistant Streptococcus pneumoniae isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID520291 | Antimicrobial activity against Staphylococcus aureus 2548 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID327753 | Antibacterial activity against Staphylococcus aureus Smith infected po dosed mouse septicemia model | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Novel antibacterial azetidine lincosamides. |
| AID404897 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB30 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID574768 | Antimicrobial activity against Finegoldia magna assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID555304 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 507 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID71151 | In vitro antibacterial activity against the anaerobic Eubacterium lentum(Strain UC no.6522) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID534456 | Antimicrobial activity against Lactobacillus fermentum JCM 1173 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID206908 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.76) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID424330 | Antimicrobial activity against Dialister invisus assessed as susceptibility breakpoint by CLSI method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID372462 | Antimalarial activity as 3rd generation ring-stage chloroquine-sensitive Plasmodium falciparum 3D7 after 48 hrs dose then 48 hrs drug-free | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID768037 | Antibacterial activity against Streptococcus pyogenes Serotype M12 MGAS9429 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID540209 | Volume of distribution at steady state in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID547521 | Antimicrobial activity against Streptococcus anginosus obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on brain heart infusion agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID557988 | Antimicrobial activity in Clostridium innocuum by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID372525 | Antimalarial activity as 3rd generation parasitaemia against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes after 96 hr at 25 nM dosed 24-48 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID424321 | Antimicrobial activity against Dialister pneumosintes assessed as susceptibility breakpoint by CLSI method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID562393 | Antimicrobial activity against oxacillin-resistant Staphylococcus epidermidis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID433169 | Antibacterial activity against Peptostreptococcus anaerobius isolated from patient with diabetic foot infection after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID575009 | Antimicrobial activity against Eubacterium sp. assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID508443 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2686 harboring mutation in L4 ribosomal protein after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID534681 | Antimicrobial activity against Veillonella parvula ATCC 10790 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID574774 | Antimicrobial activity against Clostridium perfringens assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID425105 | Antimicrobial activity against Clostridium bifermentans isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID534434 | Antimicrobial activity against Gemella morbillorum ATCC 27824 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID323018 | Antibacterial activity against drug-resistant Propionibacterium acnes P95 after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID508417 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2686 harboring mutation in L4 ribosomal protein after 22 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID342244 | Increase in toxin level in nonepidemic Clostridium difficile J29 infected CF1 mouse at 0.2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID51140 | In vitro antibacterial activity against the anaerobic Clostridium tetani(Strain UC no.6521) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID424332 | Antimicrobial activity against Dialister invisus assessed as susceptibility breakpoint by CA-SFM method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID562369 | Antimicrobial activity against erythromycin-susceptible Streptococcus Group G clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID575102 | Antimicrobial activity against Streptococcus pneumoniae serotype 19F assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID278870 | Increase in lactate production in primary human osteoblasts by ELISA relative to control | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID342257 | Effect on growth of fluoroquinolone-susceptible epidemic Clostridium difficile ATCC 9689 in CF1 mouse assessed as increase in bacterial density in cecal content dosed sc for 5 days | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID428295 | Antimicrobial activity against Acinetobacter baumannii BM4579 expressing adeIJK genes with pAT807 isolated from patient with urinary tract infection by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID534668 | Antimicrobial activity against Prevotella melaninogenica JCM 6325 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID534671 | Antimicrobial activity against Prevotella oris ATCC 33573 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID573558 | Antibacterial activity against beta-lactamase producing Bacteroides thetaiotaomicron assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID157387 | In vitro activity against Peptostreptococcus micros (ATCC 33270). | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID129548 | In vivo antibacterial activity against Proteus vulgaris(UC 347) infected mice after oral administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID555513 | Antibacterial activity against methicillin-resistant, Linezolid non-susceptible coagulase-negative Staphylococcus epidermidis 345 after 50 passages by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID342067 | Antimicrobial activity against fluoroquinolone-susceptible nonepidemic Clostridium difficile strain6 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID534460 | Antimicrobial activity against Bacteroides fragilis GAI 5562 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID1197134 | Plasma protein binding in human by equilibrium dialysis assay | 2015 | Journal of medicinal chemistry, Feb-12, Volume: 58, Issue:3 | Structure-activity relationship for the oxadiazole class of antibiotics. |
| AID561239 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID278585 | Reduced apicoplast DNA/nuclear DNA ratio in Plasmodium falciparum FCK2 at 10 uM after 72 hrs by competitive PCR | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID129543 | In vivo antibacterial activity against Klebsiella pneumoniae(UC 58) infected mice after oral administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID528970 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID530128 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. |
| AID584121 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ST398 isolate 11 containing apmA, erm(B), tet(L), tet(M), tet(K), dfrK, aadD, mecA, blaZ resistance genes by CLSI M31-A3 method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. |
| AID1241208 | Inhibition of pre-miR-21 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID555318 | Antibacterial activity against methicillin-susceptible, vancomycin-intermediate Staphylococcus aureus 505 after 39 passages by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID557996 | Antimicrobial activity in Clostridium butyricum by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID534340 | Antimicrobial activity against Burkholderia pseudomallei Bp50 harboring deleted (amrRAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID575946 | Antimicrobial activity against erythromycin-resistant Streptococcus pneumoniae assessed as susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates. |
| AID495945 | Antimicrobial activity against erythromycin, lincomycin resistant Staphylococcus haemolyticus isolate 113OL harboring msrA lnuA gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID548740 | Antimicrobial activity against Oxacillin-resistant coagulase-negative Staphylococcus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1879553 | Antibacterial activity against metronidazole-resistant Bacteroides vulgatus 3490 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID585166 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA C2499A2 mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID534466 | Antimicrobial activity against carbapenemase-producing Bacteroides fragilis GAI 30079 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID565077 | Antibacterial activity against community-acquired methicillin-resistant Staphylococcus aureus 144 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Pharmacodynamic profile of tigecycline against methicillin-resistant Staphylococcus aureus in an experimental pneumonia model. |
| AID554544 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC720 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID533866 | Antibacterial activity against toxin-positive Clostridium difficile clinical isolate assessed as percent of susceptible isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of OPT-80 tested against clinical isolates of toxin-producing Clostridium difficile. |
| AID535643 | Antimicrobial activity against Group B streptococcus serotype III N3 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID50727 | In vitro antibacterial activity against the anaerobic Clostridium botulinum A(Strain UC no.6506) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID721790 | Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 assessed as growth inhibition after 24 hrs by CLSI broth microdilution method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. |
| AID562928 | Antimicrobial activity against Clostridium difficile ATCC 43603 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID574965 | Antimicrobial activity against Actinomyces odontolyticus assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID583894 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus isolate 440 (A6298) by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID531518 | Antibacterial activity against Bacteroides uniformis assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID562599 | Antimicrobial activity against Staphylococcus haemolyticus clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID322993 | Antibacterial activity against drug-resistant Propionibacterium acnes D-04/97 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID423274 | Antibacterial activity against azithromycin-tolerant 0.01 MOI Chlamydia trachomatis L2AZM#31 harboring mutation in bacterial ribosomal protein L4 infected in mouse L2 cells treated 2 hrs after infection measured on day 7 by plaque assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2. |
| AID404903 | Antibacterial activity against Streptococcus bovis ATCC 33317 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID322992 | Antibacterial activity against drug-resistant Propionibacterium acnes SW26 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID694207 | Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 by CLSI broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 22, Issue:22 | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. |
| AID157258 | In vitro activity against Peptostreptococcus anaerobius (ATCC 27337) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID531510 | Antibacterial activity against Bacteroides stercoris assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID278582 | Reduction in Plasmodium falciparum FCK2 in human erythrocyte culture after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID404934 | Antibacterial activity against methicillin-resistant Staphylococcus aureus by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID278480 | Antibacterial activity against Pneumococcus DAW9 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID1870145 | Antibacterial activity against wild type Staphylococcus aureus 4880/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID1870146 | Antibacterial activity against wild type Staphylococcus aureus 4460/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID575100 | Antimicrobial activity against Streptococcus pneumoniae serotype 22F assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID565742 | Antimicrobial activity against Streptococcus agalactiae clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID369232 | Antibacterial activity against inducible macrolide-lincosamide-streptogramin B-resistant Streptococcus pneumoniae isolates by double-disk diffusion method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID765063 | Antimicrobial activity against methicillin-sensitive Staphylococcus aureus 8325-4 by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. |
| AID535638 | Antimicrobial activity against Group B streptococcus serotype VI R2 harboring F395L, V405A, R433H, H438Y, and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID322787 | Antimicrobial activity against Bacteroides uniformis assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID520399 | Antibacterial activity against mef and erm(B) positive Streptococcus pneumoniae isolates assessed as resistance incidence by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). |
| AID511429 | Antimicrobial activity against Clostridium perfringens LFM1 assessed as susceptibility breakpoint by DIN-standardized microdilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Resistance to linezolid in a porcine Clostridium perfringens strain carrying a mutation in the rplD gene encoding the ribosomal protein L4. |
| AID534467 | Antimicrobial activity against carbapenemase-producing Bacteroides fragilis GAI 30144 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID278672 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 5733 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID574734 | Antimicrobial activity against Fusobacterium necrogenes after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID425967 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3274 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID404953 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus sp. assessed as percent resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID372461 | Antimalarial activity as 2nd generation ring-stage chloroquine-sensitive Plasmodium falciparum 3D7 after 48 hrs by flow cytometry | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID323013 | Antibacterial activity against drug-resistant Propionibacterium acnes P:413 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID423273 | Antibacterial activity against azithromycin-tolerant 0.01 MOI Chlamydia trachomatis L2AZM#23 harboring mutation in bacterial ribosomal protein L4 infected in mouse L2 cells treated 2 hrs after infection measured on day 7 by plaque assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2. |
| AID574500 | Antimicrobial activity against Bacteroides thetaiotaomicron assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID534338 | Antimicrobial activity against Burkholderia pseudomallei Bp250 harboring mini-Tn7T-bpeA+B+ -oprB+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID278484 | Antibacterial activity against Pneumococcus DAW15 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID575101 | Antimicrobial activity against Streptococcus pneumoniae serotype 23B assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID670948 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 at 2 ug/ml after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. |
| AID555300 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID323028 | Antibacterial activity against Corynebacterium amycolatum after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID278868 | Decrease in lactate production in MG63 cells by ELISA | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID561726 | Antibacterial activity against Enterococcus faecalis assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID41410 | In vitro antibacterial activity against the anaerobic Bacteroides melaninogenicus (Strain UC no.6326) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID372496 | Antimalarial activity in chloroquine-sensitive ACP1-GFP-labeled Plasmodium falciparum 3D7 after 48 hrs at 2xIC50 dosed 96 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID534455 | Antimicrobial activity against Lactobacillus casei subsp. casei JCM 1134 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID128550 | Bioactivity in blood, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 120 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID583895 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus isolate 453 (NRS23) by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID508475 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 237 harboring mutation in L4 ribosomal protein after 43 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID495941 | Antimicrobial activity against erythromycin resistant Staphylococcus haemolyticus isolate 202BB harboring msrA gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID535023 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-22 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID422645 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3676 after 14 passages with Telithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID522132 | Antimicrobial activity against Bacteroides thetaiotaomicron under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID596016 | Antiparasitic activity against green fluorescent protein expressing hwgprt deficient Toxoplasma gondii RH infected in HFF assessed as reduction of ycf24/UPRT genes copy number ratio at 1 uM treated for 48 hrs immediately after infection followed by reinoc | 2011 | Journal of medicinal chemistry, Apr-28, Volume: 54, Issue:8 | Chemistry and biology of macrolide antiparasitic agents. |
