cabozantinib profile

cabozantinib: a multikinase inhibitor [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

cabozantinib : A dicarboxylic acid diamide that is N-phenyl-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide in which the hydrogen at position 4 on the phenyl ring is substituted by a (6,7-dimethoxyquinolin-4-yl)oxy group. A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	25102847
CHEMBL ID	2105717
CHEBI ID	72317
SCHEMBL ID	360795
MeSH ID	M0558240

Synonym
HY-13016
FT-0664184
bdbm50021574
cabozantinib
chebi:72317 ,
849217-68-1
xl 184
bms-907351
bms 907351
XL-184 ,
D10062
cabozantinib (usan)
BCP9000470
n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
unii-1c39jw444g
xl184 cpd
1,1-cyclopropanedicarboxamide, n'-(4-((6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4- fluorophenyl)-
cabozantinib [usan:inn]
1c39jw444g ,
BCPP000308
xl-184,cabozantinib, bms-907351
NCGC00263164-01
n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-n'-(4-fluorophenyl)cyclopropane-1,1- dicarboxamide
cabozantinib [who-dd]
1,1-cyclopropanedicarboxamide, n'-(4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-n-(4-fluorophenyl)-
cabozantinib [inn]
cabozantinib [vandf]
cabozantinib [mi]
n-(4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
cabozantinib [usan]
1,1-cyclopropanedicarboxamide, n-(4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-n'-(4-fluorophenyl)-
CS-0278
S1119
xl-184 free base
CHEMBL2105717
bms-907351 free base
gtpl5887
n'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
cyclopropane-1,1-dicarboxylic acid[4-(6,7-dimethoxy-quinoline-4-yloxy)-phenyl]-amide (4-fluoro-phenyl)-amide
n-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-n'-(4 fluorophenyl)cyclopropane-1,1-dicarboxamide
ONIQOQHATWINJY-UHFFFAOYSA-N
cyclopropane-1,1-dicarboxylic acid [4-(6,7-dimethoxy-quinoline-4-yloxy)-phenyl]-amide(4-fluoro-phenyl)-amide
n-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
DTXSID10233968 ,
SCHEMBL360795
cabozantinib (xl184, bms-907351)
AKOS025142112
n-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
AC-25082
AB01565831_02
xl-184 free base (cabozantinib)
J-523016
EX-A075
SR-01000941569-1
sr-01000941569
HMS3654G06
mfcd20926324
NCGC00263164-14
SW218093-3
xl-184 (cabozantinib,bms907351)
DB08875
AS-16277
BCP02591
Q795057
BRD-K51544265-001-01-8
SB20062
CCG-264678
NCGC00263164-17
cabozantinib (free base)
849217-68-1 (free base)
1-n-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
n-[4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl]-n inverted exclamation mark -(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
SY097158
nsc-800066
nsc800066
nsc761068
nsc-761068
cabozantinib (bms-907351)
carbozantinib
l01xe26
cabozantinibum
n-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
dtxcid40156459

Excerpt	Reference	Relevance
"Cabozantinib (XL184) is a small-molecule kinase inhibitor with potent activity toward MET and VEGF receptor 2 (VEGFR2), as well as a number of other receptor tyrosine kinases that have also been implicated in tumor pathobiology, including RET, KIT, AXL, and FLT3."	( Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Bentzien, F; Cancilla, B; Chen, J; Chou, YC; Chu, F; Engst, S; Joly, AH; Laird, AD; Lee, L; Lesch, J; Orf, J; Qian, F; Shi, Y; Tan, J; Yakes, FM; Yamaguchi, K; You, A; Yu, P, 2011)	2.53
"Cabozantinib (CAB) is a receptor tyrosine kinase inhibitor with activity against MET, VEGFR2, and AXL, among others. "	( [Pharmacological properties and clinical outcomes of the anti-cancer drug, cabozantinib (CABOMETYX Hara, T; Osaka, T; Yamaguchi, N, 2021)	2.29
"Cabozantinib is a potent inhibitor of tyrosine kinase receptor that plays key role in tumor pathogenesis. "	( Characterization of the metabolite of cabozantinib generated from liver microsomes and hepatocytes by ultra-high performance liquid chromatography coupled to quadrupole/orbitrap high resolution mass spectrometry. Chang, J; Chen, H; Chen, J; Chen, W; Liu, L; Liu, Q; Sun, X; Wang, X; Wu, X; Xu, Z; Zhang, J, 2021)	2.34
"Cabozantinib is an oral small molecule tyrosine kinase inhibitor that exhibits potent inhibitory activity against several receptor tyrosine kinases that are known to influence tumor growth, metastasis, and angiogenesis."	( CABOCOL-01 trial: a single-arm phase II study assessing safety and efficacy of Cabozantinib for advanced or metastatic cervical carcinoma after platinum treatment failure. Bonnet, I; Brachet, PE; Castera, M; Clarisse, B; Coquan, E; Joly, F; Leconte, A; Lelaidier, A; Lequesne, J; Licaj, I; Meriaux, E, 2021)	1.57
"Cabozantinib is a promising drug for patients with advanced/metastatic cervical cancer where few therapeutics options are available after failure to platinum-based regimen metastatic CC. "	( CABOCOL-01 trial: a single-arm phase II study assessing safety and efficacy of Cabozantinib for advanced or metastatic cervical carcinoma after platinum treatment failure. Bonnet, I; Brachet, PE; Castera, M; Clarisse, B; Coquan, E; Joly, F; Leconte, A; Lelaidier, A; Lequesne, J; Licaj, I; Meriaux, E, 2021)	2.29
"Cabozantinib is a multi-target small molecule tyrosine kinase inhibitor and has been approved for the treatment of multiple malignant solid tumors."	( Cabozantinib ameliorates lipopolysaccharide-induced lung inflammation and bleomycin--induced early pulmonary fibrosis in mice. Cui, Y; Gu, J; Huang, H; Li, S; Li, X; Liang, J; Liu, R; Ma, L; Wei, Y; Yang, C; Zhou, H, 2021)	2.79
"Cabozantinib is a receptor tyrosine kinase (RTK) inhibitor, already approved for the treatment of non-skin-related cancers."	( Cabozantinib Is Effective in Melanoma Brain Metastasis Cell Lines and Affects Key Signaling Pathways. Aasen, SN; Bjørnstad, OV; Hoang, T; Mannsåker, TA; Parajuli, H; Sundstrøm, T; Thorsen, FA, 2021)	2.79
"Cabozantinib is an inhibitor of multiple tyrosine kinases, including AXL, MET and VEGF receptors. "	( CaboPoint: a phase II study of cabozantinib as second-line treatment in patients with metastatic renal cell carcinoma. Albiges, L; Grünwald, V; Guemas, E; Perol, D; Schmidinger, M; Taguieva-Pioger, N, 2022)	2.45
"Cabozantinib is an oral treatment approved for use in some patients with advanced RCC, including those with clear cell disease."	( CaboPoint: a phase II study of cabozantinib as second-line treatment in patients with metastatic renal cell carcinoma. Albiges, L; Grünwald, V; Guemas, E; Perol, D; Schmidinger, M; Taguieva-Pioger, N, 2022)	1.73
"Cabozantinib is a multi TKI used for the treatment of mRCC in the first- and second-line setting."	( Cabozantinib in the treatment of metastatic renal cell carcinoma - final data analysis from four oncology centers in the Czech Republic. Bartoš, J; Brom, O; Büchler, T; Dvořák, J; Melichar, B; Poprach, A; Richter, I; Rozsypalová, A; Šámal, V; Študentová, H; Zemánková, A, 2021)	2.79
"Cabozantinib is a dual inhibitor of MET and VEGFR2."	( Dual blockade of MET and VEGFR2 signaling pathways as a potential therapeutic maneuver for peritoneal carcinomatosis in scirrhous gastric cancer. Kasai, S; Kawashima, A; Kuwayama, N; Matsumoto, K; Matsushima, K; Motoo, Y; Yano, S; Yasumoto, K, 2022)	1.44
"Cabozantinib is expected to be an effective treatment due to its activity against many protein kinases, including MET and AXL which are not inhibited by sorafenib."	( Phase II clinical trial of cabozantinib for the treatment of recurrent hepatocellular carcinoma after liver transplantation. Azhie, A; Bhat, M; Grant, RC; Herman, M; Knox, JJ; Wang, L, 2022)	1.74
"Cabozantinib is a tyrosine kinase inhibitor with anti-tumor activity in kidney cancer. "	( The protective effects of cabozantinib against high glucose-induced damages in Tian, H; Wang, Q; Yan, J; Ye, H; Zhou, L, 2022)	2.46
"Cabozantinib is a multiple receptor tyrosine kinases inhibitor (TKI) approved to treat progressive, metastatic medullary thyroid cancer, advanced renal cell carcinoma, and hepatocellular carcinoma. "	( Cabozantinib Carries the Risk of Drug-Drug Interactions Jiang, L; Liu, Y; Lv, X; Wang, X; Wang, Z; Yin, H, 2022)	3.61
"Cabozantinib monotherapy is an option for treatment of advanced renal cell carcinoma (RCC). "	( Electronic patient-reported outcome (e-PRO) monitoring for adverse event management during cabozantinib treatment in patients with advanced renal cell carcinoma: protocol for a three-arm, randomised, multicentre phase II trial (e-PRO vs paper-PRO or usual Fujii, Y; Iizumi, S; Kimura, G; Kitamura, H; Nagashima, Y; Osaka, T; Osawa, T; Shinohara, N; Tsubouchi, R, 2023)	2.57
"Cabozantinib is an inhibitor of multiple tyrosine kinases with a pivotal role in NET pathogenesis, including c-MET and Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)."	( Assessing the safety and activity of cabozantinib combined with lanreotide in gastroenteropancreatic and thoracic neuroendocrine tumors: rationale and protocol of the phase II LOLA trial. Amoroso, V; Brizzi, MP; Campana, D; Cascella, T; Coppa, J; Corti, F; de Braud, F; Di Bartolomeo, M; Giuffrida, D; Leporati, R; Milione, M; Oldani, S; Panzuto, F; Porcu, L; Prinzi, N; Pulice, I; Pusceddu, S; Randon, G; Scotto, G; Spreafico, C; Stocchetti, BL, 2023)	1.9
"Cabozantinib is a tyrosine kinase inhibitor (TKI) whose targets include MET, AXL, and VEGFR2."	( Cabozantinib in Combination with Immunotherapy for Advanced Renal Cell Carcinoma and Urothelial Carcinoma: Rationale and Clinical Evidence. Bergerot, P; Lamb, P; Pal, SK; Wang, E, 2019)	2.68
"Cabozantinib (CABO) is an inhibitor of c-MET, vascular endothelial growth factor receptor 2, AXL, and RET and approved for advanced kidney cancer, liver carcinoma after previous sorafenib, and medullary thyroid carcinoma."	( Objective Response and Prolonged Disease Control of Advanced Adrenocortical Carcinoma with Cabozantinib. Fassnacht, M; Habra, MA; Jimenez, C; Kroiss, M; Kurlbaum, M; Lapa, C; Megerle, F; Quinkler, M; Scherf-Clavel, O; Wendler, J; Zimmermann, S, 2020)	1.5
"Cabozantinib is a novel multi-target tyrosine kinase inhibitor recently approved in metastatic renal cell carcinoma (mRCC) leading to frequent severe toxicities requiring empirical dose reduction. "	( A simple and rapid liquid chromatography-mass spectrometry method to assay cabozantinib in plasma: Application to therapeutic drug monitoring in patients with renal cell carcinoma. Ciccolini, J; Deville, JL; Ferrer, F; Giocanti, M; Gravis, G; Lacarelle, B; Solas, C, 2020)	2.23
"Cabozantinib is an Food and Drug Administration approved multitargeted tyrosine kinase inhibitor for select adult malignancies with preclinical data suggesting efficacy against neuroblastoma."	( Cabozantinib for relapsed neuroblastoma: Single institution case series. Perisa, MP; Ranalli, MA; Shah, N; Skeens, M; Storey, M; Streby, KA, 2020)	2.72
"Cabozantinib is a strong multi-inhibitor of receptor tyrosine kinases approved for renal cell carcinoma that could be useful also for the treatment of HCC."	( Cabozantinib as a second-line treatment option in hepatocellular carcinoma. Bagby, S; Casadei-Gardini, A; D'Angelo, A; Roviello, G; Sobhani, N, 2020)	2.72
"Cabozantinib is an oral tyrosine kinase inhibitor that targets VEGFR, MET and the TAM (TYRO3, AXL, MER) family of kinase receptors. "	( Cabozantinib in combination with atezolizumab versus sorafenib in treatment-naive advanced hepatocellular carcinoma: COSMIC-312 Phase III study design. Benzaghou, F; Cheng, AL; Hazra, S; Kelley, RK; Rimassa, L; W Oliver, J; Yau, T, 2020)	3.44
"Cabozantinib is a tyrosine kinase inhibitor currently approved for advanced renal cell, hepatocellular, and medullary thyroid carcinoma."	( Cabozantinib as an emerging treatment for sarcoma. Blay, JY; Ray-Coquard, I; Schöffski, P, 2020)	2.72
"Cabozantinib is a multikinase inhibitor of MET, VEGFR, AXL, and RET, which also has an effect on the tumour immune microenvironment by decreasing regulatory T cells and myeloid-derived suppressor cells. "	( Cabozantinib in patients with platinum-refractory metastatic urothelial carcinoma: an open-label, single-centre, phase 2 trial. Agarwal, PK; Alarcon, SV; Allette, K; Apolo, AB; Bottaro, DP; Cao, L; Cordes, LM; Costello, R; Dahut, WL; Davarpanah, NN; Dawson, NA; De Silva, D; Figg, WD; Folio, LR; Gulley, JL; Lee, MJ; Lee, MM; Lee, S; Lin, J; Lindenberg, L; Merino, MJ; Nadal, R; Ning, YM; Parnes, HL; Raffeld, M; Roy, A; Sissung, TM; Steinberg, SM; Tomita, Y; Trepel, JB; Wright, JJ; Yuno, A, 2020)	3.44
"Cabozantinib is an oral tyrosine kinase inhibitor (TKI) approved for the treatment of patients with advanced renal cell carcinoma (RCC) at a dose of 60 mg/day. "	( Exposure-response modeling of cabozantinib in patients with renal cell carcinoma: Implications for patient care. Benzaghou, F; Castellano, D; Clary, DO; Jonasch, E; Nguyen, L; Pablo Maroto, J; Taguieva, N, 2020)	2.29
"Cabozantinib is an oral multikinase inhibitor whose targets include vascular endothelial growth factor receptors, MET, and the TAM family of kinases (TYRO3, AXL, MER). "	( Management of Adverse Events Associated with Cabozantinib Treatment in Patients with Advanced Hepatocellular Carcinoma. Damicis, L; Darling, JO; Mindo, M; Schwartz, G, 2020)	2.26
"Cabozantinib is a tyrosine kinase inhibitor (TKI) approved for the treatment of medullary thyroid cancer, renal cell carcinoma and hepatocellular carcinoma, and is currently in clinical trials for the treatment of prostate cancer and others. "	( Preclinical evaluation of [ Attili, B; Bormans, G; Celen, S; Doumont, G; Klaveness, J; Lien, VT; Nuruddin, S; Olberg, DE; Van Simaeys, G, 2021)	2.06
"Cabozantinib is an inhibitor of multiple kinases, including vascular endothelial growth factor receptor 2 (VEGFR2) and c-MET, and may delay or reverse anti-EGFR resistance."	( Cabozantinib and Panitumumab for RAS Wild-Type Metastatic Colorectal Cancer. Altomare, IP; Blobe, GC; Bolch, E; Chang, DZ; Haley, S; Hatch, AJ; Hsu, SD; Hurwitz, HI; Jia, J; Morse, MA; Moyer, AN; Niedzwiecki, D; Nixon, AB; Rushing, CN; Sherrill, GB; Strickler, JH; Uronis, HE; Webb, R; Wells, JL; Zafar, SY, 2021)	2.79
"Cabozantinib is an oral tyrosine kinase inhibitor that is approved for the treatment of metastatic renal cell carcinoma (mRCC). "	( The Effect of Concomitant Proton Pump Inhibitor and Cabozantinib on the Outcomes of Patients with Metastatic Renal Cell Carcinoma. Albiges, L; Alves Costa Silva, C; Auclin, E; Benchimoll-Zouari, A; Cerbone, L; Colomba, E; Combarel, D; Escudier, B; Flippot, R; Geraud, A; Guida, A; Mir, O; Paci, A; Rassy, E, 2021)	2.31
"Cabozantinib is an effective treatment for metastatic renal cell carcinoma (mRCC). "	( Novel risk scoring system for metastatic renal cell carcinoma patients treated with cabozantinib. Bilen, MA; Carthon, BC; Caulfield, S; Goldman, JM; Harris, WB; Hitron, EE; Kline, MR; Kucuk, O; Liu, Y; Martini, DJ; Master, VA; Russler, GA; Shabto, JM; Yantorni, L, 2021)	2.29
"Cabozantinib is a potent tyrosine kinase inhibitor with multiple targets including MET, VEGFR2, RET, KIT, and FLT3. "	( Cabozantinib promotes erythroid differentiation in K562 erythroleukemia cells through global changes in gene expression and JNK activation. Chen, CY; Chien, HF; Fu, YH; Lai, ZS; Lin, LI; Ou, DL; Shen, CJ; Su, KW; Tien, HF; Yang, YR, 2022)	3.61
"Cabozantinib is an oral tyrosine kinase inhibitor that inhibits several RTKs involved in tumorigenesis, and is approved for the treatment of patients with progressive metastatic medullary thyroid cancer, advanced renal cell carcinoma, and hepatocellular carcinoma that has been previously treated with sorafenib."	( Antitumor effects of the multi-target tyrosine kinase inhibitor cabozantinib: a comprehensive review of the preclinical evidence. Colonna, V; Iacovelli, R; Klinz, S; Mauri, G; Nuti, M; Santoni, M, 2021)	1.58
"Cabozantinib is a multi-kinase inhibitor that targets MET, AXL, and VEGFR2, and may synergize with EGFR inhibition in NSCLC. "	( A phase Ib/II study of cabozantinib (XL184) with or without erlotinib in patients with non-small cell lung cancer. Engelman, J; Gettinger, S; Jänne, PA; Lara, PN; Leach, J; Miles, DR; Subramaniam, DS; Wakelee, HA; Wax, M; West, H; Yaron, Y, 2017)	2.21
"Cabozantinib is a small molecule tyrosine kinase inhibitor against the oncoprotein MET."	( Clinical efficacy of cabozantinib in two pediatric patients with recurrent renal cell carcinoma. Ranalli, M; Shah, N; Wedekind, MF, 2017)	1.5
"Cabozantinib is an oral multiple tyrosine kinase receptor inhibitor (ITK): VEGFR2, c-MET and RET. "	( [Cabozantinib: Mechanism of action, efficacy and indications]. Cochin, V; Godbert, Y; Gross-Goupil, M; Le Moulec, S; Ravaud, A, 2017)	2.81
"Cabozantinib is a small molecule tyrosine kinase inhibitor that initially showed activity in medullary thyroid cancer and was recently approved by the Food and Drug Administration for the treatment of metastatic renal cell carcinoma after progression on first line therapy. "	( Cabozantinib for the treatment of kidney cancer. Abdelaziz, A; Vaishampayan, U, 2017)	3.34
"Cabozantinib is a novel multikinase inhibitor with activity against vascular endothelial growth factor receptor (VEGFR), proto-oncogene tyrosine-protein kinase receptor Ret and other kinases that recently joined this impressive list of approved agents."	( Cabozantinib use in renal cell carcinoma. Bowles, DW; Johnson, AT; Kessler, ER; Mathur, S; Neuwelt, AJ, 2017)	2.62
"Cabozantinib is an oral multikinase inhibitor targeting MET in addition to VEGFR and is approved for medullary thyroid cancer."	( Cabozantinib As Salvage Therapy for Patients With Tyrosine Kinase Inhibitor-Refractory Differentiated Thyroid Cancer: Results of a Multicenter Phase II International Thyroid Oncology Group Trial. Cabanillas, ME; de Souza, JA; Geyer, S; Liu, SV; Menefee, ME; Shah, K; Shah, MH; Wirth, LJ; Wright, J, 2017)	2.62
"Cabozantinib is a tyrosine kinase inhibitor with activity against vascular endothelial growth factor receptor 2 (VEGFR2) and MET that has demonstrated clinical activity in advanced solid tumors. "	( Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients naive to antiangiogenic therapy. Chamberlain, M; Cloughesy, TF; de Groot, J; Desjardins, A; Drappatz, J; Holland, J; Mikkelsen, T; Ping, J; Prados, MD; Reardon, DA; Schiff, D; Weitzman, R; Wen, PY, 2018)	2.26
"Cabozantinib is a potent, multitarget inhibitor of MET and vascular endothelial growth factor receptor 2 (VEGFR2). "	( Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy. Chamberlain, M; Cloughesy, TF; de Groot, J; Desjardins, A; Drappatz, J; Holland, J; Mikkelsen, T; Ping, J; Prados, MD; Reardon, DA; Schiff, D; Weitzman, R; Wen, PY, 2018)	2.26
"Cabozantinib is an inhibitor of tyrosine kinases, including MET, vascular endothelial growth factor receptor, AXL and RET. "	( Phase II randomised discontinuation trial of cabozantinib in patients with advanced solid tumours. Daud, A; Gordon, M; Kurzrock, R; Lee, Y; Scheffold, C; Schöffski, P; Shapiro, GI; Smith, DC; Vogelzang, NJ, 2017)	2.16
"Cabozantinib is a multikinase inhibitor targeting VEGF receptor (VEGFR) 2, mesenchymal-epithelial transition receptor, and "anexelekto" receptor tyrosine kinase."	( Management of Adverse Events Associated with Cabozantinib Therapy in Renal Cell Carcinoma. Danesi, R; Schmidinger, M, 2018)	1.46
"Cabozantinib is an oral small-molecule multitargeted tyrosine kinase inhibitor (TKI) that may confer an advantage over other TKIs that target a single receptor. "	( Cabozantinib: A Multitargeted Oral Tyrosine Kinase Inhibitor. Fancher, KM; Markowitz, JN, 2018)	3.37
"Cabozantinib is a multikinase inhibitor approved for the treatment of metastatic medullary thyroid cancer and advanced renal cell carcinoma (RCC) in patients who have received prior anti-angiogenic therapy. "	( Cabozantinib-induced serum creatine kinase elevation and musculoskeletal complaints. Crona, DJ; Stump, SE; Whang, YE, 2018)	3.37
"Cabozantinib is a receptor tyrosine kinase inhibitor (TKI) with activity against a broad range of targets, including MET, RET, AXL, VEGFR2, FLT3, and c-KIT. "	( Cabozantinib: Multi-kinase Inhibitor of MET, AXL, RET, and VEGFR2. Grüllich, C, )	3.02
"Cabozantinib is a multitargeted tyrosine kinase inhibitor that demonstrated remarkable responses on bone scan in metastatic prostate cancer. "	( Biomarkers and Bone Imaging Dynamics Associated with Clinical Outcomes of Oral Cabozantinib Therapy in Metastatic Castrate-Resistant Prostate Cancer. Boerner, J; Dobson, KC; Fontana, JA; Heath, EI; Heilbrun, LK; Lawhorn-Crews, JM; Podgorski, I; Shields, AF; Smith, DW; Stark, K; Vaishampayan, UN, 2019)	2.18
"Cabozantinib is a receptor tyrosine kinases inhibitor that targets MET (c-MET), VEGF receptor 2 (VEGFR2), RET, AXL, KIT, FLT-3, and TIE-2 and previously showed promising single agent activity in recurrent ovarian cancer."	( A randomized phase II study of cabozantinib versus weekly paclitaxel in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study. Aghajanian, C; Bender, DP; Carlson, JW; Crane, EK; Darus, CJ; Makker, V; Mannel, RS; Matulonis, UA; Mutch, DG; Sill, MW, 2019)	2.24
"Cabozantinib is a multitargeted tyrosine kinase inhibitor, with activity against vascular endothelial growth factor receptor, as well as MET, RET, and AXL. "	( Reversible Cabozantinib-Induced Cardiomyopathy. Alhussein, M; Hotte, SJ; Leong, DP, 2019)	2.35
"Cabozantinib is an approved treatment for metastatic renal cell carcinoma (mRCC). "	( Real-world Experience of Cabozantinib as Second- or Subsequent Line Treatment in Patients With Metastatic Renal Cell Carcinoma: Data From the Polish Managed Access Program. Bodnar, L; Chrom, P; Kopczyńska, A; Tomczak, P; Wieczorek-Rutkowska, M; Żołnierek, J, 2019)	2.26
"Cabozantinib is a multi-kinase inhibitor targeting MET, AXL, and VEGFR2, and has been approved for use in multiple malignancies. "	( Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway. Qu, B; Qu, H; Yang, S; Yin, X; Zhang, X; Zhao, H, 2020)	3.44
"Cabozantinib is a multityrosine kinase inhibitor and has a wide range of applications in the clinic, whose metabolism is predominately dependent on CYP3A4. "	( Characterization of Genetic Variation in CYP3A4 on the Metabolism of Cabozantinib in Vitro. Cai, JP; Hu, GX; Li, YH; Lin, QM; Lu, XR; Pang, NH; Wang, R; Xu, RA, 2019)	2.19
"Cabozantinib is an oral MET/VEGFR2 inhibitor. "	( A dose-ranging study of cabozantinib in men with castration-resistant prostate cancer and bone metastases. Goldin, JG; Gurski, CA; Haber, DA; Lee, RJ; Maheswaran, S; Michaelson, MD; Miyamoto, DT; Rothenberg, SM; Saylor, PJ; Smas, ME; Smith, MR; Xie, W, 2013)	2.14
"Cabozantinib is a potent inhibitor of MET, RET, and vascular endothelial factor receptor 2 (VEGFR2), as well as other tyrosine kinases that have been implicated in tumor development and progression."	( In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancer. Bautista, R; Bentzien, F; Cancilla, B; Chu, F; Engst, S; Gibson, A; Goon, L; Heald, N; Huang, D; Joly, AH; Lamb, P; Shi, Y; Vysotskaia, V; Yakes, FM; Yu, P; Zhang, W; Zhao, L; Zuzow, M, 2013)	1.39
"Cabozantinib is a potent inhibitor of RET and prevalent mutationally activated forms of RET known to be associated with MTC, and effectively inhibits the growth of a MTC tumor cell model in vitro and in vivo."	( In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancer. Bautista, R; Bentzien, F; Cancilla, B; Chu, F; Engst, S; Gibson, A; Goon, L; Heald, N; Huang, D; Joly, AH; Lamb, P; Shi, Y; Vysotskaia, V; Yakes, FM; Yu, P; Zhang, W; Zhao, L; Zuzow, M, 2013)	2.11
"Cabozantinib (XL184) is an oral multiple receptor tyrosine kinase inhibitor manufactured by Exelixis Inc., CA, USA. "	( Cabozantinib (XL184) for the treatment of locally advanced or metastatic progressive medullary thyroid cancer. Cappagli, V; Elisei, R; Viola, D, 2013)	3.28
"Cabozantinib is an inhibitor of multiple receptor tyrosine kinases, including MET and VEGFR2. "	( Cabozantinib inhibits growth of androgen-sensitive and castration-resistant prostate cancer and affects bone remodeling. Aftab, DT; Brown, LG; Corey, E; Gross, TS; Gulati, R; Morrissey, C; Nguyen, HM; Ruppender, N; Schimmoller, F; Vessella, RL; Zhang, X, 2013)	3.28
"Cabozantinib is a novel TKI currently Food and Drug Administration approved for advanced medullary thyroid cancer and tested in clinical trials on solid tumors including prostate, liver, bladder, breast, and ovarian cancer."	( Cabozantinib-induced thyroid dysfunction: a review of two ongoing trials for metastatic bladder cancer and sarcoma. Apolo, AB; Celi, FS; del Rivero, J; Kummar, S; Madan, RA; Reynolds, J; Shawker, T; Yavuz, S, 2014)	2.57
"Cabozantinib is a receptor tyrosine kinase inhibitor with activity against MET, VEGFR2, FLT3, c-KIT, and RET. "	( Cabozantinib: a MET, RET, and VEGFR2 tyrosine kinase inhibitor. Grüllich, C, 2014)	3.29
"Cabozantinib (Cometriq(®)) is an orally administered small molecule inhibitor of multiple tyrosine kinase receptors, including those involved in the pathogenesis of medullary thyroid cancer (MTC) [i.e. "	( Cabozantinib: a review of its use in patients with medullary thyroid cancer. Hoy, SM, 2014)	3.29
"Cabozantinib S-malate is a vascular endothelial growth factor receptor 2, c-MET, and RET multitargeted tyrosine kinase inhibitor that has antiangiogenic and antitumorigenic properties with potential efficacy for the treatment of several cancers. "	( Cutaneous adverse effects associated with the tyrosine-kinase inhibitor cabozantinib. Apolo, AB; Cowen, EW; Dahut, WL; DiGiovanna, JJ; Keen, CM; Nanda, S; Parnes, HL; Zuo, RC, 2015)	2.09
"Cabozantinib (XL184) is a novel small molecule inhibitor of receptor tyrosine kinases (RTKs) targeted at mesenchymal-epithelial transition factor (MET). "	( Pharmacokinetics and tissue distribution model of cabozantinib in rat determined by UPLC-MS/MS. Chen, H; Hu, L; Lin, F; Ma, J; Wang, S; Wang, X; Wen, C; Zhang, Q, 2015)	2.11
"Cabozantinib is a small-molecule tyrosine kinase inhibitor that has been approved for the treatment of patients with progressive, metastatic medullary thyroid cancer. "	( Pharmacokinetic (PK) drug interaction studies of cabozantinib: Effect of CYP3A inducer rifampin and inhibitor ketoconazole on cabozantinib plasma PK and effect of cabozantinib on CYP2C8 probe substrate rosiglitazone plasma PK. Benrimoh, N; Engel, C; Holland, J; Lacy, S; Miles, D; Nguyen, L; O'Reilly, T, 2015)	2.11
"Cabozantinib is a small molecule tyrosine kinase inhibitor that has been approved for the treatment of patients with progressive, metastatic medullary thyroid cancer. "	( Evaluation of the effect of food and gastric pH on the single-dose pharmacokinetics of cabozantinib in healthy adult subjects. Armas, D; Grenier, J; Holland, J; Laberge, MK; Lacy, S; Mamelok, R; Nguyen, L; Swearingen, D, 2015)	2.08
"Cabozantinib is a tyrosine kinase inhibitor approved in the USA and EU for the treatment of patients with progressive, metastatic medullary thyroid cancer (MTC). "	( Population Pharmacokinetic Model of Cabozantinib in Patients with Medullary Thyroid Carcinoma and Its Application to an Exposure-Response Analysis. Jumbe, NL; Lacy, S; Miles, D; Nguyen, L, 2016)	2.15
"Cabozantinib is an oral once-daily multitarget tyrosine kinase inhibitor of MET, VEGFR2, RET, acting against KIT, AXL, FLT3 and Tie-2. "	( Cabozantinib in Thyroid Cancer. Antonelli, A; Benvenga, S; Di Bari, F; Fallahi, P; Ferrari, SM; Materazzi, G; Miccoli, P, 2015)	3.3
"Cabozantinib is a multi-targeted tyrosine kinase inhibitor targeting vascular endothelial growth factor (VEGF) receptor (VEGFR)-2, MET (c-Met, also called hepatocyte growth factor (HGF) receptor), and other receptor tyrosine kinases. "	( 2ME2 inhibits the activated hypoxia-inducible pathways by cabozantinib and enhances its efficacy against medullary thyroid carcinoma. Dong, X; Jiang, H; Jiang, W; Jiang, X; Lin, H; Qiao, H; Sun, X; Zhu, H, 2016)	2.12
"Cabozantinib is an oral, small-molecule tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR) as well as MET and AXL, each of which has been implicated in the pathobiology of metastatic renal-cell carcinoma or in the development of resistance to antiangiogenic drugs. "	( Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma. Bjarnason, GA; Borgman-Hagey, A; Choueiri, TK; Donskov, F; Escudier, B; Géczi, L; Hammers, H; Heng, DY; Hessel, C; Hutson, TE; Kantoff, PW; Keam, B; Lee, JL; Mainwaring, PN; Maroto, P; Motzer, RJ; Peltola, K; Powles, T; Rini, BI; Roth, BJ; Scheffold, C; Schmidinger, M; Schwab, GM; Tannir, NM, 2015)	3.3
"Cabozantinib (XL-184) is a potent inhibitor of MET, VEGFR 2/KDR, RET and other receptor tyrosine kinases, such as KIT, AXL and FLT3. "	( Cabozantinib for the treatment of progressive metastatic medullary thyroid cancer. Jarzab, B; Krajewska, J; Olczyk, T, 2016)	3.32
"Cabozantinib is an orally available inhibitor of tyrosine kinases including VEGFR2 and c-MET. "	( Changes in plasma biomarkers following treatment with cabozantinib in metastatic castration-resistant prostate cancer: a post hoc analysis of an extension cohort of a phase II trial. Aftab, DT; Azad, AA; Berger, R; Chi, KN; Joshua, AM; Khoja, L; Laird, AD; Leibowitz-Amit, R; Pintilie, M, 2016)	2.13
"Cabozantinib is a tyrosine kinase inhibitor approved for the treatment of patients with progressive, metastatic medullary thyroid cancer. "	( Effect of Renal and Hepatic Impairment on the Pharmacokinetics of Cabozantinib. Benrimoh, N; Ciric, S; Gavis, E; Heuman, DM; Holland, J; Lacy, S; Mamelok, R; Marbury, T; Nguyen, L; Preston, RA; Ramies, D, 2016)	2.11
"Cabozantinib is an oral multikinase inhibitor that exhibits anti-tumor activity in several cancers. "	( Cabozantinib is selectively cytotoxic in acute myeloid leukemia cells with FLT3-internal tandem duplication (FLT3-ITD). Chen, CY; Hou, HA; Hu, CY; Liao, HA; Lin, LI; Lu, JW; Ou, DL; Tien, HF; Wang, AN, 2016)	3.32
"Cabozantinib (XL184) is an oral inhibitor of multiplereceptor tyrosine kinases including mesenchymal-epithelial transition factor (MET) and vascular endothelial growth factor receptor 2 (VEGFR2). "	( Incidence and risk of hypertension associated with cabozantinib in cancer patients: a systematic review and meta-analysis. Shao, Y; Wang, K; Zhang, X, 2016)	2.13
"Cabozantinib is an oral inhibitor of tyrosine kinases including MET, VEGFR, and AXL. "	( Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial. Aftab, DT; Agarwal, N; Choueiri, TK; Donskov, F; Escudier, B; Hammers, HJ; Heng, DYC; Hessel, C; Hutson, TE; Lee, JL; Mainwaring, PN; McDermott, DF; Motzer, RJ; Pal, S; Peltola, K; Powles, T; Rini, BI; Roth, BJ; Scheffold, C; Schmidinger, M; Schwab, G; Sternberg, CN; Tannir, NM, 2016)	3.32
"Cabozantinib is an inhibitor of kinases, including MET and vascular endothelial growth factor receptors, and has shown activity in men with previously treated metastatic castration-resistant prostate cancer (mCRPC). "	( Phase III Study of Cabozantinib in Previously Treated Metastatic Castration-Resistant Prostate Cancer: COMET-1. Bergman, A; Bögemann, M; Cruciani, G; De Bono, J; De Giorgi, U; De Wit, R; Feyerabend, S; Fizazi, K; Hessel, C; Hoelzer, W; Houédé, N; Hussain, S; Krainer, M; Lam, E; Le Moulec, S; Mainwaring, P; Miller, K; Oudard, S; Polikoff, J; Ramies, D; Saad, F; Smith, M; Stenzl, A; Sternberg, C; Thiery-Vuillemin, A; Weitzman, A, 2016)	2.21
"Cabozantinib is a multikinase inhibitor with activity against RET that produced a 10% overall response in unselected patients with lung cancers."	( Cabozantinib in patients with advanced RET-rearranged non-small-cell lung cancer: an open-label, single-centre, phase 2, single-arm trial. Albano, M; Arcila, M; Drilon, A; Ginsberg, MS; Kris, MG; Ladanyi, M; Montecalvo, J; Ni, A; Plodkowski, A; Rekhtman, N; Riely, GJ; Rudin, CM; Smith, RS; Somwar, R; Van Voorthuysen, M; Wang, L, 2016)	2.6
"Cabozantinib (XL184) is a small molecule tyrosine kinase receptor inhibitor, which targets c-Met and VEGFR2. "	( Modulating the function of ATP-binding cassette subfamily G member 2 (ABCG2) with inhibitor cabozantinib. Barbuti, AM; Chen, ZS; Wang, YJ; Wen, AW; Wurpel, JND; Yu, XY; Zhang, GN; Zhang, YK; Zhu, XJ, 2017)	2.12
"Cabozantinib is an oral multitargeted TKI with activity against multiple receptors including RET, vascular endothelial growth factor receptor type 2 (VEGFR2), and MET that has been evaluated in MTC in the preclinical and clinical arenas."	( Cabozantinib for the treatment of advanced medullary thyroid cancer. Brown, RL; Cohen, EE; Nagilla, M, 2012)	2.54
"Cabozantinib (XL184) is an orally bioavailable tyrosine kinase inhibitor with activity against MET and vascular endothelial growth factor receptor 2. "	( Cabozantinib in patients with advanced prostate cancer: results of a phase II randomized discontinuation trial. Corn, PG; Elfiky, AA; Gordon, MS; Haas, NB; Harzstark, AL; Hussain, M; Lara, PN; Lin, CC; Logothetis, C; Scheffold, C; Schöffski, P; Sella, A; Small, EJ; Smith, DC; Smith, MR; Spira, AI; Srinivas, S; Sweeney, C; Vaishampayan, UN; Vogelzang, NJ; Weitzman, AL, 2013)	3.28
"Cabozantinib is an emerging novel agent with promising activity in advanced kidney cancer."	( Cabozantinib as a novel therapy for renal cell carcinoma. Vaishampayan, U, 2013)	2.55

Excerpt	Reference	Relevance
"Cabozantinib has a unique immunomodulatory profile and has demonstrated clinical efficacy as a monotherapy in mRCC and mUC, making it a potentially suitable partner for checkpoint inhibitor therapy."	( Cabozantinib in Combination with Immunotherapy for Advanced Renal Cell Carcinoma and Urothelial Carcinoma: Rationale and Clinical Evidence. Bergerot, P; Lamb, P; Pal, SK; Wang, E, 2019)	2.68
"Cabozantinib 60 mg/day has a favorable benefit/risk profile for Japanese patients with advanced HCC who have previously received one or two lines of systemic anticancer therapy including sorafenib. "	( Cabozantinib in Japanese patients with advanced hepatocellular carcinoma: a phase 2 multicenter study. Achira, M; Aikata, H; Furuse, J; Hagihara, A; Ikeda, M; Inaba, Y; Kato, N; Kimura, A; Kondo, S; Kudo, M; Kuroda, S; Morimoto, M; Motomura, K; Numata, K; Tsuchiya, K, 2021)	3.51
"Cabozantinib has an acceptable safety profile and is active in MTC. "	( Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer. Ball, DW; Cohen, EE; Cohen, RB; Forastiere, AA; Frye, J; Gagel, RF; Hong, DS; Janisch, L; Kurzrock, R; Mehra, R; Müller, T; Nauling, F; Ng, CS; Pfister, DG; Ratain, MJ; Salgia, R; Sherman, SI; Ye, L, 2011)	2.14
"Cabozantinib has been approved by U."	( Characterization of the metabolite of cabozantinib generated from liver microsomes and hepatocytes by ultra-high performance liquid chromatography coupled to quadrupole/orbitrap high resolution mass spectrometry. Chang, J; Chen, H; Chen, J; Chen, W; Liu, L; Liu, Q; Sun, X; Wang, X; Wu, X; Xu, Z; Zhang, J, 2021)	1.61
"Cabozantinib has been already tested in patients with liver cancer and was shown to be effective and safe in nontransplant patients."	( Phase II clinical trial of cabozantinib for the treatment of recurrent hepatocellular carcinoma after liver transplantation. Azhie, A; Bhat, M; Grant, RC; Herman, M; Knox, JJ; Wang, L, 2022)	1.74
"Cabozantinib has shown clinical activity in combination with checkpoint inhibitors in solid tumours. "	( Cabozantinib plus atezolizumab versus sorafenib for advanced hepatocellular carcinoma (COSMIC-312): a multicentre, open-label, randomised, phase 3 trial. Banerjee, K; Benzaghou, F; Borbath, I; Breder, V; Chan, SL; Cheng, AL; Fawcett, J; Gane, E; Hazra, S; Kaseb, A; Kelley, RK; Makharadze, T; Melkadze, T; Merle, P; Qin, S; Rangel, JDG; Rimassa, L; Ryoo, BY; Sukeepaisarnjaroen, W; Verset, G; Yau, T; Zhu, AX, 2022)	3.61
"Cabozantinib has shown promising activity for the treatment of various sarcomas, supporting further evaluation in this setting."	( Cabozantinib as an emerging treatment for sarcoma. Blay, JY; Ray-Coquard, I; Schöffski, P, 2020)	3.44
"Cabozantinib has shown anti-cancer effects in preclinical and clinical models of cancers derived from both epithelial and mesenchymal origins [prostate cancer, non small lung cancer, medullary thyroid cancer (MTC) and differentiated thyroid cancer (DTC), renal cell carcinoma, etc.]."	( Cabozantinib in Thyroid Cancer. Antonelli, A; Benvenga, S; Di Bari, F; Fallahi, P; Ferrari, SM; Materazzi, G; Miccoli, P, 2015)	2.58
"Cabozantinib has been authorised in the European Union for use in this setting."	( cabozantinib (COMETRIQ⁰). In medullary thyroid cancer: more harmful than beneficial, as is vandetanib. , 2016)	2.6
"Cabozantinib has been approved by the Food and Drug Administration to treat advanced medullary thyroid cancer and renal cell carcinoma."	( Modulating the function of ATP-binding cassette subfamily G member 2 (ABCG2) with inhibitor cabozantinib. Barbuti, AM; Chen, ZS; Wang, YJ; Wen, AW; Wurpel, JND; Yu, XY; Zhang, GN; Zhang, YK; Zhu, XJ, 2017)	1.4

Excerpt	Reference	Relevance
"Cabozantinib may enhance the effects of PD1 inhibitors on immunosurveillance by modulating the innate and adaptive immune system, through the inhibition of VEGF-VEGFR and Gas6-AXL/TYRO3/MER (TAM) axes, while the PD1 inhibitors may boost the antiangiogenic and pro-apoptotic effects of cabozantinib by modulating angiogenesis and T-cell cytotoxicity."	( Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning. Anido, U; Bello, E; Castellano, D; Costa, L; Durán, I; Martín-Couce, L; Mas, JM; Puente, J, 2022)	1.72
"Cabozantinib can enhance the efficacy of abiraterone by blocking multiple compensatory survival mechanisms, including IGFIR activation, and supports the assessment of the combination in a clinical trial."	( Cabozantinib Inhibits Abiraterone's Upregulation of IGFIR Phosphorylation and Enhances Its Anti-Prostate Cancer Activity. Bowden, M; Christie, A; Huang, Y; Kantoff, PW; Lee, GS; Sweeney, CJ; Wang, X, 2015)	3.3
"Cabozantinib can inhibit LM infection in mice and has important values in developing new anti-intracellular infection drug."	( [Cabozantinib inhibits Listeria monocytogenes infection in mice]. Cao, H; He, X; Long, M; Luo, J; Xiao, Q; Zhang, W, 2016)	2.79

Excerpt	Reference	Relevance
"Cabozantinib treatment decreased the viability of all cell lines both when grown in monolayer cultures and as tumor spheroids."	( Cabozantinib Is Effective in Melanoma Brain Metastasis Cell Lines and Affects Key Signaling Pathways. Aasen, SN; Bjørnstad, OV; Hoang, T; Mannsåker, TA; Parajuli, H; Sundstrøm, T; Thorsen, FA, 2021)	2.79
"Cabozantinib is an oral treatment approved for use in some patients with advanced RCC, including those with clear cell disease."	( CaboPoint: a phase II study of cabozantinib as second-line treatment in patients with metastatic renal cell carcinoma. Albiges, L; Grünwald, V; Guemas, E; Perol, D; Schmidinger, M; Taguieva-Pioger, N, 2022)	1.73
"All cabozantinib-treated mRCC patients from January 2014 to February 2019 in our institution were included. "	( Weight and skeletal muscle loss with cabozantinib in metastatic renal cell carcinoma. Afonso, D; Albiges, L; Alves Costa Silva, C; Benchimol-Zouari, A; Bidault, F; Colomba, E; Derosa, L; Elmawieh, J; Escudier, B; Flippot, R; Guida, A; Le Teuff, G; Raynard, B, 2022)	1.55
"Cabozantinib treatment prolonged progression-free survival (PFS) and improved objective response rate (ORR) compared with sunitinib in patients with advanced renal cell carcinoma (RCC) of intermediate or poor risk by International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) criteria in the phase II CABOSUN trial (NCT01835158). "	( Cabozantinib Versus Sunitinib for Untreated Patients with Advanced Renal Cell Carcinoma of Intermediate or Poor Risk: Subgroup Analysis of the Alliance A031203 CABOSUN trial. Choueiri, TK; Dakhil, S; Feldman, DR; George, DJ; Hahn, O; Halabi, S; Hessel, C; Mangeshkar, M; Michaelson, MD; Morris, MJ; Picus, J; Scheffold, C; Small, EJ; Walsh, M, 2019)	3.4
"Cabozantinib treatment led to stable disease in c-Met/β-catenin and Akt/c-Met mouse HCC while possessing limited efficacy on Akt/Ras and c-Myc liver tumours. "	( Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma. Calvisi, DF; Che, L; Chen, X; Cigliano, A; Evert, M; Liang, B; Lu, X; Shang, R; Song, X; Utpatel, K; Wang, J; Wang, P; Xu, M; Zhou, Y, 2021)	3.51
"Cabozantinib treatment resulted in significantly longer PFS compared with sunitinib in patients with metastatic PRCC."	( A comparison of sunitinib with cabozantinib, crizotinib, and savolitinib for treatment of advanced papillary renal cell carcinoma: a randomised, open-label, phase 2 trial. Adeniran, A; Alva, A; Balzer-Haas, N; Bjarnason, GA; Cole, S; George, DJ; Heng, DYC; Humphrey, P; Lara, PN; Narayan, V; Pal, SK; Plets, M; Shuch, B; Stein, M; Tangen, C; Thompson, IM; Tretiakova, M; Vaishampayan, U; Wright, J; Zhang, T, 2021)	2.35
"Cabozantinib treatment prolongs the ∆∆QTcF interval by 10-15 ms. "	( Assessment of cabozantinib treatment on QT interval in a phase 3 study in medullary thyroid cancer: evaluation of indirect QT effects mediated through treatment-induced changes in serum electrolytes. Lacy, SA; Miles, DR; Milwee, S; Nguyen, LT; Wada, DR; Yaron, Y, 2017)	2.26
"Cabozantinib treatment appeared to have modest clinical activity with a 4.3% response rate in patients who had received prior antiangiogenic therapy for GBM."	( Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy. Chamberlain, M; Cloughesy, TF; de Groot, J; Desjardins, A; Drappatz, J; Holland, J; Mikkelsen, T; Ping, J; Prados, MD; Reardon, DA; Schiff, D; Weitzman, R; Wen, PY, 2018)	2.26
"Cabozantinib treatment did not demonstrate better pain palliation than mitoxantrone-prednisone in heavily pretreated patients with mCRPC and symptomatic bone metastases. "	( Cabozantinib Versus Mitoxantrone-prednisone in Symptomatic Metastatic Castration-resistant Prostate Cancer: A Randomized Phase 3 Trial with a Primary Pain Endpoint. Antonarakis, ES; Basch, EM; Bennett, AV; Chi, KN; Dayan, E; de Bono, JS; de Souza, P; Dreicer, R; Dueck, AC; George, S; Holland, J; Hutson, TE; Kalebasty, AR; Mangeshkar, M; Marx, G; O'Sullivan, JM; Scher, HI; Scholz, M; Schwarz, JK; Vaishampayan, U; Vogelzang, N; Weitzman, AL, 2019)	3.4
"Cabozantinib treatment commonly results in thyroid dysfunction varying from subclinical hypothyroidism to symptomatic thyrotoxicosis."	( Cabozantinib-induced thyroid dysfunction: a review of two ongoing trials for metastatic bladder cancer and sarcoma. Apolo, AB; Celi, FS; del Rivero, J; Kummar, S; Madan, RA; Reynolds, J; Shawker, T; Yavuz, S, 2014)	2.57
"Cabozantinib treatment was synergistic with 13-cis-retinoic acid and chemotherapy agents topotecan and temozolomide."	( Sensitivity of neuroblastoma to the novel kinase inhibitor cabozantinib is mediated by ERK inhibition. Scorsone, K; Woodfield, SE; Zage, PE; Zhang, L, 2015)	1.38
"Cabozantinib treatment is also effective in reducing tumor growth in vivo."	( Sensitivity of neuroblastoma to the novel kinase inhibitor cabozantinib is mediated by ERK inhibition. Scorsone, K; Woodfield, SE; Zage, PE; Zhang, L, 2015)	1.38
"Cabozantinib treatment also resulted in improved progression-free survival (HR 0·51 [95% CI 0·41-0·62]; p<0·0001) and objective response (17% [13-22] with cabozantinib vs 3% [2-6] with everolimus; p<0·0001) per independent radiology review among all randomised patients."	( Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial. Aftab, DT; Agarwal, N; Choueiri, TK; Donskov, F; Escudier, B; Hammers, HJ; Heng, DYC; Hessel, C; Hutson, TE; Lee, JL; Mainwaring, PN; McDermott, DF; Motzer, RJ; Pal, S; Peltola, K; Powles, T; Rini, BI; Roth, BJ; Scheffold, C; Schmidinger, M; Schwab, G; Sternberg, CN; Tannir, NM, 2016)	2.6
"Cabozantinib treatment has no effect on osteoblast viability or differentiation, but increases osteoprotegerin mRNA (p=0.015) and protein levels (p=0.004) and down-modulates Receptor Activator of Nuclear Factor k B Ligand (RANKL) at both mRNA (p<0.001) and protein levels (p=0.043)."	( Cabozantinib targets bone microenvironment modulating human osteoclast and osteoblast functions. Denaro, V; Fioramonti, M; Iuliani, M; Manca, P; Pantano, F; Papapietro, N; Ribelli, G; Russo, A; Santini, D; Spiezia, F; Tonini, G; Vincenzi, B, 2017)	2.62
"Treatment with cabozantinib inhibited MET and VEGFR2 phosphorylation in vitro and in tumor models in vivo and led to significant reductions in cell invasion in vitro."	( Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Bentzien, F; Cancilla, B; Chen, J; Chou, YC; Chu, F; Engst, S; Joly, AH; Laird, AD; Lee, L; Lesch, J; Orf, J; Qian, F; Shi, Y; Tan, J; Yakes, FM; Yamaguchi, K; You, A; Yu, P, 2011)	2.15
"Treatment with cabozantinib, an inhibitor of MET and VEGFR2 signaling, has demonstrated clinical benefit in early trials in men with metastatic prostate cancer. "	( Cabozantinib and prostate cancer: inhibiting seed and disrupting soil? Lee, RJ; Smith, MR, 2014)	2.2
"Treatment with cabozantinib increased overall survival, delayed disease progression, and improved the objective response compared with everolimus. "	( Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial. Aftab, DT; Agarwal, N; Choueiri, TK; Donskov, F; Escudier, B; Hammers, HJ; Heng, DYC; Hessel, C; Hutson, TE; Lee, JL; Mainwaring, PN; McDermott, DF; Motzer, RJ; Pal, S; Peltola, K; Powles, T; Rini, BI; Roth, BJ; Scheffold, C; Schmidinger, M; Schwab, G; Sternberg, CN; Tannir, NM, 2016)	2.23
"Treatment with cabozantinib achieved responses, including 1 complete response."	( RET Fusion Lung Carcinoma: Response to Therapy and Clinical Features in a Case Series of 14 Patients. Ali, S; Dudnik, E; Dvir, A; Elvin, J; Gordon, N; Gottfried, M; Gutman, LS; Ilouze, M; Katz, A; Katznelson, R; Lipson, D; Miller, V; Moore, A; Moskovitz, M; Nechushtan, H; Neiman, V; Paz, K; Peled, N; Sarfaty, M; Saute, M; Sorotsky, HG; Wolner, M, 2017)	0.79

Excerpt	Reference	Relevance
" While these drugs were thought initially to be less toxic than traditional chemotherapy, they can have rare but serious and fatal toxicities."	( Aerodigestive fistula formation as a rare side effect of antiangiogenic tyrosine kinase inhibitor therapy for thyroid cancer. Baik, C; Balachandran, D; Blevins, DP; Cabanillas, ME; Dadu, R; Gunn, B; Hu, M; Ross, W, 2014)	0.4
"Fistula formation is a known but rare side effect of antiangiogenic tyrosine kinase inhibitors."	( Aerodigestive fistula formation as a rare side effect of antiangiogenic tyrosine kinase inhibitor therapy for thyroid cancer. Baik, C; Balachandran, D; Blevins, DP; Cabanillas, ME; Dadu, R; Gunn, B; Hu, M; Ross, W, 2014)	0.4
" Cutaneous reactions, one of the most frequently observed adverse effects associated with tyrosine kinase inhibitors, can significantly affect patients' quality of life and drug adherence and represent a major therapeutic challenge to maximizing the efficacy of targeted cancer therapy."	( Cutaneous adverse effects associated with the tyrosine-kinase inhibitor cabozantinib. Apolo, AB; Cowen, EW; Dahut, WL; DiGiovanna, JJ; Keen, CM; Nanda, S; Parnes, HL; Zuo, RC, 2015)	0.65
"Of 41 consecutive patients who received cabozantinib, 30 (73%) developed 1 or more cutaneous toxic effects."	( Cutaneous adverse effects associated with the tyrosine-kinase inhibitor cabozantinib. Apolo, AB; Cowen, EW; Dahut, WL; DiGiovanna, JJ; Keen, CM; Nanda, S; Parnes, HL; Zuo, RC, 2015)	0.92
"Cabozantinib monotherapy is associated with 1 or more cutaneous adverse events in most patients."	( Cutaneous adverse effects associated with the tyrosine-kinase inhibitor cabozantinib. Apolo, AB; Cowen, EW; Dahut, WL; DiGiovanna, JJ; Keen, CM; Nanda, S; Parnes, HL; Zuo, RC, 2015)	2.09
"To systematically review relevant literature comparing the oncological outcomes and adverse events of different systemic therapies for patients with metastatic non-ccRCC."	( A Systematic Review and Meta-analysis Comparing the Effectiveness and Adverse Effects of Different Systemic Treatments for Non-clear Cell Renal Cell Carcinoma. Albiges, L; Bensalah, K; Bex, A; Canfield, SE; Dabestani, S; Fernández-Pello, S; Giles, RH; Hofmann, F; Hora, M; Kuczyk, MA; Lam, TB; Ljungberg, B; Marconi, L; Merseburger, AS; Powles, T; Staehler, M; Tahbaz, R; Volpe, A, 2017)	0.46
" Sunitinib was associated with more Grade 3-4 adverse events than everolimus, although this was not statistically significant."	( A Systematic Review and Meta-analysis Comparing the Effectiveness and Adverse Effects of Different Systemic Treatments for Non-clear Cell Renal Cell Carcinoma. Albiges, L; Bensalah, K; Bex, A; Canfield, SE; Dabestani, S; Fernández-Pello, S; Giles, RH; Hofmann, F; Hora, M; Kuczyk, MA; Lam, TB; Ljungberg, B; Marconi, L; Merseburger, AS; Powles, T; Staehler, M; Tahbaz, R; Volpe, A, 2017)	0.46
" It is also essential to carefully monitor patients using TKI regarding possible adverse effects, which should be properly managed when occurring."	( Medullary thyroid carcinoma - Adverse events during systemic treatment: risk-benefit ratio. Maciel, LMZ; Magalhães, PKR, )	0.13
" The most frequent adverse events (AEs) are diarrhea, fatigue, hypertension, hand-foot syndrome, weight loss, nausea, and stomatitis."	( Management of Adverse Events Associated with Cabozantinib Therapy in Renal Cell Carcinoma. Danesi, R; Schmidinger, M, 2018)	0.74
" However, management of the adverse event profile is crucial to achieve optimum adherence and outcomes with the use of cabozantinib."	( Management of Adverse Events Associated with Cabozantinib Therapy in Renal Cell Carcinoma. Danesi, R; Schmidinger, M, 2018)	0.95
" Doses were reduced to 40 mg or 20 mg in patients experiencing grade 3 or intolerable grade 2 adverse events (AEs)."	( Safety and Efficacy of Cabozantinib in Metastatic Renal-Cell Carcinoma: Real-World Data From an Italian Managed Access Program. Bregni, M; Buti, S; Calabrò, F; Cartenì, G; Caserta, C; Cortesi, E; De Giorgi, U; Del Bene, G; Facchini, G; Fedeli, SL; Fornarini, G; Galli, L; Iacovelli, R; Mancini, ML; Masini, C; Massari, F; Mecozzi, A; Milella, M; Multari, AG; Ortega, C; Prisciandaro, M; Procopio, G; Ratta, R; Ricotta, R; Sabbatini, R; Santini, D; Sorarù, M; Sternberg, CN; Tortora, G; Tucci, M; Vernieri, C; Verzoni, E; Zustovich, F, 2018)	0.79
" TKIs also act systemically causing various adverse events (AEs)."	( Pazopanib, Cabozantinib, and Vandetanib in the Treatment of Progressive Medullary Thyroid Cancer with a Special Focus on the Adverse Effects on Hypertension. Bauer, J; Grimm, D; Grosse, J; Infanger, M; Kopp, S; Krüger, M; Milling, RV; Wehland, M, 2018)	0.87
" It is not known whether cabozantinib-induced adverse events are predictive factors of survival as in case of drugs such as sunitinib or axitinib."	( The correlation between the incidence of adverse events and progression-free survival in patients treated with cabozantinib for metastatic renal cell carcinoma (mRCC). Demkow, T; Dumnicka, P; Kucharz, J; Kusnierz-Cabala, B; Wiechno, P, 2019)	1.03
" Any grade adverse events (AEs) accounted for 92%, Grade 3/4 AEs rated at 36% with no major neurological side effects."	( Cabozantinib in Renal Cell Carcinoma With Brain Metastases: Safety and Efficacy in a Real-World Population. Bregni, M; Buti, S; Cartenì, G; Cortesi, E; Facchini, G; Fornarini, G; Galli, L; Peverelli, G; Prisciandaro, M; Procopio, G; Raimondi, A; Ratta, R; Tucci, M; Verzoni, E, 2019)	1.96
" A random effects model with a frequentist approach was computed for progression-free survival (PFS) data and for the proportion of patients experiencing a maximum of grade 3 or 4 adverse events (AEs)."	( Efficacy and Safety of Approved First-Line Tyrosine Kinase Inhibitor Treatments in Metastatic Renal Cell Carcinoma: A Network Meta-Analysis. Dempke, WCM; Eilers, A; Fenchel, K; Manz, KM; Morgan, J; Wittling, K, 2020)	0.56
" While previously limited to cases of intraabdominal bowel dehiscence, this report now suggests that wound dehiscence must be considered a known side effect of TKIs throughout the gastrointestinal tract, including the gastropharynx."	( Gastropharyngeal Anastomotic Leak in Medullary Thyroid Carcinoma Following Initiation of a Tyrosine Kinase Inhibitor: A Case Report of an Unusual Side Effect of Cabozantinib. Ackerman, J; Kent, S; Walker, P, 2020)	0.75
" Proteinuria was defined and evaluated using the National Cancer Institute's Common Terminology Criteria for Adverse Events."	( Proteinuria is a late-onset adverse event in patients treated with cabozantinib. Bonadio, AG; Bottici, V; Cappagli, V; Comai, G; Egidi, MF; Elisei, R; Giannese, D; La Manna, G; Moriconi, D; Viola, D; Vischini, G, 2021)	0.86
"Proteinuria is a quite frequent adverse event during cabozantinib treatment."	( Proteinuria is a late-onset adverse event in patients treated with cabozantinib. Bonadio, AG; Bottici, V; Cappagli, V; Comai, G; Egidi, MF; Elisei, R; Giannese, D; La Manna, G; Moriconi, D; Viola, D; Vischini, G, 2021)	1.11
" The most common adverse events were diarrhoea (76%), palmar-plantar erythrodysesthesia syndrome (60%), fatigue (50%), hypertension (42%), weight loss (40%) and oral mucositis (30%), with 32 (64%) patients requiring dose reductions, 27 (54%) having treatment interruptions and no cabozantinib-related deaths observed."	( Activity and safety of the multi-target tyrosine kinase inhibitor cabozantinib in patients with metastatic gastrointestinal stromal tumour after treatment with imatinib and sunitinib: European Organisation for Research and Treatment of Cancer phase II tri Ali, N; Benson, C; Blay, JY; Cousin, S; Dileo, P; Gelderblom, H; Italiano, A; Kasper, B; Kopeckova, K; LeCesne, A; Litiere, S; Marreaud, S; Menge, F; Mir, O; Nzokirantevye, A; Papai, Z; Schöffski, P; Vanden Bempt, I; Wardelmann, E; Wozniak, A; Zaffaroni, F, 2020)	0.97
" During CELESTIAL, the most common adverse events (AEs) experienced by patients receiving cabozantinib included palmar-plantar erythrodysesthesia, fatigue, gastrointestinal-related events, and hypertension."	( Management of Adverse Events Associated with Cabozantinib Treatment in Patients with Advanced Hepatocellular Carcinoma. Damicis, L; Darling, JO; Mindo, M; Schwartz, G, 2020)	1.04
" Only one patient had a grade ≥3 adverse event."	( Combination antiangiogenic tyrosine kinase inhibition and anti-PD1 immunotherapy in metastatic renal cell carcinoma: A retrospective analysis of safety, tolerance, and clinical outcomes. Armstrong, AJ; Brown, LC; Campbell, MT; Corn, P; Economides, M; Gao, J; Garmezy, B; George, DJ; Gupta, RT; Harrison, MR; Jonasch, E; Kao, C; Kinsey, EN; Laccetti, AL; Msaouel, P; Shah, A; Tannir, N; Venkatesan, A; Xiao, L; Zhang, T; Zurita-Saavedra, A, 2021)	0.62
" No grades 3 or 4 treatment-related adverse events (TRAEs) occurred within the first two cycles."	( Cabozantinib Plus Durvalumab in Patients With Advanced Urothelial Carcinoma After Platinum Chemotherapy: Safety and Preliminary Activity of the Open-Label, Single-Arm, Phase 2 ARCADIA Trial. Alessi, A; Briganti, A; Calareso, G; Colecchia, M; Madison, R; Marandino, L; Martini, A; Montorsi, F; Necchi, A; Raggi, D; Ross, JS, 2021)	2.06
"The durvalumab and cabozantinib combination was safe and endowed with preliminary clinical activity in patients with advanced UC."	( Cabozantinib Plus Durvalumab in Patients With Advanced Urothelial Carcinoma After Platinum Chemotherapy: Safety and Preliminary Activity of the Open-Label, Single-Arm, Phase 2 ARCADIA Trial. Alessi, A; Briganti, A; Calareso, G; Colecchia, M; Madison, R; Marandino, L; Martini, A; Montorsi, F; Necchi, A; Raggi, D; Ross, JS, 2021)	2.39
" Hazard ratios (HRs) including progression-free survival (PFS), overall survival (OS), odds ratios of disease control rate (DCR), objective response rate (ORR), and adverse events were compared indirectly with network meta-analysis using random model in software STATA version 13."	( Comparative efficacy and safety for second-line treatment with ramucirumab, regorafenib, and cabozantinib in patients with advanced hepatocellular carcinoma progressed on sorafenib treatment: A network meta-analysis. Chen, J; Wang, J; Xie, F, 2021)	0.84
" Adverse events were consistent with those in the overall population."	( Efficacy and safety of cabozantinib for patients with advanced hepatocellular carcinoma based on albumin-bilirubin grade. Abou-Alfa, GK; Chen, Y; Cheng, AL; Cicin, I; El-Khoueiry, AB; Hazra, S; Kelley, RK; Kim, S; Klümpen, HJ; Lin, ZZ; Meyer, T; Miksad, R; Sen, S; Youkstetter, J, 2022)	1.03
"To assess the clinical activity and toxic effects of cabozantinib to treat brain metastases in patients with metastatic RCC."	( Clinical Activity and Safety of Cabozantinib for Brain Metastases in Patients With Renal Cell Carcinoma. Abuqayas, B; Agarwal, N; Albigès, L; Barthélémy, P; Beuselinck, B; Bilen, MA; Bowman, IA; Brastianos, PK; Braun, DA; Choueiri, TK; Collier, KA; de Velasco, G; Dzimitrowicz, H; Farah, S; Flippot, R; Harrison, MR; Harshman, LC; Hirsch, L; Krajewski, KM; Lam, ET; Martinez Chanza, N; McKay, RR; Mortazavi, A; Rathi, N; Seront, E; Thouvenin, J; Varkaris, A; Xie, W; Xu, W; Zakharia, Y, 2021)	1.15
"1, and toxic effects of cabozantinib."	( Clinical Activity and Safety of Cabozantinib for Brain Metastases in Patients With Renal Cell Carcinoma. Abuqayas, B; Agarwal, N; Albigès, L; Barthélémy, P; Beuselinck, B; Bilen, MA; Bowman, IA; Brastianos, PK; Braun, DA; Choueiri, TK; Collier, KA; de Velasco, G; Dzimitrowicz, H; Farah, S; Flippot, R; Harrison, MR; Harshman, LC; Hirsch, L; Krajewski, KM; Lam, ET; Martinez Chanza, N; McKay, RR; Mortazavi, A; Rathi, N; Seront, E; Thouvenin, J; Varkaris, A; Xie, W; Xu, W; Zakharia, Y, 2021)	1.21
" Cabozantinib was well tolerated, with no unexpected toxic effects or neurological adverse events reported."	( Clinical Activity and Safety of Cabozantinib for Brain Metastases in Patients With Renal Cell Carcinoma. Abuqayas, B; Agarwal, N; Albigès, L; Barthélémy, P; Beuselinck, B; Bilen, MA; Bowman, IA; Brastianos, PK; Braun, DA; Choueiri, TK; Collier, KA; de Velasco, G; Dzimitrowicz, H; Farah, S; Flippot, R; Harrison, MR; Harshman, LC; Hirsch, L; Krajewski, KM; Lam, ET; Martinez Chanza, N; McKay, RR; Mortazavi, A; Rathi, N; Seront, E; Thouvenin, J; Varkaris, A; Xie, W; Xu, W; Zakharia, Y, 2021)	1.82
" Other grade ≥3 adverse events in >1 patient were hypertension (20%), diarrhoea (8%) and dehydration (8%)."	( Excessive toxicity of cabozantinib in a phase II study in patients with recurrent and/or metastatic salivary gland cancer. Dijkema, T; Jonker, MA; Krens, SD; Pegge, SAH; Uijen, MJM; van Boxtel, W; van Engen-van Grunsven, ACH; van Herpen, CML; Willems, SM, 2022)	1.04
"Full dose cabozantinib for metastatic renal cell carcinoma (mRCC) is 60 mg, but adverse events (AEs) may require dose reductions."	( Analysis of Toxicity and Clinical Outcomes in Full Versus Reduced Starting Dose Cabozantinib in Metastatic Renal Cell Carcinoma Patients. Bilen, MA; Brown, JT; Carthon, BC; Caulfield, S; Evans, ST; Goldman, JM; Harris, WB; Kucuk, O; Liu, Y; Martini, DJ; Master, VA; Nazha, B; Olsen, TA; Russler, GA; Shabto, JM; Uner, OE; Yantorni, L, 2022)	1.35
" While safety profiles are generally manageable with combination regimens, overlapping adverse events (AEs) and immune-related AEs can make treatment more complex."	( Management of adverse events associated with cabozantinib plus nivolumab in renal cell carcinoma: A review. Apolo, AB; Cordes, L; McGregor, B; Mortazavi, A; Salabao, C; Vandlik, S, 2022)	0.98
" This study aimed to assess the temporal trends in grade 3/4 adverse event (AE) rates and associated costs of nivolumab plus cabozantinib combination therapy versus sunitinib monotherapy in previously untreated patients with aRCC."	( Temporal Trends in Grade 3/4 Adverse Events and Associated Costs of Nivolumab Plus Cabozantinib Versus Sunitinib for Previously Untreated Advanced Renal Cell Carcinoma. Betts, KA; Bourlon, MT; Burotto, M; Choueiri, TK; Del Tejo, V; Du, EX; Geynisman, DM; Huo, S; McGregor, B; Porta, C; Suarez, C; Yang, X, 2022)	1.15
" Treatment-emergent adverse event (TEAE) rates were similar between arms."	( Efficacy and Safety of Telaglenastat Plus Cabozantinib vs Placebo Plus Cabozantinib in Patients With Advanced Renal Cell Carcinoma: The CANTATA Randomized Clinical Trial. Agarwal, N; Akella, L; Appleman, LJ; Davis, N; Escudier, B; Figlin, R; Gandhi, S; Geynisman, DM; Goodman, O; Iacovelli, R; Jain, RK; Lawrence, NJ; Lee, RJ; McGregor, B; Mellado, B; Motzer, R; Orford, K; Porta, C; Powles, T; Sepúlveda Sánchez, JM; Stadler, WM; Tannir, NM, 2022)	0.99
"Despite 4 approved combination regimens in the first-line setting for advanced renal cell carcinoma (aRCC), adverse event (AE) costs data are lacking."	( Grade 3/4 Adverse Event Costs of Immuno-oncology Combination Therapies for Previously Untreated Advanced Renal Cell Carcinoma. Betts, KA; Bourlon, MT; Burotto, M; Del Tejo, V; Du, EX; Geynisman, DM; Huo, S; McGregor, B; Porta, C; Sendhil, SR; Suarez, C; Yang, X, 2023)	0.91
"The primary outcomes of interest were the rate of grade ≥3 adverse events (AEs) occurring within 90 d of receipt of radiotherapy."	( Real-world Practice Patterns and Safety of Concurrent Radiotherapy and Cabozantinib in Metastatic Renal Cell Carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium. Beuselinck, B; Bouchard, G; Choueiri, TK; Hall, WA; Heng, DYC; Huang, J; Jackson-Spence, F; Kumar, SA; Labaki, C; Li, H; Loo Gan, C; McKay, RR; Meza, L; Pal, SK; Pan, E; Powles, T; Rose, BS; Sánchez-Ruiz, C; Schmidt, AL; Suarez, C; Weise, N; Xie, W, 2023)	1.14
" DOACs appear safe for VTE treatment for patients with RCC on cabozantinib, but optimized anticoagulation management, including individualized risk-benefit discussion, remains important in clinical practice."	( Cabozantinib Safety With Different Anticoagulants in Patients With Renal Cell Carcinoma. Barata, P; Bilen, MA; Choueiri, TK; Dizman, N; Gan, CL; Gao, X; Heng, D; Jani, C; Kaymakcalan, MD; Kilari, D; McGregor, B; McKay, RR; McManus, HD; Meza, L; Narra, R; Pal, S; Shayeb, AM; Sivakumar, A; Urman, D; Zhang, T, 2023)	2.59
" Adverse events were consistent with those in METEOR and the safety profile was acceptable."	( Final efficacy and safety results and biomarker analysis of a phase 2 study of cabozantinib in Japanese patients with advanced renal cell carcinoma. Kanayama, H; Kimura, A; Kuroda, S; Masumori, N; Miura, Y; Miyoshi, Y; Nakaigawa, N; Nishimura, K; Nozawa, M; Osawa, T; Oya, M; Sassa, N; Tamada, S; Tatsugami, K; Tomita, Y, 2023)	1.14
" Data on efficacy and safety are presented with the main focus on treatment-related hypertension, a well-known adverse effect (AE) of these TKIs."	( Cabozantinib, Vandetanib, Pralsetinib and Selpercatinib as Treatment for Progressed Medullary Thyroid Cancer with a Main Focus on Hypertension as Adverse Effect. Grimm, D; Højer Wang, L; Infanger, M; Kreissl, MC; Wehland, M; Wise, PM, 2023)	2.35
" In patients with PD-L1+ve and -ve ccRCC, niv, atezolizumab, ipi, and pembrolizumab were safe and effective alone and when combined with cabozantinib, tivozanib, axitinib, levantinib, and pegilodecakin."	( Efficacy and Safety of Checkpoint Inhibitors in Clear Cell Renal Cell Carcinoma: A Systematic Review of Clinical Trials. Aiman, W; Ali, MA; Butt, SK; Farrukh, M; Fatima, A; Garg, I; Habib, R; Kashif, T; Khan, H; Naveed, M; Niaz, R; Saeed, M; Zubair, H, 2023)	1.11
" The adoption of higher throughput and accessible animal models to evaluate TKI adverse effects will help in this regard."	( Cabozantinib-induced edema in zebrafish represents an adverse effect characterized by defects in lymphatic vasculature and renal function. C, MR; Chatti, K; Medishetti, R, 2023)	2.35
" However, cabozantinib dose modification and discontinuation due to symptomatic adverse events (AEs) remains a challenge."	( Electronic patient-reported outcome (e-PRO) monitoring for adverse event management during cabozantinib treatment in patients with advanced renal cell carcinoma: protocol for a three-arm, randomised, multicentre phase II trial (e-PRO vs paper-PRO or usual Fujii, Y; Iizumi, S; Kimura, G; Kitamura, H; Nagashima, Y; Osaka, T; Osawa, T; Shinohara, N; Tsubouchi, R, 2023)	1.53
" In terms of the safety profile, rate of adverse events, dose reduction and treatment interruption were assessed."	( Real-world efficacy and safety of cabozantinib following immune checkpoint inhibitor failure in Japanese patients with advanced renal cell carcinoma. Fukuda, H; Hashimoto, Y; Iizuka, J; Ishihara, H; Kobayashi, H; Kondo, T; Nemoto, Y; Tachibana, H; Takagi, T; Yoshida, K, 2023)	1.19
" All patients experienced at least one adverse event, and grade ≥ 3 adverse events were observed in 31 patients (55%)."	( Real-world efficacy and safety of cabozantinib following immune checkpoint inhibitor failure in Japanese patients with advanced renal cell carcinoma. Fukuda, H; Hashimoto, Y; Iizuka, J; Ishihara, H; Kobayashi, H; Kondo, T; Nemoto, Y; Tachibana, H; Takagi, T; Yoshida, K, 2023)	1.19
" All-grade adverse events occurred in 72% of patients, and grade 3 or higher adverse events occurred in 28% of patients."	( Efficacy and safety of second-line cabozantinib after immuno-oncology combination therapy for advanced renal cell carcinoma: Japanese multicenter retrospective study. Fujita, K; Hatakeyama, S; Hinata, N; Ichikawa, T; Kato, T; Kawasaki, Y; Kimura, T; Kitamura, H; Kojima, T; Kurahashi, T; Matsushita, Y; Miyake, H; Miyake, M; Numakura, K; Osawa, T; Sato, H; Sazuka, T; Takahashi, M; Tanaka, H; Ueda, K, 2023)	1.19

Excerpt	Reference	Relevance
" This method was successfully applied to a pharmacokinetic study of cabozantinib in rats."	( An LC-MS/MS method for the quantitation of cabozantinib in rat plasma: application to a pharmacokinetic study. Ji, X; Li, J; Li, L; Lu, W; Su, Q; Zhou, T, 2015)	0.92
" Pharmacokinetic (PK) drug-drug interactions (DDIs) were evaluated clinically between cabozantinib and (1) a CYP3A inducer (rifampin) in healthy volunteers, (2) a CYP3A inhibitor (ketoconazole) in healthy volunteers, and (3) a CYP2C8 substrate (rosiglitazone) in patients with solid tumors."	( Pharmacokinetic (PK) drug interaction studies of cabozantinib: Effect of CYP3A inducer rifampin and inhibitor ketoconazole on cabozantinib plasma PK and effect of cabozantinib on CYP2C8 probe substrate rosiglitazone plasma PK. Benrimoh, N; Engel, C; Holland, J; Lacy, S; Miles, D; Nguyen, L; O'Reilly, T, 2015)	0.89
" Following a high-fat meal (study 1), cabozantinib Cmax and AUC were increased (40."	( Evaluation of the effect of food and gastric pH on the single-dose pharmacokinetics of cabozantinib in healthy adult subjects. Armas, D; Grenier, J; Holland, J; Laberge, MK; Lacy, S; Mamelok, R; Nguyen, L; Swearingen, D, 2015)	0.91
" The analysis objective was to develop a population pharmacokinetic (PopPK) model in MTC patients and to use the model for exposure-response (ER) analysis of dose modifications."	( Population Pharmacokinetic Model of Cabozantinib in Patients with Medullary Thyroid Carcinoma and Its Application to an Exposure-Response Analysis. Jumbe, NL; Lacy, S; Miles, D; Nguyen, L, 2016)	0.71
"Cabozantinib at a dose of 40 mg daily with RT plus TMZ and post-RT TMZ for patients with newly diagnosed high-grade glioma was generally well tolerated, and demonstrated no pharmacokinetic interactions with concurrent TMZ."	( Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas. Chamberlain, MC; Cloughesy, T; Desjardins, A; Glantz, M; Mikkelsen, T; Reardon, DA; Schiff, D; Wen, PY, 2016)	2.11
" These models used cabozantinib exposure estimates from a previously published population pharmacokinetic model for cabozantinib in cancer patients that was updated with data from healthy-volunteer studies."	( Population pharmacokinetic/pharmacodynamic modeling of tumor growth kinetics in medullary thyroid cancer patients receiving cabozantinib. Jumbe, NL; Lacy, SA; Miles, DR; Nguyen, LT; Wada, DR, 2016)	0.97
" However, the GLSM for Cmax was 19% higher for the tablet formulation and the upper 90% CI for the ratio of GLSM (131."	( Pharmacokinetics of cabozantinib tablet and capsule formulations in healthy adults. Benrimoh, N; Lacy, S; Nguyen, L; Offman, E; Xie, Y, 2016)	0.76
"An integrated population pharmacokinetic (popPK) model was developed to describe the pharmacokinetics (PK) of tyrosine kinase inhibitor cabozantinib in healthy volunteers (HVs) and patients with various cancer types and to identify any differences in cabozantinib PK across these populations."	( A population pharmacokinetic model of cabozantinib in healthy volunteers and patients with various cancer types. Hutmacher, M; Lacy, S; Miles, D; Nguyen, L; Nielsen, J; Yang, B, 2018)	0.95
" Pharmacokinetic studies applied to transarterial chemoembolization are rare and pharmacodynamic studies even rarer."	( Clinical Pharmacokinetics and Pharmacodynamics of Transarterial Chemoembolization and Targeted Therapies in Hepatocellular Carcinoma. Bouattour, M; Hulin, A; Stocco, J, 2019)	0.51
"An integrated population pharmacokinetic (PPK) model was used to evaluate the effects of liver dysfunction on the pharmacokinetics (PK) of cabozantinib in patients with hepatocellular carcinoma and to determine whether clinical dosage adjustment may be necessary in this population."	( Updated Population Pharmacokinetic Model of Cabozantinib Integrating Various Cancer Types Including Hepatocellular Carcinoma. Chapel, S; Lacy, S; Nguyen, L; Tran, BD, 2019)	0.98

Excerpt	Reference	Relevance
" When cabozantinib was combined with a poxviral-based cancer vaccine targeting a self-antigen, the combination significantly reduced the function of regulatory T cells and increased cytokine production from effector T cells in response to the antigen."	( Dual effects of a targeted small-molecule inhibitor (cabozantinib) on immune-mediated killing of tumor cells and immune tumor microenvironment permissiveness when combined with a cancer vaccine. Aftab, DT; Ardiani, A; Donahue, RN; Hodge, JW; Kwilas, AR, 2014)	1.13
" The effect of the combination with the c-Met inhibitor cabozantinib was studied on cellular growth and invasion analyzed by the Chou-Talaly method."	( Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma. Andreiuolo, F; Cornilleau, G; Geoerger, B; Grill, J; Guerrini-Rousseau, L; Lacroix, L; Le Dret, L; Östman, A; Paulsson, J; Philippe, C; Puget, S; Richon, C; Truffaux, N; Vassal, G, 2015)	0.9
"Dasatinib exhibits antitumor effects in vitro that could be increased by the combination with another RTK inhibitor targeting c-Met."	( Preclinical evaluation of dasatinib alone and in combination with cabozantinib for the treatment of diffuse intrinsic pontine glioma. Andreiuolo, F; Cornilleau, G; Geoerger, B; Grill, J; Guerrini-Rousseau, L; Lacroix, L; Le Dret, L; Östman, A; Paulsson, J; Philippe, C; Puget, S; Richon, C; Truffaux, N; Vassal, G, 2015)	0.65
" Pharmacokinetic (PK) drug-drug interactions (DDIs) were evaluated clinically between cabozantinib and (1) a CYP3A inducer (rifampin) in healthy volunteers, (2) a CYP3A inhibitor (ketoconazole) in healthy volunteers, and (3) a CYP2C8 substrate (rosiglitazone) in patients with solid tumors."	( Pharmacokinetic (PK) drug interaction studies of cabozantinib: Effect of CYP3A inducer rifampin and inhibitor ketoconazole on cabozantinib plasma PK and effect of cabozantinib on CYP2C8 probe substrate rosiglitazone plasma PK. Benrimoh, N; Engel, C; Holland, J; Lacy, S; Miles, D; Nguyen, L; O'Reilly, T, 2015)	0.89
"A case of acute toxicity induced by erlotinib combined with cabozantinib is reported in this article."	( [Acute Myocardial Infarction and Purpuric Drug Eruption Caused by Erlotinib Combined with Cabozantinib:Report of One Case]. Hu, Y; Jia, LJ; Li, T; Zhang, J, 2019)	0.98
" Vascular endothelial growth factor receptor-tyrosine kinase inhibitors (VEGFR-TKIs) comprise a heterogeneous class of drugs with distinct pharmacological profiles, including potency, selectivity, pharmacokinetics and drug-drug interactions."	( Optimizing treatment of renal cell carcinoma with VEGFR-TKIs: a comparison of clinical pharmacology and drug-drug interactions of anti-angiogenic drugs. Crucitta, S; Danesi, R; Del Re, M; Fogli, S; Gianfilippo, G; Porta, C; Rini, BI; Schmidinger, M, 2020)	0.56
" Owing to its antitumor and immunomodulatory properties, cabozantinib is being developed in combination with immune checkpoint inhibitors."	( Cabozantinib in combination with atezolizumab versus sorafenib in treatment-naive advanced hepatocellular carcinoma: COSMIC-312 Phase III study design. Benzaghou, F; Cheng, AL; Hazra, S; Kelley, RK; Rimassa, L; W Oliver, J; Yau, T, 2020)	2.25
" A subgroup of immunotherapy-pretreated patients identified by baseline immune profile and potentially benefiting from combination with antiangiogenics requires further investigation."	( Translational randomized phase II trial of cabozantinib in combination with nivolumab in advanced, recurrent, or metastatic endometrial cancer. Backes, FJ; Block, MS; Brooks, DG; Colombo, I; Duska, L; Fleming, GF; Gadalla, R; Gaillard, SL; Girda, E; Jewell, A; Kehoe, S; Konstantinopoulos, PA; Lheureux, S; Li, X; Lien, S; Matei, DE; McCourt, C; McHale, M; Ohashi, PS; Pugh, T; Soleimani, S; Temkin, S; Wang, BX; Wang, L; Werner, TL; Wildman, R; Wright, J, 2022)	0.98
" We aimed to evaluate cabozantinib, a tyrosine kinase inhibitor with immunomodulatory properties, in combination with the PD-L1 inhibitor atezolizumab in metastatic castration-resistant prostate cancer."	( Cabozantinib in combination with atezolizumab in patients with metastatic castration-resistant prostate cancer: results from an expansion cohort of a multicentre, open-label, phase 1b trial (COSMIC-021). Agarwal, N; Choueiri, TK; Curran, D; Dorff, TB; Dreicer, R; Fang, B; Goel, S; Kelly, W; Loriot, Y; Maughan, BL; McGregor, B; McKay, RR; Pagliaro, L; Pal, S; Panneerselvam, A; Schwickart, M; Singh, P; Srinivas, S; Vaishampayan, U, 2022)	2.48
"Trabectedin alone or in combination with cabozantinib inhibited tumor growth in PDX UM mouse models."	( Preclinical Evaluation of Trabectedin in Combination With Targeted Inhibitors for Treatment of Metastatic Uveal Melanoma. Alsafadi, S; Decaudin, D; Etienne, V; Gelmi, MC; Glinkina, K; Jager, MJ; Jochemsen, AG; Kuipers, MJ; Nemati, F; Teunisse, AFAS, 2022)	0.99
" TKIs such as pazopanib and cabozantinib can interact with other drugs concomitantly administered, particularly with proton-pump inhibitors (PPIs), possibly impacting the effectiveness of the anticancer treatment and patients outcome."	( The impact of proton-pump inhibitors administered with tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma. Bersanelli, M; Brighi, N; Buti, S; Caffo, O; Cattrini, C; Cortellini, A; de Filippo, M; De Giorgi, U; Kinspergher, S; Malgeri, A; Mennitto, A; Puglisi, S; Rametta, A; Rebuzzi, SE; Roviello, G; Santoni, M; Scartabellati, G; Stellato, M; Tommasi, C; Verzoni, E, 2023)	1.2
" LOLA is the first prospective phase II trial aiming to assess the safety and activity of cabozantinib combined with lanreotide in WD NETs of gastroenteropancreatic (GEP), thoracic and of unknown origin."	( Assessing the safety and activity of cabozantinib combined with lanreotide in gastroenteropancreatic and thoracic neuroendocrine tumors: rationale and protocol of the phase II LOLA trial. Amoroso, V; Brizzi, MP; Campana, D; Cascella, T; Coppa, J; Corti, F; de Braud, F; Di Bartolomeo, M; Giuffrida, D; Leporati, R; Milione, M; Oldani, S; Panzuto, F; Porcu, L; Prinzi, N; Pulice, I; Pusceddu, S; Randon, G; Scotto, G; Spreafico, C; Stocchetti, BL, 2023)	1.4

Excerpt	Reference	Relevance
" The biological agent cabozantinib, an orally bioavailable tyrosine kinase inhibitor with activity against Met and vascular endothelial growth factor receptor 2, demonstrated promising results in a phase II trial and is currently being assessed in two large randomized phase 3 controlled trials."	( The changing landscape in metastatic castration-resistant prostate cancer. Joshua, AM; Leibowitz-Amit, R, 2013)	0.7
" The pharmacokinetics of four different dosages (iv 5, 10mg/kg and ig 15, 30mg/kg) revealed that XL184 was eliminated slowly, the t1/2 was longer than 10h and the absolute bioavailability was 25."	( Pharmacokinetics and tissue distribution model of cabozantinib in rat determined by UPLC-MS/MS. Chen, H; Hu, L; Lin, F; Ma, J; Wang, S; Wang, X; Wen, C; Zhang, Q, 2015)	0.67
"Our early structure-activity relationship study has identified benzo[b]carbazolone 6 as a high potency orally bioavailable ALK inhibitor."	( An orally available tyrosine kinase ALK and RET dual inhibitor bearing the tetracyclic benzo[b]carbazolone core. Ai, J; Gao, Y; Geng, M; Ji, Y; Song, Z; Xia, Z; Xing, L; Zhang, A, 2016)	0.43
"Cell membrane permeability is an important determinant for oral absorption and bioavailability of a drug molecule."	( Highly predictive and interpretable models for PAMPA permeability. Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR, 2017)	0.46
"A phase II randomised discontinuation trial assessed cabozantinib (XL184), an orally bioavailable inhibitor of tyrosine kinases including VEGF receptors, MET, and AXL, in a cohort of patients with metastatic melanoma."	( Phase II randomised discontinuation trial of the MET/VEGF receptor inhibitor cabozantinib in metastatic melanoma. Daud, A; Gordon, MS; Kluger, HM; Kurzrock, R; Moussa, AH; Samuel, TA; Schimmoller, F; Shapiro, GI; Weitzman, AL, 2017)	0.93
"Cabozantinib, an orally bioavailable inhibitor of tyrosine kinases including MET, AXL, and VEGF receptors, was assessed in patients with hepatocellular carcinoma (HCC) as part of a phase 2 randomized discontinuation trial with nine tumor-type cohorts."	( Cabozantinib in hepatocellular carcinoma: results of a phase 2 placebo-controlled randomized discontinuation study. Braiteh, F; Burris, H; Cohn, AL; Foster, P; Kelley, RK; Lee, Y; Spira, A; Su, WC; Van Cutsem, E; Verslype, C; Vogelzang, N; Yang, TS, 2017)	3.34
"Cabozantinib (XL184), an orally bioavailable inhibitor of vascular endothelial growth factor receptor 2 and MET, was assessed in a cohort of ovarian carcinoma patients as part of a phase 2 randomised discontinuation trial (RDT) with cohorts from nine different tumour types."	( A phase 2 randomised discontinuation trial of cabozantinib in patients with ovarian carcinoma. Berger, R; Buckanovich, RJ; Foster, PG; Kurzrock, R; Lee, Y; Sella, A; Smith, DC; Vergote, IB; Vogelzang, NJ; Weitzman, R; Wheler, J, 2017)	2.16
"To overcome challenges with traditional response assessment in anti-angiogenic agents, the current study uses T1 subtraction maps to quantify volumetric radiographic response in monotherapy with cabozantinib, an orally bioavailable tyrosine kinase inhibitor with activity against vascular endothelial growth factor receptor 2 (VEGFR2), hepatocyte growth factor receptor (MET), and AXL, in an open-label, phase II trial in patients with recurrent glioblastoma (GBM) (NCT00704288)."	( Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma. Aftab, DT; Chakhoyan, A; Chamberlain, M; Cloughesy, TF; de Groot, J; Desjardins, A; Drappatz, J; Ellingson, BM; Harris, RJ; Hessel, C; Holland, J; Leu, K; Mikkelsen, T; Ping, J; Prados, MD; Raymond, C; Reardon, DA; Schiff, D; Schwab, GM; Weitzman, R; Wen, PY; Woodworth, DC, 2018)	0.89
"Cabozantinib, an orally bioavailable tyrosine kinase inhibitor with activity against MET, vascular endothelial growth factor receptor 2, AXL, ROS1, and RET was assessed in patients with non-small-cell lung carcinoma (NSCLC) as part of a phase II randomized discontinuation trial with cohorts from 9 tumor types."	( Results of a Phase II Placebo-controlled Randomized Discontinuation Trial of Cabozantinib in Patients with Non-small-cell Lung Carcinoma. Aftab, DT; Gordon, MS; Hellerstedt, BA; Kluger, HM; Lara, P; Ramies, DA; Vogelzang, NJ; Yasenchak, CA, 2019)	2.19
" However, the poor solubility, rapid metabolism and low bioavailability of sorafenib greatly restricted its further clinical application."	( Evolution in medicinal chemistry of sorafenib derivatives for hepatocellular carcinoma. Chen, F; Chen, Z; Fang, Y; Huang, R; Le, J; Shao, J; Zhang, B; Zhao, R, 2019)	0.51
"The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs."	( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019)	0.51
" Extensive SAR and DMPK studies led to the identification of 20j, a potent and orally bioavailable MET kinase inhibitor with favorable kinase selectivity."	( Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate. Chen, T; Fang, WR; Huang, W; Li, YM; Liu, PF; Zhuo, LS, 2020)	0.56
" Overall, cationic Cabo-NPs offer a new prospect for safe and effective CNV treatment via enhancing the bioavailability of lipophilic cabozantinib."	( Development of mucoadhesive cationic polypeptide micelles for sustained cabozantinib release and inhibition of corneal neovascularization. Gao, Q; Grzybowski, A; Han, H; Ji, J; Shentu, X; Tang, X; Tang, Y; Yao, K; Yin, Q; Yu, X, 2020)	0.99
" Cabozantinib, an orally bioavailable multikinase inhibitor is now approved by Food and Drug Administration (FDA) for HCC patients."	( Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma. Calvisi, DF; Che, L; Chen, X; Cigliano, A; Evert, M; Liang, B; Lu, X; Shang, R; Song, X; Utpatel, K; Wang, J; Wang, P; Xu, M; Zhou, Y, 2021)	2.97
" Cabozantinib is a weak base that exhibits a pH-dependent solubility profile in vitro which raises concerns about its bioavailability in patients treated with proton pump inhibitors (PPIs)."	( The Effect of Concomitant Proton Pump Inhibitor and Cabozantinib on the Outcomes of Patients with Metastatic Renal Cell Carcinoma. Albiges, L; Alves Costa Silva, C; Auclin, E; Benchimoll-Zouari, A; Cerbone, L; Colomba, E; Combarel, D; Escudier, B; Flippot, R; Geraud, A; Guida, A; Mir, O; Paci, A; Rassy, E, 2021)	1.78
" Cabozantinib, a current therapeutic standard in metastatic renal cell carcinoma (mRCC), exhibits a pH-dependent solubility profile, which raises concerns about its bioavailability in patients treated with proton pump inhibitors (PPI)."	( The Effect of Concomitant Proton Pump Inhibitor and Cabozantinib on the Outcomes of Patients with Metastatic Renal Cell Carcinoma. Albiges, L; Alves Costa Silva, C; Auclin, E; Benchimoll-Zouari, A; Cerbone, L; Colomba, E; Combarel, D; Escudier, B; Flippot, R; Geraud, A; Guida, A; Mir, O; Paci, A; Rassy, E, 2021)	1.78
" Based on the architecture of our multi-targeted clinical candidate BPR1K871 (10), we designed and synthesized a series of quinazoline compounds as selective and orally bioavailable type II TRK inhibitors."	( Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization. Chang, L; Chen, CP; Chen, CT; Chen, PY; Chiu, CH; Fan, CM; Hsieh, HP; Huang, CL; Li, MC; Lin, WH; Su, YC; Wang, PC; Yeh, TK, 2021)	0.62
" We found that RCC cells are highly dependent on glutamine for proliferation, and this dependence strongly correlated with sensitivity to telaglenstat (CB-839), an investigational, first-in-class, selective, orally bioavailable GLS inhibitor."	( The glutaminase inhibitor telaglenastat enhances the antitumor activity of signal transduction inhibitors everolimus and cabozantinib in models of renal cell carcinoma. Chen, J; Dang, R; Emberley, E; Gross, M; Huang, T; Li, W; MacKinnon, A; Pan, A; Parlati, F; Singh, D; Sotirovska, N; Steggerda, SM; Wang, T, 2021)	0.83

Excerpt	Relevance	Reference
" Patients received daily oral dosing of 140 mg cabozantinib."	( A phase I study of cabozantinib (XL184) in patients with differentiated thyroid cancer. Brose, MS; Cabanillas, ME; Ferguson, KC; Holland, J; Sherman, SI, 2014)	0.99
" Emax models relating average concentration to average change in tumor size predicted that an average concentration of 79 and 58 ng/ml, respectively, would yield 50% of the maximum possible tumor reduction during the first 110 days of dosing and during the subsequent 110-280 days of dosing."	( Population pharmacokinetic/pharmacodynamic modeling of tumor growth kinetics in medullary thyroid cancer patients receiving cabozantinib. Jumbe, NL; Lacy, SA; Miles, DR; Nguyen, LT; Wada, DR, 2016)	0.64
" In mouse xenograft model, cabozantinib significantly inhibited MV4-11 and Molm-13 tumor growth at a dosage of 10 mg/kg and showed longer survival rate."	( Cabozantinib is selectively cytotoxic in acute myeloid leukemia cells with FLT3-internal tandem duplication (FLT3-ITD). Chen, CY; Hou, HA; Hu, CY; Liao, HA; Lin, LI; Lu, JW; Ou, DL; Tien, HF; Wang, AN, 2016)	2.17
" Cabozantinib tablets are investigational drug products considered to be potentially preferred pharmaceutical dosing forms."	( Pharmacokinetics of cabozantinib tablet and capsule formulations in healthy adults. Benrimoh, N; Lacy, S; Nguyen, L; Offman, E; Xie, Y, 2016)	1.67
" Patients were stratified by performance status and line of therapy, and randomly assigned using permuted blocks within strata to receive open-label oral daily dosing of erlotinib (150 mg), cabozantinib (60 mg), or erlotinib (150 mg) and cabozantinib (40 mg)."	( Erlotinib, cabozantinib, or erlotinib plus cabozantinib as second-line or third-line treatment of patients with EGFR wild-type advanced non-small-cell lung cancer (ECOG-ACRIN 1512): a randomised, controlled, open-label, multicentre, phase 2 trial. Aisner, SC; Bowden, M; Carbone, DP; Dahlberg, SE; Gerstner, GJ; Huang, Y; Khalid, AA; Lerner, RE; Neal, JW; Owonikoko, TK; Ramalingam, SS; Rubin, JL; Steen, PD; Stella, PJ; Wakelee, HA, 2016)	1.01
" The remaining patients were then dosed at 40 mg daily, the maximum tolerated dose (MTD)."	( Cabozantinib is well tolerated in acute myeloid leukemia and effectively inhibits the resistance-conferring FLT3/tyrosine kinase domain/F691 mutation. Amrein, PC; Avigan, DE; Ballen, KK; Behnan, T; Bergeron, MK; Blonquist, TM; Brunner, AM; Burke, M; Connolly, C; Fathi, AT; Fishman, KM; Foster, J; Hernandez, D; Hobbs, G; Joseph, C; Joyce, R; Levis, MJ; Logan, EK; McGregor, KL; McMasters, M; Moran, JA; Neuberg, DS; Perry, AM; Rae, J; Ramos, AY; Som, TT, 2018)	1.92
" Dosing and administration inputs were consistent with approved prescribing information and the clinical trials used to estimate efficacy and safety inputs."	( The Additional Costs per Month of Progression-Free Survival and Overall Survival: An Economic Model Comparing Everolimus with Cabozantinib, Nivolumab, and Axitinib for Second-Line Treatment of Metastatic Renal Cell Carcinoma. Duchesneau, E; Ghate, S; McDonald, E; Messali, A; Perez, JR; Swallow, E, 2018)	0.69
"This popPK analysis showed cabozantinib CL/F values to be higher for patients with MTC and may account for the higher dosage required in this patient population (140-mg) to achieve plasma exposures comparable to those in patients with RCC and other tumor types administered a 60-mg cabozantinib tablet dose."	( A population pharmacokinetic model of cabozantinib in healthy volunteers and patients with various cancer types. Hutmacher, M; Lacy, S; Miles, D; Nguyen, L; Nielsen, J; Yang, B, 2018)	1.05
" On the other hand, high dosage of the kinase inhibitors in pre-clinical models and hypoxia associated with angiogenesis may contribute to immune suppression in the tumor microenvironment."	( Immunomodulatory Effects of Current Targeted Therapies on Hepatocellular Carcinoma: Implication for the Future of Immunotherapy. Chen, CW; Cheng, AL; Hsu, C; Lin, YY; Ou, DL; Tan, CT, 2018)	0.48
"An integrated population pharmacokinetic (PPK) model was used to evaluate the effects of liver dysfunction on the pharmacokinetics (PK) of cabozantinib in patients with hepatocellular carcinoma and to determine whether clinical dosage adjustment may be necessary in this population."	( Updated Population Pharmacokinetic Model of Cabozantinib Integrating Various Cancer Types Including Hepatocellular Carcinoma. Chapel, S; Lacy, S; Nguyen, L; Tran, BD, 2019)	0.98
" We analyzed our institution's real-world experience with cabozantinib dosing in patients with mRCC to assess strategies to improve tolerability and patient outcomes."	( Cabozantinib use in metastatic renal cell carcinoma patients in clinical practice: Evaluation of dosing patterns, tolerability, and outcomes compared to clinical trials. Gourdin, TS; McElwee, JH; Mikoll, J; Sion, AM; Weeda, E, 2020)	2.25
" Dosing patterns were reviewed for each patient to allow calculation of median dose intensity and median duration of exposure."	( Cabozantinib use in metastatic renal cell carcinoma patients in clinical practice: Evaluation of dosing patterns, tolerability, and outcomes compared to clinical trials. Gourdin, TS; McElwee, JH; Mikoll, J; Sion, AM; Weeda, E, 2020)	2
" Several alternative dosing strategies were employed with 60% of patients requiring at least one dose intervention to manage toxicities."	( Cabozantinib use in metastatic renal cell carcinoma patients in clinical practice: Evaluation of dosing patterns, tolerability, and outcomes compared to clinical trials. Gourdin, TS; McElwee, JH; Mikoll, J; Sion, AM; Weeda, E, 2020)	2
" Further investigation is warranted to determine if alternative dosing strategies and lower median actual daily doses produce survival results comparable to published clinical trials."	( Cabozantinib use in metastatic renal cell carcinoma patients in clinical practice: Evaluation of dosing patterns, tolerability, and outcomes compared to clinical trials. Gourdin, TS; McElwee, JH; Mikoll, J; Sion, AM; Weeda, E, 2020)	2
" Therapeutic drug monitoring (TDM) could help to predict the risk for severe toxicities by quickly detecting overexposed patients followed by prospective adaptive dosing strategy."	( A simple and rapid liquid chromatography-mass spectrometry method to assay cabozantinib in plasma: Application to therapeutic drug monitoring in patients with renal cell carcinoma. Ciccolini, J; Deville, JL; Ferrer, F; Giocanti, M; Gravis, G; Lacarelle, B; Solas, C, 2020)	0.79
" The aim of the study was the comparative dose-response analysis of the drugs (0-100 µM) in well-differentiated (HepG2, Hep3B, and Huh7), moderately (SNU423), and poorly (SNU449) differentiated liver cancer cells in 2D/3D cultures."	( Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells. Cadenas, M; Chapresto-Garzón, R; Gómez-Bravo, MA; Muntané, J; Navarro-Villarán, E; Negrete, M; Padillo, FJ; Rodríguez-Hernández, MA; Victor, VM, 2020)	0.56
" However, real-world effectiveness and dosing patterns of cabozantinib are not well characterized."	( Cabozantinib real-world effectiveness in the first-through fourth-line settings for the treatment of metastatic renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium. Beuselinck, B; Bjarnason, GA; Choueiri, TK; de Velasco, G; Dizman, N; Donskov, F; Dudani, S; Gan, CL; Hansen, A; Heng, DYC; Lalani, AA; Lee, JL; Pal, SK; Rathi, N; Subasri, M; Szabados, B; Tran, B; Vaishampayan, UN; Wells, JC; Yan, F, 2021)	2.31
"A benefit:risk assessment for a less-frequent nivolumab 480 mg every 4 weeks + cabozantinib 40 mg every day dosing regimen was predicted using modeling and simulation of clinical trial data from nivolumab monotherapy studies and from the nivolumab 240 mg every 2 weeks + cabozantinib 40 mg every day dosing regimen, which demonstrated clinical benefit versus sunitinib in previously untreated advanced renal cell carcinoma (aRCC) in the phase III CheckMate 9ER trial (NCT03141177)."	( Exposure-Response Analysis to Support Nivolumab Once Every 4 Weeks Dosing in Combination with Cabozantinib in Renal Cell Carcinoma. Barcomb, H; Bello, A; Goldstein, S; Hamuro, L; Hu, Z; Passarell, J; Roy, A; Zhang, J; Zhu, L, 2022)	1.17
" To support cabozantinib dosing with the combination, this exposure-response analysis characterized the relationship of cabozantinib exposure with clinical endpoints."	( Cabozantinib exposure-response analysis for the phase 3 CheckMate 9ER trial of nivolumab plus cabozantinib versus sunitinib in first-line advanced renal cell carcinoma. Faggioni, R; Li, J; Ly, N; Roskos, L; Tran, BD, 2023)	2.73

