diltiazem has been researched along with Sensitivity and Specificity in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 13 (56.52) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Dong, Y; He, S; Li, C; Li, N; Yang, F | 1 |
| Dong, YM; Li, CL; Li, N; Lu, NW | 1 |
| Ferguson, PD; Jiang, Z; Smith, NW; Taylor, MR | 1 |
| Deng, B; Kang, Y; Li, L; Lu, H; Shi, A; Xu, Q | 1 |
| Bergman, AJ; Chodakewitz, J; Fraser, IP; Friedman, EJ; Larson, PJ; Li, CC; Stoch, SA; Wagner, JA; Wang, YH | 1 |
| Haemers, T; Remon, JP; Vergote, GJ; Verpoort, F; Vervaet, C | 1 |
| Koyama, T; Kukita, I; Matsuzaki, T; Nakasone, J; Sakanashi, M | 1 |
| Ashby, DT; Conditt, G; Dangas, G; Hirose, M | 1 |
| Stafilov, T; Stefova, M; Zendelovska, D | 1 |
| Li, K; Zhang, X; Zhao, F | 1 |
| Chen, YM; Chu, TS; Fang, CC; Lin, MT; Tsai, TJ; Yang, JY; Yen, CJ | 1 |
| Albu, F; David, V; Georgita, C; Medvedovici, A | 1 |
| Casley, WL; Ding, L; Yeung, P | 1 |
| Fu, Q; Huang, M; Li, JL; Liu, LS; Wang, CX; Wang, XD; Zhou, SF | 1 |
| Ascalone, V; Locatelli, M; Malavasi, B | 1 |
| Shigenobu, K; Takagi, N; Tanaka, H | 1 |
| Fraudeau, C; Luck, G; Mangani, F; Vérette, E | 1 |
| Devarajan, PV; Dhavse, VV | 1 |
| Asberg, A; Berg, KJ; Carlson, E; Christensen, H; Schram, L | 1 |
| Mishra, SK; Parija, SC; Raviprakash, V; Telang, AG; Varshney, VP | 1 |
| Bernecker, O; Hallström, S; Kröner, A; Mallinger, R; Ploner, M; Podesser, BK; Schirnhofer, J; Seitelberger, R | 1 |
| Chiap, P; Crommen, J; Hubert, P | 1 |
3 trial(s) available for diltiazem and Sensitivity and Specificity
| Article | Year |
|---|---|
Effect of different durations and formulations of diltiazem on the single-dose pharmacokinetics of midazolam: how long do we go?
Topics: Adult; Area Under Curve; Chemistry, Pharmaceutical; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diltiazem; Drug Interactions; Female; Humans; Ketoconazole; Male; Midazolam; Middle Aged; Sensitivity and Specificity; Young Adult | 2011 |
Nonlinear calibrations on the assay of dilitiazem and two of its metabolites from plasma samples by means of liquid chromatography and ESI/MS(2) detection: application to a bioequivalence study.
Topics: Adult; Calibration; Chromatography, High Pressure Liquid; Cross-Over Studies; Diltiazem; Female; Humans; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Therapeutic Equivalency | 2008 |
A simple and sensitive high-performance liquid chromatography assay of diltiazem and main metabolites in renal transplanted patients.
Topics: Adult; Aged; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cyclosporine; Diltiazem; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Sensitivity and Specificity | 1999 |
20 other study(ies) available for diltiazem and Sensitivity and Specificity
| Article | Year |
|---|---|
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Sensitive Analysis of Metoprolol Tartrate and Diltiazem Hydrochloride in Human Serum by Capillary Zone Electrophoresis Combining on Column Field-Amplified Sample Injection.
Topics: Diltiazem; Electrophoresis, Capillary; Humans; Limit of Detection; Linear Models; Metoprolol; Reproducibility of Results; Sensitivity and Specificity | 2021 |
A novel micellar per aqueous liquid chromatographic method for simultaneous determination of diltiazem hydrochloride, metoprolol tartrate and isosorbide mononitrate in human serum.
Topics: Chromatography, Liquid; Diltiazem; Drug Stability; Humans; Hydrogen-Ion Concentration; Isosorbide Dinitrate; Linear Models; Metoprolol; Micelles; Reproducibility of Results; Sensitivity and Specificity | 2014 |
Mixed-mode reversed-phase and ion-exchange monolithic columns for micro-HPLC.
Topics: Acrylates; Amitriptyline; Aniline Compounds; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Diltiazem; Hydrogen-Ion Concentration; Ketones; Methacrylates; Microchemistry; Molecular Structure; Particle Size; Phenols; Polycyclic Aromatic Hydrocarbons; Polymers; Porosity; Pyrazines; Quinine; Reproducibility of Results; Sensitivity and Specificity; Stearates; Surface Properties; Time Factors; Verapamil | 2008 |
Determination of the number of binding sites and binding constant between diltiazem hydrochloride and human serum albumin by ultrasonic microdialysis coupled with online capillary electrophoresis electrochemiluminescence.
Topics: Binding Sites; Diltiazem; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Luminescent Measurements; Microdialysis; Reproducibility of Results; Sensitivity and Specificity; Serum Albumin; Ultrasonics | 2010 |
Near-infrared FT-Raman spectroscopy as a rapid analytical tool for the determination of diltiazem hydrochloride in tablets.