| AID547544 | Antimicrobial activity against invasive Streptococcus constellatus obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID1879574 | Antibacterial activity against Prevotella disiens MMX 3446 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID508456 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2368 harboring erm(B) gene after 6 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID129546 | In vivo antibacterial activity against Plasmodium berghei infected mice (Mus musculus) after subcutaneous administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID565076 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Pharmacodynamic profile of tigecycline against methicillin-resistant Staphylococcus aureus in an experimental pneumonia model. |
| AID278493 | Antibacterial activity against Pneumococcus DAW61 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID508400 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 24 harboring erm(B) gene after 14 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID524899 | Antibacterial activity against inducible macrolide-lincosamide-streptogramin B resistant erm(B) and mef(E)-positive Streptococcus pneumoniae by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. |
| AID428294 | Antimicrobial activity against Acinetobacter baumannii BM4652 expressing adeIJK genes with pAT807 isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID285158 | Antimicrobial susceptibility of tetracycline-resistant Streptococcus pneumoniae from respiratory tract disease patient assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland. |
| AID278578 | Decrease in Plasmodium falciparum FCK2 in erythrocytes at 5 uM after 84 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID768034 | Antibacterial activity against Listeria monocytogenes ATCC 19115 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID557460 | Antimicrobial activity in Prevotella corporis by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID424324 | Antimicrobial activity against Dialister micraerophilus assessed as susceptibility breakpoint by CA-SFM method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID495946 | Antimicrobial activity against erythromycin, lincomycin, clindamycin resistant Staphylococcus epidermidis isolate 32OL harboring msrA lnuA vgaALC gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID323024 | MBC/MIC ratio of Propionibacterium acnes SW101T | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID206815 | In vitro antibacterial activity against the aerobic Staphylococcus pyogenes (Strain UC no.152) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID562585 | Antimicrobial activity against erythromycin-susceptible Streptococcus agalactiae clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID327748 | Antibacterial activity against Enterococcus faecium by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Novel antibacterial azetidine lincosamides. |
| AID525144 | Antimicrobial activity against Staphylococcus epidermidis isolate 426-3147L expressing cfr gene by broth microdilution CLSI method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States. |
| AID574544 | Activity of Quorum sensing agr in community-associated methicillin-resistant Staphylococcus aureus USA300 assessed as PSMbeta expression after 8 hrs by qRT-PCR | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID322780 | Antimicrobial activity against Bacteroides eggerthii isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID41114 | In vitro antibacterial activity against the anaerobic Bacteroides distasonis (Strain UC no.6518) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID342062 | Antimicrobial activity against nonepidemic Clostridium difficile ATCC 9689 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID574033 | Antibacterial activity against beta-lactamase producing Micromonas micros assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID1459980 | In vivo antiparasitic activity against Plasmodium sp. assessed as parasite clearance time | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Comprehensive review on various strategies for antimalarial drug discovery. |
| AID444052 | Hepatic clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID574004 | Antibacterial activity against beta-lactamase producing Clostridium paraputrificum assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID545057 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate SZ009 from patient pus by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID534469 | Antimicrobial activity against Parabacteroides distasonis ATCC 8503 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID433369 | Antibacterial activity against Peptoniphilus asaccharolyticus isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID545053 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ372 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID206894 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.571) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID206897 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6687) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID51002 | Minimum inhibitory concentration against Clostridium perfringens ATCC 13124 | 1989 | Journal of medicinal chemistry, May, Volume: 32, Issue:5 | Aromatic dienoyl tetramic acids. Novel antibacterial agents with activity against anaerobes and staphylococci. |
| AID1879563 | Antibacterial activity against Mobiluncus curtisii subsp. curtisii ATCC 35241 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID531511 | Antibacterial activity against Bacteroides merdae assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID547526 | Antimicrobial activity against Streptococcus constellatus obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of 5% defr | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID278477 | Antibacterial activity against Pneumococcus DAW2 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID532676 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates assessed as susceptible isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID422644 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3676 after 44 passages with clarithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID585878 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 2 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID433200 | Antibacterial activity against Bacteroides ovatus isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID278492 | Antibacterial activity against Pneumococcus DAW57 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID279192 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolates from skin or soft tissue infection outpatients | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Treatment and outcomes of infections by methicillin-resistant Staphylococcus aureus at an ambulatory clinic. |
| AID625286 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID157247 | In vitro activity against Peptococcus magnus (ATCC 29328) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID285353 | Decrease in Panton-Valentine leukocidin level in community acquired methicillin-resistant Staphylococcus aureus HT20010734 in CYY medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID433004 | Antibacterial activity against Corynebacterium urealyticum isolated from patient with diabetic foot infection after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID508411 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 1635 harboring erm(A) gene after 32 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID323015 | Antibacterial activity against drug-resistant Propionibacterium acnes P322:2 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID128553 | Bioactivity in blood, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 30 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID1870158 | Antibacterial activity against wild type Staphylococcus aureus 4788/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID157248 | In vitro antibacterial activity against the anaerobic Peptococcus magnus(Strain UC no.6258) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID433196 | Antibacterial activity against Streptococcus dysgalactiae subsp. equisimilis isolated from patient with diabetic foot infection assessed as percent resistant isolates after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID495940 | Antimicrobial activity against lincomycin resistant Staphylococcus epidermidis isolate 102OL harboring lnuA gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID575078 | Antimicrobial activity against Streptococcus pneumoniae serotype 35B assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID535005 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus assessed as resistant isolates by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID555507 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis 197 after 50 passages by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID533412 | Antimicrobial activity against Finegoldia magna assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID586045 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type 1 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID561238 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as susceptible isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID528708 | Antibacterial activity against multidrug-resistant Streptococcus pneumoniae clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID574034 | Antibacterial activity against beta-lactamase producing Micromonas micros assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID396027 | Antibacterial activity against drug-resistant Enterobacter cloacae EcDC64 isolate expressing AcrAB-TolC efflux pump in presence of 20 ug/ml efflux pump inhibitor Phe-Arg-beta-naphthylamide by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID278668 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 2530 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID562938 | Upregulation of cwp84 gene expression in Clostridium difficile 6269 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID534447 | Antimicrobial activity against Bifidobacterium breve ATCC 15700 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID575147 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus VRS1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. |
| AID422670 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1076 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID322773 | Antimicrobial activity against Bacteroides fragilis isolates by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID508439 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 3009 harboring mutation in 23S rRNA after 50 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID574991 | Antimicrobial activity against Bifidobacterium adolescentis assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID129544 | In vivo antibacterial activity against Pasteurella multocida (UC no 264) infected mice after sc administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID562604 | Antimicrobial activity against oxacillin-susceptible Staphylococcus aureus clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID574506 | Antimicrobial activity against Bacteroides distasonis assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID558004 | Antimicrobial activity in Clostridium hastiforme by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID528969 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID422658 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1077 after 49 passages with clindamycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID1079942 | Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source] | |||
| AID541032 | Antiproliferative activity against Theileria parva-induced proliferation of bovine B lymphocyte assessed as inhibition of [3H]thymidine uptake after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Theileria apicoplast as a target for chemotherapy. |
| AID285351 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20041010 in CCY media | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID322991 | Antibacterial activity against drug-resistant Propionibacterium acnes SW17 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID516161 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolates assessed as resistant isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID768035 | Antibacterial activity against Bacillus subtilis 168 harboring AAC(6')/APH(2'')-pRB374 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID41269 | Minimum inhibitory concentration against Bacteroides fragilis ATCC 25285 | 1989 | Journal of medicinal chemistry, May, Volume: 32, Issue:5 | Aromatic dienoyl tetramic acids. Novel antibacterial agents with activity against anaerobes and staphylococci. |
| AID425987 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3243 after 33 passages with azithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID41258 | In vitro antibacterial activity against the anaerobic Bacteroides fragilis (Strain UC no.6864) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID342097 | Increase in toxin level in nonepidemic Clostridium difficile J29 infected CF1 mouse at 1.4 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID160397 | In vitro antibacterial activity against the anaerobic Propionibacterium acnes(Strain UC no.6575) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID129545 | In vivo antibacterial activity against Pasteurella multocida(UC 264) infected mice after oral administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID459266 | Antimicrobial activity against Toxoplasma gondii RH infected in BALB/c mouse assessed as mouse survival at 50 mg/kg, ip after 5 days | 2010 | Bioorganic & medicinal chemistry, Feb-15, Volume: 18, Issue:4 | CoMFA analysis of tgDHFR and rlDHFR based on antifolates with 6-5 fused ring system using the all-orientation search (AOS) routine and a modified cross-validated r(2)-guided region selection (q(2)-GRS) routine and its initial application. |
| AID541029 | Induction of apoptosis in bovine BL3 cells assessed as viable cells after 24 hrs by annexin V/propidium iodide staining-based FACS analysis | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Theileria apicoplast as a target for chemotherapy. |
| AID422690 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3413 after 30 passages with Telithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID425988 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3243 after 29 passages with Telithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID588212 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID562603 | Antimicrobial activity against oxacillin-resistant Staphylococcus aureus clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID497970 | Antimicrobial activity against Staphylococcus aureus infection in human assessed as curing from bone/joint infection at 600 mg, iv followed by 30 to 40 mg/kg of body weight, iv followed by oral regimen upto 30 months | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Continuous clindamycin infusion, an innovative approach to treating bone and joint infections. |
| AID342092 | Increase in toxin level in nonepidemic Clostridium difficile ATCC 9689 infected in CF1 mouse at 2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID561235 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID535632 | Antimicrobial activity against Group B streptococcus R8 harboring T77I, S353F and A514V in PBP 2X; V80A and G613R in PBP 2B; and L45P, N163K, N723S and G527V in PBP 1A by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID534449 | Antimicrobial activity against Bifidobacterium pseudolongum ATCC 25526 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID583889 | Antibacterial activity against hospital-associated methicillin-resistant Staphylococcus aureus isolate 360 by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID50733 | In vitro activity against Clostridium difficile (ATCC 17857) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID1625272 | Antimalarial activity against Plasmodium falciparum 3D7 after 48 hrs | 2016 | Journal of medicinal chemistry, 06-23, Volume: 59, Issue:12 | Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action. |
| AID396030 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pAP2 plasmid containing Enterobacter cloacae acrA gene by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID532678 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates assessed as resistant isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID342065 | Antimicrobial activity against epidemic Clostridium difficile BI6-8-17 by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID342260 | Inhibition of clindamycin-susceptible nonepidemic Clostridium difficile strain6 in CF1 mouse at 0.2 mg/day, sc for 5 days | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID545048 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ210 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID520289 | Antimicrobial activity against Staphylococcus aureus 2546 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Activities of daptomycin and comparative antimicrobials, singly and in combination, against extracellular and intracellular Staphylococcus aureus and its stable small-colony variant in human monocyte-derived macrophages and in broth. |
