Page last updated: 2024-11-11

sr 4554

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

SR 4554: a fluorinated 2-nitroimidazole hypoxia probe; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9882197
SCHEMBL ID367605
MeSH IDM0250657

Synonyms (17)

Synonym
n-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl)acetamide
167648-73-9
crc 94/17
9ja4q7568m ,
1h-imidazole-1-acetamide, 2-nitro-n-(3,3,3-trifluoro-2-hydroxypropyl)-
sr 4554
unii-9ja4q7568m
sr-4554
2-(2-nitro-1h-imidazol-1-yl)-n-(3,3,3-trifluoro-2-hydroxypropyl)acetamide
SCHEMBL367605
btlnrjmecftisr-uhfffaoysa-n
sr4554
2-(2-nitro-1h-imidazol-1-yl)-n-(3,3,3-trifluoro-2-hydroxypropyl)ethanimidic acid
DTXSID90937376
Q27272622
2-(2-nitroimidazol-1-yl)-n-(3,3,3-trifluoro-2-hydroxypropyl)acetamide
AKOS040754081

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" As part of the pre-clinical development strategy, pharmacokinetic, bioavailability and biodistribution studies were performed in mice."( The pharmacokinetics, bioavailability and biodistribution in mice of a rationally designed 2-nitroimidazole hypoxia probe SR-4554.
Aboagye, EO; Graham, MA; Kelson, AB; Lewis, AD; Ryan, KJ; Tracy, M; Workman, P, 1996
)
0.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (14)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's8 (57.14)18.2507
2000's6 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 16.61

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index16.61 (24.57)
Research Supply Index2.83 (2.92)
Research Growth Index4.26 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (16.61)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (14.29%)5.53%
Reviews4 (28.57%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (57.14%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]