Role	Description
tyrosine kinase inhibitor	Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
antineoplastic agent	A substance that inhibits or prevents the proliferation of neoplasms.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
quinolines	A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring.
organofluorine compound	An organofluorine compound is a compound containing at least one carbon-fluorine bond.
aromatic ether	Any ether in which the oxygen is attached to at least one aryl substituent.
dicarboxylic acid diamide
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (314)

Potency Measurements

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Fumarate hydratase	Homo sapiens (human)	Potency	37.2212	0.0030	8.7949	48.0869	AID1347053
PPM1D protein	Homo sapiens (human)	Potency	8.2891	0.0052	9.4661	32.9993	AID1347411
EWS/FLI fusion protein	Homo sapiens (human)	Potency	1.5952	0.0013	10.1577	42.8575	AID1259252; AID1259253; AID1259255; AID1259256
G	Vesicular stomatitis virus	Potency	2.6837	0.0123	8.9648	39.8107	AID1645842
polyprotein	Zika virus	Potency	37.2212	0.0030	8.7949	48.0869	AID1347053
tyrosine-protein kinase Yes	Homo sapiens (human)	Potency	1.0910	0.0000	5.0182	79.2586	AID686947
Interferon beta	Homo sapiens (human)	Potency	6.8877	0.0033	9.1582	39.8107	AID1347411; AID1645842
HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)	Potency	2.6837	0.0123	8.9648	39.8107	AID1645842
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	Potency	9.8498	0.0096	10.5250	35.4813	AID1479145; AID1479148
Inositol hexakisphosphate kinase 1	Homo sapiens (human)	Potency	2.6837	0.0123	8.9648	39.8107	AID1645842
cytochrome P450 2C9, partial	Homo sapiens (human)	Potency	2.6837	0.0123	8.9648	39.8107	AID1645842
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Epidermal growth factor receptor	Homo sapiens (human)	IC50 (µMol)	1.1180	0.0000	0.5369	10.0000	AID1352745; AID1466329; AID1594503
High affinity nerve growth factor receptor	Homo sapiens (human)	IC50 (µMol)	0.0723	0.0002	0.5436	10.0000	AID1829828
Acyl-CoA desaturase 1	Rattus norvegicus (Norway rat)	IC50 (µMol)	0.0013	0.0004	0.1594	1.7100	AID1421976
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	GI50	0.3166	0.0100	0.2669	0.9100	AID1271612; AID1271615; AID1271624; AID1271631; AID1271632; AID1433596; AID1433598; AID1433600; AID1704857; AID1704858
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	IC50 (µMol)	0.1699	0.0001	0.3484	3.5970	AID1180312; AID1204917; AID1271622; AID1271626; AID1271627; AID1271628; AID1271629; AID1271630; AID1276886; AID1283956; AID1283959; AID1312487; AID1312488; AID1312492; AID1318735; AID1352743; AID1466334; AID1484903; AID1500160; AID1548473; AID1548476; AID1708310; AID1735271; AID1735272; AID1735273; AID1895678; AID1895755; AID1895756; AID1895758; AID1895760; AID1905552
Insulin-like growth factor 1 receptor	Homo sapiens (human)	IC50 (µMol)	10.0000	0.0003	0.4308	8.0000	AID1352746
Hepatocyte growth factor receptor	Homo sapiens (human)	IC50 (µMol)	0.0791	0.0004	0.3722	10.0000	AID1157008; AID1180309; AID1190092; AID1276888; AID1276893; AID1304950; AID1304952; AID1318734; AID1352739; AID1368125; AID1421933; AID1421941; AID1421976; AID1466326; AID1466336; AID1500157; AID1544719; AID1647176; AID1690504; AID1698863; AID1704067; AID1708311; AID1743098; AID1743099; AID1780903; AID1802611; AID1849418
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	IC50 (µMol)	4.6763	0.0007	0.4708	10.0000	AID1180311; AID1276887; AID1276897; AID1318736; AID1352740; AID1466332; AID1500159; AID1708312; AID1895681
Fibroblast growth factor receptor 1	Homo sapiens (human)	IC50 (µMol)	0.0113	0.0002	0.9420	10.0000	AID1318738; AID1708314
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50 (µMol)	0.1780	0.0002	0.5335	10.0000	AID1352747
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	IC50 (µMol)	10.0000	0.0001	0.4912	10.0000	AID1466333
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	IC50 (µMol)	0.0120	0.0001	0.2914	7.0000	AID1318737; AID1708313
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	IC50 (µMol)	0.5617	0.0007	0.4116	9.1000	AID1276892; AID1276896; AID1318741; AID1352744; AID1484905; AID1500161; AID1708317; AID1849417; AID1895683
Kinesin-1 heavy chain	Homo sapiens (human)	GI50	0.0870	0.0870	0.0870	0.0870	AID1704858
Kinesin-1 heavy chain	Homo sapiens (human)	IC50 (µMol)	0.1900	0.0015	0.1963	0.4000	AID1283959
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	IC50 (µMol)	0.0060	0.0001	0.2264	4.9000	AID1510862
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	GI50	0.0030	0.0030	0.8305	4.6000	AID1271680
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	IC50 (µMol)	0.3151	0.0000	0.4830	8.8000	AID1157009; AID1180310; AID1276889; AID1276894; AID1283957; AID1283960; AID1304951; AID1304953; AID1318733; AID1352742; AID1368126; AID1421942; AID1421977; AID1466331; AID1466337; AID1487150; AID1500158; AID1510860; AID1708308; AID1743100; AID1802611; AID1849419; AID1895679; AID1895759
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	IC50 (µMol)	0.8877	0.0001	0.3275	9.5480	AID1276891; AID1276895; AID1318739; AID1466330; AID1500163; AID1557189; AID1708315; AID1894554; AID1895680
Angiopoietin-1 receptor	Homo sapiens (human)	IC50 (µMol)	0.0143	0.0004	0.5553	9.0700	AID1276890; AID1318740; AID1500162; AID1708316; AID1895684
Macrophage-stimulating protein receptor	Homo sapiens (human)	IC50 (µMol)	0.0690	0.0012	0.2698	3.3700	AID1352741
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	IC50 (µMol)	30.0000	0.0009	1.9014	10.0000	AID1780915
Coiled-coil domain-containing protein 6	Homo sapiens (human)	GI50	0.0290	0.0290	0.0290	0.0290	AID1704857
Coiled-coil domain-containing protein 6	Homo sapiens (human)	IC50 (µMol)	0.4615	0.0003	0.1429	0.8890	AID1312492; AID1895760
SAFB-like transcription modulator	Homo sapiens (human)	IC50 (µMol)	0.0013	0.0013	0.0013	0.0013	AID1895682
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Bone morphogenetic protein receptor type-1B	Homo sapiens (human)	Kd	30.0000	0.0009	1.1413	3.7000	AID1424922
Membrane-associated progesterone receptor component 1	Homo sapiens (human)	Kd	30.0000	0.2040	0.2040	0.2040	AID1425109
Cell division cycle 7-related protein kinase	Homo sapiens (human)	Kd	30.0000	0.5110	0.5110	0.5110	AID1424936
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Kd	30.0000	0.0008	1.5144	9.0000	AID1425121
ATP-dependent RNA helicase DDX3X	Homo sapiens (human)	Kd	30.0000	0.4350	0.4350	0.4350	AID1424975
Pyridoxal kinase	Homo sapiens (human)	Kd	30.0000	0.2860	5.0765	16.4040	AID1425106
Citron Rho-interacting kinase	Homo sapiens (human)	Kd	30.0000	0.0330	3.0646	48.8760	AID1424954
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Kd	30.0000	0.0028	1.4744	8.7000	AID1424953
Aurora kinase A	Homo sapiens (human)	Kd	16.6816	0.0001	0.7342	9.3000	AID1342794; AID1424917
Cyclin-G-associated kinase	Homo sapiens (human)	Kd	30.0000	0.0003	0.9086	28.6510	AID1425009
Ephrin type-B receptor 6	Homo sapiens (human)	Kd	30.0000	0.0000	1.0768	9.0000	AID1424995
Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)	Kd	30.0000	0.0260	1.3140	2.6020	AID1424896
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	0.7670	0.0020	1.6212	11.4330	AID1425155
Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)	Kd	30.0000	0.0940	1.3910	3.5070	AID1424926
Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.0170	0.3610	0.7050	AID1425097
Tyrosine-protein kinase JAK2	Homo sapiens (human)	Kd	30.0000	0.0000	0.8851	7.0000	AID1425031
Eukaryotic translation initiation factor 5B	Homo sapiens (human)	Kd	30.0000	0.2320	0.2320	0.2320	AID1424986
Rho-associated protein kinase 2	Homo sapiens (human)	Kd	30.0000	0.0002	2.7105	56.0660	AID1425158
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	Kd	30.0000	0.0008	1.8410	23.2730	AID1425208
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	Kd	30.0000	0.0057	2.0095	12.2010	AID1424997
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	Kd	30.0000	0.0170	1.9737	29.9570	AID1425162
U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)	Kd	30.0000	1.3820	1.3820	1.3820	AID1425174
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	Kd	30.0000	0.0120	1.6396	7.2000	AID1425161
Serine/threonine-protein kinase 16	Homo sapiens (human)	Kd	30.0000	0.0017	1.2483	9.9690	AID1425179
Serine/threonine-protein kinase 10	Homo sapiens (human)	Kd	30.0000	0.0000	2.9234	57.4530	AID1425177
Serine/threonine-protein kinase D3	Homo sapiens (human)	Kd	30.0000	0.0089	2.2738	23.3410	AID1425137
Structural maintenance of chromosomes protein 2	Homo sapiens (human)	Kd	30.0000	0.2090	0.6575	1.1060	AID1425173
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	Kd	30.0000	0.1700	1.5781	8.0000	AID1425050
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	Kd	30.0000	0.0082	2.3645	62.7720	AID1425054
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	Kd	30.0000	0.0140	1.8393	10.7330	AID1425033
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Kd	30.0000	0.0027	2.5694	30.3710	AID1425100
Tyrosine-protein kinase ABL1	Homo sapiens (human)	Kd	1.0980	0.0000	1.0411	13.4530	AID1424890
Epidermal growth factor receptor	Homo sapiens (human)	Kd	30.0000	0.0001	1.3514	20.8270	AID1424983
High affinity nerve growth factor receptor	Homo sapiens (human)	Kd	4.1080	0.0020	1.3484	9.2000	AID1425094
Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)	Kd	30.0000	0.1840	0.1840	0.1840	AID1425011
ADP/ATP translocase 2	Homo sapiens (human)	Kd	30.0000	0.4510	0.4510	0.4510	AID1425169
Protein kinase C beta type	Homo sapiens (human)	Kd	30.0000	0.0013	2.7081	26.3240	AID1425130
Insulin receptor	Homo sapiens (human)	Kd	30.0000	0.0017	1.0823	7.9060	AID1425026
Tyrosine-protein kinase Lck	Homo sapiens (human)	Kd	1.0450	0.0002	1.1174	24.2210	AID1425034
Tyrosine-protein kinase Fyn	Homo sapiens (human)	Kd	30.0000	0.0008	1.4238	8.4000	AID1425008
Cyclin-dependent kinase 1	Homo sapiens (human)	Kd	30.0000	0.2880	1.4952	3.0490	AID1424937
Glycogen phosphorylase, liver form	Homo sapiens (human)	Kd	30.0000	2.1210	2.1210	2.1210	AID1425146
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	Kd	30.0000	0.0048	1.0986	7.4000	AID1425003
Adenine phosphoribosyltransferase	Homo sapiens (human)	Kd	30.0000	0.0290	0.0290	0.0290	AID1424914
Tyrosine-protein kinase Yes	Homo sapiens (human)	Kd	30.0000	0.0003	1.3708	17.1520	AID1425212
Tyrosine-protein kinase Lyn	Homo sapiens (human)	Kd	1.3330	0.0006	1.0485	5.7000	AID1425037
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Kd	0.0860	0.0007	0.8642	27.5420	AID1425154
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Kd	30.0000	0.0010	1.9211	19.2170	AID1425022
Signal recognition particle receptor subunit alpha	Homo sapiens (human)	Kd	30.0000	0.0080	0.0080	0.0080	AID1425176
Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.2020	0.2020	0.2020	AID1424969
Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	30.0000	0.0002	1.6297	8.5000	AID1425076
Tyrosine-protein kinase HCK	Homo sapiens (human)	Kd	1.0980	0.0003	2.0343	15.9930	AID1425017
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Kd	30.0000	0.0001	1.0050	11.1070	AID1425104
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	Kd	30.0000	0.0470	9.6832	33.6550	AID1424915
Glycogen phosphorylase, brain form	Homo sapiens (human)	Kd	30.0000	3.5690	3.5690	3.5690	AID1425145
Breakpoint cluster region protein	Homo sapiens (human)	Kd	0.3420	0.0030	1.2196	17.3640	AID1424919
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	Kd	30.0000	0.0010	1.1393	19.3160	AID1425111
Fibroblast growth factor receptor 1	Homo sapiens (human)	Kd	30.0000	0.0003	1.5581	6.2000	AID1425004
Cyclin-dependent kinase 4	Homo sapiens (human)	Kd	30.0000	0.0033	1.6050	8.6000	AID1424946
ADP/ATP translocase 3	Homo sapiens (human)	Kd	30.0000	0.0060	0.2505	0.4950	AID1425170
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Kd	30.0000	0.0002	1.5077	9.6000	AID1425175
cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)	Kd	30.0000	0.0520	1.7535	3.4550	AID1425128
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Kd	30.0000	0.0002	1.6258	26.0180	AID1424924
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	Kd	30.0000	0.0001	2.0569	9.5000	AID1425110
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	Kd	30.0000	0.0040	6.7556	88.9030	AID1425093
Tyrosine-protein kinase Fer	Homo sapiens (human)	Kd	30.0000	0.0014	1.3604	8.8000	AID1425002
Protein kinase C alpha type	Homo sapiens (human)	Kd	30.0000	0.0003	1.7922	21.3520	AID1425129
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Kd	30.0000	0.0039	2.9479	23.2450	AID1425123
General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)	Kd	30.0000	0.0020	1.6906	12.0220	AID1424996
Casein kinase II subunit alpha'	Homo sapiens (human)	Kd	30.0000	0.0010	2.5309	28.8720	AID1424968
Ras-related protein Rab-6A	Homo sapiens (human)	Kd	30.0000	0.0330	0.0330	0.0330	AID1425150
Multifunctional protein ADE2	Homo sapiens (human)	Kd	30.0000	5.4810	5.4810	5.4810	AID1425098
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Kd	30.0000	0.0020	8.5577	49.2780	AID1425125
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Kd	30.0000	0.0130	0.7408	4.1000	AID1425124
Ferrochelatase, mitochondrial	Homo sapiens (human)	Kd	2.7140	0.2430	6.4343	67.9140	AID1425001; AID1801713
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	Kd	30.0000	0.0013	1.1805	4.8000	AID1425164
Tyrosine-protein kinase JAK1	Homo sapiens (human)	Kd	30.0000	0.0016	1.2166	7.8000	AID1425030
Cyclin-dependent kinase 2	Homo sapiens (human)	Kd	30.0000	0.0070	1.5179	10.4870	AID1424944
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	Kd	30.0000	0.1700	5.5791	22.4940	AID1424908
Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)	Kd	30.0000	4.1030	4.1030	4.1030	AID1424977
Mitogen-activated protein kinase 3	Homo sapiens (human)	Kd	30.0000	0.4300	5.2743	9.8000	AID1425061
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	Kd	30.0000	0.0030	3.9689	58.2400	AID1425069
Deoxycytidine kinase	Homo sapiens (human)	Kd	30.0000	0.0120	1.0875	2.1630	AID1424970
Mitogen-activated protein kinase 1	Homo sapiens (human)	Kd	30.0000	0.0001	2.7441	7.3000	AID1425056
Ephrin type-A receptor 2	Homo sapiens (human)	Kd	0.7460	0.0009	1.0752	8.1980	AID1424988
Ephrin type-B receptor 2	Homo sapiens (human)	Kd	30.0000	0.0004	3.1536	53.1980	AID1424992
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	Kd	30.0000	0.0009	1.5575	8.7000	AID1425207
UMP-CMP kinase	Homo sapiens (human)	Kd	30.0000	0.0030	0.0045	0.0060	AID1424959
Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)	Kd	30.0000	0.0030	0.0030	0.0030	AID1425107
Wee1-like protein kinase	Homo sapiens (human)	Kd	30.0000	0.0014	3.5389	65.1580	AID1425210
Heme oxygenase 2	Homo sapiens (human)	Kd	30.0000	0.1190	0.1190	0.1190	AID1425018
DnaJ homolog subfamily A member 1	Homo sapiens (human)	Kd	30.0000	0.9620	0.9620	0.9620	AID1424980
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	0.0006	1.0621	4.4000	AID1424910
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	0.0021	1.6196	8.7000	AID1424911
Dual specificity protein kinase TTK	Homo sapiens (human)	Kd	30.0000	0.0065	1.6269	8.5000	AID1425205
DNA replication licensing factor MCM4	Homo sapiens (human)	Kd	30.0000	0.6290	0.6290	0.6290	AID1425072
Myosin-10	Homo sapiens (human)	Kd	30.0000	0.2290	0.4935	0.7580	AID1425079
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Kd	30.0000	0.0039	1.6429	9.6000	AID1425039
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	Kd	0.0530	0.0002	0.9559	9.9000	AID1425006
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	Kd	30.0000	0.0600	1.5010	7.0000	AID1424921
Activin receptor type-1B	Homo sapiens (human)	Kd	30.0000	0.0040	1.5110	15.2580	AID1424901
TGF-beta receptor type-1	Homo sapiens (human)	Kd	30.0000	0.0050	2.2785	9.6000	AID1425196
TGF-beta receptor type-2	Homo sapiens (human)	Kd	30.0000	0.0800	1.8351	6.9000	AID1425197
Electron transfer flavoprotein subunit beta	Homo sapiens (human)	Kd	30.0000	0.0120	0.0120	0.0120	AID1424999
Tyrosine-protein kinase CSK	Homo sapiens (human)	Kd	30.0000	0.0010	3.4578	39.5530	AID1424960
Glycine--tRNA ligase	Homo sapiens (human)	Kd	30.0000	0.0400	0.0400	0.0400	AID1425010
Protein kinase C iota type	Homo sapiens (human)	Kd	30.0000	0.0260	9.3316	51.0180	AID1425133
Exosome RNA helicase MTR4	Homo sapiens (human)	Kd	30.0000	2.6070	2.6070	2.6070	AID1425168
Tyrosine-protein kinase Tec	Homo sapiens (human)	Kd	30.0000	0.0010	1.0095	8.7000	AID1425193
Tyrosine-protein kinase ABL2	Homo sapiens (human)	Kd	0.9180	0.0002	1.1249	14.9240	AID1424891
Tyrosine-protein kinase FRK	Homo sapiens (human)	Kd	0.5600	0.0003	1.2424	10.8370	AID1425007
Tyrosine-protein kinase SYK	Homo sapiens (human)	Kd	30.0000	0.0070	2.0052	9.2260	AID1425188
26S proteasome regulatory subunit 6B	Homo sapiens (human)	Kd	30.0000	0.0050	0.0050	0.0050	AID1425141
Mitogen-activated protein kinase 8	Homo sapiens (human)	Kd	30.0000	0.0110	2.0965	26.0590	AID1425063
Mitogen-activated protein kinase 9	Homo sapiens (human)	Kd	30.0000	0.0020	1.4596	8.1000	AID1425064
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	Kd	30.0000	0.0050	2.0462	6.6000	AID1425040
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)	Kd	30.0000	0.2080	3.6125	7.0170	AID1425113
Casein kinase I isoform alpha	Homo sapiens (human)	Kd	30.0000	0.0010	2.5756	19.3520	AID1424961
Casein kinase I isoform delta	Homo sapiens (human)	Kd	30.0000	0.0150	2.2270	18.3960	AID1424962
MAP kinase-activated protein kinase 2	Homo sapiens (human)	Kd	30.0000	0.0003	2.0274	14.7420	AID1425065
Elongation factor Tu, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.4640	0.4640	0.4640	AID1425206
Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	0.0120	0.3320	0.6520	AID1424932
Casein kinase I isoform epsilon	Homo sapiens (human)	Kd	30.0000	0.0130	1.4086	12.4090	AID1424963
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1.6890	1.6890	1.6890	AID1424894
Dual specificity protein kinase CLK1	Homo sapiens (human)	Kd	30.0000	0.0020	1.8791	29.8810	AID1424955
Dual specificity protein kinase CLK2	Homo sapiens (human)	Kd	30.0000	0.0070	1.1384	6.5000	AID1424956
Dual specificity protein kinase CLK3	Homo sapiens (human)	Kd	30.0000	0.0100	2.4499	9.0000	AID1424957
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Kd	30.0000	0.0060	2.4754	22.5430	AID1425013
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Kd	30.0000	0.0070	1.0057	6.1680	AID1425014
Cyclin-dependent kinase 7	Homo sapiens (human)	Kd	30.0000	0.0025	1.6783	7.7000	AID1424949
Cyclin-dependent kinase 9	Homo sapiens (human)	Kd	30.0000	0.0010	1.6166	9.9010	AID1424950
Ras-related protein Rab-27A	Homo sapiens (human)	Kd	30.0000	4.4930	4.4930	4.4930	AID1425149
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	Kd	30.0000	0.0061	1.5252	8.5000	AID1425027
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	Kd	30.0000	0.0170	2.8896	37.6050	AID1425160
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	Kd	30.0000	0.1100	1.5649	6.5000	AID1425086
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	Kd	30.0000	0.1700	5.9368	38.0880	AID1425087
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	Kd	30.0000	0.0034	2.3943	6.5000	AID1425043
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Kd	30.0000	0.0001	0.5711	5.0000	AID1425120
LIM domain kinase 1	Homo sapiens (human)	Kd	30.0000	0.0260	1.7840	21.0890	AID1425035
LIM domain kinase 2	Homo sapiens (human)	Kd	30.0000	0.0570	4.9717	52.0560	AID1425036
Mitogen-activated protein kinase 10	Homo sapiens (human)	Kd	30.0000	0.0010	1.6354	5.9000	AID1425057
Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	3.3160	3.3160	3.3160	AID1425211
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	Kd	30.0000	0.0060	1.4681	10.2120	AID1425126
Ephrin type-B receptor 3	Homo sapiens (human)	Kd	30.0000	0.0069	2.1713	6.4100	AID1424993
Ephrin type-A receptor 5	Homo sapiens (human)	Kd	30.0000	0.0002	1.2100	5.9000	AID1424990
Ephrin type-B receptor 4	Homo sapiens (human)	Kd	30.0000	0.0003	2.1678	26.3990	AID1424994
Ephrin type-A receptor 4	Homo sapiens (human)	Kd	30.0000	0.0012	3.1525	43.9420	AID1424989
Adenylate kinase 2, mitochondrial	Homo sapiens (human)	Kd	30.0000	1.0360	1.0360	1.0360	AID1424909
Adenosine kinase	Homo sapiens (human)	Kd	30.0000	0.0130	1.8368	3.4930	AID1424907
Ras-related protein Rab-10	Homo sapiens (human)	Kd	30.0000	1.3480	1.3480	1.3480	AID1425148
Actin-related protein 3	Homo sapiens (human)	Kd	30.0000	0.0360	2.7735	5.5110	AID1424899
Actin-related protein 2	Homo sapiens (human)	Kd	30.0000	0.0040	0.0040	0.0040	AID1424898
GTP-binding nuclear protein Ran	Homo sapiens (human)	Kd	30.0000	0.7590	0.7590	0.7590	AID1425153
Casein kinase I isoform gamma-2	Homo sapiens (human)	Kd	30.0000	0.0460	1.4506	6.6000	AID1424965
Cyclin-dependent kinase 3	Homo sapiens (human)	Kd	30.0000	0.0080	3.0602	63.6140	AID1424945
Cyclin-dependent kinase 6	Homo sapiens (human)	Kd	30.0000	0.0320	1.2007	3.3560	AID1424948
Cyclin-dependent-like kinase 5	Homo sapiens (human)	Kd	30.0000	0.0430	1.3757	8.3000	AID1424947
Cyclin-dependent kinase 16	Homo sapiens (human)	Kd	30.0000	0.0011	1.5855	10.0000	AID1424941
Cyclin-dependent kinase 17	Homo sapiens (human)	Kd	30.0000	0.0010	0.8233	5.6000	AID1424942
ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)	Kd	30.0000	0.9830	0.9830	0.9830	AID1425108
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Kd	30.0000	0.0002	1.1386	8.7730	AID1425038
DNA topoisomerase 2-beta	Homo sapiens (human)	Kd	30.0000	0.1480	1.2270	2.5970	AID1425203
Protein kinase C theta type	Homo sapiens (human)	Kd	30.0000	0.0007	1.6140	7.2000	AID1425134
Activin receptor type-1	Homo sapiens (human)	Kd	30.0000	0.0040	1.4853	16.1210	AID1424900
Macrophage-stimulating protein receptor	Homo sapiens (human)	Kd	30.0000	0.0030	2.0718	8.4000	AID1425078
Focal adhesion kinase 1	Homo sapiens (human)	Kd	30.0000	0.0005	1.2255	13.0390	AID1425142
Protein kinase C delta type	Homo sapiens (human)	Kd	30.0000	0.0002	1.1261	9.2060	AID1425131
Tyrosine-protein kinase BTK	Homo sapiens (human)	Kd	30.0000	0.0006	1.5299	10.1530	AID1424925
Activated CDC42 kinase 1	Homo sapiens (human)	Kd	30.0000	0.0020	1.7138	9.6000	AID1425201
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	Kd	0.2090	0.0002	1.6314	71.4840	AID1424972
Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)	Kd	30.0000	0.0031	1.4681	14.0430	AID1425052
Serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	30.0000	0.0002	1.7120	25.9020	AID1425185
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	Kd	30.0000	0.0037	1.8913	15.3890	AID1425122
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	Kd	2.3880	0.0002	2.6590	65.6770	AID1425042
Mitogen-activated protein kinase 7	Homo sapiens (human)	Kd	30.0000	0.0420	2.0073	9.9000	AID1425062
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	Kd	30.0000	0.0031	2.3045	6.0000	AID1425099
Serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	30.0000	0.0002	1.8602	17.5260	AID1425182
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	Kd	30.0000	0.0970	2.5995	12.4730	AID1425044
Integrin-linked protein kinase	Homo sapiens (human)	Kd	30.0000	0.0200	0.4603	1.3290	AID1425024
Rho-associated protein kinase 1	Homo sapiens (human)	Kd	30.0000	0.0003	1.7555	13.4620	AID1425157
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	Kd	30.0000	0.0018	1.0064	11.2690	AID1425200
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	Kd	30.0000	0.0005	1.0209	7.8000	AID1424929
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	Kd	30.0000	0.0003	1.5044	20.3010	AID1424928
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	Kd	30.0000	0.0001	2.1016	40.2910	AID1424981
Activin receptor type-2B	Homo sapiens (human)	Kd	30.0000	0.0076	2.7328	9.9000	AID1424902
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	Kd	30.0000	0.0190	2.5917	14.3770	AID1424923
Protein-tyrosine kinase 6	Homo sapiens (human)	Kd	1.7630	0.0043	1.7430	9.0000	AID1425144
cGMP-dependent protein kinase 1	Homo sapiens (human)	Kd	30.0000	0.0016	0.7072	3.8000	AID1425138
Cyclin-dependent kinase 13	Homo sapiens (human)	Kd	30.0000	0.0009	1.2571	4.5180	AID1424940
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	Kd	30.0000	0.0051	1.1093	8.3000	AID1425023
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	Kd	30.0000	0.0011	1.9450	30.4140	AID1425143
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	Kd	30.0000	0.0049	2.2835	29.9330	AID1425074
Structural maintenance of chromosomes protein 1A	Homo sapiens (human)	Kd	30.0000	0.3650	0.3650	0.3650	AID1425172
Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)	Kd	30.0000	0.0030	0.0030	0.0030	AID1424952
Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)	Kd	30.0000	0.0140	0.1425	0.2710	AID1424895
Ephrin type-A receptor 7	Homo sapiens (human)	Kd	30.0000	0.0025	1.4445	6.5000	AID1424991
Delta(24)-sterol reductase	Homo sapiens (human)	Kd	30.0000	0.4320	0.4320	0.4320	AID1424978
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	Kd	30.0000	0.0280	2.5286	22.7260	AID1425159
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Kd	30.0000	0.0030	1.2088	7.9000	AID1425081
Mitogen-activated protein kinase 11	Homo sapiens (human)	Kd	30.0000	0.0001	0.4610	3.7430	AID1425058
Serine/threonine-protein kinase STK11	Homo sapiens (human)	Kd	30.0000	0.0030	0.9949	5.9000	AID1425178
Serine/threonine-protein kinase N1	Homo sapiens (human)	Kd	30.0000	0.0013	3.1729	49.8130	AID1425117
Serine/threonine-protein kinase N2	Homo sapiens (human)	Kd	30.0000	0.0018	1.7527	9.9000	AID1425118
Mitogen-activated protein kinase 14	Homo sapiens (human)	Kd	30.0000	0.0000	0.5036	8.5000	AID1425059
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	Kd	30.0000	0.0300	1.9215	5.4600	AID1424930
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	Kd	30.0000	0.0110	1.5639	17.9840	AID1425045
Discoidin domain-containing receptor 2	Homo sapiens (human)	Kd	0.5010	0.0030	1.9888	42.2800	AID1424973
AP2-associated protein kinase 1	Homo sapiens (human)	Kd	30.0000	0.0012	1.3707	13.7110	AID1424889
Myosin light chain kinase 3	Homo sapiens (human)	Kd	30.0000	0.0020	1.6184	10.4240	AID1425082
Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)	Kd	30.0000	2.5660	2.5660	2.5660	AID1425019
Rab-like protein 3	Homo sapiens (human)	Kd	30.0000	4.8300	4.8300	4.8300	AID1425151
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	Kd	30.0000	0.0570	4.5547	14.0200	AID1424933
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	Kd	30.0000	0.0370	1.9625	9.5000	AID1424935
Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)	Kd	30.0000	0.0780	1.6997	3.9570	AID1424892
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	Kd	30.0000	0.0012	1.3350	9.9000	AID1425209
Uncharacterized protein FLJ45252	Homo sapiens (human)	Kd	30.0000	0.0030	1.2292	9.3110	AID1425147
Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)	Kd	30.0000	1.9160	3.0730	4.1470	AID1424893
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	Kd	30.0000	0.1160	0.7604	1.5000	AID1424998
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	Kd	30.0000	0.0001	1.8425	11.1030	AID1425068
ATP-dependent RNA helicase DHX30	Homo sapiens (human)	Kd	30.0000	0.0060	0.0060	0.0060	AID1424979
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	Kd	30.0000	0.0004	2.1612	18.7570	AID1425189
STE20-related kinase adapter protein alpha	Homo sapiens (human)	Kd	30.0000	0.3160	1.7208	3.6720	AID1425186
AarF domain-containing protein kinase 1	Homo sapiens (human)	Kd	30.0000	0.0230	3.1137	22.7470	AID1424904
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	Kd	30.0000	0.0051	1.6413	15.4350	AID1425053
MAP kinase-activated protein kinase 5	Homo sapiens (human)	Kd	30.0000	0.0080	1.1241	3.1180	AID1425067
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)	Kd	30.0000	0.0030	0.0030	0.0030	AID1425015
Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.0940	5.1673	65.3020	AID1424905
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)	Kd	2.9010	0.0030	2.7522	8.8000	AID1425115
Mitogen-activated protein kinase 15	Homo sapiens (human)	Kd	30.0000	0.0049	0.6880	4.5000	AID1425060
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	Kd	30.0000	0.0160	2.7428	19.6170	AID1425089
Serine/threonine-protein kinase Nek7	Homo sapiens (human)	Kd	30.0000	0.0030	3.6719	8.7000	AID1425088
ATP-dependent RNA helicase DDX1	Homo sapiens (human)	Kd	30.0000	0.0860	0.0860	0.0860	AID1424974
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	Kd	30.0000	0.0010	0.9378	5.5000	AID1425051
Aurora kinase B	Homo sapiens (human)	Kd	30.0000	0.0020	1.0614	22.8520	AID1424918
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	Kd	30.0000	0.0054	1.1029	4.9000	AID1425070
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	Kd	30.0000	0.1700	2.4294	8.3000	AID1425085
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	Kd	30.0000	0.0000	3.2331	52.8470	AID1424931
EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)	Kd	30.0000	0.3110	1.9519	3.8400	AID1425204
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)	Kd	30.0000	0.0440	0.9285	2.9000	AID1425116
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	Kd	30.0000	0.0700	6.5647	50.5360	AID1425049
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	Kd	30.0000	0.0060	1.5331	9.9000	AID1425047
Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)	Kd	30.0000	0.0580	1.9224	4.8360	AID1424984
Nucleolar GTP-binding protein 1	Homo sapiens (human)	Kd	30.0000	0.0090	4.1035	8.1980	AID1425016
Serine/threonine-protein kinase D2	Homo sapiens (human)	Kd	30.0000	0.0081	2.3723	25.0190	AID1425136
NUAK family SNF1-like kinase 2	Homo sapiens (human)	Kd	30.0000	0.0001	0.6774	4.6000	AID1425095
RNA cytidine acetyltransferase	Homo sapiens (human)	Kd	30.0000	1.2400	1.2400	1.2400	AID1425083
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	Kd	30.0000	0.0011	1.8165	41.7950	AID1425166
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	0.0000	3.8573	99.2320	AID1425171
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	Kd	30.0000	0.0002	2.7131	14.1960	AID1425191
dCTP pyrophosphatase 1	Homo sapiens (human)	Kd	30.0000	0.5730	1.7403	3.0540	AID1424971
Dual specificity protein kinase CLK4	Homo sapiens (human)	Kd	30.0000	0.0020	1.4122	8.3000	AID1424958
Casein kinase I isoform gamma-1	Homo sapiens (human)	Kd	30.0000	0.0530	2.0622	5.7000	AID1424964
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Kd	30.0000	0.0004	1.9194	9.7000	AID1425101
Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)	Kd	30.0000	0.0030	0.0045	0.0060	AID1425000
Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.0110	0.0110	0.0110	AID1425020
BMP-2-inducible protein kinase	Homo sapiens (human)	Kd	30.0000	0.0022	2.4097	56.0320	AID1424920
Obg-like ATPase 1	Homo sapiens (human)	Kd	30.0000	0.0030	0.0050	0.0070	AID1425096
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	Kd	30.0000	0.0017	3.4719	34.1450	AID1425029
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	Kd	30.0000	0.0023	1.7034	13.6380	AID1425213
Cyclin-dependent kinase 12	Homo sapiens (human)	Kd	30.0000	0.0320	1.8032	5.6350	AID1424939
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	Kd	30.0000	3.9200	3.9200	3.9200	AID1425084
Serine/threonine-protein kinase 26	Homo sapiens (human)	Kd	30.0000	0.0074	1.7380	8.3000	AID1425181
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)	Kd	30.0000	0.0070	0.0070	0.0070	AID1425187
Serine/threonine-protein kinase NLK	Homo sapiens (human)	Kd	30.0000	0.0060	1.0226	4.4000	AID1425090
5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)	Kd	30.0000	0.0050	1.1581	9.1280	AID1425127
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	Kd	30.0000	0.0009	1.7674	49.6010	AID1425192
Septin-9	Homo sapiens (human)	Kd	30.0000	0.0100	0.2430	0.6350	AID1425165
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	Kd	30.0000	0.0040	2.4153	23.7620	AID1425163
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	Kd	30.0000	0.0047	1.3935	10.0000	AID1425199
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	Kd	30.0000	0.0100	2.0176	12.9420	AID1425190
Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)	Kd	30.0000	0.0080	0.6353	1.6900	AID1424897
ALK tyrosine kinase receptor	Homo sapiens (human)	Kd	30.0000	0.0005	1.3507	7.7000	AID1424913
Serine/threonine-protein kinase ICK	Homo sapiens (human)	Kd	30.0000	0.0007	1.4717	9.3000	AID1425021
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	0.0025	1.7646	6.2000	AID1424912
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	Kd	30.0000	0.0005	1.5086	10.3180	AID1425167
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	Kd	30.0000	0.0024	1.3298	6.9000	AID1425046
Thyroid hormone receptor-associated protein 3	Homo sapiens (human)	Kd	30.0000	2.7460	2.7460	2.7460	AID1425198
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	Kd	30.0000	0.0280	1.8129	9.5000	AID1424982
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	Kd	30.0000	0.0005	1.9494	50.2140	AID1425055
Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	2.4590	0.0110	1.4797	6.7000	AID1425156
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	Kd	30.0000	0.0340	3.6252	50.0050	AID1424934
Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)	Kd	30.0000	0.0070	1.7137	25.5810	AID1425028
Serine/threonine-protein kinase 24	Homo sapiens (human)	Kd	30.0000	0.0065	0.8920	4.0840	AID1425180
Casein kinase I isoform gamma-3	Homo sapiens (human)	Kd	30.0000	0.0970	2.3978	8.7000	AID1424966
Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)	Kd	30.0000	0.0390	2.3970	8.4000	AID1425048
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Other Measurements

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Hepatocyte growth factor receptor	Homo sapiens (human)	INH	0.0210	0.0004	0.0084	0.0210	AID1235511
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	INH	0.0070	0.0008	0.0032	0.0070	AID1235512
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (2585)