| AID522169 | Antimicrobial activity against Anaerococcus vaginalis under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID548739 | Antimicrobial activity against Oxacillin-susceptible coagulase-negative Staphylococcus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1870157 | Antibacterial activity against wild type Staphylococcus aureus 5079/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID323034 | Antibacterial activity against Streptococcus dysgalactiae subsp. dysgalactiae after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1870148 | Antibacterial activity against wild type Staphylococcus aureus 4566/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID554554 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MAB30 preincubated with 2 ug/ml erythromycin for 20 to 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID562581 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus pyogenes clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID542387 | Antimicrobial activity against Staphylococcus aureus RN4220 | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID433199 | Antibacterial activity against Bacteroides caccae isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID278584 | Reduced apicoplast genome copy number in Plasmodium falciparum FCK2 after 96 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID574026 | Antibacterial activity against beta-lactamase producing Peptostreptococcus anaerobius assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID1879568 | Antibacterial activity against Peptostreptococcus anaerobius ATCC 27337 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID529870 | Antimicrobial activity against Escherichia coli AG100A harboring pAT392 containing mph(B) and rdmC-like genes by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID586048 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type U1 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID717272 | Antimicrobial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 by CLSI protocol based broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. |
| AID285355 | Decrease in Panton-Valentine leukocidin level in community acquired methicillin-resistant Staphylococcus aureus HT20030203 in CYY medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID574526 | Antimicrobial activity against Prevotella intermedia assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID530123 | Antimicrobial activity against hospital acquired methicillin-resistant Staphylococcus aureus 56 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. |
| AID574983 | Antimicrobial activity against Actinomyces naeslundii assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID574979 | Antimicrobial activity against Actinomyces meyeri assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID535034 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-126 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID72260 | In vitro activity against Fusobacterium sp.(GS-10) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID322788 | Antimicrobial activity against Bacteroides vulgatus assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID574726 | Antimicrobial activity against Prevotella oralis assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID516166 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus clinical isolates assessed as susceptible isolates by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates. |
| AID581658 | Cmax in human plasma | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID278669 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 2514 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID1879570 | Antibacterial activity against Prevotella bivia ATCC 29303/MMX 5718 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID425984 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1635 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID278506 | Antibacterial activity against Pneumococcus CDC023 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID534458 | Antimicrobial activity against Lactobacillus reuteri JCM 1112 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID433367 | Antibacterial activity against Anaerococcus tetradius isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID555312 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 after 50 passages by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID625289 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID508389 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 1077 after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID531566 | Antibacterial activity against Enterococcus faecium obtained from complicated skin and skin structure infections by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. |
| AID285349 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20030203 in CCY media | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID554546 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC958 preincubated with 2 ug/ml erythromycin for 20 to 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID1698700 | Antibacterial activity against Bacteroides fragilis ATCC 25285 by CLSI method | 2020 | Bioorganic & medicinal chemistry, 11-15, Volume: 28, Issue:22 | Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors. |
| AID424423 | Antibacterial activity against Enterococcus faecalis HIP15179 coisolated with vancomycin-resistant Staphylococcus aureus by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID524897 | Antibacterial activity against inducible macrolide-lincosamide-streptogramin B resistant and erm(B)-positive Streptococcus pneumoniae by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. |
| AID562930 | Antimicrobial activity against Clostridium difficile CD07-259 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID522195 | Antimicrobial activity against Clostridium ramosum under anaerobic conditions after 44 hrs by CLSI-M11-47 protocol based agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. |
| AID1909751 | Toxicity in Balb/c mouse infected with methicillin-resistant Staphylococcus aureus USA300 assessed as necrosis at 25 mg/kg, ip administered 2 days post infection twice daily and measured after 5 days post compound treatment by H and E staining based histo | 2022 | Journal of medicinal chemistry, 05-12, Volume: 65, Issue:9 | Mechanistic Studies and |
| AID535035 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-402 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID41562 | In vitro activity against Bacteroides vulgatus(SFBC 2375) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID554543 | Antimicrobial activity against Mycobacterium smegmatis transformed with erm allele Mycobacterium abscessus isolate MC719 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID200522 | In vitro antibacterial activity against the aerobic Salmonella schottmuelleri (Strain UC no.126) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID535022 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-19 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID50843 | In vitro antibacterial activity against the anaerobic Clostridium difficile (Strain UC no.6834) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID528701 | Antibacterial activity against Streptococcus viridans clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID528835 | Antimicrobial activity against vancomycin-resistant Enterococcus sp. isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID555309 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis 197 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID574772 | Antimicrobial activity against Clostridium perfringens assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID285352 | Decrease in Panton-Valentine leukocidin level in Staphylococcus aureus LUG855 in CCY medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID278508 | Antibacterial activity against Pneumococcus CDC063 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID424421 | Antibacterial activity against Enterococcus faecalis HIP14333 isolated from patients rectum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID562413 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus Group C clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID562935 | Upregulation of slpA gene expression in Clostridium difficile 6269 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID535640 | Antimicrobial activity against Group B streptococcus serotype Ib C2 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID555301 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus 505 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID41255 | In vitro antibacterial activity against the anaerobic Bacteroides fragilis (Strain UC no.6428) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID561240 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID422674 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3009 after 21 passages with gemifloxacin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID41437 | Minimum inhibitory concentration against Bacteroides thetaiotaomicron ATCC 29741 | 1989 | Journal of medicinal chemistry, May, Volume: 32, Issue:5 | Aromatic dienoyl tetramic acids. Novel antibacterial agents with activity against anaerobes and staphylococci. |
| AID71072 | In vitro antibacterial activity against the aerobic Escherichia coli (Strain UC no.45) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID562390 | Antimicrobial activity against oxacillin-resistant Staphylococcus haemolyticus clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID588211 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID497968 | Cmax po dosed in human co-treated with rifampin | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Continuous clindamycin infusion, an innovative approach to treating bone and joint infections. |
| AID369229 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae assessed as percent resistant isolates by CLSI breakpoint method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID423265 | Antibacterial activity against 0.01 MOI wild type Chlamydia psittaci 6BC BCRB infected in mouse L2 cells treated 2 hrs after infection measured on day 7 by plaque assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2. |
| AID625283 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID585168 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA G2032A mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID342091 | Effect on growth of epidemic Clostridium difficile BI6-8-17 in CF1 mouse assessed as increase in bacterial density in cecal content at 1.4 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID581663 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient infected in human THP-1 cells assessed as log reduction of intracellular CFU level per mg of protein at up to 10'5 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID372479 | Antimalarial activity as segregation of apicoplast in chloroquine-sensitive ACP1-GFP-labeled Plasmodium falciparum 3D7 schizont infected human erythrocytes at 25 nM dosed 96 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID549014 | Antimicrobial activity against Beta-hemolytic Streptococcus assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID574760 | Antimicrobial activity against Peptoniphilus asaccharolyticus assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID422680 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3009 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID574006 | Antibacterial activity against beta-lactamase producing Clostridium tertium assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID425098 | Antimicrobial activity against Anaerococcus prevotii isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID545042 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ043 from patient abdominal drainage by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID404951 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus sp. assessed as percent resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID508432 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 7127 harboring S20N mutation in L4 ribosomal protein and A105V mutation in L22 ribosomal protein after 38 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID586047 | Antimicrobial activity against Staphylococcus aureus clone 3-3 harboring staphylococcal cassette chromosome mec element type 6 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID508444 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 7127 harboring S20N mutation in L4 ribosomal protein and A105V mutation in L22 ribosomal protein after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID573574 | Antibacterial activity against beta-lactamase producing Bacteroides uniformis assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID125733 | Bioactivity in abscess, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 15 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID372464 | Antimalarial activity as 3rd generation ring-stage chloroquine-resistant Plasmodium falciparum W2 after 48 hrs dose then 48 hrs drug-free | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID342088 | Effect on growth of nonepidemic Clostridium difficile ATCC 9689 in CF1 mouse assessed as increase in bacterial density in cecal content at 1.4 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID372463 | Antimalarial activity as 2nd generation ring-stage chloroquine-resistant Plasmodium falciparum W2 after 48 hrs by flow cytometry | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID528967 | Antimicrobial activity against methicillin-susceptible Staphylococcus epidermidis isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID520741 | Antimicrobial activity against cfr-deficient Staphylococcus aureus RN4220 harboring erm(B) gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. |
| AID425111 | Antimicrobial activity against beta lactamase-positive Bacteroides thetaiotaomicron isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID50860 | In vitro antibacterial activity against the anaerobic Clostridium novyi B(Strain UC no.6329) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID555303 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 145 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID534431 | Antimicrobial activity against Peptoniphilus asaccharolyticus WAL 3218 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID586051 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type 1 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID278581 | Reduction in Plasmodium falciparum FCK2 in human blood cell culture after 96 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID533130 | Antimicrobial activity against Bacteroides distasonis assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID425979 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1635 after 49 passages with clarithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID285345 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20041010 in Mueller-Hinton medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID323036 | Antibacterial activity against Streptococcus pyogenes after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID125732 | Bioactivity in abscess, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 120 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID533665 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID534439 | Antimicrobial activity against Clostridium difficile GAI 10029 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID519481 | Antibacterial activity against Staphylococcus aureus T991 by Etest method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances. |
| AID571767 | Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-615-628MexB-M626I mutant gene | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID585167 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA G2032A, C2499A mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID562395 | Antimicrobial activity against Staphylococcus epidermidis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID573582 | Antibacterial activity against beta-lactamase producing Bacteroides caccae assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID508438 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 3009 harboring mutation in 23S rRNA after 25 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID424322 | Antimicrobial activity against Dialister micraerophilus assessed as susceptibility breakpoint by CLSI method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID1870143 | Antibacterial activity against wild type Staphylococcus aureus 4862/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID342094 | Increase in toxin level in epidemic Clostridium difficile BI9 infected CF1 mouse at 2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID508440 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 3665 harboring mef(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID562927 | Antimicrobial activity against Clostridium difficile ATCC 43603-M1 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID529878 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring empty vector by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID206904 | In vitro antibacterial activity against the aerobic Staphylococcus aureus (Strain UC no.6694) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID585162 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA G2505A mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID508412 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 1635 harboring erm(A) gene after 14 passages following overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID541027 | Antiproliferative activity against Theileria parva-induced proliferation of bovine BL3 cells assessed as inhibition of [3H]thymidine uptake after 32 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Theileria apicoplast as a target for chemotherapy. |
| AID424323 | Antimicrobial activity against Dialister pneumosintes assessed as susceptibility breakpoint by CA-SFM method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID584995 | Antibacterial activity against pSCFS7-deficient methicillin-resistant Staphylococcus aureus M05/0060-C1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Identification and characterization of the multidrug resistance gene cfr in a Panton-Valentine leukocidin-positive sequence type 8 methicillin-resistant Staphylococcus aureus IVa (USA300) isolate. |
