Page last updated: 2024-12-11
sr 4554
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
SR 4554: a fluorinated 2-nitroimidazole hypoxia probe; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 9882197 |
| SCHEMBL ID | 367605 |
| MeSH ID | M0250657 |
Synonyms (17)
| Synonym |
|---|
| n-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl)acetamide |
| 167648-73-9 |
| crc 94/17 |
| 9ja4q7568m , |
| 1h-imidazole-1-acetamide, 2-nitro-n-(3,3,3-trifluoro-2-hydroxypropyl)- |
| sr 4554 |
| unii-9ja4q7568m |
| sr-4554 |
| 2-(2-nitro-1h-imidazol-1-yl)-n-(3,3,3-trifluoro-2-hydroxypropyl)acetamide |
| SCHEMBL367605 |
| btlnrjmecftisr-uhfffaoysa-n |
| sr4554 |
| 2-(2-nitro-1h-imidazol-1-yl)-n-(3,3,3-trifluoro-2-hydroxypropyl)ethanimidic acid |
| DTXSID90937376 |
| Q27272622 |
| 2-(2-nitroimidazol-1-yl)-n-(3,3,3-trifluoro-2-hydroxypropyl)acetamide |
| AKOS040754081 |
Research Excerpts
Bioavailability
| Excerpt | Reference | Relevance |
|---|---|---|
| " As part of the pre-clinical development strategy, pharmacokinetic, bioavailability and biodistribution studies were performed in mice." | ( The pharmacokinetics, bioavailability and biodistribution in mice of a rationally designed 2-nitroimidazole hypoxia probe SR-4554. Aboagye, EO; Graham, MA; Kelson, AB; Lewis, AD; Ryan, KJ; Tracy, M; Workman, P, 1996) | 0.29 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (14)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (57.14) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 16.61
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (16.61) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 2 (14.29%) | 5.53% |
| Reviews | 4 (28.57%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (57.14%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||