Process	via Protein(s)	Taxonomy
positive regulation of gene expression	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
cartilage condensation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
ovarian cumulus expansion	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
osteoblast differentiation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
eye development	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
chondrocyte development	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
inflammatory response	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
central nervous system neuron differentiation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
proteoglycan biosynthetic process	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of bone mineralization	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
BMP signaling pathway	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
retinal ganglion cell axon guidance	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of chondrocyte differentiation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
ovulation cycle	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of osteoblast differentiation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
retina development in camera-type eye	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
endochondral bone morphogenesis	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of cartilage development	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
cellular response to BMP stimulus	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
negative regulation of chondrocyte proliferation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
dorsal/ventral pattern formation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
protein phosphorylation	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
cellular response to growth factor stimulus	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
heme biosynthetic process	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
positive regulation of lipoprotein transport	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cell division cycle 7-related protein kinase	Homo sapiens (human)
positive regulation of cell population proliferation	Cell division cycle 7-related protein kinase	Homo sapiens (human)
positive regulation of nuclear cell cycle DNA replication	Cell division cycle 7-related protein kinase	Homo sapiens (human)
positive regulation of G2/M transition of mitotic cell cycle	Cell division cycle 7-related protein kinase	Homo sapiens (human)
cell cycle phase transition	Cell division cycle 7-related protein kinase	Homo sapiens (human)
cell division	Cell division cycle 7-related protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	Cell division cycle 7-related protein kinase	Homo sapiens (human)
double-strand break repair via break-induced replication	Cell division cycle 7-related protein kinase	Homo sapiens (human)
signal transduction	Cell division cycle 7-related protein kinase	Homo sapiens (human)
positive regulation of centriole replication	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
centriole replication	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
positive regulation of centriole replication	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
cilium assembly	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
trophoblast giant cell differentiation	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
translational initiation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
chromosome segregation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptors	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
response to virus	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA secondary structure unwinding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of gene expression	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
Wnt signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of translation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of cell growth	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of cell growth	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of protein-containing complex assembly	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of protein autophosphorylation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of type I interferon production	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
DNA duplex unwinding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of interferon-alpha production	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of interferon-beta production	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
stress granule assembly	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of toll-like receptor 7 signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of toll-like receptor 8 signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
intracellular signal transduction	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of translation in response to endoplasmic reticulum stress	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytosolic ribosome assembly	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of apoptotic process	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of apoptotic process	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of viral genome replication	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
innate immune response	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of translation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of translational initiation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
lipid homeostasis	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cellular response to arsenic-containing substance	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cellular response to osmotic stress	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of chemokine (C-C motif) ligand 5 production	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
intrinsic apoptotic signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cellular response to virus	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of G1/S transition of mitotic cell cycle	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of non-canonical NF-kappaB signal transduction	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of non-canonical NF-kappaB signal transduction	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of protein acetylation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
positive regulation of protein K63-linked ubiquitination	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
protein localization to cytoplasmic stress granule	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
negative regulation of gene expression	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
gamete generation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cell differentiation	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
pyridoxal 5'-phosphate salvage	Pyridoxal kinase	Homo sapiens (human)
pyridoxal metabolic process	Pyridoxal kinase	Homo sapiens (human)
pyridoxamine metabolic process	Pyridoxal kinase	Homo sapiens (human)
mitotic cell cycle	Citron Rho-interacting kinase	Homo sapiens (human)
mitotic cytokinesis	Citron Rho-interacting kinase	Homo sapiens (human)
positive regulation of cytokinesis	Citron Rho-interacting kinase	Homo sapiens (human)
negative regulation of hippo signaling	Citron Rho-interacting kinase	Homo sapiens (human)
generation of neurons	Citron Rho-interacting kinase	Homo sapiens (human)
neuron apoptotic process	Citron Rho-interacting kinase	Homo sapiens (human)
DNA damage checkpoint signaling	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
inner cell mass cell proliferation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
DNA replication	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
DNA repair	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
chromatin remodeling	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
nucleus organization	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
regulation of double-strand break repair via homologous recombination	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
regulation of cell population proliferation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
signal transduction in response to DNA damage	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
mitotic G2/M transition checkpoint	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
positive regulation of cell cycle	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
negative regulation of gene expression, epigenetic	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
negative regulation of mitotic nuclear division	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
regulation of mitotic centrosome separation	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
negative regulation of G0 to G1 transition	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
cellular response to mechanical stimulus	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
cellular response to caffeine	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
replicative senescence	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
apoptotic process involved in development	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
negative regulation of DNA biosynthetic process	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein phosphorylation	Aurora kinase A	Homo sapiens (human)
response to wounding	Aurora kinase A	Homo sapiens (human)
liver regeneration	Aurora kinase A	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Aurora kinase A	Homo sapiens (human)
mitotic cell cycle	Aurora kinase A	Homo sapiens (human)
chromatin remodeling	Aurora kinase A	Homo sapiens (human)
protein phosphorylation	Aurora kinase A	Homo sapiens (human)
apoptotic process	Aurora kinase A	Homo sapiens (human)
spindle organization	Aurora kinase A	Homo sapiens (human)
spindle assembly involved in female meiosis I	Aurora kinase A	Homo sapiens (human)
mitotic centrosome separation	Aurora kinase A	Homo sapiens (human)
anterior/posterior axis specification	Aurora kinase A	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Aurora kinase A	Homo sapiens (human)
negative regulation of gene expression	Aurora kinase A	Homo sapiens (human)
peptidyl-serine phosphorylation	Aurora kinase A	Homo sapiens (human)
regulation of protein stability	Aurora kinase A	Homo sapiens (human)
negative regulation of protein binding	Aurora kinase A	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Aurora kinase A	Homo sapiens (human)
negative regulation of apoptotic process	Aurora kinase A	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	Aurora kinase A	Homo sapiens (human)
positive regulation of mitotic nuclear division	Aurora kinase A	Homo sapiens (human)
positive regulation of mitotic cell cycle	Aurora kinase A	Homo sapiens (human)
regulation of centrosome cycle	Aurora kinase A	Homo sapiens (human)
protein autophosphorylation	Aurora kinase A	Homo sapiens (human)
cell division	Aurora kinase A	Homo sapiens (human)
centrosome localization	Aurora kinase A	Homo sapiens (human)
cilium disassembly	Aurora kinase A	Homo sapiens (human)
protein localization to centrosome	Aurora kinase A	Homo sapiens (human)
positive regulation of mitochondrial fission	Aurora kinase A	Homo sapiens (human)
positive regulation of oocyte maturation	Aurora kinase A	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Aurora kinase A	Homo sapiens (human)
neuron projection extension	Aurora kinase A	Homo sapiens (human)
mitotic spindle organization	Aurora kinase A	Homo sapiens (human)
regulation of cytokinesis	Aurora kinase A	Homo sapiens (human)
receptor-mediated endocytosis	Cyclin-G-associated kinase	Homo sapiens (human)
endoplasmic reticulum organization	Cyclin-G-associated kinase	Homo sapiens (human)
Golgi organization	Cyclin-G-associated kinase	Homo sapiens (human)
negative regulation of neuron projection development	Cyclin-G-associated kinase	Homo sapiens (human)
synaptic vesicle uncoating	Cyclin-G-associated kinase	Homo sapiens (human)
protein localization to Golgi apparatus	Cyclin-G-associated kinase	Homo sapiens (human)
intracellular transport	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin coat assembly	Cyclin-G-associated kinase	Homo sapiens (human)
chaperone cofactor-dependent protein refolding	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin coat disassembly	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin-dependent endocytosis	Cyclin-G-associated kinase	Homo sapiens (human)
protein localization to plasma membrane	Cyclin-G-associated kinase	Homo sapiens (human)
Golgi to lysosome transport	Cyclin-G-associated kinase	Homo sapiens (human)
regulation of clathrin coat assembly	Cyclin-G-associated kinase	Homo sapiens (human)
protein phosphorylation	Ephrin type-B receptor 6	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-B receptor 6	Homo sapiens (human)
axon guidance	Ephrin type-B receptor 6	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA oxidase	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
lipid homeostasis	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
toll-like receptor 2 signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of cytokine-mediated signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
adaptive immune response	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of T-helper 1 type immune response	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
apoptotic process	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
inflammatory response	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
signal transduction	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
JNK cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cytokine-mediated signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein ubiquitination	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of chemokine production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interferon-alpha production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interferon-beta production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of type II interferon production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interleukin-1 beta production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interleukin-12 production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interleukin-2 production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of interleukin-6 production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
immature T cell proliferation in thymus	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of immature T cell proliferation in thymus	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
CD4-positive, alpha-beta T cell proliferation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
defense response to bacterium	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of apoptotic process	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
response to exogenous dsRNA	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
innate immune response	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of T-helper 1 cell differentiation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of JNK cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
defense response to Gram-positive bacterium	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
T cell receptor signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein homooligomerization	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
stress-activated MAPK cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of macrophage cytokine production	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
ERK1 and ERK2 cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
nucleotide-binding oligomerization domain containing 1 signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
nucleotide-binding oligomerization domain containing 2 signaling pathway	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
response to interleukin-1	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
response to interleukin-12	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
response to interleukin-18	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to lipoteichoic acid	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to peptidoglycan	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cellular response to muramyl dipeptide	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
activation of cysteine-type endopeptidase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
xenophagy	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of protein K63-linked ubiquitination	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of xenophagy	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of CD4-positive, alpha-beta T cell proliferation	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
chromatin remodeling	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
apoptotic process	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
chromosome segregation	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
regulation of sister chromatid cohesion	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
mitotic spindle assembly checkpoint signaling	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
cell division	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
regulation of chromosome segregation	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
meiotic sister chromatid cohesion, centromeric	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
mitochondrion organization	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial genome maintenance	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial fission	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
neural tube closure	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
apoptotic process	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrion organization	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
inner mitochondrial membrane organization	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
visual perception	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial fusion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
axonal transport of mitochondrion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
positive regulation of interleukin-17 production	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cristae formation	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
negative regulation of apoptotic process	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
GTP metabolic process	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
protein complex oligomerization	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
membrane fusion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
negative regulation of release of cytochrome c from mitochondria	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cellular senescence	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
membrane tubulation	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial inner membrane fusion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
positive regulation of T-helper 17 cell lineage commitment	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
positive regulation of platelet aggregation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of platelet activation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to antibiotic	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Tyrosine-protein kinase JAK2	Homo sapiens (human)
microglial cell activation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase JAK2	Homo sapiens (human)
chromatin remodeling	Tyrosine-protein kinase JAK2	Homo sapiens (human)
transcription by RNA polymerase II	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
immune response	Tyrosine-protein kinase JAK2	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase JAK2	Homo sapiens (human)
enzyme-linked receptor protein signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK2	Homo sapiens (human)
tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase JAK2	Homo sapiens (human)
mesoderm development	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of cell population proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of cardiac muscle cell apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cell-substrate adhesion	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to amine	Tyrosine-protein kinase JAK2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of cell-cell adhesion	Tyrosine-protein kinase JAK2	Homo sapiens (human)
actin filament polymerization	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
erythrocyte differentiation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cell migration	Tyrosine-protein kinase JAK2	Homo sapiens (human)
axon regeneration	Tyrosine-protein kinase JAK2	Homo sapiens (human)
intracellular mineralocorticoid receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of insulin secretion	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to lipopolysaccharide	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of type II interferon production	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of interleukin-1 beta production	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of interleukin-17 production	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of natural killer cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to hydroperoxide	Tyrosine-protein kinase JAK2	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
symbiont-induced defense-related programmed cell death	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to tumor necrosis factor	Tyrosine-protein kinase JAK2	Homo sapiens (human)
post-embryonic hemopoiesis	Tyrosine-protein kinase JAK2	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-12-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cellular response to interleukin-3	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-5-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
collagen-activated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-3-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
granulocyte-macrophage colony-stimulating factor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of T cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of protein import into nucleus	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase JAK2	Homo sapiens (human)
activation of Janus kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of DNA binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of MAPK cascade	Tyrosine-protein kinase JAK2	Homo sapiens (human)
negative regulation of neuron apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
post-translational protein modification	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of MHC class II biosynthetic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of nitric oxide biosynthetic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cell differentiation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of inflammatory response	Tyrosine-protein kinase JAK2	Homo sapiens (human)
modulation of chemical synaptic transmission	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of NK T cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase JAK2	Homo sapiens (human)
type II interferon-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
growth hormone receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of growth hormone receptor signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
mammary gland epithelium development	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-6-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of leukocyte proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
response to interleukin-12	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-35-mediated signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cellular response to lipopolysaccharide	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cellular response to dexamethasone stimulus	Tyrosine-protein kinase JAK2	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cellular response to virus	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of cold-induced thermogenesis	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of epithelial cell apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of postsynapse to nucleus signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of signaling receptor activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of T-helper 17 type immune response	Tyrosine-protein kinase JAK2	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of apoptotic process	Tyrosine-protein kinase JAK2	Homo sapiens (human)
regulation of translational initiation	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
ribosome assembly	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
translational initiation	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
epithelial to mesenchymal transition	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of protein phosphorylation	Rho-associated protein kinase 2	Homo sapiens (human)
response to ischemia	Rho-associated protein kinase 2	Homo sapiens (human)
aortic valve morphogenesis	Rho-associated protein kinase 2	Homo sapiens (human)
protein phosphorylation	Rho-associated protein kinase 2	Homo sapiens (human)
smooth muscle contraction	Rho-associated protein kinase 2	Homo sapiens (human)
canonical NF-kappaB signal transduction	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of endothelial cell migration	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of cardiac muscle hypertrophy	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of gene expression	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of gene expression	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of centrosome duplication	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of angiogenesis	Rho-associated protein kinase 2	Homo sapiens (human)
actin cytoskeleton organization	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of cell adhesion	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of cell migration	Rho-associated protein kinase 2	Homo sapiens (human)
cortical actin cytoskeleton organization	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of nervous system process	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of connective tissue growth factor production	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of actin cytoskeleton organization	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of myosin-light-chain-phosphatase activity	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of circadian rhythm	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of MAPK cascade	Rho-associated protein kinase 2	Homo sapiens (human)
modulation by host of viral process	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of nitric oxide biosynthetic process	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of keratinocyte differentiation	Rho-associated protein kinase 2	Homo sapiens (human)
rhythmic process	Rho-associated protein kinase 2	Homo sapiens (human)
centrosome duplication	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of stress fiber assembly	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of stress fiber assembly	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of focal adhesion assembly	Rho-associated protein kinase 2	Homo sapiens (human)
mRNA destabilization	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of biomineral tissue development	Rho-associated protein kinase 2	Homo sapiens (human)
cellular response to testosterone stimulus	Rho-associated protein kinase 2	Homo sapiens (human)
response to transforming growth factor beta	Rho-associated protein kinase 2	Homo sapiens (human)
protein localization to plasma membrane	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of fibroblast growth factor production	Rho-associated protein kinase 2	Homo sapiens (human)
blood vessel diameter maintenance	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of angiotensin-activated signaling pathway	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of protein localization to lysosome	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of cellular response to hypoxia	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of amyloid-beta formation	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of protein localization to early endosome	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of amyloid precursor protein catabolic process	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of establishment of endothelial barrier	Rho-associated protein kinase 2	Homo sapiens (human)
negative regulation of bicellular tight junction assembly	Rho-associated protein kinase 2	Homo sapiens (human)
cellular response to acetylcholine	Rho-associated protein kinase 2	Homo sapiens (human)
positive regulation of connective tissue replacement	Rho-associated protein kinase 2	Homo sapiens (human)
response to angiotensin	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of establishment of cell polarity	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of cell motility	Rho-associated protein kinase 2	Homo sapiens (human)
actomyosin structure organization	Rho-associated protein kinase 2	Homo sapiens (human)
peptidyl-threonine phosphorylation	Rho-associated protein kinase 2	Homo sapiens (human)
mitotic cytokinesis	Rho-associated protein kinase 2	Homo sapiens (human)
embryonic morphogenesis	Rho-associated protein kinase 2	Homo sapiens (human)
regulation of cell junction assembly	Rho-associated protein kinase 2	Homo sapiens (human)
Rho protein signal transduction	Rho-associated protein kinase 2	Homo sapiens (human)
autophagosome assembly	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein localization	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
negative regulation of cell population proliferation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
regulation of tumor necrosis factor-mediated signaling pathway	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
macroautophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
regulation of macroautophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
neuron projection regeneration	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
neuron projection development	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
cellular response to nutrient levels	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
response to starvation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
regulation of protein lipidation	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
positive regulation of autophagosome assembly	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
axon extension	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagy of mitochondrion	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
reticulophagy	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
piecemeal microautophagy of the nucleus	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
negative regulation of collateral sprouting	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
endothelial cell proliferation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
mRNA catabolic process	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
regulation of macroautophagy	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
positive regulation of RNA splicing	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cellular response to unfolded protein	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
response to endoplasmic reticulum stress	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
peptidyl-serine autophosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
IRE1-mediated unfolded protein response	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
positive regulation of JUN kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
mRNA splicing, via endonucleolytic cleavage and ligation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cellular response to hydrogen peroxide	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cellular response to glucose stimulus	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
positive regulation of endoplasmic reticulum unfolded protein response	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
insulin metabolic process	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
peptidyl-serine trans-autophosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
negative regulation of cytokine production	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
chromatin remodeling	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
regulation of DNA-templated transcription	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein phosphorylation	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
inflammatory response	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
axon guidance	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
positive regulation of CREB transcription factor activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
intracellular signal transduction	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
post-translational protein modification	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
negative regulation of DNA-templated transcription	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
regulation of postsynapse organization	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
cis assembly of pre-catalytic spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
mRNA splicing, via spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
osteoblast differentiation	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
negative regulation of cytokine production	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
chromatin remodeling	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
regulation of DNA-templated transcription	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
protein phosphorylation	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
inflammatory response	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
positive regulation of CREB transcription factor activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
intracellular signal transduction	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
post-translational protein modification	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 16	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 10	Homo sapiens (human)
lymphocyte aggregation	Serine/threonine-protein kinase 10	Homo sapiens (human)
regulation of lymphocyte migration	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein kinase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D3	Homo sapiens (human)
sphingolipid biosynthetic process	Serine/threonine-protein kinase D3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase D3	Homo sapiens (human)
phospholipase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D3	Homo sapiens (human)
mitotic chromosome condensation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
meiotic chromosome condensation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
meiotic chromosome segregation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
cell division	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
kinetochore organization	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
positive regulation of chromosome segregation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
positive regulation of chromosome separation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
positive regulation of chromosome condensation	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
cellular response to stress	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
microvillus assembly	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
negative regulation of cell-matrix adhesion	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of cell migration	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of ARF protein signal transduction	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of hippo signaling	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
negative regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of GTPase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
regulation of JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of keratinocyte migration	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of focal adhesion assembly	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
positive regulation of focal adhesion disassembly	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
regulation of MAPK cascade	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
neuron projection morphogenesis	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
sister chromatid segregation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
inner cell mass cell fate commitment	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
inner cell mass cellular morphogenesis	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
hormone-mediated signaling pathway	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of transforming growth factor beta receptor signaling pathway	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
keratinocyte differentiation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of actin filament polymerization	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of intracellular estrogen receptor signaling pathway	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
hippo signaling	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of protein-containing complex assembly	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
negative regulation of cyclin-dependent protein serine/threonine kinase activity	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
cytoplasmic sequestering of protein	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
cell division	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
mammary gland epithelial cell differentiation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
negative regulation of protein localization to nucleus	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of ubiquitin-dependent protein catabolic process	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
positive regulation of apoptotic process	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of organ growth	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
regulation of cell growth	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cytoskeleton organization	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
positive regulation of angiogenesis	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
dendritic spine development	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cellular response to organic cyclic compound	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cell-cell adhesion	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
response to oxidative stress	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of ubiquitin-protein transferase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of phospholipase C activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mitotic cell cycle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neural tube closure	Tyrosine-protein kinase ABL1	Homo sapiens (human)
B-1 B cell homeostasis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of protein phosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
B cell proliferation involved in immune response	Tyrosine-protein kinase ABL1	Homo sapiens (human)
transitional one stage B cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mismatch repair	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of DNA-templated transcription	Tyrosine-protein kinase ABL1	Homo sapiens (human)
autophagy	Tyrosine-protein kinase ABL1	Homo sapiens (human)
DNA damage response	Tyrosine-protein kinase ABL1	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
canonical NF-kappaB signal transduction	Tyrosine-protein kinase ABL1	Homo sapiens (human)
associative learning	Tyrosine-protein kinase ABL1	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage	Tyrosine-protein kinase ABL1	Homo sapiens (human)
response to xenobiotic stimulus	Tyrosine-protein kinase ABL1	Homo sapiens (human)
post-embryonic development	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of autophagy	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of endothelial cell migration	Tyrosine-protein kinase ABL1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cerebellum morphogenesis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of cell-cell adhesion	Tyrosine-protein kinase ABL1	Homo sapiens (human)
microspike assembly	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin cytoskeleton organization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin filament polymerization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of endocytosis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of cell adhesion	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuron differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
BMP signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of BMP signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of axon extension	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of microtubule polymerization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of Cdc42 protein signal transduction	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of type II interferon production	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of interleukin-2 production	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of actin cytoskeleton organization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of osteoblast proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to oxidative stress	Tyrosine-protein kinase ABL1	Homo sapiens (human)
response to endoplasmic reticulum stress	Tyrosine-protein kinase ABL1	Homo sapiens (human)
platelet-derived growth factor receptor-beta signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein modification process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuropilin signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
signal transduction in response to DNA damage	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of neuron apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
endothelial cell migration	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of T cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of vasoconstriction	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of mitotic cell cycle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of mitotic cell cycle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Tyrosine-protein kinase ABL1	Homo sapiens (human)
alpha-beta T cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of fibroblast proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
spleen development	Tyrosine-protein kinase ABL1	Homo sapiens (human)
thymus development	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
activated T cell proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuromuscular process controlling balance	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of release of sequestered calcium ion into cytosol	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of oxidoreductase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuron apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of ubiquitin-protein transferase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
myoblast proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of stress fiber assembly	Tyrosine-protein kinase ABL1	Homo sapiens (human)
establishment of localization in cell	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of cell cycle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mitochondrial depolarization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of focal adhesion assembly	Tyrosine-protein kinase ABL1	Homo sapiens (human)
Bergmann glial cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cardiac muscle cell proliferation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuroepithelial cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to hydrogen peroxide	Tyrosine-protein kinase ABL1	Homo sapiens (human)
ERK1 and ERK2 cascade	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase ABL1	Homo sapiens (human)
DNA conformation change	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to lipopolysaccharide	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Tyrosine-protein kinase ABL1	Homo sapiens (human)
response to epinephrine	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of protein serine/threonine kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular senescence	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cell-cell adhesion	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of dendrite development	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreading	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of long-term synaptic potentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of hematopoietic stem cell differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of extracellular matrix organization	Tyrosine-protein kinase ABL1	Homo sapiens (human)
podocyte apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cellular response to dopamine	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of establishment of T cell polarity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
DN4 thymocyte differentiation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein localization to cytoplasmic microtubule plus-end	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of microtubule binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of actin filament binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of modification of synaptic structure	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of blood vessel branching	Tyrosine-protein kinase ABL1	Homo sapiens (human)
activation of protein kinase C activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of double-strand break repair via homologous recombination	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of Wnt signaling pathway, planar cell polarity pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
regulation of cell motility	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Tyrosine-protein kinase ABL1	Homo sapiens (human)
positive regulation of T cell migration	Tyrosine-protein kinase ABL1	Homo sapiens (human)
negative regulation of cellular senescence	Tyrosine-protein kinase ABL1	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cell surface receptor signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Epidermal growth factor receptor	Homo sapiens (human)
MAPK cascade	Epidermal growth factor receptor	Homo sapiens (human)
ossification	Epidermal growth factor receptor	Homo sapiens (human)
embryonic placenta development	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
hair follicle development	Epidermal growth factor receptor	Homo sapiens (human)
translation	Epidermal growth factor receptor	Homo sapiens (human)
signal transduction	Epidermal growth factor receptor	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
activation of phospholipase C activity	Epidermal growth factor receptor	Homo sapiens (human)
salivary gland morphogenesis	Epidermal growth factor receptor	Homo sapiens (human)
midgut development	Epidermal growth factor receptor	Homo sapiens (human)
learning or memory	Epidermal growth factor receptor	Homo sapiens (human)
circadian rhythm	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Epidermal growth factor receptor	Homo sapiens (human)
diterpenoid metabolic process	Epidermal growth factor receptor	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
cerebral cortex cell migration	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cell growth	Epidermal growth factor receptor	Homo sapiens (human)
lung development	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cell migration	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of superoxide anion generation	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
response to cobalamin	Epidermal growth factor receptor	Homo sapiens (human)
response to hydroxyisoflavone	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to reactive oxygen species	Epidermal growth factor receptor	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
ERBB2-EGFR signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of epidermal growth factor receptor signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of protein catabolic process	Epidermal growth factor receptor	Homo sapiens (human)
vasodilation	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
ovulation cycle	Epidermal growth factor receptor	Homo sapiens (human)
hydrogen peroxide metabolic process	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of apoptotic process	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of MAP kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
tongue development	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of cyclin-dependent protein serine/threonine kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of DNA repair	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of DNA replication	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of bone resorption	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of DNA-templated transcription	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of vasoconstriction	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of mitotic cell cycle	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Epidermal growth factor receptor	Homo sapiens (human)
regulation of JNK cascade	Epidermal growth factor receptor	Homo sapiens (human)
symbiont entry into host cell	Epidermal growth factor receptor	Homo sapiens (human)
protein autophosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
astrocyte activation	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of fibroblast proliferation	Epidermal growth factor receptor	Homo sapiens (human)
digestive tract morphogenesis	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Epidermal growth factor receptor	Homo sapiens (human)
neuron projection morphogenesis	Epidermal growth factor receptor	Homo sapiens (human)
epithelial cell proliferation	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of epithelial cell proliferation	Epidermal growth factor receptor	Homo sapiens (human)
regulation of peptidyl-tyrosine phosphorylation	Epidermal growth factor receptor	Homo sapiens (human)
protein insertion into membrane	Epidermal growth factor receptor	Homo sapiens (human)
response to calcium ion	Epidermal growth factor receptor	Homo sapiens (human)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of synaptic transmission, glutamatergic	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of glial cell proliferation	Epidermal growth factor receptor	Homo sapiens (human)
morphogenesis of an epithelial fold	Epidermal growth factor receptor	Homo sapiens (human)
eyelid development in camera-type eye	Epidermal growth factor receptor	Homo sapiens (human)
response to UV-A	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of mucus secretion	Epidermal growth factor receptor	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to amino acid stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to mechanical stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to cadmium ion	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to epidermal growth factor stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to estradiol stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to xenobiotic stimulus	Epidermal growth factor receptor	Homo sapiens (human)
cellular response to dexamethasone stimulus	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
liver regeneration	Epidermal growth factor receptor	Homo sapiens (human)
cell-cell adhesion	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of protein kinase C activity	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of G1/S transition of mitotic cell cycle	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of non-canonical NF-kappaB signal transduction	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of prolactin secretion	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of miRNA transcription	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
negative regulation of cardiocyte differentiation	Epidermal growth factor receptor	Homo sapiens (human)
neurogenesis	Epidermal growth factor receptor	Homo sapiens (human)
multicellular organism development	Epidermal growth factor receptor	Homo sapiens (human)
positive regulation of kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Epidermal growth factor receptor	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell activation involved in immune response	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to virus	Interferon beta	Homo sapiens (human)
positive regulation of autophagy	Interferon beta	Homo sapiens (human)
cytokine-mediated signaling pathway	Interferon beta	Homo sapiens (human)
natural killer cell activation	Interferon beta	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT protein	Interferon beta	Homo sapiens (human)
cellular response to interferon-beta	Interferon beta	Homo sapiens (human)
B cell proliferation	Interferon beta	Homo sapiens (human)
negative regulation of viral genome replication	Interferon beta	Homo sapiens (human)
innate immune response	Interferon beta	Homo sapiens (human)
positive regulation of innate immune response	Interferon beta	Homo sapiens (human)
regulation of MHC class I biosynthetic process	Interferon beta	Homo sapiens (human)
negative regulation of T cell differentiation	Interferon beta	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Interferon beta	Homo sapiens (human)
defense response to virus	Interferon beta	Homo sapiens (human)
type I interferon-mediated signaling pathway	Interferon beta	Homo sapiens (human)
neuron cellular homeostasis	Interferon beta	Homo sapiens (human)
cellular response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
cellular response to virus	Interferon beta	Homo sapiens (human)
negative regulation of Lewy body formation	Interferon beta	Homo sapiens (human)
negative regulation of T-helper 2 cell cytokine production	Interferon beta	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell differentiation	Interferon beta	Homo sapiens (human)
natural killer cell activation involved in immune response	Interferon beta	Homo sapiens (human)
adaptive immune response	Interferon beta	Homo sapiens (human)
T cell activation involved in immune response	Interferon beta	Homo sapiens (human)
humoral immune response	Interferon beta	Homo sapiens (human)
positive regulation of T cell mediated cytotoxicity	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
adaptive immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of T cell anergy	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
defense response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
detection of bacterium	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of interleukin-12 production	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of interleukin-6 production	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protection from natural killer cell mediated cytotoxicity	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
innate immune response	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
regulation of dendritic cell differentiation	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
cellular response to amyloid-beta	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
protein phosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
axon guidance	High affinity nerve growth factor receptor	Homo sapiens (human)
learning or memory	High affinity nerve growth factor receptor	Homo sapiens (human)
circadian rhythm	High affinity nerve growth factor receptor	Homo sapiens (human)
negative regulation of cell population proliferation	High affinity nerve growth factor receptor	Homo sapiens (human)
response to xenobiotic stimulus	High affinity nerve growth factor receptor	Homo sapiens (human)
programmed cell death involved in cell development	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of neuron projection development	High affinity nerve growth factor receptor	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
olfactory nerve development	High affinity nerve growth factor receptor	Homo sapiens (human)
B cell differentiation	High affinity nerve growth factor receptor	Homo sapiens (human)
response to nutrient levels	High affinity nerve growth factor receptor	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
nerve growth factor signaling pathway	High affinity nerve growth factor receptor	Homo sapiens (human)
mechanoreceptor differentiation	High affinity nerve growth factor receptor	Homo sapiens (human)
negative regulation of apoptotic process	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of programmed cell death	High affinity nerve growth factor receptor	Homo sapiens (human)
negative regulation of neuron apoptotic process	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of GTPase activity	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of Ras protein signal transduction	High affinity nerve growth factor receptor	Homo sapiens (human)
protein autophosphorylation	High affinity nerve growth factor receptor	Homo sapiens (human)
neurotrophin TRK receptor signaling pathway	High affinity nerve growth factor receptor	Homo sapiens (human)
ephrin receptor signaling pathway	High affinity nerve growth factor receptor	Homo sapiens (human)
sympathetic nervous system development	High affinity nerve growth factor receptor	Homo sapiens (human)
response to axon injury	High affinity nerve growth factor receptor	Homo sapiens (human)
detection of temperature stimulus involved in sensory perception of pain	High affinity nerve growth factor receptor	Homo sapiens (human)
detection of mechanical stimulus involved in sensory perception of pain	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	High affinity nerve growth factor receptor	Homo sapiens (human)
neuron apoptotic process	High affinity nerve growth factor receptor	Homo sapiens (human)
response to hydrostatic pressure	High affinity nerve growth factor receptor	Homo sapiens (human)
response to electrical stimulus	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of synapse assembly	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of synaptic transmission, glutamatergic	High affinity nerve growth factor receptor	Homo sapiens (human)
Sertoli cell development	High affinity nerve growth factor receptor	Homo sapiens (human)
axonogenesis involved in innervation	High affinity nerve growth factor receptor	Homo sapiens (human)
behavioral response to formalin induced pain	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	High affinity nerve growth factor receptor	Homo sapiens (human)
cellular response to nicotine	High affinity nerve growth factor receptor	Homo sapiens (human)
cellular response to nerve growth factor stimulus	High affinity nerve growth factor receptor	Homo sapiens (human)
multicellular organism development	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of kinase activity	High affinity nerve growth factor receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	High affinity nerve growth factor receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	High affinity nerve growth factor receptor	Homo sapiens (human)
signal transduction	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
adenylate cyclase-activating G protein-coupled receptor signaling pathway	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
negative regulation of adenylate cyclase activity	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
G protein-coupled acetylcholine receptor signaling pathway	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
response to nutrient	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
cell population proliferation	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
positive regulation of cell population proliferation	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
positive regulation of cell migration	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
positive regulation of superoxide anion generation	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
positive regulation of urine volume	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
negative regulation of calcium ion-dependent exocytosis	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
positive regulation of insulin receptor signaling pathway	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
negative regulation of synaptic transmission	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
cell division	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
regulation of calcium ion transport	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
positive regulation of neural precursor cell proliferation	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
negative regulation of apoptotic signaling pathway	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
G protein-coupled adenosine receptor signaling pathway	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
gamma-aminobutyric acid signaling pathway	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
chromosome segregation	ADP/ATP translocase 2	Homo sapiens (human)
positive regulation of cell population proliferation	ADP/ATP translocase 2	Homo sapiens (human)
adenine transport	ADP/ATP translocase 2	Homo sapiens (human)
B cell differentiation	ADP/ATP translocase 2	Homo sapiens (human)
erythrocyte differentiation	ADP/ATP translocase 2	Homo sapiens (human)
regulation of mitochondrial membrane permeability	ADP/ATP translocase 2	Homo sapiens (human)
adenine nucleotide transport	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial ADP transmembrane transport	ADP/ATP translocase 2	Homo sapiens (human)
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	ADP/ATP translocase 2	Homo sapiens (human)
positive regulation of mitophagy	ADP/ATP translocase 2	Homo sapiens (human)
proton transmembrane transport	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial ATP transmembrane transport	ADP/ATP translocase 2	Homo sapiens (human)
cellular response to leukemia inhibitory factor	ADP/ATP translocase 2	Homo sapiens (human)
adaptive thermogenesis	ADP/ATP translocase 2	Homo sapiens (human)
adaptive immune response	Protein kinase C beta type	Homo sapiens (human)
chromatin remodeling	Protein kinase C beta type	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Protein kinase C beta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C beta type	Homo sapiens (human)
calcium ion transport	Protein kinase C beta type	Homo sapiens (human)
intracellular calcium ion homeostasis	Protein kinase C beta type	Homo sapiens (human)
apoptotic process	Protein kinase C beta type	Homo sapiens (human)
mitotic nuclear membrane disassembly	Protein kinase C beta type	Homo sapiens (human)
signal transduction	Protein kinase C beta type	Homo sapiens (human)
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
response to xenobiotic stimulus	Protein kinase C beta type	Homo sapiens (human)
response to glucose	Protein kinase C beta type	Homo sapiens (human)
regulation of glucose transmembrane transport	Protein kinase C beta type	Homo sapiens (human)
negative regulation of glucose transmembrane transport	Protein kinase C beta type	Homo sapiens (human)
regulation of dopamine secretion	Protein kinase C beta type	Homo sapiens (human)
dibenzo-p-dioxin metabolic process	Protein kinase C beta type	Homo sapiens (human)
positive regulation of vascular endothelial growth factor receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
positive regulation of insulin secretion	Protein kinase C beta type	Homo sapiens (human)
response to vitamin D	Protein kinase C beta type	Homo sapiens (human)
regulation of growth	Protein kinase C beta type	Homo sapiens (human)
B cell activation	Protein kinase C beta type	Homo sapiens (human)
positive regulation of odontogenesis of dentin-containing tooth	Protein kinase C beta type	Homo sapiens (human)
lipoprotein transport	Protein kinase C beta type	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Protein kinase C beta type	Homo sapiens (human)
post-translational protein modification	Protein kinase C beta type	Homo sapiens (human)
response to ethanol	Protein kinase C beta type	Homo sapiens (human)
positive regulation of angiogenesis	Protein kinase C beta type	Homo sapiens (human)
positive regulation of DNA-templated transcription	Protein kinase C beta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
B cell receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
positive regulation of B cell receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
cellular response to carbohydrate stimulus	Protein kinase C beta type	Homo sapiens (human)
presynaptic modulation of chemical synaptic transmission	Protein kinase C beta type	Homo sapiens (human)
regulation of synaptic vesicle exocytosis	Protein kinase C beta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C beta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C beta type	Homo sapiens (human)
positive regulation of MAP kinase activity	Insulin receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	Insulin receptor	Homo sapiens (human)
positive regulation of receptor internalization	Insulin receptor	Homo sapiens (human)
heart morphogenesis	Insulin receptor	Homo sapiens (human)
regulation of DNA-templated transcription	Insulin receptor	Homo sapiens (human)
protein phosphorylation	Insulin receptor	Homo sapiens (human)
receptor-mediated endocytosis	Insulin receptor	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Insulin receptor	Homo sapiens (human)
learning	Insulin receptor	Homo sapiens (human)
memory	Insulin receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Insulin receptor	Homo sapiens (human)
insulin receptor signaling pathway	Insulin receptor	Homo sapiens (human)
epidermis development	Insulin receptor	Homo sapiens (human)
male gonad development	Insulin receptor	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Insulin receptor	Homo sapiens (human)
male sex determination	Insulin receptor	Homo sapiens (human)
adrenal gland development	Insulin receptor	Homo sapiens (human)
positive regulation of cell migration	Insulin receptor	Homo sapiens (human)
exocrine pancreas development	Insulin receptor	Homo sapiens (human)
receptor internalization	Insulin receptor	Homo sapiens (human)
activation of protein kinase activity	Insulin receptor	Homo sapiens (human)
activation of protein kinase B activity	Insulin receptor	Homo sapiens (human)
cellular response to insulin stimulus	Insulin receptor	Homo sapiens (human)
glucose homeostasis	Insulin receptor	Homo sapiens (human)
positive regulation of protein-containing complex disassembly	Insulin receptor	Homo sapiens (human)
positive regulation of MAPK cascade	Insulin receptor	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	Insulin receptor	Homo sapiens (human)
positive regulation of glycogen biosynthetic process	Insulin receptor	Homo sapiens (human)
positive regulation of glycolytic process	Insulin receptor	Homo sapiens (human)
positive regulation of mitotic nuclear division	Insulin receptor	Homo sapiens (human)
positive regulation of DNA-templated transcription	Insulin receptor	Homo sapiens (human)
regulation of embryonic development	Insulin receptor	Homo sapiens (human)
positive regulation of glucose import	Insulin receptor	Homo sapiens (human)
symbiont entry into host cell	Insulin receptor	Homo sapiens (human)
protein autophosphorylation	Insulin receptor	Homo sapiens (human)
positive regulation of developmental growth	Insulin receptor	Homo sapiens (human)
positive regulation of meiotic cell cycle	Insulin receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Insulin receptor	Homo sapiens (human)
positive regulation of respiratory burst	Insulin receptor	Homo sapiens (human)
cellular response to growth factor stimulus	Insulin receptor	Homo sapiens (human)
dendritic spine maintenance	Insulin receptor	Homo sapiens (human)
amyloid-beta clearance	Insulin receptor	Homo sapiens (human)
transport across blood-brain barrier	Insulin receptor	Homo sapiens (human)
neuron projection maintenance	Insulin receptor	Homo sapiens (human)
regulation of female gonad development	Insulin receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Insulin receptor	Homo sapiens (human)
multicellular organism development	Insulin receptor	Homo sapiens (human)
positive regulation of kinase activity	Insulin receptor	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Lck	Homo sapiens (human)
intracellular zinc ion homeostasis	Tyrosine-protein kinase Lck	Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic process	Tyrosine-protein kinase Lck	Homo sapiens (human)
response to xenobiotic stimulus	Tyrosine-protein kinase Lck	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Lck	Homo sapiens (human)
hemopoiesis	Tyrosine-protein kinase Lck	Homo sapiens (human)
platelet activation	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell differentiation	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of heterotypic cell-cell adhesion	Tyrosine-protein kinase Lck	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Lck	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Tyrosine-protein kinase Lck	Homo sapiens (human)
Fc-gamma receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of T cell receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of T cell activation	Tyrosine-protein kinase Lck	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Lck	Homo sapiens (human)
release of sequestered calcium ion into cytosol	Tyrosine-protein kinase Lck	Homo sapiens (human)
regulation of lymphocyte activation	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of leukocyte cell-cell adhesion	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Lck	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
response to singlet oxygen	Tyrosine-protein kinase Fyn	Homo sapiens (human)
neuron migration	Tyrosine-protein kinase Fyn	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
heart process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
calcium ion transport	Tyrosine-protein kinase Fyn	Homo sapiens (human)
G protein-coupled glutamate receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
axon guidance	Tyrosine-protein kinase Fyn	Homo sapiens (human)
learning	Tyrosine-protein kinase Fyn	Homo sapiens (human)
feeding behavior	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of cell shape	Tyrosine-protein kinase Fyn	Homo sapiens (human)
gene expression	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of gene expression	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of hydrogen peroxide biosynthetic process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein ubiquitination	Tyrosine-protein kinase Fyn	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein catabolic process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
forebrain development	Tyrosine-protein kinase Fyn	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of protein ubiquitination	Tyrosine-protein kinase Fyn	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of protein catabolic process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase Fyn	Homo sapiens (human)
response to ethanol	Tyrosine-protein kinase Fyn	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
ephrin receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendrite morphogenesis	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
activated T cell proliferation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
modulation of chemical synaptic transmission	Tyrosine-protein kinase Fyn	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Fyn	Homo sapiens (human)
detection of mechanical stimulus involved in sensory perception of pain	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to hydrogen peroxide	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of protein targeting to membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendritic spine maintenance	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of protein localization to nucleus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of glutamate receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of dendritic spine maintenance	Tyrosine-protein kinase Fyn	Homo sapiens (human)
response to amyloid-beta	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to amyloid-beta	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to L-glutamate	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to glycine	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of protein localization to membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of calcium ion import across plasma membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
microtubule cytoskeleton organization	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA replication	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA repair	Cyclin-dependent kinase 1	Homo sapiens (human)
chromatin remodeling	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 1	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 1	Homo sapiens (human)
apoptotic process	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA damage response	Cyclin-dependent kinase 1	Homo sapiens (human)
mitotic nuclear membrane disassembly	Cyclin-dependent kinase 1	Homo sapiens (human)
centrosome cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
pronuclear fusion	Cyclin-dependent kinase 1	Homo sapiens (human)
response to xenobiotic stimulus	Cyclin-dependent kinase 1	Homo sapiens (human)
response to toxic substance	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of gene expression	Cyclin-dependent kinase 1	Homo sapiens (human)
negative regulation of gene expression	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of Schwann cell differentiation	Cyclin-dependent kinase 1	Homo sapiens (human)
response to amine	Cyclin-dependent kinase 1	Homo sapiens (human)
response to activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cell migration	Cyclin-dependent kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Cyclin-dependent kinase 1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Cyclin-dependent kinase 1	Homo sapiens (human)
chromosome condensation	Cyclin-dependent kinase 1	Homo sapiens (human)
epithelial cell differentiation	Cyclin-dependent kinase 1	Homo sapiens (human)
animal organ regeneration	Cyclin-dependent kinase 1	Homo sapiens (human)
protein localization to kinetochore	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of protein import into nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of circadian rhythm	Cyclin-dependent kinase 1	Homo sapiens (human)
negative regulation of apoptotic process	Cyclin-dependent kinase 1	Homo sapiens (human)
response to ethanol	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of DNA replication	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of embryonic development	Cyclin-dependent kinase 1	Homo sapiens (human)
response to cadmium ion	Cyclin-dependent kinase 1	Homo sapiens (human)
response to copper ion	Cyclin-dependent kinase 1	Homo sapiens (human)
symbiont entry into host cell	Cyclin-dependent kinase 1	Homo sapiens (human)
fibroblast proliferation	Cyclin-dependent kinase 1	Homo sapiens (human)
rhythmic process	Cyclin-dependent kinase 1	Homo sapiens (human)
response to axon injury	Cyclin-dependent kinase 1	Homo sapiens (human)
cell division	Cyclin-dependent kinase 1	Homo sapiens (human)
ventricular cardiac muscle cell development	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of mitotic sister chromatid segregation	Cyclin-dependent kinase 1	Homo sapiens (human)
protein-containing complex assembly	Cyclin-dependent kinase 1	Homo sapiens (human)
cellular response to hydrogen peroxide	Cyclin-dependent kinase 1	Homo sapiens (human)
ERK1 and ERK2 cascade	Cyclin-dependent kinase 1	Homo sapiens (human)
cellular response to organic cyclic compound	Cyclin-dependent kinase 1	Homo sapiens (human)
Golgi disassembly	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of protein localization to nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of attachment of mitotic spindle microtubules to kinetochore	Cyclin-dependent kinase 1	Homo sapiens (human)
microtubule cytoskeleton organization involved in mitosis	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of mitochondrial ATP synthesis coupled electron transport	Cyclin-dependent kinase 1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Cyclin-dependent kinase 1	Homo sapiens (human)
protein deubiquitination	Cyclin-dependent kinase 1	Homo sapiens (human)
glycogen metabolic process	Glycogen phosphorylase, liver form	Homo sapiens (human)
5-phosphoribose 1-diphosphate biosynthetic process	Glycogen phosphorylase, liver form	Homo sapiens (human)
response to bacterium	Glycogen phosphorylase, liver form	Homo sapiens (human)
glucose homeostasis	Glycogen phosphorylase, liver form	Homo sapiens (human)
necroptotic process	Glycogen phosphorylase, liver form	Homo sapiens (human)
glycogen catabolic process	Glycogen phosphorylase, liver form	Homo sapiens (human)
microtubule bundle formation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
centrosome cycle	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell shape	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell adhesion	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
positive regulation of microtubule polymerization	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell population proliferation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of mast cell degranulation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell differentiation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
positive regulation of myeloid cell differentiation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
positive regulation of monocyte differentiation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
myoblast proliferation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cardiac muscle cell proliferation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of vesicle-mediated transport	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cellular response to vitamin D	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
regulation of cell motility	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
chemotaxis	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
purine ribonucleoside salvage	Adenine phosphoribosyltransferase	Homo sapiens (human)
grooming behavior	Adenine phosphoribosyltransferase	Homo sapiens (human)
GMP salvage	Adenine phosphoribosyltransferase	Homo sapiens (human)
IMP salvage	Adenine phosphoribosyltransferase	Homo sapiens (human)
AMP salvage	Adenine phosphoribosyltransferase	Homo sapiens (human)
adenine salvage	Adenine phosphoribosyltransferase	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Yes	Homo sapiens (human)
regulation of glucose transmembrane transport	Tyrosine-protein kinase Yes	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Yes	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein modification process	Tyrosine-protein kinase Yes	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Yes	Homo sapiens (human)
regulation of vascular permeability	Tyrosine-protein kinase Yes	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Tyrosine-protein kinase Yes	Homo sapiens (human)
ephrin receptor signaling pathway	Tyrosine-protein kinase Yes	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Yes	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Yes	Homo sapiens (human)
cellular response to retinoic acid	Tyrosine-protein kinase Yes	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Tyrosine-protein kinase Yes	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Yes	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Yes	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Yes	Homo sapiens (human)
DNA damage checkpoint signaling	Tyrosine-protein kinase Lyn	Homo sapiens (human)
B cell homeostasis	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of cytokine production	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
hematopoietic progenitor cell differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc receptor mediated stimulatory signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
tolerance induction to self antigen	Tyrosine-protein kinase Lyn	Homo sapiens (human)
histamine secretion by mast cell	Tyrosine-protein kinase Lyn	Homo sapiens (human)
platelet degranulation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of myeloid leukocyte differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
immune response-regulating cell surface receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc receptor mediated inhibitory signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of B cell apoptotic process	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
DNA damage response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to sterol depletion	Tyrosine-protein kinase Lyn	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of cell population proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of cell population proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to xenobiotic stimulus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to toxic substance	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to hormone	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to carbohydrate	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase Lyn	Homo sapiens (human)
oligodendrocyte development	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to organic cyclic compound	Tyrosine-protein kinase Lyn	Homo sapiens (human)
fatty acid transport	Tyrosine-protein kinase Lyn	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
erythrocyte differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
eosinophil differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of cell migration	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of B cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to insulin	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of mast cell activation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of cell adhesion mediated by integrin	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of toll-like receptor 2 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of toll-like receptor 4 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cellular response to heat	Tyrosine-protein kinase Lyn	Homo sapiens (human)
interleukin-5-mediated signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Lyn	Homo sapiens (human)
C-X-C chemokine receptor CXCR4 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to amino acid	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of mast cell degranulation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of MAP kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of MAPK cascade	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of erythrocyte differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ephrin receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to axon injury	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of immune response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of B cell receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of glial cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of Fc receptor mediated stimulatory signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of oligodendrocyte progenitor proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of mast cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of mast cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cellular response to retinoic acid	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of monocyte chemotaxis	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of platelet aggregation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
dendritic cell differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of intracellular signal transduction	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of dendritic cell apoptotic process	Tyrosine-protein kinase Lyn	Homo sapiens (human)
neuron projection development	Tyrosine-protein kinase Lyn	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
MAPK cascade	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
ureteric bud development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
neural crest cell migration	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
embryonic epithelial tube formation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
protein phosphorylation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
homophilic cell adhesion via plasma membrane adhesion molecules	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
neuron cell-cell adhesion	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
signal transduction	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
axon guidance	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
posterior midgut development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
response to xenobiotic stimulus	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of gene expression	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of neuron projection development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of neuron maturation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
regulation of cell adhesion	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of cell migration	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT protein	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
membrane protein proteolysis	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of cell adhesion mediated by integrin	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
ureter maturation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
glial cell-derived neurotrophic factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
neuron maturation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of MAPK cascade	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of cell size	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of DNA-templated transcription	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
response to pain	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
enteric nervous system development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
regulation of axonogenesis	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
retina development in camera-type eye	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
innervation	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
Peyer's patch morphogenesis	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
cellular response to retinoic acid	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of metanephric glomerulus development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
lymphocyte migration into lymphoid organs	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
GDF15-GFRAL signaling pathway	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
positive regulation of kinase activity	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
multicellular organism development	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cardiac atrium development	Insulin-like growth factor 1 receptor	Homo sapiens (human)
immune response	Insulin-like growth factor 1 receptor	Homo sapiens (human)
signal transduction	Insulin-like growth factor 1 receptor	Homo sapiens (human)
axonogenesis	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor signaling pathway	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of muscle cell apoptotic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cerebellum development	Insulin-like growth factor 1 receptor	Homo sapiens (human)
hippocampus development	Insulin-like growth factor 1 receptor	Homo sapiens (human)
establishment of cell polarity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of cell migration	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of cytokinesis	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to vitamin E	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of osteoblast proliferation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to zinc ion starvation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to nicotine	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of apoptotic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of protein-containing complex disassembly	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to alkaloid	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of MAPK cascade	Insulin-like growth factor 1 receptor	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Insulin-like growth factor 1 receptor	Homo sapiens (human)
estrous cycle	Insulin-like growth factor 1 receptor	Homo sapiens (human)
transcytosis	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to ethanol	Insulin-like growth factor 1 receptor	Homo sapiens (human)
regulation of JNK cascade	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein autophosphorylation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of axon regeneration	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of DNA metabolic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to mechanical stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to estradiol stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to progesterone stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to testosterone stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to dexamethasone stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of steroid hormone biosynthetic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular senescence	Insulin-like growth factor 1 receptor	Homo sapiens (human)
dendritic spine maintenance	Insulin-like growth factor 1 receptor	Homo sapiens (human)
amyloid-beta clearance	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of cold-induced thermogenesis	Insulin-like growth factor 1 receptor	Homo sapiens (human)
response to L-glutamate	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of hepatocyte apoptotic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to aldosterone	Insulin-like growth factor 1 receptor	Homo sapiens (human)
negative regulation of cholangiocyte apoptotic process	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to angiotensin	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to amyloid-beta	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to insulin-like growth factor stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
multicellular organism development	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of kinase activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cellular response to glucose stimulus	Insulin-like growth factor 1 receptor	Homo sapiens (human)
positive regulation of MAPK cascade	Insulin-like growth factor 1 receptor	Homo sapiens (human)
cotranslational protein targeting to membrane	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
intracellular protein transport	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
protein targeting to ER	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
mitochondrial electron transport, ubiquinol to cytochrome c	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
response to glucagon	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
cellular respiration	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
proton transmembrane transport	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
endothelial cell morphogenesis	Hepatocyte growth factor receptor	Homo sapiens (human)
signal transduction	Hepatocyte growth factor receptor	Homo sapiens (human)
cell surface receptor signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of autophagy	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of microtubule polymerization	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of Rho protein signal transduction	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Hepatocyte growth factor receptor	Homo sapiens (human)
hepatocyte growth factor receptor signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
branching morphogenesis of an epithelial tube	Hepatocyte growth factor receptor	Homo sapiens (human)
positive chemotaxis	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of stress fiber assembly	Hepatocyte growth factor receptor	Homo sapiens (human)
excitatory postsynaptic potential	Hepatocyte growth factor receptor	Homo sapiens (human)
establishment of skin barrier	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of thrombin-activated receptor signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
semaphorin-plexin signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of hydrogen peroxide-mediated programmed cell death	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of guanyl-nucleotide exchange factor activity	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Hepatocyte growth factor receptor	Homo sapiens (human)
liver development	Hepatocyte growth factor receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
phagocytosis	Hepatocyte growth factor receptor	Homo sapiens (human)
multicellular organism development	Hepatocyte growth factor receptor	Homo sapiens (human)
neuron differentiation	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of kinase activity	Hepatocyte growth factor receptor	Homo sapiens (human)
cell migration	Hepatocyte growth factor receptor	Homo sapiens (human)
pancreas development	Hepatocyte growth factor receptor	Homo sapiens (human)
nervous system development	Hepatocyte growth factor receptor	Homo sapiens (human)
leukocyte migration involved in immune response	Tyrosine-protein kinase HCK	Homo sapiens (human)
innate immune response-activating signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase HCK	Homo sapiens (human)
inflammatory response	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase HCK	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
mesoderm development	Tyrosine-protein kinase HCK	Homo sapiens (human)
positive regulation of cell population proliferation	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of cell shape	Tyrosine-protein kinase HCK	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
positive regulation of actin filament polymerization	Tyrosine-protein kinase HCK	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of actin cytoskeleton organization	Tyrosine-protein kinase HCK	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase HCK	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase HCK	Homo sapiens (human)
negative regulation of apoptotic process	Tyrosine-protein kinase HCK	Homo sapiens (human)
leukocyte degranulation	Tyrosine-protein kinase HCK	Homo sapiens (human)
respiratory burst after phagocytosis	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of inflammatory response	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of phagocytosis	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of DNA-binding transcription factor activity	Tyrosine-protein kinase HCK	Homo sapiens (human)
type II interferon-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of podosome assembly	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase HCK	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
signal transduction	Platelet-derived growth factor receptor beta	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cell population proliferation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of phospholipase C activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of smooth muscle cell migration	Platelet-derived growth factor receptor beta	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cell migration	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of phosphoprotein phosphatase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
regulation of actin cytoskeleton organization	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell migration involved in vasculogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor-beta signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
aorta morphogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of MAP kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of mitotic nuclear division	Platelet-derived growth factor receptor beta	Homo sapiens (human)
phosphatidylinositol metabolic process	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein autophosphorylation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of chemotaxis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cardiac myofibril assembly	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell chemotaxis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell migration involved in coronary angiogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
retina vasculature development in camera-type eye	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Platelet-derived growth factor receptor beta	Homo sapiens (human)
smooth muscle cell chemotaxis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
metanephric glomerular mesangial cell proliferation involved in metanephros development	Platelet-derived growth factor receptor beta	Homo sapiens (human)
metanephric glomerular capillary formation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of calcium ion import	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of DNA biosynthetic process	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
angiogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
multicellular organism development	Platelet-derived growth factor receptor beta	Homo sapiens (human)
regulation of TOR signaling	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
regulation of proteasomal ubiquitin-dependent protein catabolic process	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protein modification process	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
ovarian follicle development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
myeloid progenitor cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
lymphoid progenitor cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
immature B cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
mast cell chemotaxis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of dendritic cell cytokine production	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
glycosphingolipid metabolic process	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
inflammatory response	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
signal transduction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
spermatogenesis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
spermatid development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
germ cell migration	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
regulation of cell shape	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
visual learning	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
male gonad development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of phospholipase C activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cytokine-mediated signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
stem cell population maintenance	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
lamellipodium assembly	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
actin cytoskeleton organization	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
hemopoiesis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
T cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
erythrocyte differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
melanocyte differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of pseudopodium assembly	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of mast cell cytokine production	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
somatic stem cell population maintenance	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
embryonic hemopoiesis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
ectopic germ cell programmed cell death	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
intracellular signal transduction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
hematopoietic stem cell migration	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
megakaryocyte development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
Fc receptor signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
Kit signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
erythropoietin-mediated signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
regulation of cell population proliferation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
negative regulation of programmed cell death	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
mast cell degranulation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of MAPK cascade	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
pigmentation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
tongue development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of Notch signaling pathway	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
response to cadmium ion	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein autophosphorylation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of long-term neuronal synaptic plasticity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
digestive tract development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
stem cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
epithelial cell proliferation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
detection of mechanical stimulus involved in sensory perception of sound	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
negative regulation of developmental process	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cell chemotaxis	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
mast cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
mast cell proliferation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of mast cell proliferation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
melanocyte migration	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
melanocyte adhesion	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of pyloric antrum smooth muscle contraction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
regulation of bile acid metabolic process	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of colon smooth muscle contraction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of small intestine smooth muscle contraction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
negative regulation of reproductive process	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of cell migration	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
positive regulation of MAP kinase activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
multicellular organism development	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
B cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
hematopoietic progenitor cell differentiation	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
glycogen catabolic process	Glycogen phosphorylase, brain form	Homo sapiens (human)
negative regulation of cellular extravasation	Breakpoint cluster region protein	Homo sapiens (human)
renal system process	Breakpoint cluster region protein	Homo sapiens (human)
protein phosphorylation	Breakpoint cluster region protein	Homo sapiens (human)
phagocytosis	Breakpoint cluster region protein	Homo sapiens (human)
signal transduction	Breakpoint cluster region protein	Homo sapiens (human)
small GTPase-mediated signal transduction	Breakpoint cluster region protein	Homo sapiens (human)
brain development	Breakpoint cluster region protein	Homo sapiens (human)
actin cytoskeleton organization	Breakpoint cluster region protein	Homo sapiens (human)
keratinocyte differentiation	Breakpoint cluster region protein	Homo sapiens (human)
regulation of Rho protein signal transduction	Breakpoint cluster region protein	Homo sapiens (human)
inner ear morphogenesis	Breakpoint cluster region protein	Homo sapiens (human)
regulation of vascular permeability	Breakpoint cluster region protein	Homo sapiens (human)
neutrophil degranulation	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of neutrophil degranulation	Breakpoint cluster region protein	Homo sapiens (human)
focal adhesion assembly	Breakpoint cluster region protein	Homo sapiens (human)
homeostasis of number of cells	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of inflammatory response	Breakpoint cluster region protein	Homo sapiens (human)
positive regulation of phagocytosis	Breakpoint cluster region protein	Homo sapiens (human)
modulation of chemical synaptic transmission	Breakpoint cluster region protein	Homo sapiens (human)
neuromuscular process controlling balance	Breakpoint cluster region protein	Homo sapiens (human)
regulation of small GTPase mediated signal transduction	Breakpoint cluster region protein	Homo sapiens (human)
regulation of cell cycle	Breakpoint cluster region protein	Homo sapiens (human)
definitive hemopoiesis	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of respiratory burst	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of blood vessel remodeling	Breakpoint cluster region protein	Homo sapiens (human)
intracellular protein transmembrane transport	Breakpoint cluster region protein	Homo sapiens (human)
cellular response to lipopolysaccharide	Breakpoint cluster region protein	Homo sapiens (human)
activation of GTPase activity	Breakpoint cluster region protein	Homo sapiens (human)
macrophage migration	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of macrophage migration	Breakpoint cluster region protein	Homo sapiens (human)
negative regulation of reactive oxygen species metabolic process	Breakpoint cluster region protein	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
regulation of transmembrane transporter activity	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
negative regulation of DNA-binding transcription factor activity	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
negative regulation of innate immune response	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
vitamin D receptor signaling pathway	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cellular response to type II interferon	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of brown fat cell differentiation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
regulation of hematopoietic stem cell proliferation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of TORC1 signaling	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of cardioblast proliferation	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cellular detoxification	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 1	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Fibroblast growth factor receptor 1	Homo sapiens (human)
MAPK cascade	Fibroblast growth factor receptor 1	Homo sapiens (human)
skeletal system development	Fibroblast growth factor receptor 1	Homo sapiens (human)
angiogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
ureteric bud development	Fibroblast growth factor receptor 1	Homo sapiens (human)
in utero embryonic development	Fibroblast growth factor receptor 1	Homo sapiens (human)
organ induction	Fibroblast growth factor receptor 1	Homo sapiens (human)
neuron migration	Fibroblast growth factor receptor 1	Homo sapiens (human)
epithelial to mesenchymal transition	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
chondrocyte differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
protein phosphorylation	Fibroblast growth factor receptor 1	Homo sapiens (human)
sensory perception of sound	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of cell population proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 1	Homo sapiens (human)
mesenchymal cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
gene expression	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of phospholipase activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of phospholipase C activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of phosphate transport	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of neuron projection development	Fibroblast growth factor receptor 1	Homo sapiens (human)
cell migration	Fibroblast growth factor receptor 1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Fibroblast growth factor receptor 1	Homo sapiens (human)
ventricular zone neuroblast division	Fibroblast growth factor receptor 1	Homo sapiens (human)
cell projection assembly	Fibroblast growth factor receptor 1	Homo sapiens (human)
embryonic limb morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
midbrain development	Fibroblast growth factor receptor 1	Homo sapiens (human)
neuron projection development	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	Fibroblast growth factor receptor 1	Homo sapiens (human)
inner ear morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
outer ear morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
middle ear morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
chordate embryonic development	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of MAP kinase activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of MAPK cascade	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Fibroblast growth factor receptor 1	Homo sapiens (human)
cellular response to fibroblast growth factor stimulus	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of cell differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of neuron differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
protein autophosphorylation	Fibroblast growth factor receptor 1	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Fibroblast growth factor receptor 1	Homo sapiens (human)
paraxial mesoderm development	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of lateral mesodermal cell fate specification	Fibroblast growth factor receptor 1	Homo sapiens (human)
cell maturation	Fibroblast growth factor receptor 1	Homo sapiens (human)
skeletal system morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
stem cell differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Fibroblast growth factor receptor 1	Homo sapiens (human)
calcium ion homeostasis	Fibroblast growth factor receptor 1	Homo sapiens (human)
cardiac muscle cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
auditory receptor cell development	Fibroblast growth factor receptor 1	Homo sapiens (human)
branching involved in salivary gland morphogenesis	Fibroblast growth factor receptor 1	Homo sapiens (human)
lung-associated mesenchyme development	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	Fibroblast growth factor receptor 1	Homo sapiens (human)
vitamin D3 metabolic process	Fibroblast growth factor receptor 1	Homo sapiens (human)
diphosphate metabolic process	Fibroblast growth factor receptor 1	Homo sapiens (human)
cementum mineralization	Fibroblast growth factor receptor 1	Homo sapiens (human)
stem cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	Fibroblast growth factor receptor 1	Homo sapiens (human)
negative regulation of fibroblast growth factor production	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of mitotic cell cycle DNA replication	Fibroblast growth factor receptor 1	Homo sapiens (human)
response to sodium phosphate	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of vascular endothelial cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of stem cell proliferation	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of parathyroid hormone secretion	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Fibroblast growth factor receptor 1	Homo sapiens (human)
regulation of extrinsic apoptotic signaling pathway in absence of ligand	Fibroblast growth factor receptor 1	Homo sapiens (human)
multicellular organism development	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of cell differentiation	Fibroblast growth factor receptor 1	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Fibroblast growth factor receptor 1	Homo sapiens (human)
positive regulation of kinase activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 4	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 4	Homo sapiens (human)
positive regulation of cell population proliferation	Cyclin-dependent kinase 4	Homo sapiens (human)
response to xenobiotic stimulus	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of gene expression	Cyclin-dependent kinase 4	Homo sapiens (human)
positive regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 4	Homo sapiens (human)
positive regulation of fibroblast proliferation	Cyclin-dependent kinase 4	Homo sapiens (human)
cell division	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of transcription initiation by RNA polymerase II	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of type B pancreatic cell proliferation	Cyclin-dependent kinase 4	Homo sapiens (human)
cellular response to lipopolysaccharide	Cyclin-dependent kinase 4	Homo sapiens (human)
cellular response to interleukin-4	Cyclin-dependent kinase 4	Homo sapiens (human)
cellular response to phorbol 13-acetate 12-myristate	Cyclin-dependent kinase 4	Homo sapiens (human)
cellular response to ionomycin	Cyclin-dependent kinase 4	Homo sapiens (human)
response to organic substance	Cyclin-dependent kinase 4	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 4	Homo sapiens (human)
signal transduction	Cyclin-dependent kinase 4	Homo sapiens (human)
apoptotic process	ADP/ATP translocase 3	Homo sapiens (human)
mitochondrial ADP transmembrane transport	ADP/ATP translocase 3	Homo sapiens (human)
mitochondrial ATP transmembrane transport	ADP/ATP translocase 3	Homo sapiens (human)
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	ADP/ATP translocase 3	Homo sapiens (human)
GMP biosynthetic process	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
GTP biosynthetic process	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
circadian rhythm	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
lymphocyte proliferation	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
cellular response to interleukin-4	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
'de novo' XMP biosynthetic process	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
primary ovarian follicle growth	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of cytokine production	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
signal complex assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
integrin-mediated signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
spermatogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
learning or memory	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to xenobiotic stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to mechanical stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to acidic pH	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of gene expression	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of epithelial cell migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of epithelial cell migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of glucose metabolic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein processing	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
skeletal muscle cell proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of smooth muscle cell migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
macroautophagy	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of cell-cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
platelet activation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
forebrain development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
T cell costimulation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein destabilization	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to nutrient levels	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of telomere maintenance via telomerase	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to insulin stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of intracellular estrogen receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of integrin activation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of toll-like receptor 3 signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
adherens junction organization	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of dephosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of hippo signaling	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
intracellular signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
entry of bacterium into host cell	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
osteoclast development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ERBB2 signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
angiotensin-activated signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
odontogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of apoptotic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of apoptotic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of vascular permeability	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
stress fiber assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
transcytosis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of bone resorption	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
bone resorption	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of Notch signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of bone resorption	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of Ras protein signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of insulin receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein autophosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
neurotrophin TRK receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ephrin receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
focal adhesion assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
oogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
progesterone receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
leukocyte migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of small GTPase mediated signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein transport	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to mineralocorticoid	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
myoblast proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to electrical stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of focal adhesion assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of mitochondrial depolarization	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of telomerase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
uterus development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
branching involved in mammary gland duct morphogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of cell projection assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
intestinal epithelial cell development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
interleukin-6-mediated signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to hydrogen peroxide	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to interleukin-1	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to lipopolysaccharide	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to peptide hormone stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to progesterone stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to fatty acid	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to hypoxia	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to fluid shear stress	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of podosome assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
DNA biosynthetic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell-cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein localization to nucleus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of non-membrane spanning protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of TORC1 signaling	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to prolactin	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of male germ cell proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of ovarian follicle development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of lamellipodium morphogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of platelet-derived growth factor receptor-beta signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of early endosome to late endosome transport	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of anoikis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of caveolin-mediated endocytosis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell differentiation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
innate immune response	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
symbiont entry into host cell	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of protein phosphorylation	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
intracellular signal transduction	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
negative regulation of cAMP/PKA signal transduction	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
negative regulation of cAMP-dependent protein kinase activity	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
myeloid progenitor cell differentiation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
visual learning	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
animal organ morphogenesis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of gene expression	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of fibroblast migration	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of glucose transmembrane transport	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
synaptic vesicle exocytosis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
thyroid gland development	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
T cell differentiation in thymus	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
somatic stem cell population maintenance	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
regulation of cell population proliferation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
stress fiber assembly	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
CD4-positive, alpha-beta T cell differentiation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
response to peptide hormone	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of neuron apoptotic process	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
regulation of T cell differentiation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
thymus development	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of axon regeneration	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of axonogenesis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
T cell receptor signaling pathway	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of stress fiber assembly	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
response to cAMP	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
long-term synaptic potentiation	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
head morphogenesis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
face development	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
ERK1 and ERK2 cascade	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cellular response to calcium ion	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cellular response to xenobiotic stimulus	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
endothelial cell apoptotic process	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
establishment of protein localization to membrane	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreading	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cellular response to nerve growth factor stimulus	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of synaptic vesicle exocytosis	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
glycogen metabolic process	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
glycogen biosynthetic process	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
glycogen catabolic process	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
generation of precursor metabolites and energy	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
protein phosphorylation	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
positive regulation of glycogen catabolic process	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
quinone catabolic process	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
cellular response to reactive oxygen species	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
luteinization	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
in utero embryonic development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell activation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
hematopoietic progenitor cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
estrogen metabolic process	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of cell population proliferation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
negative regulation of platelet activation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of phospholipase C activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
signal transduction involved in regulation of gene expression	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
extracellular matrix organization	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
lung development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
adrenal gland development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of cell migration	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
male genitalia development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
regulation of actin cytoskeleton organization	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
Leydig cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor receptor-alpha signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
wound healing	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
odontogenesis of dentin-containing tooth	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein autophosphorylation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of fibroblast proliferation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
embryonic digestive tract morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
embryonic cranial skeleton morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
embryonic skeletal system morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
white fat cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of chemotaxis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cardiac myofibril assembly	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
roof of mouth development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
face morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell chemotaxis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
retina vasculature development in camera-type eye	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet aggregation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cellular response to amino acid stimulus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
metanephric glomerular capillary formation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
regulation of mesenchymal stem cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of kinase activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
multicellular organism development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
microtubule cytoskeleton organization	Tyrosine-protein kinase Fer	Homo sapiens (human)
regulation of protein phosphorylation	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Fer	Homo sapiens (human)
tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase Fer	Homo sapiens (human)
germ cell development	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of cell population proliferation	Tyrosine-protein kinase Fer	Homo sapiens (human)
insulin receptor signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
regulation of lamellipodium assembly	Tyrosine-protein kinase Fer	Homo sapiens (human)
regulation of fibroblast migration	Tyrosine-protein kinase Fer	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fer	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
actin cytoskeleton organization	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of cell migration	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of actin filament polymerization	Tyrosine-protein kinase Fer	Homo sapiens (human)
response to lipopolysaccharide	Tyrosine-protein kinase Fer	Homo sapiens (human)
negative regulation of mast cell activation involved in immune response	Tyrosine-protein kinase Fer	Homo sapiens (human)
adherens junction assembly	Tyrosine-protein kinase Fer	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Tyrosine-protein kinase Fer	Homo sapiens (human)
cellular response to reactive oxygen species	Tyrosine-protein kinase Fer	Homo sapiens (human)
extracellular matrix-cell signaling	Tyrosine-protein kinase Fer	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Fer	Homo sapiens (human)
cellular response to macrophage colony-stimulating factor stimulus	Tyrosine-protein kinase Fer	Homo sapiens (human)
response to platelet-derived growth factor	Tyrosine-protein kinase Fer	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
Kit signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
regulation of epidermal growth factor receptor signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
cell-cell adhesion mediated by cadherin	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase Fer	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
diapedesis	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Tyrosine-protein kinase Fer	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase Fer	Homo sapiens (human)
Sertoli cell development	Tyrosine-protein kinase Fer	Homo sapiens (human)
interleukin-6-mediated signaling pathway	Tyrosine-protein kinase Fer	Homo sapiens (human)
seminiferous tubule development	Tyrosine-protein kinase Fer	Homo sapiens (human)
adherens junction disassembly	Tyrosine-protein kinase Fer	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase Fer	Homo sapiens (human)
chemotaxis	Tyrosine-protein kinase Fer	Homo sapiens (human)
angiogenesis	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Protein kinase C alpha type	Homo sapiens (human)
desmosome assembly	Protein kinase C alpha type	Homo sapiens (human)
chromatin remodeling	Protein kinase C alpha type	Homo sapiens (human)
protein phosphorylation	Protein kinase C alpha type	Homo sapiens (human)
mitotic nuclear membrane disassembly	Protein kinase C alpha type	Homo sapiens (human)
cell adhesion	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of endothelial cell migration	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of cardiac muscle hypertrophy	Protein kinase C alpha type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C alpha type	Homo sapiens (human)
peptidyl-threonine phosphorylation	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of cell migration	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of lipopolysaccharide-mediated signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C alpha type	Homo sapiens (human)
regulation of mRNA stability	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Protein kinase C alpha type	Homo sapiens (human)
post-translational protein modification	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of macrophage differentiation	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of angiogenesis	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of bone resorption	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of cell adhesion	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of mitotic cell cycle	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Protein kinase C alpha type	Homo sapiens (human)
response to interleukin-1	Protein kinase C alpha type	Homo sapiens (human)
regulation of platelet aggregation	Protein kinase C alpha type	Homo sapiens (human)
apoptotic signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of angiotensin-activated signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of dense core granule biogenesis	Protein kinase C alpha type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of insulin secretion	Protein kinase C alpha type	Homo sapiens (human)
mesoderm formation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
neural tube closure	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of heart rate	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
renal water homeostasis	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
mRNA processing	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein phosphorylation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein export from nucleus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
adenylate cyclase-activating G protein-coupled receptor signaling pathway	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of macroautophagy	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
peptidyl-serine phosphorylation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytokine-mediated signaling pathway	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
positive regulation of insulin secretion	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
negative regulation of interleukin-2 production	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
high-density lipoprotein particle assembly	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to heat	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
mitochondrial protein catabolic process	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of osteoblast differentiation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
positive regulation of gluconeogenesis	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
negative regulation of smoothened signaling pathway	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
positive regulation of protein export from nucleus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
sperm capacitation	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
positive regulation of calcium-mediated signaling	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of cell cycle	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of cardiac muscle contraction	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of proteasomal protein catabolic process	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to cold	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of protein processing	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to glucose stimulus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to parathyroid hormone stimulus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to glucagon stimulus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cellular response to epinephrine stimulus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cell communication by electrical coupling involved in cardiac conduction	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
postsynaptic modulation of chemical synaptic transmission	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of cardiac conduction	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
negative regulation of TORC1 signaling	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
negative regulation of glycolytic process through fructose-6-phosphate	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein localization to lipid droplet	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
regulation of bicellular tight junction assembly	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein kinase A signaling	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
angiogenesis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
monocyte chemotaxis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of cell population proliferation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of phospholipase C activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
cell migration	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
cell differentiation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of cell migration	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
vascular endothelial growth factor receptor-1 signaling pathway	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of MAP kinase activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of MAPK cascade	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of angiogenesis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
protein autophosphorylation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
blood vessel morphogenesis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
embryonic morphogenesis	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
negative regulation of vascular endothelial cell proliferation	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
hyaloid vascular plexus regression	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
multicellular organism development	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
positive regulation of kinase activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
response to hypoxia	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
in utero embryonic development	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription-coupled nucleotide-excision repair	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
nucleotide-excision repair	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
regulation of transcription by RNA polymerase II	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription elongation by RNA polymerase I	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription by RNA polymerase II	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription initiation at RNA polymerase II promoter	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
apoptotic process	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
response to oxidative stress	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
chromosome segregation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
determination of adult lifespan	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
UV protection	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
post-embryonic development	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
spinal cord development	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
extracellular matrix organization	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
bone mineralization	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
central nervous system myelin formation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
DNA duplex unwinding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
multicellular organism growth	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
hair cell differentiation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
embryonic cleavage	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
erythrocyte maturation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
embryonic organ development	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
hair follicle maturation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
hematopoietic stem cell differentiation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
hematopoietic stem cell proliferation	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
intrinsic apoptotic signaling pathway by p53 class mediator	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
regulation of mitotic cell cycle phase transition	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
positive regulation of mitotic recombination	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
double-strand break repair	Casein kinase II subunit alpha'	Homo sapiens (human)
apoptotic process	Casein kinase II subunit alpha'	Homo sapiens (human)
spermatogenesis	Casein kinase II subunit alpha'	Homo sapiens (human)
Wnt signaling pathway	Casein kinase II subunit alpha'	Homo sapiens (human)
cerebral cortex development	Casein kinase II subunit alpha'	Homo sapiens (human)
negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Casein kinase II subunit alpha'	Homo sapiens (human)
liver regeneration	Casein kinase II subunit alpha'	Homo sapiens (human)
regulation of mitophagy	Casein kinase II subunit alpha'	Homo sapiens (human)
positive regulation of protein targeting to mitochondrion	Casein kinase II subunit alpha'	Homo sapiens (human)
regulation of chromosome separation	Casein kinase II subunit alpha'	Homo sapiens (human)
negative regulation of apoptotic signaling pathway	Casein kinase II subunit alpha'	Homo sapiens (human)
peptidyl-threonine phosphorylation	Casein kinase II subunit alpha'	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase II subunit alpha'	Homo sapiens (human)
peptidyl-cysteine methylation	Ras-related protein Rab-6A	Homo sapiens (human)
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	Ras-related protein Rab-6A	Homo sapiens (human)
antigen processing and presentation	Ras-related protein Rab-6A	Homo sapiens (human)
neuron projection development	Ras-related protein Rab-6A	Homo sapiens (human)
protein localization to Golgi apparatus	Ras-related protein Rab-6A	Homo sapiens (human)
early endosome to Golgi transport	Ras-related protein Rab-6A	Homo sapiens (human)
minus-end-directed organelle transport along microtubule	Ras-related protein Rab-6A	Homo sapiens (human)
protein localization to Golgi membrane	Ras-related protein Rab-6A	Homo sapiens (human)
intracellular protein transport	Ras-related protein Rab-6A	Homo sapiens (human)
intra-Golgi vesicle-mediated transport	Ras-related protein Rab-6A	Homo sapiens (human)
retrograde transport, endosome to Golgi	Ras-related protein Rab-6A	Homo sapiens (human)
GMP biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
'de novo' IMP biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
purine nucleobase biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
'de novo' AMP biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
'de novo' XMP biosynthetic process	Multifunctional protein ADE2	Homo sapiens (human)
renal water homeostasis	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
spermatogenesis	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
male gonad development	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
high-density lipoprotein particle assembly	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
protein kinase A signaling	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
neural tube closure	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
renal water homeostasis	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein phosphorylation	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
signal transduction	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
high-density lipoprotein particle assembly	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
negative regulation of smoothened signaling pathway	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
regulation of protein processing	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
negative regulation of TORC1 signaling	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein kinase A signaling	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
generation of precursor metabolites and energy	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme A biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme B biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
cholesterol metabolic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to xenobiotic stimulus	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to light stimulus	Ferrochelatase, mitochondrial	Homo sapiens (human)
detection of UV	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to lead ion	Ferrochelatase, mitochondrial	Homo sapiens (human)
regulation of eIF2 alpha phosphorylation by heme	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to insecticide	Ferrochelatase, mitochondrial	Homo sapiens (human)
erythrocyte differentiation	Ferrochelatase, mitochondrial	Homo sapiens (human)
very-low-density lipoprotein particle assembly	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to ethanol	Ferrochelatase, mitochondrial	Homo sapiens (human)
protoporphyrinogen IX metabolic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to arsenic-containing substance	Ferrochelatase, mitochondrial	Homo sapiens (human)
regulation of hemoglobin biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme O biosynthetic process	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to methylmercury	Ferrochelatase, mitochondrial	Homo sapiens (human)
multicellular organismal-level iron ion homeostasis	Ferrochelatase, mitochondrial	Homo sapiens (human)
response to platinum ion	Ferrochelatase, mitochondrial	Homo sapiens (human)
cellular response to dexamethasone stimulus	Ferrochelatase, mitochondrial	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
behavioral fear response	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
skeletal muscle contraction	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
apoptotic process	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
signal transduction	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
germ cell development	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
long-term memory	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to xenobiotic stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to mechanical stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to toxic substance	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to glucose	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
skeletal muscle atrophy	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to electrical stimulus involved in regulation of muscle adaptation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of smooth muscle cell migration	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cell migration	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to nutrient levels	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to nutrient	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
TOR signaling	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to lipopolysaccharide	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to testosterone	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to glucagon	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to tumor necrosis factor	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
negative regulation of apoptotic process	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to L-leucine	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
long-chain fatty acid import into cell	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to ethanol	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of translation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of mitotic cell cycle	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of translational initiation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
regulation of glucose import	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
phosphatidylinositol-mediated signaling	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of skeletal muscle tissue growth	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
modulation of chemical synaptic transmission	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to type II interferon	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to growth factor stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to dexamethasone stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
positive regulation of TORC1 signaling	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cellular response to insulin stimulus	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
response to antibiotic	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
positive regulation of homotypic cell-cell adhesion	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-15-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-4-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-2-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-9-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-11-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
type III interferon-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
type II interferon-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
type I interferon-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-6-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
T-helper 17 cell lineage commitment	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cellular response to virus	Tyrosine-protein kinase JAK1	Homo sapiens (human)
interleukin-10-mediated signaling pathway	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein localization to cell-cell junction	Tyrosine-protein kinase JAK1	Homo sapiens (human)
positive regulation of protein localization to nucleus	Tyrosine-protein kinase JAK1	Homo sapiens (human)
positive regulation of sprouting angiogenesis	Tyrosine-protein kinase JAK1	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase JAK1	Homo sapiens (human)
tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase JAK1	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase JAK1	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 2	Homo sapiens (human)
DNA replication	Cyclin-dependent kinase 2	Homo sapiens (human)
DNA repair	Cyclin-dependent kinase 2	Homo sapiens (human)
chromatin remodeling	Cyclin-dependent kinase 2	Homo sapiens (human)
DNA-templated transcription	Cyclin-dependent kinase 2	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 2	Homo sapiens (human)
potassium ion transport	Cyclin-dependent kinase 2	Homo sapiens (human)
centriole replication	Cyclin-dependent kinase 2	Homo sapiens (human)
Ras protein signal transduction	Cyclin-dependent kinase 2	Homo sapiens (human)
regulation of mitotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of cell population proliferation	Cyclin-dependent kinase 2	Homo sapiens (human)
peptidyl-serine phosphorylation	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of heterochromatin formation	Cyclin-dependent kinase 2	Homo sapiens (human)
mitotic G1 DNA damage checkpoint signaling	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of DNA-templated DNA replication initiation	Cyclin-dependent kinase 2	Homo sapiens (human)
telomere maintenance in response to DNA damage	Cyclin-dependent kinase 2	Homo sapiens (human)
post-translational protein modification	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of DNA replication	Cyclin-dependent kinase 2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Cyclin-dependent kinase 2	Homo sapiens (human)
centrosome duplication	Cyclin-dependent kinase 2	Homo sapiens (human)
cell division	Cyclin-dependent kinase 2	Homo sapiens (human)
meiotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
cellular response to nitric oxide	Cyclin-dependent kinase 2	Homo sapiens (human)
cellular senescence	Cyclin-dependent kinase 2	Homo sapiens (human)
regulation of anaphase-promoting complex-dependent catabolic process	Cyclin-dependent kinase 2	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 2	Homo sapiens (human)
signal transduction	Cyclin-dependent kinase 2	Homo sapiens (human)
regulation of gene expression	Cyclin-dependent kinase 2	Homo sapiens (human)
response to organic substance	Cyclin-dependent kinase 2	Homo sapiens (human)
desensitization of G protein-coupled receptor signaling pathway	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
negative regulation of the force of heart contraction by chemical signal	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
G protein-coupled acetylcholine receptor signaling pathway	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
tachykinin receptor signaling pathway	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
heart development	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
viral genome replication	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
receptor internalization	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
positive regulation of catecholamine secretion	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
negative regulation of striated muscle contraction	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
symbiont entry into host cell	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
cardiac muscle contraction	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
negative regulation of relaxation of smooth muscle	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
regulation of the force of heart contraction	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
protein phosphorylation	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
P-body assembly	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
miRNA-mediated gene silencing by inhibition of translation	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
negative regulation of translation	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
viral RNA genome packaging	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
stem cell population maintenance	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
neuron differentiation	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
P-body assembly	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
negative regulation of neuron differentiation	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
stress granule assembly	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
positive regulation of macrophage chemotaxis	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of macrophage proliferation	Mitogen-activated protein kinase 3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
DNA-templated transcription	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 3	Homo sapiens (human)
apoptotic process	Mitogen-activated protein kinase 3	Homo sapiens (human)
insulin receptor signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
Schwann cell development	Mitogen-activated protein kinase 3	Homo sapiens (human)
phosphorylation	Mitogen-activated protein kinase 3	Homo sapiens (human)
sensory perception of pain	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of ossification	Mitogen-activated protein kinase 3	Homo sapiens (human)
BMP signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of cellular pH	Mitogen-activated protein kinase 3	Homo sapiens (human)
thyroid gland development	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of cyclase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of stress-activated MAPK cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to amino acid starvation	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to reactive oxygen species	Mitogen-activated protein kinase 3	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Mitogen-activated protein kinase 3	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
outer ear morphogenesis	Mitogen-activated protein kinase 3	Homo sapiens (human)
myelination	Mitogen-activated protein kinase 3	Homo sapiens (human)
signal transduction in response to DNA damage	Mitogen-activated protein kinase 3	Homo sapiens (human)
response to exogenous dsRNA	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 3	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
thymus development	Mitogen-activated protein kinase 3	Homo sapiens (human)
modulation of chemical synaptic transmission	Mitogen-activated protein kinase 3	Homo sapiens (human)
cartilage development	Mitogen-activated protein kinase 3	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of cytoskeleton organization	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of telomerase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
Bergmann glial cell differentiation	Mitogen-activated protein kinase 3	Homo sapiens (human)
face development	Mitogen-activated protein kinase 3	Homo sapiens (human)
lung morphogenesis	Mitogen-activated protein kinase 3	Homo sapiens (human)
trachea formation	Mitogen-activated protein kinase 3	Homo sapiens (human)
cardiac neural crest cell development involved in heart development	Mitogen-activated protein kinase 3	Homo sapiens (human)
ERK1 and ERK2 cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Mitogen-activated protein kinase 3	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Mitogen-activated protein kinase 3	Homo sapiens (human)
response to epidermal growth factor	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to mechanical stimulus	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to cadmium ion	Mitogen-activated protein kinase 3	Homo sapiens (human)
cellular response to tumor necrosis factor	Mitogen-activated protein kinase 3	Homo sapiens (human)
caveolin-mediated endocytosis	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of Golgi inheritance	Mitogen-activated protein kinase 3	Homo sapiens (human)
xenophagy	Mitogen-activated protein kinase 3	Homo sapiens (human)
negative regulation of TORC1 signaling	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of telomere capping	Mitogen-activated protein kinase 3	Homo sapiens (human)
positive regulation of xenophagy	Mitogen-activated protein kinase 3	Homo sapiens (human)
regulation of early endosome to late endosome transport	Mitogen-activated protein kinase 3	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein phosphorylation	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
peptidyl-serine phosphorylation	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
positive regulation of protein binding	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
negative regulation of hippo signaling	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
peptidyl-serine autophosphorylation	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
negative regulation of protein localization to nucleus	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
intracellular signal transduction	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
pyrimidine nucleotide metabolic process	Deoxycytidine kinase	Homo sapiens (human)
CMP biosynthetic process	Deoxycytidine kinase	Homo sapiens (human)
dAMP salvage	Deoxycytidine kinase	Homo sapiens (human)
nucleoside phosphate biosynthetic process	Deoxycytidine kinase	Homo sapiens (human)
positive regulation of macrophage chemotaxis	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of macrophage proliferation	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 1	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 1	Homo sapiens (human)
apoptotic process	Mitogen-activated protein kinase 1	Homo sapiens (human)
chemotaxis	Mitogen-activated protein kinase 1	Homo sapiens (human)
DNA damage response	Mitogen-activated protein kinase 1	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 1	Homo sapiens (human)
chemical synaptic transmission	Mitogen-activated protein kinase 1	Homo sapiens (human)
learning or memory	Mitogen-activated protein kinase 1	Homo sapiens (human)
insulin receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	Mitogen-activated protein kinase 1	Homo sapiens (human)
Schwann cell development	Mitogen-activated protein kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase 1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytosine metabolic process	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of ossification	Mitogen-activated protein kinase 1	Homo sapiens (human)
androgen receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of cellular pH	Mitogen-activated protein kinase 1	Homo sapiens (human)
thyroid gland development	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of protein stability	Mitogen-activated protein kinase 1	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of stress-activated MAPK cascade	Mitogen-activated protein kinase 1	Homo sapiens (human)
mammary gland epithelial cell proliferation	Mitogen-activated protein kinase 1	Homo sapiens (human)
cellular response to amino acid starvation	Mitogen-activated protein kinase 1	Homo sapiens (human)
cellular response to reactive oxygen species	Mitogen-activated protein kinase 1	Homo sapiens (human)
response to nicotine	Mitogen-activated protein kinase 1	Homo sapiens (human)
ERBB signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
outer ear morphogenesis	Mitogen-activated protein kinase 1	Homo sapiens (human)
myelination	Mitogen-activated protein kinase 1	Homo sapiens (human)
response to exogenous dsRNA	Mitogen-activated protein kinase 1	Homo sapiens (human)
steroid hormone mediated signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
negative regulation of cell differentiation	Mitogen-activated protein kinase 1	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
thymus development	Mitogen-activated protein kinase 1	Homo sapiens (human)
progesterone receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
T cell receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
B cell receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of cytoskeleton organization	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of telomerase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
Bergmann glial cell differentiation	Mitogen-activated protein kinase 1	Homo sapiens (human)
long-term synaptic potentiation	Mitogen-activated protein kinase 1	Homo sapiens (human)
face development	Mitogen-activated protein kinase 1	Homo sapiens (human)
lung morphogenesis	Mitogen-activated protein kinase 1	Homo sapiens (human)
trachea formation	Mitogen-activated protein kinase 1	Homo sapiens (human)
labyrinthine layer blood vessel development	Mitogen-activated protein kinase 1	Homo sapiens (human)
cardiac neural crest cell development involved in heart development	Mitogen-activated protein kinase 1	Homo sapiens (human)
ERK1 and ERK2 cascade	Mitogen-activated protein kinase 1	Homo sapiens (human)
response to epidermal growth factor	Mitogen-activated protein kinase 1	Homo sapiens (human)
cellular response to cadmium ion	Mitogen-activated protein kinase 1	Homo sapiens (human)
cellular response to tumor necrosis factor	Mitogen-activated protein kinase 1	Homo sapiens (human)
caveolin-mediated endocytosis	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of Golgi inheritance	Mitogen-activated protein kinase 1	Homo sapiens (human)
positive regulation of telomere capping	Mitogen-activated protein kinase 1	Homo sapiens (human)
regulation of early endosome to late endosome transport	Mitogen-activated protein kinase 1	Homo sapiens (human)
cell surface receptor signaling pathway	Mitogen-activated protein kinase 1	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 1	Homo sapiens (human)
skeletal system development	Ephrin type-A receptor 2	Homo sapiens (human)
vasculogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
osteoblast differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
inflammatory response	Ephrin type-A receptor 2	Homo sapiens (human)
cell adhesion	Ephrin type-A receptor 2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of lamellipodium assembly	Ephrin type-A receptor 2	Homo sapiens (human)
notochord formation	Ephrin type-A receptor 2	Homo sapiens (human)
cell migration	Ephrin type-A receptor 2	Homo sapiens (human)
negative regulation of angiogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
neural tube development	Ephrin type-A receptor 2	Homo sapiens (human)
neuron differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
keratinocyte differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
osteoclast differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
positive regulation of cell migration	Ephrin type-A receptor 2	Homo sapiens (human)
negative regulation of chemokine production	Ephrin type-A receptor 2	Homo sapiens (human)
mammary gland epithelial cell proliferation	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of cell adhesion mediated by integrin	Ephrin type-A receptor 2	Homo sapiens (human)
post-anal tail morphogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of blood vessel endothelial cell migration	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of angiogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
cAMP metabolic process	Ephrin type-A receptor 2	Homo sapiens (human)
symbiont entry into host cell	Ephrin type-A receptor 2	Homo sapiens (human)
bone remodeling	Ephrin type-A receptor 2	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 2	Homo sapiens (human)
axial mesoderm formation	Ephrin type-A receptor 2	Homo sapiens (human)
cell motility	Ephrin type-A receptor 2	Homo sapiens (human)
defense response to Gram-positive bacterium	Ephrin type-A receptor 2	Homo sapiens (human)
notochord cell development	Ephrin type-A receptor 2	Homo sapiens (human)
cell chemotaxis	Ephrin type-A receptor 2	Homo sapiens (human)
branching involved in mammary gland duct morphogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
lens fiber cell morphogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Ephrin type-A receptor 2	Homo sapiens (human)
response to growth factor	Ephrin type-A receptor 2	Homo sapiens (human)
protein localization to plasma membrane	Ephrin type-A receptor 2	Homo sapiens (human)
activation of GTPase activity	Ephrin type-A receptor 2	Homo sapiens (human)
negative regulation of lymphangiogenesis	Ephrin type-A receptor 2	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Ephrin type-A receptor 2	Homo sapiens (human)
positive regulation of bicellular tight junction assembly	Ephrin type-A receptor 2	Homo sapiens (human)
pericyte cell differentiation	Ephrin type-A receptor 2	Homo sapiens (human)
positive regulation of kinase activity	Ephrin type-A receptor 2	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Ephrin type-A receptor 2	Homo sapiens (human)
multicellular organism development	Ephrin type-A receptor 2	Homo sapiens (human)
negative regulation of protein kinase activity	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of autophagosome assembly	Ephrin type-B receptor 2	Homo sapiens (human)
angiogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
urogenital system development	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of protein phosphorylation	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of immunoglobulin production	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of cell adhesion	Ephrin type-B receptor 2	Homo sapiens (human)
nervous system development	Ephrin type-B receptor 2	Homo sapiens (human)
axon guidance	Ephrin type-B receptor 2	Homo sapiens (human)
axonal fasciculation	Ephrin type-B receptor 2	Homo sapiens (human)
learning or memory	Ephrin type-B receptor 2	Homo sapiens (human)
learning	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of gene expression	Ephrin type-B receptor 2	Homo sapiens (human)
phosphorylation	Ephrin type-B receptor 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Ephrin type-B receptor 2	Homo sapiens (human)
optic nerve morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
hindbrain tangential cell migration	Ephrin type-B receptor 2	Homo sapiens (human)
central nervous system projection neuron axonogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
corpus callosum development	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of blood coagulation	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of cell migration	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of B cell proliferation	Ephrin type-B receptor 2	Homo sapiens (human)
retinal ganglion cell axon guidance	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of synaptic plasticity	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Ephrin type-B receptor 2	Homo sapiens (human)
B cell activation	Ephrin type-B receptor 2	Homo sapiens (human)
inner ear morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of receptor signaling pathway via JAK-STAT	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of Ras protein signal transduction	Ephrin type-B receptor 2	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of neuronal synaptic plasticity	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of long-term neuronal synaptic plasticity	Ephrin type-B receptor 2	Homo sapiens (human)
camera-type eye morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of axonogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of body fluid levels	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of filopodium assembly	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of synapse assembly	Ephrin type-B receptor 2	Homo sapiens (human)
roof of mouth development	Ephrin type-B receptor 2	Homo sapiens (human)
dendritic spine development	Ephrin type-B receptor 2	Homo sapiens (human)
dendritic spine morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of dendritic spine morphogenesis	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Ephrin type-B receptor 2	Homo sapiens (human)
cellular response to lipopolysaccharide	Ephrin type-B receptor 2	Homo sapiens (human)
commissural neuron axon guidance	Ephrin type-B receptor 2	Homo sapiens (human)
postsynaptic membrane assembly	Ephrin type-B receptor 2	Homo sapiens (human)
trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission	Ephrin type-B receptor 2	Homo sapiens (human)
neuron projection retraction	Ephrin type-B receptor 2	Homo sapiens (human)
vesicle-mediated intercellular transport	Ephrin type-B receptor 2	Homo sapiens (human)
tight junction assembly	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of cytokine production involved in inflammatory response	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of long-term synaptic potentiation	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Ephrin type-B receptor 2	Homo sapiens (human)
cellular response to amyloid-beta	Ephrin type-B receptor 2	Homo sapiens (human)
negative regulation of NMDA glutamate receptor activity	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of NMDA glutamate receptor activity	Ephrin type-B receptor 2	Homo sapiens (human)
positive regulation of protein localization to cell surface	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of T-helper 17 type immune response	Ephrin type-B receptor 2	Homo sapiens (human)
regulation of behavioral fear response	Ephrin type-B receptor 2	Homo sapiens (human)
protein phosphorylation	Ephrin type-B receptor 2	Homo sapiens (human)
protein phosphorylation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
immune response	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytokine-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of type II interferon production	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of interleukin-17 production	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of natural killer cell proliferation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
interleukin-12-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
type III interferon-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of T cell proliferation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of NK T cell proliferation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
type II interferon-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
type I interferon-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cellular response to virus	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
interleukin-10-mediated signaling pathway	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of protein localization to nucleus	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
positive regulation of T-helper 17 type immune response	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
intracellular signal transduction	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cell differentiation	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
'de novo' pyrimidine nucleobase biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
UMP biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
UDP biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
pyrimidine ribonucleotide biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
nucleobase-containing small molecule interconversion	UMP-CMP kinase	Homo sapiens (human)
nucleoside monophosphate phosphorylation	UMP-CMP kinase	Homo sapiens (human)
CDP biosynthetic process	UMP-CMP kinase	Homo sapiens (human)
negative regulation of MAPK cascade	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Wee1-like protein kinase	Homo sapiens (human)
microtubule cytoskeleton organization	Wee1-like protein kinase	Homo sapiens (human)
negative regulation of G2/M transition of mitotic cell cycle	Wee1-like protein kinase	Homo sapiens (human)
establishment of cell polarity	Wee1-like protein kinase	Homo sapiens (human)
positive regulation of DNA replication	Wee1-like protein kinase	Homo sapiens (human)
neuron projection morphogenesis	Wee1-like protein kinase	Homo sapiens (human)
cell division	Wee1-like protein kinase	Homo sapiens (human)
negative regulation of G1/S transition of mitotic cell cycle	Wee1-like protein kinase	Homo sapiens (human)
protein phosphorylation	Wee1-like protein kinase	Homo sapiens (human)
response to hypoxia	Heme oxygenase 2	Homo sapiens (human)
response to oxidative stress	Heme oxygenase 2	Homo sapiens (human)
heme catabolic process	Heme oxygenase 2	Homo sapiens (human)
heme oxidation	Heme oxygenase 2	Homo sapiens (human)
neuron migration	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of cytokine-mediated signaling pathway	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
blood vessel remodeling	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
phagocytosis	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
inflammatory response	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
spermatogenesis	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of macrophage cytokine production	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
forebrain cell migration	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
animal organ regeneration	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of type II interferon production	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of tumor necrosis factor production	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of natural killer cell differentiation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
secretion by cell	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
erythrocyte homeostasis	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cellular response to interferon-alpha	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
ovulation cycle	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of neuron apoptotic process	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
symbiont entry into host cell	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cell maturation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of pinocytosis	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
response to axon injury	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of lymphocyte activation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
neuron apoptotic process	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
establishment of localization in cell	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
vagina development	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cellular response to hydrogen peroxide	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cellular response to lipopolysaccharide	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
dendritic cell differentiation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
neutrophil clearance	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of viral life cycle	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of dendritic cell apoptotic process	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
platelet activation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
natural killer cell differentiation	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cell migration	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
positive regulation of kinase activity	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
nervous system development	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
multicellular organism development	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
negative regulation of apoptotic process	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
S-adenosylmethionine biosynthetic process	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
one-carbon metabolic process	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
protein hexamerization	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
protein heterooligomerization	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
cellular response to methionine	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
positive regulation of TORC1 signaling	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
cellular response to leukemia inhibitory factor	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
protein folding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
response to unfolded protein	DnaJ homolog subfamily A member 1	Homo sapiens (human)
spermatogenesis	DnaJ homolog subfamily A member 1	Homo sapiens (human)
response to heat	DnaJ homolog subfamily A member 1	Homo sapiens (human)
flagellated sperm motility	DnaJ homolog subfamily A member 1	Homo sapiens (human)
androgen receptor signaling pathway	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of protein ubiquitination	DnaJ homolog subfamily A member 1	Homo sapiens (human)
positive regulation of apoptotic process	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of apoptotic process	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of JUN kinase activity	DnaJ homolog subfamily A member 1	Homo sapiens (human)
regulation of protein transport	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein localization to mitochondrion	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of establishment of protein localization to mitochondrion	DnaJ homolog subfamily A member 1	Homo sapiens (human)
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein refolding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
activation-induced cell death of T cells	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
intracellular signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
osteoblast differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
maternal placenta development	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of endothelial cell proliferation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell migration involved in sprouting angiogenesis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
sphingosine-1-phosphate receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glycogen biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of glycogen biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glucose metabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of translation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein import into nucleus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nitric oxide biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
inflammatory response	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to oxidative stress	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
G protein-coupled receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
canonical NF-kappaB signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell population proliferation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
insulin receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
apoptotic mitochondrial changes	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to heat	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
gene expression	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of autophagy	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of endothelial cell migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of gene expression	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of gene expression	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of long-chain fatty acid import across plasma membrane	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
fibroblast migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of fibroblast migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of sodium ion transport	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glucose metabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of endopeptidase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of neuron projection development	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of macroautophagy	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein ubiquitination	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
peptidyl-threonine phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
virus-mediated perturbation of host defense response	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cytokine-mediated signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
mammalian oogenesis stage	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell growth	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
T cell costimulation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein ubiquitination	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of myelination	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
TOR signaling	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of fatty acid beta-oxidation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of endodeoxyribonuclease activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to food	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
peripheral nervous system myelin maintenance	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to insulin stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to fluid shear stress	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to reactive oxygen species	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
interleukin-18-mediated signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to decreased oxygen levels	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
non-canonical NF-kappaB signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glucose homeostasis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of apoptotic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of apoptotic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
anoikis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of mRNA stability	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of fat cell differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glycogen biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cyclin-dependent protein serine/threonine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of Notch signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of proteolysis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of DNA-templated transcription	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glucose import	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of organ growth	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein autophosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of lipid biosynthetic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
behavioral response to pain	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of nitric-oxide synthase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
striated muscle cell differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein metabolic process	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
excitatory postsynaptic potential	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to growth hormone	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
mammary gland epithelial cell differentiation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
labyrinthine layer blood vessel development	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to UV-A	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to growth factor	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to cadmium ion	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to tumor necrosis factor	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to epidermal growth factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to prostaglandin E stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein serine/threonine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
establishment of protein localization to mitochondrion	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
maintenance of protein location in mitochondrion	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of release of cytochrome c from mitochondria	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to granulocyte macrophage colony-stimulating factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
execution phase of apoptosis	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of postsynapse organization	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of tRNA methylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to oxidised low-density lipoprotein particle stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of protein localization to lysosome	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cGAS/STING signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of G1/S transition of mitotic cell cycle	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein localization to nucleus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to peptide	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cilium assembly	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of leukocyte cell-cell adhesion	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of I-kappaB phosphorylation	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of TORC1 signaling	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein localization to endoplasmic reticulum	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cellular response to nerve growth factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
response to insulin-like growth factor stimulus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein localization to cell surface	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
regulation of type B pancreatic cell development	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of lymphocyte migration	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
intracellular signal transduction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glycogen biosynthetic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
glucose metabolic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
regulation of translation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
signal transduction	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
insulin receptor signaling pathway	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of long-chain fatty acid import across plasma membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glucose metabolic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell migration	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell migration	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of fatty acid beta-oxidation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
peripheral nervous system myelin maintenance	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
cellular response to insulin stimulus	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
protein modification process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
fat cell differentiation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glycogen biosynthetic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of glucose import	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell cycle	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
mammary gland epithelial cell differentiation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
cellular response to high light intensity	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
organic substance transport	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
protein localization to plasma membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of protein targeting to membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
retinal rod cell apoptotic process	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell motility	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
intracellular signal transduction	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
microtubule-based movement	Kinesin-1 heavy chain	Homo sapiens (human)
cytoplasm organization	Kinesin-1 heavy chain	Homo sapiens (human)
positive regulation of synaptic transmission, GABAergic	Kinesin-1 heavy chain	Homo sapiens (human)
lysosome localization	Kinesin-1 heavy chain	Homo sapiens (human)
stress granule disassembly	Kinesin-1 heavy chain	Homo sapiens (human)
natural killer cell mediated cytotoxicity	Kinesin-1 heavy chain	Homo sapiens (human)
regulation of membrane potential	Kinesin-1 heavy chain	Homo sapiens (human)
positive regulation of potassium ion transport	Kinesin-1 heavy chain	Homo sapiens (human)
vesicle transport along microtubule	Kinesin-1 heavy chain	Homo sapiens (human)
mitochondrion transport along microtubule	Kinesin-1 heavy chain	Homo sapiens (human)
centrosome localization	Kinesin-1 heavy chain	Homo sapiens (human)
cellular response to type II interferon	Kinesin-1 heavy chain	Homo sapiens (human)
plus-end-directed vesicle transport along microtubule	Kinesin-1 heavy chain	Homo sapiens (human)
anterograde axonal protein transport	Kinesin-1 heavy chain	Homo sapiens (human)
mitocytosis	Kinesin-1 heavy chain	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Kinesin-1 heavy chain	Homo sapiens (human)
anterograde neuronal dense core vesicle transport	Kinesin-1 heavy chain	Homo sapiens (human)
retrograde neuronal dense core vesicle transport	Kinesin-1 heavy chain	Homo sapiens (human)
axon guidance	Kinesin-1 heavy chain	Homo sapiens (human)
synaptic vesicle transport	Kinesin-1 heavy chain	Homo sapiens (human)
anterograde dendritic transport of neurotransmitter receptor complex	Kinesin-1 heavy chain	Homo sapiens (human)
spindle organization	Dual specificity protein kinase TTK	Homo sapiens (human)
mitotic spindle organization	Dual specificity protein kinase TTK	Homo sapiens (human)
positive regulation of cell population proliferation	Dual specificity protein kinase TTK	Homo sapiens (human)
female meiosis chromosome segregation	Dual specificity protein kinase TTK	Homo sapiens (human)
protein localization to meiotic spindle midzone	Dual specificity protein kinase TTK	Homo sapiens (human)
chromosome segregation	Dual specificity protein kinase TTK	Homo sapiens (human)
peptidyl-serine phosphorylation	Dual specificity protein kinase TTK	Homo sapiens (human)
protein localization to kinetochore	Dual specificity protein kinase TTK	Homo sapiens (human)
mitotic spindle assembly checkpoint signaling	Dual specificity protein kinase TTK	Homo sapiens (human)
meiotic spindle assembly checkpoint signaling	Dual specificity protein kinase TTK	Homo sapiens (human)
DNA replication	DNA replication licensing factor MCM4	Homo sapiens (human)
DNA unwinding involved in DNA replication	DNA replication licensing factor MCM4	Homo sapiens (human)
regulation of DNA-templated DNA replication initiation	DNA replication licensing factor MCM4	Homo sapiens (human)
double-strand break repair via break-induced replication	DNA replication licensing factor MCM4	Homo sapiens (human)
DNA strand elongation involved in DNA replication	DNA replication licensing factor MCM4	Homo sapiens (human)
mitotic DNA replication initiation	DNA replication licensing factor MCM4	Homo sapiens (human)
mitotic cytokinesis	Myosin-10	Homo sapiens (human)
actin filament-based movement	Myosin-10	Homo sapiens (human)
cell adhesion	Myosin-10	Homo sapiens (human)
actomyosin structure organization	Myosin-10	Homo sapiens (human)
positive regulation of protein secretion	Myosin-10	Homo sapiens (human)
mitotic cytokinesis	Myosin-10	Homo sapiens (human)
regulation of cell shape	Myosin-10	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of protein phosphorylation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
vasculature development	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
lymph vessel development	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
lymphangiogenesis	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
sprouting angiogenesis	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
respiratory system process	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of cell population proliferation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of vascular endothelial growth factor production	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of endothelial cell migration	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
negative regulation of apoptotic process	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of MAPK cascade	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of JNK cascade	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein autophosphorylation	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
lung alveolus development	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
blood vessel morphogenesis	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
regulation of blood vessel remodeling	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of protein kinase C signaling	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of cell migration	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
positive regulation of kinase activity	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
multicellular organism development	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
regulation of MAPK cascade	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
angiogenesis	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
branching involved in blood vessel morphogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of macroautophagy	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of mitochondrial depolarization	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of mitochondrial fission	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
ovarian follicle development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vasculogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of protein phosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
lymph vessel development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell migration involved in sprouting angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
epithelial cell maturation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endocardium development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endothelium development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of cell population proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of cell shape	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
mesenchymal cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of endothelial cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
negative regulation of gene expression	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of BMP signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
embryonic hemopoiesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor receptor-2 signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
surfactant homeostasis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of MAPK cascade	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
negative regulation of neuron apoptotic process	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell fate commitment	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
protein autophosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
lung alveolus development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
post-embryonic camera-type eye morphogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
epithelial cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of positive chemotaxis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of focal adhesion assembly	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
calcium ion homeostasis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
blood vessel endothelial cell differentiation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular wound healing	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
semaphorin-plexin signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
stem cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of hematopoietic progenitor cell differentiation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of bone development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cellular response to hydrogen sulfide	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of stem cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of vasculogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of MAPK cascade	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
multicellular organism development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endothelial cell differentiation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of kinase activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
heart development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of gene expression	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
Schwann cell development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
thyroid gland development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
regulation of stress-activated MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
peptidyl-serine autophosphorylation	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
myelination	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
thymus development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
regulation of axon regeneration	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of axonogenesis	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
face development	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
trachea formation	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
epithelial cell proliferation involved in lung morphogenesis	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
ERK1 and ERK2 cascade	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
regulation of Golgi inheritance	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
positive regulation of cell motility	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
regulation of early endosome to late endosome transport	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
hemopoiesis	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
leukocyte homeostasis	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
myeloid progenitor cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
pro-B cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of cell population proliferation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
response to organonitrogen compound	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cytokine-mediated signaling pathway	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
B cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
animal organ regeneration	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
common myeloid progenitor cell proliferation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
regulation of apoptotic process	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of MAP kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of MAPK cascade	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
lymphocyte proliferation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein autophosphorylation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cellular response to cytokine stimulus	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cellular response to glucocorticoid stimulus	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
dendritic cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
multicellular organism development	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
regulation of cardiac muscle cell apoptotic process	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
regulation of neural crest cell differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of gene expression	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
negative regulation of gene expression	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of transforming growth factor beta2 production	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
angiogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
osteoblast differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
in utero embryonic development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
mesoderm formation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
somitogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
Mullerian duct regression	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
chondrocyte differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
outflow tract septum morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
outflow tract morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cardiac conduction system development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
atrioventricular valve development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
mitral valve morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
tricuspid valve morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
endocardial cushion morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cardiac right ventricle morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ventricular trabecula myocardium morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ventricular compact myocardium morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
endocardial cushion formation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
immune response	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ectoderm development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
dorsal/ventral axis specification	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
neural crest cell development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
negative regulation of smooth muscle cell migration	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
central nervous system neuron differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
pituitary gland development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
neural plate mediolateral regionalization	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
lung development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of bone mineralization	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
BMP signaling pathway	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
somatic stem cell population maintenance	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
hindlimb morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
dorsal aorta morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
odontogenesis of dentin-containing tooth	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
embryonic digit morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of osteoblast differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
paraxial mesoderm structural organization	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
lateral mesoderm development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
regulation of lateral mesodermal cell fate specification	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
mesendoderm development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
embryonic organ development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
developmental growth	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
epithelial cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of epithelial cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
negative regulation of neurogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
negative regulation of muscle cell differentiation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
roof of mouth development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
regulation of cardiac muscle cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ventricular septum morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
heart formation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
atrioventricular node cell development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
pharyngeal arch artery morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cellular response to BMP stimulus	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of miRNA transcription	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of cardiac ventricle development	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
fibrous ring of heart morphogenesis	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
regulation of cellular senescence	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
protein phosphorylation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
dorsal/ventral pattern formation	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cellular response to growth factor stimulus	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Activin receptor type-1B	Homo sapiens (human)
in utero embryonic development	Activin receptor type-1B	Homo sapiens (human)
hair follicle development	Activin receptor type-1B	Homo sapiens (human)
regulation of DNA-templated transcription	Activin receptor type-1B	Homo sapiens (human)
signal transduction	Activin receptor type-1B	Homo sapiens (human)
cell surface receptor protein serine/threonine kinase signaling pathway	Activin receptor type-1B	Homo sapiens (human)
positive regulation of gene expression	Activin receptor type-1B	Homo sapiens (human)
negative regulation of gene expression	Activin receptor type-1B	Homo sapiens (human)
peptidyl-threonine phosphorylation	Activin receptor type-1B	Homo sapiens (human)
negative regulation of cell growth	Activin receptor type-1B	Homo sapiens (human)
activin receptor signaling pathway	Activin receptor type-1B	Homo sapiens (human)
positive regulation of activin receptor signaling pathway	Activin receptor type-1B	Homo sapiens (human)
nodal signaling pathway	Activin receptor type-1B	Homo sapiens (human)
positive regulation of erythrocyte differentiation	Activin receptor type-1B	Homo sapiens (human)
protein autophosphorylation	Activin receptor type-1B	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Activin receptor type-1B	Homo sapiens (human)
positive regulation of trophoblast cell migration	Activin receptor type-1B	Homo sapiens (human)
cellular response to growth factor stimulus	Activin receptor type-1B	Homo sapiens (human)
protein phosphorylation	Activin receptor type-1B	Homo sapiens (human)
nervous system development	Activin receptor type-1B	Homo sapiens (human)
proepicardium development	TGF-beta receptor type-1	Homo sapiens (human)
negative regulation of cell migration	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of extracellular matrix assembly	TGF-beta receptor type-1	Homo sapiens (human)
skeletal system development	TGF-beta receptor type-1	Homo sapiens (human)
in utero embryonic development	TGF-beta receptor type-1	Homo sapiens (human)
kidney development	TGF-beta receptor type-1	Homo sapiens (human)
blastocyst development	TGF-beta receptor type-1	Homo sapiens (human)
epithelial to mesenchymal transition	TGF-beta receptor type-1	Homo sapiens (human)
endothelial cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
negative regulation of endothelial cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of endothelial cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
lens development in camera-type eye	TGF-beta receptor type-1	Homo sapiens (human)
ventricular trabecula myocardium morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
ventricular compact myocardium morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
regulation of DNA-templated transcription	TGF-beta receptor type-1	Homo sapiens (human)
apoptotic process	TGF-beta receptor type-1	Homo sapiens (human)
signal transduction	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	TGF-beta receptor type-1	Homo sapiens (human)
heart development	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of cell population proliferation	TGF-beta receptor type-1	Homo sapiens (human)
germ cell migration	TGF-beta receptor type-1	Homo sapiens (human)
male gonad development	TGF-beta receptor type-1	Homo sapiens (human)
post-embryonic development	TGF-beta receptor type-1	Homo sapiens (human)
anterior/posterior pattern specification	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of gene expression	TGF-beta receptor type-1	Homo sapiens (human)
regulation of epithelial to mesenchymal transition	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition	TGF-beta receptor type-1	Homo sapiens (human)
peptidyl-serine phosphorylation	TGF-beta receptor type-1	Homo sapiens (human)
collagen fibril organization	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of cell growth	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of cell migration	TGF-beta receptor type-1	Homo sapiens (human)
regulation of protein ubiquitination	TGF-beta receptor type-1	Homo sapiens (human)
negative regulation of chondrocyte differentiation	TGF-beta receptor type-1	Homo sapiens (human)
activin receptor signaling pathway	TGF-beta receptor type-1	Homo sapiens (human)
intracellular signal transduction	TGF-beta receptor type-1	Homo sapiens (human)
myofibroblast differentiation	TGF-beta receptor type-1	Homo sapiens (human)
wound healing	TGF-beta receptor type-1	Homo sapiens (human)
endothelial cell activation	TGF-beta receptor type-1	Homo sapiens (human)
extracellular structure organization	TGF-beta receptor type-1	Homo sapiens (human)
endothelial cell migration	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	TGF-beta receptor type-1	Homo sapiens (human)
filopodium assembly	TGF-beta receptor type-1	Homo sapiens (human)
thymus development	TGF-beta receptor type-1	Homo sapiens (human)
neuron fate commitment	TGF-beta receptor type-1	Homo sapiens (human)
embryonic cranial skeleton morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
skeletal system morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
mesenchymal cell differentiation	TGF-beta receptor type-1	Homo sapiens (human)
artery morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
cell motility	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of filopodium assembly	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of stress fiber assembly	TGF-beta receptor type-1	Homo sapiens (human)
regulation of cell cycle	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	TGF-beta receptor type-1	Homo sapiens (human)
parathyroid gland development	TGF-beta receptor type-1	Homo sapiens (human)
roof of mouth development	TGF-beta receptor type-1	Homo sapiens (human)
pharyngeal system development	TGF-beta receptor type-1	Homo sapiens (human)
regulation of cardiac muscle cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
cardiac epithelial to mesenchymal transition	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	TGF-beta receptor type-1	Homo sapiens (human)
ventricular septum morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
angiogenesis involved in coronary vascular morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
coronary artery morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
response to cholesterol	TGF-beta receptor type-1	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of mesenchymal stem cell proliferation	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of vasculature development	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of tight junction disassembly	TGF-beta receptor type-1	Homo sapiens (human)
epicardium morphogenesis	TGF-beta receptor type-1	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	TGF-beta receptor type-1	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	TGF-beta receptor type-1	Homo sapiens (human)
protein phosphorylation	TGF-beta receptor type-1	Homo sapiens (human)
cellular response to growth factor stimulus	TGF-beta receptor type-1	Homo sapiens (human)
nervous system development	TGF-beta receptor type-1	Homo sapiens (human)
cell proliferation involved in endocardial cushion morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
superior endocardial cushion morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
blood vessel development	TGF-beta receptor type-2	Homo sapiens (human)
branching involved in blood vessel morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
vasculogenesis	TGF-beta receptor type-2	Homo sapiens (human)
in utero embryonic development	TGF-beta receptor type-2	Homo sapiens (human)
epithelial to mesenchymal transition	TGF-beta receptor type-2	Homo sapiens (human)
heart looping	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	TGF-beta receptor type-2	Homo sapiens (human)
lens development in camera-type eye	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of tolerance induction to self antigen	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of B cell tolerance induction	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of T cell tolerance induction	TGF-beta receptor type-2	Homo sapiens (human)
outflow tract septum morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
membranous septum morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
outflow tract morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
aortic valve morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
atrioventricular valve morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
tricuspid valve morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
cardiac left ventricle morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
endocardial cushion fusion	TGF-beta receptor type-2	Homo sapiens (human)
growth plate cartilage chondrocyte growth	TGF-beta receptor type-2	Homo sapiens (human)
apoptotic process	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	TGF-beta receptor type-2	Homo sapiens (human)
Notch signaling pathway	TGF-beta receptor type-2	Homo sapiens (human)
smoothened signaling pathway	TGF-beta receptor type-2	Homo sapiens (human)
gastrulation	TGF-beta receptor type-2	Homo sapiens (human)
brain development	TGF-beta receptor type-2	Homo sapiens (human)
heart development	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of cell population proliferation	TGF-beta receptor type-2	Homo sapiens (human)
response to xenobiotic stimulus	TGF-beta receptor type-2	Homo sapiens (human)
regulation of gene expression	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of epithelial cell migration	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition	TGF-beta receptor type-2	Homo sapiens (human)
activation of protein kinase activity	TGF-beta receptor type-2	Homo sapiens (human)
activin receptor signaling pathway	TGF-beta receptor type-2	Homo sapiens (human)
embryonic hemopoiesis	TGF-beta receptor type-2	Homo sapiens (human)
aorta morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
regulation of cell population proliferation	TGF-beta receptor type-2	Homo sapiens (human)
myeloid dendritic cell differentiation	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of angiogenesis	TGF-beta receptor type-2	Homo sapiens (human)
embryonic cranial skeleton morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
artery morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of NK T cell differentiation	TGF-beta receptor type-2	Homo sapiens (human)
roof of mouth development	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	TGF-beta receptor type-2	Homo sapiens (human)
SMAD protein signal transduction	TGF-beta receptor type-2	Homo sapiens (human)
ventricular septum morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
bronchus morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
trachea formation	TGF-beta receptor type-2	Homo sapiens (human)
mammary gland morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
lung lobe morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
Langerhans cell differentiation	TGF-beta receptor type-2	Homo sapiens (human)
secondary palate development	TGF-beta receptor type-2	Homo sapiens (human)
response to cholesterol	TGF-beta receptor type-2	Homo sapiens (human)
regulation of stem cell proliferation	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	TGF-beta receptor type-2	Homo sapiens (human)
inferior endocardial cushion morphogenesis	TGF-beta receptor type-2	Homo sapiens (human)
lens fiber cell apoptotic process	TGF-beta receptor type-2	Homo sapiens (human)
miRNA transport	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	TGF-beta receptor type-2	Homo sapiens (human)
positive regulation of CD4-positive, alpha-beta T cell proliferation	TGF-beta receptor type-2	Homo sapiens (human)
regulation of stem cell differentiation	TGF-beta receptor type-2	Homo sapiens (human)
cellular response to growth factor stimulus	TGF-beta receptor type-2	Homo sapiens (human)
protein phosphorylation	TGF-beta receptor type-2	Homo sapiens (human)
amino acid catabolic process	Electron transfer flavoprotein subunit beta	Homo sapiens (human)
respiratory electron transport chain	Electron transfer flavoprotein subunit beta	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA dehydrogenase	Electron transfer flavoprotein subunit beta	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of cell population proliferation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of low-density lipoprotein particle clearance	Tyrosine-protein kinase CSK	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of interleukin-6 production	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of Golgi to plasma membrane protein transport	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of bone resorption	Tyrosine-protein kinase CSK	Homo sapiens (human)
oligodendrocyte differentiation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of phagocytosis	Tyrosine-protein kinase CSK	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase CSK	Homo sapiens (human)
cellular response to peptide hormone stimulus	Tyrosine-protein kinase CSK	Homo sapiens (human)
regulation of Fc receptor mediated stimulatory signaling pathway	Tyrosine-protein kinase CSK	Homo sapiens (human)
adherens junction organization	Tyrosine-protein kinase CSK	Homo sapiens (human)
tRNA aminoacylation for protein translation	Glycine--tRNA ligase	Homo sapiens (human)
diadenosine tetraphosphate biosynthetic process	Glycine--tRNA ligase	Homo sapiens (human)
mitochondrial glycyl-tRNA aminoacylation	Glycine--tRNA ligase	Homo sapiens (human)
protein phosphorylation	Protein kinase C iota type	Homo sapiens (human)
protein targeting to membrane	Protein kinase C iota type	Homo sapiens (human)