| AID528845 | Antimicrobial activity against methicillin-resistant Staphylococcus epidermidis isolated from ICU patient wound assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID561255 | Antibacterial activity against Streptococcus pyogenes assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID524826 | Antibacterial activity against erythromycin resistant Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID533634 | Antimicrobial activity against Propionibacterium acnes assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID573795 | Antibacterial activity against Prevotella buccae assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID404899 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB34 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID548471 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID1879554 | Antibacterial activity against metronidazole-resistant Bacteroides ovatus MMX 3504 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID1879562 | Antibacterial activity against Gardnerella vaginalis ATCC 49145 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID444050 | Fraction unbound in human plasma | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID425972 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 2527 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID283555 | Antimicrobial activity against Streptococcus pneumoniae R6 transformants | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID278496 | Antibacterial activity against Pneumococcus DAW66 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID694206 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 by CLSI broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 22, Issue:22 | Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. |
| AID278583 | Reduced apicoplast genome copy number in Plasmodium falciparum FCK2 after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. |
| AID283551 | Antimicrobial activity against Streptococcus pneumoniae PC13 transformants | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID586042 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type U3 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID588213 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID535031 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-74 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID129542 | In vivo antibacterial activity against Klebsiella pneumoniae (UC 58) infected mice after sc administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID581670 | Antibacterial activity against Staphylococcus aureus SCV isolated from cystic fibrosis patient in cation-adjusted MH 2 broth at pH 5.5 after 48 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID433197 | Antibacterial activity against Streptococcus pyogenes isolated from patient with diabetic foot infection assessed as percent resistant isolates after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID557651 | Antimicrobial activity against Mycobacterium abscessus isolate MC879 at day 7 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. |
| AID404949 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate assessed as percent resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID548256 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID534478 | Antimicrobial activity against Prevotella buccae ATCC 33574 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID574504 | Antimicrobial activity against Bacteroides caccae assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID372467 | Antimalarial activity as segregation of apicoplasts against chloroquine-sensitive Plasmodium falciparum 3D7 infected human erythrocytes at 25 nM 96 hrs post infection | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast. |
| AID625280 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID562377 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus agalactiae clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID547527 | Antimicrobial activity against Streptococcus constellatus obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on brain heart infusion agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID285162 | Antimicrobial activity against non replicating persistence Mycobacterium tuberculosis H37Rv in anaerobic condition assessed as bacterial density after 10 days | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. |
| AID322989 | Antibacterial activity against drug-resistant Propionibacterium acnes SW10 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID323032 | Antibacterial activity against methicillin-resistant Staphylococcus aureus after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID528840 | Antimicrobial activity against penicillin-resistant Streptococcus pneumoniae isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID561248 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis assessed as resistant isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID547754 | Antimicrobial activity against invasive Streptococcus constellatus obtained from non-cystic fibrosis patient assessed as non-susceptible isolates grown on brain heart infusion agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID585161 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA A2503G mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID51137 | In vitro antibacterial activity against the anaerobic Clostridium sordellii (Strain UC no.6505) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID555505 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis 057 after 10 passages by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID768029 | Antibacterial activity against Escherichia coli MC1061 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID535636 | Antimicrobial activity against Group B streptococcus serotype VI R4 harboring Q557E mutation in PBP 2X and T567I, Y262N mutations in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID625279 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID573557 | Antibacterial activity against beta-lactamase producing Bacteroides thetaiotaomicron assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID562404 | Antimicrobial activity against penicillin-susceptible Streptococcus pneumoniae clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID574510 | Antimicrobial activity against Bacteroides vulgatus assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID425964 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3274 after 48 passages with Telithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID508430 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 7127 harboring S20N mutation in L4 ribosomal protein and A105V mutation in L22 ribosomal protein after 15 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID423267 | Antibacterial activity against azithromycin-resistant 0.01 MOI Chlamydia psittaci 6BC BCRBAZ5 harboring A2059C mutation in bacterial 23S rRNA gene infected in mouse L2 cells treated 2 hrs after infection measured on day 7 by plaque assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2. |
| AID535029 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-68 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID128556 | Bioactivity in blood, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 60 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID533396 | Antimicrobial activity against Clostridium innocuum assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID540211 | Fraction unbound in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID574967 | Antimicrobial activity against Actinomyces odontolyticus assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID424328 | Antimicrobial activity against Dialister invisus by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID575003 | Antimicrobial activity against Eubacterium lentum assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID588220 | Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset | 2008 | Toxicology mechanisms and methods, , Volume: 18, Issue:2-3 | Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. |
| AID574042 | Antibacterial activity against beta-lactamase producing Peptoniphilus asaccharolyticus assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID520736 | Antimicrobial activity against erm(B) and cfr-deficient Staphylococcus aureus RN4220 harboring plasmid LI50 by disk diffusion assay | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. |
| AID323033 | Antibacterial activity against borderline oxacillin-resistant Staphylococcus aureus after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID562597 | Antimicrobial activity against oxacillin-resistant Staphylococcus haemolyticus clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID533134 | Antimicrobial activity against Bacteroides fragilis assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID541028 | Induction of apoptosis in bovine BL3 cells assessed as early apoptotic cells after 24 hrs by annexin V/propidium iodide staining-based FACS analysis | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Theileria apicoplast as a target for chemotherapy. |
| AID508453 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2368 harboring erm(B) gene after 8 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID528966 | Antimicrobial activity against methicillin-susceptible Staphylococcus epidermidis isolated from ICU patient urine assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID285343 | Antibacterial activity against community acquired methicillin-resistant Staphylococcus aureus HT20030203 in Mueller-Hinton medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID129554 | In vivo antibacterial activity against Streptococcus pneumoniae IIII(UC 3213) infected mice after sc administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID508442 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 1635 harboring erm(A) gene after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID342246 | Increase in toxin level in epidemic Clostridium difficile BI6-8-17 infected CF1 mouse at 0.2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID425968 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 2527 after 14 passages with gemifloxacin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID279193 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus isolates from skin or soft tissue infection outpatients | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Treatment and outcomes of infections by methicillin-resistant Staphylococcus aureus at an ambulatory clinic. |
| AID444058 | Volume of distribution at steady state in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID529869 | Antimicrobial activity against Escherichia coli AG100A harboring pAT392 containing mph(B) gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. |
| AID278483 | Antibacterial activity against Pneumococcus DAW14 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID562929 | Antimicrobial activity against Clostridium difficile CD196 M1 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID557690 | Antimicrobial activity in Prevotella bergensis by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID396031 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pACYC184 plasmid by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID278502 | Antibacterial activity against Pneumococcus CDC001 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID549015 | Antimicrobial activity against viridans group Streptococcus assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID561736 | Antibacterial activity against Beta-hemolytic Streptococcus group B assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID129541 | In vivo antibacterial activity against Escherichia coli(UC 311) infected mice after oral administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID369233 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae isolates by double-disk diffusion method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Serotypes, Clones, and Mechanisms of Resistance of Erythromycin-Resistant Streptococcus pneumoniae Isolates Collected in Spain. |
| AID508445 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 3009 harboring mutation in 23S rRNA after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID561259 | Antibacterial activity against Streptococcus agalactiae assessed as intermediate isolates by CLSI M100-S17 method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity. |
| AID342261 | Inhibition of clindamycin-susceptible epidemic Clostridium difficile NAP1 in CF1 mouse at 0.2 mg/day, sc for 5 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID583896 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus isolate 454 (NRS404) by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID562598 | Antimicrobial activity against oxacillin-susceptible Staphylococcus haemolyticus clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID533664 | Antimicrobial activity against Staphylococcus aureus RN1024-tms | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID323011 | Antibacterial activity against drug-resistant Propionibacterium acnes SP64E after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID575076 | Antimicrobial activity against Streptococcus pneumoniae serotype 19A assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID581657 | Antibacterial activity against normal phenotype Staphylococcus aureus at pH 7.4 after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID584996 | Antibacterial activity against methicillin-resistant Staphylococcus aureus M05/0060 harboring cfr-encoding conjugative pSCFS7 and fexA by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Identification and characterization of the multidrug resistance gene cfr in a Panton-Valentine leukocidin-positive sequence type 8 methicillin-resistant Staphylococcus aureus IVa (USA300) isolate. |
| AID444054 | Oral bioavailability in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID1870140 | Antibacterial activity against wild type Staphylococcus aureus 4557/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID1879567 | Antibacterial activity against Peptostreptococcus magnus ATCC 14956 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID278507 | Antibacterial activity against Pneumococcus CDC050 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID533661 | Antimicrobial activity against Staphylococcus aureus RN4220 harboring plasmid CU1 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID571766 | Antimicrobial activity against Escherichia coli K-12 3-AG300 harboring AcrB-615-628MexB-N616 mutant gene | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. |
| AID575001 | Antimicrobial activity against Eubacterium lentum assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID560248 | Antibacterial activity against Staphylococcus aureus RN4220 harboring aadD, tet(L), dfrK and vga(C) gene by CLSI method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID573837 | Antibacterial activity against beta-lactamase producing Clostridium tertium assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID128551 | Bioactivity in blood, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 15 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID428290 | Antimicrobial activity against Acinetobacter baumannii BM4454 isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID533384 | Antimicrobial activity against Bacteroides nordii assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID425716 | Antimicrobial activity against Balamuthia mandrillaris ATCC 50209 infected in HBMEC assessed as inhibition of encystment at 5 ug/mL after 7 days | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity. |
| AID322783 | Antimicrobial activity against Bacteroides fragilis assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID433178 | Antibacterial activity against Proteus vulgaris isolated from patient with diabetic foot infection assessed as percent resistant isolates after 18 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID535036 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-403 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID129555 | In vivo antibacterial activity against Streptococcus pyogenes(UC 152) infected mice after oral administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID584122 | Antimicrobial activity against Staphylococcus aureus RN4220 by CLSI M31-A3 method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. |
| AID524894 | Antibacterial activity against macrolide resistant and mef(E)-positive Streptococcus pneumoniae by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. |
| AID533380 | Antimicrobial activity against Bacteroides merdae assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID1625273 | Antimalarial activity against Plasmodium falciparum 3D7 after 96 hrs | 2016 | Journal of medicinal chemistry, 06-23, Volume: 59, Issue:12 | Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action. |
| AID320706 | Inhibition of PAD4 by ABPP-based assay | 2008 | Bioorganic & medicinal chemistry, Jan-15, Volume: 16, Issue:2 | Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors. |
| AID278479 | Antibacterial activity against Pneumococcus DAW8 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID561747 | Antibacterial activity against Methicillin-resistant Staphylococcus aureus assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID283658 | Antimicrobial activity against Haemophilus influenzae NB65044 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Reduced susceptibility of Haemophilus influenzae to the peptide deformylase inhibitor LBM415 can result from target protein overexpression due to amplified chromosomal def gene copy number. |
| AID425722 | Antimicrobial activity against Balamuthia mandrillaris ATCC 50209 infected in HBMEC assessed as inhibition of amoeba-induced cytopathogenicity at 5 ug/mL after 24 hrs by LDH release assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity. |