Topics: Chromatography, High Pressure Liquid; Diltiazem; Sensitivity and Specificity; Spectroscopy, Near-Infrared; Spectrum Analysis, Raman; Tablets | 2002 |
Effects of diltiazem on in vitro cardiovascular actions of crude venom obtained from Okinawan box-jellyfish (Habu-kurage), Chiropsalmus quadrigatus.
Topics: Animals; Aorta, Thoracic; Cnidarian Venoms; Culture Techniques; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Male; Models, Animal; Muscle, Smooth, Vascular; Myocardial Contraction; Probability; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2002 |
Coronary artery spasm associated with a moderately severe atherosclerotic stenosis in the proximal LAD.
Topics: Adult; Aspirin; Atorvastatin; Cardiac Catheterization; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heptanoic Acids; Humans; Isosorbide; Pyrroles; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Ultrasonography, Interventional | 2002 |
High-performance liquid chromatographic determination of diltiazem in human plasma after solid-phase and liquid-liquid extraction.
Topics: Calibration; Chromatography, High Pressure Liquid; Diltiazem; Drug Stability; Humans; Reproducibility of Results; Sensitivity and Specificity | 2003 |
HPLC determination of diltiazem in human plasma and its application to pharmacokinetics in humans.
Topics: Adult; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Humans; Male; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Diltiazem suppresses collagen synthesis and IL-1beta-induced TGF-beta1 production on human peritoneal mesothelial cells.
Topics: Analysis of Variance; Blotting, Northern; Blotting, Western; Cells, Cultured; Collagen; Diltiazem; Epithelial Cells; Fibrosis; Humans; Interleukin-1; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Probability; Risk Assessment; Sensitivity and Specificity; Transforming Growth Factor beta | 2006 |
HPLC assay with UV detection for determination of RBC purine nucleotide concentrations and application for biomarker study in vivo.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biological Assay; Biomarkers; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Erythrocytes; Guanosine Triphosphate; Male; Physical Conditioning, Animal; Pilot Projects; Purine Nucleotides; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Reference Standards; Sensitivity and Specificity; Solid Phase Extraction; Species Specificity; Spectrophotometry, Ultraviolet | 2008 |
Rapid and simultaneous determination of tacrolimus (FK506) and diltiazem in human whole blood by liquid chromatography-tandem mass spectrometry: application to a clinical drug-drug interaction study.
Topics: Chromatography, High Pressure Liquid; Diltiazem; Drug Interactions; Humans; Immunosuppressive Agents; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tacrolimus; Tandem Mass Spectrometry | 2008 |
Determination of diltiazem and its main metabolites in human plasma by automated solid-phase extraction and high-performance liquid chromatography: a new method overcoming instability of the compounds and interference problems.
Topics: Acetylation; Autoanalysis; Chromatography, High Pressure Liquid; Diltiazem; Drug Stability; Humans; Methylation; Molecular Structure; Quality Control; Sensitivity and Specificity | 1994 |
Inotropic effects of ryanodine and calcium antagonists on embryonic and hatched chick myocardium.
Topics: Animals; Calcium; Calcium Channel Blockers; Chick Embryo; Chickens; Depression, Chemical; Diltiazem; Electric Stimulation; Heart; In Vitro Techniques; Manganese; Myocardial Contraction; Nicardipine; Ryanodine; Sensitivity and Specificity; Stimulation, Chemical | 1993 |
On-line column-switching high-performance liquid chromatography analysis of cardiovascular drugs in serum with automated sample clean-up and zone-cutting technique to perform chiral separation.
Topics: Cardiovascular Agents; Chromatography, High Pressure Liquid; Diltiazem; Lidocaine; Linear Models; Metoprolol; Online Systems; Oxprenolol; Pindolol; Sensitivity and Specificity; Stereoisomerism; Verapamil | 1997 |
High-performance thin-layer chromatographic determination of diltiazem hydrochloride as bulk drug and in pharmaceutical preparations.
Topics: Calcium Channel Blockers; Calibration; Chromatography, Thin Layer; Circadian Rhythm; Diltiazem; Drug Stability; Reproducibility of Results; Sensitivity and Specificity | 1998 |
Influence of hypothyroid state on 45Ca(2+) influx and sensitivity of rat uterus to nifedipine and diltiazem.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Diltiazem; Dose-Response Relationship, Drug; Female; Hypothyroidism; In Vitro Techniques; Methimazole; Muscle Contraction; Nifedipine; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Thyroxine; Triiodothyronine; Uterus | 2001 |
Diltiazem during reperfusion preserves high energy phosphates by protection of mitochondrial integrity.
Topics: Adenine Nucleotides; Analysis of Variance; Animals; Biopsy, Needle; Chromatography, High Pressure Liquid; Diltiazem; Disease Models, Animal; Female; Hemodynamics; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion; Phosphocreatine; Probability; Rabbits; Random Allocation; Reference Values; Reperfusion Injury; Sensitivity and Specificity | 2002 |
Automatic determination of diltiazem and desacetyldiltiazem in human plasma using liquid-solid extraction on disposable cartridges coupled to HPLC--Part I: Optimization of the HPLC system and method validation.
Topics: Automation; Chromatography, High Pressure Liquid; Diltiazem; Humans; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity | 1991 |