cytoskeleton organization	Protein kinase C iota type	Homo sapiens (human)
actin filament organization	Protein kinase C iota type	Homo sapiens (human)
positive regulation of neuron projection development	Protein kinase C iota type	Homo sapiens (human)
vesicle-mediated transport	Protein kinase C iota type	Homo sapiens (human)
cell migration	Protein kinase C iota type	Homo sapiens (human)
cellular response to insulin stimulus	Protein kinase C iota type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C iota type	Homo sapiens (human)
establishment of apical/basal cell polarity	Protein kinase C iota type	Homo sapiens (human)
eye photoreceptor cell development	Protein kinase C iota type	Homo sapiens (human)
negative regulation of apoptotic process	Protein kinase C iota type	Homo sapiens (human)
negative regulation of neuron apoptotic process	Protein kinase C iota type	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Protein kinase C iota type	Homo sapiens (human)
cell-cell junction organization	Protein kinase C iota type	Homo sapiens (human)
positive regulation of Notch signaling pathway	Protein kinase C iota type	Homo sapiens (human)
positive regulation of glucose import	Protein kinase C iota type	Homo sapiens (human)
secretion	Protein kinase C iota type	Homo sapiens (human)
Golgi vesicle budding	Protein kinase C iota type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C iota type	Homo sapiens (human)
positive regulation of glial cell proliferation	Protein kinase C iota type	Homo sapiens (human)
membrane organization	Protein kinase C iota type	Homo sapiens (human)
cellular response to chemical stress	Protein kinase C iota type	Homo sapiens (human)
response to interleukin-1	Protein kinase C iota type	Homo sapiens (human)
regulation of postsynaptic membrane neurotransmitter receptor levels	Protein kinase C iota type	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Protein kinase C iota type	Homo sapiens (human)
positive regulation of endothelial cell apoptotic process	Protein kinase C iota type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C iota type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C iota type	Homo sapiens (human)
mRNA splicing, via spliceosome	Exosome RNA helicase MTR4	Homo sapiens (human)
maturation of 5.8S rRNA	Exosome RNA helicase MTR4	Homo sapiens (human)
rRNA processing	Exosome RNA helicase MTR4	Homo sapiens (human)
RNA catabolic process	Exosome RNA helicase MTR4	Homo sapiens (human)
DNA damage response	Exosome RNA helicase MTR4	Homo sapiens (human)
snRNA catabolic process	Exosome RNA helicase MTR4	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Tec	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase Tec	Homo sapiens (human)
regulation of platelet activation	Tyrosine-protein kinase Tec	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Tec	Homo sapiens (human)
tissue regeneration	Tyrosine-protein kinase Tec	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Tec	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase Tec	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase Tec	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of phospholipase C activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
negative regulation of Rho protein signal transduction	Tyrosine-protein kinase ABL2	Homo sapiens (human)
exploration behavior	Tyrosine-protein kinase ABL2	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase ABL2	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of autophagy	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase ABL2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of endocytosis	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of cell adhesion	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of actin cytoskeleton organization	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein modification process	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of oxidoreductase activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
cellular response to retinoic acid	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of establishment of T cell polarity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
regulation of cell motility	Tyrosine-protein kinase ABL2	Homo sapiens (human)
positive regulation of T cell migration	Tyrosine-protein kinase ABL2	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase ABL2	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Tyrosine-protein kinase FRK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase FRK	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase FRK	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase FRK	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase FRK	Homo sapiens (human)
protein import into nucleus	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of DNA-binding transcription factor activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
angiogenesis	Tyrosine-protein kinase SYK	Homo sapiens (human)
cell activation	Tyrosine-protein kinase SYK	Homo sapiens (human)
lymph vessel development	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of receptor internalization	Tyrosine-protein kinase SYK	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
macrophage activation involved in immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
neutrophil activation involved in immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
leukocyte activation involved in immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
serotonin secretion by platelet	Tyrosine-protein kinase SYK	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase SYK	Homo sapiens (human)
leukocyte cell-cell adhesion	Tyrosine-protein kinase SYK	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
animal organ morphogenesis	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of platelet activation	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of tumor necrosis factor-mediated signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase SYK	Homo sapiens (human)
leukotriene biosynthetic process	Tyrosine-protein kinase SYK	Homo sapiens (human)
calcium-mediated signaling	Tyrosine-protein kinase SYK	Homo sapiens (human)
platelet activation	Tyrosine-protein kinase SYK	Homo sapiens (human)
B cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
neutrophil chemotaxis	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of protein-containing complex assembly	Tyrosine-protein kinase SYK	Homo sapiens (human)
receptor internalization	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of type I interferon production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of granulocyte macrophage colony-stimulating factor production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-10 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-12 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-3 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-4 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-6 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of interleukin-8 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of mast cell cytokine production	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of superoxide anion generation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of superoxide anion generation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of cell adhesion mediated by integrin	Tyrosine-protein kinase SYK	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase SYK	Homo sapiens (human)
collagen-activated tyrosine kinase receptor signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase SYK	Homo sapiens (human)
interleukin-3-mediated signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
gamma-delta T cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
defense response to bacterium	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Tyrosine-protein kinase SYK	Homo sapiens (human)
mast cell degranulation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of mast cell degranulation	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of neutrophil degranulation	Tyrosine-protein kinase SYK	Homo sapiens (human)
beta selection	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of MAPK cascade	Tyrosine-protein kinase SYK	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of B cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of gamma-delta T cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of bone resorption	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of alpha-beta T cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of alpha-beta T cell proliferation	Tyrosine-protein kinase SYK	Homo sapiens (human)
blood vessel morphogenesis	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of phagocytosis	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Tyrosine-protein kinase SYK	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of killing of cells of another organism	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase SYK	Homo sapiens (human)
cellular response to molecule of fungal origin	Tyrosine-protein kinase SYK	Homo sapiens (human)
cellular response to lipid	Tyrosine-protein kinase SYK	Homo sapiens (human)
cellular response to low-density lipoprotein particle stimulus	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of monocyte chemotactic protein-1 production	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of arachidonic acid secretion	Tyrosine-protein kinase SYK	Homo sapiens (human)
regulation of platelet aggregation	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of cold-induced thermogenesis	Tyrosine-protein kinase SYK	Homo sapiens (human)
positive regulation of TORC1 signaling	Tyrosine-protein kinase SYK	Homo sapiens (human)
cellular response to lectin	Tyrosine-protein kinase SYK	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase SYK	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase SYK	Homo sapiens (human)
blastocyst development	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteolysis	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	26S proteasome regulatory subunit 6B	Homo sapiens (human)
positive regulation of proteasomal protein catabolic process	26S proteasome regulatory subunit 6B	Homo sapiens (human)
JUN phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
response to UV	Mitogen-activated protein kinase 8	Homo sapiens (human)
negative regulation of apoptotic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to lipopolysaccharide	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
response to oxidative stress	Mitogen-activated protein kinase 8	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase 8	Homo sapiens (human)
JUN phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of gene expression	Mitogen-activated protein kinase 8	Homo sapiens (human)
regulation of macroautophagy	Mitogen-activated protein kinase 8	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
peptidyl-threonine phosphorylation	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of cyclase activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of cell killing	Mitogen-activated protein kinase 8	Homo sapiens (human)
negative regulation of protein binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
regulation of protein localization	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to amino acid starvation	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to oxidative stress	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to reactive oxygen species	Mitogen-activated protein kinase 8	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Mitogen-activated protein kinase 8	Homo sapiens (human)
regulation of circadian rhythm	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
negative regulation of apoptotic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
rhythmic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of protein metabolic process	Mitogen-activated protein kinase 8	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to mechanical stimulus	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular response to cadmium ion	Mitogen-activated protein kinase 8	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 8	Homo sapiens (human)
energy homeostasis	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	Mitogen-activated protein kinase 8	Homo sapiens (human)
response to mechanical stimulus	Mitogen-activated protein kinase 8	Homo sapiens (human)
positive regulation of establishment of protein localization to mitochondrion	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 9	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of gene expression	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of macrophage derived foam cell differentiation	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of protein ubiquitination	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Mitogen-activated protein kinase 9	Homo sapiens (human)
cellular response to reactive oxygen species	Mitogen-activated protein kinase 9	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Mitogen-activated protein kinase 9	Homo sapiens (human)
regulation of circadian rhythm	Mitogen-activated protein kinase 9	Homo sapiens (human)
rhythmic process	Mitogen-activated protein kinase 9	Homo sapiens (human)
modulation of chemical synaptic transmission	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein localization to tricellular tight junction	Mitogen-activated protein kinase 9	Homo sapiens (human)
cellular response to cadmium ion	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of podosome assembly	Mitogen-activated protein kinase 9	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 9	Homo sapiens (human)
inflammatory response to wounding	Mitogen-activated protein kinase 9	Homo sapiens (human)
apoptotic signaling pathway	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of cytokine production involved in inflammatory response	Mitogen-activated protein kinase 9	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Mitogen-activated protein kinase 9	Homo sapiens (human)
regulation of cytokine production	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
response to ischemia	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
inflammatory response	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
heart development	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
negative regulation of hippo signaling	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
p38MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of protein kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cardiac muscle contraction	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cellular response to lipopolysaccharide	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cellular response to sorbitol	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cellular senescence	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
regulation of autophagy	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
megakaryocyte development	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
autophagosome-lysosome fusion	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
vesicle-mediated cholesterol transport	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
positive regulation of autophagosome assembly	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
protein phosphorylation	Casein kinase I isoform alpha	Homo sapiens (human)
Golgi organization	Casein kinase I isoform alpha	Homo sapiens (human)
cell surface receptor signaling pathway	Casein kinase I isoform alpha	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform alpha	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform alpha	Homo sapiens (human)
viral protein processing	Casein kinase I isoform alpha	Homo sapiens (human)
cellular response to nutrient	Casein kinase I isoform alpha	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Casein kinase I isoform alpha	Homo sapiens (human)
positive regulation of Rho protein signal transduction	Casein kinase I isoform alpha	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	Casein kinase I isoform alpha	Homo sapiens (human)
intermediate filament cytoskeleton organization	Casein kinase I isoform alpha	Homo sapiens (human)
cell division	Casein kinase I isoform alpha	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Casein kinase I isoform alpha	Homo sapiens (human)
negative regulation of NLRP3 inflammasome complex assembly	Casein kinase I isoform alpha	Homo sapiens (human)
positive regulation of TORC1 signaling	Casein kinase I isoform alpha	Homo sapiens (human)
signal transduction	Casein kinase I isoform alpha	Homo sapiens (human)
microtubule nucleation	Casein kinase I isoform delta	Homo sapiens (human)
Golgi organization	Casein kinase I isoform delta	Homo sapiens (human)
protein localization to Golgi apparatus	Casein kinase I isoform delta	Homo sapiens (human)
protein localization to cilium	Casein kinase I isoform delta	Homo sapiens (human)
protein localization to centrosome	Casein kinase I isoform delta	Homo sapiens (human)
non-motile cilium assembly	Casein kinase I isoform delta	Homo sapiens (human)
positive regulation of protein phosphorylation	Casein kinase I isoform delta	Homo sapiens (human)
protein phosphorylation	Casein kinase I isoform delta	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform delta	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Casein kinase I isoform delta	Homo sapiens (human)
circadian regulation of gene expression	Casein kinase I isoform delta	Homo sapiens (human)
regulation of circadian rhythm	Casein kinase I isoform delta	Homo sapiens (human)
COPII vesicle coating	Casein kinase I isoform delta	Homo sapiens (human)
spindle assembly	Casein kinase I isoform delta	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform delta	Homo sapiens (human)
midbrain dopaminergic neuron differentiation	Casein kinase I isoform delta	Homo sapiens (human)
cellular response to nerve growth factor stimulus	Casein kinase I isoform delta	Homo sapiens (human)
positive regulation of non-canonical Wnt signaling pathway	Casein kinase I isoform delta	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform delta	Homo sapiens (human)
signal transduction	Casein kinase I isoform delta	Homo sapiens (human)
non-motile cilium assembly	Casein kinase I isoform delta	Homo sapiens (human)
endocytosis	Casein kinase I isoform delta	Homo sapiens (human)
MAPK cascade	MAP kinase-activated protein kinase 2	Homo sapiens (human)
toll-like receptor signaling pathway	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein phosphorylation	MAP kinase-activated protein kinase 2	Homo sapiens (human)
leukotriene metabolic process	MAP kinase-activated protein kinase 2	Homo sapiens (human)
inflammatory response	MAP kinase-activated protein kinase 2	Homo sapiens (human)
DNA damage response	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of tumor necrosis factor-mediated signaling pathway	MAP kinase-activated protein kinase 2	Homo sapiens (human)
peptidyl-serine phosphorylation	MAP kinase-activated protein kinase 2	Homo sapiens (human)
response to lipopolysaccharide	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of interleukin-6 production	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of tumor necrosis factor production	MAP kinase-activated protein kinase 2	Homo sapiens (human)
positive regulation of tumor necrosis factor production	MAP kinase-activated protein kinase 2	Homo sapiens (human)
response to cytokine	MAP kinase-activated protein kinase 2	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	MAP kinase-activated protein kinase 2	Homo sapiens (human)
p38MAPK cascade	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of mRNA stability	MAP kinase-activated protein kinase 2	Homo sapiens (human)
macropinocytosis	MAP kinase-activated protein kinase 2	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	MAP kinase-activated protein kinase 2	Homo sapiens (human)
inner ear development	MAP kinase-activated protein kinase 2	Homo sapiens (human)
positive regulation of macrophage cytokine production	MAP kinase-activated protein kinase 2	Homo sapiens (human)
3'-UTR-mediated mRNA stabilization	MAP kinase-activated protein kinase 2	Homo sapiens (human)
regulation of cellular response to heat	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein autophosphorylation	MAP kinase-activated protein kinase 2	Homo sapiens (human)
intracellular signal transduction	MAP kinase-activated protein kinase 2	Homo sapiens (human)
translational elongation	Elongation factor Tu, mitochondrial	Homo sapiens (human)
response to ethanol	Elongation factor Tu, mitochondrial	Homo sapiens (human)
mitochondrial translational elongation	Elongation factor Tu, mitochondrial	Homo sapiens (human)
cysteinyl-tRNA aminoacylation	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
DNA repair	Casein kinase I isoform epsilon	Homo sapiens (human)
protein phosphorylation	Casein kinase I isoform epsilon	Homo sapiens (human)
protein localization	Casein kinase I isoform epsilon	Homo sapiens (human)
negative regulation of Wnt signaling pathway	Casein kinase I isoform epsilon	Homo sapiens (human)
negative regulation of protein binding	Casein kinase I isoform epsilon	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Casein kinase I isoform epsilon	Homo sapiens (human)
regulation of protein localization	Casein kinase I isoform epsilon	Homo sapiens (human)
circadian regulation of gene expression	Casein kinase I isoform epsilon	Homo sapiens (human)
regulation of circadian rhythm	Casein kinase I isoform epsilon	Homo sapiens (human)
circadian behavior	Casein kinase I isoform epsilon	Homo sapiens (human)
canonical Wnt signaling pathway	Casein kinase I isoform epsilon	Homo sapiens (human)
positive regulation of amyloid-beta formation	Casein kinase I isoform epsilon	Homo sapiens (human)
cellular response to nerve growth factor stimulus	Casein kinase I isoform epsilon	Homo sapiens (human)
positive regulation of non-canonical Wnt signaling pathway	Casein kinase I isoform epsilon	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform epsilon	Homo sapiens (human)
endocytosis	Casein kinase I isoform epsilon	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform epsilon	Homo sapiens (human)
signal transduction	Casein kinase I isoform epsilon	Homo sapiens (human)
temperature homeostasis	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
response to cold	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
energy derivation by oxidation of organic compounds	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
epithelial cell differentiation	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA dehydrogenase	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
negative regulation of fatty acid biosynthetic process	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
negative regulation of fatty acid oxidation	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
regulation of cholesterol metabolic process	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
regulation of RNA splicing	Dual specificity protein kinase CLK1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein phosphorylation	Dual specificity protein kinase CLK2	Homo sapiens (human)
response to ionizing radiation	Dual specificity protein kinase CLK2	Homo sapiens (human)
regulation of RNA splicing	Dual specificity protein kinase CLK2	Homo sapiens (human)
negative regulation of gluconeogenesis	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein autophosphorylation	Dual specificity protein kinase CLK2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein phosphorylation	Dual specificity protein kinase CLK3	Homo sapiens (human)
regulation of RNA splicing	Dual specificity protein kinase CLK3	Homo sapiens (human)
regulation of systemic arterial blood pressure	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cardiac left ventricle morphogenesis	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
glycogen metabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protein phosphorylation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
dopamine receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
nervous system development	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
insulin receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of autophagy	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of gene expression	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of UDP-glucose catabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
Wnt signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cell migration	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
peptidyl-threonine phosphorylation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
viral protein processing	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of protein ubiquitination	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of TOR signaling	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cellular response to insulin stimulus	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cellular response to interleukin-3	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of glycogen biosynthetic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of protein catabolic process	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of heart contraction	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of glucose import	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
excitatory postsynaptic potential	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of cell growth involved in cardiac muscle cell development	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cellular response to lithium ion	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cellular response to glucocorticoid stimulus	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligand	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
autosome genomic imprinting	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
regulation of mitophagy	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of amyloid-beta formation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of protein targeting to mitochondrion	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of glycogen synthase activity, transferring glucose-1-phosphate	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of type B pancreatic cell development	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
negative regulation of glycogen (starch) synthase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of glycogen (starch) synthase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cell differentiation	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
regulation of neuron projection development	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
positive regulation of gene expression	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of gene expression	Glycogen synthase kinase-3 beta	Homo sapiens (human)
ER overload response	Glycogen synthase kinase-3 beta	Homo sapiens (human)
peptidyl-serine phosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
intracellular signal transduction	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of apoptotic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein export from nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
epithelial to mesenchymal transition	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Glycogen synthase kinase-3 beta	Homo sapiens (human)
glycogen metabolic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein phosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
mitochondrion organization	Glycogen synthase kinase-3 beta	Homo sapiens (human)
dopamine receptor signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
circadian rhythm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of autophagy	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of gene expression	Glycogen synthase kinase-3 beta	Homo sapiens (human)
peptidyl-serine phosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
peptidyl-threonine phosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
viral protein processing	Glycogen synthase kinase-3 beta	Homo sapiens (human)
hippocampus development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
establishment of cell polarity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
maintenance of cell polarity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of cell migration	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of axon extension	Glycogen synthase kinase-3 beta	Homo sapiens (human)
neuron projection development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein-containing complex assembly	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein ubiquitination	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of phosphoprotein phosphatase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of microtubule-based process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
intracellular signal transduction	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cellular response to interleukin-3	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of circadian rhythm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
proteasome-mediated ubiquitin-dependent protein catabolic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of GTPase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of cell differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of osteoblast differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of glycogen biosynthetic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of cilium assembly	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein catabolic process	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein autophosphorylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of protein export from nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of dendrite morphogenesis	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of axonogenesis	Glycogen synthase kinase-3 beta	Homo sapiens (human)
canonical Wnt signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
excitatory postsynaptic potential	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of calcineurin-NFAT signaling cascade	Glycogen synthase kinase-3 beta	Homo sapiens (human)
superior temporal gyrus development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cellular response to retinoic acid	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
extrinsic apoptotic signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
extrinsic apoptotic signaling pathway in absence of ligand	Glycogen synthase kinase-3 beta	Homo sapiens (human)
presynaptic modulation of chemical synaptic transmission	Glycogen synthase kinase-3 beta	Homo sapiens (human)
neuron projection organization	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of microtubule anchoring at centrosome	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of cellular response to heat	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of protein localization to nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of long-term synaptic potentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of protein acetylation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein localization to cilium	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of dopaminergic neuron differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cellular response to amyloid-beta	Glycogen synthase kinase-3 beta	Homo sapiens (human)
positive regulation of protein localization to centrosome	Glycogen synthase kinase-3 beta	Homo sapiens (human)
beta-catenin destruction complex disassembly	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of type B pancreatic cell development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of glycogen (starch) synthase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of mesenchymal stem cell differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
negative regulation of TOR signaling	Glycogen synthase kinase-3 beta	Homo sapiens (human)
regulation of neuron projection development	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cell differentiation	Glycogen synthase kinase-3 beta	Homo sapiens (human)
insulin receptor signaling pathway	Glycogen synthase kinase-3 beta	Homo sapiens (human)
DNA repair	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription by RNA polymerase II	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription initiation at RNA polymerase II promoter	Cyclin-dependent kinase 7	Homo sapiens (human)
snRNA transcription by RNA polymerase II	Cyclin-dependent kinase 7	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 7	Homo sapiens (human)
protein stabilization	Cyclin-dependent kinase 7	Homo sapiens (human)
cell division	Cyclin-dependent kinase 7	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 7	Homo sapiens (human)
regulation of G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 7	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 7	Homo sapiens (human)
regulation of mitotic cell cycle	Cyclin-dependent kinase 9	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 9	Homo sapiens (human)
DNA repair	Cyclin-dependent kinase 9	Homo sapiens (human)
regulation of DNA repair	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription by RNA polymerase II	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription initiation at RNA polymerase II promoter	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription elongation by RNA polymerase II	Cyclin-dependent kinase 9	Homo sapiens (human)
cell population proliferation	Cyclin-dependent kinase 9	Homo sapiens (human)
replication fork processing	Cyclin-dependent kinase 9	Homo sapiens (human)
regulation of mRNA 3'-end processing	Cyclin-dependent kinase 9	Homo sapiens (human)
positive regulation of transcription elongation by RNA polymerase II	Cyclin-dependent kinase 9	Homo sapiens (human)
positive regulation by host of viral transcription	Cyclin-dependent kinase 9	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 9	Homo sapiens (human)
regulation of muscle cell differentiation	Cyclin-dependent kinase 9	Homo sapiens (human)
nucleus localization	Cyclin-dependent kinase 9	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 9	Homo sapiens (human)
cellular response to cytokine stimulus	Cyclin-dependent kinase 9	Homo sapiens (human)
negative regulation of protein localization to chromatin	Cyclin-dependent kinase 9	Homo sapiens (human)
positive regulation of protein localization to chromatin	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription elongation-coupled chromatin remodeling	Cyclin-dependent kinase 9	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 9	Homo sapiens (human)
exocytosis	Ras-related protein Rab-27A	Homo sapiens (human)
blood coagulation	Ras-related protein Rab-27A	Homo sapiens (human)
protein secretion	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of gene expression	Ras-related protein Rab-27A	Homo sapiens (human)
antigen processing and presentation	Ras-related protein Rab-27A	Homo sapiens (human)
melanocyte differentiation	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome localization	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome transport	Ras-related protein Rab-27A	Homo sapiens (human)
multivesicular body organization	Ras-related protein Rab-27A	Homo sapiens (human)
cytotoxic T cell degranulation	Ras-related protein Rab-27A	Homo sapiens (human)
natural killer cell degranulation	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of exocytosis	Ras-related protein Rab-27A	Homo sapiens (human)
synaptic vesicle transport	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of phagocytosis	Ras-related protein Rab-27A	Homo sapiens (human)
multivesicular body sorting pathway	Ras-related protein Rab-27A	Homo sapiens (human)
complement-dependent cytotoxicity	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of regulated secretory pathway	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of reactive oxygen species biosynthetic process	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of constitutive secretory pathway	Ras-related protein Rab-27A	Homo sapiens (human)
exosomal secretion	Ras-related protein Rab-27A	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein autophosphorylation	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
regulation of cytokine-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
JNK cascade	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
negative regulation of NF-kappaB transcription factor activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of type I interferon production	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
toll-like receptor 2 signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
toll-like receptor 9 signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cellular response to heat	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
interleukin-33-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein autophosphorylation	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
type I interferon-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
response to interleukin-1	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cellular response to hypoxia	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of leukocyte adhesion to vascular endothelial cell	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
positive regulation of MAP kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cellular response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
intracellular signal transduction	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
Toll signaling pathway	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
innate immune response	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
skeletal system development	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
toll-like receptor signaling pathway	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
signal transduction	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
chemical synaptic transmission	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
central nervous system development	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
positive regulation of cell growth	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
response to lipopolysaccharide	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
intracellular signal transduction	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
negative regulation of apoptotic process	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
regulation of translation in response to stress	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
positive regulation of cell differentiation	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
mitotic cell cycle	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
blastocyst development	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
chromosome segregation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
regulation of mitotic nuclear division	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
regulation of mitotic centrosome separation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
spindle assembly	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
centrosome separation	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
meiotic cell cycle	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
positive regulation of telomerase activity	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
regulation of attachment of spindle microtubules to kinetochore	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
mitotic spindle assembly	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
negative regulation of centriole-centriole cohesion	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
positive regulation of telomere capping	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
mitotic cell cycle	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
establishment of cell polarity	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
neuron projection morphogenesis	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
regulation of tubulin deacetylation	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
osteoblast differentiation	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of protein phosphorylation	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
response to ischemia	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
apoptotic process	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
response to xenobiotic stimulus	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
ovulation cycle process	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of prostaglandin secretion	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
p38MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
signal transduction in response to DNA damage	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of apoptotic process	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
stress-activated MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
regulation of cell cycle	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cardiac muscle contraction	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
bone development	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cellular response to sorbitol	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cellular senescence	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
establishment of protein localization	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic sister chromatid segregation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
establishment of mitotic spindle orientation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic cytokinesis	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
microtubule bundle formation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
double-strand break repair	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic spindle organization	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
sister chromatid cohesion	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic chromosome condensation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic nuclear membrane disassembly	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
metaphase/anaphase transition of mitotic cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic spindle assembly checkpoint signaling	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centrosome cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
female meiosis chromosome segregation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein ubiquitination	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of mitotic metaphase/anaphase transition	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein destabilization	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of cytokinesis	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of protein binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
homologous chromosome segregation	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
negative regulation of cyclin-dependent protein serine/threonine kinase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of proteolysis	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
Golgi inheritance	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
nuclear membrane disassembly	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of ubiquitin-protein transferase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of cell cycle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
synaptonemal complex disassembly	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein localization to chromatin	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein localization to nuclear envelope	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
double-strand break repair via alternative nonhomologous end joining	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of protein localization to nucleus	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of mitotic spindle assembly	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of mitotic cell cycle phase transition	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
positive regulation of ubiquitin protein ligase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of protein localization to cell cortex	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
regulation of anaphase-promoting complex-dependent catabolic process	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
negative regulation of double-strand break repair via homologous recombination	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein phosphorylation	LIM domain kinase 1	Homo sapiens (human)
signal transduction	LIM domain kinase 1	Homo sapiens (human)
Rho protein signal transduction	LIM domain kinase 1	Homo sapiens (human)
nervous system development	LIM domain kinase 1	Homo sapiens (human)
positive regulation of actin filament bundle assembly	LIM domain kinase 1	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	LIM domain kinase 1	Homo sapiens (human)
stress fiber assembly	LIM domain kinase 1	Homo sapiens (human)
positive regulation of axon extension	LIM domain kinase 1	Homo sapiens (human)
axon extension	LIM domain kinase 1	Homo sapiens (human)
negative regulation of ubiquitin-protein transferase activity	LIM domain kinase 1	Homo sapiens (human)
positive regulation of stress fiber assembly	LIM domain kinase 1	Homo sapiens (human)
actin cytoskeleton organization	LIM domain kinase 1	Homo sapiens (human)
positive regulation of protein phosphorylation	LIM domain kinase 2	Homo sapiens (human)
protein phosphorylation	LIM domain kinase 2	Homo sapiens (human)
spermatogenesis	LIM domain kinase 2	Homo sapiens (human)
phosphorylation	LIM domain kinase 2	Homo sapiens (human)
astral microtubule organization	LIM domain kinase 2	Homo sapiens (human)
establishment of vesicle localization	LIM domain kinase 2	Homo sapiens (human)
head development	LIM domain kinase 2	Homo sapiens (human)
cornea development in camera-type eye	LIM domain kinase 2	Homo sapiens (human)
positive regulation of protein localization to nucleus	LIM domain kinase 2	Homo sapiens (human)
negative regulation of cilium assembly	LIM domain kinase 2	Homo sapiens (human)
actin cytoskeleton organization	LIM domain kinase 2	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase 10	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 10	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase 10	Homo sapiens (human)
response to light stimulus	Mitogen-activated protein kinase 10	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Mitogen-activated protein kinase 10	Homo sapiens (human)
regulation of circadian rhythm	Mitogen-activated protein kinase 10	Homo sapiens (human)
rhythmic process	Mitogen-activated protein kinase 10	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 10	Homo sapiens (human)
tyrosyl-tRNA aminoacylation	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
apoptotic process	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
response to starvation	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
regulation of glycolytic process	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
protein phosphorylation	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
fatty acid biosynthetic process	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
signal transduction	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
spermatogenesis	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
positive regulation of gene expression	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cellular response to nutrient levels	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
positive regulation of protein kinase activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
import into nucleus	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
regulation of catalytic activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
angiogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
urogenital system development	Ephrin type-B receptor 3	Homo sapiens (human)
axon guidance	Ephrin type-B receptor 3	Homo sapiens (human)
axonal fasciculation	Ephrin type-B receptor 3	Homo sapiens (human)
cell migration	Ephrin type-B receptor 3	Homo sapiens (human)
central nervous system projection neuron axonogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
corpus callosum development	Ephrin type-B receptor 3	Homo sapiens (human)
regulation of cell-cell adhesion	Ephrin type-B receptor 3	Homo sapiens (human)
retinal ganglion cell axon guidance	Ephrin type-B receptor 3	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Ephrin type-B receptor 3	Homo sapiens (human)
regulation of GTPase activity	Ephrin type-B receptor 3	Homo sapiens (human)
protein autophosphorylation	Ephrin type-B receptor 3	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-B receptor 3	Homo sapiens (human)
thymus development	Ephrin type-B receptor 3	Homo sapiens (human)
digestive tract morphogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
regulation of axonogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
positive regulation of synapse assembly	Ephrin type-B receptor 3	Homo sapiens (human)
roof of mouth development	Ephrin type-B receptor 3	Homo sapiens (human)
dendritic spine development	Ephrin type-B receptor 3	Homo sapiens (human)
dendritic spine morphogenesis	Ephrin type-B receptor 3	Homo sapiens (human)
protein phosphorylation	Ephrin type-B receptor 3	Homo sapiens (human)
axon guidance	Ephrin type-A receptor 5	Homo sapiens (human)
cAMP-mediated signaling	Ephrin type-A receptor 5	Homo sapiens (human)
hippocampus development	Ephrin type-A receptor 5	Homo sapiens (human)
positive regulation of CREB transcription factor activity	Ephrin type-A receptor 5	Homo sapiens (human)
regulation of actin cytoskeleton organization	Ephrin type-A receptor 5	Homo sapiens (human)
regulation of GTPase activity	Ephrin type-A receptor 5	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 5	Homo sapiens (human)
neuron development	Ephrin type-A receptor 5	Homo sapiens (human)
regulation of insulin secretion involved in cellular response to glucose stimulus	Ephrin type-A receptor 5	Homo sapiens (human)
protein phosphorylation	Ephrin type-A receptor 5	Homo sapiens (human)
angiogenesis	Ephrin type-B receptor 4	Homo sapiens (human)
cell migration involved in sprouting angiogenesis	Ephrin type-B receptor 4	Homo sapiens (human)
heart morphogenesis	Ephrin type-B receptor 4	Homo sapiens (human)
cell adhesion	Ephrin type-B receptor 4	Homo sapiens (human)
protein autophosphorylation	Ephrin type-B receptor 4	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-B receptor 4	Homo sapiens (human)
multicellular organism development	Ephrin type-B receptor 4	Homo sapiens (human)
positive regulation of kinase activity	Ephrin type-B receptor 4	Homo sapiens (human)
negative regulation of cellular response to hypoxia	Ephrin type-A receptor 4	Homo sapiens (human)
cell adhesion	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of cell adhesion	Ephrin type-A receptor 4	Homo sapiens (human)
adult walking behavior	Ephrin type-A receptor 4	Homo sapiens (human)
motor neuron axon guidance	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of cell population proliferation	Ephrin type-A receptor 4	Homo sapiens (human)
glial cell migration	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of epithelial to mesenchymal transition	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of neuron projection development	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of translation	Ephrin type-A receptor 4	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Ephrin type-A receptor 4	Homo sapiens (human)
corticospinal tract morphogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of cell migration	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of cell migration	Ephrin type-A receptor 4	Homo sapiens (human)
adherens junction organization	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of GTPase activity	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of cell adhesion	Ephrin type-A receptor 4	Homo sapiens (human)
protein autophosphorylation	Ephrin type-A receptor 4	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of axon regeneration	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of astrocyte differentiation	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of axonogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of dendrite morphogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
protein stabilization	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of dendritic spine morphogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of protein tyrosine kinase activity	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Ephrin type-A receptor 4	Homo sapiens (human)
nephric duct morphogenesis	Ephrin type-A receptor 4	Homo sapiens (human)
cochlea development	Ephrin type-A receptor 4	Homo sapiens (human)
fasciculation of sensory neuron axon	Ephrin type-A receptor 4	Homo sapiens (human)
fasciculation of motor neuron axon	Ephrin type-A receptor 4	Homo sapiens (human)
neuron projection guidance	Ephrin type-A receptor 4	Homo sapiens (human)
synapse pruning	Ephrin type-A receptor 4	Homo sapiens (human)
neuron projection fasciculation	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of long-term synaptic potentiation	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of amyloid-beta formation	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Ephrin type-A receptor 4	Homo sapiens (human)
negative regulation of proteolysis involved in protein catabolic process	Ephrin type-A receptor 4	Homo sapiens (human)
cellular response to amyloid-beta	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of modification of synaptic structure	Ephrin type-A receptor 4	Homo sapiens (human)
regulation of synapse pruning	Ephrin type-A receptor 4	Homo sapiens (human)
positive regulation of Rho guanyl-nucleotide exchange factor activity	Ephrin type-A receptor 4	Homo sapiens (human)
protein phosphorylation	Ephrin type-A receptor 4	Homo sapiens (human)
axon guidance	Ephrin type-A receptor 4	Homo sapiens (human)
ADP biosynthetic process	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
nucleobase-containing small molecule interconversion	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
AMP metabolic process	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
ATP metabolic process	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
nucleoside monophosphate phosphorylation	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
purine ribonucleoside salvage	Adenosine kinase	Homo sapiens (human)
dATP biosynthetic process	Adenosine kinase	Homo sapiens (human)
ribonucleoside monophosphate biosynthetic process	Adenosine kinase	Homo sapiens (human)
GMP salvage	Adenosine kinase	Homo sapiens (human)
AMP salvage	Adenosine kinase	Homo sapiens (human)
dAMP salvage	Adenosine kinase	Homo sapiens (human)
purine nucleobase metabolic process	Adenosine kinase	Homo sapiens (human)
Golgi to plasma membrane transport	Ras-related protein Rab-10	Homo sapiens (human)
axonogenesis	Ras-related protein Rab-10	Homo sapiens (human)
vesicle-mediated transport	Ras-related protein Rab-10	Homo sapiens (human)
endosomal transport	Ras-related protein Rab-10	Homo sapiens (human)
antigen processing and presentation	Ras-related protein Rab-10	Homo sapiens (human)
polarized epithelial cell differentiation	Ras-related protein Rab-10	Homo sapiens (human)
cellular response to insulin stimulus	Ras-related protein Rab-10	Homo sapiens (human)
Golgi to plasma membrane protein transport	Ras-related protein Rab-10	Homo sapiens (human)
regulated exocytosis	Ras-related protein Rab-10	Homo sapiens (human)
establishment of neuroblast polarity	Ras-related protein Rab-10	Homo sapiens (human)
endoplasmic reticulum tubular network organization	Ras-related protein Rab-10	Homo sapiens (human)
protein localization to plasma membrane	Ras-related protein Rab-10	Homo sapiens (human)
establishment of protein localization to membrane	Ras-related protein Rab-10	Homo sapiens (human)
establishment of protein localization to endoplasmic reticulum membrane	Ras-related protein Rab-10	Homo sapiens (human)
cell-cell adhesion	Ras-related protein Rab-10	Homo sapiens (human)
protein localization to basolateral plasma membrane	Ras-related protein Rab-10	Homo sapiens (human)
exocytosis	Ras-related protein Rab-10	Homo sapiens (human)
protein secretion	Ras-related protein Rab-10	Homo sapiens (human)
establishment or maintenance of cell polarity	Actin-related protein 3	Homo sapiens (human)
asymmetric cell division	Actin-related protein 3	Homo sapiens (human)
positive regulation of lamellipodium assembly	Actin-related protein 3	Homo sapiens (human)
meiotic chromosome movement towards spindle pole	Actin-related protein 3	Homo sapiens (human)
meiotic cytokinesis	Actin-related protein 3	Homo sapiens (human)
Arp2/3 complex-mediated actin nucleation	Actin-related protein 3	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Actin-related protein 3	Homo sapiens (human)
spindle localization	Actin-related protein 3	Homo sapiens (human)
cilium assembly	Actin-related protein 3	Homo sapiens (human)
actin polymerization-dependent cell motility	Actin-related protein 3	Homo sapiens (human)
cellular response to type II interferon	Actin-related protein 3	Homo sapiens (human)
regulation of double-strand break repair via nonhomologous end joining	Actin-related protein 2	Homo sapiens (human)
cilium assembly	Actin-related protein 2	Homo sapiens (human)
establishment or maintenance of cell polarity	Actin-related protein 2	Homo sapiens (human)
asymmetric cell division	Actin-related protein 2	Homo sapiens (human)
positive regulation of lamellipodium assembly	Actin-related protein 2	Homo sapiens (human)
meiotic chromosome movement towards spindle pole	Actin-related protein 2	Homo sapiens (human)
cytosolic transport	Actin-related protein 2	Homo sapiens (human)
meiotic cytokinesis	Actin-related protein 2	Homo sapiens (human)
Arp2/3 complex-mediated actin nucleation	Actin-related protein 2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Actin-related protein 2	Homo sapiens (human)
spindle localization	Actin-related protein 2	Homo sapiens (human)
cellular response to type II interferon	Actin-related protein 2	Homo sapiens (human)
positive regulation of double-strand break repair via homologous recombination	Actin-related protein 2	Homo sapiens (human)
ribosomal large subunit export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
ribosomal small subunit export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
mitotic sister chromatid segregation	GTP-binding nuclear protein Ran	Homo sapiens (human)
mitotic cell cycle	GTP-binding nuclear protein Ran	Homo sapiens (human)
DNA metabolic process	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein import into nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
mitotic spindle organization	GTP-binding nuclear protein Ran	Homo sapiens (human)
spermatid development	GTP-binding nuclear protein Ran	Homo sapiens (human)
viral process	GTP-binding nuclear protein Ran	Homo sapiens (human)
hippocampus development	GTP-binding nuclear protein Ran	Homo sapiens (human)
actin cytoskeleton organization	GTP-binding nuclear protein Ran	Homo sapiens (human)
positive regulation of protein binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
pre-miRNA export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
positive regulation of protein import into nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
GTP metabolic process	GTP-binding nuclear protein Ran	Homo sapiens (human)
cell division	GTP-binding nuclear protein Ran	Homo sapiens (human)
snRNA import into nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
cellular response to mineralocorticoid stimulus	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein localization to nucleolus	GTP-binding nuclear protein Ran	Homo sapiens (human)
ribosomal subunit export from nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein phosphorylation	Casein kinase I isoform gamma-2	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform gamma-2	Homo sapiens (human)
sphingolipid biosynthetic process	Casein kinase I isoform gamma-2	Homo sapiens (human)
signal transduction	Casein kinase I isoform gamma-2	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform gamma-2	Homo sapiens (human)
endocytosis	Casein kinase I isoform gamma-2	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform gamma-2	Homo sapiens (human)
DNA damage response	Cyclin-dependent kinase 3	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 3	Homo sapiens (human)
cell population proliferation	Cyclin-dependent kinase 3	Homo sapiens (human)
G0 to G1 transition	Cyclin-dependent kinase 3	Homo sapiens (human)
negative regulation of Notch signaling pathway	Cyclin-dependent kinase 3	Homo sapiens (human)
cell division	Cyclin-dependent kinase 3	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 3	Homo sapiens (human)
response to organic substance	Cyclin-dependent kinase 3	Homo sapiens (human)
signal transduction	Cyclin-dependent kinase 3	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 3	Homo sapiens (human)
regulation of gene expression	Cyclin-dependent kinase 3	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 6	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Cyclin-dependent kinase 6	Homo sapiens (human)
type B pancreatic cell development	Cyclin-dependent kinase 6	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 6	Homo sapiens (human)
Notch signaling pathway	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of cell population proliferation	Cyclin-dependent kinase 6	Homo sapiens (human)
response to virus	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of gene expression	Cyclin-dependent kinase 6	Homo sapiens (human)
positive regulation of gene expression	Cyclin-dependent kinase 6	Homo sapiens (human)
astrocyte development	Cyclin-dependent kinase 6	Homo sapiens (human)
dentate gyrus development	Cyclin-dependent kinase 6	Homo sapiens (human)
lateral ventricle development	Cyclin-dependent kinase 6	Homo sapiens (human)
T cell differentiation in thymus	Cyclin-dependent kinase 6	Homo sapiens (human)
gliogenesis	Cyclin-dependent kinase 6	Homo sapiens (human)
cell dedifferentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of cell differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of myeloid cell differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of erythrocyte differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of monocyte differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of osteoblast differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of cell cycle	Cyclin-dependent kinase 6	Homo sapiens (human)
positive regulation of fibroblast proliferation	Cyclin-dependent kinase 6	Homo sapiens (human)
generation of neurons	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of epithelial cell proliferation	Cyclin-dependent kinase 6	Homo sapiens (human)
cell division	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 6	Homo sapiens (human)
hematopoietic stem cell differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of hematopoietic stem cell differentiation	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of cell motility	Cyclin-dependent kinase 6	Homo sapiens (human)
negative regulation of cellular senescence	Cyclin-dependent kinase 6	Homo sapiens (human)
regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 6	Homo sapiens (human)
response to organic substance	Cyclin-dependent kinase 6	Homo sapiens (human)
signal transduction	Cyclin-dependent kinase 6	Homo sapiens (human)
microtubule cytoskeleton organization	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron migration	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic transmission, dopaminergic	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
intracellular protein transport	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cell-matrix adhesion	Cyclin-dependent-like kinase 5	Homo sapiens (human)
chemical synaptic transmission	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synapse assembly	Cyclin-dependent-like kinase 5	Homo sapiens (human)
skeletal muscle tissue development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
motor neuron axon guidance	Cyclin-dependent-like kinase 5	Homo sapiens (human)
visual learning	Cyclin-dependent-like kinase 5	Homo sapiens (human)
Schwann cell development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic vesicle exocytosis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of macroautophagy	Cyclin-dependent-like kinase 5	Homo sapiens (human)
phosphorylation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
peptidyl-serine phosphorylation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
peptidyl-threonine phosphorylation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
sensory perception of pain	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cerebellar cortex formation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
hippocampus development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
layer formation in cerebral cortex	Cyclin-dependent-like kinase 5	Homo sapiens (human)
central nervous system neuron development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
corpus callosum development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron differentiation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of cell migration	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of axon extension	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron projection development	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of protein ubiquitination	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of synaptic plasticity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
receptor catabolic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic transmission, glutamatergic	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein localization to synapse	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of apoptotic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
receptor clustering	Cyclin-dependent-like kinase 5	Homo sapiens (human)
positive regulation of neuron apoptotic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of cell cycle	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of proteolysis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of DNA-templated transcription	Cyclin-dependent-like kinase 5	Homo sapiens (human)
positive regulation of calcium ion-dependent exocytosis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
negative regulation of protein export from nucleus	Cyclin-dependent-like kinase 5	Homo sapiens (human)
behavioral response to cocaine	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of synaptic plasticity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic vesicle endocytosis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
rhythmic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
axon extension	Cyclin-dependent-like kinase 5	Homo sapiens (human)
oligodendrocyte differentiation	Cyclin-dependent-like kinase 5	Homo sapiens (human)
dendrite morphogenesis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cell division	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron apoptotic process	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of synaptic transmission, glutamatergic	Cyclin-dependent-like kinase 5	Homo sapiens (human)
excitatory postsynaptic potential	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of dendritic spine morphogenesis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
calcium ion import	Cyclin-dependent-like kinase 5	Homo sapiens (human)
positive regulation of protein targeting to membrane	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of protein localization to plasma membrane	Cyclin-dependent-like kinase 5	Homo sapiens (human)
regulation of synaptic vesicle recycling	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cellular response to amyloid-beta	Cyclin-dependent-like kinase 5	Homo sapiens (human)
axonogenesis	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic vesicle transport	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 16	Homo sapiens (human)
exocytosis	Cyclin-dependent kinase 16	Homo sapiens (human)
spermatogenesis	Cyclin-dependent kinase 16	Homo sapiens (human)
positive regulation of autophagy	Cyclin-dependent kinase 16	Homo sapiens (human)
growth hormone secretion	Cyclin-dependent kinase 16	Homo sapiens (human)
neuron projection development	Cyclin-dependent kinase 16	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 16	Homo sapiens (human)
regulation of insulin secretion involved in cellular response to glucose stimulus	Cyclin-dependent kinase 16	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 17	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 17	Homo sapiens (human)
cellular response to leukemia inhibitory factor	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
canonical glycolysis	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
fructose 1,6-bisphosphate metabolic process	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
fructose 6-phosphate metabolic process	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
chemotaxis	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
heart development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
negative regulation of cell population proliferation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of gene expression	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
Schwann cell development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
cerebellar cortex formation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
keratinocyte differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
thyroid gland development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
regulation of stress-activated MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
endodermal cell differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
ERBB2-ERBB3 signaling pathway	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
myelination	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
type B pancreatic cell proliferation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
thymus development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
regulation of axon regeneration	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
cell motility	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of axonogenesis	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
Bergmann glial cell differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
face development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
trachea formation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
epithelial cell proliferation involved in lung morphogenesis	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
placenta blood vessel development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
labyrinthine layer development	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
ERK1 and ERK2 cascade	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
regulation of Golgi inheritance	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
cellular senescence	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of endodermal cell differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
regulation of early endosome to late endosome transport	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
neuron differentiation	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Angiopoietin-1 receptor	Homo sapiens (human)
angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
response to hypoxia	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	Angiopoietin-1 receptor	Homo sapiens (human)
endothelial cell proliferation	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Angiopoietin-1 receptor	Homo sapiens (human)
endochondral ossification	Angiopoietin-1 receptor	Homo sapiens (human)
sprouting angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Angiopoietin-1 receptor	Homo sapiens (human)
cell-cell signaling	Angiopoietin-1 receptor	Homo sapiens (human)
heart development	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of endothelial cell migration	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of establishment or maintenance of cell polarity	Angiopoietin-1 receptor	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of Rac protein signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of Rho protein signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of apoptotic process	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of vascular permeability	Angiopoietin-1 receptor	Homo sapiens (human)
response to peptide hormone	Angiopoietin-1 receptor	Homo sapiens (human)
response to estrogen	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
Tie signaling pathway	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of inflammatory response	Angiopoietin-1 receptor	Homo sapiens (human)
response to cAMP	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of focal adhesion assembly	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
definitive hemopoiesis	Angiopoietin-1 receptor	Homo sapiens (human)
heart trabecula formation	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Angiopoietin-1 receptor	Homo sapiens (human)
glomerulus vasculature development	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of intracellular signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of endothelial cell apoptotic process	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of MAPK cascade	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of kinase activity	Angiopoietin-1 receptor	Homo sapiens (human)
multicellular organism development	Angiopoietin-1 receptor	Homo sapiens (human)
neuron migration	DNA topoisomerase 2-beta	Homo sapiens (human)
DNA topological change	DNA topoisomerase 2-beta	Homo sapiens (human)
axonogenesis	DNA topoisomerase 2-beta	Homo sapiens (human)
B cell differentiation	DNA topoisomerase 2-beta	Homo sapiens (human)
forebrain development	DNA topoisomerase 2-beta	Homo sapiens (human)
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	DNA topoisomerase 2-beta	Homo sapiens (human)
cellular response to hydrogen peroxide	DNA topoisomerase 2-beta	Homo sapiens (human)
cellular response to ATP	DNA topoisomerase 2-beta	Homo sapiens (human)
cellular senescence	DNA topoisomerase 2-beta	Homo sapiens (human)
positive regulation of double-strand break repair via nonhomologous end joining	DNA topoisomerase 2-beta	Homo sapiens (human)
sister chromatid segregation	DNA topoisomerase 2-beta	Homo sapiens (human)
resolution of meiotic recombination intermediates	DNA topoisomerase 2-beta	Homo sapiens (human)
regulation of cell growth	Protein kinase C theta type	Homo sapiens (human)
regulation of DNA-templated transcription	Protein kinase C theta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C theta type	Homo sapiens (human)
membrane protein ectodomain proteolysis	Protein kinase C theta type	Homo sapiens (human)
inflammatory response	Protein kinase C theta type	Homo sapiens (human)
axon guidance	Protein kinase C theta type	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Protein kinase C theta type	Homo sapiens (human)
positive regulation of interleukin-17 production	Protein kinase C theta type	Homo sapiens (human)
positive regulation of interleukin-2 production	Protein kinase C theta type	Homo sapiens (human)
positive regulation of interleukin-4 production	Protein kinase C theta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C theta type	Homo sapiens (human)
CD4-positive, alpha-beta T cell proliferation	Protein kinase C theta type	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Protein kinase C theta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C theta type	Homo sapiens (human)
positive regulation of T cell activation	Protein kinase C theta type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C theta type	Homo sapiens (human)
positive regulation of telomerase activity	Protein kinase C theta type	Homo sapiens (human)
cell chemotaxis	Protein kinase C theta type	Homo sapiens (human)
negative regulation of T cell apoptotic process	Protein kinase C theta type	Homo sapiens (human)
regulation of platelet aggregation	Protein kinase C theta type	Homo sapiens (human)
positive regulation of telomere capping	Protein kinase C theta type	Homo sapiens (human)
positive regulation of T-helper 17 type immune response	Protein kinase C theta type	Homo sapiens (human)
positive regulation of CD4-positive, alpha-beta T cell proliferation	Protein kinase C theta type	Homo sapiens (human)
positive regulation of T-helper 2 cell activation	Protein kinase C theta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C theta type	Homo sapiens (human)
outflow tract septum morphogenesis	Activin receptor type-1	Homo sapiens (human)
branching involved in blood vessel morphogenesis	Activin receptor type-1	Homo sapiens (human)
in utero embryonic development	Activin receptor type-1	Homo sapiens (human)
gastrulation with mouth forming second	Activin receptor type-1	Homo sapiens (human)
mesoderm formation	Activin receptor type-1	Homo sapiens (human)
neural crest cell migration	Activin receptor type-1	Homo sapiens (human)
acute inflammatory response	Activin receptor type-1	Homo sapiens (human)
embryonic heart tube morphogenesis	Activin receptor type-1	Homo sapiens (human)
atrioventricular valve morphogenesis	Activin receptor type-1	Homo sapiens (human)
mitral valve morphogenesis	Activin receptor type-1	Homo sapiens (human)
endocardial cushion formation	Activin receptor type-1	Homo sapiens (human)
endocardial cushion fusion	Activin receptor type-1	Homo sapiens (human)
atrial septum primum morphogenesis	Activin receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Activin receptor type-1	Homo sapiens (human)
germ cell development	Activin receptor type-1	Homo sapiens (human)
determination of left/right symmetry	Activin receptor type-1	Homo sapiens (human)
negative regulation of signal transduction	Activin receptor type-1	Homo sapiens (human)
regulation of ossification	Activin receptor type-1	Homo sapiens (human)
positive regulation of cell migration	Activin receptor type-1	Homo sapiens (human)
positive regulation of bone mineralization	Activin receptor type-1	Homo sapiens (human)
BMP signaling pathway	Activin receptor type-1	Homo sapiens (human)
activin receptor signaling pathway	Activin receptor type-1	Homo sapiens (human)
negative regulation of activin receptor signaling pathway	Activin receptor type-1	Homo sapiens (human)
positive regulation of osteoblast differentiation	Activin receptor type-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Activin receptor type-1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Activin receptor type-1	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Activin receptor type-1	Homo sapiens (human)
smooth muscle cell differentiation	Activin receptor type-1	Homo sapiens (human)
pharyngeal system development	Activin receptor type-1	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Activin receptor type-1	Homo sapiens (human)
ventricular septum morphogenesis	Activin receptor type-1	Homo sapiens (human)
cardiac muscle cell fate commitment	Activin receptor type-1	Homo sapiens (human)
endocardial cushion cell fate commitment	Activin receptor type-1	Homo sapiens (human)
positive regulation of cardiac epithelial to mesenchymal transition	Activin receptor type-1	Homo sapiens (human)
cellular response to BMP stimulus	Activin receptor type-1	Homo sapiens (human)
positive regulation of determination of dorsal identity	Activin receptor type-1	Homo sapiens (human)
negative regulation of G1/S transition of mitotic cell cycle	Activin receptor type-1	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	Activin receptor type-1	Homo sapiens (human)
dorsal/ventral pattern formation	Activin receptor type-1	Homo sapiens (human)
heart development	Activin receptor type-1	Homo sapiens (human)
protein phosphorylation	Activin receptor type-1	Homo sapiens (human)
cellular response to growth factor stimulus	Activin receptor type-1	Homo sapiens (human)
defense response	Macrophage-stimulating protein receptor	Homo sapiens (human)
signal transduction	Macrophage-stimulating protein receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Macrophage-stimulating protein receptor	Homo sapiens (human)
single fertilization	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Macrophage-stimulating protein receptor	Homo sapiens (human)
response to virus	Macrophage-stimulating protein receptor	Homo sapiens (human)
macrophage colony-stimulating factor signaling pathway	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of MAP kinase activity	Macrophage-stimulating protein receptor	Homo sapiens (human)
innate immune response	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Macrophage-stimulating protein receptor	Homo sapiens (human)
nervous system development	Macrophage-stimulating protein receptor	Homo sapiens (human)
cell migration	Macrophage-stimulating protein receptor	Homo sapiens (human)
phagocytosis	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of kinase activity	Macrophage-stimulating protein receptor	Homo sapiens (human)
multicellular organism development	Macrophage-stimulating protein receptor	Homo sapiens (human)
positive regulation of macrophage chemotaxis	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of macrophage proliferation	Focal adhesion kinase 1	Homo sapiens (human)
angiogenesis	Focal adhesion kinase 1	Homo sapiens (human)
placenta development	Focal adhesion kinase 1	Homo sapiens (human)
regulation of protein phosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of protein phosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
heart morphogenesis	Focal adhesion kinase 1	Homo sapiens (human)
signal complex assembly	Focal adhesion kinase 1	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
integrin-mediated signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
axon guidance	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of cell population proliferation	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cell shape	Focal adhesion kinase 1	Homo sapiens (human)
regulation of endothelial cell migration	Focal adhesion kinase 1	Homo sapiens (human)
regulation of epithelial cell migration	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of epithelial cell migration	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of epithelial to mesenchymal transition	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of fibroblast migration	Focal adhesion kinase 1	Homo sapiens (human)
cell migration	Focal adhesion kinase 1	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
negative regulation of cell-cell adhesion	Focal adhesion kinase 1	Homo sapiens (human)
establishment of cell polarity	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of cell migration	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cell adhesion mediated by integrin	Focal adhesion kinase 1	Homo sapiens (human)
detection of muscle stretch	Focal adhesion kinase 1	Homo sapiens (human)
netrin-activated signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cell population proliferation	Focal adhesion kinase 1	Homo sapiens (human)
negative regulation of apoptotic process	Focal adhesion kinase 1	Homo sapiens (human)
regulation of GTPase activity	Focal adhesion kinase 1	Homo sapiens (human)
regulation of osteoblast differentiation	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of protein kinase activity	Focal adhesion kinase 1	Homo sapiens (human)
protein autophosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
ephrin receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
cell motility	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cytoskeleton organization	Focal adhesion kinase 1	Homo sapiens (human)
regulation of focal adhesion assembly	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Focal adhesion kinase 1	Homo sapiens (human)
growth hormone receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of wound healing	Focal adhesion kinase 1	Homo sapiens (human)
regulation of substrate adhesion-dependent cell spreading	Focal adhesion kinase 1	Homo sapiens (human)
positive regulation of ubiquitin-dependent protein catabolic process	Focal adhesion kinase 1	Homo sapiens (human)
negative regulation of anoikis	Focal adhesion kinase 1	Homo sapiens (human)
protein phosphorylation	Focal adhesion kinase 1	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Focal adhesion kinase 1	Homo sapiens (human)
regulation of cell adhesion	Focal adhesion kinase 1	Homo sapiens (human)
microtubule cytoskeleton organization	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Protein kinase C zeta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C zeta type	Homo sapiens (human)
inflammatory response	Protein kinase C zeta type	Homo sapiens (human)
signal transduction	Protein kinase C zeta type	Homo sapiens (human)
cell surface receptor signaling pathway	Protein kinase C zeta type	Homo sapiens (human)
long-term memory	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of cell population proliferation	Protein kinase C zeta type	Homo sapiens (human)
cell migration	Protein kinase C zeta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C zeta type	Homo sapiens (human)
establishment of cell polarity	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-10 production	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-13 production	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-4 production	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-5 production	Protein kinase C zeta type	Homo sapiens (human)
cellular response to insulin stimulus	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of apoptotic process	Protein kinase C zeta type	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of T-helper 2 cell differentiation	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of insulin receptor signaling pathway	Protein kinase C zeta type	Homo sapiens (human)
vesicle transport along microtubule	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of peptidyl-tyrosine phosphorylation	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of protein transport	Protein kinase C zeta type	Homo sapiens (human)
membrane depolarization	Protein kinase C zeta type	Homo sapiens (human)
membrane hyperpolarization	Protein kinase C zeta type	Homo sapiens (human)
long-term synaptic potentiation	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Protein kinase C zeta type	Homo sapiens (human)
protein kinase C signaling	Protein kinase C zeta type	Homo sapiens (human)
protein localization to plasma membrane	Protein kinase C zeta type	Homo sapiens (human)
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	Protein kinase C zeta type	Homo sapiens (human)
neuron projection extension	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of excitatory postsynaptic potential	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of T-helper 2 cell cytokine production	Protein kinase C zeta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C zeta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C delta type	Homo sapiens (human)
apoptotic process	Protein kinase C delta type	Homo sapiens (human)
DNA damage response	Protein kinase C delta type	Homo sapiens (human)
signal transduction	Protein kinase C delta type	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Protein kinase C delta type	Homo sapiens (human)
regulation of signaling receptor activity	Protein kinase C delta type	Homo sapiens (human)
immunoglobulin mediated immune response	Protein kinase C delta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C delta type	Homo sapiens (human)
peptidyl-threonine phosphorylation	Protein kinase C delta type	Homo sapiens (human)
termination of signal transduction	Protein kinase C delta type	Homo sapiens (human)
negative regulation of actin filament polymerization	Protein kinase C delta type	Homo sapiens (human)
positive regulation of endodeoxyribonuclease activity	Protein kinase C delta type	Homo sapiens (human)
negative regulation of protein binding	Protein kinase C delta type	Homo sapiens (human)
activation of protein kinase activity	Protein kinase C delta type	Homo sapiens (human)
positive regulation of superoxide anion generation	Protein kinase C delta type	Homo sapiens (human)
regulation of actin cytoskeleton organization	Protein kinase C delta type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C delta type	Homo sapiens (human)
cellular response to UV	Protein kinase C delta type	Homo sapiens (human)
positive regulation of protein dephosphorylation	Protein kinase C delta type	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Protein kinase C delta type	Homo sapiens (human)
B cell proliferation	Protein kinase C delta type	Homo sapiens (human)
neutrophil activation	Protein kinase C delta type	Homo sapiens (human)
positive regulation of protein import into nucleus	Protein kinase C delta type	Homo sapiens (human)
defense response to bacterium	Protein kinase C delta type	Homo sapiens (human)
negative regulation of MAP kinase activity	Protein kinase C delta type	Homo sapiens (human)
regulation of mRNA stability	Protein kinase C delta type	Homo sapiens (human)
post-translational protein modification	Protein kinase C delta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C delta type	Homo sapiens (human)
negative regulation of inflammatory response	Protein kinase C delta type	Homo sapiens (human)
negative regulation of peptidyl-tyrosine phosphorylation	Protein kinase C delta type	Homo sapiens (human)
protein stabilization	Protein kinase C delta type	Homo sapiens (human)
negative regulation of filopodium assembly	Protein kinase C delta type	Homo sapiens (human)
cell chemotaxis	Protein kinase C delta type	Homo sapiens (human)
cellular response to hydrogen peroxide	Protein kinase C delta type	Homo sapiens (human)
cellular response to hydroperoxide	Protein kinase C delta type	Homo sapiens (human)
negative regulation of platelet aggregation	Protein kinase C delta type	Homo sapiens (human)
cellular senescence	Protein kinase C delta type	Homo sapiens (human)
positive regulation of phospholipid scramblase activity	Protein kinase C delta type	Homo sapiens (human)
cellular response to angiotensin	Protein kinase C delta type	Homo sapiens (human)
regulation of ceramide biosynthetic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of ceramide biosynthetic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of glucosylceramide catabolic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of sphingomyelin catabolic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Protein kinase C delta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C delta type	Homo sapiens (human)
neutrophil homeostasis	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of type III hypersensitivity	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of type I hypersensitivity	Tyrosine-protein kinase BTK	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase BTK	Homo sapiens (human)
B cell affinity maturation	Tyrosine-protein kinase BTK	Homo sapiens (human)
histamine secretion by mast cell	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of immunoglobulin production	Tyrosine-protein kinase BTK	Homo sapiens (human)
regulation of B cell cytokine production	Tyrosine-protein kinase BTK	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
regulation of B cell apoptotic process	Tyrosine-protein kinase BTK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase BTK	Homo sapiens (human)
mesoderm development	Tyrosine-protein kinase BTK	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase BTK	Homo sapiens (human)
calcium-mediated signaling	Tyrosine-protein kinase BTK	Homo sapiens (human)
proteoglycan catabolic process	Tyrosine-protein kinase BTK	Homo sapiens (human)
negative regulation of B cell proliferation	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of B cell proliferation	Tyrosine-protein kinase BTK	Homo sapiens (human)
response to lipopolysaccharide	Tyrosine-protein kinase BTK	Homo sapiens (human)
negative regulation of interleukin-10 production	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of interleukin-6 production	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of tumor necrosis factor production	Tyrosine-protein kinase BTK	Homo sapiens (human)
cellular response to reactive oxygen species	Tyrosine-protein kinase BTK	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase BTK	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
B cell activation	Tyrosine-protein kinase BTK	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of B cell differentiation	Tyrosine-protein kinase BTK	Homo sapiens (human)
cell maturation	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of phagocytosis	Tyrosine-protein kinase BTK	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Tyrosine-protein kinase BTK	Homo sapiens (human)
monocyte proliferation	Tyrosine-protein kinase BTK	Homo sapiens (human)
cellular response to molecule of fungal origin	Tyrosine-protein kinase BTK	Homo sapiens (human)
apoptotic signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
cellular response to interleukin-7	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of interleukin-17A production	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	Tyrosine-protein kinase BTK	Homo sapiens (human)
positive regulation of synoviocyte proliferation	Tyrosine-protein kinase BTK	Homo sapiens (human)
eosinophil homeostasis	Tyrosine-protein kinase BTK	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase BTK	Homo sapiens (human)
endocytosis	Activated CDC42 kinase 1	Homo sapiens (human)
cell surface receptor signaling pathway	Activated CDC42 kinase 1	Homo sapiens (human)
small GTPase-mediated signal transduction	Activated CDC42 kinase 1	Homo sapiens (human)
phosphorylation	Activated CDC42 kinase 1	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Activated CDC42 kinase 1	Homo sapiens (human)
regulation of clathrin-dependent endocytosis	Activated CDC42 kinase 1	Homo sapiens (human)
protein phosphorylation	Activated CDC42 kinase 1	Homo sapiens (human)
regulation of cell growth	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
regulation of cell-matrix adhesion	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
cell adhesion	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
embryo implantation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
lactation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
cell population proliferation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
negative regulation of cell population proliferation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
regulation of extracellular matrix disassembly	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
smooth muscle cell migration	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
collagen-activated tyrosine kinase receptor signaling pathway	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
ear development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
wound healing, spreading of cells	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
protein autophosphorylation	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
branching involved in mammary gland duct morphogenesis	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
mammary gland alveolus development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
smooth muscle cell-matrix adhesion	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
axon development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
neuron projection extension	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
multicellular organism development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
positive regulation of kinase activity	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
positive regulation of neuron projection development	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of heart rate by hormone	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of membrane potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
potassium ion homeostasis	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
cardiac muscle contraction	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of membrane repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of ventricular cardiac muscle cell membrane repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
cellular response to xenobiotic stimulus	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
potassium ion transmembrane transport	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
ventricular cardiac muscle cell action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane depolarization during action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane repolarization during action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane repolarization during cardiac muscle cell action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
potassium ion export across plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
membrane repolarization during ventricular cardiac muscle cell action potential	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
regulation of potassium ion transmembrane transport	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
negative regulation of potassium ion transmembrane transport	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
positive regulation of potassium ion transmembrane transport	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
negative regulation of potassium ion export across plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
potassium ion import across plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
vesicle targeting	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
immune response	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
innate immune response	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
positive regulation of JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
cell morphogenesis	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of protein phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of protein binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase 4	Homo sapiens (human)
branching involved in blood vessel morphogenesis	Serine/threonine-protein kinase 4	Homo sapiens (human)
neural tube formation	Serine/threonine-protein kinase 4	Homo sapiens (human)
endocardium development	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein import into nucleus	Serine/threonine-protein kinase 4	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase 4	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase 4	Homo sapiens (human)
central nervous system development	Serine/threonine-protein kinase 4	Homo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptors	Serine/threonine-protein kinase 4	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase 4	Homo sapiens (human)
keratinocyte differentiation	Serine/threonine-protein kinase 4	Homo sapiens (human)
organ growth	Serine/threonine-protein kinase 4	Homo sapiens (human)
hippo signaling	Serine/threonine-protein kinase 4	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of apoptotic process	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of fat cell differentiation	Serine/threonine-protein kinase 4	Homo sapiens (human)
negative regulation of organ growth	Serine/threonine-protein kinase 4	Homo sapiens (human)
epithelial cell proliferation	Serine/threonine-protein kinase 4	Homo sapiens (human)
negative regulation of epithelial cell proliferation	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein tetramerization	Serine/threonine-protein kinase 4	Homo sapiens (human)
canonical Wnt signaling pathway	Serine/threonine-protein kinase 4	Homo sapiens (human)
primitive hemopoiesis	Serine/threonine-protein kinase 4	Homo sapiens (human)
cell differentiation involved in embryonic placenta development	Serine/threonine-protein kinase 4	Homo sapiens (human)
regulation of cell differentiation involved in embryonic placenta development	Serine/threonine-protein kinase 4	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Serine/threonine-protein kinase 4	Homo sapiens (human)
hepatocyte apoptotic process	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of hepatocyte apoptotic process	Serine/threonine-protein kinase 4	Homo sapiens (human)
positive regulation of substrate-dependent cell migration, cell attachment to substrate	Serine/threonine-protein kinase 4	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase 4	Homo sapiens (human)
lipid droplet disassembly	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to hypoxia	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
glucose metabolic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
chromatin remodeling	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein phosphorylation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
fatty acid biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cholesterol biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
autophagy	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
signal transduction	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of cell population proliferation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
lipid biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to UV	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cold acclimation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to gamma radiation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of autophagy	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of gene expression	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of gene expression	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
bile acid and bile salt transport	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
Wnt signaling pathway	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
fatty acid oxidation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to caffeine	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to nutrient levels	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of TOR signaling	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of peptidyl-serine phosphorylation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to oxidative stress	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
bile acid signaling pathway	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to glucose starvation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
glucose homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of circadian rhythm	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of apoptotic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
response to estrogen	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of cholesterol biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of glycolytic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of glucosylceramide biosynthetic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
rhythmic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of skeletal muscle tissue development	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of lipid catabolic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
fatty acid homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of vesicle-mediated transport	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
motor behavior	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
CAMKK-AMPK signaling cascade	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of stress granule assembly	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
neuron cellular homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to hydrogen peroxide	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to calcium ion	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to glucose stimulus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to ethanol	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to prostaglandin E stimulus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to organonitrogen compound	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to hypoxia	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cellular response to xenobiotic stimulus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
energy homeostasis	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
regulation of bile acid secretion	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of mitochondrial transcription	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of protein localization	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of hepatocyte apoptotic process	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of protein targeting to mitochondrion	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of adipose tissue development	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of TORC1 signaling	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of tubulin deacetylation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein localization to lipid droplet	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
positive regulation of peptidyl-lysine acetylation	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
MAPK cascade	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
signal transduction	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
heart development	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of cell growth	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of NF-kappaB transcription factor activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of interleukin-8 production	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of heterotypic cell-cell adhesion	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of smooth muscle cell apoptotic process	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of MAP kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
insulin-like growth factor receptor signaling pathway	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of epithelial cell proliferation	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
positive regulation of protein metabolic process	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of response to cytokine stimulus	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
ERK5 cascade	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
cellular response to growth factor stimulus	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
cellular response to laminar fluid shear stress	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of cell migration involved in sprouting angiogenesis	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of chemokine (C-X-C motif) ligand 2 production	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase 7	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 7	Homo sapiens (human)
adenylate cyclase-activating G protein-coupled receptor signaling pathway	Mitogen-activated protein kinase 7	Homo sapiens (human)
cell differentiation	Mitogen-activated protein kinase 7	Homo sapiens (human)
calcineurin-NFAT signaling cascade	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of heterotypic cell-cell adhesion	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of smooth muscle cell apoptotic process	Mitogen-activated protein kinase 7	Homo sapiens (human)
regulation of angiogenesis	Mitogen-activated protein kinase 7	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of inflammatory response	Mitogen-activated protein kinase 7	Homo sapiens (human)
positive regulation of protein metabolic process	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of response to cytokine stimulus	Mitogen-activated protein kinase 7	Homo sapiens (human)
cellular response to hydrogen peroxide	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of calcineurin-NFAT signaling cascade	Mitogen-activated protein kinase 7	Homo sapiens (human)
cellular response to growth factor stimulus	Mitogen-activated protein kinase 7	Homo sapiens (human)
cellular response to laminar fluid shear stress	Mitogen-activated protein kinase 7	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Mitogen-activated protein kinase 7	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Mitogen-activated protein kinase 7	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cardiac muscle hypertrophy	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
negative regulation of protein kinase activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
adherens junction assembly	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
negative regulation of apoptotic process	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
regulation of cytoskeleton organization	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
negative regulation of stress fiber assembly	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
dendritic spine development	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
bicellular tight junction assembly	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cellular response to organic cyclic compound	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein localization to cell-cell junction	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
regulation of axonogenesis	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
positive regulation of protein binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
neural tube formation	Serine/threonine-protein kinase 3	Homo sapiens (human)
endocardium development	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein import into nucleus	Serine/threonine-protein kinase 3	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase 3	Homo sapiens (human)
JNK cascade	Serine/threonine-protein kinase 3	Homo sapiens (human)
central nervous system development	Serine/threonine-protein kinase 3	Homo sapiens (human)
extrinsic apoptotic signaling pathway via death domain receptors	Serine/threonine-protein kinase 3	Homo sapiens (human)
organ growth	Serine/threonine-protein kinase 3	Homo sapiens (human)
hippo signaling	Serine/threonine-protein kinase 3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of apoptotic process	Serine/threonine-protein kinase 3	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of fat cell differentiation	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of JNK cascade	Serine/threonine-protein kinase 3	Homo sapiens (human)
negative regulation of organ growth	Serine/threonine-protein kinase 3	Homo sapiens (human)
epithelial cell proliferation	Serine/threonine-protein kinase 3	Homo sapiens (human)
negative regulation of epithelial cell proliferation	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein tetramerization	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase 3	Homo sapiens (human)
canonical Wnt signaling pathway	Serine/threonine-protein kinase 3	Homo sapiens (human)
primitive hemopoiesis	Serine/threonine-protein kinase 3	Homo sapiens (human)
cell differentiation involved in embryonic placenta development	Serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of cell differentiation involved in embryonic placenta development	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein localization to centrosome	Serine/threonine-protein kinase 3	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Serine/threonine-protein kinase 3	Homo sapiens (human)
hepatocyte apoptotic process	Serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase 3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
cellular response to mechanical stimulus	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
cell morphogenesis	Integrin-linked protein kinase	Homo sapiens (human)
integrin-mediated signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
branching involved in ureteric bud morphogenesis	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of protein phosphorylation	Integrin-linked protein kinase	Homo sapiens (human)
outflow tract morphogenesis	Integrin-linked protein kinase	Homo sapiens (human)
protein phosphorylation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of cell population proliferation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of signal transduction	Integrin-linked protein kinase	Homo sapiens (human)
fibroblast migration	Integrin-linked protein kinase	Homo sapiens (human)
nerve development	Integrin-linked protein kinase	Homo sapiens (human)
myelination in peripheral nervous system	Integrin-linked protein kinase	Homo sapiens (human)
cell projection organization	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of BMP signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of phosphorylation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Integrin-linked protein kinase	Homo sapiens (human)
phosphatidylinositol 3-kinase/protein kinase B signal transduction	Integrin-linked protein kinase	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of osteoblast differentiation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of DNA-templated transcription	Integrin-linked protein kinase	Homo sapiens (human)
neural precursor cell proliferation	Integrin-linked protein kinase	Homo sapiens (human)
platelet aggregation	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
positive regulation of substrate adhesion-dependent cell spreading	Integrin-linked protein kinase	Homo sapiens (human)
negative regulation of neural precursor cell proliferation	Integrin-linked protein kinase	Homo sapiens (human)
cell-matrix adhesion	Integrin-linked protein kinase	Homo sapiens (human)
integrin-mediated signaling pathway	Integrin-linked protein kinase	Homo sapiens (human)
epithelial to mesenchymal transition	Rho-associated protein kinase 1	Homo sapiens (human)
aortic valve morphogenesis	Rho-associated protein kinase 1	Homo sapiens (human)
apical constriction	Rho-associated protein kinase 1	Homo sapiens (human)
protein phosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
smooth muscle contraction	Rho-associated protein kinase 1	Homo sapiens (human)
leukocyte cell-cell adhesion	Rho-associated protein kinase 1	Homo sapiens (human)
signal transduction	Rho-associated protein kinase 1	Homo sapiens (human)
canonical NF-kappaB signal transduction	Rho-associated protein kinase 1	Homo sapiens (human)
Rho protein signal transduction	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of autophagy	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of cardiac muscle hypertrophy	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of gene expression	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of phosphatase activity	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of angiogenesis	Rho-associated protein kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
membrane to membrane docking	Rho-associated protein kinase 1	Homo sapiens (human)
actin cytoskeleton organization	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of cell adhesion	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of cell migration	Rho-associated protein kinase 1	Homo sapiens (human)
cortical actin cytoskeleton organization	Rho-associated protein kinase 1	Homo sapiens (human)
neuron projection development	Rho-associated protein kinase 1	Homo sapiens (human)
bleb assembly	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of protein binding	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of actin cytoskeleton organization	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of dephosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of myosin-light-chain-phosphatase activity	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of phosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of MAPK cascade	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of keratinocyte differentiation	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of neuron differentiation	Rho-associated protein kinase 1	Homo sapiens (human)
leukocyte migration	Rho-associated protein kinase 1	Homo sapiens (human)
leukocyte tethering or rolling	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of membrane protein ectodomain proteolysis	Rho-associated protein kinase 1	Homo sapiens (human)
myoblast migration	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of stress fiber assembly	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of focal adhesion assembly	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of focal adhesion assembly	Rho-associated protein kinase 1	Homo sapiens (human)
mRNA destabilization	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of biomineral tissue development	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Rho-associated protein kinase 1	Homo sapiens (human)
response to transforming growth factor beta	Rho-associated protein kinase 1	Homo sapiens (human)
protein localization to plasma membrane	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of synapse maturation	Rho-associated protein kinase 1	Homo sapiens (human)
podocyte cell migration	Rho-associated protein kinase 1	Homo sapiens (human)
motor neuron apoptotic process	Rho-associated protein kinase 1	Homo sapiens (human)
blood vessel diameter maintenance	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of angiotensin-activated signaling pathway	Rho-associated protein kinase 1	Homo sapiens (human)
neuron projection arborization	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of amyloid-beta clearance	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of synaptic vesicle endocytosis	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of amyloid-beta formation	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of amyloid precursor protein catabolic process	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of establishment of endothelial barrier	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of bicellular tight junction assembly	Rho-associated protein kinase 1	Homo sapiens (human)
positive regulation of connective tissue replacement	Rho-associated protein kinase 1	Homo sapiens (human)
response to angiotensin	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of establishment of cell polarity	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of cell motility	Rho-associated protein kinase 1	Homo sapiens (human)
negative regulation of motor neuron apoptotic process	Rho-associated protein kinase 1	Homo sapiens (human)
regulation of cell junction assembly	Rho-associated protein kinase 1	Homo sapiens (human)
mitotic cytokinesis	Rho-associated protein kinase 1	Homo sapiens (human)
embryonic morphogenesis	Rho-associated protein kinase 1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Rho-associated protein kinase 1	Homo sapiens (human)
actomyosin structure organization	Rho-associated protein kinase 1	Homo sapiens (human)
protein phosphorylation	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
protein autophosphorylation	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
nervous system development	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
regulation of neuron projection development	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
regulation of skeletal muscle adaptation	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
insulin secretion	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
cell differentiation	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
regulation of calcium ion transport	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
regulation of cell growth	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of the force of heart contraction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of membrane depolarization	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein phosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of heart contraction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
positive regulation of cardiac muscle hypertrophy	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cell communication by electrical coupling	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic process	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
peptidyl-serine phosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
peptidyl-threonine phosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
endoplasmic reticulum calcium ion homeostasis	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein autophosphorylation	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
relaxation of cardiac muscle	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of ryanodine-sensitive calcium-release channel activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cellular localization	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cellular response to calcium ion	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cardiac muscle cell contraction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cardiac muscle cell action potential	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cardiac muscle cell action potential involved in regulation of contraction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of cell communication by electrical coupling involved in cardiac conduction	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of relaxation of cardiac muscle	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
negative regulation of sodium ion transmembrane transport	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
negative regulation of sodium ion transmembrane transporter activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
chromatin remodeling	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nervous system development	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
circadian rhythm	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-serine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-threonine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
negative regulation of microtubule polymerization	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
positive regulation of RNA splicing	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
amyloid-beta formation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-serine autophosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
negative regulation of DNA damage response, signal transduction by p53 class mediator	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein autophosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
negative regulation of mRNA splicing, via spliceosome	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
negative regulation of DNA methylation-dependent heterochromatin formation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
positive regulation of protein deacetylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Activin receptor type-2B	Homo sapiens (human)
gastrulation with mouth forming second	Activin receptor type-2B	Homo sapiens (human)
kidney development	Activin receptor type-2B	Homo sapiens (human)
lymphangiogenesis	Activin receptor type-2B	Homo sapiens (human)
blood vessel remodeling	Activin receptor type-2B	Homo sapiens (human)
regulation of DNA-templated transcription	Activin receptor type-2B	Homo sapiens (human)
signal transduction	Activin receptor type-2B	Homo sapiens (human)
cell surface receptor protein serine/threonine kinase signaling pathway	Activin receptor type-2B	Homo sapiens (human)
determination of left/right symmetry	Activin receptor type-2B	Homo sapiens (human)
mesoderm development	Activin receptor type-2B	Homo sapiens (human)
heart development	Activin receptor type-2B	Homo sapiens (human)
response to glucose	Activin receptor type-2B	Homo sapiens (human)
post-embryonic development	Activin receptor type-2B	Homo sapiens (human)
anterior/posterior pattern specification	Activin receptor type-2B	Homo sapiens (human)
insulin secretion	Activin receptor type-2B	Homo sapiens (human)
lung development	Activin receptor type-2B	Homo sapiens (human)
positive regulation of bone mineralization	Activin receptor type-2B	Homo sapiens (human)
BMP signaling pathway	Activin receptor type-2B	Homo sapiens (human)
pancreas development	Activin receptor type-2B	Homo sapiens (human)
activin receptor signaling pathway	Activin receptor type-2B	Homo sapiens (human)
positive regulation of activin receptor signaling pathway	Activin receptor type-2B	Homo sapiens (human)
organ growth	Activin receptor type-2B	Homo sapiens (human)
odontogenesis of dentin-containing tooth	Activin receptor type-2B	Homo sapiens (human)
positive regulation of osteoblast differentiation	Activin receptor type-2B	Homo sapiens (human)
embryonic foregut morphogenesis	Activin receptor type-2B	Homo sapiens (human)
skeletal system morphogenesis	Activin receptor type-2B	Homo sapiens (human)
roof of mouth development	Activin receptor type-2B	Homo sapiens (human)
lymphatic endothelial cell differentiation	Activin receptor type-2B	Homo sapiens (human)
artery development	Activin receptor type-2B	Homo sapiens (human)
venous blood vessel development	Activin receptor type-2B	Homo sapiens (human)
retina vasculature development in camera-type eye	Activin receptor type-2B	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Activin receptor type-2B	Homo sapiens (human)
cellular response to growth factor stimulus	Activin receptor type-2B	Homo sapiens (human)
protein phosphorylation	Activin receptor type-2B	Homo sapiens (human)
outflow tract septum morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
atrioventricular valve morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cardiac muscle tissue development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
pharyngeal arch artery morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of gene expression	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
osteoblast differentiation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
mesoderm formation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
maternal placenta development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
endothelial cell proliferation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
lymphangiogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
blood vessel remodeling	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
chondrocyte development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of systemic arterial blood pressure	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
outflow tract morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
aortic valve development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
pulmonary valve development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
mitral valve morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
tricuspid valve morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
endocardial cushion development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of cell proliferation involved in heart valve morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cell surface receptor protein serine/threonine kinase signaling pathway	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cellular response to starvation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
anterior/posterior pattern specification	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of epithelial cell migration	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
regulation of lung blood pressure	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
proteoglycan biosynthetic process	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of cell growth	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of bone mineralization	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
BMP signaling pathway	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
activin receptor signaling pathway	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
regulation of cell population proliferation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of osteoblast differentiation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of ossification	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of vasoconstriction	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
lung alveolus development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of smooth muscle cell proliferation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of axon extension involved in axon guidance	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of muscle cell differentiation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
limb development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
endochondral bone morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of SMAD protein signal transduction	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
ventricular septum morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
atrial septum morphogenesis	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
lung vasculature development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
lymphatic endothelial cell differentiation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
artery development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
venous blood vessel development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
positive regulation of cartilage development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
retina vasculature development in camera-type eye	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cellular response to BMP stimulus	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
endothelial cell apoptotic process	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
negative regulation of chondrocyte proliferation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
semi-lunar valve development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cellular response to growth factor stimulus	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
blood vessel development	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
protein phosphorylation	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
protein phosphorylation	Protein-tyrosine kinase 6	Homo sapiens (human)
tyrosine phosphorylation of STAT protein	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of neuron projection development	Protein-tyrosine kinase 6	Homo sapiens (human)
cell migration	Protein-tyrosine kinase 6	Homo sapiens (human)
ERBB2 signaling pathway	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of DNA replication	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of epidermal growth factor receptor signaling pathway	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of cell cycle	Protein-tyrosine kinase 6	Homo sapiens (human)
negative regulation of growth	Protein-tyrosine kinase 6	Homo sapiens (human)
protein autophosphorylation	Protein-tyrosine kinase 6	Homo sapiens (human)
intestinal epithelial cell differentiation	Protein-tyrosine kinase 6	Homo sapiens (human)
negative regulation of protein tyrosine kinase activity	Protein-tyrosine kinase 6	Homo sapiens (human)
cellular response to retinoic acid	Protein-tyrosine kinase 6	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Protein-tyrosine kinase 6	Homo sapiens (human)
innate immune response	Protein-tyrosine kinase 6	Homo sapiens (human)
cell differentiation	Protein-tyrosine kinase 6	Homo sapiens (human)
positive regulation of receptor signaling pathway via JAK-STAT	Protein-tyrosine kinase 6	Homo sapiens (human)
protein phosphorylation	cGMP-dependent protein kinase 1	Homo sapiens (human)
neuron migration	cGMP-dependent protein kinase 1	Homo sapiens (human)
signal transduction	cGMP-dependent protein kinase 1	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	cGMP-dependent protein kinase 1	Homo sapiens (human)
spermatid development	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of inositol phosphate biosynthetic process	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of glutamate secretion	cGMP-dependent protein kinase 1	Homo sapiens (human)
dendrite development	cGMP-dependent protein kinase 1	Homo sapiens (human)
cGMP-mediated signaling	cGMP-dependent protein kinase 1	Homo sapiens (human)
cerebellum development	cGMP-dependent protein kinase 1	Homo sapiens (human)
actin cytoskeleton organization	cGMP-dependent protein kinase 1	Homo sapiens (human)
forebrain development	cGMP-dependent protein kinase 1	Homo sapiens (human)
positive regulation of circadian rhythm	cGMP-dependent protein kinase 1	Homo sapiens (human)
regulation of GTPase activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
collateral sprouting	cGMP-dependent protein kinase 1	Homo sapiens (human)
relaxation of vascular associated smooth muscle	cGMP-dependent protein kinase 1	Homo sapiens (human)
cell growth involved in cardiac muscle cell development	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of platelet aggregation	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of vascular associated smooth muscle cell proliferation	cGMP-dependent protein kinase 1	Homo sapiens (human)
negative regulation of vascular associated smooth muscle cell migration	cGMP-dependent protein kinase 1	Homo sapiens (human)
regulation of testosterone biosynthetic process	cGMP-dependent protein kinase 1	Homo sapiens (human)
protein kinase A signaling	cGMP-dependent protein kinase 1	Homo sapiens (human)
alternative mRNA splicing, via spliceosome	Cyclin-dependent kinase 13	Homo sapiens (human)
regulation of signal transduction	Cyclin-dependent kinase 13	Homo sapiens (human)
hemopoiesis	Cyclin-dependent kinase 13	Homo sapiens (human)
positive regulation of transcription elongation by RNA polymerase II	Cyclin-dependent kinase 13	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 13	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 13	Homo sapiens (human)
negative regulation of stem cell differentiation	Cyclin-dependent kinase 13	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 13	Homo sapiens (human)
immune response	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
gene expression	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of lipid storage	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of type I interferon production	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
response to interferon-beta	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
regulation of protein-containing complex assembly	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
mRNA stabilization	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
defense response to virus	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
type I interferon-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of type I interferon-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
interleukin-17-mediated signaling pathway	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
cellular response to virus	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
peptidyl-serine phosphorylation	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
MAPK cascade	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
oocyte maturation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to hypoxia	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
sprouting angiogenesis	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
adaptive immune response	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
marginal zone B cell differentiation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to ischemia	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein phosphorylation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
apoptotic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cellular defense response	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
signal transduction	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cell surface receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
signal complex assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cytosolic calcium ion concentration	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
integrin-mediated signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cell population proliferation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of cell population proliferation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of cell shape	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to xenobiotic stimulus	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to mechanical stimulus	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to hormone	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to glucose	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of endothelial cell migration	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of muscle cell apoptotic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of macrophage chemotaxis	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of neuron projection development	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
glial cell proliferation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of cell adhesion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cell growth	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of cell migration	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of bone mineralization	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of actin filament polymerization	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cortical cytoskeleton organization	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
neuron projection development	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of actin cytoskeleton organization	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
ionotropic glutamate receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to immobilization stress	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to cocaine	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to hydrogen peroxide	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
activation of Janus kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of apoptotic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
stress fiber assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to cation stress	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of potassium ion transport	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of neuron apoptotic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
blood vessel endothelial cell migration	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
bone resorption	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to ethanol	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
negative regulation of myeloid cell differentiation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of translation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of angiogenesis	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of protein kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of JNK cascade	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein autophosphorylation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
focal adhesion assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of synaptic plasticity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to cAMP	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
response to calcium ion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of synaptic transmission, glutamatergic	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
long-term synaptic potentiation	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
long-term synaptic depression	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein-containing complex assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
chemokine-mediated signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cellular response to retinoic acid	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cellular response to fluid shear stress	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
endothelin receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of postsynaptic density assembly	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
postsynaptic modulation of chemical synaptic transmission	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
regulation of ubiquitin-dependent protein catabolic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of ubiquitin-dependent protein catabolic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of excitatory postsynaptic potential	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of B cell chemotaxis	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
positive regulation of DNA biosynthetic process	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
apoptotic process	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
cell population proliferation	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
hemopoiesis	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
positive regulation of apoptotic process	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
protein autophosphorylation	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
neural precursor cell proliferation	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
protein phosphorylation	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
mitotic sister chromatid segregation	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
DNA repair	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
sister chromatid cohesion	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mitotic sister chromatid cohesion	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
response to radiation	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
establishment of mitotic sister chromatid cohesion	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
establishment of meiotic sister chromatid cohesion	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
somatic stem cell population maintenance	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
cell division	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
meiotic cell cycle	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
response to DNA damage checkpoint signaling	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mitotic spindle assembly	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
double-strand break repair via homologous recombination	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
chromatin remodeling	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
negative regulation of gene expression	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
regulation of cell fate specification	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
negative regulation of DNA-templated transcription	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
positive regulation of DNA-templated transcription	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
regulation of synapse assembly	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
terminal button organization	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
regulation of stem cell differentiation	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
very long-chain fatty acid metabolic process	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
generation of precursor metabolites and energy	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
lipid metabolic process	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
prostaglandin metabolic process	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
spermatogenesis	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
fatty acid catabolic process	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
fatty acid oxidation	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA oxidase	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
hydrogen peroxide biosynthetic process	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
very long-chain fatty acid beta-oxidation	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
lipid homeostasis	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
positive regulation of protein phosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
brain development	Ephrin type-A receptor 7	Homo sapiens (human)
phosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of cell-cell adhesion	Ephrin type-A receptor 7	Homo sapiens (human)
retinal ganglion cell axon guidance	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of protein autophosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of cysteine-type endopeptidase activity involved in apoptotic process	Ephrin type-A receptor 7	Homo sapiens (human)
positive regulation of neuron apoptotic process	Ephrin type-A receptor 7	Homo sapiens (human)
ephrin receptor signaling pathway	Ephrin type-A receptor 7	Homo sapiens (human)
negative regulation of collateral sprouting	Ephrin type-A receptor 7	Homo sapiens (human)
branching morphogenesis of a nerve	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of peptidyl-tyrosine phosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
modulation of chemical synaptic transmission	Ephrin type-A receptor 7	Homo sapiens (human)
negative chemotaxis	Ephrin type-A receptor 7	Homo sapiens (human)
neuron apoptotic process	Ephrin type-A receptor 7	Homo sapiens (human)
negative regulation of synapse assembly	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Ephrin type-A receptor 7	Homo sapiens (human)
nephric duct morphogenesis	Ephrin type-A receptor 7	Homo sapiens (human)
regulation of postsynapse organization	Ephrin type-A receptor 7	Homo sapiens (human)
axon guidance	Ephrin type-A receptor 7	Homo sapiens (human)
protein phosphorylation	Ephrin type-A receptor 7	Homo sapiens (human)
cholesterol biosynthetic process	Delta(24)-sterol reductase	Homo sapiens (human)
cholesterol biosynthetic process	Delta(24)-sterol reductase	Homo sapiens (human)
Ras protein signal transduction	Delta(24)-sterol reductase	Homo sapiens (human)
protein localization	Delta(24)-sterol reductase	Homo sapiens (human)
negative regulation of cell population proliferation	Delta(24)-sterol reductase	Homo sapiens (human)
response to hormone	Delta(24)-sterol reductase	Homo sapiens (human)
tissue development	Delta(24)-sterol reductase	Homo sapiens (human)
male genitalia development	Delta(24)-sterol reductase	Homo sapiens (human)
plasminogen activation	Delta(24)-sterol reductase	Homo sapiens (human)
cholesterol biosynthetic process via desmosterol	Delta(24)-sterol reductase	Homo sapiens (human)
cholesterol biosynthetic process via lathosterol	Delta(24)-sterol reductase	Homo sapiens (human)
amyloid precursor protein catabolic process	Delta(24)-sterol reductase	Homo sapiens (human)
skin development	Delta(24)-sterol reductase	Homo sapiens (human)
membrane organization	Delta(24)-sterol reductase	Homo sapiens (human)
steroid metabolic process	Delta(24)-sterol reductase	Homo sapiens (human)
protein phosphorylation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
signal transduction	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
chemical synaptic transmission	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of cell growth	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
negative regulation of TOR signaling	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
intracellular signal transduction	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
negative regulation of apoptotic process	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
regulation of translation in response to stress	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of cell differentiation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
hepatocyte proliferation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of hepatic stellate cell activation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein phosphorylation	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
smooth muscle contraction	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
tonic smooth muscle contraction	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
positive regulation of cell migration	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
bleb assembly	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
positive regulation of calcium ion transport	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
aorta smooth muscle tissue morphogenesis	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cellular hypotonic response	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
positive regulation of wound healing	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
positive regulation of erythrocyte differentiation	Mitogen-activated protein kinase 11	Homo sapiens (human)
osteoblast differentiation	Mitogen-activated protein kinase 11	Homo sapiens (human)
positive regulation of gene expression	Mitogen-activated protein kinase 11	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Mitogen-activated protein kinase 11	Homo sapiens (human)
positive regulation of interleukin-12 production	Mitogen-activated protein kinase 11	Homo sapiens (human)
p38MAPK cascade	Mitogen-activated protein kinase 11	Homo sapiens (human)
positive regulation of muscle cell differentiation	Mitogen-activated protein kinase 11	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 11	Homo sapiens (human)
cardiac muscle cell proliferation	Mitogen-activated protein kinase 11	Homo sapiens (human)
negative regulation of cardiac muscle cell proliferation	Mitogen-activated protein kinase 11	Homo sapiens (human)
bone development	Mitogen-activated protein kinase 11	Homo sapiens (human)
cellular response to interleukin-1	Mitogen-activated protein kinase 11	Homo sapiens (human)
cellular response to UV-B	Mitogen-activated protein kinase 11	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 11	Homo sapiens (human)
cellular response to virus	Mitogen-activated protein kinase 11	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 11	Homo sapiens (human)
G1 to G0 transition	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of cell growth	Serine/threonine-protein kinase STK11	Homo sapiens (human)
tissue homeostasis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
vasculature development	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein dephosphorylation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
autophagy	Serine/threonine-protein kinase STK11	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase STK11	Homo sapiens (human)
spermatogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
axonogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of cell population proliferation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to ionizing radiation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
establishment of cell polarity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of cell growth	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of transforming growth factor beta receptor signaling pathway	Serine/threonine-protein kinase STK11	Homo sapiens (human)
activation of protein kinase activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to glucagon	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to lipid	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein localization to nucleus	Serine/threonine-protein kinase STK11	Homo sapiens (human)
glucose homeostasis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
anoikis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive thymic T cell selection	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of gluconeogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of dendrite morphogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of axonogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
T cell receptor signaling pathway	Serine/threonine-protein kinase STK11	Homo sapiens (human)
Golgi localization	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of cell cycle	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase STK11	Homo sapiens (human)
epithelial cell proliferation involved in prostate gland development	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of epithelial cell proliferation involved in prostate gland development	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cellular response to UV-B	Serine/threonine-protein kinase STK11	Homo sapiens (human)
intrinsic apoptotic signaling pathway by p53 class mediator	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Serine/threonine-protein kinase STK11	Homo sapiens (human)
response to thyroid hormone	Serine/threonine-protein kinase STK11	Homo sapiens (human)
dendrite extension	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of protein localization to nucleus	Serine/threonine-protein kinase STK11	Homo sapiens (human)
positive regulation of vesicle transport along microtubule	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Serine/threonine-protein kinase STK11	Homo sapiens (human)
negative regulation of TORC1 signaling	Serine/threonine-protein kinase STK11	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase STK11	Homo sapiens (human)
regulation of Wnt signaling pathway	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cytoskeleton organization	Coiled-coil domain-containing protein 6	Homo sapiens (human)
biological_process	Coiled-coil domain-containing protein 6	Homo sapiens (human)
B cell homeostasis	Serine/threonine-protein kinase N1	Homo sapiens (human)
B cell apoptotic process	Serine/threonine-protein kinase N1	Homo sapiens (human)
negative regulation of protein phosphorylation	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of germinal center formation	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of immunoglobulin production	Serine/threonine-protein kinase N1	Homo sapiens (human)
renal system process	Serine/threonine-protein kinase N1	Homo sapiens (human)
chromatin remodeling	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase N1	Homo sapiens (human)
hyperosmotic response	Serine/threonine-protein kinase N1	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase N1	Homo sapiens (human)
epithelial cell migration	Serine/threonine-protein kinase N1	Homo sapiens (human)
negative regulation of B cell proliferation	Serine/threonine-protein kinase N1	Homo sapiens (human)
post-translational protein modification	Serine/threonine-protein kinase N1	Homo sapiens (human)
positive regulation of DNA-templated transcription	Serine/threonine-protein kinase N1	Homo sapiens (human)
spleen development	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of androgen receptor signaling pathway	Serine/threonine-protein kinase N1	Homo sapiens (human)
regulation of cell motility	Serine/threonine-protein kinase N1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase N1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase N2	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase N2	Homo sapiens (human)
cell adhesion	Serine/threonine-protein kinase N2	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase N2	Homo sapiens (human)
epithelial cell migration	Serine/threonine-protein kinase N2	Homo sapiens (human)
cell projection organization	Serine/threonine-protein kinase N2	Homo sapiens (human)
positive regulation of cytokinesis	Serine/threonine-protein kinase N2	Homo sapiens (human)
apical junction assembly	Serine/threonine-protein kinase N2	Homo sapiens (human)
positive regulation of viral genome replication	Serine/threonine-protein kinase N2	Homo sapiens (human)
positive regulation of mitotic cell cycle	Serine/threonine-protein kinase N2	Homo sapiens (human)
cell division	Serine/threonine-protein kinase N2	Homo sapiens (human)
regulation of cell motility	Serine/threonine-protein kinase N2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase N2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase N2	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to lipopolysaccharide	Mitogen-activated protein kinase 14	Homo sapiens (human)
DNA damage checkpoint signaling	Mitogen-activated protein kinase 14	Homo sapiens (human)
cell morphogenesis	Mitogen-activated protein kinase 14	Homo sapiens (human)
cartilage condensation	Mitogen-activated protein kinase 14	Homo sapiens (human)
angiogenesis	Mitogen-activated protein kinase 14	Homo sapiens (human)
osteoblast differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
placenta development	Mitogen-activated protein kinase 14	Homo sapiens (human)
response to dietary excess	Mitogen-activated protein kinase 14	Homo sapiens (human)
chondrocyte differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Mitogen-activated protein kinase 14	Homo sapiens (human)
glucose metabolic process	Mitogen-activated protein kinase 14	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 14	Homo sapiens (human)
transcription by RNA polymerase II	Mitogen-activated protein kinase 14	Homo sapiens (human)
apoptotic process	Mitogen-activated protein kinase 14	Homo sapiens (human)
chemotaxis	Mitogen-activated protein kinase 14	Homo sapiens (human)
signal transduction	Mitogen-activated protein kinase 14	Homo sapiens (human)
cell surface receptor signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
cell surface receptor protein serine/threonine kinase signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
skeletal muscle tissue development	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of gene expression	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of myotube differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase 14	Homo sapiens (human)
fatty acid oxidation	Mitogen-activated protein kinase 14	Homo sapiens (human)
platelet activation	Mitogen-activated protein kinase 14	Homo sapiens (human)
regulation of ossification	Mitogen-activated protein kinase 14	Homo sapiens (human)
osteoclast differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of cyclase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
response to muramyl dipeptide	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of interleukin-12 production	Mitogen-activated protein kinase 14	Homo sapiens (human)
response to insulin	Mitogen-activated protein kinase 14	Homo sapiens (human)
negative regulation of hippo signaling	Mitogen-activated protein kinase 14	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Mitogen-activated protein kinase 14	Homo sapiens (human)
response to muscle stretch	Mitogen-activated protein kinase 14	Homo sapiens (human)
p38MAPK cascade	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of protein import into nucleus	Mitogen-activated protein kinase 14	Homo sapiens (human)
signal transduction in response to DNA damage	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of erythrocyte differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of myoblast differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Mitogen-activated protein kinase 14	Homo sapiens (human)
glucose import	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of glucose import	Mitogen-activated protein kinase 14	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
stem cell differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
striated muscle cell differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of muscle cell differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Mitogen-activated protein kinase 14	Homo sapiens (human)
bone development	Mitogen-activated protein kinase 14	Homo sapiens (human)
3'-UTR-mediated mRNA stabilization	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to lipoteichoic acid	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to tumor necrosis factor	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to ionizing radiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to UV-B	Mitogen-activated protein kinase 14	Homo sapiens (human)
negative regulation of canonical Wnt signaling pathway	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of brown fat cell differentiation	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase 14	Homo sapiens (human)
stress-induced premature senescence	Mitogen-activated protein kinase 14	Homo sapiens (human)
cellular response to virus	Mitogen-activated protein kinase 14	Homo sapiens (human)
regulation of synaptic membrane adhesion	Mitogen-activated protein kinase 14	Homo sapiens (human)
regulation of cytokine production involved in inflammatory response	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of myoblast fusion	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Mitogen-activated protein kinase 14	Homo sapiens (human)
positive regulation of myeloid dendritic cell cytokine production	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
adaptive immune response	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
protein phosphorylation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
inflammatory response	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
signal transduction	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
long-term memory	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
regulation of T cell differentiation in thymus	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
myeloid dendritic cell differentiation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
regulation of osteoclast differentiation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
positive regulation of DNA-templated transcription	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
protein autophosphorylation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
peptidyl-serine phosphorylation	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
intracellular signal transduction	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
microtubule-based process	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
positive regulation of neuron apoptotic process	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
cell cycle G1/S phase transition	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
positive regulation of JNK cascade	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
ossification	Discoidin domain-containing receptor 2	Homo sapiens (human)
endochondral bone growth	Discoidin domain-containing receptor 2	Homo sapiens (human)
cell adhesion	Discoidin domain-containing receptor 2	Homo sapiens (human)
signal transduction	Discoidin domain-containing receptor 2	Homo sapiens (human)
regulation of extracellular matrix disassembly	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of fibroblast migration	Discoidin domain-containing receptor 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Discoidin domain-containing receptor 2	Homo sapiens (human)
collagen fibril organization	Discoidin domain-containing receptor 2	Homo sapiens (human)
regulation of bone mineralization	Discoidin domain-containing receptor 2	Homo sapiens (human)
biomineral tissue development	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of collagen biosynthetic process	Discoidin domain-containing receptor 2	Homo sapiens (human)
regulation of tissue remodeling	Discoidin domain-containing receptor 2	Homo sapiens (human)
chondrocyte proliferation	Discoidin domain-containing receptor 2	Homo sapiens (human)
response to muscle stretch	Discoidin domain-containing receptor 2	Homo sapiens (human)
collagen-activated tyrosine kinase receptor signaling pathway	Discoidin domain-containing receptor 2	Homo sapiens (human)
negative regulation of apoptotic process	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of osteoblast differentiation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of protein kinase activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein autophosphorylation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of fibroblast proliferation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
cellular response to hypoxia	Discoidin domain-containing receptor 2	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of extracellular matrix disassembly	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of wound healing	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of G1/S transition of mitotic cell cycle	Discoidin domain-containing receptor 2	Homo sapiens (human)
negative regulation of hydrogen peroxide-mediated programmed cell death	Discoidin domain-containing receptor 2	Homo sapiens (human)
cellular response to angiotensin	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell migration	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of hepatic stellate cell proliferation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of hepatic stellate cell activation	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of neuron projection development	Discoidin domain-containing receptor 2	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Discoidin domain-containing receptor 2	Homo sapiens (human)
multicellular organism development	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of kinase activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein phosphorylation	AP2-associated protein kinase 1	Homo sapiens (human)
regulation of protein localization	AP2-associated protein kinase 1	Homo sapiens (human)
positive regulation of Notch signaling pathway	AP2-associated protein kinase 1	Homo sapiens (human)
protein stabilization	AP2-associated protein kinase 1	Homo sapiens (human)
membrane organization	AP2-associated protein kinase 1	Homo sapiens (human)
presynaptic endocytosis	AP2-associated protein kinase 1	Homo sapiens (human)
regulation of clathrin-dependent endocytosis	AP2-associated protein kinase 1	Homo sapiens (human)
regulation of vascular permeability involved in acute inflammatory response	Myosin light chain kinase 3	Homo sapiens (human)
protein phosphorylation	Myosin light chain kinase 3	Homo sapiens (human)
sarcomere organization	Myosin light chain kinase 3	Homo sapiens (human)
sarcomerogenesis	Myosin light chain kinase 3	Homo sapiens (human)
cardiac myofibril assembly	Myosin light chain kinase 3	Homo sapiens (human)
positive regulation of sarcomere organization	Myosin light chain kinase 3	Homo sapiens (human)
cellular response to interleukin-1	Myosin light chain kinase 3	Homo sapiens (human)
biological_process	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
cellular response to heat	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
protein stabilization	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
protein folding	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
natural killer cell differentiation	Rab-like protein 3	Homo sapiens (human)
B cell differentiation	Rab-like protein 3	Homo sapiens (human)
T cell differentiation in thymus	Rab-like protein 3	Homo sapiens (human)
regulation of Ras protein signal transduction	Rab-like protein 3	Homo sapiens (human)
protein stabilization	Rab-like protein 3	Homo sapiens (human)
regulation of protein lipidation	Rab-like protein 3	Homo sapiens (human)
intracellular protein transport	Rab-like protein 3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
actomyosin structure organization	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
actomyosin structure organization	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
fatty acid beta-oxidation	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA dehydrogenase	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
autophagy	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
smoothened signaling pathway	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
negative regulation of smoothened signaling pathway	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
positive regulation of smoothened signaling pathway	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
fibroblast activation	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
cellular senescence	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
reticulophagy	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
piecemeal microautophagy of the nucleus	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
response to starvation	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
autophagosome assembly	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
autophagy of mitochondrion	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
regulation of autophagy	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
fatty acid beta-oxidation	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
fatty acid beta-oxidation using acyl-CoA dehydrogenase	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
mRNA processing	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
rRNA catabolic process	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
apoptotic chromosome condensation	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
response to endoplasmic reticulum stress	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
negative regulation of DNA-templated transcription	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
IRE1-mediated unfolded protein response	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
autophagy of mitochondrion	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
neuron migration	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
positive regulation of neuron projection development	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
Wnt signaling pathway	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
establishment of cell polarity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
activation of protein kinase activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
regulation of axonogenesis	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
regulation of cytoskeleton organization	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
mitochondrion localization	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
axon development	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
establishment or maintenance of cell polarity regulating cell shape	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
regulation of microtubule binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
microtubule cytoskeleton organization	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
central nervous system development	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
DNA duplex unwinding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
mitochondrial large ribosomal subunit assembly	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
microtubule cytoskeleton organization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
DNA repair	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
negative regulation of microtubule depolymerization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
phosphorylation	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
central nervous system neuron development	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
regulation of actin cytoskeleton organization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
positive regulation of JNK cascade	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
regulation of cytoskeleton organization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
neuron cellular homeostasis	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
regulation of microtubule cytoskeleton organization	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
execution phase of apoptosis	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
positive regulation of protein acetylation	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein phosphorylation	STE20-related kinase adapter protein alpha	Homo sapiens (human)
G1 to G0 transition	STE20-related kinase adapter protein alpha	Homo sapiens (human)
protein export from nucleus	STE20-related kinase adapter protein alpha	Homo sapiens (human)
activation of protein kinase activity	STE20-related kinase adapter protein alpha	Homo sapiens (human)
skeletal muscle contraction	Myosin-14	Homo sapiens (human)
mitochondrion organization	Myosin-14	Homo sapiens (human)
skeletal muscle tissue development	Myosin-14	Homo sapiens (human)
sensory perception of sound	Myosin-14	Homo sapiens (human)
regulation of cell shape	Myosin-14	Homo sapiens (human)
neuronal action potential	Myosin-14	Homo sapiens (human)
actin filament-based movement	Myosin-14	Homo sapiens (human)
actomyosin structure organization	Myosin-14	Homo sapiens (human)
vocalization behavior	Myosin-14	Homo sapiens (human)
negative regulation of mitochondrial fusion	AarF domain-containing protein kinase 1	Homo sapiens (human)
positive regulation of cristae formation	AarF domain-containing protein kinase 1	Homo sapiens (human)
mitochondrion organization	AarF domain-containing protein kinase 1	Homo sapiens (human)
lipid homeostasis	AarF domain-containing protein kinase 1	Homo sapiens (human)
protein localization	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
regulation of apoptotic process	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
U2-type prespliceosome assembly	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
response to UV	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
response to tumor necrosis factor	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
MAPK cascade	MAP kinase-activated protein kinase 5	Homo sapiens (human)
regulation of translation	MAP kinase-activated protein kinase 5	Homo sapiens (human)
signal transduction	MAP kinase-activated protein kinase 5	Homo sapiens (human)
Ras protein signal transduction	MAP kinase-activated protein kinase 5	Homo sapiens (human)
negative regulation of TOR signaling	MAP kinase-activated protein kinase 5	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein autophosphorylation	MAP kinase-activated protein kinase 5	Homo sapiens (human)
positive regulation of telomerase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
positive regulation of dendritic spine development	MAP kinase-activated protein kinase 5	Homo sapiens (human)
cellular senescence	MAP kinase-activated protein kinase 5	Homo sapiens (human)
stress-induced premature senescence	MAP kinase-activated protein kinase 5	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	MAP kinase-activated protein kinase 5	Homo sapiens (human)
positive regulation of telomere capping	MAP kinase-activated protein kinase 5	Homo sapiens (human)
peptidyl-serine phosphorylation	MAP kinase-activated protein kinase 5	Homo sapiens (human)
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
translational termination	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
translation	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
protein phosphorylation	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
ubiquinone biosynthetic process	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
phosphorylation	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
regulation of autophagy	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
positive regulation of autophagosome assembly	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase 15	Homo sapiens (human)
regulation of COPII vesicle coating	Mitogen-activated protein kinase 15	Homo sapiens (human)
DNA damage response	Mitogen-activated protein kinase 15	Homo sapiens (human)
endoplasmic reticulum organization	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of cell population proliferation	Mitogen-activated protein kinase 15	Homo sapiens (human)
regulation of autophagy	Mitogen-activated protein kinase 15	Homo sapiens (human)
negative regulation of cell migration	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of telomerase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
dopamine uptake	Mitogen-activated protein kinase 15	Homo sapiens (human)
regulation of cilium assembly	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of telomere capping	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein localization to ciliary transition zone	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of metaphase/anaphase transition of meiosis I	Mitogen-activated protein kinase 15	Homo sapiens (human)
positive regulation of spindle assembly	Mitogen-activated protein kinase 15	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase 15	Homo sapiens (human)
mitotic cell cycle	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
regulation of mitotic cell cycle	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
cellular response to potassium ion	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
spindle assembly	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
positive regulation of telomerase activity	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
positive regulation of telomere capping	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
spliceosomal complex assembly	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
positive regulation of myeloid dendritic cell cytokine production	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
double-strand break repair	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
tRNA splicing, via endonucleolytic cleavage and ligation	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
regulation of translational initiation	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
DNA duplex unwinding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
response to exogenous dsRNA	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
innate immune response	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
defense response to virus	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
nucleic acid metabolic process	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
protein localization to cytoplasmic stress granule	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
inositol phosphate metabolic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
phosphatidylinositol phosphate biosynthetic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
negative regulation of cold-induced thermogenesis	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol phosphate biosynthetic process	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
cell population proliferation	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
positive regulation of MAPK cascade	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
cellular response to phorbol 13-acetate 12-myristate	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Aurora kinase B	Homo sapiens (human)
mitotic cell cycle	Aurora kinase B	Homo sapiens (human)
mitotic cytokinesis	Aurora kinase B	Homo sapiens (human)
negative regulation of B cell apoptotic process	Aurora kinase B	Homo sapiens (human)
protein phosphorylation	Aurora kinase B	Homo sapiens (human)
spindle organization	Aurora kinase B	Homo sapiens (human)
attachment of spindle microtubules to kinetochore	Aurora kinase B	Homo sapiens (human)
abscission	Aurora kinase B	Homo sapiens (human)
negative regulation of protein binding	Aurora kinase B	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Aurora kinase B	Homo sapiens (human)
negative regulation of cytokinesis	Aurora kinase B	Homo sapiens (human)
positive regulation of cytokinesis	Aurora kinase B	Homo sapiens (human)
protein localization to kinetochore	Aurora kinase B	Homo sapiens (human)
cellular response to UV	Aurora kinase B	Homo sapiens (human)
cleavage furrow formation	Aurora kinase B	Homo sapiens (human)
post-translational protein modification	Aurora kinase B	Homo sapiens (human)
cell cycle G2/M phase transition	Aurora kinase B	Homo sapiens (human)
mitotic cytokinesis checkpoint signaling	Aurora kinase B	Homo sapiens (human)
negative regulation of innate immune response	Aurora kinase B	Homo sapiens (human)
protein autophosphorylation	Aurora kinase B	Homo sapiens (human)
mitotic spindle midzone assembly	Aurora kinase B	Homo sapiens (human)
positive regulation of telomerase activity	Aurora kinase B	Homo sapiens (human)
regulation of chromosome segregation	Aurora kinase B	Homo sapiens (human)
positive regulation of mitotic sister chromatid segregation	Aurora kinase B	Homo sapiens (human)
positive regulation of mitotic cell cycle spindle assembly checkpoint	Aurora kinase B	Homo sapiens (human)
mitotic spindle assembly	Aurora kinase B	Homo sapiens (human)
negative regulation of cGAS/STING signaling pathway	Aurora kinase B	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	Aurora kinase B	Homo sapiens (human)
positive regulation of mitotic sister chromatid separation	Aurora kinase B	Homo sapiens (human)
positive regulation of attachment of mitotic spindle microtubules to kinetochore	Aurora kinase B	Homo sapiens (human)
positive regulation of mitotic cytokinesis	Aurora kinase B	Homo sapiens (human)
positive regulation of telomere capping	Aurora kinase B	Homo sapiens (human)
positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore	Aurora kinase B	Homo sapiens (human)
mitotic spindle organization	Aurora kinase B	Homo sapiens (human)
regulation of cytokinesis	Aurora kinase B	Homo sapiens (human)
microtubule cytoskeleton organization	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of cell cycle	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule cytoskeleton organization	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule bundle formation	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
protein phosphorylation	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
nervous system development	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of programmed cell death	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cilium organization	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of cilium assembly	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
regulation of centrosome cycle	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cell division	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
positive regulation of protein localization to centrosome	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
intracellular signal transduction	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
cell division	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
cilium assembly	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
MAPK cascade	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
positive regulation of protein phosphorylation	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein phosphorylation	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
calcium-mediated signaling	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
cellular response to reactive oxygen species	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
regulation of protein kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
positive regulation of DNA-templated transcription	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein autophosphorylation	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
CAMKK-AMPK signaling cascade	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
positive regulation of autophagy of mitochondrion	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein phosphorylation	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
tRNA processing	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
regulation of signal transduction by p53 class mediator	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
tRNA threonylcarbamoyladenosine metabolic process	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
regulation of cyclin-dependent protein serine/threonine kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
mitotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
regulation of mitotic nuclear division	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
negative regulation of G2/M transition of mitotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
protein phosphorylation	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
negative regulation of G2/MI transition of meiotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
meiotic cell cycle	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
response to ischemia	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to amino acid starvation	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
response to endoplasmic reticulum stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
neuron intrinsic apoptotic signaling pathway in response to oxidative stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
innate immune response	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of myoblast differentiation	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of protein kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of DNA-templated transcription	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of JNK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
neuron apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to hydrogen peroxide	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to tumor necrosis factor	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
endothelial cell apoptotic process	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular senescence	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
apoptotic signaling pathway	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
programmed necrotic cell death	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to reactive nitrogen species	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cellular response to stress	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
blood vessel development	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
positive regulation of cell proliferation in bone marrow	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
positive regulation of p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
negative regulation of cellular senescence	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
acute inflammatory response	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
phagocytosis	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
negative regulation of cell population proliferation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
regulation of eIF2 alpha phosphorylation by heme	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
macrophage differentiation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
negative regulation of translational initiation by iron	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protoporphyrinogen IX metabolic process	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protein autophosphorylation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
negative regulation of hemoglobin biosynthetic process	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
establishment of localization in cell	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
multicellular organismal-level iron ion homeostasis	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
integrated stress response signaling	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
HRI-mediated signaling	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
positive regulation of mitophagy	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
response to iron ion starvation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
regulation of translational initiation by eIF2 alpha phosphorylation	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
regulation of cyclin-dependent protein serine/threonine kinase activity	Nucleolar GTP-binding protein 1	Homo sapiens (human)
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Nucleolar GTP-binding protein 1	Homo sapiens (human)
osteoblast differentiation	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of DNA replication	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of cell population proliferation	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of cell-cell adhesion	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of cell migration	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of protein ubiquitination	Nucleolar GTP-binding protein 1	Homo sapiens (human)
negative regulation of collagen binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
ribosomal large subunit biogenesis	Nucleolar GTP-binding protein 1	Homo sapiens (human)
protein stabilization	Nucleolar GTP-binding protein 1	Homo sapiens (human)
angiogenesis	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Serine/threonine-protein kinase D2	Homo sapiens (human)
adaptive immune response	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase D2	Homo sapiens (human)
cell adhesion	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of endothelial cell migration	Serine/threonine-protein kinase D2	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase D2	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase D2	Homo sapiens (human)
sphingolipid biosynthetic process	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of vascular endothelial growth factor receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of interleukin-2 production	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of interleukin-8 production	Serine/threonine-protein kinase D2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase D2	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of fibroblast growth factor receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of angiogenesis	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of cell adhesion	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase D2	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
T cell receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of T cell receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of DNA-binding transcription factor activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
endothelial tube morphogenesis	Serine/threonine-protein kinase D2	Homo sapiens (human)
regulation of T cell apoptotic process	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of DNA biosynthetic process	Serine/threonine-protein kinase D2	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Serine/threonine-protein kinase D2	Homo sapiens (human)
phospholipase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein phosphorylation	NUAK family SNF1-like kinase 2	Homo sapiens (human)
apoptotic process	NUAK family SNF1-like kinase 2	Homo sapiens (human)
actin cytoskeleton organization	NUAK family SNF1-like kinase 2	Homo sapiens (human)
protein localization to nucleus	NUAK family SNF1-like kinase 2	Homo sapiens (human)
regulation of hippo signaling	NUAK family SNF1-like kinase 2	Homo sapiens (human)
cellular response to glucose starvation	NUAK family SNF1-like kinase 2	Homo sapiens (human)
negative regulation of apoptotic process	NUAK family SNF1-like kinase 2	Homo sapiens (human)
rRNA modification	RNA cytidine acetyltransferase	Homo sapiens (human)
regulation of translation	RNA cytidine acetyltransferase	Homo sapiens (human)
protein acetylation	RNA cytidine acetyltransferase	Homo sapiens (human)
regulation of centrosome duplication	RNA cytidine acetyltransferase	Homo sapiens (human)
negative regulation of telomere maintenance via telomerase	RNA cytidine acetyltransferase	Homo sapiens (human)
ribosomal small subunit biogenesis	RNA cytidine acetyltransferase	Homo sapiens (human)
positive regulation of translation	RNA cytidine acetyltransferase	Homo sapiens (human)
tRNA acetylation	RNA cytidine acetyltransferase	Homo sapiens (human)
rRNA acetylation involved in maturation of SSU-rRNA	RNA cytidine acetyltransferase	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
regulation of insulin receptor signaling pathway	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
apoptotic process	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
regulation of cell migration	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cytoplasmic microtubule organization	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
regulation of apoptotic process	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein autophosphorylation	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
regulation of focal adhesion assembly	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein phosphorylation	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
DNA repair	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
positive regulation of JUN kinase activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
negative regulation of JNK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
positive regulation of JNK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
neuron projection morphogenesis	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
dTTP catabolic process	dCTP pyrophosphatase 1	Homo sapiens (human)
dCTP catabolic process	dCTP pyrophosphatase 1	Homo sapiens (human)
nucleoside triphosphate catabolic process	dCTP pyrophosphatase 1	Homo sapiens (human)
DNA protection	dCTP pyrophosphatase 1	Homo sapiens (human)
regulation of RNA splicing	Dual specificity protein kinase CLK4	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Dual specificity protein kinase CLK4	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform gamma-1	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform gamma-1	Homo sapiens (human)
signal transduction	Casein kinase I isoform gamma-1	Homo sapiens (human)
endocytosis	Casein kinase I isoform gamma-1	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform gamma-1	Homo sapiens (human)
regulation of DNA-templated transcription	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cytoskeleton organization	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
learning	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
memory	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
locomotory behavior	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
neuron projection arborization	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
neuron projection extension	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
regulation of MAPK cascade	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
translation	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
phenylalanyl-tRNA aminoacylation	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
protein heterotetramerization	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
tRNA aminoacylation for protein translation	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
aminoacyl-tRNA metabolism involved in translational fidelity	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
isoleucyl-tRNA aminoacylation	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
mitochondrial translation	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
positive regulation of Notch signaling pathway	BMP-2-inducible protein kinase	Homo sapiens (human)
regulation of clathrin-dependent endocytosis	BMP-2-inducible protein kinase	Homo sapiens (human)
regulation of bone mineralization	BMP-2-inducible protein kinase	Homo sapiens (human)
ATP metabolic process	Obg-like ATPase 1	Homo sapiens (human)
ribosomal large subunit assembly	Midasin	Homo sapiens (human)
ribosomal large subunit export from nucleus	Midasin	Homo sapiens (human)
apoptotic process	SAFB-like transcription modulator	Homo sapiens (human)
regulation of mRNA processing	SAFB-like transcription modulator	Homo sapiens (human)
regulation of transcription by RNA polymerase II	SAFB-like transcription modulator	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
neutrophil mediated immunity	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
JNK cascade	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
toll-like receptor 9 signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
interleukin-33-mediated signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
innate immune response	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
neutrophil migration	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
cytokine-mediated signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
Toll signaling pathway	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
cellular response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
intracellular signal transduction	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
positive regulation of programmed cell death	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
GCN2-mediated signaling	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
pyroptosis	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
DNA damage checkpoint signaling	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
inflammatory response	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cytoskeleton organization	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
JNK cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cell death	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cell differentiation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
stress-activated protein kinase signaling cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
embryonic digit morphogenesis	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
positive regulation of apoptotic process	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein autophosphorylation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
stress-activated MAPK cascade	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
limb development	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cellular response to gamma radiation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cellular response to UV-B	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
positive regulation of mitotic DNA damage checkpoint	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
peptidyl-serine phosphorylation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
regulation of mitotic metaphase/anaphase transition	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
chromosome segregation	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
transcription by RNA polymerase II	Cyclin-dependent kinase 12	Homo sapiens (human)
mRNA processing	Cyclin-dependent kinase 12	Homo sapiens (human)
RNA splicing	Cyclin-dependent kinase 12	Homo sapiens (human)
positive regulation of transcription elongation by RNA polymerase II	Cyclin-dependent kinase 12	Homo sapiens (human)
regulation of MAP kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 12	Homo sapiens (human)
protein autophosphorylation	Cyclin-dependent kinase 12	Homo sapiens (human)
regulation of cell cycle	Cyclin-dependent kinase 12	Homo sapiens (human)
negative regulation of stem cell differentiation	Cyclin-dependent kinase 12	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 12	Homo sapiens (human)
aerobic respiration	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
negative regulation of cell growth	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial respiratory chain complex I assembly	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
cellular response to interferon-beta	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
proton motive force-driven mitochondrial ATP synthesis	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
protein insertion into mitochondrial inner membrane	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
positive regulation of protein catabolic process	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
negative regulation of DNA-templated transcription	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
cellular response to retinoic acid	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
reactive oxygen species metabolic process	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
apoptotic signaling pathway	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
extrinsic apoptotic signaling pathway	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
positive regulation of execution phase of apoptosis	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 26	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase 26	Homo sapiens (human)
cellular response to starvation	Serine/threonine-protein kinase 26	Homo sapiens (human)
microvillus assembly	Serine/threonine-protein kinase 26	Homo sapiens (human)
negative regulation of cell migration	Serine/threonine-protein kinase 26	Homo sapiens (human)
cellular response to oxidative stress	Serine/threonine-protein kinase 26	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase 26	Homo sapiens (human)
regulation of apoptotic process	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 26	Homo sapiens (human)
tricarboxylic acid cycle	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinate metabolic process	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinyl-CoA pathway	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinyl-CoA catabolic process	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinyl-CoA metabolic process	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
MAPK cascade	Serine/threonine-protein kinase NLK	Homo sapiens (human)
regulation of DNA-templated transcription	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase NLK	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Serine/threonine-protein kinase NLK	Homo sapiens (human)
Wnt signaling pathway, calcium modulating pathway	Serine/threonine-protein kinase NLK	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase NLK	Homo sapiens (human)
negative regulation of Wnt signaling pathway	Serine/threonine-protein kinase NLK	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein stabilization	Serine/threonine-protein kinase NLK	Homo sapiens (human)
cellular response to osmotic stress	Serine/threonine-protein kinase NLK	Homo sapiens (human)
negative regulation of TORC1 signaling	Serine/threonine-protein kinase NLK	Homo sapiens (human)
positive regulation of receptor signaling pathway via STAT	Serine/threonine-protein kinase NLK	Homo sapiens (human)
glycogen metabolic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of glycolytic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
negative regulation of protein kinase activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
fatty acid biosynthetic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
ATP biosynthetic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylation	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
sterol biosynthetic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of fatty acid metabolic process	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cellular response to nutrient levels	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
intracellular signal transduction	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
positive regulation of protein kinase activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of fatty acid oxidation	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of glucose import	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
regulation of catalytic activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein phosphorylation	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
activation of innate immune response	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cytoplasmic pattern recognition receptor signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
inflammatory response	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
canonical NF-kappaB signal transduction	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
response to virus	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
negative regulation of gene expression	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of macroautophagy	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
regulation of type I interferon production	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of type I interferon production	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of interferon-alpha production	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of interferon-beta production	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
dendritic cell proliferation	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
innate immune response	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
defense response to Gram-positive bacterium	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
defense response to virus	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
type I interferon-mediated signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of type I interferon-mediated signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
antiviral innate immune response	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cGAS/STING signaling pathway	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
negative regulation of TORC1 signaling	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of TORC1 signaling	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of xenophagy	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
macroautophagy	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
positive regulation of non-motile cilium assembly	Septin-9	Homo sapiens (human)
protein localization	Septin-9	Homo sapiens (human)
cytoskeleton-dependent cytokinesis	Septin-9	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
signal transduction	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
central nervous system development	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
negative regulation of embryonic development	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
negative regulation of mesoderm development	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
peptidyl-serine phosphorylation	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
positive regulation of protein phosphorylation	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein phosphorylation	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytoskeleton organization	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
response to organonitrogen compound	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
Wnt signaling pathway	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
microvillus assembly	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
actin cytoskeleton organization	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
intracellular signal transduction	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
positive regulation of JNK cascade	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein autophosphorylation	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
regulation of dendrite morphogenesis	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein localization to plasma membrane	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
neuron projection morphogenesis	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
regulation of MAPK cascade	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
MAPK cascade	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
regulation of cell growth	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein targeting to membrane	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
DNA damage response	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
axonogenesis	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
regulation of cell shape	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
positive regulation of protein autophosphorylation	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
activation of protein kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
positive regulation of stress-activated MAPK cascade	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
regulation of actin cytoskeleton organization	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
positive regulation of MAPK cascade	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
positive regulation of JNK cascade	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
focal adhesion assembly	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
stress-activated MAPK cascade	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
basal dendrite morphogenesis	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
basal dendrite arborization	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
long-chain fatty acid metabolic process	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
long-chain fatty-acyl-CoA biosynthetic process	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
positive regulation of long-chain fatty acid import across plasma membrane	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
protein autophosphorylation	ALK tyrosine kinase receptor	Homo sapiens (human)
signal transduction	ALK tyrosine kinase receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	ALK tyrosine kinase receptor	Homo sapiens (human)
phosphorylation	ALK tyrosine kinase receptor	Homo sapiens (human)
hippocampus development	ALK tyrosine kinase receptor	Homo sapiens (human)
adult behavior	ALK tyrosine kinase receptor	Homo sapiens (human)
swimming behavior	ALK tyrosine kinase receptor	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	ALK tyrosine kinase receptor	Homo sapiens (human)
regulation of apoptotic process	ALK tyrosine kinase receptor	Homo sapiens (human)
protein autophosphorylation	ALK tyrosine kinase receptor	Homo sapiens (human)
neuron development	ALK tyrosine kinase receptor	Homo sapiens (human)
negative regulation of lipid catabolic process	ALK tyrosine kinase receptor	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	ALK tyrosine kinase receptor	Homo sapiens (human)
regulation of dopamine receptor signaling pathway	ALK tyrosine kinase receptor	Homo sapiens (human)
response to environmental enrichment	ALK tyrosine kinase receptor	Homo sapiens (human)
energy homeostasis	ALK tyrosine kinase receptor	Homo sapiens (human)
positive regulation of dendrite development	ALK tyrosine kinase receptor	Homo sapiens (human)
regulation of neuron differentiation	ALK tyrosine kinase receptor	Homo sapiens (human)
regulation of cell population proliferation	ALK tyrosine kinase receptor	Homo sapiens (human)
multicellular organism development	ALK tyrosine kinase receptor	Homo sapiens (human)
positive regulation of kinase activity	ALK tyrosine kinase receptor	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase ICK	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase ICK	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase ICK	Homo sapiens (human)
intraciliary anterograde transport	Serine/threonine-protein kinase ICK	Homo sapiens (human)
intraciliary retrograde transport	Serine/threonine-protein kinase ICK	Homo sapiens (human)
intraciliary transport	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cilium assembly	Serine/threonine-protein kinase ICK	Homo sapiens (human)
mitochondrial genome maintenance	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of endothelial cell proliferation	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
protein phosphorylation	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
signal transduction	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of TOR signaling	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of angiogenesis	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell size	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
brain morphogenesis	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
homeostasis of number of cells within a tissue	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of vascular endothelial cell proliferation	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
positive regulation of artery morphogenesis	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
negative regulation of cellular senescence	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
intracellular signal transduction	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
peptidyl-serine phosphorylation	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
positive regulation of TORC1 signaling	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
positive regulation of TORC2 signaling	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
microtubule cytoskeleton organization	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
cellular response to mechanical stimulus	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
regulation of alternative mRNA splicing, via spliceosome	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear-transcribed mRNA catabolic process	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
mRNA processing	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
circadian rhythm	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
RNA splicing	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
positive regulation of circadian rhythm	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
positive regulation of DNA-templated transcription	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
positive regulation of mRNA splicing, via spliceosome	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
mRNA stabilization	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
DNA repair	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
myoblast fusion	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
positive regulation of DNA-templated transcription	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
adipose tissue development	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
peptidyl-serine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
peptidyl-threonine phosphorylation	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
protein phosphorylation	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
regulation of T cell mediated cytotoxicity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of adaptive immune response	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of phosphatase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
activation of protein kinase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of type II interferon production	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
T cell differentiation in thymus	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein modification process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
non-canonical NF-kappaB signal transduction	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of apoptotic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
T cell homeostasis	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of DNA-templated transcription	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of activated T cell proliferation	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein autophosphorylation	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
lymph node development	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
spleen development	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
thymus development	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
defense response to virus	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of necroptotic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of activation-induced cell death of T cells	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
necroptotic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
cellular response to hydrogen peroxide	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
reactive oxygen species metabolic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
apoptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
programmed necrotic cell death	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
necroptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
execution phase of necroptosis	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
amyloid fibril formation	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathway	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
signal transduction	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cytoskeleton organization	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
establishment or maintenance of cell polarity	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cell migration	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
actin cytoskeleton organization	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
actomyosin structure organization	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
positive regulation of cytokine production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of cytokine-mediated signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
MyD88-dependent toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein phosphorylation	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to virus	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
positive regulation of macrophage tolerance induction	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of macrophage cytokine production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
cytokine-mediated signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of NF-kappaB transcription factor activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to peptidoglycan	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of interleukin-12 production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of interleukin-6 production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of tumor necrosis factor production	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of toll-like receptor signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of protein catabolic process	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of protein-containing complex disassembly	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
regulation of protein-containing complex disassembly	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to exogenous dsRNA	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of MAP kinase activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
negative regulation of innate immune response	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
interleukin-1-mediated signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
response to interleukin-1	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
Toll signaling pathway	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
cellular response to lipopolysaccharide	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
intracellular signal transduction	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein phosphorylation	Serine/threonine-protein kinase 24	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase 24	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Serine/threonine-protein kinase 24	Homo sapiens (human)
cellular response to starvation	Serine/threonine-protein kinase 24	Homo sapiens (human)
negative regulation of cell migration	Serine/threonine-protein kinase 24	Homo sapiens (human)
cellular response to oxidative stress	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase 24	Homo sapiens (human)
regulation of axon regeneration	Serine/threonine-protein kinase 24	Homo sapiens (human)
positive regulation of axon regeneration	Serine/threonine-protein kinase 24	Homo sapiens (human)
execution phase of apoptosis	Serine/threonine-protein kinase 24	Homo sapiens (human)
Wnt signaling pathway	Casein kinase I isoform gamma-3	Homo sapiens (human)
protein modification process	Casein kinase I isoform gamma-3	Homo sapiens (human)
peptidyl-serine phosphorylation	Casein kinase I isoform gamma-3	Homo sapiens (human)
signal transduction	Casein kinase I isoform gamma-3	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Casein kinase I isoform gamma-3	Homo sapiens (human)
endocytosis	Casein kinase I isoform gamma-3	Homo sapiens (human)
MAPK cascade	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
placenta development	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
response to UV-C	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
regulation of gene expression	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
male germ-line sex determination	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
intracellular signal transduction	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of JUN kinase activity	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of telomerase activity	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
chorionic trophoblast cell differentiation	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of p38MAPK cascade	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
positive regulation of telomere capping	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (505)