| AID322784 | Antimicrobial activity against Bacteroides distasonis assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID342262 | Inhibition of clindamycin-susceptible nonepidemic Clostridium difficile strain6 in CF1 mouse at 0.2 mg/day, sc for 5 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID323001 | Antibacterial activity against drug-resistant Propionibacterium acnes P95 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID425995 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3676 after 50 passages with moxifloxacin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID533420 | Antimicrobial activity against Micromonas micros assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID535019 | Antimicrobial activity against vancomycin intermediate Staphylococcus aureus NRS-4 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID574732 | Antimicrobial activity against Fusobacterium varium after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID528709 | Antibacterial activity against penicillin resistant Streptococcus pneumoniae clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID535647 | Antimicrobial activity against Group B Streptococcus serotype V 2603 V/R harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID555742 | Antibacterial activity against methicillin-resistant, Linezolid non-susceptible coagulase-negative Staphylococcus epidermidis 345 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID342085 | Effect on growth of nonepidemic Clostridium difficile J29 in CF1 mouse assessed as increase in bacterial density in cecal content at 2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID342243 | Increase in toxin level in nonepidemic Clostridium difficile ATCC 9689 infected in CF1 mouse at 0.2 mg/day, sc for 4 days assessed after 2 days of last treatment | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Effect of fluoroquinolone treatment on growth of and toxin production by epidemic and nonepidemic clostridium difficile strains in the cecal contents of mice. |
| AID41257 | In vitro antibacterial activity against the anaerobic Bacteroides fragilis (Strain UC no.6862) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID495947 | Antimicrobial activity against Staphylococcus aureus isolate CIP 107907 harboring vgaA gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID535635 | Antimicrobial activity against Group B streptococcus serotype VI R5 harboring F395L, V405A, R433H, H438Y, and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID323002 | Antibacterial activity against drug-resistant Propionibacterium acnes P401:5 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID428138 | Antimicrobial activity against telithromycin-resistant Streptococcus pneumoniae isolate P1501016 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation. |
| AID524898 | Antibacterial activity against constitutive macrolide-lincosamide-streptogramin B resistant and erm(B)-positive Streptococcus pneumoniae by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. |
| AID433186 | Antibacterial activity against Corynebacterium striatum isolated from patient with diabetic foot infection assessed as percent resistant isolates after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID425985 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3243 after 20 passages with moxifloxacin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID562612 | Antimicrobial activity against penicillin-resistant Streptococcus pneumoniae clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID433359 | Antibacterial activity against Clostridium aminovalericum isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID562378 | Antimicrobial activity against erythromycin-susceptible Streptococcus agalactiae clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1879572 | Antibacterial activity against metronidazole-resistant Prevotella bivia MMX 3454 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID562368 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus Group G clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID574512 | Antimicrobial activity against Bacteroides vulgatus assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID433353 | Antibacterial activity against Parabacteroides distasonis isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID422666 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1076 after 35 passages with moxifloxacin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID520001 | Antimicrobial activity against Haemophilus influenzae | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID548746 | Antimicrobial activity against viridans group Streptococcus assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID562222 | Antimicrobial activity against Desulfovibrio desulfuricans Essex 6 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID422661 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 1077 after 15 passages with Telithromycin measured after 10 antibiotic-free subculture by multi-step resistance selection technique | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID396029 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate in presence of 20 ug/ml efflux pump inhibitor Phe-Arg-beta-naphthylamide by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID581656 | Antibacterial activity against revertant Staphylococcus aureus at pH 7.4 after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a |
| AID278876 | Antiproliferative effect against primary human osteoblasts in presence of 10% FCS | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID157243 | In vitro antibacterial activity against the anaerobic Peptococcus asaccharolyticus (Strain UC no.6214) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID534788 | Antimicrobial activity against community-acquired methicillin-resistant Staphylococcus aureus assessed as susceptible isolates by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID495938 | Antimicrobial activity against lincomycin, clindamycin resistant Staphylococcus haemolyticus isolate 29OL harboring vgaALC gene incubated at 37 degC for 24 hrs by agar diffusion method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci. |
| AID50726 | In vitro antibacterial activity against the anaerobic Clostridium bifermentans (Strain UC no.6507) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID562221 | Antimicrobial activity against Desulfovibrio fairfieldensis by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID323029 | Antibacterial activity against Corynebacterium minutissimum after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID433363 | Antibacterial activity against Clostridium malenominatum isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID50847 | In vitro antibacterial activity against the anaerobic Clostridium difficile (Strain UC no.6861) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID768026 | Antibacterial activity against biofilm negative Staphylococcus epidermidis ATCC 12228 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID278673 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 5734 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID574498 | Antimicrobial activity against Bacteroides thetaiotaomicron assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID41101 | In vitro activity against Bacteroides bivius(B 6140) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID765060 | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis ATCC 51575 by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. |
| AID327747 | Antibacterial activity against macrolide, licosamide and streptogramin resistant Staphylococcus aureus by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Novel antibacterial azetidine lincosamides. |
| AID588208 | Literature-mined public compounds from Lowe et al phospholipidosis modelling dataset | 2010 | Molecular pharmaceutics, Oct-04, Volume: 7, Issue:5 | Predicting phospholipidosis using machine learning. |
| AID625287 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID534344 | Antimicrobial activity against Burkholderia pseudomallei Bp174 harboring mini-Tn7T-bpeR+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID1459982 | In vivo antiparasitic activity against Babesia sp. assessed as parasite clearance time | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Comprehensive review on various strategies for antimalarial drug discovery. |
| AID1459984 | In vivo antiparasitic activity against Plasmodium sp. assessed as fever clearance time | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Comprehensive review on various strategies for antimalarial drug discovery. |
| AID545054 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ390 from patient secretion by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID278478 | Antibacterial activity against Pneumococcus DAW6 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID534473 | Antimicrobial activity against Bacteroides eggerthii ATCC 27754 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID575081 | Antimicrobial activity against Streptococcus pneumoniae serotype 6C assessed as percent susceptible isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. |
| AID768030 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID535259 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-7 expressing SCCmec element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID1459985 | In vivo antiparasitic activity against Toxoplasma sp. assessed as fever clearance time | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Comprehensive review on various strategies for antimalarial drug discovery. |
| AID41428 | In vitro activity against Bacteroides thetaiotaomicron (ATCC 29742) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID50991 | In vitro activity against Clostridium perfringens (788) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID555305 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus VRS1 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID508396 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 1077 after 15 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID508398 | Antibacterial activity against macrolide-susceptible Streptococcus pneumoniae 1077 after 49 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID545056 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate DL010 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID433198 | Antibacterial activity against Bacteroides fragilis isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID373750 | Antimicrobial activity against mupirocin-resistant methicillin-resistant Staphylococcus aureus assessed as resistant rate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals. |
| AID584993 | Antibacterial activity against Staphylococcus aureus XU21 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Identification and characterization of the multidrug resistance gene cfr in a Panton-Valentine leukocidin-positive sequence type 8 methicillin-resistant Staphylococcus aureus IVa (USA300) isolate. |
| AID1698701 | Antibacterial activity against Prevotella melaninogenica JCM6325 by CLSI method | 2020 | Bioorganic & medicinal chemistry, 11-15, Volume: 28, Issue:22 | Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors. |
| AID1079945 | Animal toxicity known. [column 'TOXIC' in source] | |||
| AID283553 | Antimicrobial activity against Streptococcus pneumoniae PC13 isolate with L4 mutation | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae. |
| AID534480 | Antimicrobial activity against Prevotella heparinolytica ATCC 35895 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID1879569 | Antibacterial activity against metronidazole-resistant Prevotella asaccharolytica MMX 3552 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID542386 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus ST9 expressing cfr, fexA and erm(C) genes | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID583886 | Antibacterial activity against community-associated methicillin-resistant Staphylococcus aureus isolate 156 by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID425106 | Antimicrobial activity against Clostridium clostridioforme isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID425109 | Antimicrobial activity against Clostridium cadaveris isolated from intra-abdominal infection and pelvic inflammatory disease patients after 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1 | Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis. |
| AID428292 | Antimicrobial activity against Acinetobacter baumannii BM4579 expressing deltaadeIJK genes isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID528972 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolated from ICU patient blood assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID433354 | Antibacterial activity against Parabacteroides merdae isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID531514 | Antibacterial activity against Bacteroides ovatus assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID557976 | Antimicrobial activity in Clostridium ramosum by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID428293 | Antimicrobial activity against Acinetobacter baumannii BM4651 expressing deltaadeIJK genes isolated from patient with urinary tract infection by E test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii. |
| AID585159 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA A2453U mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID561745 | Antibacterial activity against Methicillin-sensitive Staphylococcus aureus assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID535261 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-9 expressing SCCmec type 2 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID562610 | Antimicrobial activity against penicillin-intermediate Streptococcus pneumoniae clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID574748 | Antimicrobial activity against Peptostreptococcus micros assessed as percent susceptible isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID322789 | Antimicrobial activity against Bacteroides caccae assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID1870154 | Antibacterial activity against wild type Staphylococcus aureus 4679/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID555311 | Antibacterial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis 345 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID585172 | Antibacterial activity against Mycobacterium smegmatis harboring 23S rRNA C2055A mutant after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID1870149 | Antibacterial activity against wild type Staphylococcus aureus 4504/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID528710 | Antibacterial activity against penicillin intermediate Streptococcus pneumoniae clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID765061 | Antimicrobial activity against vancomycin-sensitive Enterococcus faecalis ATCC 19433 by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 23, Issue:17 | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. |
| AID425994 | Antimicrobial activity against drug-resistant Streptococcus pneumoniae isolate 3243 by NCCLS M7-A7 method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies. |
| AID557702 | Antimicrobial activity in Prevotella sp.by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID433351 | Antibacterial activity against Bacteroides uniformis isolated from patient with diabetic foot infection assessed as percent resistant isolates after 44 to 48 hrs by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID51131 | In vitro activity against Clostridium ramosum (7) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID586043 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type U5 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID528703 | Antibacterial activity against Streptococcus oralis clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID424327 | Antimicrobial activity against Dialister propionicifaciens by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Antimicrobial susceptibilities and clinical sources of Dialister species. |
| AID129549 | In vivo antibacterial activity against Staphylococcus aureus (UC no 76) infected mice after sc administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID1474167 | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring verified drug-induced liver injury concern status | 2016 | Drug discovery today, Apr, Volume: 21, Issue:4 | DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. |
| AID1459981 | In vivo antiparasitic activity against Toxoplasma sp. assessed as parasite clearance time | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Comprehensive review on various strategies for antimalarial drug discovery. |
| AID524896 | Antibacterial activity against macrolide resistant and mef-positive Streptococcus pneumoniae by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. |
| AID555306 | Antibacterial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis 051 by broth macrodilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs. |
| AID573801 | Antibacterial activity against Prevotella intermedia assessed as resistant isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID583884 | Antibacterial activity against hospital-associated methicillin-resistant Staphylococcus aureus isolate 152 by broth microdilution assay | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model. |
| AID323016 | Antibacterial activity against drug-resistant Propionibacterium acnes EG7NS after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID768028 | Antibacterial activity against Haemophilus influenzae ATCC 51907 by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID586040 | Antimicrobial activity against Staphylococcus aureus clone 2-2 harboring staphylococcal cassette chromosome mec element type 1 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID545043 | Antibacterial activity against hospital-acquired methicillin-resistant Staphylococcus aureus clinical isolate BJ068 from patient sputum by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. |
| AID533428 | Antimicrobial activity against Peptostreptococcus sp. assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID562941 | Effect on fbp69 gene expression in Clostridium difficile 6269 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID404948 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus isolate assessed as susceptible resistant isolates by CLSI dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea. |