Process	via Protein(s)	Taxonomy
protein serine/threonine kinase activity	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
transmembrane signaling receptor activity	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
protein binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
ATP binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
BMP binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
SMAD binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
metal ion binding	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
BMP receptor activity	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
transforming growth factor beta receptor activity, type I	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
amyloid-beta binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
steroid binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
protein binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
heme binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
protein homodimerization activity	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
metal ion binding	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
protein kinase activity	Cell division cycle 7-related protein kinase	Homo sapiens (human)
protein binding	Cell division cycle 7-related protein kinase	Homo sapiens (human)
ATP binding	Cell division cycle 7-related protein kinase	Homo sapiens (human)
kinase activity	Cell division cycle 7-related protein kinase	Homo sapiens (human)
metal ion binding	Cell division cycle 7-related protein kinase	Homo sapiens (human)
protein serine kinase activity	Cell division cycle 7-related protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Cell division cycle 7-related protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
DNA binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
DNA helicase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA helicase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
mRNA binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
GTPase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
protein binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ATP binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
transcription factor binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
poly(A) binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
eukaryotic initiation factor 4E binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ATP hydrolysis activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ribonucleoside triphosphate phosphatase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
translation initiation factor binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA strand annealing activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
signaling adaptor activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
RNA stem-loop binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
gamma-tubulin binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ribosomal small subunit binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
CTPase activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
protein serine/threonine kinase activator activity	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cadherin binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
mRNA 5'-UTR binding	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
magnesium ion binding	Pyridoxal kinase	Homo sapiens (human)
ATP binding	Pyridoxal kinase	Homo sapiens (human)
zinc ion binding	Pyridoxal kinase	Homo sapiens (human)
pyridoxal kinase activity	Pyridoxal kinase	Homo sapiens (human)
pyridoxal phosphate binding	Pyridoxal kinase	Homo sapiens (human)
potassium ion binding	Pyridoxal kinase	Homo sapiens (human)
sodium ion binding	Pyridoxal kinase	Homo sapiens (human)
lithium ion binding	Pyridoxal kinase	Homo sapiens (human)
protein homodimerization activity	Pyridoxal kinase	Homo sapiens (human)
transcription coactivator binding	Citron Rho-interacting kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Citron Rho-interacting kinase	Homo sapiens (human)
protein binding	Citron Rho-interacting kinase	Homo sapiens (human)
ATP binding	Citron Rho-interacting kinase	Homo sapiens (human)
SH3 domain binding	Citron Rho-interacting kinase	Homo sapiens (human)
protein kinase binding	Citron Rho-interacting kinase	Homo sapiens (human)
PDZ domain binding	Citron Rho-interacting kinase	Homo sapiens (human)
protein serine/threonine kinase inhibitor activity	Citron Rho-interacting kinase	Homo sapiens (human)
metal ion binding	Citron Rho-interacting kinase	Homo sapiens (human)
scaffold protein binding	Citron Rho-interacting kinase	Homo sapiens (human)
protein serine kinase activity	Citron Rho-interacting kinase	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein domain specific binding	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
histone H3T11 kinase activity	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein kinase activity	Aurora kinase A	Homo sapiens (human)
protein serine/threonine kinase activity	Aurora kinase A	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Aurora kinase A	Homo sapiens (human)
protein binding	Aurora kinase A	Homo sapiens (human)
ATP binding	Aurora kinase A	Homo sapiens (human)
protein kinase binding	Aurora kinase A	Homo sapiens (human)
ubiquitin protein ligase binding	Aurora kinase A	Homo sapiens (human)
histone H3S10 kinase activity	Aurora kinase A	Homo sapiens (human)
protein heterodimerization activity	Aurora kinase A	Homo sapiens (human)
protein serine kinase activity	Aurora kinase A	Homo sapiens (human)
molecular function activator activity	Aurora kinase A	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-G-associated kinase	Homo sapiens (human)
protein binding	Cyclin-G-associated kinase	Homo sapiens (human)
ATP binding	Cyclin-G-associated kinase	Homo sapiens (human)
cyclin binding	Cyclin-G-associated kinase	Homo sapiens (human)
protein-folding chaperone binding	Cyclin-G-associated kinase	Homo sapiens (human)
protein serine kinase activity	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin binding	Cyclin-G-associated kinase	Homo sapiens (human)
ephrin receptor activity	Ephrin type-B receptor 6	Homo sapiens (human)
protein binding	Ephrin type-B receptor 6	Homo sapiens (human)
ATP binding	Ephrin type-B receptor 6	Homo sapiens (human)
signaling receptor activity	Ephrin type-B receptor 6	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-B receptor 6	Homo sapiens (human)
FAD binding	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
flavin adenine dinucleotide binding	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
pristanoyl-CoA oxidase activity	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
fatty acid binding	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
signaling receptor binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
ATP binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
LIM domain binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
signaling adaptor activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
identical protein binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein homodimerization activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
CARD domain binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
caspase binding	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein serine kinase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
JUN kinase kinase kinase activity	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein kinase activity	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
protein serine/threonine kinase activity	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
protein binding	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
ATP binding	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
protein serine kinase activity	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
histone H2A kinase activity	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
magnesium ion binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
GTPase activity	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
protein binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
GTP binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
phosphatidic acid binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
GTPase-dependent fusogenic activity	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
membrane bending activity	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cardiolipin binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
microtubule binding	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
protein kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
growth hormone receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-12 receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
protein kinase binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
heme binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
type 1 angiotensin receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
acetylcholine receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
histone H3Y41 kinase activity	Tyrosine-protein kinase JAK2	Homo sapiens (human)
SH2 domain binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
histone binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
insulin receptor substrate binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
peptide hormone receptor binding	Tyrosine-protein kinase JAK2	Homo sapiens (human)
tRNA binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
RNA binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
translation initiation factor activity	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
GTPase activity	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
protein binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
GTP binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
metal ion binding	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
protease binding	Rho-associated protein kinase 2	Homo sapiens (human)
RNA binding	Rho-associated protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Rho-associated protein kinase 2	Homo sapiens (human)
structural molecule activity	Rho-associated protein kinase 2	Homo sapiens (human)
protein binding	Rho-associated protein kinase 2	Homo sapiens (human)
ATP binding	Rho-associated protein kinase 2	Homo sapiens (human)
small GTPase binding	Rho-associated protein kinase 2	Homo sapiens (human)
metal ion binding	Rho-associated protein kinase 2	Homo sapiens (human)
tau protein binding	Rho-associated protein kinase 2	Homo sapiens (human)
tau-protein kinase activity	Rho-associated protein kinase 2	Homo sapiens (human)
endopeptidase activator activity	Rho-associated protein kinase 2	Homo sapiens (human)
Rho-dependent protein serine/threonine kinase activity	Rho-associated protein kinase 2	Homo sapiens (human)
protein serine kinase activity	Rho-associated protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein-containing complex binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
GTPase binding	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
RNA endonuclease activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
platelet-derived growth factor receptor binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
enzyme binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
Hsp70 protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
ADP binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
Hsp90 protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
unfolded protein binding	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein tyrosine kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
histone H3S10 kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
histone H3S28 kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
histone H2AS1 kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
RNA binding	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
RNA helicase activity	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
helicase activity	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
protein binding	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
ATP binding	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
ATP hydrolysis activity	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
identical protein binding	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
histone H3S10 kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
histone H3S28 kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Serine/threonine-protein kinase 16	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 16	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 16	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 10	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 10	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase 10	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 10	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase D3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase D3	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
single-stranded DNA binding	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
protein binding	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
ATP binding	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
ATP hydrolysis activity	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
chromatin binding	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
magnesium ion binding	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)
creatine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
microtubule binding	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
nuclear estrogen receptor binding	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cadherin binding involved in cell-cell adhesion	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
supercoiled DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
magnesium ion binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
four-way junction DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
bubble DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
transcription coactivator activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin monomer binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nicotinate-nucleotide adenylyltransferase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein kinase C binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
kinase activity	Tyrosine-protein kinase ABL1	Homo sapiens (human)
SH3 domain binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
syntaxin binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
manganese ion binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuropilin binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
SH2 domain binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
ephrin receptor binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin filament binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mitogen-activated protein kinase binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
proline-rich region binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
delta-catenin binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
sequence-specific double-stranded DNA binding	Tyrosine-protein kinase ABL1	Homo sapiens (human)
epidermal growth factor receptor activity	Epidermal growth factor receptor	Homo sapiens (human)
virus receptor activity	Epidermal growth factor receptor	Homo sapiens (human)
chromatin binding	Epidermal growth factor receptor	Homo sapiens (human)
double-stranded DNA binding	Epidermal growth factor receptor	Homo sapiens (human)
MAP kinase kinase kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
protein tyrosine kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Epidermal growth factor receptor	Homo sapiens (human)
transmembrane signaling receptor activity	Epidermal growth factor receptor	Homo sapiens (human)
epidermal growth factor receptor activity	Epidermal growth factor receptor	Homo sapiens (human)
integrin binding	Epidermal growth factor receptor	Homo sapiens (human)
protein binding	Epidermal growth factor receptor	Homo sapiens (human)
calmodulin binding	Epidermal growth factor receptor	Homo sapiens (human)
ATP binding	Epidermal growth factor receptor	Homo sapiens (human)
enzyme binding	Epidermal growth factor receptor	Homo sapiens (human)
kinase binding	Epidermal growth factor receptor	Homo sapiens (human)
protein kinase binding	Epidermal growth factor receptor	Homo sapiens (human)
protein phosphatase binding	Epidermal growth factor receptor	Homo sapiens (human)
protein tyrosine kinase activator activity	Epidermal growth factor receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activator activity	Epidermal growth factor receptor	Homo sapiens (human)
ubiquitin protein ligase binding	Epidermal growth factor receptor	Homo sapiens (human)
identical protein binding	Epidermal growth factor receptor	Homo sapiens (human)
cadherin binding	Epidermal growth factor receptor	Homo sapiens (human)
actin filament binding	Epidermal growth factor receptor	Homo sapiens (human)
ATPase binding	Epidermal growth factor receptor	Homo sapiens (human)
epidermal growth factor binding	Epidermal growth factor receptor	Homo sapiens (human)
cytokine activity	Interferon beta	Homo sapiens (human)
cytokine receptor binding	Interferon beta	Homo sapiens (human)
type I interferon receptor binding	Interferon beta	Homo sapiens (human)
protein binding	Interferon beta	Homo sapiens (human)
chloramphenicol O-acetyltransferase activity	Interferon beta	Homo sapiens (human)
TAP binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
signaling receptor binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protein binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
peptide antigen binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
TAP binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protein-folding chaperone binding	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
protein tyrosine kinase activity	High affinity nerve growth factor receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	High affinity nerve growth factor receptor	Homo sapiens (human)
GPI-linked ephrin receptor activity	High affinity nerve growth factor receptor	Homo sapiens (human)
neurotrophin p75 receptor binding	High affinity nerve growth factor receptor	Homo sapiens (human)
protein binding	High affinity nerve growth factor receptor	Homo sapiens (human)
ATP binding	High affinity nerve growth factor receptor	Homo sapiens (human)
nerve growth factor receptor activity	High affinity nerve growth factor receptor	Homo sapiens (human)
kinase binding	High affinity nerve growth factor receptor	Homo sapiens (human)
identical protein binding	High affinity nerve growth factor receptor	Homo sapiens (human)
protein homodimerization activity	High affinity nerve growth factor receptor	Homo sapiens (human)
nerve growth factor binding	High affinity nerve growth factor receptor	Homo sapiens (human)
neurotrophin binding	High affinity nerve growth factor receptor	Homo sapiens (human)
neurotrophin receptor activity	High affinity nerve growth factor receptor	Homo sapiens (human)
protein binding	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
GTP binding	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
metal ion binding	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
G-protein beta/gamma-subunit complex binding	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
G protein-coupled receptor binding	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
GTPase activity	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
adenine nucleotide transmembrane transporter activity	ADP/ATP translocase 2	Homo sapiens (human)
RNA binding	ADP/ATP translocase 2	Homo sapiens (human)
ATP:ADP antiporter activity	ADP/ATP translocase 2	Homo sapiens (human)
protein binding	ADP/ATP translocase 2	Homo sapiens (human)
proton transmembrane transporter activity	ADP/ATP translocase 2	Homo sapiens (human)
adenine transmembrane transporter activity	ADP/ATP translocase 2	Homo sapiens (human)
oxidative phosphorylation uncoupler activity	ADP/ATP translocase 2	Homo sapiens (human)
ubiquitin protein ligase binding	ADP/ATP translocase 2	Homo sapiens (human)
chromatin binding	Protein kinase C beta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C beta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C beta type	Homo sapiens (human)
protein kinase C binding	Protein kinase C beta type	Homo sapiens (human)
calcium channel regulator activity	Protein kinase C beta type	Homo sapiens (human)
protein binding	Protein kinase C beta type	Homo sapiens (human)
ATP binding	Protein kinase C beta type	Homo sapiens (human)
zinc ion binding	Protein kinase C beta type	Homo sapiens (human)
nuclear receptor coactivator activity	Protein kinase C beta type	Homo sapiens (human)
histone H3T6 kinase activity	Protein kinase C beta type	Homo sapiens (human)
histone binding	Protein kinase C beta type	Homo sapiens (human)
nuclear androgen receptor binding	Protein kinase C beta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C beta type	Homo sapiens (human)
amyloid-beta binding	Insulin receptor	Homo sapiens (human)
protein tyrosine kinase activity	Insulin receptor	Homo sapiens (human)
insulin receptor activity	Insulin receptor	Homo sapiens (human)
insulin-like growth factor receptor binding	Insulin receptor	Homo sapiens (human)
protein binding	Insulin receptor	Homo sapiens (human)
ATP binding	Insulin receptor	Homo sapiens (human)
GTP binding	Insulin receptor	Homo sapiens (human)
protein domain specific binding	Insulin receptor	Homo sapiens (human)
insulin-like growth factor I binding	Insulin receptor	Homo sapiens (human)
insulin-like growth factor II binding	Insulin receptor	Homo sapiens (human)
cargo receptor activity	Insulin receptor	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Insulin receptor	Homo sapiens (human)
insulin binding	Insulin receptor	Homo sapiens (human)
insulin receptor substrate binding	Insulin receptor	Homo sapiens (human)
protein-containing complex binding	Insulin receptor	Homo sapiens (human)
PTB domain binding	Insulin receptor	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein serine/threonine phosphatase activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
phospholipase activator activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein kinase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein phosphatase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
SH2 domain binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
CD4 receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
CD8 receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
ATPase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
phospholipase activator activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
enzyme binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
type 5 metabotropic glutamate receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
alpha-tubulin binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
transmembrane transporter binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
ephrin receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
tau protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
tau-protein kinase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
growth factor receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
scaffold protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
disordered domain specific binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
virus receptor activity	Cyclin-dependent kinase 1	Homo sapiens (human)
chromatin binding	Cyclin-dependent kinase 1	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 1	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 1	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 1	Homo sapiens (human)
Hsp70 protein binding	Cyclin-dependent kinase 1	Homo sapiens (human)
histone kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin-dependent protein kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
purine nucleobase binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
protein binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
ATP binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
glucose binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
glycogen phosphorylase activity	Glycogen phosphorylase, liver form	Homo sapiens (human)
AMP binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
vitamin binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
bile acid binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
identical protein binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
linear malto-oligosaccharide phosphorylase activity	Glycogen phosphorylase, liver form	Homo sapiens (human)
SHG alpha-glucan phosphorylase activity	Glycogen phosphorylase, liver form	Homo sapiens (human)
pyridoxal phosphate binding	Glycogen phosphorylase, liver form	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
microtubule binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
immunoglobulin receptor binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
phosphatidylinositol binding	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
adenine phosphoribosyltransferase activity	Adenine phosphoribosyltransferase	Homo sapiens (human)
protein binding	Adenine phosphoribosyltransferase	Homo sapiens (human)
AMP binding	Adenine phosphoribosyltransferase	Homo sapiens (human)
adenine binding	Adenine phosphoribosyltransferase	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Yes	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
enzyme binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
transmembrane transporter binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Yes	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
platelet-derived growth factor receptor binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
integrin binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
SH3 domain binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ubiquitin protein ligase binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
gamma-tubulin binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
glycosphingolipid binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
transmembrane transporter binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ephrin receptor binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
phosphoprotein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
scaffold protein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
phosphorylation-dependent protein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
phosphatidylinositol 3-kinase activator activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
calcium ion binding	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
protein binding	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
ATP binding	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
signaling receptor activity	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
G-protein alpha-subunit binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein tyrosine kinase activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin-like growth factor receptor activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin-like growth factor binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
ATP binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin-like growth factor I binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
identical protein binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor substrate binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein-containing complex binding	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein transporter activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor activity	Insulin-like growth factor 1 receptor	Homo sapiens (human)
RNA binding	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
GTP binding	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
ATP hydrolysis activity	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
signal recognition particle binding	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
GTPase activity	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
protein binding	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
ubiquinol-cytochrome-c reductase activity	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
heme binding	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
metal ion binding	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
protein tyrosine kinase activity	Hepatocyte growth factor receptor	Homo sapiens (human)
protein binding	Hepatocyte growth factor receptor	Homo sapiens (human)
ATP binding	Hepatocyte growth factor receptor	Homo sapiens (human)
semaphorin receptor activity	Hepatocyte growth factor receptor	Homo sapiens (human)
protein phosphatase binding	Hepatocyte growth factor receptor	Homo sapiens (human)
identical protein binding	Hepatocyte growth factor receptor	Homo sapiens (human)
molecular function activator activity	Hepatocyte growth factor receptor	Homo sapiens (human)
hepatocyte growth factor receptor activity	Hepatocyte growth factor receptor	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
lipid binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein tyrosine kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet activating factor receptor activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor beta-receptor activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
signaling receptor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
ATP binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
enzyme binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein kinase binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
vascular endothelial growth factor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
MAP kinase kinase kinase activity	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
protease binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein tyrosine kinase activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
stem cell factor receptor activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
ATP binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cytokine binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
SH2 domain binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein homodimerization activity	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
metal ion binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
growth factor binding	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
protein binding	Glycogen phosphorylase, brain form	Homo sapiens (human)
glycogen phosphorylase activity	Glycogen phosphorylase, brain form	Homo sapiens (human)
linear malto-oligosaccharide phosphorylase activity	Glycogen phosphorylase, brain form	Homo sapiens (human)
SHG alpha-glucan phosphorylase activity	Glycogen phosphorylase, brain form	Homo sapiens (human)
pyridoxal phosphate binding	Glycogen phosphorylase, brain form	Homo sapiens (human)
protein serine/threonine kinase activity	Breakpoint cluster region protein	Homo sapiens (human)
protein tyrosine kinase activity	Breakpoint cluster region protein	Homo sapiens (human)
guanyl-nucleotide exchange factor activity	Breakpoint cluster region protein	Homo sapiens (human)
GTPase activator activity	Breakpoint cluster region protein	Homo sapiens (human)
protein binding	Breakpoint cluster region protein	Homo sapiens (human)
ATP binding	Breakpoint cluster region protein	Homo sapiens (human)
protein serine kinase activity	Breakpoint cluster region protein	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
transcription factor binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
manganese ion binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
ribosomal small subunit binding	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
protein tyrosine kinase activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor receptor activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
protein binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
ATP binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
heparin binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
fibroblast growth factor binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
SH2 domain binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
identical protein binding	Fibroblast growth factor receptor 1	Homo sapiens (human)
protein homodimerization activity	Fibroblast growth factor receptor 1	Homo sapiens (human)
receptor-receptor interaction	Fibroblast growth factor receptor 1	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 4	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 4	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase regulator activity	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 4	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 4	Homo sapiens (human)
ATP:ADP antiporter activity	ADP/ATP translocase 3	Homo sapiens (human)
protein binding	ADP/ATP translocase 3	Homo sapiens (human)
nucleotide binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
DNA binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
RNA binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
IMP dehydrogenase activity	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
protein binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
metal ion binding	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
protein kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein kinase C binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
signaling receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
insulin receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
integrin binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ATP binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
phospholipase activator activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
enzyme binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
heme binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
nuclear estrogen receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
SH2 domain binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
phospholipase binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
transmembrane transporter binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cadherin binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ephrin receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ATPase binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
phosphoprotein binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
BMP receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
connexin binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
scaffold protein binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cAMP-dependent protein kinase inhibitor activity	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
protein binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cAMP-dependent protein kinase regulator activity	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
protein domain specific binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
ubiquitin protein ligase binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
protein kinase A catalytic subunit binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cAMP binding	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
MAP kinase kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
calcium ion binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
mitogen-activated protein kinase kinase binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein-containing complex binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
scaffold protein binding	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
MAP kinase kinase kinase activity	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
protein serine/threonine kinase activity	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
phosphorylase kinase activity	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
protein binding	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
calmodulin binding	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
ATP binding	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
enzyme binding	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
tau-protein kinase activity	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
dihydronicotinamide riboside quinone reductase activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
protein binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
zinc ion binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
electron transfer activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
oxidoreductase activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
oxidoreductase activity, acting on other nitrogenous compounds as donors	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
chloride ion binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
protein homodimerization activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
FAD binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
melatonin binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
resveratrol binding	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
NAD(P)H dehydrogenase (quinone) activity	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
protein kinase activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor alpha-receptor activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor receptor binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
ATP binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
vascular endothelial growth factor binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein homodimerization activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein-containing complex binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Fer	Homo sapiens (human)
epidermal growth factor receptor binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein phosphatase 1 binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
lipid binding	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Fer	Homo sapiens (human)
protein kinase activity	Protein kinase C alpha type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
calcium,diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
integrin binding	Protein kinase C alpha type	Homo sapiens (human)
protein binding	Protein kinase C alpha type	Homo sapiens (human)
ATP binding	Protein kinase C alpha type	Homo sapiens (human)
zinc ion binding	Protein kinase C alpha type	Homo sapiens (human)
enzyme binding	Protein kinase C alpha type	Homo sapiens (human)
histone H3T6 kinase activity	Protein kinase C alpha type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
diacylglycerol binding	Protein kinase C alpha type	Homo sapiens (human)
magnesium ion binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein serine/threonine kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
AMP-activated protein kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cAMP-dependent protein kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
ATP binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein kinase binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein domain specific binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
manganese ion binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
ubiquitin protein ligase binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein kinase A regulatory subunit binding	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
channel activator activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
protein serine kinase activity	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
protein binding	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
ATP binding	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
growth factor binding	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
placental growth factor receptor activity	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
protein binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
ATP binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
ATP hydrolysis activity	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
protein-macromolecule adaptor activity	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
5'-3' DNA helicase activity	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
metal ion binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
4 iron, 4 sulfur cluster binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
DNA helicase activity	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
damaged DNA binding	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase II subunit alpha'	Homo sapiens (human)
protein binding	Casein kinase II subunit alpha'	Homo sapiens (human)
ATP binding	Casein kinase II subunit alpha'	Homo sapiens (human)
protein serine kinase activity	Casein kinase II subunit alpha'	Homo sapiens (human)
GTPase activity	Ras-related protein Rab-6A	Homo sapiens (human)
protein binding	Ras-related protein Rab-6A	Homo sapiens (human)
GTP binding	Ras-related protein Rab-6A	Homo sapiens (human)
protein domain specific binding	Ras-related protein Rab-6A	Homo sapiens (human)
myosin V binding	Ras-related protein Rab-6A	Homo sapiens (human)
phosphoribosylaminoimidazole carboxylase activity	Multifunctional protein ADE2	Homo sapiens (human)
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	Multifunctional protein ADE2	Homo sapiens (human)
protein binding	Multifunctional protein ADE2	Homo sapiens (human)
ATP binding	Multifunctional protein ADE2	Homo sapiens (human)
identical protein binding	Multifunctional protein ADE2	Homo sapiens (human)
5-amino-4-imidazole carboxylate lyase activity	Multifunctional protein ADE2	Homo sapiens (human)
cadherin binding	Multifunctional protein ADE2	Homo sapiens (human)
protein serine/threonine kinase activity	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
AMP-activated protein kinase activity	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
cAMP-dependent protein kinase activity	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
protein binding	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
ATP binding	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
protein serine kinase activity	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
protein kinase A regulatory subunit binding	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
magnesium ion binding	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein serine/threonine kinase activity	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
AMP-activated protein kinase activity	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
cAMP-dependent protein kinase activity	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein binding	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
ATP binding	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
ubiquitin protein ligase binding	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
protein serine kinase activity	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
ferrochelatase activity	Ferrochelatase, mitochondrial	Homo sapiens (human)
protein binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
ferrous iron binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
heme binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
iron-responsive element binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
identical protein binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
protein homodimerization activity	Ferrochelatase, mitochondrial	Homo sapiens (human)
2 iron, 2 sulfur cluster binding	Ferrochelatase, mitochondrial	Homo sapiens (human)
protein kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
PDZ domain binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
peptide binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
identical protein binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein phosphatase 2A binding	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase JAK1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase JAK1	Homo sapiens (human)
growth hormone receptor binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
protein phosphatase binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
ubiquitin protein ligase binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
CCR5 chemokine receptor binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase JAK1	Homo sapiens (human)
histone kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
magnesium ion binding	Cyclin-dependent kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 2	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 2	Homo sapiens (human)
protein domain specific binding	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin-dependent protein kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 2	Homo sapiens (human)
protein kinase activity	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
G protein-coupled receptor kinase activity	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
protein binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
ATP binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
alpha-2A adrenergic receptor binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
Edg-2 lysophosphatidic acid receptor binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
beta-adrenergic receptor kinase activity	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
G protein-coupled receptor binding	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
RNA binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
RNA helicase activity	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
helicase activity	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
protein binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
ATP binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
ATP hydrolysis activity	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
protein domain specific binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cadherin binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
mRNA binding	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
phosphotyrosine residue binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
phosphatase binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 3	Homo sapiens (human)
DNA-binding transcription factor binding	Mitogen-activated protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
protein binding	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
ATP binding	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
tau protein binding	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
tau-protein kinase activity	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
protein serine kinase activity	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
deoxyadenosine kinase activity	Deoxycytidine kinase	Homo sapiens (human)
deoxycytidine kinase activity	Deoxycytidine kinase	Homo sapiens (human)
deoxyguanosine kinase activity	Deoxycytidine kinase	Homo sapiens (human)
ATP binding	Deoxycytidine kinase	Homo sapiens (human)
protein homodimerization activity	Deoxycytidine kinase	Homo sapiens (human)
cytidine kinase activity	Deoxycytidine kinase	Homo sapiens (human)
phosphotyrosine residue binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
DNA binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
phosphatase binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 1	Homo sapiens (human)
virus receptor activity	Ephrin type-A receptor 2	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Ephrin type-A receptor 2	Homo sapiens (human)
ephrin receptor activity	Ephrin type-A receptor 2	Homo sapiens (human)
protein binding	Ephrin type-A receptor 2	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 2	Homo sapiens (human)
growth factor binding	Ephrin type-A receptor 2	Homo sapiens (human)
cadherin binding	Ephrin type-A receptor 2	Homo sapiens (human)
molecular function activator activity	Ephrin type-A receptor 2	Homo sapiens (human)
amyloid-beta binding	Ephrin type-B receptor 2	Homo sapiens (human)
protein tyrosine kinase activity	Ephrin type-B receptor 2	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-B receptor 2	Homo sapiens (human)
signaling receptor binding	Ephrin type-B receptor 2	Homo sapiens (human)
protein binding	Ephrin type-B receptor 2	Homo sapiens (human)
ATP binding	Ephrin type-B receptor 2	Homo sapiens (human)
axon guidance receptor activity	Ephrin type-B receptor 2	Homo sapiens (human)
identical protein binding	Ephrin type-B receptor 2	Homo sapiens (human)
protein-containing complex binding	Ephrin type-B receptor 2	Homo sapiens (human)
protein tyrosine kinase activity	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
growth hormone receptor binding	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
protein binding	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
ATP binding	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
type 1 angiotensin receptor binding	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
nucleoside diphosphate kinase activity	UMP-CMP kinase	Homo sapiens (human)
uridine kinase activity	UMP-CMP kinase	Homo sapiens (human)
ATP binding	UMP-CMP kinase	Homo sapiens (human)
UMP kinase activity	UMP-CMP kinase	Homo sapiens (human)
CMP kinase activity	UMP-CMP kinase	Homo sapiens (human)
dCMP kinase activity	UMP-CMP kinase	Homo sapiens (human)
nucleoside monophosphate kinase activity	UMP-CMP kinase	Homo sapiens (human)
cytidylate kinase activity	UMP-CMP kinase	Homo sapiens (human)
RNA binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
serine-type endopeptidase inhibitor activity	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
protein binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
ATP binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
phosphatidylethanolamine binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
enzyme binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
protein kinase binding	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
magnesium ion binding	Wee1-like protein kinase	Homo sapiens (human)
protein tyrosine kinase activity	Wee1-like protein kinase	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Wee1-like protein kinase	Homo sapiens (human)
protein binding	Wee1-like protein kinase	Homo sapiens (human)
ATP binding	Wee1-like protein kinase	Homo sapiens (human)
heme oxygenase (decyclizing) activity	Heme oxygenase 2	Homo sapiens (human)
protein binding	Heme oxygenase 2	Homo sapiens (human)
metal ion binding	Heme oxygenase 2	Homo sapiens (human)
heme binding	Heme oxygenase 2	Homo sapiens (human)
virus receptor activity	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
phosphatidylserine binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
protein binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
myosin heavy chain binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
methionine adenosyltransferase activity	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
protein binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
ATP binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
small molecule binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
identical protein binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
metal ion binding	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
G protein-coupled receptor binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
ATPase activator activity	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
ATP binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
Hsp70 protein binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
Tat protein binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
ubiquitin protein ligase binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
metal ion binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
low-density lipoprotein particle receptor binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
unfolded protein binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein-folding chaperone binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
C3HC4-type RING finger domain binding	DnaJ homolog subfamily A member 1	Homo sapiens (human)
protein kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
calmodulin binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
phosphatidylinositol-3,4,5-trisphosphate binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
enzyme binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein kinase binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nitric-oxide synthase regulator activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase inhibitor activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
identical protein binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein homodimerization activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
phosphatidylinositol-3,4-bisphosphate binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
14-3-3 protein binding	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
potassium channel activator activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
protein binding	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
metal ion binding	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
molecular function activator activity	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
microtubule motor activity	Kinesin-1 heavy chain	Homo sapiens (human)
protein binding	Kinesin-1 heavy chain	Homo sapiens (human)
ATP binding	Kinesin-1 heavy chain	Homo sapiens (human)
microtubule binding	Kinesin-1 heavy chain	Homo sapiens (human)
identical protein binding	Kinesin-1 heavy chain	Homo sapiens (human)
protein-containing complex binding	Kinesin-1 heavy chain	Homo sapiens (human)
cadherin binding	Kinesin-1 heavy chain	Homo sapiens (human)
ATP hydrolysis activity	Kinesin-1 heavy chain	Homo sapiens (human)
plus-end-directed microtubule motor activity	Kinesin-1 heavy chain	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase TTK	Homo sapiens (human)
protein binding	Dual specificity protein kinase TTK	Homo sapiens (human)
ATP binding	Dual specificity protein kinase TTK	Homo sapiens (human)
identical protein binding	Dual specificity protein kinase TTK	Homo sapiens (human)
kinetochore binding	Dual specificity protein kinase TTK	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase TTK	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase TTK	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase TTK	Homo sapiens (human)
DNA helicase activity	DNA replication licensing factor MCM4	Homo sapiens (human)
single-stranded DNA binding	DNA replication licensing factor MCM4	Homo sapiens (human)
protein binding	DNA replication licensing factor MCM4	Homo sapiens (human)
ATP binding	DNA replication licensing factor MCM4	Homo sapiens (human)
ATP hydrolysis activity	DNA replication licensing factor MCM4	Homo sapiens (human)
single-stranded DNA helicase activity	DNA replication licensing factor MCM4	Homo sapiens (human)
microfilament motor activity	Myosin-10	Homo sapiens (human)
actin filament binding	Myosin-10	Homo sapiens (human)
microfilament motor activity	Myosin-10	Homo sapiens (human)
actin binding	Myosin-10	Homo sapiens (human)
protein binding	Myosin-10	Homo sapiens (human)
calmodulin binding	Myosin-10	Homo sapiens (human)
ATP binding	Myosin-10	Homo sapiens (human)
RNA stem-loop binding	Myosin-10	Homo sapiens (human)
ADP binding	Myosin-10	Homo sapiens (human)
mRNA 5'-UTR binding	Myosin-10	Homo sapiens (human)
actin filament binding	Myosin-10	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein binding	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
ATP binding	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
growth factor binding	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein phosphatase binding	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein homodimerization activity	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
protein tyrosine kinase activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
integrin binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
protein binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
ATP binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
coreceptor activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
growth factor binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
identical protein binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cadherin binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
Hsp90 protein binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
MAP-kinase scaffold activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
PDZ domain binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein serine/threonine kinase activator activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
metal ion binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
scaffold protein binding	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cytokine receptor activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
ATP binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
nuclear glucocorticoid receptor binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein-containing complex binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
phosphatidylinositol 3-kinase activator activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
growth factor binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein serine/threonine kinase activity	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
transforming growth factor beta receptor activity, type I	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
protein binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
ATP binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
BMP binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
protein homodimerization activity	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
SMAD binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
metal ion binding	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
BMP receptor activity	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
activin receptor activity	Activin receptor type-1B	Homo sapiens (human)
growth factor binding	Activin receptor type-1B	Homo sapiens (human)
activin binding	Activin receptor type-1B	Homo sapiens (human)
protein serine/threonine kinase activity	Activin receptor type-1B	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Activin receptor type-1B	Homo sapiens (human)
protein binding	Activin receptor type-1B	Homo sapiens (human)
ATP binding	Activin receptor type-1B	Homo sapiens (human)
activin receptor activity, type I	Activin receptor type-1B	Homo sapiens (human)
activin receptor activity	Activin receptor type-1B	Homo sapiens (human)
ubiquitin protein ligase binding	Activin receptor type-1B	Homo sapiens (human)
inhibin binding	Activin receptor type-1B	Homo sapiens (human)
SMAD binding	Activin receptor type-1B	Homo sapiens (human)
metal ion binding	Activin receptor type-1B	Homo sapiens (human)
I-SMAD binding	Activin receptor type-1B	Homo sapiens (human)
transforming growth factor beta receptor activity	TGF-beta receptor type-1	Homo sapiens (human)
growth factor binding	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta binding	TGF-beta receptor type-1	Homo sapiens (human)
protein kinase activity	TGF-beta receptor type-1	Homo sapiens (human)
protein serine/threonine kinase activity	TGF-beta receptor type-1	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor activity	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor activity, type I	TGF-beta receptor type-1	Homo sapiens (human)
type II transforming growth factor beta receptor binding	TGF-beta receptor type-1	Homo sapiens (human)
protein binding	TGF-beta receptor type-1	Homo sapiens (human)
ATP binding	TGF-beta receptor type-1	Homo sapiens (human)
ubiquitin protein ligase binding	TGF-beta receptor type-1	Homo sapiens (human)
SMAD binding	TGF-beta receptor type-1	Homo sapiens (human)
metal ion binding	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta binding	TGF-beta receptor type-1	Homo sapiens (human)
I-SMAD binding	TGF-beta receptor type-1	Homo sapiens (human)
activin receptor activity, type I	TGF-beta receptor type-1	Homo sapiens (human)
activin binding	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta binding	TGF-beta receptor type-2	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta receptor activity	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta receptor activity, type II	TGF-beta receptor type-2	Homo sapiens (human)
protein binding	TGF-beta receptor type-2	Homo sapiens (human)
ATP binding	TGF-beta receptor type-2	Homo sapiens (human)
glycosaminoglycan binding	TGF-beta receptor type-2	Homo sapiens (human)
kinase activator activity	TGF-beta receptor type-2	Homo sapiens (human)
type I transforming growth factor beta receptor binding	TGF-beta receptor type-2	Homo sapiens (human)
SMAD binding	TGF-beta receptor type-2	Homo sapiens (human)
metal ion binding	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta binding	TGF-beta receptor type-2	Homo sapiens (human)
molecular adaptor activity	TGF-beta receptor type-2	Homo sapiens (human)
activin receptor activity	TGF-beta receptor type-2	Homo sapiens (human)
activin binding	TGF-beta receptor type-2	Homo sapiens (human)
protein serine/threonine kinase activity	TGF-beta receptor type-2	Homo sapiens (human)
protein binding	Electron transfer flavoprotein subunit beta	Homo sapiens (human)
electron transfer activity	Electron transfer flavoprotein subunit beta	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein phosphatase binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein kinase A catalytic subunit binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
proline-rich region binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein tyrosine kinase binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase CSK	Homo sapiens (human)
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity	Glycine--tRNA ligase	Homo sapiens (human)
glycine-tRNA ligase activity	Glycine--tRNA ligase	Homo sapiens (human)
protein binding	Glycine--tRNA ligase	Homo sapiens (human)
ATP binding	Glycine--tRNA ligase	Homo sapiens (human)
transferase activity	Glycine--tRNA ligase	Homo sapiens (human)
identical protein binding	Glycine--tRNA ligase	Homo sapiens (human)
protein dimerization activity	Glycine--tRNA ligase	Homo sapiens (human)
protein kinase activity	Protein kinase C iota type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C iota type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C iota type	Homo sapiens (human)
protein binding	Protein kinase C iota type	Homo sapiens (human)
ATP binding	Protein kinase C iota type	Homo sapiens (human)
phospholipid binding	Protein kinase C iota type	Homo sapiens (human)
metal ion binding	Protein kinase C iota type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C iota type	Homo sapiens (human)
RNA binding	Exosome RNA helicase MTR4	Homo sapiens (human)
RNA helicase activity	Exosome RNA helicase MTR4	Homo sapiens (human)
protein binding	Exosome RNA helicase MTR4	Homo sapiens (human)
ATP binding	Exosome RNA helicase MTR4	Homo sapiens (human)
ATP hydrolysis activity	Exosome RNA helicase MTR4	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Tec	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Tec	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Tec	Homo sapiens (human)
phospholipid binding	Tyrosine-protein kinase Tec	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase Tec	Homo sapiens (human)
magnesium ion binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
actin monomer binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein kinase activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
manganese ion binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
actin filament binding	Tyrosine-protein kinase ABL2	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase FRK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase FRK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase FRK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase FRK	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase FRK	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein serine/threonine kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
integrin binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
interleukin-15 receptor binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
kinase activity	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein kinase binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
phosphatase binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
Toll-like receptor binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
SH2 domain binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
scaffold protein binding	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein binding	26S proteasome regulatory subunit 6B	Homo sapiens (human)
ATP binding	26S proteasome regulatory subunit 6B	Homo sapiens (human)
ATP hydrolysis activity	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteasome-activating activity	26S proteasome regulatory subunit 6B	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
JUN kinase activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
enzyme binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein phosphatase binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
histone deacetylase regulator activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
histone deacetylase binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein serine/threonine kinase binding	Mitogen-activated protein kinase 8	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 9	Homo sapiens (human)
JUN kinase activity	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 9	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 9	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein kinase binding	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
protein binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
ATP binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 5-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
1-phosphatidylinositol-5-phosphate 4-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
protein homodimerization activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
protein kinase activity	Casein kinase I isoform alpha	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform alpha	Homo sapiens (human)
protein binding	Casein kinase I isoform alpha	Homo sapiens (human)
ATP binding	Casein kinase I isoform alpha	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform alpha	Homo sapiens (human)
protein kinase activity	Casein kinase I isoform delta	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform delta	Homo sapiens (human)
protein binding	Casein kinase I isoform delta	Homo sapiens (human)
ATP binding	Casein kinase I isoform delta	Homo sapiens (human)
cadherin binding	Casein kinase I isoform delta	Homo sapiens (human)
tau-protein kinase activity	Casein kinase I isoform delta	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform delta	Homo sapiens (human)
protein kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein binding	MAP kinase-activated protein kinase 2	Homo sapiens (human)
ATP binding	MAP kinase-activated protein kinase 2	Homo sapiens (human)
protein serine kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
calcium-dependent protein serine/threonine kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
calmodulin binding	MAP kinase-activated protein kinase 2	Homo sapiens (human)
calmodulin-dependent protein kinase activity	MAP kinase-activated protein kinase 2	Homo sapiens (human)
mitogen-activated protein kinase binding	MAP kinase-activated protein kinase 2	Homo sapiens (human)
RNA binding	Elongation factor Tu, mitochondrial	Homo sapiens (human)
translation elongation factor activity	Elongation factor Tu, mitochondrial	Homo sapiens (human)
GTPase activity	Elongation factor Tu, mitochondrial	Homo sapiens (human)
protein binding	Elongation factor Tu, mitochondrial	Homo sapiens (human)
GTP binding	Elongation factor Tu, mitochondrial	Homo sapiens (human)
tRNA binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cysteine-tRNA ligase activity	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
protein binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
ATP binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
identical protein binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
metal ion binding	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
RNA binding	Casein kinase I isoform epsilon	Homo sapiens (human)
protein kinase activity	Casein kinase I isoform epsilon	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform epsilon	Homo sapiens (human)
protein binding	Casein kinase I isoform epsilon	Homo sapiens (human)
ATP binding	Casein kinase I isoform epsilon	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform epsilon	Homo sapiens (human)
acyl-CoA dehydrogenase activity	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
long-chain fatty acyl-CoA dehydrogenase activity	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
protein binding	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
very-long-chain fatty acyl-CoA dehydrogenase activity	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
identical protein binding	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
flavin adenine dinucleotide binding	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
fatty-acyl-CoA binding	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein binding	Dual specificity protein kinase CLK1	Homo sapiens (human)
ATP binding	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase CLK1	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein binding	Dual specificity protein kinase CLK2	Homo sapiens (human)
ATP binding	Dual specificity protein kinase CLK2	Homo sapiens (human)
identical protein binding	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase CLK2	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase CLK2	Homo sapiens (human)
RNA binding	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein binding	Dual specificity protein kinase CLK3	Homo sapiens (human)
ATP binding	Dual specificity protein kinase CLK3	Homo sapiens (human)
identical protein binding	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase CLK3	Homo sapiens (human)
protein serine/threonine kinase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
signaling receptor binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protein binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
ATP binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protein kinase A catalytic subunit binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
tau protein binding	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
tau-protein kinase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protein serine kinase activity	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
protease binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
p53 binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein serine/threonine kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
ATP binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
beta-catenin binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein kinase binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
ubiquitin protein ligase binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein kinase A catalytic subunit binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
dynactin binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
tau protein binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
tau-protein kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
NF-kappaB binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor binding	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein serine kinase activity	Glycogen synthase kinase-3 beta	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 7	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 7	Homo sapiens (human)
ATP-dependent activity, acting on DNA	Cyclin-dependent kinase 7	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 7	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription coactivator binding	Cyclin-dependent kinase 9	Homo sapiens (human)
DNA binding	Cyclin-dependent kinase 9	Homo sapiens (human)
chromatin binding	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription elongation factor activity	Cyclin-dependent kinase 9	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 9	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 9	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
protein kinase binding	Cyclin-dependent kinase 9	Homo sapiens (human)
7SK snRNA binding	Cyclin-dependent kinase 9	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 9	Homo sapiens (human)
GTPase activity	Ras-related protein Rab-27A	Homo sapiens (human)
G protein activity	Ras-related protein Rab-27A	Homo sapiens (human)
protein binding	Ras-related protein Rab-27A	Homo sapiens (human)
GTP binding	Ras-related protein Rab-27A	Homo sapiens (human)
GDP binding	Ras-related protein Rab-27A	Homo sapiens (human)
protein domain specific binding	Ras-related protein Rab-27A	Homo sapiens (human)
myosin V binding	Ras-related protein Rab-27A	Homo sapiens (human)
protein kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
ATP binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein kinase binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
heat shock protein binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
identical protein binding	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein homodimerization activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein heterodimerization activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein serine kinase activity	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein kinase activity	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein kinase binding	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein phosphatase binding	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
protein kinase binding	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
microtubule binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
anaphase-promoting complex binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
protein kinase activity	LIM domain kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	LIM domain kinase 1	Homo sapiens (human)
protein binding	LIM domain kinase 1	Homo sapiens (human)
ATP binding	LIM domain kinase 1	Homo sapiens (human)
heat shock protein binding	LIM domain kinase 1	Homo sapiens (human)
metal ion binding	LIM domain kinase 1	Homo sapiens (human)
protein serine kinase activity	LIM domain kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	LIM domain kinase 2	Homo sapiens (human)
protein binding	LIM domain kinase 2	Homo sapiens (human)
ATP binding	LIM domain kinase 2	Homo sapiens (human)
metal ion binding	LIM domain kinase 2	Homo sapiens (human)
protein serine kinase activity	LIM domain kinase 2	Homo sapiens (human)
JUN kinase activity	Mitogen-activated protein kinase 10	Homo sapiens (human)
MAP kinase kinase activity	Mitogen-activated protein kinase 10	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 10	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 10	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 10	Homo sapiens (human)
tRNA binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
RNA binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
tyrosine-tRNA ligase activity	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
interleukin-8 receptor binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
protein binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
ATP binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
small molecule binding	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
protein kinase activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cAMP-dependent protein kinase activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
protein binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
ATP binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cAMP-dependent protein kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
AMP binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
protein kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
protein kinase binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
ADP binding	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
ephrin receptor activity	Ephrin type-B receptor 3	Homo sapiens (human)
protein binding	Ephrin type-B receptor 3	Homo sapiens (human)
ATP binding	Ephrin type-B receptor 3	Homo sapiens (human)
axon guidance receptor activity	Ephrin type-B receptor 3	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-B receptor 3	Homo sapiens (human)
ephrin receptor activity	Ephrin type-A receptor 5	Homo sapiens (human)
GPI-linked ephrin receptor activity	Ephrin type-A receptor 5	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 5	Homo sapiens (human)
protein binding	Ephrin type-A receptor 5	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 5	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Ephrin type-B receptor 4	Homo sapiens (human)
ephrin receptor activity	Ephrin type-B receptor 4	Homo sapiens (human)
protein binding	Ephrin type-B receptor 4	Homo sapiens (human)
ATP binding	Ephrin type-B receptor 4	Homo sapiens (human)
amyloid-beta binding	Ephrin type-A receptor 4	Homo sapiens (human)
protein kinase activity	Ephrin type-A receptor 4	Homo sapiens (human)
protein tyrosine kinase activity	Ephrin type-A receptor 4	Homo sapiens (human)
GPI-linked ephrin receptor activity	Ephrin type-A receptor 4	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 4	Homo sapiens (human)
protein binding	Ephrin type-A receptor 4	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 4	Homo sapiens (human)
kinase activity	Ephrin type-A receptor 4	Homo sapiens (human)
PH domain binding	Ephrin type-A receptor 4	Homo sapiens (human)
identical protein binding	Ephrin type-A receptor 4	Homo sapiens (human)
ephrin receptor binding	Ephrin type-A receptor 4	Homo sapiens (human)
DH domain binding	Ephrin type-A receptor 4	Homo sapiens (human)
protein tyrosine kinase binding	Ephrin type-A receptor 4	Homo sapiens (human)
adenylate kinase activity	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
protein binding	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
ATP binding	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
RNA binding	Adenosine kinase	Homo sapiens (human)
deoxyadenosine kinase activity	Adenosine kinase	Homo sapiens (human)
ATP binding	Adenosine kinase	Homo sapiens (human)
metal ion binding	Adenosine kinase	Homo sapiens (human)
adenosine kinase activity	Adenosine kinase	Homo sapiens (human)
G protein activity	Ras-related protein Rab-10	Homo sapiens (human)
protein binding	Ras-related protein Rab-10	Homo sapiens (human)
GTP binding	Ras-related protein Rab-10	Homo sapiens (human)
GDP binding	Ras-related protein Rab-10	Homo sapiens (human)
myosin V binding	Ras-related protein Rab-10	Homo sapiens (human)
cadherin binding involved in cell-cell adhesion	Ras-related protein Rab-10	Homo sapiens (human)
actin filament binding	Actin-related protein 3	Homo sapiens (human)
structural constituent of cytoskeleton	Actin-related protein 3	Homo sapiens (human)
protein binding	Actin-related protein 3	Homo sapiens (human)
ATP binding	Actin-related protein 3	Homo sapiens (human)
actin filament binding	Actin-related protein 2	Homo sapiens (human)
structural constituent of cytoskeleton	Actin-related protein 2	Homo sapiens (human)
protein binding	Actin-related protein 2	Homo sapiens (human)
ATP binding	Actin-related protein 2	Homo sapiens (human)
nuclear export signal receptor activity	GTP-binding nuclear protein Ran	Homo sapiens (human)
pre-miRNA binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
magnesium ion binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
chromatin binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
RNA binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
GTPase activity	GTP-binding nuclear protein Ran	Homo sapiens (human)
G protein activity	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
GTP binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
GDP binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein domain specific binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
cadherin binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
dynein intermediate chain binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein heterodimerization activity	GTP-binding nuclear protein Ran	Homo sapiens (human)
importin-alpha family protein binding	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform gamma-2	Homo sapiens (human)
protein binding	Casein kinase I isoform gamma-2	Homo sapiens (human)
ATP binding	Casein kinase I isoform gamma-2	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform gamma-2	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 3	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 3	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 3	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 3	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 3	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 6	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 6	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 6	Homo sapiens (human)
FBXO family protein binding	Cyclin-dependent kinase 6	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 6	Homo sapiens (human)
microtubule binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
p53 binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
ErbB-2 class receptor binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
ATP binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
acetylcholine receptor activator activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
ErbB-3 class receptor binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
tau protein binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
tau-protein kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
Hsp90 protein binding	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 16	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 16	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 16	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 16	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 16	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 17	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 17	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 17	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 17	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 17	Homo sapiens (human)
6-phosphofructokinase activity	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
protein binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
protein-containing complex binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
cadherin binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
metal ion binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
ATP binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
monosaccharide binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
AMP binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
identical protein binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
fructose-6-phosphate binding	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
protein kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
MAP-kinase scaffold activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein kinase activator activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein serine/threonine kinase activator activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
scaffold protein binding	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
protein kinase activity	Angiopoietin-1 receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Angiopoietin-1 receptor	Homo sapiens (human)
protein binding	Angiopoietin-1 receptor	Homo sapiens (human)
ATP binding	Angiopoietin-1 receptor	Homo sapiens (human)
growth factor binding	Angiopoietin-1 receptor	Homo sapiens (human)
signaling receptor activity	Angiopoietin-1 receptor	Homo sapiens (human)
identical protein binding	Angiopoietin-1 receptor	Homo sapiens (human)
DNA binding	DNA topoisomerase 2-beta	Homo sapiens (human)
chromatin binding	DNA topoisomerase 2-beta	Homo sapiens (human)
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	DNA topoisomerase 2-beta	Homo sapiens (human)
protein binding	DNA topoisomerase 2-beta	Homo sapiens (human)
ATP binding	DNA topoisomerase 2-beta	Homo sapiens (human)
ribonucleoprotein complex binding	DNA topoisomerase 2-beta	Homo sapiens (human)
metal ion binding	DNA topoisomerase 2-beta	Homo sapiens (human)
protein kinase activity	Protein kinase C theta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C theta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C theta type	Homo sapiens (human)
protein binding	Protein kinase C theta type	Homo sapiens (human)
ATP binding	Protein kinase C theta type	Homo sapiens (human)
metal ion binding	Protein kinase C theta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C theta type	Homo sapiens (human)
activin receptor activity, type I	Activin receptor type-1	Homo sapiens (human)
protein kinase activity	Activin receptor type-1	Homo sapiens (human)
protein serine/threonine kinase activity	Activin receptor type-1	Homo sapiens (human)
transmembrane receptor protein serine/threonine kinase activity	Activin receptor type-1	Homo sapiens (human)
protein binding	Activin receptor type-1	Homo sapiens (human)
ATP binding	Activin receptor type-1	Homo sapiens (human)
peptide hormone binding	Activin receptor type-1	Homo sapiens (human)
protein homodimerization activity	Activin receptor type-1	Homo sapiens (human)
cadherin binding	Activin receptor type-1	Homo sapiens (human)
SMAD binding	Activin receptor type-1	Homo sapiens (human)
metal ion binding	Activin receptor type-1	Homo sapiens (human)
activin binding	Activin receptor type-1	Homo sapiens (human)
transforming growth factor beta binding	Activin receptor type-1	Homo sapiens (human)
BMP receptor activity	Activin receptor type-1	Homo sapiens (human)
protein tyrosine kinase binding	Activin receptor type-1	Homo sapiens (human)
transforming growth factor beta receptor activity, type I	Activin receptor type-1	Homo sapiens (human)
macrophage colony-stimulating factor receptor activity	Macrophage-stimulating protein receptor	Homo sapiens (human)
protein binding	Macrophage-stimulating protein receptor	Homo sapiens (human)
ATP binding	Macrophage-stimulating protein receptor	Homo sapiens (human)
enzyme binding	Macrophage-stimulating protein receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Macrophage-stimulating protein receptor	Homo sapiens (human)
actin binding	Focal adhesion kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Focal adhesion kinase 1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Focal adhesion kinase 1	Homo sapiens (human)
protein tyrosine phosphatase activity	Focal adhesion kinase 1	Homo sapiens (human)
integrin binding	Focal adhesion kinase 1	Homo sapiens (human)
protein binding	Focal adhesion kinase 1	Homo sapiens (human)
ATP binding	Focal adhesion kinase 1	Homo sapiens (human)
JUN kinase binding	Focal adhesion kinase 1	Homo sapiens (human)
protein kinase binding	Focal adhesion kinase 1	Homo sapiens (human)
protein phosphatase binding	Focal adhesion kinase 1	Homo sapiens (human)
SH2 domain binding	Focal adhesion kinase 1	Homo sapiens (human)
molecular function activator activity	Focal adhesion kinase 1	Homo sapiens (human)
protein kinase activity	Protein kinase C zeta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C zeta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C zeta type	Homo sapiens (human)
protein binding	Protein kinase C zeta type	Homo sapiens (human)
ATP binding	Protein kinase C zeta type	Homo sapiens (human)
potassium channel regulator activity	Protein kinase C zeta type	Homo sapiens (human)
protein kinase binding	Protein kinase C zeta type	Homo sapiens (human)
phospholipase binding	Protein kinase C zeta type	Homo sapiens (human)
insulin receptor substrate binding	Protein kinase C zeta type	Homo sapiens (human)
protein-containing complex binding	Protein kinase C zeta type	Homo sapiens (human)
metal ion binding	Protein kinase C zeta type	Homo sapiens (human)
14-3-3 protein binding	Protein kinase C zeta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C zeta type	Homo sapiens (human)
protein kinase activity	Protein kinase C delta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C delta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C delta type	Homo sapiens (human)
diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	Protein kinase C delta type	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Protein kinase C delta type	Homo sapiens (human)
protein binding	Protein kinase C delta type	Homo sapiens (human)
ATP binding	Protein kinase C delta type	Homo sapiens (human)
enzyme activator activity	Protein kinase C delta type	Homo sapiens (human)
enzyme binding	Protein kinase C delta type	Homo sapiens (human)
protein kinase binding	Protein kinase C delta type	Homo sapiens (human)
insulin receptor substrate binding	Protein kinase C delta type	Homo sapiens (human)
metal ion binding	Protein kinase C delta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C delta type	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase BTK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase BTK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
phosphatidylinositol-3,4,5-trisphosphate binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
phospholipase activator activity	Tyrosine-protein kinase BTK	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase BTK	Homo sapiens (human)
protein serine/threonine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
GTPase inhibitor activity	Activated CDC42 kinase 1	Homo sapiens (human)
epidermal growth factor receptor binding	Activated CDC42 kinase 1	Homo sapiens (human)
protein binding	Activated CDC42 kinase 1	Homo sapiens (human)
ATP binding	Activated CDC42 kinase 1	Homo sapiens (human)
ubiquitin protein ligase binding	Activated CDC42 kinase 1	Homo sapiens (human)
identical protein binding	Activated CDC42 kinase 1	Homo sapiens (human)
metal ion binding	Activated CDC42 kinase 1	Homo sapiens (human)
WW domain binding	Activated CDC42 kinase 1	Homo sapiens (human)
protein serine kinase activity	Activated CDC42 kinase 1	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
protein binding	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
collagen binding	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
ATP binding	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
protein tyrosine kinase collagen receptor activity	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
metal ion binding	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
transcription cis-regulatory region binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
inward rectifier potassium channel activity	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
voltage-gated potassium channel activity	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
delayed rectifier potassium channel activity	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
protein binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
ubiquitin protein ligase binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
identical protein binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
protein homodimerization activity	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
C3HC4-type RING finger domain binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
scaffold protein binding	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
mitogen-activated protein kinase kinase kinase binding	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein serine/threonine kinase activator activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor binding	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 4	Homo sapiens (human)
chromatin binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein serine/threonine kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
AMP-activated protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cAMP-dependent protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
ATP binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
metal ion binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
tau protein binding	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
tau-protein kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein serine kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
histone H2BS36 kinase activity	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
protein kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
protein binding	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
ATP binding	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
metal ion binding	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
protein serine kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
MAP kinase kinase activity	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 7	Homo sapiens (human)
enzyme inhibitor activity	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 7	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 7	Homo sapiens (human)
mitogen-activated protein kinase binding	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 7	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein tyrosine kinase activator activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activator activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
zinc ion binding	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Integrin-linked protein kinase	Homo sapiens (human)
protein binding	Integrin-linked protein kinase	Homo sapiens (human)
ATP binding	Integrin-linked protein kinase	Homo sapiens (human)
protein kinase binding	Integrin-linked protein kinase	Homo sapiens (human)
protein serine kinase activity	Integrin-linked protein kinase	Homo sapiens (human)
protein kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
protein binding	Rho-associated protein kinase 1	Homo sapiens (human)
ATP binding	Rho-associated protein kinase 1	Homo sapiens (human)
small GTPase binding	Rho-associated protein kinase 1	Homo sapiens (human)
metal ion binding	Rho-associated protein kinase 1	Homo sapiens (human)
tau protein binding	Rho-associated protein kinase 1	Homo sapiens (human)
tau-protein kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
Rho-dependent protein serine/threonine kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
protein serine kinase activity	Rho-associated protein kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
protein binding	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
ATP binding	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
calcium-dependent protein serine/threonine phosphatase activity	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
identical protein binding	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
protein homodimerization activity	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
protein serine/threonine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
sodium channel inhibitor activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
titin binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
identical protein binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein homodimerization activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
transmembrane transporter binding	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
protein kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
ATP binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
identical protein binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
tau protein binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
tau-protein kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
protein serine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
histone H3T45 kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
transcription coactivator activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
activin receptor activity, type II	Activin receptor type-2B	Homo sapiens (human)
protein serine/threonine kinase activity	Activin receptor type-2B	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Activin receptor type-2B	Homo sapiens (human)
protein binding	Activin receptor type-2B	Homo sapiens (human)
ATP binding	Activin receptor type-2B	Homo sapiens (human)
activin receptor activity, type II	Activin receptor type-2B	Homo sapiens (human)
kinase activator activity	Activin receptor type-2B	Homo sapiens (human)
growth factor binding	Activin receptor type-2B	Homo sapiens (human)
metal ion binding	Activin receptor type-2B	Homo sapiens (human)
activin binding	Activin receptor type-2B	Homo sapiens (human)
activin receptor activity	Activin receptor type-2B	Homo sapiens (human)
protein binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
ATP binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
activin receptor activity, type II	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
growth factor binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
BMP binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cadherin binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
metal ion binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
BMP receptor activity	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
protein tyrosine kinase binding	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
transforming growth factor beta receptor activity	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
protein tyrosine kinase activity	Protein-tyrosine kinase 6	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Protein-tyrosine kinase 6	Homo sapiens (human)
protein binding	Protein-tyrosine kinase 6	Homo sapiens (human)
ATP binding	Protein-tyrosine kinase 6	Homo sapiens (human)
identical protein binding	Protein-tyrosine kinase 6	Homo sapiens (human)
signaling receptor binding	Protein-tyrosine kinase 6	Homo sapiens (human)
protein kinase activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
cGMP-dependent protein kinase activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
calcium channel regulator activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
protein binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
ATP binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
cGMP binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
identical protein binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
mitogen-activated protein kinase p38 binding	cGMP-dependent protein kinase 1	Homo sapiens (human)
protein serine kinase activity	cGMP-dependent protein kinase 1	Homo sapiens (human)
RNA binding	Cyclin-dependent kinase 13	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 13	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 13	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 13	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 13	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 13	Homo sapiens (human)
protein kinase binding	Cyclin-dependent kinase 13	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 13	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 13	Homo sapiens (human)
K63-linked polyubiquitin modification-dependent protein binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
protein serine/threonine kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
protein binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
ATP binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
IkappaB kinase activity	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
protein phosphatase binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
ubiquitin protein ligase binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
K48-linked polyubiquitin modification-dependent protein binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
identical protein binding	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein tyrosine kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
ATP binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
ubiquitin protein ligase binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
glutamate receptor binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
3-phosphoinositide-dependent protein kinase binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein-containing complex binding	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
neurotransmitter receptor regulator activity	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
protein serine/threonine kinase activity	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
calcium ion binding	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
protein binding	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
ATP binding	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
lipid binding	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
protein serine kinase activity	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
chromatin binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
RNA binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
protein binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
ATP binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
ATP hydrolysis activity	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mediator complex binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
protein heterodimerization activity	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
DNA binding	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nucleosomal DNA binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
transcription coregulator binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
transcription corepressor activity	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
helicase activity	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
protein binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
ATP binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
zinc ion binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
ATP hydrolysis activity	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
histone deacetylase binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
ATP-dependent chromatin remodeler activity	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
chromatin binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
DNA binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
histone binding	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
acyl-CoA oxidase activity	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
protein binding	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
PDZ domain binding	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
protein homodimerization activity	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
FAD binding	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
fatty acid binding	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
flavin adenine dinucleotide binding	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
palmitoyl-CoA oxidase activity	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
protein tyrosine kinase activity	Ephrin type-A receptor 7	Homo sapiens (human)
GPI-linked ephrin receptor activity	Ephrin type-A receptor 7	Homo sapiens (human)
protein binding	Ephrin type-A receptor 7	Homo sapiens (human)
ATP binding	Ephrin type-A receptor 7	Homo sapiens (human)
axon guidance receptor activity	Ephrin type-A receptor 7	Homo sapiens (human)
growth factor binding	Ephrin type-A receptor 7	Homo sapiens (human)
chemorepellent activity	Ephrin type-A receptor 7	Homo sapiens (human)
transmembrane-ephrin receptor activity	Ephrin type-A receptor 7	Homo sapiens (human)
delta24(24-1) sterol reductase activity	Delta(24)-sterol reductase	Homo sapiens (human)
protein binding	Delta(24)-sterol reductase	Homo sapiens (human)
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	Delta(24)-sterol reductase	Homo sapiens (human)
enzyme binding	Delta(24)-sterol reductase	Homo sapiens (human)
peptide antigen binding	Delta(24)-sterol reductase	Homo sapiens (human)
delta24-sterol reductase activity	Delta(24)-sterol reductase	Homo sapiens (human)
FAD binding	Delta(24)-sterol reductase	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein serine/threonine kinase activity	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
actin binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
myosin light chain kinase activity	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
protein binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
calmodulin binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
ATP binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
metal ion binding	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 11	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 11	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 11	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 11	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 11	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
p53 binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
LRR domain binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein kinase activator activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein-containing complex binding	Serine/threonine-protein kinase STK11	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase STK11	Homo sapiens (human)
structural constituent of cytoskeleton	Coiled-coil domain-containing protein 6	Homo sapiens (human)
protein binding	Coiled-coil domain-containing protein 6	Homo sapiens (human)
SH3 domain binding	Coiled-coil domain-containing protein 6	Homo sapiens (human)
identical protein binding	Coiled-coil domain-containing protein 6	Homo sapiens (human)
chromatin binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein kinase C binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
nuclear receptor coactivator activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
histone H3T11 kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
histone binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
histone deacetylase binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
nuclear androgen receptor binding	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase N1	Homo sapiens (human)
RNA binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
histone deacetylase binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
RNA polymerase binding	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
MAP kinase kinase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
enzyme binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
protein phosphatase binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
mitogen-activated protein kinase p38 binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
NFAT protein binding	Mitogen-activated protein kinase 14	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 14	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
calcium-dependent protein serine/threonine kinase activity	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
small GTPase binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
mitogen-activated protein kinase kinase binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
mitogen-activated protein kinase kinase kinase binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein homodimerization activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein binding	Discoidin domain-containing receptor 2	Homo sapiens (human)
collagen binding	Discoidin domain-containing receptor 2	Homo sapiens (human)
ATP binding	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein tyrosine kinase collagen receptor activity	Discoidin domain-containing receptor 2	Homo sapiens (human)
protein serine/threonine kinase activity	AP2-associated protein kinase 1	Homo sapiens (human)
Notch binding	AP2-associated protein kinase 1	Homo sapiens (human)
protein binding	AP2-associated protein kinase 1	Homo sapiens (human)
ATP binding	AP2-associated protein kinase 1	Homo sapiens (human)
AP-2 adaptor complex binding	AP2-associated protein kinase 1	Homo sapiens (human)
protein serine kinase activity	AP2-associated protein kinase 1	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Myosin light chain kinase 3	Homo sapiens (human)
myosin light chain kinase activity	Myosin light chain kinase 3	Homo sapiens (human)
protein binding	Myosin light chain kinase 3	Homo sapiens (human)
ATP binding	Myosin light chain kinase 3	Homo sapiens (human)
molecular_function	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
ATP hydrolysis activity	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
ATP-dependent protein folding chaperone	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
disordered domain specific binding	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
ATP binding	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
unfolded protein binding	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
protein binding	Rab-like protein 3	Homo sapiens (human)
GTP binding	Rab-like protein 3	Homo sapiens (human)
protein homodimerization activity	Rab-like protein 3	Homo sapiens (human)
GTPase activity	Rab-like protein 3	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
flavin adenine dinucleotide binding	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
long-chain fatty acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
protein binding	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
very-long-chain fatty acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
flavin adenine dinucleotide binding	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
medium-chain fatty acyl-CoA dehydrogenase activity	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
endonuclease activity	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
RNA endonuclease activity	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
unfolded protein binding	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
RNA binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
lipid binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein kinase activator activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
tau protein binding	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
chromatin binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
RNA binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
RNA helicase activity	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
double-stranded RNA binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
protein binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
ATP binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
ATP hydrolysis activity	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
G-quadruplex RNA binding	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
DNA helicase activity	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
transferase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
alpha-tubulin binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein serine/threonine kinase activator activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
tau protein binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
beta-tubulin binding	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
protein kinase activity	STE20-related kinase adapter protein alpha	Homo sapiens (human)
protein binding	STE20-related kinase adapter protein alpha	Homo sapiens (human)
ATP binding	STE20-related kinase adapter protein alpha	Homo sapiens (human)
kinase binding	STE20-related kinase adapter protein alpha	Homo sapiens (human)
protein kinase activator activity	STE20-related kinase adapter protein alpha	Homo sapiens (human)
protein serine/threonine kinase activator activity	STE20-related kinase adapter protein alpha	Homo sapiens (human)
microfilament motor activity	Myosin-14	Homo sapiens (human)
actin filament binding	Myosin-14	Homo sapiens (human)
calmodulin binding	Myosin-14	Homo sapiens (human)
ATP binding	Myosin-14	Homo sapiens (human)
protein serine/threonine kinase activity	AarF domain-containing protein kinase 1	Homo sapiens (human)
ATP binding	AarF domain-containing protein kinase 1	Homo sapiens (human)
RNA binding	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
RNA helicase activity	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
protein binding	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
ATP binding	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
ATP hydrolysis activity	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
p53 binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
MAP kinase kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
ATP binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein serine kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
calmodulin-dependent protein kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
mitogen-activated protein kinase binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
calcium-dependent protein serine/threonine kinase activity	MAP kinase-activated protein kinase 5	Homo sapiens (human)
calmodulin binding	MAP kinase-activated protein kinase 5	Homo sapiens (human)
RNA binding	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
translation release factor activity	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
GTPase activity	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
protein binding	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
GTP binding	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
protein kinase activity	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
protein binding	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
ATP binding	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
kinase activity	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
ADP binding	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
protein binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
ATP binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
1-phosphatidylinositol-4-phosphate 5-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
identical protein binding	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
1-phosphatidylinositol-5-phosphate 4-kinase activity	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
chromatin binding	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
MAP kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase 15	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase 15	Homo sapiens (human)
kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
SH3 domain binding	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase 15	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein kinase binding	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein kinase activator activity	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
molecular function activator activity	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
DNA binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
chromatin binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
transcription coregulator activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
RNA binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
RNA helicase activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
double-stranded RNA binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
nuclease activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
exonuclease activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
protein binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
ATP binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
poly(A) binding	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
ATP hydrolysis activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
DNA/RNA helicase activity	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
inositol-1,3,4,5,6-pentakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol heptakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 5-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
protein binding	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
ATP binding	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 1-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol hexakisphosphate 3-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol 5-diphosphate pentakisphosphate 5-kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
inositol diphosphate tetrakisphosphate kinase activity	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Aurora kinase B	Homo sapiens (human)
protein serine/threonine kinase activity	Aurora kinase B	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Aurora kinase B	Homo sapiens (human)
protein binding	Aurora kinase B	Homo sapiens (human)
ATP binding	Aurora kinase B	Homo sapiens (human)
kinase binding	Aurora kinase B	Homo sapiens (human)
protein serine kinase activity	Aurora kinase B	Homo sapiens (human)
protein serine/threonine kinase activity	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
protein binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
ATP binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cytoskeletal anchor activity	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
gamma-tubulin binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
ubiquitin binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
tau protein binding	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
tau-protein kinase activity	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
protein serine kinase activity	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
protein tyrosine kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
14-3-3 protein binding	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
calmodulin-dependent protein kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein tyrosine kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
calcium ion binding	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
calmodulin binding	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
ATP binding	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein serine kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
p53 binding	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
protein serine/threonine kinase activity	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
protein binding	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
ATP binding	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
hydrolase activity	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
protein serine kinase activity	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
protein serine/threonine kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
protein binding	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
ATP binding	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
metal ion binding	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
protein serine kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
protein kinase activity	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
magnesium ion binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein phosphatase binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein domain specific binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
identical protein binding	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein homodimerization activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
metal ion binding	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
eukaryotic translation initiation factor 2alpha kinase activity	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protein binding	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
ATP binding	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
heme binding	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protein homodimerization activity	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
protein serine kinase activity	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
RNA binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
GTPase activity	Nucleolar GTP-binding protein 1	Homo sapiens (human)
protein binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
GTP binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
preribosome binding	Nucleolar GTP-binding protein 1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein kinase C binding	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase D2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase D2	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase D2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase D2	Homo sapiens (human)
magnesium ion binding	NUAK family SNF1-like kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	NUAK family SNF1-like kinase 2	Homo sapiens (human)
protein binding	NUAK family SNF1-like kinase 2	Homo sapiens (human)
ATP binding	NUAK family SNF1-like kinase 2	Homo sapiens (human)
protein serine kinase activity	NUAK family SNF1-like kinase 2	Homo sapiens (human)
RNA binding	RNA cytidine acetyltransferase	Homo sapiens (human)
protein binding	RNA cytidine acetyltransferase	Homo sapiens (human)
ATP binding	RNA cytidine acetyltransferase	Homo sapiens (human)
N-acetyltransferase activity	RNA cytidine acetyltransferase	Homo sapiens (human)
tRNA N-acetyltransferase activity	RNA cytidine acetyltransferase	Homo sapiens (human)
DNA polymerase binding	RNA cytidine acetyltransferase	Homo sapiens (human)
mRNA N-acetyltransferase activity	RNA cytidine acetyltransferase	Homo sapiens (human)
tRNA binding	RNA cytidine acetyltransferase	Homo sapiens (human)
rRNA cytidine N-acetyltransferase activity	RNA cytidine acetyltransferase	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
protein serine/threonine kinase activity	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein binding	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
identical protein binding	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein homodimerization activity	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cadherin binding	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein kinase inhibitor activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
transferase activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
magnesium ion binding	dCTP pyrophosphatase 1	Homo sapiens (human)
protein binding	dCTP pyrophosphatase 1	Homo sapiens (human)
pyrimidine deoxyribonucleotide binding	dCTP pyrophosphatase 1	Homo sapiens (human)
identical protein binding	dCTP pyrophosphatase 1	Homo sapiens (human)
nucleoside triphosphate diphosphatase activity	dCTP pyrophosphatase 1	Homo sapiens (human)
dCTP diphosphatase activity	dCTP pyrophosphatase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein binding	Dual specificity protein kinase CLK4	Homo sapiens (human)
ATP binding	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein serine kinase activity	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity protein kinase CLK4	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform gamma-1	Homo sapiens (human)
protein binding	Casein kinase I isoform gamma-1	Homo sapiens (human)
ATP binding	Casein kinase I isoform gamma-1	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform gamma-1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
magnesium ion binding	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
RNA binding	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
phenylalanine-tRNA ligase activity	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
protein binding	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
ATP binding	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
tRNA binding	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
aminoacyl-tRNA editing activity	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
isoleucine-tRNA ligase activity	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
ATP binding	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
protein binding	BMP-2-inducible protein kinase	Homo sapiens (human)
ATP binding	BMP-2-inducible protein kinase	Homo sapiens (human)
protein serine kinase activity	BMP-2-inducible protein kinase	Homo sapiens (human)
phosphatase regulator activity	BMP-2-inducible protein kinase	Homo sapiens (human)
AP-2 adaptor complex binding	BMP-2-inducible protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	BMP-2-inducible protein kinase	Homo sapiens (human)
protein binding	Obg-like ATPase 1	Homo sapiens (human)
ATP binding	Obg-like ATPase 1	Homo sapiens (human)
GTP binding	Obg-like ATPase 1	Homo sapiens (human)
ATP hydrolysis activity	Obg-like ATPase 1	Homo sapiens (human)
ribosomal large subunit binding	Obg-like ATPase 1	Homo sapiens (human)
cadherin binding	Obg-like ATPase 1	Homo sapiens (human)
metal ion binding	Obg-like ATPase 1	Homo sapiens (human)
protein binding	Midasin	Homo sapiens (human)
ATP binding	Midasin	Homo sapiens (human)
ATP hydrolysis activity	Midasin	Homo sapiens (human)
RNA binding	SAFB-like transcription modulator	Homo sapiens (human)
protein binding	SAFB-like transcription modulator	Homo sapiens (human)
sequence-specific DNA binding	SAFB-like transcription modulator	Homo sapiens (human)
magnesium ion binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
protein serine/threonine kinase activity	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
interleukin-1 receptor binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
protein binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
ATP binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
kinase activity	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
protein kinase binding	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
protein serine kinase activity	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
magnesium ion binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
RNA binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
JUN kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein kinase activator activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
ribosome binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
small ribosomal subunit rRNA binding	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 12	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 12	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
protein kinase binding	Cyclin-dependent kinase 12	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 12	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 12	Homo sapiens (human)
protein binding	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
ATP binding	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
endopeptidase activator activity	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 26	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 26	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein homodimerization activity	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 26	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 26	Homo sapiens (human)
magnesium ion binding	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinate-CoA ligase (ADP-forming) activity	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
protein binding	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
ATP binding	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase NLK	Homo sapiens (human)
MAP kinase activity	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
ubiquitin protein ligase binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
SH2 domain binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase NLK	Homo sapiens (human)
DNA-binding transcription factor binding	Serine/threonine-protein kinase NLK	Homo sapiens (human)
AMP-activated protein kinase activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cAMP-dependent protein kinase inhibitor activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
ATP binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cAMP-dependent protein kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
phosphorylase kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein kinase regulator activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein kinase binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
protein kinase activator activity	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
ADP binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
AMP binding	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
nucleic acid binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein phosphatase binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
phosphoprotein binding	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
protein binding	Septin-9	Homo sapiens (human)
GTP binding	Septin-9	Homo sapiens (human)
cadherin binding	Septin-9	Homo sapiens (human)
GTPase activity	Septin-9	Homo sapiens (human)
molecular adaptor activity	Septin-9	Homo sapiens (human)
magnesium ion binding	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
protein kinase activity	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
protein binding	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
ATP binding	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
protein serine kinase activity	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
ribosomal protein S6 kinase activity	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
protein kinase activity	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein binding	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
ATP binding	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein serine kinase activity	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
MAP kinase kinase kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
mitogen-activated protein kinase kinase binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
neuropilin binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein serine/threonine kinase activator activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
tau protein binding	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
long-chain fatty acid-CoA ligase activity	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
protein binding	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
ATP binding	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
arachidonate-CoA ligase activity	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
oleoyl-CoA ligase activity	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
protein tyrosine kinase activity	ALK tyrosine kinase receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	ALK tyrosine kinase receptor	Homo sapiens (human)
protein binding	ALK tyrosine kinase receptor	Homo sapiens (human)
ATP binding	ALK tyrosine kinase receptor	Homo sapiens (human)
heparin binding	ALK tyrosine kinase receptor	Homo sapiens (human)
receptor signaling protein tyrosine kinase activator activity	ALK tyrosine kinase receptor	Homo sapiens (human)
identical protein binding	ALK tyrosine kinase receptor	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase ICK	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase ICK	Homo sapiens (human)
protein kinase activity	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
protein serine/threonine kinase activity	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
protein binding	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
ATP binding	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
protein serine kinase activity	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
tau-protein kinase activity	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
protein kinase binding	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
metal ion binding	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
transcription coregulator activity	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
transcription coactivator activity	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
RNA binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
protein binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
ATP binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear receptor coactivator activity	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear vitamin D receptor binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear thyroid hormone receptor binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
phosphoprotein binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
DNA binding	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
transcription coactivator activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein tyrosine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
ATP binding	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein serine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein serine/threonine kinase activity	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
protein kinase activity	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
protein serine/threonine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
MAP kinase kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
transcription coactivator activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein kinase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein binding	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
ATP binding	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
identical protein binding	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein-containing complex binding	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein serine kinase activity	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
magnesium ion binding	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
small GTPase binding	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
protein-containing complex binding	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
magnesium ion binding	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein serine/threonine kinase activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein binding	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
ATP binding	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein kinase binding	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein homodimerization activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein heterodimerization activity	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
protein kinase activity	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase 24	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase 24	Homo sapiens (human)
cadherin binding	Serine/threonine-protein kinase 24	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase 24	Homo sapiens (human)
protein kinase activity	Casein kinase I isoform gamma-3	Homo sapiens (human)
protein serine/threonine kinase activity	Casein kinase I isoform gamma-3	Homo sapiens (human)
ATP binding	Casein kinase I isoform gamma-3	Homo sapiens (human)
protein serine kinase activity	Casein kinase I isoform gamma-3	Homo sapiens (human)
MAP kinase kinase kinase activity	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
protein binding	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
ATP binding	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
metal ion binding	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
protein serine kinase activity	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (410)

Process	via Protein(s)	Taxonomy
plasma membrane	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
dendrite	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
neuronal cell body	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
receptor complex	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
HFE-transferrin receptor complex	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-1B	Homo sapiens (human)
plasma membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
extracellular region	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
mitochondrial outer membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
endoplasmic reticulum	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
plasma membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
smooth endoplasmic reticulum membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
specific granule membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
neuron projection	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
neuronal cell body	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
cell body	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
synapse	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
endoplasmic reticulum	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
endomembrane system	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
membrane	Membrane-associated progesterone receptor component 1	Homo sapiens (human)
nucleus	Cell division cycle 7-related protein kinase	Homo sapiens (human)
nucleoplasm	Cell division cycle 7-related protein kinase	Homo sapiens (human)
cytoplasm	Cell division cycle 7-related protein kinase	Homo sapiens (human)
intercellular bridge	Cell division cycle 7-related protein kinase	Homo sapiens (human)
mitotic spindle	Cell division cycle 7-related protein kinase	Homo sapiens (human)
nucleus	Cell division cycle 7-related protein kinase	Homo sapiens (human)
cytoplasm	Cell division cycle 7-related protein kinase	Homo sapiens (human)
XY body	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
centriole	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
cleavage furrow	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
deuterosome	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
procentriole	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
procentriole replication complex	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PLK4	Homo sapiens (human)
eukaryotic translation initiation factor 3 complex	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytosolic small ribosomal subunit	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
extracellular region	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
nucleoplasm	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
centrosome	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytosol	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
plasma membrane	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cytoplasmic stress granule	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
lamellipodium	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
cell leading edge	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
secretory granule lumen	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
extracellular exosome	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
ficolin-1-rich granule lumen	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
NLRP3 inflammasome complex	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
P granule	ATP-dependent RNA helicase DDX3X	Homo sapiens (human)
extracellular region	Pyridoxal kinase	Homo sapiens (human)
nucleus	Pyridoxal kinase	Homo sapiens (human)
nucleoplasm	Pyridoxal kinase	Homo sapiens (human)
cytosol	Pyridoxal kinase	Homo sapiens (human)
secretory granule lumen	Pyridoxal kinase	Homo sapiens (human)
specific granule lumen	Pyridoxal kinase	Homo sapiens (human)
extracellular exosome	Pyridoxal kinase	Homo sapiens (human)
cytosol	Pyridoxal kinase	Homo sapiens (human)
cytosol	Citron Rho-interacting kinase	Homo sapiens (human)
membrane	Citron Rho-interacting kinase	Homo sapiens (human)
chromosome, telomeric region	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
condensed nuclear chromosome	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
extracellular space	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
replication fork	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
intracellular membrane-bounded organelle	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
chromatin	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Chk1	Homo sapiens (human)
spindle microtubule	Aurora kinase A	Homo sapiens (human)
nucleus	Aurora kinase A	Homo sapiens (human)
nucleoplasm	Aurora kinase A	Homo sapiens (human)
centrosome	Aurora kinase A	Homo sapiens (human)
centriole	Aurora kinase A	Homo sapiens (human)
spindle	Aurora kinase A	Homo sapiens (human)
cytosol	Aurora kinase A	Homo sapiens (human)
postsynaptic density	Aurora kinase A	Homo sapiens (human)
microtubule cytoskeleton	Aurora kinase A	Homo sapiens (human)
basolateral plasma membrane	Aurora kinase A	Homo sapiens (human)
midbody	Aurora kinase A	Homo sapiens (human)
spindle pole centrosome	Aurora kinase A	Homo sapiens (human)
ciliary basal body	Aurora kinase A	Homo sapiens (human)
germinal vesicle	Aurora kinase A	Homo sapiens (human)
axon hillock	Aurora kinase A	Homo sapiens (human)
pronucleus	Aurora kinase A	Homo sapiens (human)
perinuclear region of cytoplasm	Aurora kinase A	Homo sapiens (human)
mitotic spindle	Aurora kinase A	Homo sapiens (human)
meiotic spindle	Aurora kinase A	Homo sapiens (human)
mitotic spindle pole	Aurora kinase A	Homo sapiens (human)
glutamatergic synapse	Aurora kinase A	Homo sapiens (human)
spindle pole centrosome	Aurora kinase A	Homo sapiens (human)
chromosome passenger complex	Aurora kinase A	Homo sapiens (human)
spindle midzone	Aurora kinase A	Homo sapiens (human)
kinetochore	Aurora kinase A	Homo sapiens (human)
Golgi apparatus	Cyclin-G-associated kinase	Homo sapiens (human)
cytosol	Cyclin-G-associated kinase	Homo sapiens (human)
focal adhesion	Cyclin-G-associated kinase	Homo sapiens (human)
membrane	Cyclin-G-associated kinase	Homo sapiens (human)
clathrin-coated vesicle	Cyclin-G-associated kinase	Homo sapiens (human)
vesicle	Cyclin-G-associated kinase	Homo sapiens (human)
intracellular membrane-bounded organelle	Cyclin-G-associated kinase	Homo sapiens (human)
perinuclear region of cytoplasm	Cyclin-G-associated kinase	Homo sapiens (human)
presynapse	Cyclin-G-associated kinase	Homo sapiens (human)
vesicle	Cyclin-G-associated kinase	Homo sapiens (human)
cytoplasm	Cyclin-G-associated kinase	Homo sapiens (human)
intracellular membrane-bounded organelle	Cyclin-G-associated kinase	Homo sapiens (human)
extracellular region	Ephrin type-B receptor 6	Homo sapiens (human)
cytosol	Ephrin type-B receptor 6	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 6	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 6	Homo sapiens (human)
dendrite	Ephrin type-B receptor 6	Homo sapiens (human)
peroxisome	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
peroxisomal matrix	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
cytosol	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
membrane	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
peroxisome	Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)
plasma membrane	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cytoplasm	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
endoplasmic reticulum	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cytosol	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
cytoskeleton	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
vesicle	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
protein-containing complex	Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)
kinetochore	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
nucleoplasm	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
cytosol	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
membrane	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
intracellular membrane-bounded organelle	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
outer kinetochore	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
kinetochore	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
nucleus	Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)
nucleoplasm	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrion	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial outer membrane	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial inner membrane	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial intermembrane space	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cytosol	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
membrane	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial crista	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
dendrite	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
axon cytoplasm	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial intermembrane space	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
cytoplasm	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
microtubule	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
mitochondrial membrane	Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)
extrinsic component of plasma membrane	Tyrosine-protein kinase JAK2	Homo sapiens (human)
extrinsic component of cytoplasmic side of plasma membrane	Tyrosine-protein kinase JAK2	Homo sapiens (human)
nucleus	Tyrosine-protein kinase JAK2	Homo sapiens (human)
nucleoplasm	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytoskeleton	Tyrosine-protein kinase JAK2	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase JAK2	Homo sapiens (human)
caveola	Tyrosine-protein kinase JAK2	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase JAK2	Homo sapiens (human)
granulocyte macrophage colony-stimulating factor receptor complex	Tyrosine-protein kinase JAK2	Homo sapiens (human)
endosome lumen	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-12 receptor complex	Tyrosine-protein kinase JAK2	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase JAK2	Homo sapiens (human)
interleukin-23 receptor complex	Tyrosine-protein kinase JAK2	Homo sapiens (human)
postsynapse	Tyrosine-protein kinase JAK2	Homo sapiens (human)
glutamatergic synapse	Tyrosine-protein kinase JAK2	Homo sapiens (human)
euchromatin	Tyrosine-protein kinase JAK2	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK2	Homo sapiens (human)
nucleus	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
cytoplasm	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
cytosol	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
synapse	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
cytoplasm	Eukaryotic translation initiation factor 5B	Homo sapiens (human)
nucleus	Rho-associated protein kinase 2	Homo sapiens (human)
centrosome	Rho-associated protein kinase 2	Homo sapiens (human)
cytosol	Rho-associated protein kinase 2	Homo sapiens (human)
plasma membrane	Rho-associated protein kinase 2	Homo sapiens (human)
cytoplasmic ribonucleoprotein granule	Rho-associated protein kinase 2	Homo sapiens (human)
centrosome	Rho-associated protein kinase 2	Homo sapiens (human)
cytoskeleton	Rho-associated protein kinase 2	Homo sapiens (human)
cytoplasm	Rho-associated protein kinase 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
phagophore assembly site	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagosome membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
mitochondrial outer membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagosome	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
endoplasmic reticulum membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
axon	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
phagophore assembly site membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
recycling endosome	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
omegasome membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
Atg1/ULK1 kinase complex	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
phagophore assembly site	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
autophagosome	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
phagophore assembly site membrane	Serine/threonine-protein kinase ULK1	Homo sapiens (human)
nuclear inner membrane	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
endoplasmic reticulum	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
endoplasmic reticulum membrane	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
Ire1 complex	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
AIP1-IRE1 complex	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
IRE1-TRAF2-ASK1 complex	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
IRE1-RACK1-PP2A complex	Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)
nucleus	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)
nucleus	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
nucleoplasm	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
membrane	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
U4/U6 x U5 tri-snRNP complex	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
spliceosomal complex	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
U5 snRNP	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
U2-type precatalytic spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
U2-type catalytic step 1 spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
catalytic step 2 spliceosome	U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)
nucleus	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
synapse	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase 16	Homo sapiens (human)
Golgi-associated vesicle	Serine/threonine-protein kinase 16	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 16	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase 16	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase 16	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 16	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 16	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 10	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase 10	Homo sapiens (human)
specific granule membrane	Serine/threonine-protein kinase 10	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase 10	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 10	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase D3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D3	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase D3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D3	Homo sapiens (human)
nuclear chromosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
condensed chromosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
condensed nuclear chromosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
condensin complex	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
nucleus	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
nucleoplasm	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
nucleolus	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
cytoplasm	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
cytosol	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
extracellular exosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
condensed chromosome	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
chromatin	Structural maintenance of chromosomes protein 2	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
focal adhesion	Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
midbody	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase LATS1	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
adherens junction	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
focal adhesion	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 4	Homo sapiens (human)
ruffle	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nucleus	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nucleoplasm	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nucleolus	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase ABL1	Homo sapiens (human)
mitochondrion	Tyrosine-protein kinase ABL1	Homo sapiens (human)
cytosol	Tyrosine-protein kinase ABL1	Homo sapiens (human)
actin cytoskeleton	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nuclear body	Tyrosine-protein kinase ABL1	Homo sapiens (human)
dendrite	Tyrosine-protein kinase ABL1	Homo sapiens (human)
growth cone	Tyrosine-protein kinase ABL1	Homo sapiens (human)
nuclear membrane	Tyrosine-protein kinase ABL1	Homo sapiens (human)
neuronal cell body	Tyrosine-protein kinase ABL1	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase ABL1	Homo sapiens (human)
postsynapse	Tyrosine-protein kinase ABL1	Homo sapiens (human)
protein-containing complex	Tyrosine-protein kinase ABL1	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase ABL1	Homo sapiens (human)
endosome	Epidermal growth factor receptor	Homo sapiens (human)
plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
ruffle membrane	Epidermal growth factor receptor	Homo sapiens (human)
Golgi membrane	Epidermal growth factor receptor	Homo sapiens (human)
extracellular space	Epidermal growth factor receptor	Homo sapiens (human)
nucleus	Epidermal growth factor receptor	Homo sapiens (human)
cytoplasm	Epidermal growth factor receptor	Homo sapiens (human)
endosome	Epidermal growth factor receptor	Homo sapiens (human)
endoplasmic reticulum membrane	Epidermal growth factor receptor	Homo sapiens (human)
plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
focal adhesion	Epidermal growth factor receptor	Homo sapiens (human)
cell surface	Epidermal growth factor receptor	Homo sapiens (human)
endosome membrane	Epidermal growth factor receptor	Homo sapiens (human)
membrane	Epidermal growth factor receptor	Homo sapiens (human)
basolateral plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
apical plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
cell junction	Epidermal growth factor receptor	Homo sapiens (human)
clathrin-coated endocytic vesicle membrane	Epidermal growth factor receptor	Homo sapiens (human)
early endosome membrane	Epidermal growth factor receptor	Homo sapiens (human)
nuclear membrane	Epidermal growth factor receptor	Homo sapiens (human)
membrane raft	Epidermal growth factor receptor	Homo sapiens (human)
perinuclear region of cytoplasm	Epidermal growth factor receptor	Homo sapiens (human)
multivesicular body, internal vesicle lumen	Epidermal growth factor receptor	Homo sapiens (human)
intracellular vesicle	Epidermal growth factor receptor	Homo sapiens (human)
protein-containing complex	Epidermal growth factor receptor	Homo sapiens (human)
receptor complex	Epidermal growth factor receptor	Homo sapiens (human)
Shc-EGFR complex	Epidermal growth factor receptor	Homo sapiens (human)
basal plasma membrane	Epidermal growth factor receptor	Homo sapiens (human)
extracellular space	Interferon beta	Homo sapiens (human)
extracellular region	Interferon beta	Homo sapiens (human)
Golgi membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
endoplasmic reticulum	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
Golgi apparatus	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
plasma membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
cell surface	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
ER to Golgi transport vesicle membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
secretory granule membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
phagocytic vesicle membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
early endosome membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
recycling endosome membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
extracellular exosome	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
lumenal side of endoplasmic reticulum membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
MHC class I protein complex	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
extracellular space	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
external side of plasma membrane	HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)
early endosome	High affinity nerve growth factor receptor	Homo sapiens (human)
late endosome	High affinity nerve growth factor receptor	Homo sapiens (human)
plasma membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
cell surface	High affinity nerve growth factor receptor	Homo sapiens (human)
endosome membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
dendrite	High affinity nerve growth factor receptor	Homo sapiens (human)
early endosome membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
late endosome membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
neuronal cell body	High affinity nerve growth factor receptor	Homo sapiens (human)
recycling endosome membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
protein-containing complex	High affinity nerve growth factor receptor	Homo sapiens (human)
receptor complex	High affinity nerve growth factor receptor	Homo sapiens (human)
axon	High affinity nerve growth factor receptor	Homo sapiens (human)
plasma membrane	High affinity nerve growth factor receptor	Homo sapiens (human)
nucleoplasm	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
cytoplasm	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
centrosome	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
cytosol	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
plasma membrane	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
membrane	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
dendrite	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
midbody	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
cell body	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
synapse	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
extracellular exosome	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
neuronal dense core vesicle	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
extracellular vesicle	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
heterotrimeric G-protein complex	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
cytoplasm	Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)
nucleus	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrion	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial inner membrane	ADP/ATP translocase 2	Homo sapiens (human)
plasma membrane	ADP/ATP translocase 2	Homo sapiens (human)
membrane	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial nucleoid	ADP/ATP translocase 2	Homo sapiens (human)
mitochondrial permeability transition pore complex	ADP/ATP translocase 2	Homo sapiens (human)
MMXD complex	ADP/ATP translocase 2	Homo sapiens (human)
nucleus	Protein kinase C beta type	Homo sapiens (human)
nucleoplasm	Protein kinase C beta type	Homo sapiens (human)
cytoplasm	Protein kinase C beta type	Homo sapiens (human)
centrosome	Protein kinase C beta type	Homo sapiens (human)
cytosol	Protein kinase C beta type	Homo sapiens (human)
plasma membrane	Protein kinase C beta type	Homo sapiens (human)
brush border membrane	Protein kinase C beta type	Homo sapiens (human)
calyx of Held	Protein kinase C beta type	Homo sapiens (human)
extracellular exosome	Protein kinase C beta type	Homo sapiens (human)
presynaptic cytosol	Protein kinase C beta type	Homo sapiens (human)
spectrin	Protein kinase C beta type	Homo sapiens (human)
nuclear envelope	Insulin receptor	Homo sapiens (human)
nuclear lumen	Insulin receptor	Homo sapiens (human)
lysosome	Insulin receptor	Homo sapiens (human)
late endosome	Insulin receptor	Homo sapiens (human)
plasma membrane	Insulin receptor	Homo sapiens (human)
caveola	Insulin receptor	Homo sapiens (human)
external side of plasma membrane	Insulin receptor	Homo sapiens (human)
endosome membrane	Insulin receptor	Homo sapiens (human)
membrane	Insulin receptor	Homo sapiens (human)
dendrite membrane	Insulin receptor	Homo sapiens (human)
neuronal cell body membrane	Insulin receptor	Homo sapiens (human)
extracellular exosome	Insulin receptor	Homo sapiens (human)
insulin receptor complex	Insulin receptor	Homo sapiens (human)
receptor complex	Insulin receptor	Homo sapiens (human)
plasma membrane	Insulin receptor	Homo sapiens (human)
axon	Insulin receptor	Homo sapiens (human)
pericentriolar material	Tyrosine-protein kinase Lck	Homo sapiens (human)
immunological synapse	Tyrosine-protein kinase Lck	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Lck	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lck	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Lck	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Lck	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lck	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendrite	Tyrosine-protein kinase Fyn	Homo sapiens (human)
nucleus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
mitochondrion	Tyrosine-protein kinase Fyn	Homo sapiens (human)
endosome	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Fyn	Homo sapiens (human)
actin filament	Tyrosine-protein kinase Fyn	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
postsynaptic density	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendrite	Tyrosine-protein kinase Fyn	Homo sapiens (human)
perikaryon	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cell body	Tyrosine-protein kinase Fyn	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Fyn	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase Fyn	Homo sapiens (human)
perinuclear endoplasmic reticulum	Tyrosine-protein kinase Fyn	Homo sapiens (human)
glial cell projection	Tyrosine-protein kinase Fyn	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Tyrosine-protein kinase Fyn	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
mitochondrial matrix	Cyclin-dependent kinase 1	Homo sapiens (human)
chromosome, telomeric region	Cyclin-dependent kinase 1	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 1	Homo sapiens (human)
mitochondrion	Cyclin-dependent kinase 1	Homo sapiens (human)
endoplasmic reticulum membrane	Cyclin-dependent kinase 1	Homo sapiens (human)
centrosome	Cyclin-dependent kinase 1	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 1	Homo sapiens (human)
spindle microtubule	Cyclin-dependent kinase 1	Homo sapiens (human)
membrane	Cyclin-dependent kinase 1	Homo sapiens (human)
midbody	Cyclin-dependent kinase 1	Homo sapiens (human)
extracellular exosome	Cyclin-dependent kinase 1	Homo sapiens (human)
mitotic spindle	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin A1-CDK1 complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin A2-CDK1 complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin B1-CDK1 complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 1	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
extracellular region	Glycogen phosphorylase, liver form	Homo sapiens (human)
cytosol	Glycogen phosphorylase, liver form	Homo sapiens (human)
secretory granule lumen	Glycogen phosphorylase, liver form	Homo sapiens (human)
extracellular exosome	Glycogen phosphorylase, liver form	Homo sapiens (human)
ficolin-1-rich granule lumen	Glycogen phosphorylase, liver form	Homo sapiens (human)
cytoplasm	Glycogen phosphorylase, liver form	Homo sapiens (human)
cytoplasmic vesicle	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
microtubule cytoskeleton	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)
extracellular region	Adenine phosphoribosyltransferase	Homo sapiens (human)
nucleoplasm	Adenine phosphoribosyltransferase	Homo sapiens (human)
cytoplasm	Adenine phosphoribosyltransferase	Homo sapiens (human)
cytosol	Adenine phosphoribosyltransferase	Homo sapiens (human)
secretory granule lumen	Adenine phosphoribosyltransferase	Homo sapiens (human)
extracellular exosome	Adenine phosphoribosyltransferase	Homo sapiens (human)
cytoplasm	Adenine phosphoribosyltransferase	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase Yes	Homo sapiens (human)
centrosome	Tyrosine-protein kinase Yes	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Yes	Homo sapiens (human)
actin filament	Tyrosine-protein kinase Yes	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Yes	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase Yes	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Yes	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Yes	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
nucleus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase Lyn	Homo sapiens (human)
lysosomal membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Lyn	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
adherens junction	Tyrosine-protein kinase Lyn	Homo sapiens (human)
mitochondrial crista	Tyrosine-protein kinase Lyn	Homo sapiens (human)
endocytic vesicle membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
intracellular membrane-bounded organelle	Tyrosine-protein kinase Lyn	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Lyn	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase Lyn	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Lyn	Homo sapiens (human)
glutamatergic synapse	Tyrosine-protein kinase Lyn	Homo sapiens (human)
postsynaptic specialization, intracellular component	Tyrosine-protein kinase Lyn	Homo sapiens (human)
integrin alpha2-beta1 complex	Tyrosine-protein kinase Lyn	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
early endosome	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
endosome membrane	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
dendrite	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
neuronal cell body	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
receptor complex	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
plasma membrane protein complex	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
axon	Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)
plasma membrane	Insulin-like growth factor 1 receptor	Homo sapiens (human)
caveola	Insulin-like growth factor 1 receptor	Homo sapiens (human)
membrane	Insulin-like growth factor 1 receptor	Homo sapiens (human)
T-tubule	Insulin-like growth factor 1 receptor	Homo sapiens (human)
neuronal cell body	Insulin-like growth factor 1 receptor	Homo sapiens (human)
intracellular membrane-bounded organelle	Insulin-like growth factor 1 receptor	Homo sapiens (human)
alphav-beta3 integrin-IGF-1-IGF1R complex	Insulin-like growth factor 1 receptor	Homo sapiens (human)
receptor complex	Insulin-like growth factor 1 receptor	Homo sapiens (human)
protein kinase complex	Insulin-like growth factor 1 receptor	Homo sapiens (human)
axon	Insulin-like growth factor 1 receptor	Homo sapiens (human)
plasma membrane	Insulin-like growth factor 1 receptor	Homo sapiens (human)
insulin receptor complex	Insulin-like growth factor 1 receptor	Homo sapiens (human)
signal recognition particle receptor complex	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
endoplasmic reticulum membrane	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
membrane	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
extracellular exosome	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
endoplasmic reticulum membrane	Signal recognition particle receptor subunit alpha	Homo sapiens (human)
nucleus	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
mitochondrion	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
mitochondrial inner membrane	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
mitochondrial respiratory chain complex III	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
membrane	Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)
extracellular region	Hepatocyte growth factor receptor	Homo sapiens (human)
plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
basal plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
cell surface	Hepatocyte growth factor receptor	Homo sapiens (human)
membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
postsynapse	Hepatocyte growth factor receptor	Homo sapiens (human)
basal plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
receptor complex	Hepatocyte growth factor receptor	Homo sapiens (human)
actin filament	Tyrosine-protein kinase HCK	Homo sapiens (human)
nucleus	Tyrosine-protein kinase HCK	Homo sapiens (human)
lysosome	Tyrosine-protein kinase HCK	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase HCK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase HCK	Homo sapiens (human)
caveola	Tyrosine-protein kinase HCK	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase HCK	Homo sapiens (human)
transport vesicle	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell projection	Tyrosine-protein kinase HCK	Homo sapiens (human)
intracellular membrane-bounded organelle	Tyrosine-protein kinase HCK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase HCK	Homo sapiens (human)
nucleus	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cytoplasm	Platelet-derived growth factor receptor beta	Homo sapiens (human)
Golgi apparatus	Platelet-derived growth factor receptor beta	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
focal adhesion	Platelet-derived growth factor receptor beta	Homo sapiens (human)
membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
apical plasma membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cytoplasmic vesicle	Platelet-derived growth factor receptor beta	Homo sapiens (human)
lysosomal lumen	Platelet-derived growth factor receptor beta	Homo sapiens (human)
intracellular membrane-bounded organelle	Platelet-derived growth factor receptor beta	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
receptor complex	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cellular_component	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase A-Raf	Homo sapiens (human)
fibrillar center	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
acrosomal vesicle	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
extracellular space	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
plasma membrane	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cell-cell junction	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
external side of plasma membrane	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
cytoplasmic side of plasma membrane	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
plasma membrane	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
receptor complex	Mast/stem cell growth factor receptor Kit	Homo sapiens (human)
extracellular region	Glycogen phosphorylase, brain form	Homo sapiens (human)
cytoplasm	Glycogen phosphorylase, brain form	Homo sapiens (human)
membrane	Glycogen phosphorylase, brain form	Homo sapiens (human)
azurophil granule lumen	Glycogen phosphorylase, brain form	Homo sapiens (human)
extracellular exosome	Glycogen phosphorylase, brain form	Homo sapiens (human)
cytoplasm	Glycogen phosphorylase, brain form	Homo sapiens (human)
cytosol	Breakpoint cluster region protein	Homo sapiens (human)
plasma membrane	Breakpoint cluster region protein	Homo sapiens (human)
postsynaptic density	Breakpoint cluster region protein	Homo sapiens (human)
membrane	Breakpoint cluster region protein	Homo sapiens (human)
axon	Breakpoint cluster region protein	Homo sapiens (human)
dendritic spine	Breakpoint cluster region protein	Homo sapiens (human)
extracellular exosome	Breakpoint cluster region protein	Homo sapiens (human)
protein-containing complex	Breakpoint cluster region protein	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Breakpoint cluster region protein	Homo sapiens (human)
glutamatergic synapse	Breakpoint cluster region protein	Homo sapiens (human)
membrane	Breakpoint cluster region protein	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase pim-1	Homo sapiens (human)
extracellular region	Fibroblast growth factor receptor 1	Homo sapiens (human)
nucleus	Fibroblast growth factor receptor 1	Homo sapiens (human)
cytosol	Fibroblast growth factor receptor 1	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 1	Homo sapiens (human)
membrane	Fibroblast growth factor receptor 1	Homo sapiens (human)
cytoplasmic vesicle	Fibroblast growth factor receptor 1	Homo sapiens (human)
receptor complex	Fibroblast growth factor receptor 1	Homo sapiens (human)
plasma membrane	Fibroblast growth factor receptor 1	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 4	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 4	Homo sapiens (human)
nucleolus	Cyclin-dependent kinase 4	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 4	Homo sapiens (human)
bicellular tight junction	Cyclin-dependent kinase 4	Homo sapiens (human)
nuclear membrane	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin D1-CDK4 complex	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin D2-CDK4 complex	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin D3-CDK4 complex	Cyclin-dependent kinase 4	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 4	Homo sapiens (human)
chromatin	Cyclin-dependent kinase 4	Homo sapiens (human)
transcription regulator complex	Cyclin-dependent kinase 4	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 4	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 4	Homo sapiens (human)
nucleus	ADP/ATP translocase 3	Homo sapiens (human)
mitochondrion	ADP/ATP translocase 3	Homo sapiens (human)
mitochondrial inner membrane	ADP/ATP translocase 3	Homo sapiens (human)
membrane	ADP/ATP translocase 3	Homo sapiens (human)
TIM23 mitochondrial import inner membrane translocase complex	ADP/ATP translocase 3	Homo sapiens (human)
extracellular region	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
nucleus	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
cytoplasm	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
peroxisomal membrane	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
cytosol	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
membrane	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
secretory granule lumen	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
extracellular exosome	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
ficolin-1-rich granule lumen	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
cytoplasm	Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)
podosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
nucleoplasm	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cytoplasm	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
mitochondrion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
mitochondrial inner membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
lysosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
late endosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cytosol	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
actin filament	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
caveola	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
focal adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell junction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ruffle membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
neuronal cell body	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
dendritic growth cone	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
membrane raft	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
perinuclear region of cytoplasm	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
extracellular exosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
synaptic membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
glutamatergic synapse	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
postsynaptic specialization, intracellular component	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
dendritic filopodium	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
axoneme	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cytoplasm	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
centrosome	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
plasma membrane	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
focal adhesion	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
membrane	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
plasma membrane raft	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
extracellular exosome	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
ciliary base	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cAMP-dependent protein kinase complex	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
nucleotide-activated protein kinase complex	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
protein-containing complex	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
neuron projection	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
intracellular membrane-bounded organelle	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cell body	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
presynapse	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase B-raf	Homo sapiens (human)
cytosol	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
phosphorylase kinase complex	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)
nucleoplasm	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
cytosol	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
extracellular exosome	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
cytosol	Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)
nucleus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
nucleoplasm	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cytoplasm	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
endoplasmic reticulum membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
Golgi apparatus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
microvillus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cilium	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
external side of plasma membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell junction	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein-containing complex	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
receptor complex	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
actin cytoskeleton	Tyrosine-protein kinase Fer	Homo sapiens (human)
microtubule cytoskeleton	Tyrosine-protein kinase Fer	Homo sapiens (human)
lamellipodium	Tyrosine-protein kinase Fer	Homo sapiens (human)
cell junction	Tyrosine-protein kinase Fer	Homo sapiens (human)
nucleus	Tyrosine-protein kinase Fer	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase Fer	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Fer	Homo sapiens (human)
adherens junction	Tyrosine-protein kinase Fer	Homo sapiens (human)
cell cortex	Tyrosine-protein kinase Fer	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase Fer	Homo sapiens (human)
chromatin	Tyrosine-protein kinase Fer	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fer	Homo sapiens (human)
ciliary basal body	Protein kinase C alpha type	Homo sapiens (human)
nucleoplasm	Protein kinase C alpha type	Homo sapiens (human)
cytoplasm	Protein kinase C alpha type	Homo sapiens (human)
mitochondrion	Protein kinase C alpha type	Homo sapiens (human)
endoplasmic reticulum	Protein kinase C alpha type	Homo sapiens (human)
cytosol	Protein kinase C alpha type	Homo sapiens (human)
plasma membrane	Protein kinase C alpha type	Homo sapiens (human)
mitochondrial membrane	Protein kinase C alpha type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C alpha type	Homo sapiens (human)
extracellular exosome	Protein kinase C alpha type	Homo sapiens (human)
alphav-beta3 integrin-PKCalpha complex	Protein kinase C alpha type	Homo sapiens (human)
axoneme	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytoplasm	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
acrosomal vesicle	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
nucleus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
nucleoplasm	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytoplasm	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
mitochondrial matrix	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
centrosome	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
plasma membrane	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
nuclear speck	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
neuromuscular junction	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
sperm flagellum	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
dendritic spine	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
plasma membrane raft	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
perinuclear region of cytoplasm	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
extracellular exosome	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
ciliary base	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
glutamatergic synapse	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cAMP-dependent protein kinase complex	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
calcium channel complex	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
nucleus	cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)
extracellular space	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
endosome	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
focal adhesion	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
actin cytoskeleton	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
receptor complex	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 1	Homo sapiens (human)
nucleus	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
nucleoplasm	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
cytoplasm	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
spindle	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
cytosol	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription factor TFIIH core complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription factor TFIID complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
transcription factor TFIIH holo complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
CAK-ERCC2 complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
MMXD complex	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
nucleus	General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)
PcG protein complex	Casein kinase II subunit alpha'	Homo sapiens (human)
acrosomal vesicle	Casein kinase II subunit alpha'	Homo sapiens (human)
nucleus	Casein kinase II subunit alpha'	Homo sapiens (human)
nucleoplasm	Casein kinase II subunit alpha'	Homo sapiens (human)
cytosol	Casein kinase II subunit alpha'	Homo sapiens (human)
protein kinase CK2 complex	Casein kinase II subunit alpha'	Homo sapiens (human)
chromatin	Casein kinase II subunit alpha'	Homo sapiens (human)
cytosol	Casein kinase II subunit alpha'	Homo sapiens (human)
nucleus	Casein kinase II subunit alpha'	Homo sapiens (human)
Golgi membrane	Ras-related protein Rab-6A	Homo sapiens (human)
acrosomal membrane	Ras-related protein Rab-6A	Homo sapiens (human)
endoplasmic reticulum membrane	Ras-related protein Rab-6A	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-6A	Homo sapiens (human)
trans-Golgi network	Ras-related protein Rab-6A	Homo sapiens (human)
cytosol	Ras-related protein Rab-6A	Homo sapiens (human)
plasma membrane	Ras-related protein Rab-6A	Homo sapiens (human)
membrane	Ras-related protein Rab-6A	Homo sapiens (human)
secretory granule membrane	Ras-related protein Rab-6A	Homo sapiens (human)
cytoplasmic vesicle	Ras-related protein Rab-6A	Homo sapiens (human)
trans-Golgi network membrane	Ras-related protein Rab-6A	Homo sapiens (human)
extracellular exosome	Ras-related protein Rab-6A	Homo sapiens (human)
endosome to plasma membrane transport vesicle	Ras-related protein Rab-6A	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-6A	Homo sapiens (human)
endomembrane system	Ras-related protein Rab-6A	Homo sapiens (human)
cytoplasm	Multifunctional protein ADE2	Homo sapiens (human)
cytosol	Multifunctional protein ADE2	Homo sapiens (human)
membrane	Multifunctional protein ADE2	Homo sapiens (human)
extracellular exosome	Multifunctional protein ADE2	Homo sapiens (human)
nucleoplasm	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
ciliary base	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
nucleus	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
cAMP-dependent protein kinase complex	cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)
nucleoplasm	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
centrosome	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
plasma membrane	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
extracellular exosome	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
ciliary base	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
cAMP-dependent protein kinase complex	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
cytosol	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
nucleus	cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)
mitochondrial inner membrane	Ferrochelatase, mitochondrial	Homo sapiens (human)
mitochondrial matrix	Ferrochelatase, mitochondrial	Homo sapiens (human)
mitochondrion	Ferrochelatase, mitochondrial	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
mitochondrion	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
mitochondrial outer membrane	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cell surface	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
neuron projection	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
perinuclear region of cytoplasm	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
postsynapse	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
glutamatergic synapse	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase beta-1	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase JAK1	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase JAK1	Homo sapiens (human)
extrinsic component of cytoplasmic side of plasma membrane	Tyrosine-protein kinase JAK1	Homo sapiens (human)
nucleus	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase JAK1	Homo sapiens (human)
endosome	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytoskeleton	Tyrosine-protein kinase JAK1	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase JAK1	Homo sapiens (human)
cytosol	Tyrosine-protein kinase JAK1	Homo sapiens (human)
chromosome, telomeric region	Cyclin-dependent kinase 2	Homo sapiens (human)
condensed chromosome	Cyclin-dependent kinase 2	Homo sapiens (human)
X chromosome	Cyclin-dependent kinase 2	Homo sapiens (human)
Y chromosome	Cyclin-dependent kinase 2	Homo sapiens (human)
male germ cell nucleus	Cyclin-dependent kinase 2	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 2	Homo sapiens (human)
nuclear envelope	Cyclin-dependent kinase 2	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 2	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 2	Homo sapiens (human)
endosome	Cyclin-dependent kinase 2	Homo sapiens (human)
centrosome	Cyclin-dependent kinase 2	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 2	Homo sapiens (human)
Cajal body	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin A1-CDK2 complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin A2-CDK2 complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin E1-CDK2 complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin E2-CDK2 complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 2	Homo sapiens (human)
transcription regulator complex	Cyclin-dependent kinase 2	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 2	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 2	Homo sapiens (human)
cytoplasm	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
cytosol	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
plasma membrane	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
cilium	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
membrane	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
presynapse	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
postsynapse	Beta-adrenergic receptor kinase 1	Homo sapiens (human)
P-body	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
nucleus	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytoplasm	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytosol	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytoplasmic stress granule	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
membrane	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytoplasmic ribonucleoprotein granule	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
RISC complex	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
cytoplasmic stress granule	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
P-body	Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 3	Homo sapiens (human)
nuclear envelope	Mitogen-activated protein kinase 3	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 3	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 3	Homo sapiens (human)
early endosome	Mitogen-activated protein kinase 3	Homo sapiens (human)
late endosome	Mitogen-activated protein kinase 3	Homo sapiens (human)
endoplasmic reticulum lumen	Mitogen-activated protein kinase 3	Homo sapiens (human)
Golgi apparatus	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytoskeleton	Mitogen-activated protein kinase 3	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase 3	Homo sapiens (human)
caveola	Mitogen-activated protein kinase 3	Homo sapiens (human)
focal adhesion	Mitogen-activated protein kinase 3	Homo sapiens (human)
pseudopodium	Mitogen-activated protein kinase 3	Homo sapiens (human)
glutamatergic synapse	Mitogen-activated protein kinase 3	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 3	Homo sapiens (human)
cytoplasm	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
cytosol	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
plasma membrane	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
dendrite	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
extracellular exosome	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
plasma membrane	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
cytoplasm	MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)
nucleoplasm	Deoxycytidine kinase	Homo sapiens (human)
cytosol	Deoxycytidine kinase	Homo sapiens (human)
mitochondrion	Deoxycytidine kinase	Homo sapiens (human)
cytoplasm	Deoxycytidine kinase	Homo sapiens (human)
extracellular region	Mitogen-activated protein kinase 1	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 1	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 1	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 1	Homo sapiens (human)
early endosome	Mitogen-activated protein kinase 1	Homo sapiens (human)
late endosome	Mitogen-activated protein kinase 1	Homo sapiens (human)
endoplasmic reticulum lumen	Mitogen-activated protein kinase 1	Homo sapiens (human)
Golgi apparatus	Mitogen-activated protein kinase 1	Homo sapiens (human)
centrosome	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytoskeleton	Mitogen-activated protein kinase 1	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase 1	Homo sapiens (human)
caveola	Mitogen-activated protein kinase 1	Homo sapiens (human)
focal adhesion	Mitogen-activated protein kinase 1	Homo sapiens (human)
pseudopodium	Mitogen-activated protein kinase 1	Homo sapiens (human)
azurophil granule lumen	Mitogen-activated protein kinase 1	Homo sapiens (human)
synapse	Mitogen-activated protein kinase 1	Homo sapiens (human)
mitotic spindle	Mitogen-activated protein kinase 1	Homo sapiens (human)
ficolin-1-rich granule lumen	Mitogen-activated protein kinase 1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 1	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 1	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 2	Homo sapiens (human)
focal adhesion	Ephrin type-A receptor 2	Homo sapiens (human)
cell surface	Ephrin type-A receptor 2	Homo sapiens (human)
lamellipodium	Ephrin type-A receptor 2	Homo sapiens (human)
leading edge membrane	Ephrin type-A receptor 2	Homo sapiens (human)
lamellipodium membrane	Ephrin type-A receptor 2	Homo sapiens (human)
ruffle membrane	Ephrin type-A receptor 2	Homo sapiens (human)
tight junction	Ephrin type-A receptor 2	Homo sapiens (human)
receptor complex	Ephrin type-A receptor 2	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 2	Homo sapiens (human)
extracellular region	Ephrin type-B receptor 2	Homo sapiens (human)
nucleoplasm	Ephrin type-B receptor 2	Homo sapiens (human)
cytosol	Ephrin type-B receptor 2	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 2	Homo sapiens (human)
cell surface	Ephrin type-B receptor 2	Homo sapiens (human)
axon	Ephrin type-B receptor 2	Homo sapiens (human)
dendrite	Ephrin type-B receptor 2	Homo sapiens (human)
presynaptic membrane	Ephrin type-B receptor 2	Homo sapiens (human)
neuronal cell body	Ephrin type-B receptor 2	Homo sapiens (human)
dendritic spine	Ephrin type-B receptor 2	Homo sapiens (human)
postsynaptic membrane	Ephrin type-B receptor 2	Homo sapiens (human)
hippocampal mossy fiber to CA3 synapse	Ephrin type-B receptor 2	Homo sapiens (human)
postsynapse	Ephrin type-B receptor 2	Homo sapiens (human)
glutamatergic synapse	Ephrin type-B receptor 2	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 2	Homo sapiens (human)
dendrite	Ephrin type-B receptor 2	Homo sapiens (human)
plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytoplasmic side of plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
extrinsic component of plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
extrinsic component of cytoplasmic side of plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
nucleus	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytoplasm	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytosol	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytoskeleton	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
plasma membrane	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
interleukin-12 receptor complex	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
extracellular exosome	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
interleukin-23 receptor complex	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
cytosol	Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)
nucleoplasm	UMP-CMP kinase	Homo sapiens (human)
nucleolus	UMP-CMP kinase	Homo sapiens (human)
cytosol	UMP-CMP kinase	Homo sapiens (human)
extracellular exosome	UMP-CMP kinase	Homo sapiens (human)
cytoplasm	UMP-CMP kinase	Homo sapiens (human)
nucleus	UMP-CMP kinase	Homo sapiens (human)
nucleus	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
cytosol	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
extracellular exosome	Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)
nucleus	Wee1-like protein kinase	Homo sapiens (human)
nucleoplasm	Wee1-like protein kinase	Homo sapiens (human)
nucleolus	Wee1-like protein kinase	Homo sapiens (human)
cytoplasm	Wee1-like protein kinase	Homo sapiens (human)
endoplasmic reticulum membrane	Heme oxygenase 2	Homo sapiens (human)
plasma membrane	Heme oxygenase 2	Homo sapiens (human)
membrane	Heme oxygenase 2	Homo sapiens (human)
specific granule membrane	Heme oxygenase 2	Homo sapiens (human)
extracellular space	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cell surface	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
actin cytoskeleton	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
intracellular membrane-bounded organelle	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
receptor complex	Tyrosine-protein kinase receptor UFO	Homo sapiens (human)
cytosol	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
methionine adenosyltransferase complex	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
cytosol	S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)
nucleus	DnaJ homolog subfamily A member 1	Homo sapiens (human)
mitochondrion	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytosol	DnaJ homolog subfamily A member 1	Homo sapiens (human)
microtubule cytoskeleton	DnaJ homolog subfamily A member 1	Homo sapiens (human)
membrane	DnaJ homolog subfamily A member 1	Homo sapiens (human)
perinuclear region of cytoplasm	DnaJ homolog subfamily A member 1	Homo sapiens (human)
extracellular exosome	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytoplasmic side of endoplasmic reticulum membrane	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytoplasm	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytosol	DnaJ homolog subfamily A member 1	Homo sapiens (human)
cytoplasm	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
mitochondrial intermembrane space	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
membrane	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nucleus	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nucleoplasm	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
spindle	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cytosol	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
plasma membrane	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell-cell junction	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
cell cortex	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
microtubule cytoskeleton	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
lamellipodium	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
vesicle	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
ciliary basal body	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
postsynapse	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
glutamatergic synapse	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
protein-containing complex	RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)
nucleus	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
nucleoplasm	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
early endosome	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
cytosol	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
plasma membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
cell cortex	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
ruffle membrane	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
intracellular membrane-bounded organelle	RAC-beta serine/threonine-protein kinase	Homo sapiens (human)
mitochondrion	Kinesin-1 heavy chain	Homo sapiens (human)
cytosol	Kinesin-1 heavy chain	Homo sapiens (human)
membrane	Kinesin-1 heavy chain	Homo sapiens (human)
vesicle	Kinesin-1 heavy chain	Homo sapiens (human)
dendrite cytoplasm	Kinesin-1 heavy chain	Homo sapiens (human)
centriolar satellite	Kinesin-1 heavy chain	Homo sapiens (human)
ciliary rootlet	Kinesin-1 heavy chain	Homo sapiens (human)
phagocytic vesicle	Kinesin-1 heavy chain	Homo sapiens (human)
perinuclear region of cytoplasm	Kinesin-1 heavy chain	Homo sapiens (human)
cytolytic granule membrane	Kinesin-1 heavy chain	Homo sapiens (human)
axon cytoplasm	Kinesin-1 heavy chain	Homo sapiens (human)
microtubule	Kinesin-1 heavy chain	Homo sapiens (human)
kinesin complex	Kinesin-1 heavy chain	Homo sapiens (human)
cytoplasm	Dual specificity protein kinase TTK	Homo sapiens (human)
spindle	Dual specificity protein kinase TTK	Homo sapiens (human)
membrane	Dual specificity protein kinase TTK	Homo sapiens (human)
kinetochore	Dual specificity protein kinase TTK	Homo sapiens (human)
nucleus	Dual specificity protein kinase TTK	Homo sapiens (human)
chromosome, telomeric region	DNA replication licensing factor MCM4	Homo sapiens (human)
nucleus	DNA replication licensing factor MCM4	Homo sapiens (human)
nucleoplasm	DNA replication licensing factor MCM4	Homo sapiens (human)
membrane	DNA replication licensing factor MCM4	Homo sapiens (human)
MCM complex	DNA replication licensing factor MCM4	Homo sapiens (human)
CMG complex	DNA replication licensing factor MCM4	Homo sapiens (human)
nucleus	DNA replication licensing factor MCM4	Homo sapiens (human)
postsynaptic actin cytoskeleton	Myosin-10	Homo sapiens (human)
stress fiber	Myosin-10	Homo sapiens (human)
nucleus	Myosin-10	Homo sapiens (human)
cytoplasm	Myosin-10	Homo sapiens (human)
cytosol	Myosin-10	Homo sapiens (human)
cell cortex	Myosin-10	Homo sapiens (human)
lamellipodium	Myosin-10	Homo sapiens (human)
midbody	Myosin-10	Homo sapiens (human)
cleavage furrow	Myosin-10	Homo sapiens (human)
actomyosin	Myosin-10	Homo sapiens (human)
extracellular exosome	Myosin-10	Homo sapiens (human)
myosin II filament	Myosin-10	Homo sapiens (human)
myosin complex	Myosin-10	Homo sapiens (human)
myosin II complex	Myosin-10	Homo sapiens (human)
myosin filament	Myosin-10	Homo sapiens (human)
cytoplasm	Myosin-10	Homo sapiens (human)
extracellular region	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
nucleoplasm	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
cytosol	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
receptor complex	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 3	Homo sapiens (human)
extracellular region	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
nucleus	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endosome	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
early endosome	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endoplasmic reticulum	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
Golgi apparatus	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
external side of plasma membrane	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell junction	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
membrane raft	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
anchoring junction	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
sorting endosome	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
receptor complex	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
extracellular region	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
nucleus	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
mitochondrion	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
early endosome	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
late endosome	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
peroxisomal membrane	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
endoplasmic reticulum	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
Golgi apparatus	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
microtubule	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
cell-cell junction	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
focal adhesion	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
cytoplasmic side of plasma membrane	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
perinuclear region of cytoplasm	Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)
endoplasmic reticulum	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
endoplasmic reticulum lumen	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
plasma membrane	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
endosome membrane	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
receptor complex	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
plasma membrane	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
caveola	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
external side of plasma membrane	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
membrane	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
dendrite	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
neuronal cell body	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
HFE-transferrin receptor complex	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
receptor complex	Bone morphogenetic protein receptor type-1A	Homo sapiens (human)
cytosol	Activin receptor type-1B	Homo sapiens (human)
plasma membrane	Activin receptor type-1B	Homo sapiens (human)
cell surface	Activin receptor type-1B	Homo sapiens (human)
receptor complex	Activin receptor type-1B	Homo sapiens (human)
activin receptor complex	Activin receptor type-1B	Homo sapiens (human)
plasma membrane	Activin receptor type-1B	Homo sapiens (human)
nucleus	TGF-beta receptor type-1	Homo sapiens (human)
endosome	TGF-beta receptor type-1	Homo sapiens (human)
plasma membrane	TGF-beta receptor type-1	Homo sapiens (human)
bicellular tight junction	TGF-beta receptor type-1	Homo sapiens (human)
cell surface	TGF-beta receptor type-1	Homo sapiens (human)
membrane raft	TGF-beta receptor type-1	Homo sapiens (human)
transforming growth factor beta ligand-receptor complex	TGF-beta receptor type-1	Homo sapiens (human)
receptor complex	TGF-beta receptor type-1	Homo sapiens (human)
plasma membrane	TGF-beta receptor type-1	Homo sapiens (human)
activin receptor complex	TGF-beta receptor type-1	Homo sapiens (human)
extracellular region	TGF-beta receptor type-2	Homo sapiens (human)
cytosol	TGF-beta receptor type-2	Homo sapiens (human)
plasma membrane	TGF-beta receptor type-2	Homo sapiens (human)
caveola	TGF-beta receptor type-2	Homo sapiens (human)
external side of plasma membrane	TGF-beta receptor type-2	Homo sapiens (human)
membrane	TGF-beta receptor type-2	Homo sapiens (human)
membrane raft	TGF-beta receptor type-2	Homo sapiens (human)
transforming growth factor beta ligand-receptor complex	TGF-beta receptor type-2	Homo sapiens (human)
receptor complex	TGF-beta receptor type-2	Homo sapiens (human)
plasma membrane	TGF-beta receptor type-2	Homo sapiens (human)
mitochondrion	Electron transfer flavoprotein subunit beta	Homo sapiens (human)
mitochondrial matrix	Electron transfer flavoprotein subunit beta	Homo sapiens (human)
electron transfer flavoprotein complex	Electron transfer flavoprotein subunit beta	Homo sapiens (human)
mitochondrion	Electron transfer flavoprotein subunit beta	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase CSK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase CSK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase CSK	Homo sapiens (human)
cell-cell junction	Tyrosine-protein kinase CSK	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase CSK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase CSK	Homo sapiens (human)
mitochondrial matrix	Glycine--tRNA ligase	Homo sapiens (human)
cytosol	Glycine--tRNA ligase	Homo sapiens (human)
secretory granule	Glycine--tRNA ligase	Homo sapiens (human)
axon	Glycine--tRNA ligase	Homo sapiens (human)
extracellular exosome	Glycine--tRNA ligase	Homo sapiens (human)
cytoplasm	Glycine--tRNA ligase	Homo sapiens (human)
mitochondrion	Glycine--tRNA ligase	Homo sapiens (human)
Golgi membrane	Protein kinase C iota type	Homo sapiens (human)
nucleus	Protein kinase C iota type	Homo sapiens (human)
nucleoplasm	Protein kinase C iota type	Homo sapiens (human)
endosome	Protein kinase C iota type	Homo sapiens (human)
cytosol	Protein kinase C iota type	Homo sapiens (human)
plasma membrane	Protein kinase C iota type	Homo sapiens (human)
brush border	Protein kinase C iota type	Homo sapiens (human)
bicellular tight junction	Protein kinase C iota type	Homo sapiens (human)
microtubule cytoskeleton	Protein kinase C iota type	Homo sapiens (human)
apical plasma membrane	Protein kinase C iota type	Homo sapiens (human)
cell leading edge	Protein kinase C iota type	Homo sapiens (human)
Schmidt-Lanterman incisure	Protein kinase C iota type	Homo sapiens (human)
intercellular bridge	Protein kinase C iota type	Homo sapiens (human)
extracellular exosome	Protein kinase C iota type	Homo sapiens (human)
tight junction	Protein kinase C iota type	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Protein kinase C iota type	Homo sapiens (human)
glutamatergic synapse	Protein kinase C iota type	Homo sapiens (human)
PAR polarity complex	Protein kinase C iota type	Homo sapiens (human)
nuclear exosome (RNase complex)	Exosome RNA helicase MTR4	Homo sapiens (human)
exosome (RNase complex)	Exosome RNA helicase MTR4	Homo sapiens (human)
nucleus	Exosome RNA helicase MTR4	Homo sapiens (human)
nucleoplasm	Exosome RNA helicase MTR4	Homo sapiens (human)
nucleolus	Exosome RNA helicase MTR4	Homo sapiens (human)
nuclear speck	Exosome RNA helicase MTR4	Homo sapiens (human)
TRAMP complex	Exosome RNA helicase MTR4	Homo sapiens (human)
catalytic step 2 spliceosome	Exosome RNA helicase MTR4	Homo sapiens (human)
nucleus	Exosome RNA helicase MTR4	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Tec	Homo sapiens (human)
cytoskeleton	Tyrosine-protein kinase Tec	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Tec	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Tec	Homo sapiens (human)
cytosol	Tyrosine-protein kinase ABL2	Homo sapiens (human)
actin cytoskeleton	Tyrosine-protein kinase ABL2	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase ABL2	Homo sapiens (human)
extracellular region	Tyrosine-protein kinase FRK	Homo sapiens (human)
nucleus	Tyrosine-protein kinase FRK	Homo sapiens (human)
nucleoplasm	Tyrosine-protein kinase FRK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase FRK	Homo sapiens (human)
azurophil granule lumen	Tyrosine-protein kinase FRK	Homo sapiens (human)
specific granule lumen	Tyrosine-protein kinase FRK	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase FRK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase FRK	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase SYK	Homo sapiens (human)
nucleus	Tyrosine-protein kinase SYK	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase SYK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase SYK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase SYK	Homo sapiens (human)
early phagosome	Tyrosine-protein kinase SYK	Homo sapiens (human)
B cell receptor complex	Tyrosine-protein kinase SYK	Homo sapiens (human)
protein-containing complex	Tyrosine-protein kinase SYK	Homo sapiens (human)
T cell receptor complex	Tyrosine-protein kinase SYK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase SYK	Homo sapiens (human)
proteasome complex	26S proteasome regulatory subunit 6B	Homo sapiens (human)
nucleus	26S proteasome regulatory subunit 6B	Homo sapiens (human)
nucleoplasm	26S proteasome regulatory subunit 6B	Homo sapiens (human)
cytosol	26S proteasome regulatory subunit 6B	Homo sapiens (human)
membrane	26S proteasome regulatory subunit 6B	Homo sapiens (human)
inclusion body	26S proteasome regulatory subunit 6B	Homo sapiens (human)
synapse	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteasome accessory complex	26S proteasome regulatory subunit 6B	Homo sapiens (human)
cytosolic proteasome complex	26S proteasome regulatory subunit 6B	Homo sapiens (human)
proteasome regulatory particle, base subcomplex	26S proteasome regulatory subunit 6B	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 8	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 8	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 8	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 8	Homo sapiens (human)
axon	Mitogen-activated protein kinase 8	Homo sapiens (human)
synapse	Mitogen-activated protein kinase 8	Homo sapiens (human)
basal dendrite	Mitogen-activated protein kinase 8	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 8	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 9	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 9	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 9	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase 9	Homo sapiens (human)
nuclear speck	Mitogen-activated protein kinase 9	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Mitogen-activated protein kinase 9	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 9	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 9	Homo sapiens (human)
cytoplasm	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
nucleoplasm	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
membrane	Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)
photoreceptor outer segment	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
photoreceptor inner segment	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
nucleoplasm	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
lysosome	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
autophagosome	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
cytosol	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)
mRNA cleavage and polyadenylation specificity factor complex	Casein kinase I isoform alpha	Homo sapiens (human)
keratin filament	Casein kinase I isoform alpha	Homo sapiens (human)
kinetochore	Casein kinase I isoform alpha	Homo sapiens (human)
centrosome	Casein kinase I isoform alpha	Homo sapiens (human)
spindle	Casein kinase I isoform alpha	Homo sapiens (human)
cytosol	Casein kinase I isoform alpha	Homo sapiens (human)
cilium	Casein kinase I isoform alpha	Homo sapiens (human)
membrane	Casein kinase I isoform alpha	Homo sapiens (human)
nuclear speck	Casein kinase I isoform alpha	Homo sapiens (human)
beta-catenin destruction complex	Casein kinase I isoform alpha	Homo sapiens (human)
ciliary basal body	Casein kinase I isoform alpha	Homo sapiens (human)
cytoplasm	Casein kinase I isoform alpha	Homo sapiens (human)
nucleus	Casein kinase I isoform alpha	Homo sapiens (human)
nucleus	Casein kinase I isoform delta	Homo sapiens (human)
nucleoplasm	Casein kinase I isoform delta	Homo sapiens (human)
Golgi apparatus	Casein kinase I isoform delta	Homo sapiens (human)
centrosome	Casein kinase I isoform delta	Homo sapiens (human)
spindle	Casein kinase I isoform delta	Homo sapiens (human)
cytosol	Casein kinase I isoform delta	Homo sapiens (human)
spindle microtubule	Casein kinase I isoform delta	Homo sapiens (human)
plasma membrane	Casein kinase I isoform delta	Homo sapiens (human)
endoplasmic reticulum-Golgi intermediate compartment membrane	Casein kinase I isoform delta	Homo sapiens (human)
ciliary basal body	Casein kinase I isoform delta	Homo sapiens (human)
perinuclear region of cytoplasm	Casein kinase I isoform delta	Homo sapiens (human)
nucleus	Casein kinase I isoform delta	Homo sapiens (human)
cytoplasm	Casein kinase I isoform delta	Homo sapiens (human)
spindle microtubule	Casein kinase I isoform delta	Homo sapiens (human)
nucleus	MAP kinase-activated protein kinase 2	Homo sapiens (human)
nucleoplasm	MAP kinase-activated protein kinase 2	Homo sapiens (human)
cytoplasm	MAP kinase-activated protein kinase 2	Homo sapiens (human)
centrosome	MAP kinase-activated protein kinase 2	Homo sapiens (human)
cytosol	MAP kinase-activated protein kinase 2	Homo sapiens (human)
extracellular exosome	MAP kinase-activated protein kinase 2	Homo sapiens (human)
nucleus	MAP kinase-activated protein kinase 2	Homo sapiens (human)
cytoplasm	MAP kinase-activated protein kinase 2	Homo sapiens (human)
mitochondrion	Elongation factor Tu, mitochondrial	Homo sapiens (human)
mitochondrial outer membrane	Elongation factor Tu, mitochondrial	Homo sapiens (human)
membrane	Elongation factor Tu, mitochondrial	Homo sapiens (human)
mitochondrial nucleoid	Elongation factor Tu, mitochondrial	Homo sapiens (human)
synapse	Elongation factor Tu, mitochondrial	Homo sapiens (human)
extracellular exosome	Elongation factor Tu, mitochondrial	Homo sapiens (human)
mitochondrion	Elongation factor Tu, mitochondrial	Homo sapiens (human)
cytoplasm	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytosol	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytoplasm	Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)
nucleus	Casein kinase I isoform epsilon	Homo sapiens (human)
nucleoplasm	Casein kinase I isoform epsilon	Homo sapiens (human)
cytoplasm	Casein kinase I isoform epsilon	Homo sapiens (human)
cytosol	Casein kinase I isoform epsilon	Homo sapiens (human)
growth cone	Casein kinase I isoform epsilon	Homo sapiens (human)
neuronal cell body	Casein kinase I isoform epsilon	Homo sapiens (human)
ribonucleoprotein complex	Casein kinase I isoform epsilon	Homo sapiens (human)
cytoplasm	Casein kinase I isoform epsilon	Homo sapiens (human)
nucleus	Casein kinase I isoform epsilon	Homo sapiens (human)
nucleoplasm	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
nucleolus	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrion	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrial inner membrane	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrial matrix	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrial membrane	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
mitochondrial nucleoid	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK1	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK2	Homo sapiens (human)
nucleoplasm	Dual specificity protein kinase CLK2	Homo sapiens (human)
nuclear body	Dual specificity protein kinase CLK2	Homo sapiens (human)
nuclear speck	Dual specificity protein kinase CLK2	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK2	Homo sapiens (human)
acrosomal vesicle	Dual specificity protein kinase CLK3	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK3	Homo sapiens (human)
nucleoplasm	Dual specificity protein kinase CLK3	Homo sapiens (human)
membrane	Dual specificity protein kinase CLK3	Homo sapiens (human)
nuclear speck	Dual specificity protein kinase CLK3	Homo sapiens (human)
intermediate filament cytoskeleton	Dual specificity protein kinase CLK3	Homo sapiens (human)
mitochondrion	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cytosol	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
beta-catenin destruction complex	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
neuronal cell body	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
apical dendrite	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
postsynapse	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
proximal dendrite	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cytoplasm	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
nucleus	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
axon	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
cytosol	Glycogen synthase kinase-3 alpha	Homo sapiens (human)
glutamatergic synapse	Glycogen synthase kinase-3 beta	Homo sapiens (human)
nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
nucleoplasm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cytoplasm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
mitochondrion	Glycogen synthase kinase-3 beta	Homo sapiens (human)
centrosome	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cytosol	Glycogen synthase kinase-3 beta	Homo sapiens (human)
plasma membrane	Glycogen synthase kinase-3 beta	Homo sapiens (human)
axon	Glycogen synthase kinase-3 beta	Homo sapiens (human)
dendrite	Glycogen synthase kinase-3 beta	Homo sapiens (human)
beta-catenin destruction complex	Glycogen synthase kinase-3 beta	Homo sapiens (human)
presynapse	Glycogen synthase kinase-3 beta	Homo sapiens (human)
postsynapse	Glycogen synthase kinase-3 beta	Homo sapiens (human)
Wnt signalosome	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cytosol	Glycogen synthase kinase-3 beta	Homo sapiens (human)
axon	Glycogen synthase kinase-3 beta	Homo sapiens (human)
nucleus	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cytoplasm	Glycogen synthase kinase-3 beta	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 7	Homo sapiens (human)
fibrillar center	Cyclin-dependent kinase 7	Homo sapiens (human)
male germ cell nucleus	Cyclin-dependent kinase 7	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 7	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 7	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 7	Homo sapiens (human)
plasma membrane	Cyclin-dependent kinase 7	Homo sapiens (human)
perinuclear region of cytoplasm	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription factor TFIIH core complex	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription factor TFIIH holo complex	Cyclin-dependent kinase 7	Homo sapiens (human)
CAK-ERCC2 complex	Cyclin-dependent kinase 7	Homo sapiens (human)
transcription factor TFIIK complex	Cyclin-dependent kinase 7	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 7	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 7	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 9	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 9	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 9	Homo sapiens (human)
cyclin/CDK positive transcription elongation factor complex	Cyclin-dependent kinase 9	Homo sapiens (human)
membrane	Cyclin-dependent kinase 9	Homo sapiens (human)
PML body	Cyclin-dependent kinase 9	Homo sapiens (human)
cytoplasmic ribonucleoprotein granule	Cyclin-dependent kinase 9	Homo sapiens (human)
transcription elongation factor complex	Cyclin-dependent kinase 9	Homo sapiens (human)
P-TEFb complex	Cyclin-dependent kinase 9	Homo sapiens (human)
photoreceptor outer segment	Ras-related protein Rab-27A	Homo sapiens (human)
extracellular region	Ras-related protein Rab-27A	Homo sapiens (human)
lysosome	Ras-related protein Rab-27A	Homo sapiens (human)
late endosome	Ras-related protein Rab-27A	Homo sapiens (human)
cytosol	Ras-related protein Rab-27A	Homo sapiens (human)
dendrite	Ras-related protein Rab-27A	Homo sapiens (human)
multivesicular body membrane	Ras-related protein Rab-27A	Homo sapiens (human)
Weibel-Palade body	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome membrane	Ras-related protein Rab-27A	Homo sapiens (human)
specific granule lumen	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome	Ras-related protein Rab-27A	Homo sapiens (human)
extracellular exosome	Ras-related protein Rab-27A	Homo sapiens (human)
exocytic vesicle	Ras-related protein Rab-27A	Homo sapiens (human)
exocytic vesicle	Ras-related protein Rab-27A	Homo sapiens (human)
apical plasma membrane	Ras-related protein Rab-27A	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-27A	Homo sapiens (human)
secretory granule	Ras-related protein Rab-27A	Homo sapiens (human)
melanosome	Ras-related protein Rab-27A	Homo sapiens (human)
cytoplasm	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cell surface	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
nucleoplasm	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
lipid droplet	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
cytosol	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
endosome membrane	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
protein-containing complex	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
nucleus	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
nucleolus	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
synapse	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
condensed nuclear chromosome	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
microtubule	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
midbody	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
axon	Serine/threonine-protein kinase Nek3	Homo sapiens (human)
cytoplasm	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
nucleoplasm	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
cytoskeleton	Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)
spindle microtubule	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
synaptonemal complex	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centriole	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
spindle	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
microtubule cytoskeleton	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
midbody	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centriolar satellite	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
spindle midzone	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
mitotic spindle pole	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
chromatin	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
outer kinetochore	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
kinetochore	Serine/threonine-protein kinase PLK1	Homo sapiens (human)
postsynapse	LIM domain kinase 1	Homo sapiens (human)
glutamatergic synapse	LIM domain kinase 1	Homo sapiens (human)
male germ cell nucleus	LIM domain kinase 1	Homo sapiens (human)
cytoplasm	LIM domain kinase 1	Homo sapiens (human)
cytosol	LIM domain kinase 1	Homo sapiens (human)
cytoskeleton	LIM domain kinase 1	Homo sapiens (human)
focal adhesion	LIM domain kinase 1	Homo sapiens (human)
membrane	LIM domain kinase 1	Homo sapiens (human)
nuclear speck	LIM domain kinase 1	Homo sapiens (human)
lamellipodium	LIM domain kinase 1	Homo sapiens (human)
neuron projection	LIM domain kinase 1	Homo sapiens (human)
nucleus	LIM domain kinase 1	Homo sapiens (human)
neuron projection	LIM domain kinase 1	Homo sapiens (human)
cytoplasm	LIM domain kinase 1	Homo sapiens (human)
nucleus	LIM domain kinase 2	Homo sapiens (human)
cytoplasm	LIM domain kinase 2	Homo sapiens (human)
cis-Golgi network	LIM domain kinase 2	Homo sapiens (human)
centrosome	LIM domain kinase 2	Homo sapiens (human)
perinuclear region of cytoplasm	LIM domain kinase 2	Homo sapiens (human)
mitotic spindle	LIM domain kinase 2	Homo sapiens (human)
nucleus	LIM domain kinase 2	Homo sapiens (human)
cytoplasm	LIM domain kinase 2	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 10	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 10	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 10	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 10	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase 10	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 10	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 10	Homo sapiens (human)
nucleus	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytoplasm	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytosol	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
extracellular space	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
cytosol	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
nuclear body	Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
nucleoplasm	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cytosol	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
membrane	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
nucleotide-activated protein kinase complex	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
cytoplasm	5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)
extracellular region	Ephrin type-B receptor 3	Homo sapiens (human)
cytosol	Ephrin type-B receptor 3	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 3	Homo sapiens (human)
dendrite	Ephrin type-B receptor 3	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 3	Homo sapiens (human)
rough endoplasmic reticulum	Ephrin type-A receptor 5	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 5	Homo sapiens (human)
external side of plasma membrane	Ephrin type-A receptor 5	Homo sapiens (human)
axon	Ephrin type-A receptor 5	Homo sapiens (human)
dendrite	Ephrin type-A receptor 5	Homo sapiens (human)
neuronal cell body	Ephrin type-A receptor 5	Homo sapiens (human)
perinuclear region of cytoplasm	Ephrin type-A receptor 5	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 5	Homo sapiens (human)
dendrite	Ephrin type-A receptor 5	Homo sapiens (human)
extracellular region	Ephrin type-B receptor 4	Homo sapiens (human)
cytosol	Ephrin type-B receptor 4	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 4	Homo sapiens (human)
extracellular exosome	Ephrin type-B receptor 4	Homo sapiens (human)
receptor complex	Ephrin type-B receptor 4	Homo sapiens (human)
plasma membrane	Ephrin type-B receptor 4	Homo sapiens (human)
cytoplasm	Ephrin type-A receptor 4	Homo sapiens (human)
mitochondrial outer membrane	Ephrin type-A receptor 4	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 4	Homo sapiens (human)
adherens junction	Ephrin type-A receptor 4	Homo sapiens (human)
cell surface	Ephrin type-A receptor 4	Homo sapiens (human)
filopodium	Ephrin type-A receptor 4	Homo sapiens (human)
axon	Ephrin type-A receptor 4	Homo sapiens (human)
dendrite	Ephrin type-A receptor 4	Homo sapiens (human)
neuromuscular junction	Ephrin type-A receptor 4	Homo sapiens (human)
early endosome membrane	Ephrin type-A receptor 4	Homo sapiens (human)
presynaptic membrane	Ephrin type-A receptor 4	Homo sapiens (human)
dendritic spine	Ephrin type-A receptor 4	Homo sapiens (human)
dendritic shaft	Ephrin type-A receptor 4	Homo sapiens (human)
perikaryon	Ephrin type-A receptor 4	Homo sapiens (human)
axon terminus	Ephrin type-A receptor 4	Homo sapiens (human)
axonal growth cone	Ephrin type-A receptor 4	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Ephrin type-A receptor 4	Homo sapiens (human)
postsynaptic density membrane	Ephrin type-A receptor 4	Homo sapiens (human)
glutamatergic synapse	Ephrin type-A receptor 4	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 4	Homo sapiens (human)
dendrite	Ephrin type-A receptor 4	Homo sapiens (human)
mitochondrial intermembrane space	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
extracellular exosome	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
sperm mitochondrial sheath	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
cytoplasm	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
mitochondrion	Adenylate kinase 2, mitochondrial	Homo sapiens (human)
nucleoplasm	Adenosine kinase	Homo sapiens (human)
cytosol	Adenosine kinase	Homo sapiens (human)
plasma membrane	Adenosine kinase	Homo sapiens (human)
nucleus	Adenosine kinase	Homo sapiens (human)
cytosol	Adenosine kinase	Homo sapiens (human)
virion membrane	Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus
exocyst	Ras-related protein Rab-10	Homo sapiens (human)
plasma membrane	Ras-related protein Rab-10	Homo sapiens (human)
Golgi membrane	Ras-related protein Rab-10	Homo sapiens (human)
endosome	Ras-related protein Rab-10	Homo sapiens (human)
endoplasmic reticulum membrane	Ras-related protein Rab-10	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-10	Homo sapiens (human)
trans-Golgi network	Ras-related protein Rab-10	Homo sapiens (human)
cytosol	Ras-related protein Rab-10	Homo sapiens (human)
cytoskeleton	Ras-related protein Rab-10	Homo sapiens (human)
plasma membrane	Ras-related protein Rab-10	Homo sapiens (human)
adherens junction	Ras-related protein Rab-10	Homo sapiens (human)
focal adhesion	Ras-related protein Rab-10	Homo sapiens (human)
cilium	Ras-related protein Rab-10	Homo sapiens (human)
endosome membrane	Ras-related protein Rab-10	Homo sapiens (human)
cytoplasmic vesicle membrane	Ras-related protein Rab-10	Homo sapiens (human)
secretory granule membrane	Ras-related protein Rab-10	Homo sapiens (human)
phagocytic vesicle membrane	Ras-related protein Rab-10	Homo sapiens (human)
insulin-responsive compartment	Ras-related protein Rab-10	Homo sapiens (human)
perinuclear region of cytoplasm	Ras-related protein Rab-10	Homo sapiens (human)
recycling endosome	Ras-related protein Rab-10	Homo sapiens (human)
recycling endosome membrane	Ras-related protein Rab-10	Homo sapiens (human)
extracellular exosome	Ras-related protein Rab-10	Homo sapiens (human)
exocytic vesicle	Ras-related protein Rab-10	Homo sapiens (human)
endoplasmic reticulum tubular network	Ras-related protein Rab-10	Homo sapiens (human)
recycling endosome	Ras-related protein Rab-10	Homo sapiens (human)
secretory vesicle	Ras-related protein Rab-10	Homo sapiens (human)
membrane	Ras-related protein Rab-10	Homo sapiens (human)
Golgi apparatus	Ras-related protein Rab-10	Homo sapiens (human)
nucleus	Actin-related protein 3	Homo sapiens (human)
cytoplasm	Actin-related protein 3	Homo sapiens (human)
cytosol	Actin-related protein 3	Homo sapiens (human)
brush border	Actin-related protein 3	Homo sapiens (human)
cell-cell junction	Actin-related protein 3	Homo sapiens (human)
focal adhesion	Actin-related protein 3	Homo sapiens (human)
actin cytoskeleton	Actin-related protein 3	Homo sapiens (human)
membrane	Actin-related protein 3	Homo sapiens (human)
lamellipodium	Actin-related protein 3	Homo sapiens (human)
site of double-strand break	Actin-related protein 3	Homo sapiens (human)
extracellular exosome	Actin-related protein 3	Homo sapiens (human)
Arp2/3 protein complex	Actin-related protein 3	Homo sapiens (human)
extracellular region	Actin-related protein 2	Homo sapiens (human)
nucleus	Actin-related protein 2	Homo sapiens (human)
cytoplasm	Actin-related protein 2	Homo sapiens (human)
cytosol	Actin-related protein 2	Homo sapiens (human)
focal adhesion	Actin-related protein 2	Homo sapiens (human)
actin cytoskeleton	Actin-related protein 2	Homo sapiens (human)
membrane	Actin-related protein 2	Homo sapiens (human)
actin cap	Actin-related protein 2	Homo sapiens (human)
azurophil granule lumen	Actin-related protein 2	Homo sapiens (human)
site of double-strand break	Actin-related protein 2	Homo sapiens (human)
cell projection	Actin-related protein 2	Homo sapiens (human)
extracellular exosome	Actin-related protein 2	Homo sapiens (human)
ficolin-1-rich granule lumen	Actin-related protein 2	Homo sapiens (human)
Arp2/3 protein complex	Actin-related protein 2	Homo sapiens (human)
cell cortex	Actin-related protein 2	Homo sapiens (human)
Flemming body	GTP-binding nuclear protein Ran	Homo sapiens (human)
male germ cell nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
manchette	GTP-binding nuclear protein Ran	Homo sapiens (human)
nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
nuclear envelope	GTP-binding nuclear protein Ran	Homo sapiens (human)
nucleoplasm	GTP-binding nuclear protein Ran	Homo sapiens (human)
nucleolus	GTP-binding nuclear protein Ran	Homo sapiens (human)
cytoplasm	GTP-binding nuclear protein Ran	Homo sapiens (human)
centriole	GTP-binding nuclear protein Ran	Homo sapiens (human)
cytosol	GTP-binding nuclear protein Ran	Homo sapiens (human)
membrane	GTP-binding nuclear protein Ran	Homo sapiens (human)
midbody	GTP-binding nuclear protein Ran	Homo sapiens (human)
sperm flagellum	GTP-binding nuclear protein Ran	Homo sapiens (human)
melanosome	GTP-binding nuclear protein Ran	Homo sapiens (human)
recycling endosome	GTP-binding nuclear protein Ran	Homo sapiens (human)
extracellular exosome	GTP-binding nuclear protein Ran	Homo sapiens (human)
chromatin	GTP-binding nuclear protein Ran	Homo sapiens (human)
nuclear pore	GTP-binding nuclear protein Ran	Homo sapiens (human)
protein-containing complex	GTP-binding nuclear protein Ran	Homo sapiens (human)
RNA nuclear export complex	GTP-binding nuclear protein Ran	Homo sapiens (human)
nucleus	GTP-binding nuclear protein Ran	Homo sapiens (human)
cytoplasm	GTP-binding nuclear protein Ran	Homo sapiens (human)
cytosol	Casein kinase I isoform gamma-2	Homo sapiens (human)
cell cortex	Casein kinase I isoform gamma-2	Homo sapiens (human)
membrane	Casein kinase I isoform gamma-2	Homo sapiens (human)
cytoplasm	Casein kinase I isoform gamma-2	Homo sapiens (human)
plasma membrane	Casein kinase I isoform gamma-2	Homo sapiens (human)
nucleus	Casein kinase I isoform gamma-2	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 3	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 3	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 3	Homo sapiens (human)
ruffle	Cyclin-dependent kinase 6	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 6	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 6	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 6	Homo sapiens (human)
centrosome	Cyclin-dependent kinase 6	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin D1-CDK6 complex	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin D3-CDK6 complex	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 6	Homo sapiens (human)
cyclin D2-CDK6 complex	Cyclin-dependent kinase 6	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 6	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 6	Homo sapiens (human)
microtubule	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent-like kinase 5	Homo sapiens (human)
nucleus	Cyclin-dependent-like kinase 5	Homo sapiens (human)
nucleoplasm	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cytoplasm	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cytosol	Cyclin-dependent-like kinase 5	Homo sapiens (human)
plasma membrane	Cyclin-dependent-like kinase 5	Homo sapiens (human)
postsynaptic density	Cyclin-dependent-like kinase 5	Homo sapiens (human)
membrane	Cyclin-dependent-like kinase 5	Homo sapiens (human)
protein kinase 5 complex	Cyclin-dependent-like kinase 5	Homo sapiens (human)
lamellipodium	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cell junction	Cyclin-dependent-like kinase 5	Homo sapiens (human)
filopodium	Cyclin-dependent-like kinase 5	Homo sapiens (human)
axon	Cyclin-dependent-like kinase 5	Homo sapiens (human)
dendrite	Cyclin-dependent-like kinase 5	Homo sapiens (human)
growth cone	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuromuscular junction	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuron projection	Cyclin-dependent-like kinase 5	Homo sapiens (human)
neuronal cell body	Cyclin-dependent-like kinase 5	Homo sapiens (human)
perikaryon	Cyclin-dependent-like kinase 5	Homo sapiens (human)
presynapse	Cyclin-dependent-like kinase 5	Homo sapiens (human)
nucleus	Cyclin-dependent-like kinase 5	Homo sapiens (human)
cytoplasm	Cyclin-dependent-like kinase 5	Homo sapiens (human)
synaptic vesicle	Cyclin-dependent kinase 16	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 16	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 16	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 16	Homo sapiens (human)
plasma membrane	Cyclin-dependent kinase 16	Homo sapiens (human)
cytoplasmic side of plasma membrane	Cyclin-dependent kinase 16	Homo sapiens (human)
microtubule cytoskeleton	Cyclin-dependent kinase 16	Homo sapiens (human)
neuron projection	Cyclin-dependent kinase 16	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 16	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 16	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 17	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 17	Homo sapiens (human)
nucleus	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
cytoplasm	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
cytosol	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
membrane	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
extracellular exosome	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
membrane	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
6-phosphofructokinase complex	ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)
nucleus	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
mitochondrion	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
early endosome	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
late endosome	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
endoplasmic reticulum	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
Golgi apparatus	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
centrosome	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
cytosol	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
plasma membrane	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
focal adhesion	Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)
stress fiber	Angiopoietin-1 receptor	Homo sapiens (human)
actin filament	Angiopoietin-1 receptor	Homo sapiens (human)
extracellular region	Angiopoietin-1 receptor	Homo sapiens (human)
cytoplasm	Angiopoietin-1 receptor	Homo sapiens (human)
plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
microvillus	Angiopoietin-1 receptor	Homo sapiens (human)
cell-cell junction	Angiopoietin-1 receptor	Homo sapiens (human)
focal adhesion	Angiopoietin-1 receptor	Homo sapiens (human)
basal plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
cell surface	Angiopoietin-1 receptor	Homo sapiens (human)
basolateral plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
apical plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
centriolar satellite	Angiopoietin-1 receptor	Homo sapiens (human)
membrane raft	Angiopoietin-1 receptor	Homo sapiens (human)
plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
receptor complex	Angiopoietin-1 receptor	Homo sapiens (human)
nucleolus	DNA topoisomerase 2-beta	Homo sapiens (human)
heterochromatin	DNA topoisomerase 2-beta	Homo sapiens (human)
nucleus	DNA topoisomerase 2-beta	Homo sapiens (human)
nucleoplasm	DNA topoisomerase 2-beta	Homo sapiens (human)
nucleolus	DNA topoisomerase 2-beta	Homo sapiens (human)
cytosol	DNA topoisomerase 2-beta	Homo sapiens (human)
ribonucleoprotein complex	DNA topoisomerase 2-beta	Homo sapiens (human)
nucleus	DNA topoisomerase 2-beta	Homo sapiens (human)
immunological synapse	Protein kinase C theta type	Homo sapiens (human)
cytosol	Protein kinase C theta type	Homo sapiens (human)
plasma membrane	Protein kinase C theta type	Homo sapiens (human)
aggresome	Protein kinase C theta type	Homo sapiens (human)
centriolar satellite	Protein kinase C theta type	Homo sapiens (human)
plasma membrane	Activin receptor type-1	Homo sapiens (human)
apical part of cell	Activin receptor type-1	Homo sapiens (human)
activin receptor complex	Activin receptor type-1	Homo sapiens (human)
BMP receptor complex	Activin receptor type-1	Homo sapiens (human)
plasma membrane	Activin receptor type-1	Homo sapiens (human)
stress fiber	Macrophage-stimulating protein receptor	Homo sapiens (human)
vacuole	Macrophage-stimulating protein receptor	Homo sapiens (human)
plasma membrane	Macrophage-stimulating protein receptor	Homo sapiens (human)
cell surface	Macrophage-stimulating protein receptor	Homo sapiens (human)
receptor complex	Macrophage-stimulating protein receptor	Homo sapiens (human)
plasma membrane	Macrophage-stimulating protein receptor	Homo sapiens (human)
stress fiber	Focal adhesion kinase 1	Homo sapiens (human)
nucleus	Focal adhesion kinase 1	Homo sapiens (human)
cytoplasm	Focal adhesion kinase 1	Homo sapiens (human)
centrosome	Focal adhesion kinase 1	Homo sapiens (human)
cytosol	Focal adhesion kinase 1	Homo sapiens (human)
cytoskeleton	Focal adhesion kinase 1	Homo sapiens (human)
plasma membrane	Focal adhesion kinase 1	Homo sapiens (human)
focal adhesion	Focal adhesion kinase 1	Homo sapiens (human)
cell cortex	Focal adhesion kinase 1	Homo sapiens (human)
ciliary basal body	Focal adhesion kinase 1	Homo sapiens (human)
intracellular membrane-bounded organelle	Focal adhesion kinase 1	Homo sapiens (human)
perinuclear region of cytoplasm	Focal adhesion kinase 1	Homo sapiens (human)
plasma membrane	Focal adhesion kinase 1	Homo sapiens (human)
focal adhesion	Focal adhesion kinase 1	Homo sapiens (human)
dendritic spine	Focal adhesion kinase 1	Homo sapiens (human)
stress fiber	Protein kinase C zeta type	Homo sapiens (human)
nuclear envelope	Protein kinase C zeta type	Homo sapiens (human)
cytoplasm	Protein kinase C zeta type	Homo sapiens (human)
endosome	Protein kinase C zeta type	Homo sapiens (human)
microtubule organizing center	Protein kinase C zeta type	Homo sapiens (human)
cytosol	Protein kinase C zeta type	Homo sapiens (human)
plasma membrane	Protein kinase C zeta type	Homo sapiens (human)
cell-cell junction	Protein kinase C zeta type	Homo sapiens (human)
bicellular tight junction	Protein kinase C zeta type	Homo sapiens (human)
postsynaptic density	Protein kinase C zeta type	Homo sapiens (human)
membrane	Protein kinase C zeta type	Homo sapiens (human)
apical plasma membrane	Protein kinase C zeta type	Homo sapiens (human)
nuclear matrix	Protein kinase C zeta type	Homo sapiens (human)
cell junction	Protein kinase C zeta type	Homo sapiens (human)
cell leading edge	Protein kinase C zeta type	Homo sapiens (human)
vesicle	Protein kinase C zeta type	Homo sapiens (human)
myelin sheath abaxonal region	Protein kinase C zeta type	Homo sapiens (human)
axon hillock	Protein kinase C zeta type	Homo sapiens (human)
apical cortex	Protein kinase C zeta type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C zeta type	Homo sapiens (human)
extracellular exosome	Protein kinase C zeta type	Homo sapiens (human)
tight junction	Protein kinase C zeta type	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Protein kinase C zeta type	Homo sapiens (human)
glutamatergic synapse	Protein kinase C zeta type	Homo sapiens (human)
PAR polarity complex	Protein kinase C zeta type	Homo sapiens (human)
extracellular region	Protein kinase C delta type	Homo sapiens (human)
nucleus	Protein kinase C delta type	Homo sapiens (human)
nucleoplasm	Protein kinase C delta type	Homo sapiens (human)
cytoplasm	Protein kinase C delta type	Homo sapiens (human)
mitochondrion	Protein kinase C delta type	Homo sapiens (human)
endoplasmic reticulum	Protein kinase C delta type	Homo sapiens (human)
cytosol	Protein kinase C delta type	Homo sapiens (human)
plasma membrane	Protein kinase C delta type	Homo sapiens (human)
cell-cell junction	Protein kinase C delta type	Homo sapiens (human)
nuclear matrix	Protein kinase C delta type	Homo sapiens (human)
azurophil granule lumen	Protein kinase C delta type	Homo sapiens (human)
endolysosome	Protein kinase C delta type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C delta type	Homo sapiens (human)
extracellular exosome	Protein kinase C delta type	Homo sapiens (human)
nucleus	Tyrosine-protein kinase BTK	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase BTK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase BTK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase BTK	Homo sapiens (human)
cytoplasmic vesicle	Tyrosine-protein kinase BTK	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase BTK	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase BTK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase BTK	Homo sapiens (human)
nucleus	Activated CDC42 kinase 1	Homo sapiens (human)
cytoplasm	Activated CDC42 kinase 1	Homo sapiens (human)
endosome	Activated CDC42 kinase 1	Homo sapiens (human)
cytosol	Activated CDC42 kinase 1	Homo sapiens (human)
plasma membrane	Activated CDC42 kinase 1	Homo sapiens (human)
clathrin-coated pit	Activated CDC42 kinase 1	Homo sapiens (human)
adherens junction	Activated CDC42 kinase 1	Homo sapiens (human)
membrane	Activated CDC42 kinase 1	Homo sapiens (human)
clathrin-coated vesicle	Activated CDC42 kinase 1	Homo sapiens (human)
cytoplasmic vesicle membrane	Activated CDC42 kinase 1	Homo sapiens (human)
intracellular membrane-bounded organelle	Activated CDC42 kinase 1	Homo sapiens (human)
perinuclear region of cytoplasm	Activated CDC42 kinase 1	Homo sapiens (human)
cytoophidium	Activated CDC42 kinase 1	Homo sapiens (human)
Grb2-EGFR complex	Activated CDC42 kinase 1	Homo sapiens (human)
plasma membrane	Activated CDC42 kinase 1	Homo sapiens (human)
extracellular space	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
plasma membrane	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
extracellular exosome	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
receptor complex	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
plasma membrane	Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)
plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
cell surface	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
perinuclear region of cytoplasm	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
voltage-gated potassium channel complex	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
inward rectifier potassium channel complex	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
plasma membrane	Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)
Golgi membrane	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
basolateral plasma membrane	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 4	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 4	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase 4	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 4	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 4	Homo sapiens (human)
nuclear body	Serine/threonine-protein kinase 4	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase 4	Homo sapiens (human)
cytoplasm	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nucleoplasm	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cytoplasm	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
cytosol	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
apical plasma membrane	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nuclear speck	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
axon	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
dendrite	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nucleotide-activated protein kinase complex	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
neuronal cell body	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
chromatin	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)
spindle	Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 7	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 7	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 7	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 7	Homo sapiens (human)
PML body	Mitogen-activated protein kinase 7	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 7	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 7	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cell-cell junction	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
postsynaptic density	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
secretory granule	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
glutamatergic synapse	Serine/threonine-protein kinase PAK 2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 3	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase 3	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 3	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase 3	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)
cytosol	Integrin-linked protein kinase	Homo sapiens (human)
plasma membrane	Integrin-linked protein kinase	Homo sapiens (human)
focal adhesion	Integrin-linked protein kinase	Homo sapiens (human)
membrane	Integrin-linked protein kinase	Homo sapiens (human)
sarcomere	Integrin-linked protein kinase	Homo sapiens (human)
lamellipodium	Integrin-linked protein kinase	Homo sapiens (human)
focal adhesion	Integrin-linked protein kinase	Homo sapiens (human)
stress fiber	Integrin-linked protein kinase	Homo sapiens (human)
Golgi membrane	Rho-associated protein kinase 1	Homo sapiens (human)
ruffle	Rho-associated protein kinase 1	Homo sapiens (human)
extracellular region	Rho-associated protein kinase 1	Homo sapiens (human)
centriole	Rho-associated protein kinase 1	Homo sapiens (human)
cytosol	Rho-associated protein kinase 1	Homo sapiens (human)
cytoskeleton	Rho-associated protein kinase 1	Homo sapiens (human)
plasma membrane	Rho-associated protein kinase 1	Homo sapiens (human)
cytoplasmic stress granule	Rho-associated protein kinase 1	Homo sapiens (human)
lamellipodium	Rho-associated protein kinase 1	Homo sapiens (human)
bleb	Rho-associated protein kinase 1	Homo sapiens (human)
secretory granule lumen	Rho-associated protein kinase 1	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Rho-associated protein kinase 1	Homo sapiens (human)
cytoskeleton	Rho-associated protein kinase 1	Homo sapiens (human)
cytoplasm	Rho-associated protein kinase 1	Homo sapiens (human)
cytoplasmic stress granule	Rho-associated protein kinase 1	Homo sapiens (human)
cytoplasm	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
membrane	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
plasma membrane	Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
membrane	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
endocytic vesicle membrane	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
sarcoplasmic reticulum membrane	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
calcium- and calmodulin-dependent protein kinase complex	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
neuron projection	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)
nucleus	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
membrane	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
endocytic vesicle membrane	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
sarcoplasmic reticulum membrane	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
sarcolemma	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
calcium- and calmodulin-dependent protein kinase complex	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
neuron projection	Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)
cytoskeleton	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nucleus	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nucleus	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nucleoplasm	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
cytoplasm	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
nuclear speck	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
axon	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
dendrite	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
ribonucleoprotein complex	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)
cytoplasm	Activin receptor type-2B	Homo sapiens (human)
plasma membrane	Activin receptor type-2B	Homo sapiens (human)
protein-containing complex	Activin receptor type-2B	Homo sapiens (human)
receptor complex	Activin receptor type-2B	Homo sapiens (human)
activin receptor complex	Activin receptor type-2B	Homo sapiens (human)
plasma membrane	Activin receptor type-2B	Homo sapiens (human)
caveola	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
extracellular space	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
nucleoplasm	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
clathrin-coated pit	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
adherens junction	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
basal plasma membrane	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
cell surface	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
postsynaptic density	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
apical plasma membrane	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
axon	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
dendrite	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
neuronal cell body	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
plasma membrane	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
receptor complex	Bone morphogenetic protein receptor type-2	Homo sapiens (human)
ruffle	Protein-tyrosine kinase 6	Homo sapiens (human)
nucleus	Protein-tyrosine kinase 6	Homo sapiens (human)
nucleoplasm	Protein-tyrosine kinase 6	Homo sapiens (human)
cytoplasm	Protein-tyrosine kinase 6	Homo sapiens (human)
cytosol	Protein-tyrosine kinase 6	Homo sapiens (human)
plasma membrane	Protein-tyrosine kinase 6	Homo sapiens (human)
nuclear body	Protein-tyrosine kinase 6	Homo sapiens (human)
plasma membrane	Protein-tyrosine kinase 6	Homo sapiens (human)
acrosomal vesicle	cGMP-dependent protein kinase 1	Homo sapiens (human)
nucleoplasm	cGMP-dependent protein kinase 1	Homo sapiens (human)
cytoplasm	cGMP-dependent protein kinase 1	Homo sapiens (human)
Golgi apparatus	cGMP-dependent protein kinase 1	Homo sapiens (human)
cytosol	cGMP-dependent protein kinase 1	Homo sapiens (human)
plasma membrane	cGMP-dependent protein kinase 1	Homo sapiens (human)
sarcolemma	cGMP-dependent protein kinase 1	Homo sapiens (human)
cyclin K-CDK13 complex	Cyclin-dependent kinase 13	Homo sapiens (human)
extracellular region	Cyclin-dependent kinase 13	Homo sapiens (human)
extracellular space	Cyclin-dependent kinase 13	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 13	Homo sapiens (human)
Golgi apparatus	Cyclin-dependent kinase 13	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 13	Homo sapiens (human)
nuclear speck	Cyclin-dependent kinase 13	Homo sapiens (human)
ficolin-1-rich granule lumen	Cyclin-dependent kinase 13	Homo sapiens (human)
nuclear cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 13	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 13	Homo sapiens (human)
cyclin/CDK positive transcription elongation factor complex	Cyclin-dependent kinase 13	Homo sapiens (human)
cytoplasm	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
nucleus	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
nucleoplasm	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
cytoplasm	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
cytosol	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
PML body	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
mitochondrial membrane	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
serine/threonine protein kinase complex	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)
NMDA selective glutamate receptor complex	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
nucleus	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cytoplasm	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cytosol	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cytoskeleton	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
focal adhesion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cell cortex	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
postsynaptic density	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
lamellipodium	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
dendrite	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
growth cone	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
neuronal cell body	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
cell body	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
perinuclear region of cytoplasm	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
apical dendrite	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
presynapse	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
glutamatergic synapse	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
postsynaptic density, intracellular component	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
dendritic spine	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
focal adhesion	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
plasma membrane	Protein-tyrosine kinase 2-beta	Homo sapiens (human)
plasma membrane	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
cell cortex	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
membrane	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
cytoplasm	Maternal embryonic leucine zipper kinase	Homo sapiens (human)
chromosome, centromeric region	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
kinetochore	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
condensed nuclear chromosome	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nucleus	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nucleoplasm	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
chromosome	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
cytosol	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nuclear matrix	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mitotic cohesin complex	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
meiotic cohesin complex	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
mitotic spindle pole	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
cohesin complex	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
nucleus	Structural maintenance of chromosomes protein 1A	Homo sapiens (human)
chromosome, telomeric region	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
nucleus	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
nucleoplasm	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
cytoplasm	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
centrosome	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
membrane	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
NuRD complex	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
site of DNA damage	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
cerebellar granule cell to Purkinje cell synapse	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
chromatin	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
protein-containing complex	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
RNA polymerase II transcription regulator complex	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
nucleus	Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)
peroxisome	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
peroxisome	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
peroxisomal membrane	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
peroxisomal matrix	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
cytosol	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
membrane	Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 7	Homo sapiens (human)
glutamatergic synapse	Ephrin type-A receptor 7	Homo sapiens (human)
plasma membrane	Ephrin type-A receptor 7	Homo sapiens (human)
dendrite	Ephrin type-A receptor 7	Homo sapiens (human)
Golgi membrane	Delta(24)-sterol reductase	Homo sapiens (human)
nucleus	Delta(24)-sterol reductase	Homo sapiens (human)
endoplasmic reticulum	Delta(24)-sterol reductase	Homo sapiens (human)
endoplasmic reticulum membrane	Delta(24)-sterol reductase	Homo sapiens (human)
membrane	Delta(24)-sterol reductase	Homo sapiens (human)
cytoplasm	Delta(24)-sterol reductase	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
synapse	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)
stress fiber	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cytoplasm	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cytosol	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
plasma membrane	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
actin cytoskeleton	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
lamellipodium	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cleavage furrow	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cleavage furrow	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
stress fiber	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
lamellipodium	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
cytoplasm	Myosin light chain kinase, smooth muscle	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 11	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 11	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 11	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 11	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase STK11	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase STK11	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase STK11	Homo sapiens (human)
membrane	Serine/threonine-protein kinase STK11	Homo sapiens (human)
Z disc	Serine/threonine-protein kinase STK11	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase STK11	Homo sapiens (human)
serine/threonine protein kinase complex	Serine/threonine-protein kinase STK11	Homo sapiens (human)
intracellular protein-containing complex	Serine/threonine-protein kinase STK11	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase STK11	Homo sapiens (human)
cytosol	Coiled-coil domain-containing protein 6	Homo sapiens (human)
cytoskeleton	Coiled-coil domain-containing protein 6	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase N1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase N1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase N1	Homo sapiens (human)
endosome	Serine/threonine-protein kinase N1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase N1	Homo sapiens (human)
midbody	Serine/threonine-protein kinase N1	Homo sapiens (human)
cleavage furrow	Serine/threonine-protein kinase N1	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase N1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase N2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase N2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase N2	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase N2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase N2	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase N2	Homo sapiens (human)
nuclear body	Serine/threonine-protein kinase N2	Homo sapiens (human)
lamellipodium	Serine/threonine-protein kinase N2	Homo sapiens (human)
midbody	Serine/threonine-protein kinase N2	Homo sapiens (human)
cleavage furrow	Serine/threonine-protein kinase N2	Homo sapiens (human)
apical junction complex	Serine/threonine-protein kinase N2	Homo sapiens (human)
intermediate filament cytoskeleton	Serine/threonine-protein kinase N2	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase N2	Homo sapiens (human)
protein-containing complex	Serine/threonine-protein kinase N2	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 14	Homo sapiens (human)
spindle pole	Mitogen-activated protein kinase 14	Homo sapiens (human)
extracellular region	Mitogen-activated protein kinase 14	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 14	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase 14	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 14	Homo sapiens (human)
mitochondrion	Mitogen-activated protein kinase 14	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase 14	Homo sapiens (human)
nuclear speck	Mitogen-activated protein kinase 14	Homo sapiens (human)
secretory granule lumen	Mitogen-activated protein kinase 14	Homo sapiens (human)
glutamatergic synapse	Mitogen-activated protein kinase 14	Homo sapiens (human)
ficolin-1-rich granule lumen	Mitogen-activated protein kinase 14	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 14	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 14	Homo sapiens (human)
fibrillar center	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
extracellular exosome	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
cytoplasm	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
nucleus	Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)
centrosome	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
microtubule	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
membrane	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
centrosome	Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)
plasma membrane	Discoidin domain-containing receptor 2	Homo sapiens (human)
focal adhesion	Discoidin domain-containing receptor 2	Homo sapiens (human)
actin cytoskeleton	Discoidin domain-containing receptor 2	Homo sapiens (human)
apical plasma membrane	Discoidin domain-containing receptor 2	Homo sapiens (human)
receptor complex	Discoidin domain-containing receptor 2	Homo sapiens (human)
plasma membrane	Discoidin domain-containing receptor 2	Homo sapiens (human)
cytosol	AP2-associated protein kinase 1	Homo sapiens (human)
plasma membrane	AP2-associated protein kinase 1	Homo sapiens (human)
clathrin-coated pit	AP2-associated protein kinase 1	Homo sapiens (human)
clathrin-coated vesicle	AP2-associated protein kinase 1	Homo sapiens (human)
cell leading edge	AP2-associated protein kinase 1	Homo sapiens (human)
terminal bouton	AP2-associated protein kinase 1	Homo sapiens (human)
intracellular membrane-bounded organelle	AP2-associated protein kinase 1	Homo sapiens (human)
presynapse	AP2-associated protein kinase 1	Homo sapiens (human)
cytoplasm	Myosin light chain kinase 3	Homo sapiens (human)
cytosol	Myosin light chain kinase 3	Homo sapiens (human)
cytoplasm	Myosin light chain kinase 3	Homo sapiens (human)
actin cytoskeleton	Myosin light chain kinase 3	Homo sapiens (human)
extracellular exosome	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
perinuclear region of cytoplasm	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
protein-containing complex	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
plasma membrane	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
cytosol	Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)
endomembrane system	Rab-like protein 3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cell-cell junction	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
lamellipodium	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cell leading edge	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
actomyosin	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
actomyosin	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cytoskeleton	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
cell leading edge	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
centriolar satellite	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
cytoskeleton	Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)
mitochondrion	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
mitochondrial matrix	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
cytoplasm	Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)
phagophore assembly site	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
ciliary tip	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
phagophore assembly site membrane	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
autophagosome	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
phagophore assembly site	Serine/threonine-protein kinase ULK3	Homo sapiens (human)
nucleus	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
mitochondrial inner membrane	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
peroxisome	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
mitochondrial membrane	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
mitochondrion	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
cytoplasm	Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)
endoplasmic reticulum	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
endoplasmic reticulum quality control compartment	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
IRE1-TRAF2-ASK1 complex	Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
mitochondrion	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
actin filament	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
membrane	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
lateral plasma membrane	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
dendrite	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
microtubule bundle	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MARK2	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
mitochondrion	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
cytosol	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
ribonucleoprotein granule	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
mitochondrial nucleoid	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
intracellular anatomical structure	ATP-dependent RNA helicase DHX30	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
microtubule cytoskeleton	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TAO1	Homo sapiens (human)
nucleus	STE20-related kinase adapter protein alpha	Homo sapiens (human)
nucleoplasm	STE20-related kinase adapter protein alpha	Homo sapiens (human)
cytoplasm	STE20-related kinase adapter protein alpha	Homo sapiens (human)
cytosol	STE20-related kinase adapter protein alpha	Homo sapiens (human)
serine/threonine protein kinase complex	STE20-related kinase adapter protein alpha	Homo sapiens (human)
intracellular protein-containing complex	STE20-related kinase adapter protein alpha	Homo sapiens (human)
stress fiber	Myosin-14	Homo sapiens (human)
cytosol	Myosin-14	Homo sapiens (human)
brush border	Myosin-14	Homo sapiens (human)
membrane	Myosin-14	Homo sapiens (human)
growth cone	Myosin-14	Homo sapiens (human)
actomyosin	Myosin-14	Homo sapiens (human)
extracellular exosome	Myosin-14	Homo sapiens (human)
myosin II filament	Myosin-14	Homo sapiens (human)
myosin II complex	Myosin-14	Homo sapiens (human)
cytoplasm	Myosin-14	Homo sapiens (human)
myosin filament	Myosin-14	Homo sapiens (human)
mitochondrion	AarF domain-containing protein kinase 1	Homo sapiens (human)
mitochondrial inner membrane	AarF domain-containing protein kinase 1	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
nucleoplasm	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
cytosol	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
Cajal body	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
membrane	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
nuclear speck	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
U2-type prespliceosome	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DDX42	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)
nucleoplasm	MAP kinase-activated protein kinase 5	Homo sapiens (human)
cytosol	MAP kinase-activated protein kinase 5	Homo sapiens (human)
septin cytoskeleton	MAP kinase-activated protein kinase 5	Homo sapiens (human)
protein-containing complex	MAP kinase-activated protein kinase 5	Homo sapiens (human)
cytoplasm	MAP kinase-activated protein kinase 5	Homo sapiens (human)
nucleus	MAP kinase-activated protein kinase 5	Homo sapiens (human)
cytosol	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
translation release factor complex	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)
mitochondrion	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
membrane	Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)
nucleoplasm	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
autophagosome	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
endoplasmic reticulum	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
cytosol	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
intracellular organelle	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
extracellular exosome	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
plasma membrane	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)
axoneme	Mitogen-activated protein kinase 15	Homo sapiens (human)
extracellular region	Mitogen-activated protein kinase 15	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 15	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 15	Homo sapiens (human)
autophagosome	Mitogen-activated protein kinase 15	Homo sapiens (human)
Golgi apparatus	Mitogen-activated protein kinase 15	Homo sapiens (human)
centriole	Mitogen-activated protein kinase 15	Homo sapiens (human)
cell-cell junction	Mitogen-activated protein kinase 15	Homo sapiens (human)
bicellular tight junction	Mitogen-activated protein kinase 15	Homo sapiens (human)
cytoplasmic vesicle	Mitogen-activated protein kinase 15	Homo sapiens (human)
ciliary basal body	Mitogen-activated protein kinase 15	Homo sapiens (human)
meiotic spindle	Mitogen-activated protein kinase 15	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase 15	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase 15	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Nek9	Homo sapiens (human)
microtubule organizing center	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
spindle pole	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
microtubule	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek7	Homo sapiens (human)
nucleus	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
nucleoplasm	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
cytoplasm	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
mitochondrion	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
cytosol	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
cytoplasmic stress granule	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
membrane	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
cleavage body	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
tRNA-splicing ligase complex	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
ribonucleoprotein complex	ATP-dependent RNA helicase DDX1	Homo sapiens (human)
fibrillar center	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
nucleoplasm	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
cytosol	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
nucleus	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
cytoplasm	Inositol hexakisphosphate kinase 1	Homo sapiens (human)
membrane	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)
kinetochore	Aurora kinase B	Homo sapiens (human)
condensed chromosome, centromeric region	Aurora kinase B	Homo sapiens (human)
nucleus	Aurora kinase B	Homo sapiens (human)
nucleoplasm	Aurora kinase B	Homo sapiens (human)
spindle	Aurora kinase B	Homo sapiens (human)
cytosol	Aurora kinase B	Homo sapiens (human)
chromocenter	Aurora kinase B	Homo sapiens (human)
microtubule cytoskeleton	Aurora kinase B	Homo sapiens (human)
midbody	Aurora kinase B	Homo sapiens (human)
chromosome passenger complex	Aurora kinase B	Homo sapiens (human)
mitotic spindle pole	Aurora kinase B	Homo sapiens (human)
mitotic spindle midzone	Aurora kinase B	Homo sapiens (human)
kinetochore	Aurora kinase B	Homo sapiens (human)
spindle pole centrosome	Aurora kinase B	Homo sapiens (human)
spindle microtubule	Aurora kinase B	Homo sapiens (human)
spindle midzone	Aurora kinase B	Homo sapiens (human)
microtubule organizing center	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cytoplasm	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
centrosome	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule organizing center	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cytosol	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
microtubule cytoskeleton	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
dendrite	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
midbody	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
neuron projection	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
gamma-tubulin complex	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
ciliary basal body	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
cytoplasm	MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)
pericentriolar material	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
centrosome	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
centriolar satellite	Serine/threonine-protein kinase Nek1	Homo sapiens (human)
nucleoplasm	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
cytosol	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
neuron projection	Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)
nucleus	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
nucleoplasm	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
cytoplasm	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
EKC/KEOPS complex	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
cytosol	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
nucleus	EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)
Golgi membrane	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
nucleoplasm	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
nucleolus	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
endoplasmic reticulum	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
endoplasmic reticulum membrane	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
Golgi apparatus	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
cytosol	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
membrane	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
cytoplasm	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
nucleus	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
external side of plasma membrane	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein-containing complex	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
protein kinase complex	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
IRE1-TRAF2-ASK1 complex	Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)
cytosol	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
cytosol	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
nucleus	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
cytoplasm	Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)
nucleus	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nucleoplasm	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nucleolus	Nucleolar GTP-binding protein 1	Homo sapiens (human)
cytoplasm	Nucleolar GTP-binding protein 1	Homo sapiens (human)
cytosol	Nucleolar GTP-binding protein 1	Homo sapiens (human)
membrane	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nuclear membrane	Nucleolar GTP-binding protein 1	Homo sapiens (human)
perinuclear region of cytoplasm	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nucleolus	Nucleolar GTP-binding protein 1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase D2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase D2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase D2	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase D2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D2	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase D2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D2	Homo sapiens (human)
chromosome, telomeric region	RNA cytidine acetyltransferase	Homo sapiens (human)
nucleus	RNA cytidine acetyltransferase	Homo sapiens (human)
nucleoplasm	RNA cytidine acetyltransferase	Homo sapiens (human)
nucleolus	RNA cytidine acetyltransferase	Homo sapiens (human)
membrane	RNA cytidine acetyltransferase	Homo sapiens (human)
midbody	RNA cytidine acetyltransferase	Homo sapiens (human)
telomerase holoenzyme complex	RNA cytidine acetyltransferase	Homo sapiens (human)
small-subunit processome	RNA cytidine acetyltransferase	Homo sapiens (human)
nucleolus	RNA cytidine acetyltransferase	Homo sapiens (human)
endoplasmic reticulum membrane	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase SIK2	Homo sapiens (human)
cytoplasm	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cytosol	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cell leading edge	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
perinuclear region of cytoplasm	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
extracellular exosome	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	STE20-like serine/threonine-protein kinase	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TAO3	Homo sapiens (human)
nucleus	dCTP pyrophosphatase 1	Homo sapiens (human)
nucleoplasm	dCTP pyrophosphatase 1	Homo sapiens (human)
mitochondrion	dCTP pyrophosphatase 1	Homo sapiens (human)
cytosol	dCTP pyrophosphatase 1	Homo sapiens (human)
cytosol	dCTP pyrophosphatase 1	Homo sapiens (human)
nucleus	Dual specificity protein kinase CLK4	Homo sapiens (human)
cytosol	Casein kinase I isoform gamma-1	Homo sapiens (human)
nucleus	Casein kinase I isoform gamma-1	Homo sapiens (human)
plasma membrane	Casein kinase I isoform gamma-1	Homo sapiens (human)
cytoplasm	Casein kinase I isoform gamma-1	Homo sapiens (human)
fibrillar center	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
postsynaptic density	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cell junction	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase PAK 6	Homo sapiens (human)
cytoplasm	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
cytosol	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
phenylalanine-tRNA ligase complex	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
membrane	Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)
mitochondrial matrix	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
mitochondrion	Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)
nuclear speck	BMP-2-inducible protein kinase	Homo sapiens (human)
cytoplasm	BMP-2-inducible protein kinase	Homo sapiens (human)
nucleus	BMP-2-inducible protein kinase	Homo sapiens (human)
extracellular region	Obg-like ATPase 1	Homo sapiens (human)
nucleolus	Obg-like ATPase 1	Homo sapiens (human)
cytoplasm	Obg-like ATPase 1	Homo sapiens (human)
centrosome	Obg-like ATPase 1	Homo sapiens (human)
cytosol	Obg-like ATPase 1	Homo sapiens (human)
membrane	Obg-like ATPase 1	Homo sapiens (human)
platelet alpha granule lumen	Obg-like ATPase 1	Homo sapiens (human)
extracellular exosome	Obg-like ATPase 1	Homo sapiens (human)
cytoplasm	Obg-like ATPase 1	Homo sapiens (human)
nucleus	Midasin	Homo sapiens (human)
nucleoplasm	Midasin	Homo sapiens (human)
nucleolus	Midasin	Homo sapiens (human)
cytosol	Midasin	Homo sapiens (human)
membrane	Midasin	Homo sapiens (human)
intermediate filament cytoskeleton	Midasin	Homo sapiens (human)
nucleus	Midasin	Homo sapiens (human)
preribosome, large subunit precursor	Midasin	Homo sapiens (human)
nucleoplasm	SAFB-like transcription modulator	Homo sapiens (human)
nuclear body	SAFB-like transcription modulator	Homo sapiens (human)
nucleus	SAFB-like transcription modulator	Homo sapiens (human)
cytoplasm	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
cell surface	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
extrinsic component of plasma membrane	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
extracellular space	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
cytosol	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
endosome membrane	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
nucleus	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)
nucleus	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)
cyclin K-CDK12 complex	Cyclin-dependent kinase 12	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 12	Homo sapiens (human)
nuclear speck	Cyclin-dependent kinase 12	Homo sapiens (human)
nuclear cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 12	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 12	Homo sapiens (human)
cyclin/CDK positive transcription elongation factor complex	Cyclin-dependent kinase 12	Homo sapiens (human)
nucleoplasm	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
cytoplasm	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrion	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial inner membrane	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial respirasome	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial respiratory chain complex I	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
mitochondrial membrane	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 26	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 26	Homo sapiens (human)
Golgi-associated vesicle	Serine/threonine-protein kinase 26	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 26	Homo sapiens (human)
vesicle membrane	Serine/threonine-protein kinase 26	Homo sapiens (human)
membrane	Serine/threonine-protein kinase 26	Homo sapiens (human)
apical plasma membrane	Serine/threonine-protein kinase 26	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase 26	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase 26	Homo sapiens (human)
cell periphery	Serine/threonine-protein kinase 26	Homo sapiens (human)
FAR/SIN/STRIPAK complex	Serine/threonine-protein kinase 26	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 26	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 26	Homo sapiens (human)
mitochondrion	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
mitochondrial matrix	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinate-CoA ligase complex (ADP-forming)	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
extracellular exosome	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
mitochondrion	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
succinate-CoA ligase complex	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase NLK	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase NLK	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase NLK	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase NLK	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase NLK	Homo sapiens (human)
extracellular space	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
nucleoplasm	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cytosol	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
nucleotide-activated protein kinase complex	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cytoplasm	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
nucleus	5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
intracellular membrane-bounded organelle	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
serine/threonine protein kinase complex	Serine/threonine-protein kinase TBK1	Homo sapiens (human)
stress fiber	Septin-9	Homo sapiens (human)
cytoplasm	Septin-9	Homo sapiens (human)
microtubule	Septin-9	Homo sapiens (human)
axoneme	Septin-9	Homo sapiens (human)
actin cytoskeleton	Septin-9	Homo sapiens (human)
perinuclear region of cytoplasm	Septin-9	Homo sapiens (human)
non-motile cilium	Septin-9	Homo sapiens (human)
septin complex	Septin-9	Homo sapiens (human)
septin ring	Septin-9	Homo sapiens (human)
microtubule cytoskeleton	Septin-9	Homo sapiens (human)
cell division site	Septin-9	Homo sapiens (human)
fibrillar center	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
nucleolus	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
mitochondrion	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
cytosol	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
cytoplasm	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
nucleoplasm	Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)
nucleus	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
nucleoplasm	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytoplasm	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytosol	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytoskeleton	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
apical plasma membrane	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
recycling endosome	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
extracellular exosome	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
presynapse	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
glutamatergic synapse	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
postsynaptic density, intracellular component	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
cytoplasm	TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)
actin cytoskeleton	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
axon	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cytoplasmic vesicle membrane	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cytoplasmic vesicle	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
neuron projection	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
dendritic growth cone	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
axonal growth cone	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
receptor complex	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase TAO2	Homo sapiens (human)
nucleoplasm	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
nucleolus	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
mitochondrion	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
mitochondrial outer membrane	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
endoplasmic reticulum	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
endoplasmic reticulum membrane	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
plasma membrane	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
membrane	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
endoplasmic reticulum	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
membrane	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
mitochondrion	Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)
plasma membrane	ALK tyrosine kinase receptor	Homo sapiens (human)
plasma membrane	ALK tyrosine kinase receptor	Homo sapiens (human)
extracellular exosome	ALK tyrosine kinase receptor	Homo sapiens (human)
protein-containing complex	ALK tyrosine kinase receptor	Homo sapiens (human)
receptor complex	ALK tyrosine kinase receptor	Homo sapiens (human)
fibrillar center	Serine/threonine-protein kinase ICK	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cilium	Serine/threonine-protein kinase ICK	Homo sapiens (human)
ciliary basal body	Serine/threonine-protein kinase ICK	Homo sapiens (human)
ciliary tip	Serine/threonine-protein kinase ICK	Homo sapiens (human)
ciliary base	Serine/threonine-protein kinase ICK	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase ICK	Homo sapiens (human)
cilium	Serine/threonine-protein kinase ICK	Homo sapiens (human)
nucleus	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
membrane	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
nucleoplasm	RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase SIK3	Homo sapiens (human)
nucleoplasm	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)
exon-exon junction complex	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nucleus	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nucleoplasm	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nuclear speck	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
extracellular exosome	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
mediator complex	Thyroid hormone receptor-associated protein 3	Homo sapiens (human)
nucleoplasm	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
chromosome	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
nucleolus	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
nucleus	Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
cytosol	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
plasma membrane	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)
nucleus	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
nucleus	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
cytosol	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
protein-containing complex	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
cytoplasm	Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cell-cell junction	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
lamellipodium	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cell leading edge	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
actomyosin	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cytoskeleton	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
actomyosin	Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)
nucleus	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
cytoplasm	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
nucleus	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
plasma membrane	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
cytoplasm	Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)
Golgi membrane	Serine/threonine-protein kinase 24	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase 24	Homo sapiens (human)
nucleoplasm	Serine/threonine-protein kinase 24	Homo sapiens (human)
nucleolus	Serine/threonine-protein kinase 24	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 24	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 24	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase 24	Homo sapiens (human)
extracellular exosome	Serine/threonine-protein kinase 24	Homo sapiens (human)
FAR/SIN/STRIPAK complex	Serine/threonine-protein kinase 24	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase 24	Homo sapiens (human)
cytoplasm	Serine/threonine-protein kinase 24	Homo sapiens (human)
cytoplasm	Casein kinase I isoform gamma-3	Homo sapiens (human)
plasma membrane	Casein kinase I isoform gamma-3	Homo sapiens (human)
cytoplasm	Casein kinase I isoform gamma-3	Homo sapiens (human)
nucleus	Casein kinase I isoform gamma-3	Homo sapiens (human)
cytoplasm	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
perinuclear region of cytoplasm	Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (739)