| AID1879559 | Antibacterial activity against Fusobacterium nucleatum ATCC 10953 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID322785 | Antimicrobial activity against Bacteroides ovatus assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004. |
| AID534440 | Antimicrobial activity against Clostridium perfringens ATCC 13124 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID547520 | Antimicrobial activity against Streptococcus anginosus obtained from patient with cystic fibrosis assessed as non-susceptible isolates grown on mueller-Hinton blood agar at 2 ug/ml after 24 hrs at 37 degC by disk diffusion method in presence of 5% defribi | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. |
| AID528974 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus isolated from ICU patient respiratory tract assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID278667 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 2513 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm. |
| AID1879560 | Antibacterial activity against Fusobacterium nucleatum ATCC 25586 | 2022 | Journal of medicinal chemistry, 03-24, Volume: 65, Issue:6 | Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens. |
| AID531516 | Antibacterial activity against Bacteroides caccae assessed as percent resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Resistance trends of the Bacteroides fragilis group over a 10-year period, 1997 to 2006, in Madrid, Spain. |
| AID323004 | Antibacterial activity against drug-resistant Propionibacterium acnes P429:1 (SC) after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID534674 | Antimicrobial activity against Fusobacterium nucleatum ATCC 25586 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID1698702 | Antibacterial activity against Porphyromonas gingivalis JCM8525 by CLSI method | 2020 | Bioorganic & medicinal chemistry, 11-15, Volume: 28, Issue:22 | Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors. |
| AID278499 | Antibacterial activity against Pneumococcus DAW70 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID278485 | Antibacterial activity against Pneumococcus DAW19 isolated from sickle cell disease patient | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients. |
| AID285354 | Decrease in Panton-Valentine leukocidin level in community acquired methicillin-resistant Staphylococcus aureus HT20020488 in CYY medium | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. |
| AID548796 | Antimicrobial activity against Oxacillin-resistant coagulase-negative Staphylococcus assessed as percent resistant isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID574736 | Antimicrobial activity against Fusobacterium nucleatum after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID534468 | Antimicrobial activity against Bacteroides vulgatus GAI 0673 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID533659 | Antimicrobial activity against Staphylococcus aureus RN4220 | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus. |
| AID128555 | Bioactivity in blood, in Bacteroides fragilis infected mice following subcutaneous dose of 200 mg/kg after 45 mins of bleeding | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID1625275 | Antimalarial activity against Plasmodium falciparum W2 after 96 hrs | 2016 | Journal of medicinal chemistry, 06-23, Volume: 59, Issue:12 | Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action. |
| AID433189 | Antibacterial activity against Corynebacterium xerosis isolated from patient with diabetic foot infection assessed as percent resistant isolates after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | In vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. |
| AID508470 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2011 harboring mef(A) gene after 35 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID534667 | Antimicrobial activity against Prevotella intermedia ATCC 25611 by agar dilution method in presence of 5% laked sheep blood | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria. |
| AID508477 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 237 harboring mutation in L4 ribosomal protein after overnight incubation by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID573597 | Antibacterial activity against Fusobacterium necrophorum assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID562392 | Antimicrobial activity against Staphylococcus haemolyticus clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID562371 | Antimicrobial activity against erythromycin-nonsusceptible Streptococcus Group C clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID768027 | Antibacterial activity against Bacillus anthracis 34F2 Sterne by double-dilution technique | 2013 | Journal of medicinal chemistry, Jul-11, Volume: 56, Issue:13 | Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance. |
| AID533638 | Antimicrobial activity against Propionibacterium sp. assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID424422 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus HIP15178 isolated from patients surgical wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID508462 | Antibacterial activity against macrolide-resistant Streptococcus pneumoniae 2094 harboring erm(A) gene after 6 passages and 10 compound-free subculturing by retest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. |
| AID574724 | Antimicrobial activity against Prevotella buccae assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID535644 | Antimicrobial activity against Group B streptococcus serotype Ib N2 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID423272 | Antibacterial activity against 0.01 MOI wild type Chlamydia trachomatis L2/LGV/434/Bu infected in mouse L2 cells treated 2 hrs after infection measured on day 7 by plaque assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2. |
| AID574508 | Antimicrobial activity against Bacteroides distasonis assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID548257 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID562411 | Antimicrobial activity against erythromycin-susceptible Streptococcus Group G clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID129547 | In vivo antibacterial activity against Proteus vulgaris (UC no 347) infected mice after sc administration | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID574552 | Decrease in delta toxin levels in Staphylococcus aureus USA300 at subinhibitory concentrations after 24 hrs by RP-HPLC/ESI- MS | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus. |
| AID625291 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver function tests abnormal | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID425717 | Antimicrobial activity against Balamuthia mandrillaris ATCC 50209 infected in HBMEC assessed as inhibition of encystment at 10 ug/mL after 7 days | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytopathogenicity. |
| AID548473 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID41252 | In vitro activity against Bacteroides fragilis (SFM2929-1) | 1988 | Journal of medicinal chemistry, Aug, Volume: 31, Issue:8 | Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride. |
| AID535256 | Antimicrobial activity against vancomycin resistant Staphylococcus aureus VRS-4 expressing SCCmec type 4 element by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID534790 | Antimicrobial activity against community-acquired methicillin-resistant Staphylococcus aureus assessed as resistant isolates by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. |
| AID586053 | Antimicrobial activity against Staphylococcus aureus clone 4-4 harboring staphylococcal cassette chromosome mec element type 4 assessed as percent susceptible isolates by kirby-bauer method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Diversity of staphylococcal cassette chromosome mec elements in predominant methicillin-resistant Staphylococcus aureus clones in a small geographic area. |
| AID574528 | Antimicrobial activity against Prevotella intermedia assessed as percent resistant isolates after 48 hrs by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Antimicrobial susceptibility patterns for recent clinical isolates of anaerobic bacteria in South Korea. |
| AID573834 | Antibacterial activity against beta-lactamase producing Clostridium perfringens assessed as susceptible isolates by CLSI agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems. |
| AID41256 | In vitro antibacterial activity against the anaerobic Bacteroides fragilis (Strain UC no.6513) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2 | Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. |
| AID541030 | Induction of apoptosis in bovine BL3 cells assessed as late apoptotic cells after 24 hrs by annexin V/propidium iodide staining-based FACS analysis | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Theileria apicoplast as a target for chemotherapy. |
| AID584972 | Antibacterial activity against wild type Mycobacterium smegmatis after 24 generation times | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance. |
| AID528971 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolated from ICU patient urine assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006. |
| AID542388 | Antimicrobial activity against Staphylococcus aureus RN4220 transformed with Staphylococcus aureus ST398 plasmid pSCFS3 carrying cfr and fexA genes | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr. |
| AID562926 | Antimicrobial activity against Clostridium difficile CD196 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID322990 | Antibacterial activity against drug-resistant Propionibacterium acnes SW16 after 48 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Antipropionibacterial activity of BAL19403, a novel macrolide antibiotic. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1921 (32.76) | 18.7374 |
| 1990's | 944 (16.10) | 18.2507 |
| 2000's | 1208 (20.60) | 29.6817 |
| 2010's | 1324 (22.58) | 24.3611 |
| 2020's | 467 (7.96) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.
| This Compound (103.18) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 892 (14.17%) | 5.53% |
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 513 (8.15%) | 6.00% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 1,141 (18.12%) | 4.05% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 21 (0.33%) | 0.25% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 3,730 (59.23%) | 84.16% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis [NCT04039750] | Phase 2 | 200 participants (Anticipated) | Interventional | 2019-07-25 | Recruiting | ||
| [NCT00694928] | Phase 3 | 843 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| Efficacy & Safety of Clindamycin Phosphase 1.2% and Tretinoin 0.025% Gel vs. Vehicle for the Treatment of Acne and Acne-Induced Post Inflammatory Hyperpigmentation in Patients With Skin of Color [NCT01111994] | Phase 4 | 30 participants (Anticipated) | Interventional | 2009-11-30 | Active, not recruiting | ||
| Phase III Comparative Study of Efficacy of 10 mg Dequalinium Chloride (Fluomizin) in the Local Treatment of Bacterial Vaginosis [NCT01125410] | Phase 3 | 321 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
| Investigating Anti-inflammatory Effects of Topical Antibiotics in an LPS Skin Challenge Model [NCT03779360] | 32 participants (Actual) | Interventional | 2018-10-12 | Completed | |||
| The Role of Antibiotics in the Reduction of Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax: A Prospective, Double-Blinded Study [NCT01127880] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2005-07-31 | Completed | ||
| A Randomized, Double-Blind, Multiple-Site, Placebo-Controlled Study Comparing Two 1% Clindamycin/5% Benzoyl Peroxide Topical Gel Formulations in the Treatment of Moderate to Severe Acne Vulgaris [NCT01044264] | 602 participants (Actual) | Interventional | 2007-12-31 | Completed | |||
| A Phase IV, Open-Label Study Evaluating the Use of Solodyn (Minocycline HCL Extended-Release Tablets), Ziana, and Triaz Foaming Cloths as Combination Acne Therapy Prior to Treatment With Isotretinoin [NCT01206348] | Phase 4 | 97 participants (Actual) | Interventional | 2010-09-30 | Completed | ||
| Randomized Control Trial Comparing Efficacy of Antibiotic Therapy Alone Versus Antibiotic Therapy in Conjunction With Quadruple Pulse Therapy Using NdYag Laser in Treatment of Hidradenitis Suppurativa [NCT01063270] | 18 participants (Actual) | Interventional | 2010-02-28 | Completed | |||
| A Phase 1, Single Center, Randomized, Open-Label Study to Evaluate the Bioavailability of Clindamycin From Clindamycin 1%-Benzoyl Peroxide 3% Gel, Topical Gel (Clindamycin 1%- Benzoyl Peroxide 5%), and Once Daily Gel (Clindamycin 1%-Benzoyl Peroxide 5%) i [NCT01132443] | Phase 1 | 72 participants (Actual) | Interventional | 2010-05-06 | Completed | ||
| Preemptive Therapy Study of Cetuximab(Erbitux®)Induced Skin Rash Using Doxycycline, Sunscreen, Hydrocortisone and Moisturizer in Colorectal and Head and Neck Cancer Patients [NCT01874860] | Phase 2 | 24 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| A Randomized, Placebo-controlled, Evaluator-blinded, Study to Assess the Anti-inflammatory Effects of Topical Erythromycin and Clindamycin in Patients With Inflammatory Facial Acne [NCT03883269] | Phase 4 | 30 participants (Anticipated) | Interventional | 2018-03-20 | Recruiting | ||
| Antimicrobial Efficacy of Synthetic Versus Herbal Intracanal Medicaments Against Enterococcus Faecalis [NCT06006663] | Phase 2/Phase 3 | 32 participants (Anticipated) | Interventional | 2023-08-26 | Not yet recruiting | ||
| Randomized Noninferiority Study of an Antibacterial Envelope Alone Versus Envelope Plus Intraoperative Antibacterial Irrigant and Postoperative Antibiotics to Prevent Cardiac Implantable Electronic Device Infections in High-Risk Patients [NCT02809131] | Phase 3 | 1,010 participants (Actual) | Interventional | 2016-04-01 | Completed | ||
| The Efficacy of Laser Hair Removal Therapy in Patients With Mild to Moderate HS, a Randomized Controlled Trial. [NCT05762484] | 58 participants (Anticipated) | Interventional | 2023-04-30 | Not yet recruiting | |||
| A Multi-center, Randomized, Single-blind, Paralelle, Positive Controlled Phase III Study to Evaluate the Efficacy and Safety of Adapalene-Clindamycin Combination Gel in the Treatment of Moderate Acne Vulgaris [NCT03615768] | Phase 3 | 1,617 participants (Actual) | Interventional | 2018-08-14 | Completed | ||
| Multicentre Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria in African Children [NCT01361269] | Phase 2 | 100 participants (Anticipated) | Interventional | 2011-06-30 | Not yet recruiting | ||
| Prospective Randomized Study to Compare Clinical Outcomes in Patients With Osteomyelitis Treated With Intravenous Antibiotics Versus Intravenous Antibiotics With an Early Switch to Oral Antibiotics [NCT02099240] | Early Phase 1 | 11 participants (Actual) | Interventional | 2014-03-06 | Terminated(stopped due to Not enough patient enrollment and lack of staffing) | ||
| A Randomized Clinical Trial to Measure the Impact of Retreatment With an Artemisinin-based Combination on Malaria Incidence and Its Potential Selection of Resistant Strains [NCT01374581] | Phase 3 | 2,117 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
| A Double-blind, Placebo-controlled Multicenter Trial on the Effect of Clindamycin and a Live Biotherapeutic on the Reproductive Outcomes of IVF Patients With Abnormal Vaginal Microbiota [NCT05166746] | Phase 2 | 333 participants (Anticipated) | Interventional | 2017-12-07 | Recruiting | ||
| Effect of Gentamicin Versus Clindamycin Versus Normal Saline Lavage of the Axillary Surgical Bed After Lymph Node Dissection on Drainage Discharge Volume [NCT02314806] | Phase 3 | 51 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Testing the Ability of a Microbiome - Focused Intervention to Reduce HIV Susceptibility in Ugandan Men [NCT03412071] | 125 participants (Anticipated) | Interventional | 2017-12-07 | Recruiting | |||
| Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants [NCT03511118] | 1,600 participants (Anticipated) | Observational | 2018-10-04 | Recruiting | |||
| Randomized Controlled Research of the Application of Triple Antibiotic Paste in Primary Teeth With [NCT02196740] | 100 participants (Anticipated) | Interventional | 2013-06-30 | Active, not recruiting | |||
| A Randomized Controlled Trial Assessing Noninferiority of Three Antimicrobial Regimens for the Treatment of Grade III Open Fractures [NCT03560232] | Phase 4 | 17 participants (Actual) | Interventional | 2018-07-09 | Terminated(stopped due to Unable to recruit patients in a timely fashion and unable to recruit sufficient patients) | ||
| Oral Versus Intravenous Antibiotics for the Management of the Osteomyelitis of the Jaws: An Open-Label Non-Inferiority Single-Arm Clinical Trial [NCT05867654] | 100 participants (Anticipated) | Observational | 2023-11-01 | Not yet recruiting | |||
| Pilot for Vancomycin and Tobramycin Powder Use in Acute Open Fractures in the Emergency Department [NCT05849090] | Early Phase 1 | 50 participants (Anticipated) | Interventional | 2023-03-27 | Enrolling by invitation | ||
| Randomized, 2-Way Crossover, Bioequivalence Study of Clindamycin 300 mg Capsules and Cleocin Hcl Administered as 1 x 300 mg Capsule in Healthy Subjects Under Fed Conditions [NCT00836004] | Phase 1 | 24 participants (Actual) | Interventional | 2003-11-30 | Completed | ||
| A Randomized Clinical Trial Between Clindamycin Once and Thrice a Day in Septic Abortion. [NCT02309346] | Phase 4 | 190 participants (Anticipated) | Interventional | 2014-12-31 | Recruiting | ||
| Randomized, 2-Way Crossover, Bioequivalence Study of Clindamycin 300 mg Capsules and Cleocin HCl Administered as 1 x 300 mg Capsule in Healthy Subjects Under Fasting Conditions [NCT00836056] | Phase 1 | 24 participants (Actual) | Interventional | 2003-11-30 | Completed | ||
| [NCT00616330] | Phase 3 | 1,443 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| A Phase 3b, Comparative and Randomized Study to Assess the Efficacy and Safety of an Intravaginal Ovule Combination of Ketoconazole and Clindamycin Compared With an Intravaginal Cream Combination of Tetracycline and Amphotericin B for the Treatment of Bac [NCT01293643] | Phase 3 | 99 participants (Actual) | Interventional | 2010-05-31 | Completed | ||