Assay ID	Title	Year	Journal	Article
AID1801713	Competition Binding Assays from Article 10.1021/acschembio.5b01063: \\Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.\\	2016	ACS chemical biology, 05-20, Volume: 11, Issue:5	Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.
AID1802611	In Vitro c-Met and VEGFR-2 Enzyme Assay from Article 10.1016/j.bioorg.2017.04.001: \\Discovery of novel 2-substituted-4-(2-fluorophenoxy) pyridine derivatives possessing pyrazolone and triazole moieties as dual c-Met/VEGFR-2 receptor tyrosine kinase inhibi	2017	Bioorganic chemistry, 06, Volume: 72	Discovery of novel 2-substituted-4-(2-fluorophenoxy) pyridine derivatives possessing pyrazolone and triazole moieties as dual c-Met/VEGFR-2 receptor tyrosine kinase inhibitors.
AID1424996	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425131	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1708314	Inhibition of FLT2 (unknown origin)	2021	European journal of medicinal chemistry, Feb-15, Volume: 212	Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
AID1190092	Inhibition of purified recombinant c-MET (unknown origin) using poly (Glu, Tyr) substrate after 60 mins by ELISA	2015	Bioorganic & medicinal chemistry, Feb-01, Volume: 23, Issue:3	Discovery and SAR study of c-Met kinase inhibitors bearing an 3-amino-benzo[d]isoxazole or 3-aminoindazole scaffold.
AID1424901	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1895682	Inhibition of human recombinant full length c-Met in presence of ATP by alphascreen assay	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1424965	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424503	Antitumor activity in patient with metastatic renal cell carcinoma assessed as progression free survival	2017	European journal of medicinal chemistry, Dec-15, Volume: 142	Recent developments in small molecule therapies for renal cell carcinoma.
AID1424485	Antitumor activity in patient with metastatic renal cell carcinoma assessed as overall survival	2017	European journal of medicinal chemistry, Dec-15, Volume: 142	Recent developments in small molecule therapies for renal cell carcinoma.
AID1425129	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425044	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424936	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1780906	Cytotoxicity against human PC-3 cells assessed as reduction cell viability by MTT assay	2021	European journal of medicinal chemistry, Nov-05, Volume: 223	Structure-guided design and development of novel N-phenylpyrimidin-2-amine derivatives as potential c-Met inhibitors.
AID1608892	Induction of apoptosis in human HeLa cells at 40 nM incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1466333	Inhibition of PDGFRalpha (unknown origin) by HTRF method	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1425208	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424946	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424994	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425030	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424954	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1466331	Inhibition of VEGFR-2 (unknown origin) by HTRF method	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1894554	Inhibition of FLT3 (unknown origin) phosphorylation	2021	Journal of medicinal chemistry, 03-25, Volume: 64, Issue:6	FLT3 Inhibitors in Acute Myeloid Leukemia: Challenges and Recent Developments in Overcoming Resistance.
AID1425095	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1352743	Inhibition of RET (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1424904	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425097	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425153	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1276889	Inhibition of human VEGFR-2 using poly(Glu, Tyr) as substrate by AlphaScreen assay	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1424947	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424940	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425053	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1318739	Inhibition of FLT3 (unknown origin)	2016	Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19	The "Cyclopropyl Fragment" is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules.
AID1425037	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425040	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425015	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424998	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424958	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425134	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425135	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424894	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1368121	Antiproliferative activity against mouse BAF3 cells harboring TRP-MET at 1 uM after 72 hrs by CCK-8 assay relative to control	2017	Bioorganic & medicinal chemistry, 12-15, Volume: 25, Issue:24	Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors.
AID1304950	Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA	2016	Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16	Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2.
AID1608516	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425073	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1588572	Antiproliferative activity against human SW620 cells assessed as effect on cell confluence level at 0.12 to 3.33 ug/ml incubated up to 84 hrs and measured every 1 hr by IncuCyte live-cell imaging assay	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1764213	Antiproliferation activity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	2021	Bioorganic & medicinal chemistry letters, 09-01, Volume: 47	Synthesis and biological evaluation of novel ligustrazine-chalcone derivatives as potential anti-triple negative breast cancer agents.
AID1425176	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1352746	Inhibition of IGF1R (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1698865	Antiproliferative against human A549 cells assessed as reduction in cell viability by MTT assay	2020	Bioorganic & medicinal chemistry letters, 12-01, Volume: 30, Issue:23	Design, synthesis and biological evaluation of novel c-Met/HDAC dual inhibitors.
AID1425063	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425047	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425004	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1548475	Selectivity index, ratio of IC50 for N-terminal His6-tagged recombinant human KDR (790 to end residue) expressed in baculovirus in Sf21 insect cells to IC50 for recombinant N-Terminal GST-tagged human RET V804M mutant (658 to end residues)	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET
AID1487155	Growth inhibition of human H460 cells incubated for 72 hrs by CCK8 assay	2017	Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15	Discovery of a highly potent, selective and novel CDK9 inhibitor as an anticancer drug candidate.
AID1608900	Antitumor activity against human SiHa cells xenografted in NOD/SCID BALB/c mouse assessed as tumor growth inhibition at 40 mg/kg, po administered for 21 days	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1588580	Inhibition of Aurora A (unknown origin) at 2 uM pre-incubated for 10 mins before FAM-labeled peptide substrate addition by mobility shift assay relative to control	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1764211	Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	2021	Bioorganic & medicinal chemistry letters, 09-01, Volume: 47	Synthesis and biological evaluation of novel ligustrazine-chalcone derivatives as potential anti-triple negative breast cancer agents.
AID1698862	Inhibition of HDAC1 (unknown origin)	2020	Bioorganic & medicinal chemistry letters, 12-01, Volume: 30, Issue:23	Design, synthesis and biological evaluation of novel c-Met/HDAC dual inhibitors.
AID1421950	Antiangiogenic activity in HUVEC assessed as inhibition of tube formation on matrigel up to 100 nM after 8 hrs by microscopic method	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1424976	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425160	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424912	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425019	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1895680	Inhibition of human recombinant full length FLT3 in presence of ATP by alphascreen assay	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1424930	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608545	Induction of cell cycle arrest in human HeLa cells assessed as accumulation in G2/M phase at 80 nM incubated for 36 hrs by propidium iodide staining based flow cytometry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1594480	Cytotoxicity against human HT-29 cells assessed as reduction in cell proliferation measured after 72 hrs by MTT assay	2019	Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10	Discovery of thiazolidin-4-one urea analogues as novel multikinase inhibitors that potently inhibit FLT3 and VEGFR2.
AID1500159	Inhibition of recombinant human full length KIT using poly (Glu, Tyr) as substrate by alpha screen assay	2017	European journal of medicinal chemistry, Sep-29, Volume: 138	Structure-based design, synthesis, and evaluation of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel c-Met inhibitors.
AID1425069	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608884	Antiproliferative activity against human MDA-MB-231 cells at 40 nM assessed as reduction in cell viability incubated for 48 hrs by EdU staining based laser scanning confocal microscopy	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425023	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424909	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425021	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1533602	Antiproliferative activity against human HT-29 cells at 3.33 ug/ml after 36 to 72 hrs by phase contrast microscopy	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1425198	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424988	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1588583	Cytotoxicity in human HT-29 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1433599	Cytotoxicity against mouse BA/F3 cells assessed as reduction in cell viability by CellTiter-Glo luminescence assay	2017	European journal of medicinal chemistry, Jan-05, Volume: 125	Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor.
AID1735234	Inhibition of RET M918T mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in AKT activation at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1466330	Inhibition of FLT3 (unknown origin) by HTRF method	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1425158	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1276887	Inhibition of human KIT using poly(Glu, Tyr) as substrate by AlphaScreen assay	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1424995	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608877	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability at 80 nM incubated for 48 hrs by EdU staining based laser scanning confocal microscopy	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425128	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425142	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425051	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735217	Growth inhibition of human NIH3T3 cells incubated for 3 days by MTT assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425027	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425123	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608512	Inhibition of recombinant human VEGFR2 (790 to end residues) using myelin ba as substrate at 1 uM incubated for 40 mins by [gamma-33P]-ATP based radiometric assay relative to control	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425107	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735246	Inhibition of RET in human TT cells assessed as reduction in AKT activation at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1421976	Inhibition of c-MET (unknown origin)	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1424900	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425132	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425209	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425096	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424985	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1500162	Inhibition of recombinant human full length TIE2 using poly (Glu, Tyr) as substrate by alpha screen assay	2017	European journal of medicinal chemistry, Sep-29, Volume: 138	Structure-based design, synthesis, and evaluation of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel c-Met inhibitors.
AID1533575	Induction of apoptosis in human HT-29 cells assessed as late apoptotic cells at 5 ug/mL after 72 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.1%)	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1424942	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425045	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1533601	Antiproliferative activity against human HT-29 cells at 10 ug/ml after 72 hrs by IncuCyte live-cell imaging assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1276891	Inhibition of human FLT3 using poly(Glu, Tyr) as substrate by Luciferase-Coupled Chemiluminescence assay	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1608517	Antiproliferative activity against HUVEC cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1735233	Inhibition of RET M918T mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in ERK activation at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425201	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1742792	Inhibition of cell migration in human LC-2-ad cells assessed as migrated distance at 1 uM measured after 52 hrs by microscopic method (Rvb = 819.01 +/- 65.76 micrometer)	2020	European journal of medicinal chemistry, Nov-15, Volume: 206	Pyrrolo[2,3-d]pyrimidine derivatives as inhibitors of RET: Design, synthesis and biological evaluation.
AID1735240	Inhibition of RET V804M mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in RET phosphorylation at Y1062 residue at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1318737	Inhibition of FLT1 (unknown origin)	2016	Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19	The "Cyclopropyl Fragment" is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules.
AID1424984	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1594491	Antimigratory activity against human HT-29 cells assessed as reduction in cell migration at 3.33 ug/ml measured every hour for 48 hrs by IncuCyte real-time cell imaging analysis	2019	Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10	Discovery of thiazolidin-4-one urea analogues as novel multikinase inhibitors that potently inhibit FLT3 and VEGFR2.
AID1425016	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421977	Inhibition of VEGFR2 (unknown origin)	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1424902	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421941	Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1271663	Inhibition of RET C634W mutant in human TT cells assessed as suppression of ERK phosphorylation at T202/Y204 at 1 to 10 uM after 4 hrs by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425164	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425206	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608539	Induction of cell cycle arrest in human T47D cells assessed as accumulation in G2/M phase at 40 nM incubated for 36 hrs by propidium iodide staining based flow cytometry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1318740	Inhibition of TIE-2 (unknown origin)	2016	Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19	The "Cyclopropyl Fragment" is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules.
AID1425034	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425084	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271671	Cell cycle arrest in human Nthy-ori 3-1 cells assessed as accumulation at G2 phase at 10 uM after 24 hrs by annexinV/PI staining-based flow cytometric analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425089	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424917	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1503818	Antiproliferative activity against human NCI-H727 cells after 48 hrs by MTT assay	2017	ACS medicinal chemistry letters, Oct-12, Volume: 8, Issue:10	Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors.
AID1708312	Inhibition of KIT (unknown origin)	2021	European journal of medicinal chemistry, Feb-15, Volume: 212	Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
AID1608918	Inhibition of VEGFR2 in HUVEC cells assessed as reduction in STAT3 phosphorylation at 40 nM incubated for 48 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1180312	Inhibition of RET (unknown origin)	2014	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15	Design, synthesis and evaluation of highly selective pyridone-based class II MET inhibitors.
AID1829828	Inhibition of wildtype human TRKA using poly (Glu,Tyr) 4:1 as substrate in presence of [gamma-33P]ATP by hotspot kinase assay	2021	European journal of medicinal chemistry, Nov-15, Volume: 224	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization.
AID1312492	Inhibition of CCDC6-RET (unknown origin) expressed in mouse BaF3 cells assessed as inhibition of cell proliferation after 72 hrs by SRB/CCK-8 assay	2016	European journal of medicinal chemistry, Aug-08, Volume: 118	An orally available tyrosine kinase ALK and RET dual inhibitor bearing the tetracyclic benzo[b]carbazolone core.
AID1895679	Inhibition of human recombinant full length VEGFR2 in presence of ATP by alphascreen assay	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1916984	Cytotoxicity against HEK293 cells expressing ABCG2-482-T7 in presence of methotrexate	2022	European journal of medicinal chemistry, Nov-05, Volume: 241	Updated chemical scaffolds of ABCG2 inhibitors and their structure-inhibition relationships for future development.
AID1425155	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735271	Inhibition of recombinant human RET V804L mutant using KKKVSRSGLYRSP as substrate incubated for 15 mins followed by Mg/ATP addition and measured after 40 mins by [gamma-33P]-ATP assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1271676	Cytotoxicity against human TT cells assessed as suppression of anchorage-independent growth at 1 uM for 30 days by soft agar assay	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1510860	Inhibition of VEGFR2 (unknown origin)	2019	European journal of medicinal chemistry, Oct-01, Volume: 179	Evolution in medicinal chemistry of sorafenib derivatives for hepatocellular carcinoma.
AID1916983	Cytotoxicity against HEK293 cells expressing ABCG2-482-R in presence of methotrexate	2022	European journal of medicinal chemistry, Nov-05, Volume: 241	Updated chemical scaffolds of ABCG2 inhibitors and their structure-inhibition relationships for future development.
AID1318736	Inhibition of KIT (unknown origin)	2016	Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19	The "Cyclopropyl Fragment" is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules.
AID1276895	Inhibition of FLT3 (unknown origin) phosphorylation transfected in mouse BAF3 cells incubated for 1 to 3 hrs	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1703965	Inhibition of Ron (unknown origin) at 0.5 uM using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assay	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Identification of novel quinoline analogues bearing thiazolidinones as potent kinase inhibitors for the treatment of colorectal cancer.
AID1608563	Induction of apoptosis in human MDA-MB-231 cells assessed as decrease in Bcl2 expression at 40 nM incubated for 48 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1829826	Selectivity index, ratio of IC50 for inhibition of wildtype TRKA (unknown origin) to IC50 for inhibition of TRKA G667C mutant (unknown origin)	2021	European journal of medicinal chemistry, Nov-15, Volume: 224	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization.
AID1608891	Induction of apoptosis in human SiHa cells at 40 nM incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1271629	Inhibition of human Ret S891A mutant by radiometric assay in presence of [gamma-33P]-ATP	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1578272	Antiproliferative activity against human HT-29 cells at 10 uM incubated for 72 hrs by MTT assay relative to control	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Synthesis and biological evaluation of new MET inhibitors with 1,6-naphthyridinone scaffold.
AID1903397	Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 5 uM measured after 24 hrs by PI/Annexin V staining based flow cytometry assay (Rvb = 4.49%)
AID1425115	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1708310	Inhibition of RET (unknown origin)	2021	European journal of medicinal chemistry, Feb-15, Volume: 212	Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
AID1318734	Inhibition of MET (unknown origin)	2016	Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19	The "Cyclopropyl Fragment" is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules.
AID1424990	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425104	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424991	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424975	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425017	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1276888	Inhibition of human c-Met using poly(Glu, Tyr) as substrate by Luciferase-Coupled Chemiluminescence assay	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1895756	Inhibition of recombinant RET V804L (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform method	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1424967	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1903415	Toxicity in BALB/c nude mouse xenografted with human A549 cells assessed as effect on heart at 20 mg/kg, ip administered every two days for 18 days by H and E staining method
AID1735238	Inhibition of RET V804M mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in AKT activation at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1690518	Antiproliferative activity against human U87MG cells assessed as reduction in cell viability after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Apr-15, Volume: 192	Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate.
AID1425130	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735266	Growth inhibition of mouse BaF3 cells harboring RET V804L mutant incubated for 3 days by MTT assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1780903	Inhibition of c-MET kinase (unknown origin) using poly(Glu:Tyr)(4:1) as substrate by ELISA	2021	European journal of medicinal chemistry, Nov-05, Volume: 223	Structure-guided design and development of novel N-phenylpyrimidin-2-amine derivatives as potential c-Met inhibitors.
AID1425169	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1352742	Inhibition of KDR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1157008	Inhibition of c-Met (unknown origin)	2014	European journal of medicinal chemistry, Aug-18, Volume: 83	Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing pyridazinone moiety as potential antitumor agents.
AID1271662	Inhibition of RET C634W mutant in human TT cells assessed as suppression of AKT phosphorylation at T308/S473 at 1 to 10 uM after 4 hrs by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1500161	Inhibition of recombinant human full length AXL using poly (Glu, Tyr) as substrate by alpha screen assay	2017	European journal of medicinal chemistry, Sep-29, Volume: 138	Structure-based design, synthesis, and evaluation of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel c-Met inhibitors.
AID1735273	Inhibition of recombinant human RET using KKKSPGEYVNIEFG as substrate incubated for 15 mins followed by Mg/ATP addition and measured after 40 mins by [gamma-33P]-ATP assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1276890	Inhibition of human TIE2 using poly(Glu, Tyr) as substrate by [33P]-phosphoryl transfer assay	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1271632	Inhibition of TEL-fused Ret S891A mutant (unknown origin) expressed in mouse BaF3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425110	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1276893	Inhibition of c-Met phosphorylation in human PC3 cells incubated for 1 to 3 hrs	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1352747	Inhibition of Src (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1418439	Antiproliferative activity against human MGHU3 cells after 72 hrs by CellTiter-Glo assay	2018	Bioorganic & medicinal chemistry, 11-01, Volume: 26, Issue:20	Design, synthesis, biological evaluation and cellular imaging of imidazo[4,5-b]pyridine derivatives as potent and selective TAM inhibitors.
AID1433598	Inhibition of RET V804M mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability by CellTiter-Glo luminescence assay	2017	European journal of medicinal chemistry, Jan-05, Volume: 125	Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor.
AID1425145	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1235512	Inhibition of VEGFR-2 (unknown origin)	2015	Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15	Design and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives bearing an imidazolone moiety as c-Met kinase inhibitors.
AID1176846	Inhibition of AXL (unknown origin) at 0.1 uM by ELISA method	2015	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 25, Issue:3	Discovery of potent 1H-imidazo[4,5-b]pyridine-based c-Met kinase inhibitors via mechanism-directed structural optimization.
AID1735218	Growth inhibition of mouse BaF3 cells incubated for 3 days by MTT assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425205	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1903389	Antiproliferative activity against human MCF7 cells expressing c-Met after 48 hrs by MTT assay
AID1424935	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1895683	Inhibition of human recombinant full length AXL in presence of ATP by alphascreen assay	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1425065	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425213	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1533565	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1424950	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1533564	Antiproliferative activity against human A549/CDDP cells after 72 hrs by MTT assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1425148	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425154	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1687564	Antiproliferative activity against human PC-3 cells measured after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Jan-15, Volume: 186	Design, synthesis and biological evaluation of new Axl kinase inhibitors containing 1,3,4-oxadiazole acetamide moiety as novel linker.
AID1425162	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425052	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424962	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424919	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1725713	Cytotoxicity against human HEK293 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	2020	ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
AID1780905	Cytotoxicity against human HepG2 cells assessed as reduction cell viability by MTT assay	2021	European journal of medicinal chemistry, Nov-05, Volume: 223	Structure-guided design and development of novel N-phenylpyrimidin-2-amine derivatives as potential c-Met inhibitors.
AID1743099	Inhibition of MET in human MKN-45 cells assessed as reduction in HGF-mediated autophosphorylation	2020	European journal of medicinal chemistry, Dec-15, Volume: 208	Structure-activity relationship study of novel quinazoline-based 1,6-naphthyridinones as MET inhibitors with potent antitumor efficacy.
AID1157009	Inhibition of VEGFR2 (unknown origin)	2014	European journal of medicinal chemistry, Aug-18, Volume: 83	Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing pyridazinone moiety as potential antitumor agents.
AID1608890	Induction of apoptosis in human T47D cells at 40 nM incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1424934	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1557189	Inhibition of FLT3 (unknown origin) using peptide as substrate preincubated with enzyme for 10 mins followed by substrate addition further incubated for 1 hr by mobility shift assay	2019	Bioorganic & medicinal chemistry letters, 10-01, Volume: 29, Issue:19	Design, synthesis, and biological evaluation of 4-((6,7-dimethoxyquinoline-4-yl)oxy)aniline derivatives as FLT3 inhibitors for the treatment of acute myeloid leukemia.
AID1533574	Induction of apoptosis in human HT-29 cells assessed as early apoptotic cells at 5 ug/mL after 72 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0%)	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1304953	Inhibition of full length recombinant human GST or His-tagged VEGFR2 using poly (Glu, Tyr) as substrate by AlphaScreen assay	2016	Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16	Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2.
AID1425086	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1687565	Inhibition of human N-terminal GST-fused Axl cytoplasmic domain (464 to 885 residues) expressed in baculovirus expression system at 1 uM using CSKtide as substrate measured after 1 hr by mobility shift assay relative to control	2020	European journal of medicinal chemistry, Jan-15, Volume: 186	Design, synthesis and biological evaluation of new Axl kinase inhibitors containing 1,3,4-oxadiazole acetamide moiety as novel linker.
AID1425046	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424929	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1283959	Inhibition of KIF5B/RET (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in cell viability after 48 hrs by Cell titre glo-based luminescence assay	2016	European journal of medicinal chemistry, Apr-13, Volume: 112	The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
AID1484905	Inhibition of AXL (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 1 hr by ELISA	2017	European journal of medicinal chemistry, Jul-28, Volume: 135	The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3β inhibitors for the treatment of ovarian cancer.
AID1708316	Inhibition of TIE2 (unknown origin)	2021	European journal of medicinal chemistry, Feb-15, Volume: 212	Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
AID1895758	Inhibition of recombinant RET M918T (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform method	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1533563	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1425117	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421939	Antiproliferative activity against human EBC1 cells after 72 hrs by MTT assay	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1271626	Inhibition of human Ret G691S mutant by radiometric assay in presence of [gamma-33P]-ATP	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1180311	Inhibition of c-Kit (unknown origin)	2014	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15	Design, synthesis and evaluation of highly selective pyridone-based class II MET inhibitors.
AID1425137	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1304949	Antiproliferative activity against recombinant human VEGF-stimulated HUVEC after 120 hrs by CCK8 assay	2016	Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16	Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2.
AID1703968	Anticancer activity against human HT-29 cells assessed as inhibition of cell proliferation by MTT assay	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Identification of novel quinoline analogues bearing thiazolidinones as potent kinase inhibitors for the treatment of colorectal cancer.
AID1594479	Cytotoxicity against human A549 cells assessed as reduction in cell proliferation measured after 72 hrs by MTT assay	2019	Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10	Discovery of thiazolidin-4-one urea analogues as novel multikinase inhibitors that potently inhibit FLT3 and VEGFR2.
AID1424893	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1704070	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors.
AID1594503	Inhibition of c-MET (unknown origin) using FAM-labelled peptide as substrate measured after 10 mins by mobility shift assay	2019	Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10	Discovery of thiazolidin-4-one urea analogues as novel multikinase inhibitors that potently inhibit FLT3 and VEGFR2.
AID1425003	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425094	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425062	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425146	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424997	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424966	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425076	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425172	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1466326	Inhibition of recombinant c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 45 mins by ELISA	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1425105	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1895678	Inhibition of human recombinant full length RET in presence of ATP by alphascreen assay	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1424986	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1704065	Inhibition of c-MET(unknown origin) using FAM labelled peptide substrate at 100 nM preincubated for 10 mins followed by substrate addition and measured by microplate reader method	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors.
AID1424905	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1548473	Inhibition of recombinant N-Terminal GST-tagged human RET V804M mutant (658 to end residues) incubated for 15 mins followed by substrate addition and measured after 30 mins by TR-FRET assay	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET
AID1424945	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1500158	Inhibition of recombinant human full length VEGFR2 using poly (Glu, Tyr) as substrate by alpha screen assay	2017	European journal of medicinal chemistry, Sep-29, Volume: 138	Structure-based design, synthesis, and evaluation of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel c-Met inhibitors.
AID1425018	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424944	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424920	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1533585	Antimigratory activity against human HT-29 cells at 3.33 ug/mL after 48 to 72 hrs by wound healing assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1424957	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424971	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1903414	Toxicity in BALB/c nude mouse xenografted with human A549 cells assessed as effect on kidney at 20 mg/kg, ip administered every two days for 18 days by H and E staining method
AID1780908	Cytotoxicity against human HCT-116 cells assessed as reduction cell viability by MTT assay	2021	European journal of medicinal chemistry, Nov-05, Volume: 223	Structure-guided design and development of novel N-phenylpyrimidin-2-amine derivatives as potential c-Met inhibitors.
AID1425106	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1905552	Inhibition of human RET kinase using IGF1Rtide as substrate incubated for 40 mins and measured by ADP-Glo assay
AID1425054	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425022	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425170	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735247	Inhibition of RET in human TT cells assessed as reduction in RET phosphorylation at Y905 residue at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1608565	Induction of apoptosis in human SiHa cells assessed as decrease in Bcl2 expression at 40 nM incubated for 48 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425031	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1704862	Inhibition of KIF5B-RET V804M mutant fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation measured after 48 hrs by MTS assay	2020	European journal of medicinal chemistry, Dec-01, Volume: 207	Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.
AID1735236	Inhibition of RET M918T mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in RET phosphorylation at Y1062 residue at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1544719	Inhibition of human recombinant His-tagged cMET expressed in baculovirus expression system reduction in phosphorylation using tyrosine 6 peptide as substrate after 60 mins FRET based Z'-LYTE assay	2019	Bioorganic & medicinal chemistry letters, 07-01, Volume: 29, Issue:13	Structure based designing of triazolopyrimidone-based reversible inhibitors for kinases involved in NSCLC.
AID1368122	Antiproliferative activity against human VEGF-stimulated HUVEC cells at 1 uM after 120 hrs by CCK-8 assay relative to control	2017	Bioorganic & medicinal chemistry, 12-15, Volume: 25, Issue:24	Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors.
AID1421940	Antiproliferative activity against human SNU5 cells after 72 hrs by MTT assay	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1424949	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608542	Induction of cell cycle arrest in human SiHa cells assessed as accumulation in G2/M phase at 80 nM incubated for 36 hrs by propidium iodide staining based flow cytometry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1421965	Solubility of the compound after 1 hr by ultrasonic method	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1548478	Selectivity index, ratio of IC50 for KDR (unknown origin) expressed in BaF3 cells to IC50 for RET V804M mutant (unknown origin) expressed in human BaF3 cells	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET
AID1425168	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425072	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1690520	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Apr-15, Volume: 192	Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate.
AID1425038	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1276897	Inhibition of KIT (unknown origin) phosphorylation transfected in human MDA-MB-231 cells incubated for 1 to 3 hrs	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1421942	Inhibition of VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1424978	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424937	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1487156	Growth inhibition of human H1299 cells incubated for 72 hrs by CCK8 assay	2017	Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15	Discovery of a highly potent, selective and novel CDK9 inhibitor as an anticancer drug candidate.
AID1735231	Antitumor activity against human NIH3T3 cells harboring RET C634Y mutant xenografted in NOD-SCID mouse assessed as tumor growth inhibition at 30 mg/kg, po administered for 18 days and measured on day 18	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1304951	Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA	2016	Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16	Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2.
AID1271622	Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1503817	Antiproliferative activity against human HuH7 cells after 48 hrs by MTT assay	2017	ACS medicinal chemistry letters, Oct-12, Volume: 8, Issue:10	Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors.
AID1533561	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1352744	Inhibition of AXL (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1425197	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421935	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1425050	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608920	Inhibition of VEGFR2 in HUVEC cells assessed as reduction in Src phosphorylation at 40 nM incubated for 48 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425196	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421444	Toxicity in nude mouse xenografted with human SNU5 cells assessed as mortality at 30 mg/kg, po qd for 21 days	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR.
AID1424922	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1756933	Induction of apoptosis in human A549 cells assessed as viable cells at 0.5 uM measured after 48 hrs by Annexin V/PI staining based flowcytometry method (Rvb = 92.67%)	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment.
AID1425039	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1283957	Inhibition of recombinant His-tagged human KDR expressed in insect Sf21 cells preincubated for 15 mins followed by substrate addition measured after 20 mins by HTRF assay	2016	European journal of medicinal chemistry, Apr-13, Volume: 112	The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
AID1424928	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1433609	Induction of apoptosis in human Nthy-ori 3-1 cells assessed as increase in cleaved PARP level at 5 uM after 48 hrs by Western blot method	2017	European journal of medicinal chemistry, Jan-05, Volume: 125	Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor.
AID1608922	Antiangiogenic activity against human SiHa cells xenografted in NOD/SCID BALB/c mouse assessed as reduction in CD31 expression at 40 mg/kg, po measured after 21 days by hematoxylin and eosin staining based immunohistochemistry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1424955	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425043	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271624	Inhibition of RET C634W mutant in human TT cells assessed as cell growth inhibition after 10 days by MTT assay	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1271628	Inhibition of human Ret V804L mutant by radiometric assay in presence of [gamma-33P]-ATP	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425028	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608919	Inhibition of VEGFR2 in HUVEC cells assessed as reduction in Akt phosphorylation at 40 nM incubated for 48 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425081	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608881	Inhibition of colony formation in human HeLa cells at 80 nM incubated for 5 days by crystal violet staining based light microscopy	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1578271	Antiproliferative activity against human NIH-H460 cells at 10 uM incubated for 72 hrs by MTT assay relative to control	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Synthesis and biological evaluation of new MET inhibitors with 1,6-naphthyridinone scaffold.
AID1421937	Antiproliferative activity against human NCI-H460 cells after 72 hrs by MTT assay	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1829827	Selectivity index, ratio of IC50 for inhibition of wildtype TRKA (unknown origin) to IC50 for inhibition of TRKA G595R/G667C double mutant (unknown origin)	2021	European journal of medicinal chemistry, Nov-15, Volume: 224	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization.
AID1424961	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1725712	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	2020	ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
AID1687563	Antiproliferative activity against human HT-29 cells measured after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Jan-15, Volume: 186	Design, synthesis and biological evaluation of new Axl kinase inhibitors containing 1,3,4-oxadiazole acetamide moiety as novel linker.
AID1548474	Selectivity index, ratio of IC50 for GST-tagged human RET expressed in baculovirus to IC50 for recombinant N-Terminal GST-tagged human RET V804M mutant (658 to end residues)	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET
AID1690519	Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell viability after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Apr-15, Volume: 192	Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate.
AID1424981	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1352755	Antiproliferative activity against human A549 cells at 3.33 uM after 72 hrs by Incucyte live-cell imaging analysis	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1608883	Antiproliferative activity against human SiHa cells assessed as reduction in cell viability at 80 nM incubated for 48 hrs by EdU staining based laser scanning confocal microscopy	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1421934	Cytotoxicity against HUVEC after 96 hrs by MTT assay	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1425191	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1698864	Antiproliferative against human MCF-7 cells assessed as reduction in cell viability by MTT assay	2020	Bioorganic & medicinal chemistry letters, 12-01, Volume: 30, Issue:23	Design, synthesis and biological evaluation of novel c-Met/HDAC dual inhibitors.
AID1743100	Inhibition of recombinant VEGFR2 kinase domain (unknown origin)	2020	European journal of medicinal chemistry, Dec-15, Volume: 208	Structure-activity relationship study of novel quinazoline-based 1,6-naphthyridinones as MET inhibitors with potent antitumor efficacy.
AID1424913	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1708308	Inhibition of VEGFR2 (unknown origin)	2021	European journal of medicinal chemistry, Feb-15, Volume: 212	Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
AID1425136	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424973	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1578273	Antiproliferative activity against human MKN45 cells at 10 uM incubated for 72 hrs by MTT assay relative to control	2020	European journal of medicinal chemistry, Jan-01, Volume: 185	Synthesis and biological evaluation of new MET inhibitors with 1,6-naphthyridinone scaffold.
AID1588571	Antiproliferative activity against human SW620 cells assessed as cell confluence level at 10 ug/ml incubated up to 84 hrs and measured every 1 hr by IncuCyte live-cell imaging assay (Rvb = 86.5%)	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1271618	Inhibition of TEL-fused wild type Ret (unknown origin) phosphorylation at Y1062/Y905 expressed in mouse BAF3 cells at 0.01 to 10 uM after 1 hr by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1276896	Inhibition of AXL phosphorylation in human MDA-MB-231 cells incubated for 1 to 3 hrs	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1424963	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1698860	Inhibition of HDAC1 (unknown origin) at 100 nM relative to control	2020	Bioorganic & medicinal chemistry letters, 12-01, Volume: 30, Issue:23	Design, synthesis and biological evaluation of novel c-Met/HDAC dual inhibitors.
AID1425010	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1704068	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors.
AID1424999	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271690	Cell cycle arrest in human TT cells expressing Ret C634W mutant at 1 uM after 48 hrs by annexinV/PI staining-based flow cytometric analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1503816	Antiproliferative activity against human A498 cells after 48 hrs by MTT assay	2017	ACS medicinal chemistry letters, Oct-12, Volume: 8, Issue:10	Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors.
AID1690521	Antiproliferative activity against human MKN-45 cells assessed as reduction in cell viability after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Apr-15, Volume: 192	Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate.
AID1425067	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1557187	Antiproliferative activity against human MV4-11 cells harboring FLT3-ITD assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay	2019	Bioorganic & medicinal chemistry letters, 10-01, Volume: 29, Issue:19	Design, synthesis, and biological evaluation of 4-((6,7-dimethoxyquinoline-4-yl)oxy)aniline derivatives as FLT3 inhibitors for the treatment of acute myeloid leukemia.
AID1698861	Inhibition of c-MET (unknown origin) at 100 nM relative to control	2020	Bioorganic & medicinal chemistry letters, 12-01, Volume: 30, Issue:23	Design, synthesis and biological evaluation of novel c-Met/HDAC dual inhibitors.
AID1608515	Antiproliferative activity against human SiHa cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425111	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425189	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1304947	Antiproliferative activity against mouse BA/F3 cells expressing TPR-Met after 72 hrs by CCK8 assay	2016	Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16	Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2.
AID1424896	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735248	Inhibition of RET in human TT cells assessed as reduction in RET phosphorylation at Y1062 residue at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425126	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425178	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425109	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424953	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425159	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735239	Inhibition of RET V804M mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in RET phosphorylation at Y905 residue at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425124	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421947	Inhibition of VEGFR2 phosphorylation in HUVEC at 54 nM after 2 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1352741	Inhibition of Ron (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1180309	Inhibition of recombinant MET kinase domain (unknown origin)	2014	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15	Design, synthesis and evaluation of highly selective pyridone-based class II MET inhibitors.
AID1500160	Inhibition of recombinant human full length RET using poly (Glu, Tyr) as substrate by alpha screen assay	2017	European journal of medicinal chemistry, Sep-29, Volume: 138	Structure-based design, synthesis, and evaluation of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel c-Met inhibitors.
AID1421949	Inhibition of VEGFR2 in HUVEC assessed as decrease in PI3K phosphorylation at 6 to 54 nM after 2 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1903412	Antitumor activity against human A549 cells xenografted in BALB/c nude mouse assessed as reduction in Ki67 expression at 20 mg/kg, ip administered every two days for 18 days by immunohistochemistry
AID1735272	Inhibition of recombinant human RET V804M mutant using KKKVSRSGLYRSP as substrate incubated for 15 mins followed by Mg/ATP addition and measured after 40 mins by [gamma-33P]-ATP assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1271672	Induction of apoptosis in human Nthy-ori 3-1 cells at 10 uM after 48 hrs by annexinV/PI staining-based flow cytometric analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425177	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271615	Inhibition of wild type TEL-fused RET (unknown origin) expressed in mouse BA/F3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1704863	Cytotoxicity against mouse BaF3 cells assessed as reduction in cell proliferation measured after 48 hrs by MTS assay	2020	European journal of medicinal chemistry, Dec-01, Volume: 207	Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.
AID1425002	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608536	Induction of cell cycle arrest in human MDA-MB-231 cells assessed as accumulation in G2/M phase at 40 nM incubated for 36 hrs by propidium iodide staining based flow cytometry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1608882	Antiproliferative activity against human T47D cells assessed as reduction in cell viability at 40 nM incubated for 48 hrs by EdU staining based laser scanning confocal microscopy	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425056	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425098	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425156	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1352745	Inhibition of EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1425060	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271612	Inhibition of TEL-fused Ret V804M mutant (unknown origin) expressed in mouse BA/F3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425101	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735250	Inhibition of colony formation in human NIH3T3 cells at 0.3 to 1 uM incubated for 10 days by crystal violet assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1735229	Toxicity in NOD-SCID mouse xenografted with human NIH3T3 cells harboring RET C634Y mutant assessed as reduction in body weight at 30 mg/kg, po administered for 18 days and measured on day 18	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425141	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608880	Inhibition of colony formation in human SiHa cells at 80 nM incubated for 5 days by crystal violet staining based light microscopy	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1557186	Antiproliferative activity against human HL60 cells harboring wild type FLT3 assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay	2019	Bioorganic & medicinal chemistry letters, 10-01, Volume: 29, Issue:19	Design, synthesis, and biological evaluation of 4-((6,7-dimethoxyquinoline-4-yl)oxy)aniline derivatives as FLT3 inhibitors for the treatment of acute myeloid leukemia.
AID1424970	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1756934	Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 0.5 uM measured after 48 hrs by Annexin V/PI staining based flowcytometry method (Rvb = 1.17%)	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment.
AID1487153	Growth inhibition of human T47D cells incubated for 72 hrs by CCK8 assay	2017	Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15	Discovery of a highly potent, selective and novel CDK9 inhibitor as an anticancer drug candidate.
AID1487157	Growth inhibition of human A549 cells incubated for 72 hrs by CCK8 assay	2017	Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15	Discovery of a highly potent, selective and novel CDK9 inhibitor as an anticancer drug candidate.
AID1849418	Inhibition of recombinant human full length MET using poly(Glu, Tyr) as substrate by alphascreen assay
AID1533599	Cytotoxicity against human FHC cells after 72 hrs by MTT assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1424980	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424979	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424908	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425042	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1895760	Inhibition of recombinant CCDC6-RET (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform method	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1425211	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1180310	Inhibition of recombinant VEGFR2 kinase domain (unknown origin)	2014	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15	Design, synthesis and evaluation of highly selective pyridone-based class II MET inhibitors.
AID1425122	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1466334	Inhibition of RET (unknown origin) by HTRF method	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1425166	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1510862	Inhibition of VEGFR3 (unknown origin)	2019	European journal of medicinal chemistry, Oct-01, Volume: 179	Evolution in medicinal chemistry of sorafenib derivatives for hepatocellular carcinoma.
AID1466336	Inhibition of c-MET (unknown origin)	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1318738	Inhibition of FLT2 (unknown origin)	2016	Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19	The "Cyclopropyl Fragment" is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules.
AID1425212	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425108	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1588585	Cytotoxicity in human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1725714	Selectivity index, ratio of IC50 for human HEK293 cells to IC50 for human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	2020	ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
AID1424933	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1588581	Inhibition of Aurora B (unknown origin) at 2 uM pre-incubated for 10 mins before FAM-labeled peptide substrate addition by mobility shift assay relative to control	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1433600	Inhibition of RET C634W mutant in human TT cells assessed as reduction in cell viability by CellTiter-Glo luminescence assay	2017	European journal of medicinal chemistry, Jan-05, Volume: 125	Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor.
AID1594490	Antimigratory activity against human HT-29 cells assessed as reduction in cell migration at 3.33 ug/ml measured every hour for 72 hrs by IncuCyte real-time cell imaging analysis	2019	Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10	Discovery of thiazolidin-4-one urea analogues as novel multikinase inhibitors that potently inhibit FLT3 and VEGFR2.
AID1500163	Inhibition of recombinant human full length FLT3 using poly (Glu, Tyr) as substrate by alpha screen assay	2017	European journal of medicinal chemistry, Sep-29, Volume: 138	Structure-based design, synthesis, and evaluation of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel c-Met inhibitors.
AID1425120	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1594488	Antiproliferative activity against human HT-29 cells assessed as increase in dead cell population at 10 ug/ml measured after 66 hrs by IncuCyte live-cell imaging analysis	2019	Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10	Discovery of thiazolidin-4-one urea analogues as novel multikinase inhibitors that potently inhibit FLT3 and VEGFR2.
AID1425187	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421938	Antiproliferative activity against human MKN45 cells after 72 hrs by MTT assay	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1424898	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424960	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735269	Growth inhibition of mouse BaF3 cells over expressing wild type RET incubated for 3 days by MTT assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425008	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1756936	Induction of apoptosis in human A549 cells assessed as necrotic cells at 0.5 uM measured after 48 hrs by Annexin V/PI staining based flowcytometry method (Rvb = 2.01%)	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment.
AID1608894	Induction of apoptosis in human HeLa cells assessed as decrease in Bcl2 expression at 80 nM incubated for 48 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1756926	Cytotoxicity against human L02 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment.
AID1235511	Inhibition of c-Met (unknown origin)	2015	Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15	Design and biological evaluation of novel 4-(2-fluorophenoxy)quinoline derivatives bearing an imidazolone moiety as c-Met kinase inhibitors.
AID1424895	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1704858	Inhibition of KIF5B-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation measured after 48 hrs by MTS assay	2020	European journal of medicinal chemistry, Dec-01, Volume: 207	Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.
AID1425083	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1780907	Cytotoxicity against human CAKI-1 cells assessed as reduction cell viability by MTT assay	2021	European journal of medicinal chemistry, Nov-05, Volume: 223	Structure-guided design and development of novel N-phenylpyrimidin-2-amine derivatives as potential c-Met inhibitors.
AID1425149	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1690504	Inhibition of MET (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addition and measured after 30 to 60 mins by HTRF assay	2020	European journal of medicinal chemistry, Apr-15, Volume: 192	Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate.
AID1318735	Inhibition of RET (unknown origin)	2016	Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19	The "Cyclopropyl Fragment" is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules.
AID1271678	Inhibition of Ret-driven oncogenic transformation of human TT cells at 1 uM by soft agar assay	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425180	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271627	Inhibition of human Ret Y791F mutant by radiometric assay in presence of [gamma-33P]-ATP	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425029	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425151	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1704857	Inhibition of CCDC6-RET fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation measured after 48 hrs by MTS assay	2020	European journal of medicinal chemistry, Dec-01, Volume: 207	Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.
AID1829825	Selectivity index, ratio of IC50 for inhibition of wildtype TRKA (unknown origin) to IC50 for inhibition of TRKA G595R mutant (unknown origin)	2021	European journal of medicinal chemistry, Nov-15, Volume: 224	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization.
AID1425190	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421948	Inhibition of VEGFR2 in HUVEC assessed as decrease in MAPK phosphorylation at 6 to 54 nM after 2 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1368125	Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA	2017	Bioorganic & medicinal chemistry, 12-15, Volume: 25, Issue:24	Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors.
AID1424914	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608878	Inhibition of colony formation in human MDA-MB-231 cells at 40 nM incubated for 5 days by crystal violet staining based light microscopy	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425150	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424923	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424969	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425068	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1780904	Cytotoxicity against human PANC-1 cells assessed as reduction cell viability by MTT assay	2021	European journal of medicinal chemistry, Nov-05, Volume: 223	Structure-guided design and development of novel N-phenylpyrimidin-2-amine derivatives as potential c-Met inhibitors.
AID1533571	Cytotoxicity against human HT-29 cells assessed as increase in dead cells at 10 ug/mL up to 36 hrs by yoyo-1 dye-based fluorescence assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1425070	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608566	Antitumor activity against human SiHa cells xenografted in NOD/SCID BALB/c mouse assessed as reduction in Ki67 expression at 40 mg/kg, po measured after 21 days by hematoxylin and eosin staining based immunohistochemistry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1903387	Antiproliferative activity against human A549 cells expressing c-Met after 48 hrs by MTT assay
AID1735270	Growth inhibition of human TT cells incubated for 10 days by MTT assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425140	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1157002	Inhibition of cell proliferation in mouse NIH-3T3/TPR-Met cells	2014	European journal of medicinal chemistry, Aug-18, Volume: 83	Design, synthesis and structure-activity relationships of novel 4-phenoxyquinoline derivatives containing pyridazinone moiety as potential antitumor agents.
AID1424964	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1647176	Inhibition of c-Met (unknown origin) by caliper mobility shift assay	2020	Bioorganic & medicinal chemistry letters, 01-15, Volume: 30, Issue:2	Discovery of novel pyrrolo[2,3-b]pyridine derivatives bearing 4-oxoquinoline moiety as potential antitumor inhibitor.
AID1487154	Growth inhibition of human MCF7 cells incubated for 72 hrs by CCK8 assay	2017	Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15	Discovery of a highly potent, selective and novel CDK9 inhibitor as an anticancer drug candidate.
AID1895681	Inhibition of human recombinant full length c-Kit in presence of ATP by alphascreen assay	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1735268	Growth inhibition of mouse BaF3 cells harboring RET V804M mutant incubated for 3 days by MTT assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425161	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271657	Inhibition of autophosphorylation of RET C634W mutant at Y1062 in human TT cells at 1 uM after 4 hrs by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1424977	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1533560	Inhibition of c-Met (unknown origin) at 0.05 uM using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assay relative to control	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1425171	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425014	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421933	Inhibition of TPR-tagged met (unknown origin) expressed in mouse BAF3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1424932	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1466332	Inhibition of KIT (unknown origin) by HTRF method	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1283958	Selectivity ratio of IC50 for recombinant His-tagged human KDR expressed in insect Sf21 cells to IC50 for human RET cytoplasmic domain (658 to 1114 residues) expressed in baculovirus system	2016	European journal of medicinal chemistry, Apr-13, Volume: 112	The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
AID1425001	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1433596	Inhibition of RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability by CellTiter-Glo luminescence assay	2017	European journal of medicinal chemistry, Jan-05, Volume: 125	Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor.
AID1368126	Inhibition of recombinant VEGFR2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA	2017	Bioorganic & medicinal chemistry, 12-15, Volume: 25, Issue:24	Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors.
AID1425078	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1690535	Antitumour activity against human U87MG cells xenografted in athymic nude mouse assessed as tumour growth inhibition at 12.5 mg/kg, po for 21 days relative to control	2020	European journal of medicinal chemistry, Apr-15, Volume: 192	Discovery of 1,6-naphthyridinone-based MET kinase inhibitor bearing quinoline moiety as promising antitumor drug candidate.
AID1368124	Antiproliferative activity against human VEGF-stimulated HUVEC after 120 hrs by CCK-8 assay	2017	Bioorganic & medicinal chemistry, 12-15, Volume: 25, Issue:24	Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors.
AID1421446	Toxicity in nude mouse xenografted with human SNU5 cells assessed as body weight at 30 mg/kg, po qd for 21 days (Rvb = 19.6 g)	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR.
AID1424959	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425074	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425163	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1318741	Inhibition of AXL (unknown origin)	2016	Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19	The "Cyclopropyl Fragment" is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules.
AID1425085	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271691	Induction of apoptosis in human TT cells expressing Ret C634W mutant at 1 uM after 96 hrs by annexinV/PI staining-based flow cytometric analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1756935	Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 0.5 uM measured after 48 hrs by Annexin V/PI staining based flowcytometry method (Rvb = 3.53%)	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment.
AID1425179	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425006	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1764212	Antiproliferation activity against human MCF-7 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	2021	Bioorganic & medicinal chemistry letters, 09-01, Volume: 47	Synthesis and biological evaluation of novel ligustrazine-chalcone derivatives as potential anti-triple negative breast cancer agents.
AID1708313	Inhibition of FLT1 (unknown origin)	2021	European journal of medicinal chemistry, Feb-15, Volume: 212	Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
AID1425026	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1756925	Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment.
AID1704066	Inhibition of human C-terminal Flag tagged HDAC1 (1 to 482 residues) expressed in SF9 cells using Ac-peptide substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by microplate reader method	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors.
AID1352740	Inhibition of c-Kit (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1352739	Inhibition of c-Met (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISA	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1425024	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425055	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1588574	Antiproliferative activity against human SW620 cells assessed as effect on cell confluence level at 0.12 to 3.33 ug/ml incubated up to 84 hrs and measured every 1 hr by phase contrast microscopy	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1466327	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1425058	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1433597	Cytotoxicity against human Nthy-ori 3-1 cells assessed as reduction in cell viability by CellTiter-Glo luminescence assay	2017	European journal of medicinal chemistry, Jan-05, Volume: 125	Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor.
AID1425174	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1756923	Cytotoxicity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment.
AID1608921	Inhibition of VEGFR2 in HUVEC cells assessed as reduction in ERK1/2 phosphorylation at 40 nM incubated for 48 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1424948	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425000	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424972	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1533604	Inhibition of c-Met phosphorylation in human HT-29 cells at 5 ug/mL after 72 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1588584	Cytotoxicity in human NCI-H1975 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1425203	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1418440	Antiproliferative activity against human RT112 cells after 72 hrs by CellTiter-Glo assay	2018	Bioorganic & medicinal chemistry, 11-01, Volume: 26, Issue:20	Design, synthesis, biological evaluation and cellular imaging of imidazo[4,5-b]pyridine derivatives as potent and selective TAM inhibitors.
AID1425133	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1764214	Antiproliferation activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	2021	Bioorganic & medicinal chemistry letters, 09-01, Volume: 47	Synthesis and biological evaluation of novel ligustrazine-chalcone derivatives as potential anti-triple negative breast cancer agents.
AID1704067	Inhibition of c-MET(unknown origin) using FAM labelled peptide substrate preincubated for 10 mins followed by substrate addition and measured by microplate reader method	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors.
AID1425157	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425200	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425025	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1703964	Inhibition of c-Met (unknown origin) at 1 uM using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assay relative to control	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Identification of novel quinoline analogues bearing thiazolidinones as potent kinase inhibitors for the treatment of colorectal cancer.
AID1484903	Inhibition of Ret (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 1 hr by ELISA	2017	European journal of medicinal chemistry, Jul-28, Volume: 135	The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3β inhibitors for the treatment of ovarian cancer.
AID1687562	Antiproliferative activity against human A549 cells measured after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Jan-15, Volume: 186	Design, synthesis and biological evaluation of new Axl kinase inhibitors containing 1,3,4-oxadiazole acetamide moiety as novel linker.
AID1424918	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425113	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424931	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271631	Inhibition of TEL-fused Ret V804L mutant (unknown origin) expressed in mouse BaF3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1780915	Inhibition of human ERG	2021	European journal of medicinal chemistry, Nov-05, Volume: 223	Structure-guided design and development of novel N-phenylpyrimidin-2-amine derivatives as potential c-Met inhibitors.
AID1424974	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1466328	Antiproliferative activity against human EBC1 cells after 72 hrs by MTT assay	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1368123	Antiproliferative activity against mouse BAF3 cells harboring TRP-MET after 72 hrs by CCK-8 assay	2017	Bioorganic & medicinal chemistry, 12-15, Volume: 25, Issue:24	Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors.
AID1424892	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735242	Inhibition of RET C634Y mutant (unknown origin) expressed in human NIH-3T3 cells assessed as reduction in AKT activation at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425175	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608519	Antiangiogenic activity against HUVEC cells assessed as reduction in tube formation at 20 to 40 nM incubated for 6 hrs by light microscopy	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425011	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608514	Antiproliferative activity against human T47D cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425080	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1352756	Cytotoxicity against human A549 cells at 10 uM after 72 hrs by Incucyte live-cell imaging analysis	2018	European journal of medicinal chemistry, Feb-25, Volume: 146	Identification of novel N
AID1425088	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1756924	Cytotoxicity against human HeLa cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	2021	European journal of medicinal chemistry, Apr-05, Volume: 215	Design, synthesis and biological evaluation of 7H-pyrrolo[2,3-d]pyrimidine derivatives containing 1,8-naphthyridine-4-one fragment.
AID1271620	Inhibition of autophosphorylation of RET C634W mutant at Y905 in human TT cells at 1 uM after 4 hrs by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425199	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425127	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1500157	Inhibition of recombinant human full length c-MET using poly (Glu, Tyr) as substrate by alpha screen assay	2017	European journal of medicinal chemistry, Sep-29, Volume: 138	Structure-based design, synthesis, and evaluation of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel c-Met inhibitors.
AID1735249	Inhibition of cell migration in human NIH3T3 cells at 0.3 to 1 uM incubated for 24 hrs by wound healing assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1487150	Inhibition of VEGFR2 phosphorylation (unknown origin)	2017	Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15	Discovery of a highly potent, selective and novel CDK9 inhibitor as an anticancer drug candidate.
AID1594484	Antiproliferative activity against human HT-29 cells assessed as reduction in cell proliferation at 0.37 ug/ml after 72 hrs by phase contrast microscopy	2019	Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10	Discovery of thiazolidin-4-one urea analogues as novel multikinase inhibitors that potently inhibit FLT3 and VEGFR2.
AID1903404	Induction of cell cycle arrest in human A549 cells assessed as accumulation at G0/G1 phase at 5 uM measured by flow cytometry (Rvb = 57.68%)
AID1425193	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608876	Antiproliferative activity against HUVEC cells assessed as reduction in cell viability at 40 nM measured upto 72 hrs by CCK8 assay	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1903416	Toxicity in BALB/c nude mouse xenografted with human A549 cells assessed as effect on liver at 20 mg/kg, ip administered every two days for 18 days by H and E staining method
AID1271665	Inhibition of p70S6K in human TT cells assessed as suppression of S6 phosphorylation at Y317 at 1 to 10 uM after 4 hrs by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425147	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735237	Inhibition of RET V804M mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in ERK activation at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425138	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424897	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1725711	Inhibition of c-Met exon 14 deletion mutant (unknown origin) using poly (Glu,Tyr) 4:1 as substrate in presence of ATP by Kinase-Glo Max luminescent assay	2020	ACS medicinal chemistry letters, Nov-12, Volume: 11, Issue:11
AID1503807	Antiangiogenic activity in HUVEC assessed as inhibition of tube like structures formation at 10 pM to 1 uM after 14 hrs by matrigel based inverted microscopy	2017	ACS medicinal chemistry letters, Oct-12, Volume: 8, Issue:10	Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors.
AID1425099	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425165	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425185	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424910	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425007	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1895757	Inhibition of recombinant RET V804M (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform method	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1425079	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1176845	Inhibition of RON (unknown origin) at 0.1 uM by ELISA method	2015	Bioorganic & medicinal chemistry letters, Feb-01, Volume: 25, Issue:3	Discovery of potent 1H-imidazo[4,5-b]pyridine-based c-Met kinase inhibitors via mechanism-directed structural optimization.
AID1608569	Toxicity in NOD/SCID BALB/c mouse xenografted with human SiHa cells assessed as body weight at 40 mg/kg, po administered for 21 days	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1698863	Inhibition of c-MET (unknown origin)	2020	Bioorganic & medicinal chemistry letters, 12-01, Volume: 30, Issue:23	Design, synthesis and biological evaluation of novel c-Met/HDAC dual inhibitors.
AID1276894	Inhibition of VEGFR-2 phosphorylation in HUVEC incubated for 1 to 3 hrs	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1708317	Inhibition of AXL (unknown origin)	2021	European journal of medicinal chemistry, Feb-15, Volume: 212	Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
AID1424952	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1895759	Inhibition of recombinant VEGFR2 (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform method	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1425118	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271661	Inhibition of RET C634W mutant in human TT cells assessed as suppression of PLCgamma phosphorylation at Y783 at 1 to 10 uM after 4 hrs by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425035	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424982	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424891	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425192	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425071	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424907	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1895755	Inhibition of wildtype RET (unknown origin) incubated for 120 mins by Perkin Elmer electrophoretic mobility shift platform method	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1425181	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1703966	Inhibition of c-Met (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assay relative to control	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Identification of novel quinoline analogues bearing thiazolidinones as potent kinase inhibitors for the treatment of colorectal cancer.
AID1849419	Inhibition of recombinant human full length KDR using poly(Glu, Tyr) as substrate by alphascreen assay
AID1608879	Inhibition of colony formation in human T47D cells at 40 nM incubated for 5 days by crystal violet staining based light microscopy	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1424968	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1708315	Inhibition of FLT3 (unknown origin)	2021	European journal of medicinal chemistry, Feb-15, Volume: 212	Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
AID1425009	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1276886	Inhibition of human RET using poly(Glu, Tyr) as substrate by Luciferase-Coupled Chemiluminescence assay	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1425013	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424899	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424925	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1304952	Inhibition of full length recombinant human GST or His-tagged c-Met using poly (Glu, Tyr) as substrate by luciferase coupled chemiluminescence assay	2016	Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16	Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2.
AID1703967	Inhibition of Ron (unknown origin) using FAM-labelled peptide and ATP incubated for 10 mins by mobility shift assay	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Identification of novel quinoline analogues bearing thiazolidinones as potent kinase inhibitors for the treatment of colorectal cancer.
AID1425093	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425064	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421442	Antitumor activity against human SNU5 cells xenografted in nude mouse assessed as delay in tumor tumor growth at 30 mg/kg, po qd for 21 days relative to control	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR.
AID1424941	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735243	Inhibition of RET C634Y mutant (unknown origin) expressed in human NIH-3T3 cells assessed as reduction in RET phosphorylation at Y905 residue at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1895684	Inhibition of human recombinant full length Tie-2 in presence of ATP by alphascreen assay	2021	Journal of medicinal chemistry, 08-26, Volume: 64, Issue:16	Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical Development.
AID1903398	Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 5 uM measured after 24 hrs by PI/Annexin V staining based flow cytometry assay (Rvb = 2.5%)
AID1704861	Inhibition of CCDC6-RET V804M mutant fusion protein (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation measured after 48 hrs by MTS assay	2020	European journal of medicinal chemistry, Dec-01, Volume: 207	Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.
AID1425173	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735235	Inhibition of RET M918T mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in RET phosphorylation at Y905 residue at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1424956	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424915	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271630	Inhibition of human Ret M918T mutant by radiometric assay in presence of [gamma-33P]-ATP	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425121	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1312487	Inhibition of wild type N-terminal GST-tagged recombinant human RET (658 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA	2016	European journal of medicinal chemistry, Aug-08, Volume: 118	An orally available tyrosine kinase ALK and RET dual inhibitor bearing the tetracyclic benzo[b]carbazolone core.
AID1421966	n-Octanol/water partition coefficient, log P of the compound after 30 mins	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1608513	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by CCK8 assay	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1271680	Inhibition of TEL-fused VEGFR2 (unknown origin) expressed in mouse BA/F3 cells assessed as cell growth inhibition	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1466337	Inhibition of VEGFR-2 (unknown origin)	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1425057	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424992	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608889	Induction of apoptosis in human MDA-MB-231 cells at 40 nM incubated for 48 hrs by annexin V FITC and propidium iodide staining based flow cytometry	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1735267	Growth inhibition of mouse BaF3 cells harboring RET M918T mutant incubated for 3 days by MTT assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1548476	Inhibition of RET V804M mutant (unknown origin)expressed in human BaF3 cells assessed as reduction in cell viability incubated for 48 hrs by celltiter glo luminescence cell viability assay	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET
AID1425204	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425188	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1903405	Induction of cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 5 uM measured by flow cytometry (Rvb = 7.98%)
AID1425210	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424890	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425059	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1588582	Cytotoxicity in human SW620 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1424924	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1421936	Antiproliferative activity against human NCI-H292 cells after 72 hrs by MTT assay	2018	European journal of medicinal chemistry, Oct-05, Volume: 158	Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.
AID1903411	Antitumor activity against human A549 cells xenografted in BALB/c nude mouse assessed as tumor growth inhibition at 20 mg/kg, ip administered every two days for 18 days
AID1903406	Induction of cell cycle arrest in human A549 cells assessed as accumulation at S phase at 5 uM measured by flow cytometry (Rvb = 34.34%)
AID1271649	Inhibition of TEL-fused Ret S891A mutant (unknown origin) phosphorylation at Y1062/Y905 expressed in mouse BAF3 cells at 0.01 to 10 uM after 1 hr by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425116	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424889	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425090	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425186	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424993	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1894555	Inhibition of FLT3-ITD-F691L mutant (unknown origin) phosphorylation in mouse BAF3 cells	2021	Journal of medicinal chemistry, 03-25, Volume: 64, Issue:6	FLT3 Inhibitors in Acute Myeloid Leukemia: Challenges and Recent Developments in Overcoming Resistance.
AID1608526	Antiangiogenic activity in Matrigel plug angiogenic BALB/c mouse assessed as reduction in blood vessel formation at 20 mg/kg, sc measured after 10 days by Matrigel plug assay	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1425167	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271654	Inhibition of TEL-fused Ret V804L/M (unknown origin) expressed in mouse BAF3 after 1 hr by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1204917	Inhibition of RET (unknown origin)	2015	Journal of medicinal chemistry, May-14, Volume: 58, Issue:9	Progress in Discovery of KIF5B-RET Kinase Inhibitors for the Treatment of Non-Small-Cell Lung Cancer.
AID1425036	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424911	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425143	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1424921	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425049	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425144	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1548477	Selectivity index, ratio of IC50 for RET (unknown origin) expressed in BaF3 cells to IC50 for RET V804M mutant (unknown origin) expressed in human BaF3 cells	2020	ACS medicinal chemistry letters, Apr-09, Volume: 11, Issue:4	Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET
AID1588573	Antiproliferative activity against human SW620 cells assessed as cell confluence level at 10 ug/ml incubated up to 84 hrs and measured every 1 hr by phase contrast microscopy (Rvb = 86.5%)	2019	Bioorganic & medicinal chemistry, 09-01, Volume: 27, Issue:17	Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors.
AID1743101	Half life in human liver microsomes	2020	European journal of medicinal chemistry, Dec-15, Volume: 208	Structure-activity relationship study of novel quinazoline-based 1,6-naphthyridinones as MET inhibitors with potent antitumor efficacy.
AID1903388	Antiproliferative activity against human HeLa cells expressing c-Met after 48 hrs by MTT assay
AID1283961	Selectivity ratio of IC50 for KDR inhibition (unknown origin) expressed in mouse BA/F3 cells to IC50 for KIF5B/RET inhibition (unknown origin) expressed in mouse BA/F3 cells	2016	European journal of medicinal chemistry, Apr-13, Volume: 112	The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
AID1271614	Cytotoxicity against human Nthy-ori 3-1 cells after 10 days by MTT assay	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1425082	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1743098	Inhibition of recombinant MET kinase domain (unknown origin)	2020	European journal of medicinal chemistry, Dec-15, Volume: 208	Structure-activity relationship study of novel quinazoline-based 1,6-naphthyridinones as MET inhibitors with potent antitumor efficacy.
AID1304948	Lipophilicity, log P of compound by shake flask method	2016	Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16	Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2.
AID1425061	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1533562	Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1312488	Inhibition of N-terminal GST-tagged recombinant human RET V804M mutant (658 residues) expressed in insect Sf21 cells using poly(Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA	2016	European journal of medicinal chemistry, Aug-08, Volume: 118	An orally available tyrosine kinase ALK and RET dual inhibitor bearing the tetracyclic benzo[b]carbazolone core.
AID1735245	Inhibition of RET in human TT cells assessed as reduction in ERK activation at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1425087	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425100	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1271652	Inhibition of TEL-fused Ret S891A mutant (unknown origin) expressed in mouse BAF3 cells assessed as suppression of phosphorylation of PLCgamma at Y783 at 0.01 to 10 uM after 1 hr by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1283956	Inhibition of human RET cytoplasmic domain (658 to 1114 residues) expressed in baculovirus system preincubated for 15 mins followed by substrate addition measured after 20 mins by HTRF assay	2016	European journal of medicinal chemistry, Apr-13, Volume: 112	The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
AID1276892	Inhibition of human AXL using poly(Glu, Tyr) as substrate	2016	European journal of medicinal chemistry, Jan-27, Volume: 108	Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.
AID1903413	Toxicity in BALB/c nude mouse xenografted with human A549 cells assessed as effect on body weight at 20 mg/kg, ip administered every two days for 18 days
AID1708311	Inhibition of MET (unknown origin)	2021	European journal of medicinal chemistry, Feb-15, Volume: 212	Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
AID1424989	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425033	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425020	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1735241	Inhibition of RET C634Y mutant (unknown origin) expressed in human NIH-3T3 cells assessed as reduction in ERK activation at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1533566	Antiproliferative activity against human MCF7/DX cells after 72 hrs by MTT assay	2019	European journal of medicinal chemistry, Feb-01, Volume: 163	Discovery of N
AID1704069	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	2020	European journal of medicinal chemistry, Oct-15, Volume: 204	Discovery of Novel c-Mesenchymal-Epithelia transition factor and histone deacetylase dual inhibitors.
AID1735244	Inhibition of RET C634Y mutant (unknown origin) expressed in human NIH-3T3 cells assessed as reduction in RET phosphorylation at Y1062 residue at > 0.3 uM incubated for 24 hrs by Western blot analysis	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1849417	Inhibition of AXL (unknown origin)
AID1283960	Inhibition of KDR (unknown origin) expressed in mouse BA/F3 cells assessed as reduction in cell viability after 48 hrs by Cell titre glo-based luminescence assay	2016	European journal of medicinal chemistry, Apr-13, Volume: 112	The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
AID1424939	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425125	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608564	Induction of apoptosis in human T47D cells assessed as decrease in Bcl2 expression at 40 nM incubated for 48 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1271653	Inhibition of TEL-fused Ret S891A mutant (unknown origin) expressed in mouse BAF3 cells assessed as suppression of phosphorylation of Shc at Y317 at 0.01 to 10 uM after 1 hr by Western blot analysis	2016	Journal of medicinal chemistry, Jan-14, Volume: 59, Issue:1	A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.
AID1424926	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1608917	Inhibition of VEGFR2 in HUVEC cells assessed as reduction in VEGFR2 phosphorylation at 40 nM incubated for 48 hrs by Western blot analysis	2019	European journal of medicinal chemistry, Nov-01, Volume: 181	Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.
AID1318733	Inhibition of VEGFR2 (unknown origin)	2016	Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19	The "Cyclopropyl Fragment" is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules.
AID1735264	Growth inhibition of human NIH3T3 cells harboring RET C634Y mutant incubated for 3 days by MTT assay	2018	European journal of medicinal chemistry, Jan-01, Volume: 143	Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
AID1424983	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425048	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1466329	Inhibition of EGFR (unknown origin) by HTRF method	2017	Bioorganic & medicinal chemistry, 06-15, Volume: 25, Issue:12	Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
AID1425207	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1425182	Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry	2017	Science (New York, N.Y.), 12-01, Volume: 358, Issue:6367	The target landscape of clinical kinase drugs.
AID1645848	NCATS Kinetic Aqueous Solubility Profiling	2019	Bioorganic & medicinal chemistry, 07-15, Volume: 27, Issue:14	Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
AID1347411	qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary	2020	ACS chemical biology, 07-17, Volume: 15, Issue:7	High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1347160	Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347159	Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1296008	Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening	2020	SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1	Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1346987	P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346986	P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1508591	NCATS Rat Liver Microsome Stability Profiling	2020	Scientific reports, 11-26, Volume: 10, Issue:1	Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
AID1347113	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for LAN-5 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347091	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347109	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for NB1643 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347083	qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen	2020	Antiviral research, 01, Volume: 173	A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347123	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh41 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347127	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Saos-2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347098	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347111	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SK-N-MC cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347154	Primary screen GU AMC qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347106	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347118	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for TC32 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347115	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for NB-EBc1 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347101	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347129	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SK-N-SH cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347116	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for SJ-GBM2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347114	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for DAOY cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347089	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347121	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for control Hh wild type fibroblast cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347100	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347097	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347124	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for RD cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347128	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for OHS-50 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347093	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347105	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347126	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh30 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347108	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347082	qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal	2020	Antiviral research, 01, Volume: 173	A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347104	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347112	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for BT-12 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347095	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347122	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for U-2 OS cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1745845	Primary qHTS for Inhibitors of ATXN expression
AID1347117	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for BT-37 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID686947	qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen	2013	Bioorganic & medicinal chemistry letters, Aug-01, Volume: 23, Issue:15	Identification of potent Yes1 kinase inhibitors using a library screening approach.
AID1347125	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh18 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347107	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347099	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1508630	Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay	2021	Cell reports, 04-27, Volume: 35, Issue:4	A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347110	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for A673 cells)	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347103	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347096	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347092	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347119	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for MG 63 (6-TG R) cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347094	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347102	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347090	qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells	2018	Oncotarget, Jan-12, Volume: 9, Issue:4	Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347086	qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal	2020	Antiviral research, 01, Volume: 173	A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1508612	NCATS Parallel Artificial Membrane Permeability Assay (PAMPA) Profiling	2017	Bioorganic & medicinal chemistry, 02-01, Volume: 25, Issue:3	Highly predictive and interpretable models for PAMPA permeability.
AID1345506	Human kinase insert domain receptor (Type IV RTKs: VEGF (vascular endothelial growth factor) receptor family)	2011	Molecular cancer therapeutics, Dec, Volume: 10, Issue:12	Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth.
AID1345540	Human MET proto-oncogene, receptor tyrosine kinase (Type X RTKs: HGF (hepatocyte growth factor) receptor family)	2011	Molecular cancer therapeutics, Dec, Volume: 10, Issue:12	Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (0.14)	29.6817
2010's	381 (52.84)	24.3611
2020's	339 (47.02)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	127 (17.37%)	5.53%
Reviews	142 (19.43%)	6.00%
Case Studies	65 (8.89%)	4.05%
Observational	1 (0.14%)	0.25%
Other	396 (54.17%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
adenine [no description available]	2.17	1	0	6-aminopurines; purine nucleobase	Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
lactic acid Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed). 2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.	2.41	1	0	2-hydroxy monocarboxylic acid	algal metabolite; Daphnia magna metabolite
niacinamide nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.	12.64	21	5	pyridine alkaloid; pyridinecarboxamide; vitamin B3	anti-inflammatory agent; antioxidant; cofactor; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; Escherichia coli metabolite; geroprotector; human urinary metabolite; metabolite; mouse metabolite; neuroprotective agent; Saccharomyces cerevisiae metabolite; Sir2 inhibitor
urea pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.	2.21	1	0	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
b 844-39 [no description available]	2.15	1	0	diarylmethane
pk 11195 PK-11195 : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine	3.07	4	0	aromatic amide; isoquinolines; monocarboxylic acid amide; monochlorobenzenes	antineoplastic agent
pd 173074 [no description available]	2.08	1	0	aromatic amine; biaryl; dimethoxybenzene; pyridopyrimidine; tertiary amino compound; ureas	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; fibroblast growth factor receptor antagonist
jtv519 [no description available]	2.89	3	0
abt 702 [no description available]	2.08	1	0	bipyridines
alprazolam Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238). alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.	2.89	3	0	organochlorine compound; triazolobenzodiazepine	anticonvulsant; anxiolytic drug; GABA agonist; muscle relaxant; sedative; xenobiotic
dan 2163 [no description available]	2.89	3	0	aromatic amide; aromatic amine; benzamides; pyrrolidines; sulfone	environmental contaminant; second generation antipsychotic; xenobiotic
amlexanox amlexanox: SRA-A antagonist;structure given in first source. amlexanox : A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.	2.89	3	0	monocarboxylic acid; pyridochromene	anti-allergic agent; anti-ulcer drug; non-steroidal anti-inflammatory drug
astemizole Astemizole: Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.. astemizole : A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position.	2.89	3	0	benzimidazoles; piperidines	anti-allergic agent; anticoronaviral agent; H1-receptor antagonist
benzbromarone Benzbromarone: Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.. benzbromarone : 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication.	2.89	3	0	1-benzofurans; aromatic ketone	uricosuric drug
betaxolol [no description available]	2.13	1	0	propanolamine	antihypertensive agent; beta-adrenergic antagonist; sympatholytic agent
bicalutamide bicalutamide: approved for treatment of advanced prostate cancer. N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide : A member of the class of (trifluoromethyl)benzenes that is 4-amino-2-(trifluoromethyl)benzonitrile in which one of the amino hydrogens is substituted by a 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoyl group.. bicalutamide : A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism.	2.08	1	0	(trifluoromethyl)benzenes; monocarboxylic acid amide; monofluorobenzenes; nitrile; sulfone; tertiary alcohol
bisindolylmaleimide i bisindolylmaleimide I: a bis(indolyl)maleimide	2.89	3	0
bufexamac Bufexamac: A benzeneacetamide with anti-inflammatory, analgesic, and antipyretic action. It is administered topically, orally, or rectally.. bufexamac : A hydroxamic acid derived from phenylacetamide in which the benzene moiety is substituted at C-4 by a butoxy group. It has anti-inflammatory, analgesic, and antipyretic properties.	2.89	3	0	aromatic ether; hydroxamic acid	antipyretic; non-narcotic analgesic; non-steroidal anti-inflammatory drug
cadralazine cadralazine: structure given in first source	2.89	3	0	organic molecular entity
verapamil Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.. verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.. 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.	2.08	1	0	aromatic ether; nitrile; polyether; tertiary amino compound
carvedilol [no description available]	2.63	2	0	carbazoles; secondary alcohol; secondary amino compound	alpha-adrenergic antagonist; antihypertensive agent; beta-adrenergic antagonist; cardiovascular drug; vasodilator agent
celecoxib [no description available]	2.08	1	0	organofluorine compound; pyrazoles; sulfonamide; toluenes	cyclooxygenase 2 inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug
cetirizine Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.. cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.	2.63	2	0	ether; monocarboxylic acid; monochlorobenzenes; piperazines	anti-allergic agent; environmental contaminant; H1-receptor antagonist; xenobiotic
chelerythrine chelerythrine : A benzophenanthridine alkaloid isolated from the root of Zanthoxylum simulans, Chelidonium majus L., and other Papaveraceae.	2.08	1	0	benzophenanthridine alkaloid; organic cation	antibacterial agent; antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor
chlorcyclizine chlorcyclizine: was heading 1964-94 (Prov 1964-73); CHLOROCYCLIZINE & HISTACHLORAZINE were see CHLORCYCLIZINE 1977-94; use PIPERAZINES to search CHLORCYCLIZINE 1966-94; histamine H1-blocker used both orally and topically in allergies and also for the prevention of motion sickness	2.89	3	0	diarylmethane
ci 994 tacedinaline: oral cytostatic drug with impressive differential activity against leukemic cells & normal stem-cells. tacedinaline : A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers.	2.89	3	0	acetamides; benzamides; substituted aniline	antineoplastic agent; EC 3.5.1.98 (histone deacetylase) inhibitor
cyclosporine cyclosporin A : A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle.	2.59	2	0
diclofenac Diclofenac: A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.. diclofenac : A monocarboxylic acid consisting of phenylacetic acid having a (2,6-dichlorophenyl)amino group at the 2-position.	7.25	1	0	amino acid; aromatic amine; dichlorobenzene; monocarboxylic acid; secondary amino compound	antipyretic; drug allergen; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic
valproic acid Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.. valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.	8.79	5	4	branched-chain fatty acid; branched-chain saturated fatty acid	anticonvulsant; antimanic drug; EC 3.5.1.98 (histone deacetylase) inhibitor; GABA agent; neuroprotective agent; psychotropic drug; teratogenic agent
ellipticine ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.	7.21	1	0	indole alkaloid; organic heterotetracyclic compound; organonitrogen heterocyclic compound; polycyclic heteroarene	antineoplastic agent; plant metabolite
fenbendazole Fenbendazole: Antinematodal benzimidazole used in veterinary medicine.. fenbendazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.	2.89	3	0	aryl sulfide; benzimidazoles; carbamate ester	antinematodal drug
berotek Fenoterol: A synthetic adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.. fenoterol : A member of the class resorcinols that is 5-(1-hydroxyethyl)benzene-1,3-diol in which one of the methyl hydrogens is replaced by a 1-(4-hydroxyphenyl)propan-2-amino group. A beta2-adrenergic agonist, it is used (as the hydrobromide salt) as a bronchodilator in the management of reversible airway obstruction.	2.15	1	0	resorcinols; secondary alcohol; secondary amino compound	beta-adrenergic agonist; bronchodilator agent; sympathomimetic agent; tocolytic agent
fluorouracil Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.. 5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.	2.69	2	0	nucleobase analogue; organofluorine compound	antimetabolite; antineoplastic agent; environmental contaminant; immunosuppressive agent; radiosensitizing agent; xenobiotic
furosemide Furosemide: A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.. furosemide : A chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.	2.08	1	0	chlorobenzoic acid; furans; sulfonamide	environmental contaminant; loop diuretic; xenobiotic
gabapentin Gabapentin: A cyclohexane-gamma-aminobutyric acid derivative that is used for the treatment of PARTIAL SEIZURES; NEURALGIA; and RESTLESS LEGS SYNDROME.. gabapentin : A gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. Used for treatment of neuropathic pain and restless legs syndrome.	7.25	1	0	gamma-amino acid	anticonvulsant; calcium channel blocker; environmental contaminant; xenobiotic
go 6976 [no description available]	2.89	3	0	indolocarbazole; organic heterohexacyclic compound	EC 2.7.11.13 (protein kinase C) inhibitor
gossypol Gossypol: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.	2.08	1	0
fasudil fasudil: intracellular calcium antagonist; structure in first source. fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.	2.52	2	0	isoquinolines; N-sulfonyldiazepane	antihypertensive agent; calcium channel blocker; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; geroprotector; neuroprotective agent; nootropic agent; vasodilator agent
haloperidol Haloperidol: A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279). haloperidol : A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.	2.89	3	0	aromatic ketone; hydroxypiperidine; monochlorobenzenes; organofluorine compound; tertiary alcohol	antidyskinesia agent; antiemetic; dopaminergic antagonist; first generation antipsychotic; serotonergic antagonist
homochlorocyclizine homochlorocyclizine: RN given refers to parent cpd	2.89	3	0	diarylmethane
hydroxyzine Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.. hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.	2.89	3	0	hydroxyether; monochlorobenzenes; N-alkylpiperazine	anticoronaviral agent; antipruritic drug; anxiolytic drug; dermatologic drug; H1-receptor antagonist
ifenprodil ifenprodil: NMDA receptor antagonist	2.89	3	0	piperidines
indirubin-3'-monoxime indirubin-3'-monoxime: has antiangiogenic activity. indirubin-3'-monoxime : A member of the class of biindoles that is indirubin in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.	2.08	1	0
4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline WHI P131: a quinazoline derivative, inhibitor of glioblastoma cell adhesion and migration	2.54	2	0
1-(2-naphthalenyl)-3-[(phenylmethyl)-propan-2-ylamino]-1-propanone ZM39923: structure in first source	2.89	3	0	naphthalenes
ketamine Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.. ketamine : A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group.	2.89	3	0	cyclohexanones; monochlorobenzenes; secondary amino compound	analgesic; environmental contaminant; intravenous anaesthetic; neurotoxin; NMDA receptor antagonist; xenobiotic
ketoconazole 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.	8.94	2	1	dichlorobenzene; dioxolane; ether; imidazoles; N-acylpiperazine; N-arylpiperazine
ketoprofen Ketoprofen: An IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis.. ketoprofen : An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.	2.89	3	0	benzophenones; oxo monocarboxylic acid	antipyretic; drug allergen; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; non-steroidal anti-inflammatory drug; xenobiotic
leflunomide Leflunomide: An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.. leflunomide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.	2.08	1	0	(trifluoromethyl)benzenes; isoxazoles; monocarboxylic acid amide	antineoplastic agent; antiparasitic agent; EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; hepatotoxic agent; immunosuppressive agent; non-steroidal anti-inflammatory drug; prodrug; pyrimidine synthesis inhibitor; tyrosine kinase inhibitor
letrozole [no description available]	2.08	1	0	nitrile; triazoles	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor
lg 100268 LG 100268: a retinoid X receptor (RXR) selective compound; structure given in first source	2.08	1	0
mebendazole Mebendazole: A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.. mebendazole : A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.	2.89	3	0	aromatic ketone; benzimidazoles; carbamate ester	antinematodal drug; microtubule-destabilising agent; tubulin modulator
mephenesin Mephenesin: A centrally acting muscle relaxant with a short duration of action.. 1-(2-methylphenyl)glycerol : A glycerol ether in which a single 2-methylphenyl group is attached at position 1 of glycerol via an ether linkage.	2.89	3	0	aromatic ether; glycerol ether
metformin Metformin: A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289). metformin : A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.	2.08	1	0	guanidines	environmental contaminant; geroprotector; hypoglycemic agent; xenobiotic
metoprolol Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.. metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.	2.13	1	0	aromatic ether; propanolamine; secondary alcohol; secondary amino compound	antihypertensive agent; beta-adrenergic antagonist; environmental contaminant; geroprotector; xenobiotic
midazolam Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.. midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.	2.11	1	0	imidazobenzodiazepine; monofluorobenzenes; organochlorine compound	anticonvulsant; antineoplastic agent; anxiolytic drug; apoptosis inducer; central nervous system depressant; GABAA receptor agonist; general anaesthetic; muscle relaxant; sedative
mitotane Mitotane: A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.	3.03	1	0	diarylmethane
mitoxantrone Mitoxantrone: An anthracenedione-derived antineoplastic agent.. mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.	10.53	4	1	dihydroxyanthraquinone	analgesic; antineoplastic agent
entinostat [no description available]	2.08	1	0	benzamides; carbamate ester; primary amino compound; pyridines; substituted aniline	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor
niclosamide Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48). niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.	2.89	3	0	benzamides; C-nitro compound; monochlorobenzenes; salicylanilides; secondary carboxamide	anthelminthic drug; anticoronaviral agent; antiparasitic agent; apoptosis inducer; molluscicide; piscicide; STAT3 inhibitor
olprinone olprinone: RN refers to HCl; structure given in first source	2.08	1	0	bipyridines
omeprazole Omeprazole: A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.. omeprazole : A racemate comprising equimolar amounts of (R)- and (S)-omeprazole.. 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.	2.08	1	0	aromatic ether; benzimidazoles; pyridines; sulfoxide
oxibendazole oxibendazole: structure	2.89	3	0	benzimidazoles; carbamate ester
4-(2'-methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine 4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine: a 5-HT(1A) ligand; structure in first source	2.89	3	0
pamidronate [no description available]	2.21	1	0	phosphonoacetic acid
perphenazine Perphenazine: An antipsychotic phenothiazine derivative with actions and uses similar to those of CHLORPROMAZINE.. perphenazine : A phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.	2.89	3	0	N-(2-hydroxyethyl)piperazine; N-alkylpiperazine; organochlorine compound; phenothiazines	antiemetic; dopaminergic antagonist; phenothiazine antipsychotic drug
pimobendan pimobendan: produces arterial & venous dilatation in dogs; structure given in first source	2.89	3	0	benzimidazoles; pyridazinone	cardiotonic drug; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; vasodilator agent
pioglitazone Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.. pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.	2.08	1	0	aromatic ether; pyridines; thiazolidinediones	antidepressant; cardioprotective agent; EC 2.7.1.33 (pantothenate kinase) inhibitor; EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor; ferroptosis inhibitor; geroprotector; hypoglycemic agent; insulin-sensitizing drug; PPARgamma agonist; xenobiotic
ag 1879 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor	2.89	3	0	aromatic amine; monochlorobenzenes; pyrazolopyrimidine	beta-adrenergic antagonist; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; geroprotector
3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1H-indol-2-one [no description available]	2.83	3	0	indoles
riluzole Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.	2.08	1	0	benzothiazoles
ro 31-8220 Ro 31-8220: a protein kinase C inhibitor	2.89	3	0	imidothiocarbamic ester; indoles; maleimides	EC 2.7.11.13 (protein kinase C) inhibitor
ropinirole [no description available]	2.89	3	0	indolones; tertiary amine	antidyskinesia agent; antiparkinson drug; central nervous system drug; dopamine agonist
sb 206553 SB 206553: a high-affinity 5-HT(2C/2B) antagonist; structure given in first source	2.08	1	0	pyrroloindole
sb 220025 SB 220025: inhibits p38 mitogen-activated protein kinase; structure in first source. SB220025 : Am member of the class of imidazoles carrying piperidin-4-yl, 4-fluophenyl and 2-aminopyrimidin-4-yl substituents at posiitons 1, 4 and 5 respectively.	2.08	1	0	aminopyrimidine; imidazoles; organofluorine compound; piperidines	angiogenesis inhibitor; anti-inflammatory agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
sb 202190 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase	2.52	2	0	imidazoles; organofluorine compound; phenols; pyridines	apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
sk&f 86002 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole: inhibits p38 MAP kinase	2.08	1	0	imidazoles
sodium fluoride [no description available]	3.64	1	1	fluoride salt	mutagen
imatinib [no description available]	2.52	2	0	aromatic amine; benzamides; N-methylpiperazine; pyridines; pyrimidines	antineoplastic agent; apoptosis inducer; tyrosine kinase inhibitor
vorinostat Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.. vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).	4.64	7	0	dicarboxylic acid diamide; hydroxamic acid	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor
sulfasalazine Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907). sulfasalazine : An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.	2.08	1	0
2-[4-(1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine [no description available]	2.08	1	0	stilbenoid
temozolomide [no description available]	5.6	4	1	imidazotetrazine; monocarboxylic acid amide; triazene derivative	alkylating agent; antineoplastic agent; prodrug
thalidomide Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.. thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.. 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.	4.72	3	0	phthalimides; piperidones
2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine [no description available]	2.59	2	0	stilbenoid
trifluperidol Trifluperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in the treatment of PSYCHOSES including MANIA and SCHIZOPHRENIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p621)	2.15	1	0	aromatic ketone
troglitazone Troglitazone: A chroman and thiazolidinedione derivative that acts as a PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) agonist. It was formerly used in the treatment of TYPE 2 DIABETES MELLITUS, but has been withdrawn due to hepatotoxicity.	2.08	1	0	chromanes; thiazolidinone	anticoagulant; anticonvulsant; antineoplastic agent; antioxidant; EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor; ferroptosis inhibitor; hypoglycemic agent; platelet aggregation inhibitor; vasodilator agent
whi p180 [no description available]	2.13	1	0
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source. lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.	2.89	3	0	aromatic primary alcohol; furans; indazoles	antineoplastic agent; apoptosis inducer; platelet aggregation inhibitor; soluble guanylate cyclase activator; vasodilator agent
zotepine zotepine: structure	2.89	3	0	dibenzothiepine; tertiary amino compound	alpha-adrenergic drug; second generation antipsychotic; serotonergic drug
prednisone Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.. prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.	7.04	4	4	11-oxo steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(1),Delta(4)-steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	adrenergic agent; anti-inflammatory drug; antineoplastic agent; immunosuppressive agent; prodrug
glutamine Glutamine: A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.. L-glutamine : An optically active form of glutamine having L-configuration.. glutamine : An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4.	3.68	2	0	amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
carbostyril Quinolones: A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.. quinolin-2(1H)-one : A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.	9.59	7	4	monohydroxyquinoline; quinolone	bacterial xenobiotic metabolite
tyrosine Tyrosine: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.. tyrosine : An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring.	5.31	2	1	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; proteinogenic amino acid; tyrosine	EC 1.3.1.43 (arogenate dehydrogenase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
methionine Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.	2.13	1	0	aspartate family amino acid; L-alpha-amino acid; methionine zwitterion; methionine; proteinogenic amino acid	antidote to paracetamol poisoning; human metabolite; micronutrient; mouse metabolite; nutraceutical
colchicine (S)-colchicine : A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions.	2.89	3	0	alkaloid; colchicine	anti-inflammatory agent; gout suppressant; mutagen
benziodarone benziodarone: minor descriptor (75-89); on-line & INDEX MEDICUS search BENZOFURANS (68-89) & IODOBENZOATES (74)	2.89	3	0	aromatic ketone
cytarabine [no description available]	2.61	2	0	beta-D-arabinoside; monosaccharide derivative; pyrimidine nucleoside	antimetabolite; antineoplastic agent; antiviral agent; immunosuppressive agent
threonine Threonine: An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.. threonine : An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 1-hydroxyethyl group.	2.13	1	0	amino acid zwitterion; aspartate family amino acid; L-alpha-amino acid; proteinogenic amino acid; threonine	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
cyclizine Cyclizine: A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935). cyclizine : An N-alkylpiperazine in which one nitrogen of the piperazine ring is substituted by a methyl group, while the other is substituted by a diphenylmethyl group.	2.21	1	0	N-alkylpiperazine	antiemetic; central nervous system depressant; cholinergic antagonist; H1-receptor antagonist; local anaesthetic
methylprednisolone Methylprednisolone: A PREDNISOLONE derivative with similar anti-inflammatory action.. 6alpha-methylprednisolone : The 6alpha-stereoisomer of 6-methylprednisolone.	2.6	1	0	6-methylprednisolone; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone	adrenergic agent; anti-inflammatory drug; antiemetic; environmental contaminant; neuroprotective agent; xenobiotic
trehalose alpha,alpha-trehalose : A trehalose in which both glucose residues have alpha-configuration at the anomeric carbon.	2.89	3	0	trehalose	Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
triclocarban triclocarban: bacteriostat; antiseptic in soaps & other cleansing solns; germicide; structure. triclocarban : A member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively.	2.89	3	0	dichlorobenzene; monochlorobenzenes; phenylureas	antimicrobial agent; antiseptic drug; disinfectant; environmental contaminant; xenobiotic
pyrroles 1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.	14.03	28	9	pyrrole; secondary amine