| A Phase 4, Single-Blind, Randomized, Study to Compare the Tolerability and Efficacy of Tazorac Cream When Used in Combination With Either Duac Gel or Acanya Gel for the Treatment of Facial Acne Vulgaris [NCT01016977] | Phase 4 | 40 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
| A Phase 3 Multi-Center, Double-Blind, Placebo-Controlled, Randomized Study of DARE-BV1 in the Treatment of Bacterial Vaginosis [NCT04370548] | Phase 3 | 307 participants (Actual) | Interventional | 2020-06-16 | Completed | ||
| Evaluation of Posterior Segment Intrusion Using Miniplates in Skeletal ClassII Hyperdivergent Adolescence: A Randomized Control Trial [NCT02674191] | 24 participants (Actual) | Interventional | 2016-05-31 | Active, not recruiting | |||
| A Randomized Double Blind Multiple Center Placebo Controlled Study Comparing CLBG and Benzoyl Peroxide Gel 1%/5% to BenzaClin® (Clindamycin 1%/Benzoyl Peroxide 5%) Topical Gel in the Treatment of Acne Vulgaris [NCT02595034] | Phase 1 | 1,000 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| A Clinical Assessment of Combination Therapy With Differin® Gel, 0.3% With Duac® (Clindamycin/Benzoyl Peroxide Gel) in Subjects With Acne Vulgaris [NCT00671749] | Phase 4 | 100 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| A Randomized, Double-Blind, Multiple Center Placebo Controlled Study Comparing Taro Product to RLD and Both Treatments to a Placebo Control in the Treatment of Acne Vulgaris. [NCT04134273] | Phase 1 | 1,260 participants (Actual) | Interventional | 2019-03-20 | Completed | ||
| Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne [NCT00837213] | Phase 4 | 33 participants (Actual) | Interventional | 2007-08-31 | Completed | ||
| A Single-blind, Randomized, Comparative Pilot Study Evaluating the Tolerability of Two Topical Combination Therapies in the Treatment of Acne Vulgaris [NCT00887484] | Phase 4 | 50 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| A Single-blind, Randomized, Comparative Split-face Study Evaluating the Tolerability of Clindamycin and Benzoyl Peroxide Gel to Benzoyl Peroxide/Adapalene Gel in the Treatment of Acne Vulgaris. [NCT00964223] | Phase 4 | 28 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting [NCT04516148] | Phase 4 | 32 participants (Actual) | Interventional | 2018-05-29 | Completed | ||
| Target Attainment and Pharmacokinetics of Antimicrobials in Non-critically Ill Surgery Patients [NCT03120663] | 120 participants (Anticipated) | Observational | 2016-11-30 | Recruiting | |||
| Peritonsillar Abscess: Aspiration Versus Tonsillectomy a Chaud [NCT03326661] | 128 participants (Anticipated) | Interventional | 2017-11-10 | Not yet recruiting | |||
| Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Postoperative Pain and Analytic Acute Phase Reactants Following Laparoscopic Sleeve Gastrectomy [NCT02479971] | Phase 3 | 60 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Comparative Effectiveness of Adjunctive Clindamycin Versus Linezolid for β-lactam Treated Patients With Invasive Group A Streptococcal Infections: A Target Trial Emulation [NCT06126263] | 1,000 participants (Anticipated) | Observational | 2023-01-01 | Active, not recruiting | |||
| Clindamycin Versus Amoxicillin With Clavulanic Acid in Prevention of Early Dental Implants Failure [NCT04980170] | Early Phase 1 | 100 participants (Anticipated) | Interventional | 2021-11-01 | Not yet recruiting | ||
| Multicenter, Double-blind, Randomized, Parallel-group, Placebo-controlled Study to Evaluate the Bioequivalence of a Generic Clindamycin 1.2% and Benzoyl Peroxide 3.75% Gel to Onexton® Gel in Subjects With Acne Vulgaris [NCT02616614] | Phase 3 | 862 participants (Actual) | Interventional | 2015-05-31 | Completed | ||
| Rifampicin Combination Therapy Versus Targeted Antimicrobial Monotherapy in the Oral Antimicrobial Treatment Phase of Staphylococcal Prosthetic Joint Infection [NCT06172010] | Phase 4 | 316 participants (Anticipated) | Interventional | 2023-04-01 | Recruiting | ||
| Reducing INfection at the Surgical SitE With Antibiotic Irrigation During Ventral Hernia Repair (RINSE Trial) [NCT03945357] | Phase 3 | 250 participants (Actual) | Interventional | 2019-05-15 | Completed | ||
| Treatment of BV With First Deqularum and Then Direkt After With Vaginal Clindamycin Cream. [NCT04067531] | Phase 3 | 50 participants (Anticipated) | Interventional | 2020-08-01 | Recruiting | ||
| The Potential Impact of Clindamycin on Neurosurgery Patients. [NCT06068673] | 44 participants (Anticipated) | Interventional | 2023-03-01 | Recruiting | |||
| A Phase 3 Multicenter, Randomized, Double-Blind, Active And Vehicle-Controlled Study Of The Safety And Efficacy Of CT Gel in Subjects With Acne Vulgaris [NCT00689117] | Phase 3 | 1,649 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| A Single Center Prospective Randomized Control Trial Investigating the Short-term and Long-term Effects of Intraoperative Prophylactic Antibiotics/Antiseptics on Surgical Outcomes in Chinese Post-mastectomy Breast Reconstruction Patients [NCT03742908] | 291 participants (Anticipated) | Interventional | 2018-06-16 | Recruiting | |||
| A Randomized, Placebo Controlled Trial of the Effect of Prophylactic Antibiotics on Surgical Site Infection Lower Limb Skin Excisions [NCT03357419] | 0 participants (Actual) | Interventional | 2021-03-31 | Withdrawn(stopped due to difficulties in production placebo antibiotics) | |||
| A Phase 3 Multicenter, Randomized, Double-Blind, Active And Vehicle-Controlled Study Of The Safety And Efficacy Of A Clindamycin / Benzoyl Peroxide Gel Versus Clindamycin Gel Versus Benzoyl Peroxide Gel Versus Vehicle Gel In Subjects With Acne Vulgaris [NCT00776919] | Phase 3 | 1,315 participants (Actual) | Interventional | 2008-10-31 | Completed | ||
| Randomized Multicenter Trial for the Prevention of Preterm Delivery by Testing for and Treatment of Bacterial Vaginosis in the First Trimester of Pregnancy [NCT00642980] | Phase 4 | 3,105 participants (Actual) | Interventional | 2006-04-30 | Completed | ||
| [NCT00664248] | Phase 3 | 1,414 participants (Actual) | Interventional | 2006-10-31 | Completed | ||
| Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs [NCT04278404] | 5,000 participants (Anticipated) | Observational | 2020-03-05 | Recruiting | |||
| The PROTECT Study: A Phase II, Open-Label Trial of PROphylactic Skin Toxicity ThErapy With Clindamycin and Triamcinolone in Glioblastoma Patients Treated With Tumor Treating Fields [NCT04469075] | Phase 2 | 58 participants (Anticipated) | Interventional | 2020-07-09 | Recruiting | ||
| A Double-Blind, Placebo-Controlled, Pilot Study to Determine the Safety and Efficacy of Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel For The Treatment of Rosacea Over 12 Weeks [NCT00823901] | Phase 2/Phase 3 | 83 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| A Phase 3, Multicenter, Randomized, Double-Blind Study To Evaluate The Safety And Efficacy Of Tigecycline Versus Comparator (Clindamycin Or Vancomycin) For The Treatment Of Complicated Skin And Skin Structure Infections, Including Those Due To MRSA, In Pe [NCT00911573] | Phase 3 | 0 participants (Actual) | Interventional | 2011-08-31 | Withdrawn | ||
| A Placebo Control, Multicenter, Randomized, Double Blind, Multi-formula Groups, and Parallel Phase Ⅰb+Ⅱa Study Evaluating the Safety and Efficacy of Compound Adapalene and Clindamycin Hydrochloride Gel in Treatment of Patients With Acne [NCT02593383] | Phase 1/Phase 2 | 245 participants (Actual) | Interventional | 2015-03-01 | Completed | ||
| Randomized, Double-Blind Trial of Clindamycin, Trimethoprim-Sulfamethoxazole, or Placebo for Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureus [NCT00730028] | Phase 2 | 1,310 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| Treatment of Chorioamnionitis After Delivery [NCT00814905] | 300 participants (Anticipated) | Interventional | 2009-06-30 | Recruiting | |||
| Pharmacological Interaction of Rifampicin on Clindamycin in Staphylococcic Osteoarticular Infections [NCT02782078] | 20 participants (Actual) | Interventional | 2017-03-06 | Completed | |||
| Effect of Irrigation With Antibiotic-containing Solutions Versus Sodium Hypochlorite on Postoperative Pain and Intra-canal Bacteria in Teeth With Necrotic Pulps (a Randomized Double-blind Clinical Trial) [NCT04035070] | Phase 4 | 51 participants (Anticipated) | Interventional | 2021-01-31 | Not yet recruiting | ||
| Two-week Study to Determine and Compare the Tolerance and Irritation Potential of Topical Antibiotic and Benzoyl Peroxide to Benzoyl Peroxide and Adapalene Topical Gel Acne Medications [NCT00926367] | Phase 4 | 52 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| Two-week Study to Determine and Compare the Tolerance and Irritation Potential of Duac® Topical Gel (Clindamycin 1% and Benzoyl Peroxide 5%) to ACANYA™ Gel (Clindamycin Phosphate 1.2% and Benzoyl Peroxide 2.5%) Topical Acne Medications [NCT01015638] | Phase 4 | 36 participants (Actual) | Interventional | 2009-08-31 | Completed | ||
| [NCT00663286] | Phase 3 | 1,399 participants (Actual) | Interventional | 2006-10-31 | Completed | ||
| Comparative Efficacy of Different Oral Doses of Clindamycin in Preventing Post-operative Sequelae of Lower Third Molar Surgery - a Randomized, Triple-blind Study [NCT05268835] | Phase 4 | 300 participants (Anticipated) | Interventional | 2020-02-01 | Recruiting | ||
| A Multicenter, Randomized, Observer-Blinded, Active-Controlled Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of Ceftaroline Versus Comparator in Pediatric Subjects With Acute Bacterial Skin and Skin Structure Infections [NCT01400867] | Phase 2/Phase 3 | 163 participants (Actual) | Interventional | 2011-12-31 | Completed | ||
| A Multi-center, Randomized, Double-blind, Vehicle-Controlled, Phase 2 Study of the Safety and Efficacy of Benzoyl Peroxide/Clindamycin Gel and Tazarotene Cream When Used in Combination in the Treatment of Acne Vulgaris [NCT00713609] | Phase 2 | 591 participants (Actual) | Interventional | 2008-06-30 | Completed | ||
| Aspiration or Surgical Drainage of Perianal Abscess. A Randomized Controlled Clinical Study [NCT02585141] | 111 participants (Actual) | Interventional | 2015-10-31 | Completed | |||
| A Multi Center Double Blind Randomized Placebo Controlled Parallel Group Study Comparing Clindamycin and Benzoyl Peroxide Gel 1.2%/3.75% to Onexton™ Gel and Both Active Treatments to a Placebo Control in the Treatment of Acne Vulgaris [NCT02578043] | Phase 1 | 844 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| "Strategies Using Off-Patent Antibiotics for Methicillin-Resistant Staphylococcus Aureus (STOP MRSA) - A Phase IIB, Multi-Center, Randomized, Double-Blind Clinical Trial" [NCT00729937] | Phase 2/Phase 3 | 2,265 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| Laser Therapy for Perioral Dermatitis [NCT03779295] | 0 participants (Actual) | Interventional | 2018-11-01 | Withdrawn(stopped due to No subjects enrolled.) | |||
| A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Trimethoprim / Sulfamethoxazole in the Treatment of Mild-to-Moderate PCP in Patients With AIDS [NCT00000640] | Phase 3 | 290 participants | Interventional | Completed | |||
| The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDS [NCT00000717] | 50 participants | Interventional | Completed | ||||
| Phase III, Open Label, Randomized, Multicenter Study to Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin 100mg and Ketoconazole 400mg in Vaginal Capsules, Compared to Combination of Tetracycline 100mg and Amphotericin B 50mg in Vagin [NCT00889356] | Phase 3 | 160 participants (Anticipated) | Interventional | 2009-09-30 | Not yet recruiting | ||
| Comparison of Outcomes in Rhinoplasty With the Use of Intraoperative Versus Postoperative Antibiotics [NCT04194216] | Phase 3 | 864 participants (Anticipated) | Interventional | 2020-05-20 | Enrolling by invitation | ||
| The Pulsed Dye Laser as an Adjuvant Treatment Modality in Acne Vulgaris - a Randomized Controlled Single Blinded Trial [NCT01052246] | 80 participants (Actual) | Interventional | 2008-10-31 | Completed | |||
| A Randomized Controlled Trial of Systemic and Topical Treatments for Rash Secondary to Erlotinib in Advanced Stage IIIB or IV Non-Small Cell Lung Cancer [NCT00473083] | Phase 2 | 150 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| A Single-Center, Evaluator-Blinded, Randomized, Placebo-Controlled, Phase 1 Clinical Trial Evaluating the Photoallergic Potential of Topically Applied Clindamycin Phosphate 1.0% and Tretinoin 0.025% (CT Gel) in Healthy Volunteers [NCT01915758] | Phase 1 | 64 participants (Actual) | Interventional | 2008-11-21 | Completed | ||
| Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth [NCT01945450] | 300 participants (Anticipated) | Interventional | 2014-01-31 | Not yet recruiting | |||
| A Comparative Assessment of the Efficacy of Fosmidomycin-Clindamycin Versus Sulfadoxine-Pyrimethamine for the Treatment of Children With Uncomplicated Plasmodium Falciparum Malaria [NCT00214643] | Phase 3 | 160 participants | Interventional | 2005-06-30 | Completed | ||
| [NCT00398658] | Phase 4 | 0 participants | Interventional | 2002-03-31 | Completed | ||
| A Randomised Control Trial to Determine Whether a 5 Day Course of Antibiotics is More Clinically and Cost Effective Than a 24 Hour Prophylactic Course for the Prevention of Surgical Site Infection Following Lower Limb Amputation [NCT02018094] | Phase 4 | 160 participants (Actual) | Interventional | 2013-10-08 | Completed | ||
| A Randomized, Double-Blind, Multiple Center Placebo Controlled Study Comparing Taro Product to RLD and Both Treatments to a Placebo Control in the Treatment of Acne Vulgaris [NCT04321070] | Phase 1 | 550 participants (Actual) | Interventional | 2019-09-09 | Completed | ||
| CAT BITE Antibiotic Prophylaxis and Durations for the Hand/Forearm (CATBITE): A Prospective, Randomized, Placebo-controlled, Double-blinded, Clinical Trial [NCT05846399] | Phase 4 | 72 participants (Anticipated) | Interventional | 2023-09-07 | Recruiting | ||
| Role in Emergent Cerclage of Indomethacin and Antibiotics [NCT01114516] | 53 participants (Actual) | Interventional | 2010-03-31 | Completed | |||
| Drug Use Evaluation Study of Clindamycin in Critical Care Units in Alexandria Main University Hospital [NCT05223400] | 99 participants (Actual) | Observational | 2022-03-01 | Completed | |||
| Comparison of Safety and Efficacy of Tazarotene 0.1% Plus Clindamycin 1% Gel vs. Adapalene 0.1% Plus Clindamycin 1% Gel in the Treatment of Facial Acne Vulgaris: A Randomized Controlled Trial [NCT02721173] | Phase 4 | 60 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| Oral Corticosteroids Therapy and Interstitial Fibrosis in Patients With Pneumocystis Jirovecii Pneumonia (PCP) and pO2 of >70 at Presentation. [NCT00636935] | Phase 4 | 0 participants (Actual) | Interventional | 2008-02-29 | Withdrawn(stopped due to No patient completed protocol) | ||
| Does Prophylactic Antibiotic Decrease the Rate of Urinary Tract Infection After Robot Assisted Radical Cystectomy [NCT04502095] | Phase 4 | 100 participants (Anticipated) | Interventional | 2020-09-02 | Recruiting | ||
| Adjunctive Clindamycin Versus Standard of Care for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled, Open-label Superiority Phase 4 Trial [NCT05899140] | Phase 4 | 100 participants (Anticipated) | Interventional | 2024-02-01 | Not yet recruiting | ||
| Pilot Study of Tolerability and Effectivity Following Application of Two Combination Topical Acne Products Clindamycin 1% and 0.025% Tretinoin Gel (Acnatac® Gel), Adapalen 0,1% and Benzoyl Peroxide 2,5% Gel (Epiduo® Gel) [NCT02731105] | Phase 4 | 22 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
| Two-week Study to Determine and Compare the Tolerance and Irritation Potential of Clindamycin and Benzoyl Peroxide to Dapsone Gel Topical Acne Medications [NCT00964366] | Phase 4 | 53 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| [NCT00372294] | Phase 3 | 0 participants | Interventional | 2005-07-31 | Active, not recruiting | ||
| A Pilot Study to Evaluate the Efficacy of Fixed Dose Combination Clindamycin Phosphate 1.2%/Tretinoin 0.025% Gel Alone Versus Fixed Dose Combination Clindamycin Phosphate 1.2%/Tretinoin 0.025% Gel Plus Benzoyl Peroxide 6% Foaming Cloths in the Treatment o [NCT01422785] | Phase 4 | 40 participants (Anticipated) | Interventional | 2011-07-31 | Recruiting | ||
| Oral vs Intravenous Antibiotics for Treatment of Periprosthetic Joint Infection [NCT04723940] | Phase 3 | 308 participants (Anticipated) | Interventional | 2021-01-25 | Enrolling by invitation | ||
| Phase IV Clinical Study Of Clindamycin Phosphate Topical Gel In The Treatment Of Acne Vulgaris [NCT00219570] | Phase 4 | 134 participants (Actual) | Interventional | 2005-01-31 | Completed | ||
| Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy [NCT02579161] | Phase 3 | 98 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| Impact of Prophylactic Perioperative Antibiotic Administration on Surgical Site Infections Following Implant-based Breast Reconstruction. [NCT01899690] | Phase 4 | 0 participants (Actual) | Interventional | 2016-06-30 | Withdrawn(stopped due to The study was withdrawn prior to IRB approval.) | ||
| Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS) [NCT03261830] | Phase 4 | 168 participants (Actual) | Interventional | 2017-08-18 | Completed | ||
| Cutibacterium Acnes Persists Despite Topical Clindamycin and Benzoyl Peroxide [NCT03257202] | Phase 2 | 12 participants (Actual) | Interventional | 2017-09-11 | Completed | ||
| Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse [NCT00002064] | 0 participants | Interventional | Completed | ||||
| Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction [NCT01244698] | Phase 4 | 132 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
| Management of Vaginal Complaints: A Pilot Study Within a Practice-Based Research Network [NCT00503542] | Early Phase 1 | 46 participants (Actual) | Interventional | 2007-02-28 | Completed | ||
| Antibiotics for Severe Perineal Laceration to Prevent Infection Following Repair [NCT04573504] | Phase 4 | 274 participants (Anticipated) | Interventional | 2020-09-23 | Recruiting | ||
| Prospective Randomized Evaluation of Antibiotic Regimen Following Appendectomy for Perforated Appendicitis [NCT00195923] | 100 participants | Observational | 2005-04-30 | Completed | |||
| Evaluation of Fosmidomycin in Combination With Clindamycin in Children With Acute Uncomplicated Plasmodium Falciparum Malaria [NCT00217451] | Phase 2 | 51 participants | Interventional | 2002-06-30 | Completed | ||
| Comparison of the Efficacy of Clindamycin Phosphate 1% Gel Versus Once-daily Dapsone 5% Gel in the Treatment of Moderate Acne Vulgaris [NCT05926869] | Phase 2 | 100 participants (Actual) | Interventional | 2022-08-01 | Completed | ||
| A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS [NCT00000674] | 30 participants | Interventional | Completed | ||||
| A Randomized, Double-blind, Multicentric, Parallel-group, Active and Placebo Controlled, Three Arm Clinical Study to Compare the Efficacy and Safety of Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel (of Cadila Healthcare Limited, India) Versus DUAC® [NCT02005666] | Phase 3 | 850 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Pharmacokinetics of Clindamycin and Trimethoprim-sulfamethoxazole in Infants and Children Using PBPK [NCT02475876] | Phase 1 | 51 participants (Actual) | Interventional | 2015-11-30 | Completed | ||
| Clinical Implication of Next Generation Sequencing of Urinary Bacteria in Patients With Low Colony Forming Units of Bacteria in Traditional Urine Culture [NCT05206500] | Phase 4 | 100 participants (Anticipated) | Interventional | 2022-05-17 | Recruiting | ||
| The Efficacy and Safety Study of Clindamycin Palmitate Hydrochloride Dispersible Tablet for the Treatment of Bacterial Vaginosis [NCT03080740] | Phase 4 | 300 participants (Anticipated) | Interventional | 2016-07-31 | Recruiting | ||
| A Phase 2, Open-Label, Randomized Trial Evaluating the Impact of Enhanced Versus Standard Dermatologic Management on Selected Dermatologic Adverse Events Among Patients With Locally Advanced or Metastatic EGFR-Mutated NSCLC Treated First-Line With Amivant [NCT06120140] | Phase 2 | 180 participants (Anticipated) | Interventional | 2024-03-08 | Not yet recruiting | ||
| Treatment of Methicillin-sensitive Staphylococcus Aureus Orthopaedic Infections With Clindamycin in Combination With Rifampin or Levofloxacin: a Randomized Pharmacological and Clinical Study (the CLINDOS Trial) [NCT01500837] | 23 participants (Actual) | Interventional | 2010-10-31 | Completed | |||
| A Comparative Open Labeled Clinical Study to Evaluate the Efficacy and Tolerability of Two Different Intravaginal Formulations Containing a Combination of Clindamycin and Clotrimazole in Vaginal Infections [NCT01697826] | Phase 4 | 73 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
| Comparing Post-drainage Treatment of Peritonsillar Abscesses With Antibiotics (Clavulin or Clindamycin) to Treating With Placebo - a Double-blinded Randomized Control Trial [NCT01715610] | 0 participants (Actual) | Interventional | 2012-05-24 | Withdrawn(stopped due to unsuccessful recruitment) | |||
| Prospective,Randomized,Open Label,European Multicenter Study of the Efficacy of the Linezolid-rifampin Combination Versus Standard of Care in the Treatment of Gram-positive. [NCT01757236] | Phase 2 | 100 participants (Anticipated) | Interventional | 2012-10-31 | Recruiting | ||
| A Multicenter, Double-Blind, Randomized, Vehicle-Controlled, Parallel-Group Study Comparing Taro Pharmaceutical Inc.'s Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2%/2.5% to the Reference Listed Acanya® (Clindamycin Phosphate and Benzoyl Peroxide)Ge [NCT01769235] | Phase 1 | 1,215 participants (Actual) | Interventional | 2012-11-30 | Completed | ||
| A Randomized, Double-Blind, Multiple-Site, Placebo-Controlled, Parallel Design Study Comparing Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Taro Pharmaceuticals Inc.) to Duac® Topical Gel Clindamycin 1%/Benzoyl Peroxide 5% (Stiefel) in the Treatment of [NCT01769664] | Phase 1 | 650 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| A Multicenter, Double-blind, Randomized, Vehicle-controlled, Parallel-group Study Comparing Clindamycin Phosphate and Benzoyl Peroxide Gel and Acanya® 1.2%/2.5% and Both Active Treatments to Vehicle Control for Treating Acne Vulgaris [NCT01788384] | Phase 3 | 708 participants (Actual) | Interventional | 2012-07-31 | Completed | ||
| Early Oral Switch Therapy in Low-risk Staphylococcus Aureus Bloodstream Infection [NCT01792804] | Phase 3 | 215 participants (Actual) | Interventional | 2013-12-31 | Completed | ||
| Clindamycin to Reduce Preterm Birth in a Low Resource Setting: A Randomized Placebo-controlled Trial [NCT01800825] | Phase 4 | 1,726 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
| Orthognathic Surgery and Postoperative Antibiotic Use [NCT01823523] | 300 participants (Anticipated) | Interventional | 2013-06-30 | Recruiting | |||
| A Multi-Center, Double-Blind, Randomized, Vehicle-Controlled, Parallel-Group Study to Compare Perrigo Israel Pharmaceuticals, Ltd., Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel to a Comparator Clindamycin / Benzoyl Peroxide Topical Gel, and Both Active [NCT01138514] | Phase 3 | 1,555 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
| [NCT02515305] | Phase 3 | 890 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| [NCT01231334] | Phase 4 | 286 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| Multicenter Pilot Study to Compare the Efficacy of a Combination of Vaginal Capsules With Acid Boric, L.Gasseri and L.Rhamnosus Versus the Reference Medication in Patients With Vaginal Candidiasis or Bacterial Vaginosis [NCT02860845] | Phase 4 | 48 participants (Actual) | Interventional | 2016-07-12 | Completed | ||
| Antibiotic Safety in Infants With Complicated Intra-Abdominal Infections (SCAMP Trial) [NCT01994993] | Phase 2/Phase 3 | 260 participants (Actual) | Interventional | 2013-12-31 | Completed | ||
| Safety and Pharmacokinetics of Multiple-Dose Intravenous and Oral Clindamycin in Pediatric Subjects With BMI ≥ 85th Percentile (NICHD): CLIN01 [NCT01744730] | Phase 1 | 22 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| A Multi-Center, Double-Blind, Randomized, Vehicle-Controlled, Parallel-Group Study Comparing Clindamycin 1% Gel To Clindamycin 1% Gel (Greenstone LLC) and Both Active Treatments to Vehicle Control in the Treatment of Acne Vulgaris [NCT03522441] | Phase 3 | 1,125 participants (Actual) | Interventional | 2018-04-27 | Completed | ||
| Interventional Bioremediation of Microbiota in Metabolic Syndrome [NCT02730962] | Phase 2 | 12 participants (Actual) | Interventional | 2016-06-30 | Terminated(stopped due to Delays in IND approval caused a lack of funding to conduct the trial.) | ||
| A Pilot Study to Evaluate the Safety and Tolerability of CeraVe® Lotion Followed by Fixed Dose Clindamycin Phosphate 1.2% / Benzoyl Peroxide 2.5% Gel in the Morning in Combination With CeraVe® Lotion Followed by Tretinoin 0.05% Gel in the Evening for the [NCT01448733] | Phase 4 | 20 participants (Actual) | Interventional | 2011-07-31 | Active, not recruiting | ||
| The Penile Microbiome in Partners of Women With Recurrent BV and Its Response to Decolonization Protocol [NCT05963711] | 100 participants (Anticipated) | Interventional | 2022-10-17 | Recruiting | |||
| DAICY Trial - Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture: A Register-based Cluster-randomized Cross-over Controlled Trial [NCT05164081] | Phase 3 | 7,000 participants (Anticipated) | Interventional | 2022-01-01 | Recruiting | ||
| Pharmacokinetics of Antistaphylococcal Antibiotics in Infants [NCT01728363] | Phase 1 | 63 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria in Children [NCT01464138] | Phase 2 | 52 participants (Actual) | Interventional | 2010-09-30 | Completed | ||
| A Single-Center, Evaluator-Blinded, Randomized, Placebo Controlled, Phase 1 Clinical Trial Evaluating The Phototoxic Potential Of Topically Applied Clindamycin 1.0% - Tretinoin 0.025% Gel (Ct Gel) In Healthy Volunteers [NCT01929278] | Phase 1 | 37 participants (Actual) | Interventional | 2008-12-08 | Completed | ||
| Efficacy of Amoxicillin-metronidazole Compared to Clindamycin in the Treatment of Periodontitis in Patients With Diabetes [NCT03374176] | Phase 3 | 42 participants (Actual) | Interventional | 2014-03-31 | Completed | ||
| A Double Blind Randomised Control Trial to Measure the Effect of the Addition of Clindamycin to Flucloxacillin for the Treatment of Limb Cellulitis [NCT01876628] | Phase 4 | 410 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| A Randomized Placebo-controlled Double-blinded Trial of the Treatment of MRSA Throat Carriage With Either Standard Decolonization Therapy or Standard Decolonization Therapy Combined With Oral Clindamycin [NCT04104178] | Phase 3 | 80 participants (Anticipated) | Interventional | 2020-05-20 | Recruiting | ||
| Adherence to ZIANA (Clindamycin Phosphate 1.2% With Tretinoin 0.025%)Gel Compared to Generic Topical Clindamycin Plus Generic Topical Tretinoin in Subjects With Mild to Moderate Acne Vulgaris [NCT01047189] | Phase 4 | 26 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| Prevention of Arrhythmia Device Infection Trial (PADIT) Cluster Crossover Pilot Study [NCT01613092] | Phase 4 | 241 participants (Actual) | Interventional | 2011-05-31 | Completed | ||
| Comparison Between Oral Clindamycin Vs Metronidazole for the Treatment of Abnormal Vaginal Flora in High Risk Pregnancies [NCT01722708] | 169 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| Antibiotic Prophylaxis for Prevention of Infection in Emergency Department Patients With Simple Hand Lacerations [NCT01155154] | 73 participants (Actual) | Interventional | 2010-02-28 | Terminated | |||
| Randomized Controlled Trial of Antibiotics in the Management of Children With Community-Acquired Skin and Soft Tissue Abscess Undergoing Incision and Drainage [NCT01498744] | 53 participants (Actual) | Interventional | 2010-02-28 | Terminated(stopped due to The study was closed due to poor enrollment and lack of interest.) | |||
| A Multi-Center, Double-Blind, Randomized, Vehicle-Controlled, Parallel-Group Study to Compare Perrigo Israel Pharmaceuticals, Ltd. Clindamycin Phosphate and Benzoyl Peroxide Topical Gel 1.2%/2.5% to Acanya® Topical Gel (Clindamycin Phosphate and Benzoyl P [NCT01796665] | Phase 3 | 1,180 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| The HYsteroscopic Miscarriage MaNagement (HYMMN) Trial [NCT04751500] | 149 participants (Actual) | Interventional | 2021-01-31 | Completed | |||
| Antibiotics During Intrauterine Balloon Tamponade Placement [NCT03478163] | Phase 4 | 11 participants (Actual) | Interventional | 2018-03-08 | Terminated(stopped due to Problems with recruitment) | ||
| Topical Clindamycin Salicylic Acid Preparation for the Treatment of Acne Vulgaris [NCT00361322] | Phase 1/Phase 2 | 40 participants | Interventional | 2005-04-30 | Completed | ||
| [NCT00377000] | Phase 4 | 60 participants | Interventional | 2005-11-30 | Completed | ||
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study to Determine the Therapeutic Equivalence of GDC 268 and Clindamycin Phosphate Topical Lotion, 1% in Subjects With Acne Vulgaris [NCT03717506] | Phase 3 | 1,236 participants (Actual) | Interventional | 2018-10-10 | Completed | ||
| A Multi-centre, Single-blind, Parallel Group, Clinical Evaluation of the Efficacy and Safety of Clindamycin 1% / Benzoyl Peroxide 3% and Azelaic Acid 20% in the Topical Treatment of Mild to Moderate Acne Vulgaris [NCT02058628] | Phase 4 | 222 participants (Actual) | Interventional | 2014-02-21 | Completed | ||
| Asymptomatic Colonization With S. Aureus After Therapy With Linezolid or Clindamycin for Acute S. Aureus Skin and Skin Structure Infections in Patients With Comorbid Conditions: A Randomized Trial [NCT01619410] | 25 participants (Actual) | Interventional | 2012-01-31 | Terminated(stopped due to slow accrual) | |||
| Antibiotic Profile of Pathogenic Bacteria Isolated From Postsurgical Site Infections in Public Hospitals in Northern Jordan [NCT05106803] | 24 participants (Actual) | Observational | 2019-08-01 | Completed | |||
| Postoperative Healthcare Utilization in Adenotonsillectomy Patients With Postoperative Antibiotic Administration Compared to Patients Without Antibiotic Administration [NCT01561703] | 58 participants (Actual) | Interventional | 2012-03-31 | Completed | |||
| Staphylococcus Aureus Network Adaptive Platform Trial [NCT05137119] | Phase 4 | 6,000 participants (Anticipated) | Interventional | 2022-02-16 | Recruiting | ||
| Comparison of Cephalexin Versus Clindamycin in the Empiric, Outpatient Treatment of Suspected Staphylococcal Cutaneous Infections in the Era of Community-associated Methicillin-resistant Staphylococcus Aureus (CA-MRSA) [NCT00352612] | Phase 4 | 200 participants (Actual) | Interventional | 2006-09-30 | Completed | ||
| Effect of Preoperative Single-dose Clindamycin on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Randomized Controlled Trial [NCT03033472] | Phase 2/Phase 3 | 72 participants (Anticipated) | Interventional | Not yet recruiting | |||
| A Multicentre, Randomized, Assessor-blind, Comparator-Controlled, Parallel-Group Clinical Trial to Establish the Efficacy and Safety of Duac™(1% Clindamycin as Clindamycin Phosphate and 5% Benzoyl Peroxide) Once Daily Gel Compared With Clindamycin Phospha [NCT01915732] | Phase 3 | 1,018 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Clinical and Radiographic Effects of Modified Minimally Invasive Surgical Technique With Clindamycin Augmented Platelet-rich Fibrin Versus Platelet-rich Fibrin Alone for Management of Periodontal Intrabony Defects: A Randomized Controlled Clinical Trial [NCT05177198] | 30 participants (Anticipated) | Interventional | 2022-03-31 | Not yet recruiting | |||
| Long-term StaphyloCoccus Aureus decolonizAtion in Patients on Home parenteRal nutRition: a randomIzed multicEnter tRial. [NCT03173053] | 63 participants (Actual) | Interventional | 2018-02-08 | Terminated(stopped due to Results interim-analysis) | |||
| The Fleming [FMTVDM] Directed CoVid-19 Treatment Protocol [NCT04349410] | Phase 2/Phase 3 | 1,800 participants (Actual) | Interventional | 2020-04-11 | Completed | ||
| Factors Affecting Medication Adherence to Topical Acne Medications: a Single-center, Prospective Study Evaluating the Adherence and Patient Satisfaction to Single and Multiple Topical Acne Medications [NCT05582434] | Early Phase 1 | 72 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
| Determining the Necessity for Postoperative Antibiotics After Salivary Stent Placement [NCT03333408] | Phase 4 | 40 participants (Anticipated) | Interventional | 2018-06-15 | Recruiting | ||
| Utility of Single-dose Oral Antibiotic Prophylaxis in Prevention of Surgical Site Infection in Dermatologic Surgery [NCT04580472] | Phase 4 | 1,600 participants (Anticipated) | Interventional | 2020-10-01 | Recruiting | ||
| The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures [NCT04198129] | Phase 1 | 174 participants (Anticipated) | Interventional | 2020-10-01 | Recruiting | ||
| Treatment of Bacterial Vaginosis in Early Pregnancy in Skaraborg County in Sweden and the Effect on Spontaneous Preterm Delivery [NCT02348463] | 540 participants (Actual) | Observational | 2007-01-31 | Completed | |||
| Phase 3 Study of IV to Oral 6-Day Tedizolid Phosphate Compared With 10-day Comparator in Subjects 12 to < 18 Years With cSSTI. [NCT02276482] | Phase 3 | 120 participants (Actual) | Interventional | 2015-03-25 | Completed | ||
| Antibiotic Irrigations for Intra-Abdominal Drains [NCT03476941] | Phase 2 | 50 participants (Anticipated) | Interventional | 2019-04-01 | Recruiting | ||
| Oral Antimicrobial Treatment vs. Outpatient Parenteral for Infective Endocarditis [NCT05398679] | Phase 4 | 360 participants (Anticipated) | Interventional | 2022-06-01 | Not yet recruiting | ||
| Prospective Cohort Study on Patients With Tedizolid Prolonged Therapy for Orthopedic Device Infections [NCT03378427] | 35 participants (Actual) | Interventional | 2018-08-28 | Completed | |||
| Continuous Versus Interrupted Use.of Vaginal Probiotic Plus Vaginal Clindamycin Cream for Bacterial Vaginosis a Randomized Controlled Study [NCT03234517] | Phase 2 | 200 participants (Anticipated) | Interventional | 2016-08-01 | Recruiting | ||
| Postoperative Antibiotics Following Primary and Secondary Breast Augmentation: A Double-Blinded, Randomized Trial [NCT04834310] | Phase 4 | 0 participants (Actual) | Interventional | 2021-04-01 | Withdrawn(stopped due to Do not have adequate funding to proceed with project.) | ||
| A Study to Evaluate the Efficacy and Safety of a Single Dose of an Injectable Antibiotic for the Prophylaxis of Surgical Site and Pleural Space Infection After Medical Thoracoscopy [NCT02446782] | Phase 4 | 100 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multiple-Site Study to Evaluate the Therapeutic Equivalence of a Generic Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Glenmark Generics, Ltd) to the Marketed Product BenzaClin® Topical Gel [NCT02465632] | Phase 3 | 1,100 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| Efficacy, Safety and Tolerability of Amoxicillin + Clavulanic Acid (875mg/125mg) Two Times a Day Compared to Clindamycin (150mg) Four Times a Day for 5-7 Days in Treatment of Acute Odontogenic Infection With or Without Abscess [NCT02141217] | Phase 4 | 472 participants (Actual) | Interventional | 2013-03-21 | Completed | ||
| [NCT02210689] | Phase 3 | 604 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Efficacy of Oral Antibiotic Therapy Compared to Intravenous Antibiotic Therapy for the Treatment of Diabetic Foot Osteomyelitis (CRO-OSTEOMYELITIS) [NCT02168816] | Phase 2 | 30 participants (Actual) | Interventional | 2014-03-19 | Terminated(stopped due to The study was stopped for feasibility (i.e., low recruitment)) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||