4-tert-octylphenol 4-tert-octylphenol: structure given in first source	2.89	3	0	alkylbenzene
quinazolines Quinazolines: A group of aromatic heterocyclic compounds that contain a bicyclic structure with two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring.. quinazoline : A mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms.. quinazolines : Any organic heterobicyclic compound based on a quinazoline skeleton and its substituted derivatives.	9.97	37	1	azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; quinazolines
indazoles Indazoles: A group of heterocyclic aromatic organic compounds consisting of the fusion of BENZENE and PYRAZOLES.	9.85	34	1	indazole
benzoxazoles 1,3-benzoxazole : A benzoxazole in which the benzene ring is fused to a 1,3-oxazole ring across positions 4 and 5.. benzoxazole : Compounds based on a fused 1,2- or 1,3-oxazole and benzene bicyclic ring skeleton.	2.72	2	0	1,3-benzoxazoles; mancude organic heterobicyclic parent
thiazoles [no description available]	6.52	5	0	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
pyrazines Pyrazines: A heterocyclic aromatic organic compound with the chemical formula C4H4N2.. pyrazine : A diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms.	6.97	4	1	diazine; pyrazines	Daphnia magna metabolite
ethamivan ethamivan: minor descriptor (65-72); major descriptor (73-86); on-line search BENZAMIDES (66-86); INDEX MEDICUS search BENZAMIDES (65-72); ETHAMIVAN (73-86). etamivan : Phenol substituted at C-2 and C-4 by a methoxy group and an N,N-diethylaminocarbonyl group respectively. A respiratory stimulant drug related to nikethamide, it has now fallen largely into disuse.	2.89	3	0	methoxybenzenes; phenols
azacitidine Azacitidine: A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.. 5-azacytidine : An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia.	2.08	1	0	N-glycosyl-1,3,5-triazine; nucleoside analogue	antineoplastic agent
methysergide Methysergide: An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.. methysergide : A synthetic ergot alkaloid, structurally related to the oxytocic agent methylergonovine and to the potent hallucinogen LSD and used prophylactically to reduce the frequency and intensity of severe vascular headaches.	2.89	3	0	ergoline alkaloid
emetine Emetine: The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.. emetine : A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties.	2.89	3	0	isoquinoline alkaloid; pyridoisoquinoline	antiamoebic agent; anticoronaviral agent; antiinfective agent; antimalarial; antineoplastic agent; antiprotozoal drug; antiviral agent; autophagy inhibitor; emetic; expectorant; plant metabolite; protein synthesis inhibitor
alpha-aminopyridine alpha-aminopyridine: RN given refers to parent cpd; structure in Merck Index, 9th ed, #485. aminopyridine : Compounds containing a pyridine skeleton substituted by one or more amine groups.	4.21	4	0
podophyllotoxin Podophyllum: A genus of poisonous American herbs, family BERBERIDACEAE. The roots yield PODOPHYLLOTOXIN and other pharmacologically important agents. The plant was formerly used as a cholagogue and cathartic. It is different from the European mandrake, MANDRAGORA.	3.07	4	0	furonaphthodioxole; lignan; organic heterotetracyclic compound	antimitotic; antineoplastic agent; keratolytic drug; microtubule-destabilising agent; plant metabolite; tubulin modulator
formestane [no description available]	2.08	1	0	17-oxo steroid; 3-oxo-Delta(4) steroid; enol; hydroxy steroid	antineoplastic agent; EC 1.14.14.14 (aromatase) inhibitor
2-piperidone 2-piperidone: structure given in first source. piperidin-2-one : A delta-lactam that is piperidine which is substituted by an oxo group at position 2.	2.17	1	0	delta-lactam; piperidones	EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor
hydroxychloroquine sulfate [no description available]	2.08	1	0
ethylnitrosourea Ethylnitrosourea: A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.. N-ethyl-N-nitrosourea : A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.	2.15	1	0	N-nitrosoureas	alkylating agent; carcinogenic agent; genotoxin; mutagen
etonitazene etonitazene: was heading 1979-94 (see under BENZIMIDAZOLES 1979-90); ETONITAZIN was see ETONITAZENE 1979-94; use BENZIMIDAZOLES to search ETONITAZENE 1979-94; narcotic analgesic similar to morphine in action; used mainly to study narcotic habituation, tolerance, and withdrawal in laboratory animals	2.89	3	0
deoxycytidine [no description available]	5.08	3	1	pyrimidine 2'-deoxyribonucleoside	Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
tetramethylpyrazine tetramethylpyrazine: found in Ligusticum chuanxiong. tetramethylpyrazine : A member of the class of pyrazines that is pyrazine in which all four hydrogens have been replaced by methyl groups. An alkaloid extracted from Chuanxiong (Ligusticum wallichii).	2.31	1	0	alkaloid; pyrazines	antineoplastic agent; apoptosis inhibitor; bacterial metabolite; neuroprotective agent; platelet aggregation inhibitor; vasodilator agent
sodium hydroxide Sodium Hydroxide: A highly caustic substance that is used to neutralize acids and make sodium salts. (From Merck Index, 11th ed)	2.25	1	0	alkali metal hydroxide
amiloride hydrochloride, anhydrous amiloride hydrochloride : A hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid.	2.08	1	0	hydrochloride	diuretic; sodium channel blocker
clothiapine clothiapine: was heading 1975-94 (was see under DIBENZOTHIAZEPINES 1975-90); CLOTIAPINE was see CLOTHIAPINE 1978-94; use DIBENZOTHIAZEPINES to search CLOTHIAPINE 1975-94; antipsychotic similar to clozapine	2.89	3	0	dibenzothiazepine
benperidol Benperidol: A butyrophenone with general properties similar to those of HALOPERIDOL. It has been used in the treatment of aberrant sexual behavior. (From Martindale, The Extra Pharmacopoeia, 30th ed, p567)	2.89	3	0	aromatic ketone
7-hydroxychlorpromazine 7-hydroxychlorpromazine: RN given refers to parent cpd	2.89	3	0	phenothiazines
acadesine [no description available]	2.08	1	0	1-ribosylimidazolecarboxamide; aminoimidazole; nucleoside analogue	antineoplastic agent; platelet aggregation inhibitor
cladribine [no description available]	2.08	1	0	organochlorine compound; purine 2'-deoxyribonucleoside	antineoplastic agent; immunosuppressive agent
maleic hydrazide Maleic Hydrazide: 1,2-Dihydro-3,6-pyridazinedione. A herbicide and plant growth regulator; also used to control suckering of tobacco. Its residue in food and tobacco is highly toxic, causing CNS disturbances and liver damage.	2.1	1	0	pyridazinone
platinum Platinum: A heavy, soft, whitish metal, resembling tin, with atomic number 78, atomic weight 195.084, symbol Pt. It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as alutiae.	4.99	2	1	elemental platinum; nickel group element atom; platinum group metal atom
camptothecin NSC 100880: carboxylate (opened lactone) form of camptothecin; RN refers to (S)-isomer; structure given in first source	2.89	3	0	delta-lactone; pyranoindolizinoquinoline; quinoline alkaloid; tertiary alcohol	antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor; genotoxin; plant metabolite
thenalidine thenalidine: antihistaminic, antipruritic; RN in Chemline for thenalidine calcium: 67250-62-8; structure	2.89	3	0	dialkylarylamine; tertiary amino compound
fluorides [no description available]	3.64	1	1	halide anion; monoatomic fluorine
daunorubicin Daunorubicin: A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.. anthracycline : Anthracyclines are polyketides that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.. daunorubicin : A natural product found in Actinomadura roseola.	2.21	1	0	aminoglycoside antibiotic; anthracycline; p-quinones; tetracenequinones	antineoplastic agent; bacterial metabolite
bromocriptine Bromocriptine: A semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion.	2.89	3	0	indole alkaloid	antidyskinesia agent; antiparkinson drug; dopamine agonist; hormone antagonist
dexchlorpheniramine dexchlorpheniramine: RN given refers to parent cpd(S)-isomer	2.89	3	0	chlorphenamine
dv 1006 [no description available]	2.89	3	0
zidovudine Zidovudine: A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.. zidovudine : A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase.	2.08	1	0	azide; pyrimidine 2',3'-dideoxyribonucleoside	antimetabolite; antiviral drug; HIV-1 reverse transcriptase inhibitor
paclitaxel Taxus: Genus of coniferous yew trees or shrubs, several species of which have medicinal uses. Notable is the Pacific yew, Taxus brevifolia, which is used to make the anti-neoplastic drug taxol (PACLITAXEL).	9.88	2	1	taxane diterpenoid; tetracyclic diterpenoid	antineoplastic agent; human metabolite; metabolite; microtubule-stabilising agent
climbazole 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one : A ketone that is butan-2-one substituted by a 4-chlorophenoxy and a 1H-imidazol-1-yl group at position 1 and 2 methyl groups at position 3.	2.89	3	0	aromatic ether; hemiaminal ether; imidazoles; ketone; monochlorobenzenes
lonidamine lonidamine: structure. lonidamine : A member of the class of indazoles that is 1H-indazole that is substituted at positions 1 and 3 by 2,4-dichlorobenzyl and carboxy groups, respectively.	2.08	1	0	dichlorobenzene; indazoles; monocarboxylic acid	antineoplastic agent; antispermatogenic agent; EC 2.7.1.1 (hexokinase) inhibitor; geroprotector
triadimenol triadimenol : A member of the class of triazoles that is 3,3-dimethyl-1-(1,2,4-triazol-1-yl)butane-1,2-diol substituted at position O1 by a 4-chlorophenyl group. A fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts.	2.89	3	0	aromatic ether; conazole fungicide; hemiaminal ether; monochlorobenzenes; secondary alcohol; triazole fungicide	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; xenobiotic metabolite
triciribine phosphate [no description available]	2.15	1	0
staurosporine [no description available]	3.1	4	0	indolocarbazole alkaloid; organic heterooctacyclic compound	apoptosis inducer; bacterial metabolite; EC 2.7.11.13 (protein kinase C) inhibitor; geroprotector
amonafide xanafide: salt formulation of amonafide; DNA-intercalating agent and topoisomerase II inhibitor	2.89	3	0	isoquinolines
flupirtine flupirtine: RN given refers to parent cpd without isomeric designation	2.89	3	0	aminopyridine
chaetochromin chaetochromin: from Chaetomium spp.; RN given refers to chaetochromin A	2.89	3	0
enoximone Enoximone: A selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. It is used in patients with CONGESTIVE HEART FAILURE.	2.89	3	0	aromatic ketone
simvastatin Simvastatin: A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.. simvastatin : A member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug.	2.08	1	0	delta-lactone; fatty acid ester; hexahydronaphthalenes; statin (semi-synthetic)	EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor; EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor; ferroptosis inducer; geroprotector; prodrug
itraconazole Itraconazole: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.. itraconazole : An N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(+-)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis.	2.08	1	0	aromatic ether; conazole antifungal drug; cyclic ketal; dichlorobenzene; dioxolane; N-arylpiperazine; triazole antifungal drug; triazoles	EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor; Hedgehog signaling pathway inhibitor; P450 inhibitor
pravadoline [no description available]	2.08	1	0
zileuton [no description available]	2.08	1	0	1-benzothiophenes; ureas	anti-asthmatic drug; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; ferroptosis inhibitor; leukotriene antagonist; non-steroidal anti-inflammatory drug
niguldipine [no description available]	2.08	1	0	diarylmethane
topotecan Topotecan: An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.. topotecan : A pyranoindolizinoquinoline used as an antineoplastic agent. It is a derivative of camptothecin and works by binding to the topoisomerase I-DNA complex and preventing religation of these 328 single strand breaks.	2.8	3	0	pyranoindolizinoquinoline	antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor
eliprodil 1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol : A member of the class of piperidines that is piperidine substituted by a 2-(4-chlorophenyl)-2-hydroxyethyl group at position 1 and by a 4-fluorobenzyl group at position 4.	2.08	1	0	monochlorobenzenes; monofluorobenzenes; piperidines; secondary alcohol; tertiary amino compound
gemcitabine gemcitabine : A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer.	5.3	4	1	organofluorine compound; pyrimidine 2'-deoxyribonucleoside	antimetabolite; antineoplastic agent; antiviral drug; DNA synthesis inhibitor; EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor; environmental contaminant; immunosuppressive agent; photosensitizing agent; prodrug; radiosensitizing agent; xenobiotic
aripiprazole Aripiprazole: A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.. aripiprazole : An N-arylpiperazine that is piperazine substituted by a 4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl group at position 1 and by a 2,3-dichlorophenyl group at position 4. It is an antipsychotic drug used for the treatment of Schizophrenia, and other mood disorders.	2.89	3	0	aromatic ether; delta-lactam; dichlorobenzene; N-alkylpiperazine; N-arylpiperazine; quinolone	drug metabolite; H1-receptor antagonist; second generation antipsychotic; serotonergic agonist
verapamil hydrochloride verapamil hydrochloride : A racemate comprising equimolar amounts of dexverapamil hydrochloride and (S)-verapamil hydrochloride.	2.08	1	0
efavirenz efavirenz: HIV-1 reverse transcriptase inhibitor. efavirenz : 1,4-Dihydro-2H-3,1-benzoxazin-2-one substituted at the 4 position by cyclopropylethynyl and trifluoromethyl groups (S configuration) and at the 6 position by chlorine. A non-nucleoside reverse transcriptase inhibitor with activity against HIV, it is used with other antiretrovirals for combination therapy of HIV infection.	2.08	1	0	acetylenic compound; benzoxazine; cyclopropanes; organochlorine compound; organofluorine compound	antiviral drug; HIV-1 reverse transcriptase inhibitor
thiazolyl blue thiazolyl blue: RN & II refers to bromide. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide : The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.	2.08	1	0	organic bromide salt	colorimetric reagent; dye
plerixafor plerixafor: a bicyclam derivate, highly potent & selective inhibitor of HIV-1 & HIV-2. plerixafor : An azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.	2.15	1	0	azacycloalkane; azamacrocycle; benzenes; crown amine; secondary amino compound; tertiary amino compound	anti-HIV agent; antineoplastic agent; C-X-C chemokine receptor type 4 antagonist; immunological adjuvant
bendamustine [no description available]	2.08	1	0	benzimidazoles
aloxistatin aloxistatin: a membrane-permeable cysteine protease inhibitor. aloxistatin : An L-leucine derivative that is the amide obtained by formal condensation of the carboxy group of (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid with the amino group of N-(3-methylbutyl)-L-leucinamide.	2.21	1	0	epoxide; ethyl ester; L-leucine derivative; monocarboxylic acid amide	anticoronaviral agent; cathepsin B inhibitor
caroverine caroverine: structure	2.08	1	0	quinoxaline derivative
indocate [no description available]	2.89	3	0
cgs 9343b [no description available]	2.08	1	0	benzimidazoles
telmisartan Telmisartan: A biphenyl compound and benzimidazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION.. telmisartan : A member of the class of benzimidazoles used widely in the treatment of hypertension.	2.08	1	0	benzimidazoles; biphenyls; carboxybiphenyl	angiotensin receptor antagonist; antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; environmental contaminant; xenobiotic
2-methoxyestradiol 2-methoxy-17beta-estradiol : A 17beta-hydroxy steroid, being 17beta-estradiol methoxylated at C-2.	2.51	2	0	17beta-hydroxy steroid; 3-hydroxy steroid	angiogenesis modulating agent; antimitotic; antineoplastic agent; human metabolite; metabolite; mouse metabolite
N(4)-acetylsulfathiazole N(4)-acetylsulfathiazole : A sulfonamide that is benzenesulfonamide substituted by an acetylamino group at position 4 and a 1,3-thiazol-2-yl group at the nitrogen atom. It is a metabolite of sulfathiazole.	2.89	3	0	1,3-thiazoles; acetamides; sulfonamide	marine xenobiotic metabolite
triazoles Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.	2.1	1	0	1,2,3-triazole
cyclizine hydrochloride [no description available]	2.59	2	0
2,3-trimethylene-4-quinazolone 2,3-trimethylene-4-quinazolone: structure in first source	2.89	3	0	quinazolines
zoledronic acid Zoledronic Acid: An imidobisphosphonate inhibitor of BONE RESORPTION that is used for the treatment of malignancy-related HYPERCALCEMIA; OSTEITIS DEFORMANS; and OSTEOPOROSIS.. zoledronic acid : An imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position.	4.13	2	0	1,1-bis(phosphonic acid); imidazoles	bone density conservation agent
1,3-dimethyluric acid 1,3-dimethyluric acid : An oxopurine that is 7,9-dihydro-1H-purine-2,6,8(3H)-trionesubstituted by methyl groups at N-1 and N-3.	2.89	3	0	oxopurine	metabolite
danofloxacin [no description available]	2.89	3	0	quinolines
nitrefazole [no description available]	2.89	3	0	imidazoles
alacepril [no description available]	2.08	1	0	dipeptide; thioacetate ester	EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
ubenimex ubenimex: growth inhibitor	2.08	1	0
methotrimeprazine Methotrimeprazine: A phenothiazine with pharmacological activity similar to that of both CHLORPROMAZINE and PROMETHAZINE. It has the histamine-antagonist properties of the antihistamines together with CENTRAL NERVOUS SYSTEM effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604). methotrimeprazine : A member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively.	2.89	3	0	phenothiazines; tertiary amine	anticoronaviral agent; cholinergic antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; non-narcotic analgesic; phenothiazine antipsychotic drug; serotonergic antagonist
a 75925 A 75925: has HIV antiviral & HIV type 1 protease inhibitory activity	2.13	1	0
honokiol [no description available]	8.16	4	0	biphenyls
picropodophyllin picropodophyllin: isolated from American May apple (Podophyllum); inhibits IGF-I autophosphorylation without interfering with tyrosine kinase activity. picropodophyllotoxin : An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing 3,4,5-trimethoxyphenyl and hydroxy substituents.	2.15	1	0	furonaphthodioxole; lignan; organic heterotetracyclic compound	antineoplastic agent; insulin-like growth factor receptor 1 antagonist; plant metabolite; tyrosine kinase inhibitor
9-methoxyellipticine 9-methoxyellipticine: RN given refers to parent cpd	2.89	3	0
3-aminophenoxazone 3-aminophenoxazone: also inhibits sulfatase; structure	2.89	3	0	phenoxazine
3-deazaneplanocin 3-deazaneplanocin: S-adenosylhomocysteine hydrolase antagonist	2.89	3	0
tryptanthrine tryptanthrine: minor constituent of traditional Chinese medicine qing dai	2.89	3	0	alkaloid antibiotic; organic heterotetracyclic compound; organonitrogen heterocyclic compound
2-chlorodiazepam [no description available]	2.89	3	0
Polycartine B [no description available]	2.89	3	0	phenazines
rosiglitazone [no description available]	8.5	1	1	aminopyridine; thiazolidinediones	EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor; ferroptosis inhibitor; insulin-sensitizing drug
aminoquinuride dihydrochloride [no description available]	2.89	3	0
thioproperazine mesylate [no description available]	2.89	3	0	phenothiazines
n(6)-(delta(2)-isopentenyl)adenine N(6)-dimethylallyladenine : A 6-isopentenylaminopurine in which has the isopentenyl double bond is located between the 2 and 3 positions of the isopentenyl group.	2.89	3	0	6-isopentenylaminopurine	cytokinin
4-methyl-N-(phenylmethyl)benzenesulfonamide [no description available]	2.89	3	0	sulfonamide
zpck ZPCK: alkylates histidine residue at active center of bovine chymotrypsin	2.63	2	0
combretastatin combretastatin: cytotoxic principle from South African tree COMBRETUM caffrum; structure given in first source; acts at COLCHICINE site of TUBULIN	3.17	1	0
sr141716 [no description available]	2.89	3	0	amidopiperidine; carbohydrazide; dichlorobenzene; monochlorobenzenes; pyrazoles	anti-obesity agent; appetite depressant; CB1 receptor antagonist
vinpocetine [no description available]	2.08	1	0
(6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide [no description available]	2.59	2	0	aromatic ketone
deguelin deguelin: a natural product from Mundulea sericea; RN refers to (7aS-cis)-isomer; structure given in first source. deguelin : A rotenone that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted by methoxy groups at positions 9 and 10, and by two methyl groups at position 3 (the 7aS,13aS-stereoisomer). It exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants and reported to exert anti-tumour effects in various cancers.	2.08	1	0	aromatic ether; diether; organic heteropentacyclic compound; rotenones	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; antiviral agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; mitochondrial NADH:ubiquinone reductase inhibitor; plant metabolite
fingolimod fingolimod : An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate.	2.89	3	0	aminodiol; primary amino compound	antineoplastic agent; CB1 receptor antagonist; immunosuppressive agent; prodrug; sphingosine-1-phosphate receptor agonist
triptolide [no description available]	2.08	1	0	diterpenoid; epoxide; gamma-lactam; organic heteroheptacyclic compound	antispermatogenic agent; plant metabolite
tesmilifene [no description available]	2.89	3	0	diarylmethane
ecteinascidin 743 [no description available]	2.41	1	0	acetate ester; azaspiro compound; bridged compound; hemiaminal; isoquinoline alkaloid; lactone; organic heteropolycyclic compound; organic sulfide; oxaspiro compound; polyphenol; tertiary amino compound	alkylating agent; angiogenesis modulating agent; anti-inflammatory agent; antineoplastic agent; marine metabolite
sr 48692 SR 48692: structure in first source; a neurotensin receptor-1 antagonist	2.08	1	0	N-acyl-amino acid
elacridar Elacridar: inhibitor of MDR1 PROTEIN; structure given in first source	3.66	2	0
sr 27897 SR 27897: structure given in first source; a CCK(A) receptor antagonist	2.89	3	0	indolyl carboxylic acid
imatinib mesylate imatinib methanesulfonate : A methanesulfonate (mesylate) salt that is the monomesylate salt of imatinib. Used for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours.	8.6	8	2	methanesulfonate salt	anticoronaviral agent; antineoplastic agent; apoptosis inducer; tyrosine kinase inhibitor
gefitinib [no description available]	9.87	9	0	aromatic ether; monochlorobenzenes; monofluorobenzenes; morpholines; quinazolines; secondary amino compound; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist
n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine N-(N-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine: inhibits calcium-activated neutral protease; see also record for E-64; RN given refers to (2-S-(2alpha,3beta)(R*)-isomer)	2.89	3	0	leucine derivative
bay x 1005 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid: inhibits synthesis of leukotriene B4 and 5-hydroxyeicosatetraenoic acid; inhibits five-lipoxygenase activating protein(FLAP)and leukotriene A4 hydrolase(LTA4H); structure given in first source;	2.08	1	0
norketamine norketamine: metabolite of ketamine; RN given refers to cpd without isomeric designation	2.89	3	0	organochlorine compound
indatraline indatraline: RN given for (trans)-isomer; structure in first source	2.63	2	0	indanes
lestaurtinib [no description available]	2.15	1	0	indolocarbazole
gyki 53655 GYKI 53655: an AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate) receptor antagonist	2.08	1	0
methotrexate [no description available]	2.89	3	0	dicarboxylic acid; monocarboxylic acid amide; pteridines	abortifacient; antimetabolite; antineoplastic agent; antirheumatic drug; dermatologic drug; DNA synthesis inhibitor; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; immunosuppressive agent
salvinorin a salvinorin A: from the herb, Salvia divinorum	2.21	1	0	organic heterotricyclic compound; organooxygen compound	metabolite; oneirogen
4-diethoxyphosphorylmethyl-n-(4-bromo-2-cyanophenyl)benzamide 4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide: increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol	2.89	3	0
n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide: binds with high affinity to glial mitochondrial diazepam binding inhibitor receptors & increases mitochondrial steroidogenesis	2.89	3	0	phenylindole
abiraterone [no description available]	13.78	7	1	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; pyridines	antineoplastic agent; EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor
ml-3000 [no description available]	2.08	1	0
l 741626 3-(4-(4-chlorophenyl-4-hydroxypiperidino)methyl)indole: structure in first source	2.89	3	0	piperidines
cd 437 CD 437: selective for retinoic acid receptors gamma. CD437 : A naphthoic acid that is 6-phenylnaphthylene-2-carboxyic acid in which the phenyl substituent has been substituted at positions 3 and 4 by adamant-1-yl and hydroxy groups, respectively. It acts as a selective agonist of retinoic acid receptor (RAR)gamma and induces cell cycle arrest and apoptosis in various cancer cells.	2.08	1	0	adamantanes; monocarboxylic acid; naphthoic acid; phenols	apoptosis inducer; retinoic acid receptor gamma agonist
docetaxel anhydrous Docetaxel: A semisynthetic analog of PACLITAXEL used in the treatment of locally advanced or metastatic BREAST NEOPLASMS and NON-SMALL CELL LUNG CANCER.. docetaxel anhydrous : A tetracyclic diterpenoid that is paclitaxel with the N-benzyloxycarbonyl group replaced by N-tert-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group.	6.31	5	2	secondary alpha-hydroxy ketone; tetracyclic diterpenoid	antimalarial; antineoplastic agent; photosensitizing agent
perifosine [no description available]	2.52	2	0	ammonium betaine; phospholipid	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
dx 8951 [no description available]	2.89	3	0	pyranoindolizinoquinoline
mk 767 5-((2,4-dioxo-5-thiazolidinyl)methyl)-2-methoxy-N-((4-(trifluoromethyl)phenyl)methyl)benzamide: an antihyperlipidemic agent that also functions as an insulin sensitizer, PPARalpha agonist, and PPARgamma agonist; structure in first source	2.08	1	0
vatalanib [no description available]	2.15	1	0	monochlorobenzenes; phthalazines; pyridines; secondary amino compound	angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; vascular endothelial growth factor receptor antagonist
ruboxistaurin ruboxistaurin: inhibits protein kinase C beta; structure in first source	2.15	1	0
bazedoxifene acetate [no description available]	2.08	1	0
canertinib [no description available]	2.52	2	0	monochlorobenzenes; morpholines; organofluorine compound; quinazolines	antineoplastic agent; tyrosine kinase inhibitor
birb 796 [no description available]	2.08	1	0	aromatic ether; morpholines; naphthalenes; pyrazoles; ureas	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; immunomodulator
tipifarnib [no description available]	8.13	8	4	imidazoles; monochlorobenzenes; primary amino compound; quinolone	antineoplastic agent; apoptosis inducer; EC 2.5.1.58 (protein farnesyltransferase) inhibitor
atrasentan Atrasentan: A pyrrolidine and benzodioxole derivative that acts a RECEPTOR, ENDOTHELIN A antagonist. It has therapeutic potential as an antineoplastic agent and for the treatment of DIABETIC NEPHROPATHIES.	5.46	2	0	pyrrolidines
cyc 202 seliciclib : 2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors.	3.25	5	0	2,6-diaminopurines	antiviral drug; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
avasimibe [no description available]	2.89	3	0	monoterpenoid
sb 203580 [no description available]	2.08	1	0	imidazoles; monofluorobenzenes; pyridines; sulfoxide	EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector; Hsp90 inhibitor; neuroprotective agent
enzastaurin [no description available]	2.52	2	0	indoles; maleimides
erlotinib [no description available]	3.4	6	0	aromatic ether; quinazolines; secondary amino compound; terminal acetylenic compound	antineoplastic agent; epidermal growth factor receptor antagonist; protein kinase inhibitor
erlotinib hydrochloride [no description available]	7.86	6	2	hydrochloride; terminal acetylenic compound	antineoplastic agent; protein kinase inhibitor
piboserod Serotonin 5-HT4 Receptor Antagonists: Drugs that bind to but do not activate SEROTONIN 5-HT4 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN RECEPTOR AGONISTS.	2.08	1	0
l 163191 [no description available]	3.07	4	0
dizocilpine [no description available]	2.89	3	0	secondary amino compound; tetracyclic antidepressant	anaesthetic; anticonvulsant; neuroprotective agent; nicotinic antagonist; NMDA receptor antagonist
bd 1047 N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin: sigma receptor ligand; putative sigma receptor antagonist with antidystonic activity	2.08	1	0	primary amine
s-benzylcysteine [no description available]	2.89	3	0	S-aryl-L-cysteine zwitterion
chelidonine chelidonine: benzophenanthridine derived from scoulerine from Chelidonium majus; RN given refers to parent cpd (chelidonine, (5bR-(5balpha,6beta,12alpha))-isomer)	2.89	3	0	alkaloid antibiotic; alkaloid fundamental parent; benzophenanthridine alkaloid
lapatinib [no description available]	3.25	5	0	furans; organochlorine compound; organofluorine compound; quinazolines	antineoplastic agent; tyrosine kinase inhibitor
sorafenib [no description available]	16.55	66	10	(trifluoromethyl)benzenes; aromatic ether; monochlorobenzenes; phenylureas; pyridinecarboxamide	angiogenesis inhibitor; anticoronaviral agent; antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; ferroptosis inducer; tyrosine kinase inhibitor
lenalidomide [no description available]	3.58	2	0	aromatic amine; dicarboximide; isoindoles; piperidones	angiogenesis inhibitor; antineoplastic agent; immunomodulator
N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide [no description available]	2.08	1	0	aminoquinoline
roxindole [no description available]	2.89	3	0	indoles	alpha-adrenergic antagonist; serotonergic drug
sr 142806 [no description available]	2.08	1	0
conidendrin [no description available]	2.89	3	0
Porfiromycine [no description available]	2.89	3	0	mitomycin
nsc 95397 [no description available]	2.89	3	0	1,4-naphthoquinones
4-methyl-2-quinazolinamine 4-methyl-2-quinazolinamine: from Streptomyces of TCM plant; structure in first source	2.89	3	0
2-glycineamide-5-chlorophenyl-2-pyrryl ketone [no description available]	2.89	3	0
elesclomol [no description available]	2.08	1	0	carbohydrazide; thiocarbonyl compound	antineoplastic agent; apoptosis inducer
niguldipine hydrochloride [no description available]	2.63	2	0
2,5-bis(5-hydroxymethyl-2-thienyl)furan [no description available]	2.89	3	0	thiophenes
nsc 663284 NSC 663284: structure in first source	2.08	1	0	quinolone
bortezomib [no description available]	4.39	3	0	amino acid amide; L-phenylalanine derivative; pyrazines	antineoplastic agent; antiprotozoal drug; protease inhibitor; proteasome inhibitor
ritonavir Ritonavir: An HIV protease inhibitor that works by interfering with the reproductive cycle of HIV. It also inhibits CYTOCHROME P-450 CYP3A.. ritonavir : An L-valine derivative that is L-valinamide in which alpha-amino group has been acylated by a [(2-isopropyl-1,3-thiazol-4-yl)methyl]methylcarbamoyl group and in which a hydrogen of the carboxamide amino group has been replaced by a (2R,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl group. A CYP3A inhibitor and antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS, it is often used as a fixed-dose combination with another protease inhibitor, lopinavir. Also used in combination with dasabuvir sodium hydrate, ombitasvir and paritaprevir (under the trade name Viekira Pak) for treatment of chronic hepatitis C virus genotype 1 infection as well as cirrhosis of the liver.	2.89	3	0	1,3-thiazoles; carbamate ester; carboxamide; L-valine derivative; ureas	antiviral drug; environmental contaminant; HIV protease inhibitor; xenobiotic
bardoxolone methyl methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate: structure in first source	2.53	2	0	cyclohexenones
nsc 23766 [no description available]	2.08	1	0	aminopyrimidine; aminoquinoline; primary amino compound; secondary amino compound; tertiary amino compound	antiviral agent; apoptosis inducer; EC 3.6.5.2 (small monomeric GTPase) inhibitor; muscarinic antagonist
Destruxin B [no description available]	2.89	3	0	cyclodepsipeptide
tosylphenylalanyl chloromethyl ketone Tosylphenylalanyl Chloromethyl Ketone: An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.. N-tosyl-L-phenylalanyl chloromethyl ketone : The N-tosyl derivative of L-phenylalanyl chloromethyl ketone.	2.89	3	0	alpha-chloroketone; sulfonamide	alkylating agent; serine proteinase inhibitor
6-prenylchrysin 6-prenylchrysin: structure in first source. 6-(3,3-dimethylallyl)chrysin : A dihydroxyflavone that is chrysin substituted by a prenyl group at position 6.	3.51	1	0	7-hydroxyflavonol; dihydroxyflavone
trichostatin a trichostatin A: chelates zinc ion in the active site of histone deacetylases, resulting in preventing histone unpacking so DNA is less available for transcription; do not confuse with TRICHOSANTHIN which is a protein; found in STREPTOMYCES	2.21	1	0	antibiotic antifungal agent; hydroxamic acid; trichostatin	bacterial metabolite; EC 3.5.1.98 (histone deacetylase) inhibitor; geroprotector
gw 3965 GW 3965: a liver X receptor ligand	2.08	1	0	diarylmethane
y 27632 Y 27632: RN given for di-HCl salt; inhibits Rho-associated protein kinase; inhibits calcium sensitization to affect smooth muscle relaxation; structure in first source. Y-27632 : A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme.	2.08	1	0	aromatic amide
6-bromoindirubin-3'-oxime 6-bromoindirubin-3'-oxime: structure in first source. 6-bromoindirubin-3'-oxime : A member of the class of biindoles that is indirubin substituted at position 6 by a bromo group and in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.	2.08	1	0
purvalanol b purvalanol B: protein kinase inhibitor; structure in first source	2.08	1	0	purvalanol	protein kinase inhibitor
y-700 [no description available]	2.08	1	0
repsox RepSox: inhibits TGF-beta signaling; structure in first source appears to be incorrect	2.08	1	0	pyrazolopyridine
roflumilast [no description available]	2.13	1	0	aromatic ether; benzamides; chloropyridine; cyclopropanes; organofluorine compound	anti-asthmatic drug; phosphodiesterase IV inhibitor
sitafloxacin [no description available]	2.21	1	0	fluoroquinolone antibiotic; quinolines; quinolone antibiotic
4,4-difluoro-N-[(1S)-3-[3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]-1-cyclohexanecarboxamide [no description available]	2.08	1	0	tropane alkaloid
2'-c-methylcytidine 2'-C-methylcytidine: structure in first source	2.89	3	0
jp-1302 [no description available]	2.89	3	0
7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one [no description available]	2.89	3	0	benzodiazepine
tenatoprazole Tenatoprazole: structure in first source	2.89	3	0	imidazopyridine
stilbenes Stilbenes: Organic compounds that contain 1,2-diphenylethylene as a functional group.. trans-stilbene : The trans-isomer of stilbene.	3.19	1	0	stilbene
isoliquiritigenin [no description available]	2.31	1	0	chalcones	antineoplastic agent; biological pigment; EC 1.14.18.1 (tyrosinase) inhibitor; GABA modulator; geroprotector; metabolite; NMDA receptor antagonist
s 1033 [no description available]	4.65	7	0	(trifluoromethyl)benzenes; imidazoles; pyridines; pyrimidines; secondary amino compound; secondary carboxamide	anticoronaviral agent; antineoplastic agent; tyrosine kinase inhibitor
5-[(2-fluoroanilino)methyl]-8-quinolinol [no description available]	2.89	3	0	hydroxyquinoline
benidipine hydrochloride [no description available]	2.59	2	0
benidipine benidipine: RN refers to (R,R)-(+-)-isomer	2.21	1	0
2-(1,3-benzoxazol-2-ylamino)-5-spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclopentane]one [no description available]	2.89	3	0	quinazolines
chlorprothixene (E)-chlorprothixene : A chlorprothixene in which the double bond adopts an (E)-configuration.	2.89	3	0	chlorprothixene
mercaptopurine Mercaptopurine: An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.. purine-6-thiol : A thiol that is the tautomer of mercaptopurine.. mercaptopurine : A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.	2.08	1	0	aryl thiol; purines; thiocarbonyl compound	anticoronaviral agent; antimetabolite; antineoplastic agent
jrf 12 N2,N4-dibenzylquinazoline-2,4-diamine: a selective, potent, reversible, and ATP-competitive p97 inhibitor	2.89	3	0
rg108 RG108: DNA methyltransferase inhibitor; structure in first source	2.08	1	0	indolyl carboxylic acid
5-amino-3-(4-methoxyphenyl)-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid ethyl ester [no description available]	2.89	3	0	methoxybenzenes; substituted aniline
stf 083010 [no description available]	2.08	1	0
3-hydroxypyridine, sodium salt [no description available]	2.89	3	0
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1-naphthalenecarboxamide [no description available]	3.07	4	0	naphthalenecarboxamide
5-[(2-bromoanilino)methyl]-8-quinolinol [no description available]	2.89	3	0	hydroxyquinoline
3-amino-n-(4-methoxybenzyl)-4,6-dimethylthieno(2,3-b)pyridine-2-carboxamide 3-amino-N-(4-methoxybenzyl)-4,6-dimethylthieno(2,3-b)pyridine-2-carboxamide: structure in first source	2.89	3	0
N-[(2-methoxyphenyl)methyl]-4-(1-piperidinyl)aniline [no description available]	2.89	3	0	aromatic amine
cct018159 CCT018159: structure in first source. CCT-018159 : A member of the class of pyrazoles that is 1H-pyrazole carrying 1,4-benzodioxane-6-yl and 5-ethyl-2,4-dihydroxyphenyl substituents at positions 4 and 5 respectively.	2.08	1	0	benzodioxine; pyrazoles; resorcinols	antineoplastic agent; apoptosis inducer; Hsp90 inhibitor
1-[4-(4-bromophenyl)-2-thiazolyl]-4-piperidinecarboxamide [no description available]	2.89	3	0	piperidinecarboxamide
secinh3 SecinH3: a small molecule antagonist of cytohesins; structure in first source	2.08	1	0	triazoles
jk184 JK184: structure in first source	2.08	1	0
5-[[2-(trifluoromethyl)anilino]methyl]-8-quinolinol [no description available]	2.89	3	0	hydroxyquinoline
N-[3-[2-[(4-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamide [no description available]	2.89	3	0	acetamides; anilide
5-bromo-N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-thiophenecarboxamide [no description available]	2.89	3	0	aromatic amide; thiophenes
6-amino-1-[2-(3,4-dimethoxyphenyl)ethyl]-2-sulfanylidene-4-pyrimidinone [no description available]	2.89	3	0	dimethoxybenzene
N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide [no description available]	2.89	3	0	aromatic amide
N-[5-[(4-chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl]-5-methyl-3-phenyl-4-isoxazolecarboxamide [no description available]	2.89	3	0	aromatic ether
3-chloro-1-(2,5-dimethoxyphenyl)-4-(1-piperidinyl)pyrrole-2,5-dione [no description available]	2.89	3	0	maleimides
Src Inhibitor-1 Src Inhibitor-1 : A member of the class of quinazolines that is quinazoline which is substituted at position 4 by a p-phenoxyanilino group and at positions 6 and 7 by methoxy groups. It is a potent, competitive dual site (both the ATP- and peptide-binding) Src kinase inhibitor. Src Inhibitor-1 is one of the 'gold standards' for Src kinase inhibition that has been shown to use PP1 or PP2 in parallel with Src-I1 to inhbit Src family kinases.	2.89	3	0	aromatic ether; polyether; quinazolines; secondary amino compound	EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
1-[2-(3,4-dimethoxyphenyl)ethyl]-6-propyl-2-sulfanylidene-7,8-dihydro-5H-pyrimido[4,5-d]pyrimidin-4-one [no description available]	2.89	3	0	dimethoxybenzene
2-phenyl-N-[4-(2-thiazolylsulfamoyl)phenyl]-4-quinolinecarboxamide [no description available]	2.89	3	0	quinolines
xl147 [no description available]	2.15	1	0	aromatic amine; benzothiadiazole; quinoxaline derivative; sulfonamide	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
3-(2,5-dimethyl-1-phenyl-3-pyrrolyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine [no description available]	2.89	3	0	pyrroles
tamoxifen citrate [no description available]	2.08	1	0	citrate salt	angiogenesis inhibitor; anticoronaviral agent
hc-067047 HC-067047: a TRPA1 antagonist; structure in first source	2.08	1	0
bi-78d3 [no description available]	3.07	4	0	aryl sulfide
gsk 3787 [no description available]	2.08	1	0
kartogenin kartogenin: promotes chondrocyte differentiation; structure in first source	2.89	3	0
methyl-thiohydantoin-tryptophan methyl-thiohydantoin-tryptophan: structure in first source	2.08	1	0	organonitrogen compound; organooxygen compound
2-[2-chloro-6-ethoxy-4-[(3-methyl-5-oxo-1-phenyl-4-pyrazolylidene)methyl]phenoxy]acetic acid methyl ester [no description available]	2.08	1	0	monocarboxylic acid
4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1h-pyrazol-1-yl)benzenesulfonamide [no description available]	2.08	1	0	sulfonamide
LSM-1318 [no description available]	2.08	1	0	oxa-steroid
toremifene Toremifene: A first generation selective estrogen receptor modulator (SERM). Like TAMOXIFEN, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue.	2.21	1	0	aromatic ether; organochlorine compound; tertiary amine	antineoplastic agent; bone density conservation agent; estrogen antagonist; estrogen receptor modulator
rwj 67657 RWJ 67657: inhibits p38 mitogen-activated protein kinase; structure in first source	2.08	1	0
6-methyl-2-(phenylethynyl)pyridine 6-methyl-2-(phenylethynyl)pyridine: an mGlu5 antagonist. 2-methyl-6-(phenylethynyl)pyridine : A methylpyridine that coinsists of 2-methylp[yridine bearing an additional phenylethynyl group at position 6. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.	2.08	1	0	acetylenic compound; methylpyridines	anxiolytic drug; metabotropic glutamate receptor antagonist
bms 387032 N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-piperidinecarboxamide: a CDK2 inhibitor with antineoplastic activity; structure in first source. N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of piperidine-4-carboxylic acid with the amino group of 5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-amine. It is an ATP-competitive inhibitor of CDK2, CDK7 and CDK9 kinases and exhibits anti-cancer properties.	2.52	2	0	1,3-oxazoles; 1,3-thiazoles; organic sulfide; piperidinecarboxamide; secondary carboxamide	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
lithium Lithium: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.	3.19	1	0	alkali metal atom
sf 2370 SF 2370: indolocarbazole isolated from Actinomadura sp. SF-2370; structure given in first source. K-252a : A organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252a	2.15	1	0	bridged compound; gamma-lactam; methyl ester; organic heterooctacyclic compound	antimicrobial agent; bacterial metabolite; EC 2.7.11.13 (protein kinase C) inhibitor; tropomyosin-related kinase B receptor antagonist
ly335979 [no description available]	2.13	1	0	carbopolycyclic compound
tandutinib [no description available]	2.52	2	0	aromatic ether; N-arylpiperazine; N-carbamoylpiperazine; phenylureas; piperidines; quinazolines; tertiary amino compound	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
vx-745 [no description available]	3.07	4	0	aryl sulfide; dichlorobenzene; difluorobenzene; pyrimidopyridazine	anti-inflammatory drug; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
corlanor ivabradine hydrochloride : A hydrochloride obtained by combining ivabradine with one molar equivalent of hydrochloric acid. Used to treat patients with angina who have intolerance to beta blockers and/or heart failure.	2.08	1	0	hydrochloride	cardiotonic drug
dasatinib N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-1,3-thiazole-5-carboxamide: a dasatinib prodrug; structure in first source. dasatinib (anhydrous) : An aminopyrimidine that is 2-methylpyrimidine which is substituted at position 4 by the primary amino group of 2-amino-1,3-thiazole-5-carboxylic acid and at position 6 by a 4-(2-hydroxyethyl)piperazin-1-yl group, and in which the carboxylic acid group has been formally condensed with 2-chloro-6-methylaniline to afford the corresponding amide. A multi-targeted kinase inhibitor, it is used, particularly as the monohydrate, for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia. Note that the name 'dasatinib' is used to refer to the monohydrate (USAN) as well as to anhydrous dasatinib (INN).	7.85	16	0	1,3-thiazoles; aminopyrimidine; monocarboxylic acid amide; N-(2-hydroxyethyl)piperazine; N-arylpiperazine; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antineoplastic agent; tyrosine kinase inhibitor
ha 1100 HA 1100: intracellular calcium antagonist	2.15	1	0
7-epi-hydroxystaurosporine [no description available]	2.15	1	0
zd 6474 CH 331: structure in first source	10.28	45	1	aromatic ether; organobromine compound; organofluorine compound; piperidines; quinazolines; secondary amine	antineoplastic agent; tyrosine kinase inhibitor
N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide [no description available]	2.63	2	0	indoles
compound 968 compound 968: a glutaminase inhibitor. 5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]phenanthridin-4(1H)-one : A partially hydrogenated benzophenanthridine carrying an oxo group at C-4, geminal methyl groups at C-2 and a 3-bromo-4-(dimethylamino)phenyl group at C-5.	2.08	1	0	benzophenanthridine	EC 3.5.1.2 (glutaminase) inhibitor
nih-12848 NIH-12848: inhibits phosphatidylinositol 5-phosphate 4-kinase gamma; structure in first source	2.89	3	0
2,4-dioxo-3-pentyl-N-[3-(1-piperidinyl)propyl]-1H-quinazoline-7-carboxamide [no description available]	2.89	3	0	quinazolines
[1-(3-methylphenyl)-5-benzimidazolyl]-(1-piperidinyl)methanone [no description available]	2.89	3	0	benzimidazoles
2-[[(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]benzonitrile [no description available]	2.89	3	0	imidazopyridine
3-[(3-fluorophenyl)methyl]-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one [no description available]	2.89	3	0	aromatic ketone
sb-224289 SB 224289 : A member of the class of benzamides obtained by formal condensation of the carboxy group of 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid with the secondary amino group of 1'-methyl-6,7-dihydro-5H-spiro[furo[2,3-f]indole-3,4'-piperidine]. Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays >60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo.	2.08	1	0	1,2,4-oxadiazole; azaspiro compound; benzamides; organic heterotetracyclic compound	serotonergic antagonist
4-[[7-[(4-fluorophenyl)methyl]-1,3-dimethyl-2,6-dioxo-8-purinyl]methyl]-1-piperazinecarboxylic acid ethyl ester [no description available]	2.89	3	0	oxopurine
gw 7647 GW 7647: a PPAR-alpha agonist; structure in first source. GW 7647 : A monocarboxylic acid that is 2-(phenylsulfanyl)isobutyric acid in which the phenyl group is substituted at the para- position by a 3-aza-7-cyclohexylhept-1-yl group in which the nitrogen is acylated by a (cyclohexylamino)carbonyl group.	2.08	1	0	aryl sulfide; monocarboxylic acid; ureas	PPARalpha agonist
N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloroethyl) ester [no description available]	2.89	3	0	organonitrogen compound; organosulfur compound
6-bromo-2-(4-methylphenyl)-N-[(1-methyl-4-pyrazolyl)methyl]-4-quinolinecarboxamide [no description available]	2.89	3	0	quinolines
l 663536 MK-886: orally active leukotriene biosynthesis inhibitor. 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid : A member of the class of indoles that is 1H-indole substituted by a isopropyl group at position 5, a tert-butylsulfanediyl group at position 3, a 4-chlorobenzyl group at position 1 and a 2-carboxy-2-methylpropyl group at position 2. It acts as an inhibitor of arachidonate 5-lipoxygenase.	2.08	1	0	aryl sulfide; indoles; monocarboxylic acid; monochlorobenzenes	antineoplastic agent; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; leukotriene antagonist
LSM-1924 [no description available]	2.89	3	0	organic heterotricyclic compound; organooxygen compound
1-[6-(4-chlorophenyl)-5-imidazo[2,1-b]thiazolyl]-N-[(3,4-dichlorophenyl)methoxy]methanimine [no description available]	2.08	1	0	imidazoles
N4-ethyl-N6,1,2-trimethyl-N4-phenylpyrimidin-1-ium-4,6-diamine [no description available]	2.08	1	0	aromatic amine; tertiary amino compound
ferrostatin-1 ferrostatin-1: inhibits ferroptosis, an iron-dependent form of nonapoptotic cell death; structure in first source. ferrostatin-1 : An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals.	2.89	3	0	ethyl ester; primary arylamine; substituted aniline	antifungal agent; antioxidant; ferroptosis inhibitor; neuroprotective agent; radiation protective agent; radical scavenger
2-[[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxo-5-isoquinolinyl]oxy]propanoic acid ethyl ester [no description available]	2.08	1	0	isoquinolines
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione: a GSK3beta inhibitor. TDZD-8 : A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a methyl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta). An experimental compound which was being developed for the potential treatment of Alzheimer's disease.	2.15	1	0	benzenes; thiadiazolidine	anti-inflammatory agent; antineoplastic agent; apoptosis inducer; EC 2.7.11.26 (tau-protein kinase) inhibitor; neuroprotective agent
sch 79797 [no description available]	2.08	1	0	quinazolines
6-(2-methyl-1-piperidinyl)-5-nitro-4-pyrimidinamine [no description available]	2.89	3	0	C-nitro compound
osteoprotegerin Osteoprotegerin: A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.	2.57	2	0	long-chain fatty acid
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide: a TGF-beta type I receptor kinase activity inhibitor	2.08	1	0	benzamides; benzodioxoles; imidazoles; pyridines	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
rabeprazole(1-) [no description available]	2.63	2	0	organic nitrogen anion
1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one [no description available]	2.08	1	0	monobactam
imd 0354 N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide: a cardioprotective agent that inhibits IkappaB kinase beta (IKKbeta); structure in first source	2.52	2	0	benzamides
ex 527 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide: structure in first source. 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide : A member of the class of carbazoles that is 2,3,4,9-tetrahydro-1H-carbazole which is substituted at position 1 by an aminocarbohyl group and at position 6 by a chlorine.	2.08	1	0	carbazoles; monocarboxylic acid amide; organochlorine compound
ncgc00099374 [no description available]	2.89	3	0
2-nitro-4-[(6-nitro-4-quinolinyl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide [no description available]	2.89	3	0	benzamides
quercetin [no description available]	2.08	1	0	7-hydroxyflavonol; pentahydroxyflavone	antibacterial agent; antineoplastic agent; antioxidant; Aurora kinase inhibitor; chelator; EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor; geroprotector; phytoestrogen; plant metabolite; protein kinase inhibitor; radical scavenger
bilirubin [no description available]	9.72	1	1	biladienes; dicarboxylic acid	antioxidant; human metabolite; mouse metabolite
luteolin [no description available]	2.89	3	0	3'-hydroxyflavonoid; tetrahydroxyflavone	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; c-Jun N-terminal kinase inhibitor; EC 2.3.1.85 (fatty acid synthase) inhibitor; immunomodulator; nephroprotective agent; plant metabolite; radical scavenger; vascular endothelial growth factor receptor antagonist
cyclosporine [no description available]	2.21	1	0
kaempferol [no description available]	2.89	3	0	7-hydroxyflavonol; flavonols; tetrahydroxyflavone	antibacterial agent; geroprotector; human blood serum metabolite; human urinary metabolite; human xenobiotic metabolite; plant metabolite
genistein [no description available]	3.07	4	0	7-hydroxyisoflavones	antineoplastic agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; geroprotector; human urinary metabolite; phytoestrogen; plant metabolite; tyrosine kinase inhibitor
montelukast montelukast: a leukotriene D4 receptor antagonist	2.13	1	0	aliphatic sulfide; monocarboxylic acid; quinolines	anti-arrhythmia drug; anti-asthmatic drug; leukotriene antagonist
mycophenolate mofetil mycophenolate mofetil : A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases.	2.89	3	0	carboxylic ester; ether; gamma-lactone; phenols; tertiary amino compound	anticoronaviral agent; EC 1.1.1.205 (IMP dehydrogenase) inhibitor; immunosuppressive agent; prodrug
bruceantin [no description available]	2.89	3	0	triterpenoid
chrysin chrysin : A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.	2.89	3	0	7-hydroxyflavonol; dihydroxyflavone	anti-inflammatory agent; antineoplastic agent; antioxidant; EC 2.7.11.18 (myosin-light-chain kinase) inhibitor; hepatoprotective agent; plant metabolite
daidzein [no description available]	2.89	3	0	7-hydroxyisoflavones	antineoplastic agent; EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor; EC 3.2.1.20 (alpha-glucosidase) inhibitor; phytoestrogen; plant metabolite
isotretinoin Isotretinoin: A topical dermatologic agent that is used in the treatment of ACNE VULGARIS and several other skin diseases. The drug has teratogenic and other adverse effects.. isotretinoin : A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases.	2.11	1	0	retinoic acid	antineoplastic agent; keratolytic drug; teratogenic agent
neticonazole neticonazole: RN refers to (E)-isomer. neticonazole : An enamine that is ethene which is substituted at positions 1, 1, and 2 by o-pentoxyphenyl, 1H-imidazol-1-yl, and methylthio groups, respectively (the E isomer). An inhibitor of P450-dependent C-14alpha-demethylation of lanosterol (preventing conversion to ergosterol and inhibiting cell wall synthesis in fungi), it is used in Japan (generally as the corresponding hydrochloride salt) as an antifungal drug for the treatment of superficial skin infections.	2.89	3	0	aromatic ether; benzenes; conazole antifungal drug; enamine; imidazole antifungal drug; imidazoles; methyl sulfide	antifungal drug; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
pitavastatin pitavastatin : A dihydroxy monocarboxylic acid that is (6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]hept-6-enoic acid in which the two hydroxy groups are located at positions 3 and 5 (the 3R,5S-stereoisomer). Used as its calcium salt for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise.	2.13	1	0	cyclopropanes; dihydroxy monocarboxylic acid; monofluorobenzenes; quinolines; statin (synthetic)	antioxidant
N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine synaptamide: structurally similar to the endocannabinoid N-arachidonoylethanolamine (anandamide). N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine : An N-acylethanolamine 22:6 that is the ethanolamide of (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoic acid.	2.89	3	0	endocannabinoid; N-acylethanolamine 22:6
n-oleoylethanolamine N-oleoylethanolamine: ceramidase inhibitor. oleoyl ethanolamide : An N-(long-chain-acyl)ethanolamine that is the ethanolamide of oleic acid. The monounsaturated analogue of the endocannabinoid anandamide.	2.89	3	0	endocannabinoid; N-(long-chain-acyl)ethanolamine; N-acylethanolamine 18:1	EC 3.5.1.23 (ceramidase) inhibitor; geroprotector; PPARalpha agonist
nalmefene nalmefene: RN given refers to 5-alpha isomer	2.13	1	0	morphinane alkaloid
sirolimus Sirolimus: A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.. sirolimus : A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent.	11.4	13	5	antibiotic antifungal drug; cyclic acetal; cyclic ketone; ether; macrolide lactam; organic heterotricyclic compound; secondary alcohol	antibacterial drug; anticoronaviral agent; antineoplastic agent; bacterial metabolite; geroprotector; immunosuppressive agent; mTOR inhibitor
alpha-zearalenol [no description available]	2.89	3	0	macrolide
alvocidib alvocidib: structure given in first source. alvocidib : A synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is substituted by a 3-hydroxy-1-methylpiperidin-4-yl group at position 8 and by a chlorine at the 2' position (the (-)-3S,4R stereoisomer). A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation.	2.15	1	0	dihydroxyflavone; hydroxypiperidine; monochlorobenzenes; tertiary amino compound	antineoplastic agent; antirheumatic drug; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
fenretinide Fenretinide: A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.. 4-hydroxyphenyl retinamide : A retinoid obtained by formal condensation of the carboxy group of all-trans retinoic acid and the anilino group of 4-hydroxyaniline. Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids.	2.08	1	0	monocarboxylic acid amide; retinoid	antineoplastic agent; antioxidant
su 9516 [no description available]	2.89	3	0
N-(4-bromo-3-methylphenyl)-2,5-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine [no description available]	2.89	3	0	triazolopyrimidines
ter 199 [no description available]	2.08	1	0
arachidonylcyclopropylamide arachidonylcyclopropylamide: a potent and selective agonist of neuronal cannabinoid receptor; structure in first source	2.08	1	0
sb 277011 SB 277011: structure in first source	2.89	3	0
ly 320135 LY 320135: cannabinoid receptor antagonist; structure in first source	2.08	1	0	benzofurans
pd 166285 [no description available]	2.08	1	0
sb 223412 SB 223412: SB-223412 is the (S)-(-)-isomer; RN given for (S)-isomer; structure in first source	2.89	3	0
sr 59230a [no description available]	2.89	3	0	tetralins
3-[6-[4-(trifluoromethoxy)anilino]-4-pyrimidinyl]benzamide [no description available]	2.89	3	0	pyrimidines
kn 62 KN 62: inhibitor of Ca/calmodulin-dependent protein kinase II	3.07	4	0	piperazines
su 6656 SU 6656: a c-Src kinase inhibitor; used to probe growth signaling; structure in first source. SU6656 : A member of the class of oxindoles that is 3-methyleneoxindole in which the hydrogeh at position 5 has been replaced by a dimethylaminosulfonyl group and in which one of the hydrogens of the methylene group has been replaced by a 4,5,6,7-tetrahydro-indol-2-yl group. It is a specific inhibitor of Src family kinase.	2.08	1	0
MeJA [no description available]	2.89	3	0	Jasmonate derivatives
1h-pyrrole-2,5-dione, 3-(1-methyl-1h-indol-3-yl)-4-(1-methyl-6-nitro-1h-indol-3-yl)- 1H-pyrrole-2,5-dione, 3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-6-nitro-1H-indol-3-yl)-: structure in first source	2.89	3	0
pd 161570 PD 161570: structure in first source	2.89	3	0
bosutinib 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile: a Src kinase inhibitor; structure in first source	2.57	2	0	aminoquinoline; aromatic ether; dichlorobenzene; N-methylpiperazine; nitrile; tertiary amino compound	antineoplastic agent; tyrosine kinase inhibitor
semaxinib semaxanib : An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is replaced by a 3,5-dimethylpyrrol-2-yl group.	2.08	1	0	olefinic compound; oxindoles; pyrroles	angiogenesis modulating agent; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; vascular endothelial growth factor receptor antagonist
orantinib orantinib: an antiangiogenic agent. orantinib : An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 2-(2-carboxyethyl)-3,5-dimethylpyrrol-3-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth factor receptor 1.	2.15	1	0
su 11248 [no description available]	17.58	83	22	monocarboxylic acid amide; pyrroles	angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; immunomodulator; neuroprotective agent; vascular endothelial growth factor receptor antagonist
palbociclib [no description available]	3.42	6	0	aminopyridine; aromatic ketone; cyclopentanes; piperidines; pyridopyrimidine; secondary amino compound; tertiary amino compound	antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
jnj-7706621 [no description available]	3.07	4	0	sulfonamide
fosbretabulin fosbretabulin: a microtubule destabilizing agent isolated from Combretum caffrum; structure in first source	3.19	1	0
3,3',4,5'-tetramethoxy-trans-stilbene (E)-3,4,3',5'-tetramethoxystilbene: from the leaves of Eugenia rigida; structure in first source	3.51	1	0
virginiamycin factor s1 virginiamycin factor S1: a component of VIRGINIAMYCIN; was EP to VIRGINIAMYCIN 1992-2001. virginiamycin S1 : A cyclodepsipeptide that is N-(3-hydroxypicolinoyl)-L-threonyl-D-alpha-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine in which the carboxy group of the 2-phenylglycine moiety has undergone formal intramolecular condensation with the hydroxy group of the N-(3-hydroxypicolinoyl)-L-threonyl to give the corresponding 19-membered ring lactone. It is one of the two major components of the antibacterial drug virginiamycin, produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others.	2.89	3	0	cyclodepsipeptide; macrolide antibiotic	antibacterial drug; bacterial metabolite
cisplatin [no description available]	2.08	1	0	diamminedichloroplatinum	antineoplastic agent; apoptosis inducer; cross-linking reagent; ferroptosis inducer; genotoxin; mutagen; nephrotoxin; photosensitizing agent
benzoporphyrin d benzoporphyrin D: C42H44N4O8, MW 732.821	2.13	1	0
vx680 [no description available]	2.52	2	0	N-arylpiperazine
fenoterol fenoterol hydrobromide : The hydrobromide salt of fenoterol. A beta2-adrenergic agonist, it is used as a bronchodilator in the management of reversible airway obstruction.	2.63	2	0	hydrobromide	beta-adrenergic agonist; bronchodilator agent; sympathomimetic agent
xib 4035 XIB 4035: a GFRalpha-1 agonist; structure in first source	2.89	3	0
gw-5074 [no description available]	2.21	1	0
radium Radium: A radioactive element of the alkaline earth series of metals. It has the atomic symbol Ra and atomic number 88. Radium is the product of the disintegration of URANIUM and is present in pitchblende and all ores containing uranium. It is used clinically as a source of beta and gamma-rays in radiotherapy, particularly BRACHYTHERAPY.	5.39	5	0	alkaline earth metal atom
d 4476 [no description available]	2.08	1	0	imidazoles
cyc 116 4-methyl-5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)thiazol-2-amine: an aurora kinase inhibitor; structure in first source	2.81	3	0
bay 19-8004 BAY 19-8004: a PDE4 inhibitor; structure in first source	2.08	1	0
everolimus [no description available]	16.55	53	22	cyclic acetal; cyclic ketone; ether; macrolide lactam; primary alcohol; secondary alcohol	anticoronaviral agent; antineoplastic agent; geroprotector; immunosuppressive agent; mTOR inhibitor
ekb 569 EKB 569: an EGF receptor kinase inhibitor	2.54	2	0	aminoquinoline; monocarboxylic acid amide; monochlorobenzenes; nitrile	protein kinase inhibitor
axitinib [no description available]	10.57	37	2	aryl sulfide; benzamides; indazoles; pyridines	antineoplastic agent; tyrosine kinase inhibitor; vascular endothelial growth factor receptor antagonist
pai 039 tiplaxtinin: inhibitor of plasminogen activator inhibitor-1	2.08	1	0	indole-3-acetic acids
belotecan belotecan: structure in first source	2.89	3	0	pyranoindolizinoquinoline
tanespimycin CP 127374: analog of herbimycin A	3.17	1	0	1,4-benzoquinones; ansamycin; carbamate ester; organic heterobicyclic compound; secondary amino compound	antineoplastic agent; apoptosis inducer; Hsp90 inhibitor
verlukast verlukast: LTD4 receptor antagonist	2.13	1	0
norgestimate [no description available]	2.89	3	0	ketoxime; steroid ester; terminal acetylenic compound	contraceptive drug; progestin; synthetic oral contraceptive
b 43 RK-24466 : A member of the class of pyrrolopyrimidines that is 7H-pyrrolo[2,3-d]pyrimidine substituted by amino, 4-phenoxyphenyl, and cyclopentyl groups at positions 4, 5 and 7, respectively. It is a potent inhibitor of Lck that inhibits Lck (64-509) and LckCD isoforms (IC50 of less than 1 and 2 nM, respectively).	2.89	3	0	aromatic amine; aromatic ether; cyclopentanes; primary amino compound; pyrrolopyrimidine	EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; geroprotector
gw2974 GW2974: quinazoline derivative, which is able to block the activation of both the EGFR and erbB2	2.08	1	0	pyridopyrimidine
4-(2' methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-fluorobenzamido)ethyl)piperazine [no description available]	2.89	3	0
methiazole methiazole: a parasitostatic agent	2.89	3	0	benzimidazoles; carbamate ester
sb 218795 SB 218795: structure in first source	2.89	3	0	quinolines
bvt.948 [no description available]	2.89	3	0
ispinesib [no description available]	2.08	1	0	benzamides
fk 866 N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide: inhibits nicotinamide phosphoribosyltransferase; structure in first source	2.21	1	0	benzamides; N-acylpiperidine
a 38503 [no description available]	2.89	3	0
temsirolimus [no description available]	3.91	3	0	macrolide lactam
pd 184352 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide: inhibits MAP kinase kinase; structure in first source	2.08	1	0	aminobenzoic acid
bibx 1382bs BIBX 1382BS: an ErbB receptor kinase inhibitor; no further information available 4/2001	2.08	1	0	substituted aniline
on 01910 ON 01910: a Plk1 inhibitor with antineoplastic activity; structure in first source. N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine : A glycine derivative that is glycine in which one of the hydrogens of the amino group is substituted by a 2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl group.. rigosertib : An N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine in which the double bond has E-configuration. It is a non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM and exhibits anti-cancer properties.	2.15	1	0	N-[2-methoxy-5-({[2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl}methyl)phenyl]glycine	antineoplastic agent; apoptosis inducer; EC 2.7.11.21 (polo kinase) inhibitor; microtubule-destabilising agent
hdac-42 HDAC-42: structure in first source	2.08	1	0	amidobenzoic acid
parthenolide [no description available]	2.58	2	0	sesquiterpene lactone	drug allergen; inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; peripheral nervous system drug
krn 633 N-(2-chloro-4-((6,7-dimethoxy-4-quinazolinyl)oxy)phenyl)-N'-propylurea: a VEGF receptor-2 tyrosine kinase inhibitor; structure in first source	2.89	3	0
[4-[[4-(1-benzothiophen-2-yl)-2-pyrimidinyl]amino]phenyl]-[4-(1-pyrrolidinyl)-1-piperidinyl]methanone [no description available]	2.08	1	0	benzamides; N-acylpiperidine
s 1743 Esomeprazole: The S-isomer of omeprazole.. esomeprazole : A 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole that has S configuration at the sulfur atom. An inhibitor of gastric acid secretion, it is used (generally as its sodium or magnesium salt) for the treatment of gastro-oesophageal reflux disease, dyspepsia, peptic ulcer disease, and Zollinger-Ellison syndrome.	3.5	1	1	magnesium salt	anti-ulcer drug; EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
5-amino-4-oxo-3-phenyl-1-thieno[3,4-d]pyridazinecarboxylic acid [no description available]	2.89	3	0	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
iniparib [no description available]	2.08	1	0	carbonyl compound; organohalogen compound
orteronel orteronel: non-steroidal 17,20-lyase inhibitor; structure in first source	2.08	1	0
mk 0752 [no description available]	2.08	1	0
gw 501516 GW 501516: a selective PPARdelta agonist; structure in first source. GW 501516 : An aromatic ether that is phenoxyacetic acid in which the phenyl group is substituted at position 2 by a methyl group and at position 4 by a (1,3-thiazol-5-ylmethyl)sulfanediyl group, and in which the 1,3-thiazolyl group is substituted at positions 2 and 4 by p-trifluoromethylphenyl and methyl groups, respectively.	3.07	4	0	1,3-thiazoles; aromatic ether; aryl sulfide; monocarboxylic acid; organofluorine compound	carcinogenic agent; PPARbeta/delta agonist
av 412 [no description available]	2.52	2	0
ag-041r AG-041R: structure in first source	2.08	1	0
telatinib [no description available]	2.52	2	0
y-39983 Y-39983: SNJ-1656 is an ophthalmic solution of Y-39983; ROCK (rho kinase) inhibitor, promotes regeneration of crushed axons of retinal ganglion cells; structure in first source	2.15	1	0	pyrrolopyridine
dolastatin 10 dolastatin 10: from mollusk Dolabella auricularia; contains four amino acids, dolavaline, dolaisoleucine, dolaproine, valine and the primary amine dolaphenine; deo-dolastatin 10 is a new dolastatin 10 chiral derivative with MW of 784. dolastatin 10 : A tetrapeptide that is isolated from the sea hare Dolabella auricularia. It is a potent anticancer agent which inhibits tubulin polymerization.	2.89	3	0	1,3-thiazoles; tetrapeptide	animal metabolite; antineoplastic agent; apoptosis inducer; marine metabolite; microtubule-destabilising agent
cp 547632 3-(4-bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide: inhibits vascular endothelial growth factor receptor-2 tyrosine kinase; structure in first source	2.52	2	0
spc-839 SPC-839: an inhibitor of activator protein 1; structure in first source	3.07	4	0
abiraterone acetate Abiraterone Acetate: An androstene derivative that inhibits STEROID 17-ALPHA-HYDROXYLASE and is used as an ANTINEOPLASTIC AGENT in the treatment of metastatic castration-resistant PROSTATE CANCER.. abiraterone acetate : A sterol ester obtained by formal condensation of the 3-hydroxy group of abiraterone with the carboxy group of acetic acid. A prodrug that is converted in vivo into abiraterone. Used for treatment of metastatic castrate-resistant prostate cancer.	3.17	1	0	pyridines; sterol ester	antineoplastic agent; EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor; prodrug
lenvatinib lenvatinib : A member of the class of quinolines that is the carboxamide of 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxylic acid. A multi-kinase inhibitor and orphan drug used (as its mesylate salt) for the treatment of various types of thyroid cancer that do not respond to radioiodine.	15.19	55	5	aromatic amide; aromatic ether; cyclopropanes; monocarboxylic acid amide; monochlorobenzenes; phenylureas; quinolines	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; fibroblast growth factor receptor antagonist; orphan drug; vascular endothelial growth factor receptor antagonist
andarine [no description available]	2.08	1	0	acetamides; anilide
gw843682x [no description available]	2.08	1	0	(trifluoromethyl)benzenes
pd 0325901 mirdametinib: has antineoplastic activity; appears to be a MEK inhibitor. PD 0325901 : A hydroxamic acid ester that is benzhydroxamic acid (N-hydroxybenzamide) in which the hydroxamic acid group has been converted to the corresponding 2,3-dihydroxypropyl ester and in which the benzene ring has been substituted at position 2 by a (2-fluoro-4-iodophenyl)amino group and at positions 3 and 4 by fluorines (the R enantiomer).	2.52	2	0	difluorobenzene; hydroxamic acid ester; monofluorobenzenes; organoiodine compound; propane-1,2-diols; secondary amino compound	antineoplastic agent; EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor
midostaurin midostaurin : An organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine.	3.25	5	0	benzamides; gamma-lactam; indolocarbazole; organic heterooctacyclic compound	antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor
ag 14361 [no description available]	2.08	1	0	benzimidazoles
sb 265610 [no description available]	2.08	1	0
px-866 PX-866: inhibitor of phosphoinositide-3-kinase signaling with antitumor activity; structure in first source. PX-866 : An organic heterotetracyclic compound that is obtained from wortmanin via aminolysis of its furan ring by diallyl amine.	2.15	1	0	acetate ester; delta-lactone; organic heterotetracyclic compound; tertiary amino compound	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
valnemulin [no description available]	2.63	2	0
cabazitaxel cabazitaxel: an antineoplastic agent; structure in first source. cabazitaxel : A tetracyclic diterpenoid that is 10-deacetylbaccatin III having O-methyl groups attached at positions 7 and 10 as well as an O-(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl group attached at position 13. Acts as a microtubule inhibitor, binds tubulin and promotes microtubule assembly and simultaneously inhibits disassembly.	7.12	6	0	tetracyclic diterpenoid	antineoplastic agent; microtubule-stabilising agent
nu 7026 2-(morpholin-4-yl)benzo(h)chromen-4-one: a radiosensitizing agent that inhibits DNA-dependent protein kinase; structure in first source	2.89	3	0	organic heterotricyclic compound; organooxygen compound
ripasudil [no description available]	2.15	1	0	isoquinolines
fr 148083 5Z-7-oxozeaenol : A macrolide that is the 7-oxo derivative of zeaenol (the 5Z stereoisomer). Isolated from Fungi, it exhibits cytotoxic, antibacterial and inhibitory activity against NF-kappaB.	2.08	1	0	aromatic ether; macrolide; phenols; secondary alcohol; secondary alpha-hydroxy ketone	antibacterial agent; antineoplastic agent; metabolite; NF-kappaB inhibitor
mocetinostat mocetinostat: undergoing phase II clinical trials for treatment of cancer. mocetinostat : A benzamide obtained by formal condensation of the carboxy group of 4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzoic acid with one of the amino groups of benzene-1,2-diamine. It is an orally active and isotype-selective HDAC inhibitor which exhibits antitumour activity (IC50 = 0.15, 0.29, 1.66 and 0.59 muM for HDAC1, HDAC2, HDAC3 and HDAC11).	2.08	1	0	aminopyrimidine; benzamides; pyridines; secondary amino compound; secondary carboxamide; substituted aniline	antineoplastic agent; apoptosis inducer; autophagy inducer; cardioprotective agent; EC 3.5.1.98 (histone deacetylase) inhibitor; hepatotoxic agent
osi 930 OSI 930: inhibits both receptor tyrosine kinase Kit and kinase insert domain receptor; structure in first source	3.25	5	0	aromatic amide
ki 20227 [no description available]	2.08	1	0
scio-469 SCIO-469: a small-molecule p38 mitogen-activated protein (MAP) kinase inhibitor for potential oral therapy for inflammatory disorders; in phase lib clinical trials for rheumatoid arthritis 4/2004. talmapimod : An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties.	2.52	2	0	aromatic amide; aromatic ketone; chloroindole; dicarboxylic acid diamide; indolecarboxamide; monofluorobenzenes; N-acylpiperazine; N-alkylpiperazine	antineoplastic agent; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
ticagrelor Ticagrelor: An adenosine triphosphate analogue and reversible P2Y12 PURINORECEPTOR antagonist that inhibits ADP-mediated PLATELET AGGREGATION. It is used for the prevention of THROMBOEMBOLISM by patients with ACUTE CORONARY SYNDROME or a history of MYOCARDIAL INFARCTION.. ticagrelor : A triazolopyrimidine that is an adenosine isostere; the cyclopentane ring is similar to ribose and the nitrogen-rich [1,2,3]triazolo[4,5-d]pyrimidine moiety resembles the nucleobase adenine. A platelet aggregation inhibitor which is used for prevention of thromboembolic events in patients with acute coronary syndrome.	2.89	3	0	aryl sulfide; hydroxyether; organofluorine compound; secondary amino compound; triazolopyrimidines	P2Y12 receptor antagonist; platelet aggregation inhibitor
ssr 69071 SSR 69071: structure in first source	2.08	1	0	pyridopyrimidine
l 692585 [no description available]	2.89	3	0	peptide
cp 724714 2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide: CP-724714 is the ((2E)-isomer, 1:1.5 succinate); structure in first source	2.54	2	0	2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide	antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; hepatotoxic agent
pi103 PI103: pyridofuropyrimidine antineoplastic; a potent inhibitor of class I phosphatidylinositide 3-kinases (PI3K); structure in first soruce	3.07	4	0	aromatic amine; morpholines; organic heterotricyclic compound; phenols; tertiary amino compound	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor
sb 210313 [no description available]	2.08	1	0
3,5-bis(2-fluorobenzylidene)piperidin-4-one 3,5-bis(2-fluorobenzylidene)piperidin-4-one: an antineoplastic agent; structure in first source	2.17	1	0
hmn-214 (E)-4-(2-(2-(N-acetyl-N-(4-methoxybenzenesulfonyl)amino)stilbazole)) 1-oxide: an antineoplastic agent; structure in first source	2.15	1	0
gw 4064 [no description available]	2.08	1	0	stilbenoid
nnc 26-9100 NNC 26-9100: structure in first source	2.89	3	0	aminopyridine
2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine [no description available]	2.89	3	0
sa 4503 [no description available]	2.08	1	0
ic 87114 IC 87114: structure in first source	2.08	1	0	6-aminopurines; biaryl; quinazolines	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
zibotentan ZD4054: a potent endothelin receptor A antagonist that inhibits ovarian carcinoma cell proliferation	2.08	1	0	phenylpyridine
tivozanib N-(2-chloro-4-((6,7-dimethoxy-4-quinolyl)oxy)phenyl)-N'-(5-methyl-3-isoxazolyl)urea: KNR-951 is the HCl, monohydrate salt; an antineoplastic agent; structure in first source	5.75	9	0	aromatic ether
hki 272 [no description available]	3.05	4	0	nitrile; quinolines	antineoplastic agent; tyrosine kinase inhibitor
tofacitinib tofacitinib : A pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis.	7.81	3	0	N-acylpiperidine; nitrile; pyrrolopyrimidine; tertiary amino compound	antirheumatic drug; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
bibr 1532 [no description available]	2.08	1	0
n-(6-chloro-7-methoxy-9h-beta-carbolin-8-yl)-2-methylnicotinamide [no description available]	3.07	4	0
rucaparib AG14447: Poly(ADP-ribose) polymerase inhibitor; structure in first source	2.08	1	0	azepinoindole; caprolactams; organofluorine compound; secondary amino compound	antineoplastic agent; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
cediranib [no description available]	2.52	2	0	aromatic ether
tae226 TAE226: an adhesion kinase inhibitor, offers an attractive therapeutic approach in ovarian carcinoma; structure in first source	2.89	3	0	morpholines
gw0742 GW 610742: structure in first source	3.07	4	0	monocarboxylic acid
ps1145 PS1145: IkappaB kinase inhibitor; structure in first source	2.08	1	0	beta-carbolines
bay 41-8543 BAY 41-8543: structure in first source	2.08	1	0	pyrazolopyridine
u 18666a 3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one: inhibits cycloartenol synthase. 3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride : A hydrochloride obtained by reaction of 3beta-(2-diethylaminoethoxy)androst-5-en-17-one with one equivalent of hydrochloric acid. It is a cholesterol synthesis and transport inhibitor.	2.89	3	0	hydrochloride	antiviral agent; EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor; Hedgehog signaling pathway inhibitor; nicotinic antagonist; sterol biosynthesis inhibitor
chir 99021 Chir 99021: structure in first source. CHIR 99021 : A member of the class of aminopyrimidines that is 2-aminopyrimidine substituted at positions N2, 5 and 6 by (5-cyanopyridin-2-yl)ethyl, 4-methylimidazol-2-yl and 2,4-dichlorophenyl groups respectively.	2.08	1	0	aminopyridine; aminopyrimidine; cyanopyridine; diamine; dichlorobenzene; imidazoles; secondary amino compound	EC 2.7.11.26 (tau-protein kinase) inhibitor
sb 525334 6-(2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline: a TGF-betaR kinase inhibitor	3.07	4	0	quinoxaline derivative
way-362450 [no description available]	2.08	1	0	indoles
masitinib [no description available]	2.52	2	0	1,3-thiazoles; benzamides; N-alkylpiperazine; pyridines	antineoplastic agent; antirheumatic drug; tyrosine kinase inhibitor
bx795 BX795: structure in first source	3.07	4	0	ureas
ly-2157299 LY-2157299: an orally active transforming growth factor beta receptor (TGF-beraR) kinase inhibitor. LY-2157299 : A pyrrolopyrazole that is 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole which is substituted at positions 2 and 3 by 6-methylpyridin-2-yl and 6-(aminocarbonyl)quinolin-4-yl groups, respectively. A Transforming growth factor-betaRI (TGF-betaRI) kinase inhibitor, it blocks TGF-beta-mediated tumor growth in glioblastoma.	2.15	1	0	aromatic amide; methylpyridines; monocarboxylic acid amide; pyrrolopyrazole; quinolines	antineoplastic agent; TGFbeta receptor antagonist
pazopanib pazopanib: a protein kinase inhibitor. pazopanib : A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer.	9.61	30	1	aminopyrimidine; indazoles; sulfonamide	angiogenesis modulating agent; antineoplastic agent; tyrosine kinase inhibitor; vascular endothelial growth factor receptor antagonist
sepantronium sepantronium: a survivin suppressant with antineoplastic activity. sepantronium : An organic cation that is 1-(2-methoxyethyl)-2-methyl-1H-naphtho[2,3-d]imidazole-4,9-dione in which the nitrogen at position 3 of the napthoimidazole moiety has been alkylated by a pyrazin-2-ylmethyl group.	2.08	1	0	organic cation
azd 6244 AZD 6244: a MEK inhibitor	3.39	6	0	benzimidazoles; bromobenzenes; hydroxamic acid ester; monochlorobenzenes; organofluorine compound; secondary amino compound	anticoronaviral agent; antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
su 14813 5-((5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl)-N-(2-hydroxy-3-morpholin-4-ylpropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide: has both antineoplastic and antiangiogenic activities; structure in first source	2.15	1	0
1-(2-(1-adamantyl)ethyl)-1-pentyl-3-(3-(4-pyridyl)propyl)urea 1-(2-(1-adamantyl)ethyl)-1-pentyl-3-(3-(4-pyridyl)propyl)urea: structure in first source	3.07	4	0
bibw 2992 [no description available]	3.57	7	0	aromatic ether; enamide; furans; monochlorobenzenes; organofluorine compound; quinazolines; secondary carboxamide; tertiary amino compound	antineoplastic agent; tyrosine kinase inhibitor
bay 61-3606 [no description available]	2.89	3	0	pyrimidines
N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide : A member of the class of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-4-carboxylic acid with the amino group of 3-cyanoaniline.	2.08	1	0	1,3,4-oxadiazoles; benzamides; biphenyls; nitrile	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
ar c155858 AR C155858: an MCT1 inhibitor; structure in first source	2.08	1	0
binimetinib binimetinib : A member of the class of benzimidazoles that is 1-methyl-1H-benzimidazole which is substituted at positions 4, 5, and 6 by fluorine, (4-bromo-2-fluorophenyl)nitrilo, and N-(2-hydroxyethoxy)aminocarbonyl groups, respectively. It is a MEK1 and MEK2 inhibitor (IC50= 12 nM). Approved by the FDA for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation in combination with encorafenib.	2.15	1	0	benzimidazoles; bromobenzenes; hydroxamic acid ester; monofluorobenzenes; secondary amino compound	antineoplastic agent; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
sotrastaurin sotrastaurin: a potent protein kinase C-selective inhibitor; structure in first source. sotrastaurin : A member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients.	2.15	1	0	indoles; maleimides; N-alkylpiperazine; N-arylpiperazine; quinazolines	anticoronaviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunosuppressive agent
aee 788 AEE 788: structure in first source	2.52	2	0	6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; epidermal growth factor receptor antagonist; trypanocidal drug
saracatinib [no description available]	2.81	3	0	aromatic ether; benzodioxoles; diether; N-methylpiperazine; organochlorine compound; oxanes; quinazolines; secondary amino compound	anticoronaviral agent; antineoplastic agent; apoptosis inducer; autophagy inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; radiosensitizing agent
sd-208 [no description available]	3.07	4	0
vx 702 VX 702: a p38 MAP kinase inhibitor	2.52	2	0	phenylpyridine
crenolanib [no description available]	3.27	5	0	aminopiperidine; aromatic ether; benzimidazoles; oxetanes; quinolines; tertiary amino compound	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
tg100-115 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol: for treatment of ischemia reperfusion injury; structure in first source	2.15	1	0	pteridines
cj 033466 CJ 033466: structure in first source	2.89	3	0
cc 401 CC 401: an anthrapyrazolone	3.1	4	0	pyrazoles; ring assembly
bms 599626 [no description available]	2.15	1	0
exel-7647 tesevatinib : A member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, methoxy, and [(3aR,5r,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methoxy groups at positions 4, 6 and 7, respectively. It is a multi-target tyrosine kinase inhibitor of EGFR, ErbB2, KDR, Flt4 and EphB4 and exhibits anti-cancer properties.	2.15	1	0
volasertib BI 6727: a polo-like kinase inhibitor with broad antitumor activity; structure in first source	2.81	3	0
pha 665752 [no description available]	3.23	1	0	dichlorobenzene; enamide; indolones; N-acylpyrrolidine; pyrrolecarboxamide; secondary carboxamide; sulfone; tertiary carboxamide	antineoplastic agent; c-Met tyrosine kinase inhibitor
PB28 PB28 : A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.	3.07	4	0	aromatic ether; piperazines; tetralins	anticoronaviral agent; antineoplastic agent; apoptosis inducer; sigma-2 receptor agonist
arterolane arterolane: a trioxolane with antimalarial activity; structure in first source. arterolane : An oxaspiro compound that is dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.1(3,7)]decane] substituted by a 2-[(2-amino-2-methylpropyl)amino]-2-oxoethyl group at position 4s. Its maleic acid salt is used as an antimalarial drug in combination with piperaquine.	2.89	3	0
azd 7762 [no description available]	2.52	2	0	aromatic amide; thiophenes
cariprazine cariprazine: Structure in first source. cariprazine : An N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichlorophenyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder.	2.89	3	0
krp-203 [no description available]	3.07	4	0
mk 0354 [no description available]	2.08	1	0
regorafenib [no description available]	12.48	38	1	(trifluoromethyl)benzenes; aromatic ether; monochlorobenzenes; monofluorobenzenes; phenylureas; pyridinecarboxamide	antineoplastic agent; hepatotoxic agent; tyrosine kinase inhibitor
at 7867 [no description available]	2.89	3	0	monochlorobenzenes; piperidines; pyrazoles	antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
acetic acid 2-[4-methyl-8-(4-morpholinylsulfonyl)-1,3-dioxo-2-pyrrolo[3,4-c]quinolinyl]ethyl ester [no description available]	3.07	4	0	pyrroloquinoline
6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one [no description available]	2.81	3	0	methoxybenzenes; substituted aniline
ptc 124 [no description available]	2.89	3	0	oxadiazole; ring assembly
degrasyn degrasyn: a JAK2 kinase inhibitor that induces rapid degradation of c-Myc protein in MM-1 multiple myeloma and other tumor cell lines; structure in first source	2.63	2	0
brivanib [no description available]	2.52	2	0	aromatic ether; diether; fluoroindole; pyrrolotriazine; secondary alcohol	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; drug metabolite; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; fibroblast growth factor receptor antagonist
icg 001 [no description available]	2.08	1	0	peptide
mp470 [no description available]	2.52	2	0	N-arylpiperazine
rgb 286638 [no description available]	2.15	1	0
np 031112 tideglusib: an NSAID and neuroprotective agent. tideglusib : A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy.	2.15	1	0	benzenes; naphthalenes; thiadiazolidine	anti-inflammatory agent; apoptosis inducer; EC 2.7.11.26 (tau-protein kinase) inhibitor; neuroprotective agent
nu 7441 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one: structure in first source	2.08	1	0	dibenzothiophenes
at 7519 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-pyrazole-3-carboxamide : A member of the class of pryrazoles that is 4-amino-1H-pyrazole-3-carboxylic acid in which the primary amino group has been acylated by a 2,6-dichlorobenzoyl group and in which the carboxylic acid has been converted into a carboxamide by formal condensation with the primary amino group of 4-aminopiperidine.	2.52	2	0	dichlorobenzene; piperidines; pyrazoles; secondary carboxamide	antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
bms-690514 [no description available]	2.54	2	0
bi 2536 [no description available]	3.25	5	0
inno-406 [no description available]	2.15	1	0	biaryl
kw 2449 KW 2449: has both multikinase inhibitory activity and antineoplastic activity; structure in first source	2.15	1	0
danusertib [no description available]	2.52	2	0	piperazines
N-[4-(2-tert-butylphenyl)sulfonylphenyl]-2,3,4-trihydroxy-5-[(2-propan-2-ylphenyl)methyl]benzamide [no description available]	2.08	1	0	benzamides
N-[5-[[5-[(4-acetyl-1-piperazinyl)-oxomethyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[(3,3-dimethylbutan-2-ylamino)methyl]benzamide [no description available]	2.08	1	0	benzamides
nvp-aew541 [no description available]	3.05	4	0
abt 869 [no description available]	2.52	2	0	aromatic amine; indazoles; phenylureas	angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
azd 8931 sapitinib : A member of the class of quinazolines that is 4-amino-7-methoxyquinazoline in which the amino group has been substituted by a 3-chloro-2-fluorophenyl group and in which position 6 of the quinoline ring has been substituted by a {1-[2-(methylamino)-2-oxoethyl]piperidin-4-yl}oxy group. Sapitinib is a dual tyrosine kinase inhibitor (TKI) of epithelial growth factor receptors (EGFR) HER2 and HER3.	2.15	1	0	aromatic ether; monochlorobenzenes; monofluorobenzenes; piperidines; quinazolines; secondary amino compound; tertiary amino compound	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; epidermal growth factor receptor antagonist
arq 197 [no description available]	5.34	6	0	indoles
azd 1152 AZD-1152 : A member of the of quinazolines that is 4-aminoquinazolin-7-ol in which the amino group at position 4 has been substituted by a 5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl group, while the hydroxy group at position 7 has been converted into the corresponding 3-[ethyl(2-hydroxyethyl)aminopropyl ether.	3.1	4	0	anilide; monoalkyl phosphate; monofluorobenzenes; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor; prodrug
pf 00299804 dacomitinib: a pan-ERBB inhibitor. dacomitinib : A member of the class of quinazolines that is 7-methoxyquinazoline-4,6-diamine in which the amino group at position 4 is substituted by a 3-chloro-4-fluorophenyl group and the amino group at position 6 is substituted by an (E)-4-(piperidin-1-yl)but-2-enoyl group.	4.04	3	0	enamide; monochlorobenzenes; monofluorobenzenes; piperidines; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist
azd2932 AZD2932: structure in first source	2.21	1	0
ridaforolimus [no description available]	2.15	1	0	macrolide lactam
dorsomorphin dorsomorphin: an AMPK inhibitor. dorsomorphin : A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine which is substituted at positions 3 and 6 by pyridin-4-yl and p-[2-(piperidin-1-yl)ethoxy]phenyl groups, respectively. It is a potent, selective, reversible, and ATP-competitive inhibitor of AMPK (AMP-activated protein kinase, EC 2.7.11.31) and a selective inhibitor of bone morphogenetic protein (BMP) signaling.	2.08	1	0	aromatic ether; piperidines; pyrazolopyrimidine; pyridines	bone morphogenetic protein receptor antagonist; EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} inhibitor
ac 261066 [no description available]	2.08	1	0
ch 4987655 [no description available]	2.15	1	0
6-(5-((cyclopropylamino)carbonyl)-3-fluoro-2-methylphenyl)-n-(2,2-dimethylprpyl)-3-pyridinecarboxamide [no description available]	2.15	1	0	phenylpyridine
carfilzomib [no description available]	3.07	4	0	epoxide; morpholines; tetrapeptide	antineoplastic agent; proteasome inhibitor
gw9508 GW9508: structure in first source	2.08	1	0	aromatic amine
cc-930 [no description available]	2.15	1	0
jnj 26854165 [no description available]	2.08	1	0
pf 573228 6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one: structure in first source	2.08	1	0	quinolines
gw 2580 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine: a cFMS kinase inhibitor; structure in first source	2.08	1	0
tak 285 N-(2-(4-((3-chloro-4-(3-(trifluoromethyl)phenoxy)phenyl)amino)-5H-pyrrolo(3,2-d)pyrimidin-5-yl)ethyl)-3-hydroxy-3-methylbutanamide: also inhibits HER2; structure in first source	2.15	1	0
idelalisib idelalisib: an antineoplastic agent and p110delta inhibitor; structure in first source. idelalisib : A member of the class of quinazolines that is 5-fluoro-3-phenylquinazolin-4-one in which the hydrogen at position 2 is replaced by a (1S)-1-(3H-purin-6-ylamino)propyl group. used for for the treatment of refractory indolent non-Hodgkin's lymphoma and relapsed chronic lymphocytic leukemia.	3.25	5	0	aromatic amine; organofluorine compound; purines; quinazolines; secondary amino compound	antineoplastic agent; apoptosis inducer; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
crizotinib Crizotinib: A piperidine and aminopyridine derivative that acts as an inhibitor of RECEPTOR PROTEIN-TYROSINE KINASES, including ANAPLASTIC LYMPHOMA KINASE (ALK) and HEPATOCYTE GROWTH FACTOR RECEPTOR (HGFR; c-Met). It is used in the treatment of NON-SMALL CELL LUNG CANCER.. crizotinib : A 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine that has R configuration at the chiral centre. The active enantiomer, it acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)	9.19	31	1	3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine	antineoplastic agent; biomarker; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(2-methylsulfonylphenyl)methoxy]-2-thiophenecarbonitrile [no description available]	2.08	1	0	benzimidazoles
4-[2-(2-chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide Vx-11e: ERK1-2 inhibitor	2.08	1	0	aromatic amide; heteroarene
osi 906 [no description available]	2.81	3	0	cyclobutanes; quinolines
zstk474 ZSTK-474 : A triamino-1,3,5-triazine that is 1,3,5-triazine in which two of the hydrogens have been replaced by morpholin-4-yl groups while the third hydrogen has been replaced by a 2-(difluoromethyl)benzimidazol-1-yl group. It is an inhibitor of phosphatidylinositol 3-kinase.	7.17	1	0	benzimidazoles; morpholines; organofluorine compound; triamino-1,3,5-triazine	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
ly2109761 [no description available]	2.08	1	0
chir-265 [no description available]	2.8	3	0	aromatic ether
motesanib [no description available]	3.4	6	0	pyridinecarboxamide
fostamatinib fostamatinib: a spleen tyrosine kinase (Syk) inhibitor, metabolized to R406	2.15	1	0
az-628 AZ-628: a multikinase inhibitor; structure in first source	2.08	1	0	benzamides
trametinib [no description available]	7.86	3	0	acetamides; aromatic amine; cyclopropanes; organofluorine compound; organoiodine compound; pyridopyrimidine; ring assembly	anticoronaviral agent; antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector
mln8054 [no description available]	2.15	1	0	benzazepine
pf-562,271 [no description available]	3.25	5	0	indoles
gliocladin c gliocladin C: structure in first source	2.89	3	0
sb 706504 [no description available]	2.89	3	0
jnj-26483327 JNJ-26483327: an orally active macrocyclic tyrosine kinase inhibitor for treatment of patients with advanced solid tumours; in Phase I trial, 9/2010	2.15	1	0
ly2603618 [no description available]	2.15	1	0	ureas
veliparib [no description available]	2.08	1	0	benzimidazoles	EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
ku-0060648 [no description available]	3.07	4	0	dibenzothiophenes
tg100801 [no description available]	2.15	1	0
dactolisib dactolisib: antineoplastic agent that inhibits both phosphatidylinositol 3-kinase and mTOR. dactolisib : An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment.	2.81	3	0	imidazoquinoline; nitrile; quinolines; ring assembly; ureas	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor
bgt226 BGT226 free base : An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 3-trifluoromethyl-4-(piperazin-1-yl)phenyl group and at position 8 by a 6-methoxypyridin-3-yl group. A dual PI3K/mTOR inhibitor.. BGT226 : The maleate salt of 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one. A dual PI3K/mTOR inhibitor.	3.27	5	0	aromatic ether; imidazoquinoline; N-arylpiperazine; organofluorine compound; pyridines	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor
palomid 529 [no description available]	2.08	1	0
n-desmethyldanofloxacin N-desmethyldanofloxacin: structure given in first source	2.89	3	0
rabeprazole sodium [no description available]	2.15	1	0	organic sodium salt
tosedostat [no description available]	2.08	1	0	carboxylic ester; hydroxamic acid; secondary carboxamide
mdv 3100 [no description available]	9.46	10	1	(trifluoromethyl)benzenes; benzamides; imidazolidinone; monofluorobenzenes; nitrile; thiocarbonyl compound	androgen antagonist; antineoplastic agent
ku 60019 [no description available]	2.08	1	0
gsk 461364 GSK 461364: an antineoplastic agent that inhibits polo-like kinase 1	2.52	2	0	(trifluoromethyl)benzenes
n-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide: a MEK inhibitor; structure in first source	2.08	1	0
azd 1152-hqpa AZD2811: has antineoplastic activity; structure in first source	2.89	3	0	anilide; monofluorobenzenes; primary alcohol; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor
CDN1163 CDN1163: a SERCA2 activator with antidiabetic activity; structure in first source. CDN1163 : A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-isopropoxybenzoic acid with the primary amino group of 2-methylquinolin-8-amine. An allosteric activator of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA).	2.89	3	0	aromatic ether; quinolines; secondary carboxamide	SERCA activator
nvp-tae684 [no description available]	2.49	2	0	piperidines
enmd 2076 ENMD 2076: an antiangiogenic agent with aurora kinase inhibitory and antineoplastic activities	2.57	2	0
4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6-yl)-n-(3-(trifluoromethyl)phenyl)benzamide 4-methyl-3-(2-(2-morpholinoethylamino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamide: structure in first source	2.08	1	0
gsk 269962a [no description available]	3.07	4	0
e 7050 [no description available]	3.93	3	0	aromatic ether
2-amino-8-ethyl-4-methyl-6-(1H-pyrazol-5-yl)-7-pyrido[2,3-d]pyrimidinone [no description available]	2.15	1	0	pyrazolopyridine
tak-901 [no description available]	2.15	1	0
oligonucleotides [no description available]	4.4	3	0
endothelin-1 Endothelin-1: A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)	5.46	2	0
a-83-01 A-83-01: an ALK-5 inhibitor; structure in first source	2.08	1	0
3-[(1-methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one [no description available]	2.08	1	0	indoles
vx-770 ivacaftor: a CFTR potentiator; structure in first source. ivacaftor : An aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis.	2.08	1	0	aromatic amide; monocarboxylic acid amide; phenols; quinolone	CFTR potentiator; orphan drug
gdc-0973 cobimetinib: has antineoplastic activity; structure in first source. cobimetinib : A member of the class of N-acylazetidines obtained by selective formal condensation of the carboxy group of 3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid with the secondary amino group from the azetidine ring of 3-[(2S)-piperidin-2-yl]azetidin-3-ol. An inhibitor of mitogen-activated protein kinase that is used (as its fumarate salt) in combination with vemurafenib for the treatment of patients with unresectable or metastatic melanoma.	2.15	1	0	aromatic amine; difluorobenzene; N-acylazetidine; organoiodine compound; piperidines; secondary amino compound; tertiary alcohol	antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
buparlisib NVP-BKM120: a pan class I PI3 kinase inhibitor with antineoplastic activity; structure in first source	2.52	2	0	aminopyridine; aminopyrimidine; morpholines; organofluorine compound	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
azd 1480 [no description available]	2.52	2	0
azd8330 [no description available]	2.15	1	0	pyridinecarboxamide
pha 848125 N,1,4,4-tetramethyl-8-((4-(4-methylpiperazin-1-yl)phenyl)amino)-4,5-dihydro-1H-pyrazolo(4,3-h)quinazoline-3-carboxamide: a cyclin dependent kinase inhibitor	3.1	4	0
ro5126766 RO5126766: a dual MEK/RAF kinase inhibitor. CH5126766 : A member of the class of coumarins that is 4-methyl-7-[(pyrimidin-2-yl)oxy]coumarin carrying an additional [2-[(methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl substituent at position 3.	2.15	1	0	aryloxypyrimidine; coumarins; organofluorine compound; pyridines; sulfamides	antineoplastic agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
fedratinib fedratinib: a selective small-molecule inhibitor of JAK2	2.52	2	0	sulfonamide
gsk690693 [no description available]	2.81	3	0	1,2,5-oxadiazole; acetylenic compound; aromatic amine; aromatic ether; imidazopyridine; piperidines; primary amino compound; tertiary alcohol	antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor
cnf 2024 [no description available]	2.08	1	0	2-aminopurines; aromatic ether; organochlorine compound; pyridines	antineoplastic agent; Hsp90 inhibitor
ku 0063794 Ku 0063794: an mTOR inhibitor; structure in first source	2.08	1	0	benzyl alcohols; monomethoxybenzene; morpholines; pyridopyrimidine; tertiary amino compound	antineoplastic agent; mTOR inhibitor
14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene 14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene: has antineoplastic activity; also inhibits Fms-like tyrosine kinase-3; structure in first source	2.15	1	0
azd 7545 AZD 7545: an anilide tertiary carbinol; a pyruvate dehydrogenase kinase 2 inhibitor. AZD7545 : A sulfone that is benzene substituted by [4-(dimethylcarbamoyl)phenyl]sulfonyl, chloro and [(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]amino groups at positions 1, 3 and 4, respectively. It is a potent and non-ATP-competitive inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2) with IC50 of 6.4 nM and exhibits glucose-lowering activity. Also inhibits PDHK1 at higher levels (IC50 = 36.8 nM).	2.08	1	0	benzamides; monochlorobenzenes; organofluorine compound; secondary carboxamide; sulfone; tertiary alcohol; tertiary carboxamide	EC 2.7.11.2 - [pyruvate dehydrogenase (acetyl-transferring)] kinase inhibitor; hypoglycemic agent
nvp-bhg712 [no description available]	2.89	3	0	benzamides
azd5438 [no description available]	2.54	2	0	sulfonamide
nutlin-3b [no description available]	2.08	1	0	Nutlin; piperazinone	anticoronaviral agent
zm323881 ZM323881: inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity; structure in first source	2.15	1	0	aromatic ether; benzyl ether; fluorophenol; halophenol; monofluorobenzenes; organic cation; quinazolines; secondary amino compound; substituted aniline	vascular endothelial growth factor receptor antagonist
pf 04217903 [no description available]	4.5	6	0	quinolines
gdc 0941 pictrelisib : A sulfonamide composed of indazole, morpholine, and methylsulfonyl-substituted piperazine rings bound to a thienopyrimidine ring.	2.52	2	0	indazoles; morpholines; piperazines; sulfonamide; thienopyrimidine	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
sm 164 SM 164: a bivalent Smac mimetic with antineoplastic activity; structure in first source	2.08	1	0	benzenes; organic heterobicyclic compound; secondary carboxamide; triazoles	antineoplastic agent; apoptosis inducer; radiosensitizing agent
5-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-1,3-dihydroindol-2-one [no description available]	2.89	3	0	aromatic ketone
icotinib [no description available]	2.15	1	0
ph 797804 PH 797804: an NSAID; structure in first source. PH 797804 : A member of the class of benzamides obtained by formal condensation of the carboxy group of 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1-yl}-4-methylbenzoic acid with the amino group of methylamine.	3.25	5	0	aromatic ether; benzamides; organobromine compound; organofluorine compound; pyridone	anti-inflammatory agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
pha 408 PHA 408: an IKK-2 antagonist; structure in first source	2.08	1	0
gsk 1016790a GSK1016790A : A tertiary carboxamide that is piperazine in which one of the amino groups has undergone condensation with the carboxy group of N-[(2,4-dichlorophenyl)sulfonyl]-L-serine, while the other has undergone condensation with the carboxy group of N-(1-benzothiophen-2-ylcarbonyl)-L-leucine. It is a cell-permeable, potent and selective agonist of the TRPV4 (transient receptor potential vanilloid 4) channel.	2.08	1	0	1-benzothiophenes; aromatic primary alcohol; dichlorobenzene; N-acylpiperazine; sulfonamide; tertiary carboxamide	TRPV4 agonist
kx-01 [no description available]	2.15	1	0
olaparib [no description available]	2.08	1	0	cyclopropanes; monofluorobenzenes; N-acylpiperazine; phthalazines	antineoplastic agent; apoptosis inducer; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
srt1720 [no description available]	3.07	4	0
plx 4720 PLX 4720: a B-Raf(V600E) kinase inhibitor; structure in first source	2.49	2	0	aromatic ketone; difluorobenzene; organochlorine compound; pyrrolopyridine; sulfonamide	antineoplastic agent; B-Raf inhibitor
mk 5108 [no description available]	2.15	1	0	aromatic ether
cx 4945 [no description available]	2.52	2	0
cudc 101 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide: a histone deacetylase inhibitor; structure in first source	2.81	3	0
purfalcamine purfalcamine: a PfCDPK-1 inhibitor; structure in first source	2.89	3	0
amg 458 1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide: a c-met inhibitor; structure in first source	3.23	1	0
arry-614 pexmetinib: inhibits both p38 mitogen-activated protein kinase and Tie2 protein	2.15	1	0
tak 593 TAK 593: structure in first source	2.15	1	0
mln 8237 MLN 8237: an aurora kinase A inhibitor	2.52	2	0	benzazepine
lde225 sonidegib: specific Smoothened/Smo antagonist. sonidegib : A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as its phosphate salt) for treatment of locally advanced basal cell carcinoma.	2.08	1	0	aminopyridine; aromatic ether; benzamides; biphenyls; morpholines; organofluorine compound; tertiary amino compound	antineoplastic agent; Hedgehog signaling pathway inhibitor; SMO receptor antagonist
gdc 0449 HhAntag691: inhibits the hedgehog pathway and ABC transporters; has antineoplastic activity	2.08	1	0	benzamides; monochlorobenzenes; pyridines; sulfone	antineoplastic agent; Hedgehog signaling pathway inhibitor; SMO receptor antagonist; teratogenic agent
sgx 523 [no description available]	3.91	3	0	aryl sulfide; biaryl; pyrazoles; quinolines; triazolopyridazine	c-Met tyrosine kinase inhibitor; nephrotoxic agent
bms 754807 BMS 754807: an IGR-1R kinase inhibitor; structure in first source	3.1	4	0	pyrazoles; pyridines; pyrrolidines; pyrrolotriazine	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
bms 777607 N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide: a Met kinase inhibitor; structure in first source	4.62	7	0	aromatic amide
sgi 1776 SGI 1776: a Pim kinase inhibitor; structure in first source	2.52	2	0	imidazoles
pci 32765 ibrutinib: a Btk protein inhibitor. ibrutinib : A member of the class of acrylamides that is (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine in which the piperidine nitrogen is replaced by an acryloyl group. A selective and covalent inhibitor of the enzyme Bruton's tyrosine kinase, it is used for treatment of B-cell malignancies.	2.82	3	0	acrylamides; aromatic amine; aromatic ether; N-acylpiperidine; pyrazolopyrimidine; tertiary carboxamide	antineoplastic agent; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
ponatinib [no description available]	5.38	9	0	(trifluoromethyl)benzenes; acetylenic compound; benzamides; imidazopyridazine; N-methylpiperazine	antineoplastic agent; tyrosine kinase inhibitor
amg 900 N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine: a pan-aurora kinase inhibitor; structure in first source	2.52	2	0
mk-1775 adavosertib: a Wee1 kinase inhibitor; structure in first source	2.52	2	0	piperazines
AMG-208 [no description available]	3.64	2	0	aromatic ether; quinolines; triazolopyridazine	antineoplastic agent; c-Met tyrosine kinase inhibitor
bag956 BAG956: an imidazo[4,5-c]quinoline; dual PI3K/PDK-1 inhibitor, used in antileukemic therapies	2.08	1	0
quizartinib [no description available]	3.41	6	0	benzoimidazothiazole; isoxazoles; morpholines; phenylureas	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; necroptosis inhibitor
PP121 [no description available]	2.89	3	0	aromatic amine; cyclopentanes; pyrazolopyrimidine; pyrrolopyridine	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; tyrosine kinase inhibitor
at13148 [no description available]	2.15	1	0
N-[4-[3-[[[7-(hydroxyamino)-7-oxoheptyl]amino]-oxomethyl]-5-isoxazolyl]phenyl]carbamic acid tert-butyl ester CAY10603: a HDAC6 inhibitor	2.08	1	0	carbamate ester
tak 733 [no description available]	2.52	2	0
mk 2206 MK 2206: a protein kinase inhibitor and antineoplastic agent	2.52	2	0	organic heterotricyclic compound	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
navitoclax [no description available]	3.07	4	0	aryl sulfide; monochlorobenzenes; morpholines; N-sulfonylcarboxamide; organofluorine compound; piperazines; secondary amino compound; sulfone; tertiary amino compound	antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor
sns 314 SNS 314: an aurora kinase inhibitor; structure in first source	2.52	2	0	ureas
jzl 184 JZL 184: inhibits monoacylglycerol lipase; structure in first source	2.08	1	0	benzodioxoles
gsk 650394 [no description available]	2.89	3	0	phenylpyridine
lucitanib E-3810: a multi-kinase inhibitor with antineoplastic activity; structure in first source. E-3810 : A hydrochloride salt obtained by reaction of 6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-N-methyl-1-naphthamide with one equivalent of hydrochloric acid. E-3810 is a dual VEGFR and FGFR inhibitor. E-3810 free base : A naphthalenecarboxamide obtained from formal condensation of the carboxy group of aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-1-naphthoic acid with methylamine.	2.15	1	0	aromatic ether; cyclopropanes; naphthalenecarboxamide; primary amino compound; quinolines	antineoplastic agent; fibroblast growth factor receptor antagonist; vascular endothelial growth factor receptor antagonist
pf-04691502 [no description available]	2.15	1	0
n-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide: a Janus kinase 1 and Janus kinase 2 inhibitor; structure in first source. momelotinib : A benzamide obtained by formal condensation of the carboxy group of 4-{2-[4-(morpholin-4-yl)anilino]pyrimidin-4-yl}benzoic acid with the primary amino group of aminoacetonitrile. It is an ATP-competitive JAK1/JAK2 inhibitor with IC50 of 11 nM and 18 nM, respectively. Used for the treatment of patients with intermediate- or high-risk myelofibrosis.	2.81	3	0	aminopyrimidine; benzamides; morpholines; nitrile; secondary amino compound; tertiary amino compound	anti-anaemic agent; antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
dcc-2036 rebastinib: an inhibitor of Tie2 tyrosine kinase receptor and antineoplastic agent	3.25	5	0	organofluorine compound; phenylureas; pyrazoles; pyridinecarboxamide; quinolines	tyrosine kinase inhibitor
defactinib [no description available]	2.15	1	0
ly2584702 [no description available]	2.15	1	0
N-(2,6-difluorophenyl)-5-[3-[2-[5-ethyl-2-methoxy-4-[4-(4-methylsulfonyl-1-piperazinyl)-1-piperidinyl]anilino]-4-pyrimidinyl]-2-imidazo[1,2-a]pyridinyl]-2-methoxybenzamide [no description available]	2.08	1	0	benzamides
incb-018424 [no description available]	2.86	3	0	nitrile; pyrazoles; pyrrolopyrimidine	antineoplastic agent; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
poziotinib HM781-36B: antitumor irreversible Pan-HER inhibitor for treatment of gastric cancer	2.15	1	0	acrylamides; aromatic ether; dichlorobenzene; diether; monofluorobenzenes; N-acylpiperidine; quinazolines; secondary amino compound; substituted aniline	antineoplastic agent; apoptosis inducer; epidermal growth factor receptor antagonist
asp3026 ASP3026: an anaplastic lymphoma receptor tyrosine kinase inhibitor; structure in first source. ASP-3026 : A member of the class of diamino-1,3,5-triazines that is 1,3,5-triazine-2,4-diamine in which the amino groups at positions 2 and 4 are respectively carrying 2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl and 2-(propan-2-ylsulfonyl)phenyl substituents. It is a potent inhibitor of anaplastic lymphoma kinase (ALK), Ack and ROS1 activity (IC50 values are 3.5, 5.8 and 8.9 nM respectively) and exhibits anti-cancer properties.	2.15	1	0	aromatic amine; diamino-1,3,5-triazine; monomethoxybenzene; N-methylpiperazine; piperidines; secondary amino compound; sulfone	antimalarial; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; EC 6.1.1.6 (lysine--tRNA ligase) inhibitor
entrectinib entrectinib: inhibits TRK, ROS1, and ALK receptor tyrosine kinases; structure in first source. entrectinib : A member of the class of indazoles that is 1H-indazole substituted by [4-(4-methylpiperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)benzoyl]amino and 3,5-difluorobenzyl groups at positions 3 and 5, respectively. It is a potent inhibitor of TRKA, TRKB, TRKC, ROS1, and ALK (IC50 values of 0.1 to 1.7 nM), and used for the treatment of NTRK, ROS1 and ALK gene fusion-positive solid tumours.	8.98	3	0	benzamides; difluorobenzene; indazoles; N-methylpiperazine; oxanes; secondary amino compound; secondary carboxamide	antibacterial agent; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
bix 01294 [no description available]	2.08	1	0	piperidines
pexidartinib pexidartinib: inhibits both CSF1R and c-kit receptor tyrosine kinase; structure in first source. pexidartinib : A pyrrolopyridine that is 5-chloro-1H-pyrrolo[2,3-b]pyridine which is substituted by a [6-({[6-(trifluoromethyl)pyridin-3-yl]methyl}amino)pyridin-3-yl]methyl group at position 3. It is a potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, KIT, and FLT3 (IC50 of 20 nM, 10 nM and 160 nM, respectively). Approved by the FDA for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT).	3.71	2	0	aminopyridine; organochlorine compound; organofluorine compound; pyrrolopyridine; secondary amino compound	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
pf 3845 PF 3845: inhibits fatty acid amide hydrolase	2.08	1	0	piperidines
TAK-580 MLN 2480: brain-penetrant RAF dimer antagonist. TAK-580 : A 1,3-thiazolecarboxamide that is 2-[(1R)-1-aminoethyl]-1,3-thiazole-5-carboxylic acid in which the carboxy group undergoes formal condensation with the amino group of 5-chloro-4-(trifluoromethyl)pyridin-2-amine and in which the amino group undergoes formal condensation with the carboxy group of 6-amino-5-chloropyrimidine-4-carboxylic acid. It is a pan-RAF kinase inhibitor which is currently in clinical development for the treatment of radiographically recurrent or progressive low-grade glioma in children and young adults.	3.1	4	0	1,3-thiazolecarboxamide; aminopyrimidine; chloropyridine; organofluorine compound; pyrimidinecarboxamide; secondary carboxamide	antineoplastic agent; apoptosis inducer; B-Raf inhibitor
gsk 2126458 omipalisib: inhibitor of mTOR protein. omipalisib : A member of the class of quinolines that is quinoline which is substituted by pyridazin-4-yl and 5-[(2,4-difluorobenzene-1-sulfonyl)amino]-6-methoxypyridin-3-yl groups at positions 4 and 6, respectively. It is a highly potent inhibitor of PI3K and mTOR developed by GlaxoSmithKline and was previously in human phase 1 clinical trials for the treatment of idiopathic pulmonary fibrosis and solid tumors.	2.52	2	0	aromatic ether; difluorobenzene; pyridazines; pyridines; quinolines; sulfonamide	anticoronaviral agent; antineoplastic agent; autophagy inducer; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor; radiosensitizing agent
emd1214063 tepotinib: MET inhibitor	3.64	2	0
8-(4-aminophenyl)-2-(4-morpholinyl)-1-benzopyran-4-one [no description available]	2.89	3	0	chromones
ixazomib ixazomib: a proteasome inhibitor with antineoplastic activity; MLN2238 is the biologically active form of MLN9708; structure in first source. ixazomib : A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixazomib citrate, it is used in combination therapy for treatment of multiple myeloma.	2.08	1	0	benzamides; boronic acids; dichlorobenzene; glycine derivative	antineoplastic agent; apoptosis inducer; drug metabolite; orphan drug; proteasome inhibitor
ldn 193189 LDN 193189: inhibits bone morphogenetic protein signaling	2.08	1	0	pyrimidines
pf 3758309 PF 3758309: a PAK4 p21-activated kinase inhibitor; structure in first source	3.1	4	0	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
gdc 0980 [no description available]	2.15	1	0
azd2014 vistusertib: potent and selective dual mTORC1 and mTORC2 inhibitor; structure in first source	2.54	2	0
(5-(2,4-bis((3s)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol: a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity; structure in first source	3.09	4	0	benzyl alcohols; morpholines; pyridopyrimidine; tertiary amino compound	antineoplastic agent; apoptosis inducer; mTOR inhibitor
plx4032 [no description available]	2.81	3	0	aromatic ketone; difluorobenzene; monochlorobenzenes; pyrrolopyridine; sulfonamide	antineoplastic agent; B-Raf inhibitor
(2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol [no description available]	2.08	1	0	biphenyls
gsk 1363089 GSK 1363089: a multikinase inhibitor that acts on Met, RON, Axl, and VEGFR; structure in first source	5.5	18	0	aromatic ether
arry-334543 ARRY-334543: an antagonist of ATP-binding cassette subfamily G member 2 (ABCG2); structure in first source	2.15	1	0
kin-193 [no description available]	2.52	2	0	pyridopyrimidine
mk 2461 [no description available]	3.93	3	0
5-(2-benzofuranyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine [no description available]	2.89	3	0	aryl sulfide; thienopyrimidine
5-(3-methylsulfonylphenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine [no description available]	2.89	3	0	aryl sulfide; thienopyrimidine
5-bromo-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine [no description available]	2.89	3	0	aryl sulfide; thienopyrimidine
bay 869766 [no description available]	2.52	2	0
as 703026 [no description available]	2.15	1	0	pyridinecarboxamide
baricitinib [no description available]	3.1	4	0	azetidines; nitrile; pyrazoles; pyrrolopyrimidine; sulfonamide	anti-inflammatory agent; antirheumatic drug; antiviral agent; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; immunosuppressive agent
nvp bvu972 [no description available]	3.23	1	0
4-[6-[4-(methoxycarbonylamino)phenyl]-4-(4-morpholinyl)-1-pyrazolo[3,4-d]pyrimidinyl]-1-piperidinecarboxylic acid methyl ester WYE-354: an mTOR inhibitor; structure in first source	2.08	1	0	carbamate ester
6-(1,3-benzodioxol-5-yl)-N-methyl-N-(thiophen-2-ylmethyl)-4-quinazolinamine [no description available]	2.89	3	0	quinazolines
piperidines Piperidines: A family of hexahydropyridines.	9.95	36	1
6-[(3-aminophenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone ML-265: a small molecule activator of PKM2	3.07	4	0	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
tas-115 4-(2-fluoro-4-((((2-phenylacetyl)amino)thioxomethyl)amino)phenoxy)-7-methoxy-N-methyl-6-quinolinecarboxamide: inhibits both VEGFR and MET kinase; structure in first source	3.23	1	0
N-[(5-bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide [no description available]	2.89	3	0	hydroxyquinoline
p505-15 [no description available]	2.89	3	0
dabrafenib [no description available]	7.66	2	0	1,3-thiazoles; aminopyrimidine; organofluorine compound; sulfonamide	anticoronaviral agent; antineoplastic agent; B-Raf inhibitor
mrt67307 MRT67307: IKK (IκB(inhibitor of NF-κB (nuclear factor κB)) kinase) family inhibitor; structure in first source	2.89	3	0	aromatic amine
pki 587 gedatolisib: inhibits both phosphatidylinositol 3-kinase and mTOR; structure in first source	2.15	1	0
3-[[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl]aniline [no description available]	2.08	1	0	benzenes; sulfonamide
cp 466722 [no description available]	2.08	1	0	quinazolines
CAY10626 [no description available]	2.08	1	0	ureas
n-(3-fluoro-4-((1-methyl-6-(1h-pyrazol-4-yl)-1h-indazol-5 yl)oxy)phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide merestinib: in phase I clinical trials (2013); structure in first source	2.15	1	0
N-[3-[[5-chloro-2-[4-(4-methyl-1-piperazinyl)anilino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide [no description available]	2.89	3	0	piperazines
thiopental sodium [no description available]	2.55	2	0	organochlorine compound; piperazines; pyrimidines	antineoplastic agent; tyrosine kinase inhibitor
ribociclib ribociclib: inhibits both CDK4 and CDK6	3.27	5	0
1-[3-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanone [no description available]	2.89	3	0	aromatic ketone; thienopyrimidine
mk-8033 1-(3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo(4,5)cyclohepta(1,2-b)pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide: inhibits both Ron and c-Met kinases; structure in first source	2.54	2	0
5-(4-amino-1-propan-2-yl-3-pyrazolo[3,4-d]pyrimidinyl)-1,3-benzoxazol-2-amine sapanisertib: an mTOR inhibitor	2.72	2	0	benzoxazole
pha 793887 [no description available]	3.25	5	0	piperidinecarboxamide
gsk 2334470 GSK 2334470: a PDK1 inhibitor; structure in first source	2.21	1	0	indazoles
sb 1518 [no description available]	3.71	2	0
abemaciclib [no description available]	2.58	2	0
mk-8776 [no description available]	2.15	1	0
nvp-bsk805 [no description available]	2.08	1	0
ml228 probe ML228 probe: structure in first source. ML228 : A member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway.	2.89	3	0	1,2,4-triazines; biphenyls; pyridines; secondary amino compound	hypoxia-inducible factor pathway activator
afuresertib [no description available]	2.15	1	0	amphetamines
xmd 8-92 XMD8-92 : A dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one carrying at C-2 on the pyrimidine ring a [2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino substituent. It is an inhibitor of the BMK1 kinase pathway.	2.08	1	0	pyrimidobenzodiazepine	protein kinase inhibitor
pf-03882845 [no description available]	2.89	3	0
gsk 1070916 GSK 1070916: an antineoplastic agent with aurora B/C kinase inhibitory activity	2.54	2	0	pyrazoles; ring assembly
jq1 compound [no description available]	3.07	4	0	carboxylic ester; organochlorine compound; tert-butyl ester; thienotriazolodiazepine	angiogenesis inhibitor; anti-inflammatory agent; antineoplastic agent; apoptosis inducer; bromodomain-containing protein 4 inhibitor; cardioprotective agent; ferroptosis inducer
jnj38877605 [no description available]	3.91	3	0	quinolines
N-[3-(1,3-benzothiazol-2-yl)-5,6-dihydro-4H-thieno[2,3-c]pyrrol-2-yl]acetamide [no description available]	2.08	1	0	benzothiazoles
dinaciclib [no description available]	2.15	1	0	pyrazolopyrimidine
pf-04620110 PF-04620110: a DGAT1 inhibitor; structure in first source	2.89	3	0
gsk525762a molibresib: mimicks acetylated histones; structure in first source	2.89	3	0	benzodiazepine
gilteritinib gilteritinib: an FLT3/AXL protein tyrosine kinase inhibitor. gilteritinib : A member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation.	3.71	2	0	aromatic amine; monomethoxybenzene; N-methylpiperazine; oxanes; piperidines; primary carboxamide; pyrazines; secondary amino compound	antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
alectinib [no description available]	3.97	3	0	aromatic ketone; morpholines; nitrile; organic heterotetracyclic compound; piperidines	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
glpg0634 [no description available]	2.15	1	0
birinapant birinapant: a Smac mimetic with antineoplastic activity	2.21	1	0	dipeptide
torin 1 torin 1 : A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.	3.07	4	0	N-acylpiperazine; N-arylpiperazine; organofluorine compound; pyridoquinoline; quinolines	antineoplastic agent; mTOR inhibitor
abt-199 venetoclax: A BCL-2 inhibitor with antineoplastic activity that is used in the treatment of CHRONIC LYMPHOCYTIC LEUKEMIA associated with chromosome 17p deletion; structure in first source.. venetoclax : A member of the class of pyrrolopyridines that is a potent inhibitor of the antiapoptotic protein B-cell lymphoma 2. It is used for treamtment of chronic lymphocytic leukemia with 17p deletion.	2.89	3	0	aromatic ether; C-nitro compound; monochlorobenzenes; N-alkylpiperazine; N-arylpiperazine; N-sulfonylcarboxamide; oxanes; pyrrolopyridine	antineoplastic agent; apoptosis inducer; B-cell lymphoma 2 inhibitor
ly2940680 [no description available]	2.08	1	0
1-[4-fluoro-3-(trifluoromethyl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)urea [no description available]	3.07	4	0	ureas
N-(4-methyl-2-pyridinyl)-4-[3-(trifluoromethyl)anilino]-1-piperidinecarbothioamide [no description available]	2.89	3	0	(trifluoromethyl)benzenes
ro 4929097 [no description available]	2.08	1	0	dibenzoazepine; dicarboxylic acid diamide; lactam; organofluorine compound	EC 3.4.23.46 (memapsin 2) inhibitor
ncgc00242364 NCGC00242364: structure in first source	2.89	3	0	quinazolines
gsk4112 GSK4112: a Rev-erbalpha agonist; structure in first source	2.08	1	0
encorafenib encorafenib: a BRAF inhibitor	2.15	1	0
bms-911543 N,N-dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo(4,5-d)pyrrolo(2,3b)pyridine-7-carboxamide: has antineoplastic activity; structure in first source	2.15	1	0
azd4547 [no description available]	2.53	2	0	benzamides; N-arylpiperazine; pyrazoles	fibroblast growth factor receptor antagonist
gsk2141795 GSK2141795: an Akt inhibitor with antineoplastic activity; structure in first source	2.15	1	0
torin 2 torin 2 : A member of the class of pyridoquinolines that is benzo[h][1,6]naphthyridin-2-one carrying additional 3-(trifluoromethyl)phenyl and 6-aminopyridin-3-yl substituents at positions 1 and 9 respectively. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.	2.08	1	0	aminopyridine; organofluorine compound; primary amino compound; pyridoquinoline	antineoplastic agent; mTOR inhibitor
pf-4708671 [no description available]	2.08	1	0
gsk1210151a GSK1210151A: inhibitor of the BET family of proteins; structure in first source	2.89	3	0	imidazoquinoline
azd8186 [no description available]	2.15	1	0
hs-173 [no description available]	2.89	3	0
3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea infigratinib: structure in first source. BGJ-398 : A member of the class of phenylureas that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 2,6-dichloro-3,5-dimethoxyphenyl group, while the hydrogens attached to the other nitrogen are replaced by a methyl group and a 6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl group. It is a potent and selective fibroblast growth factor receptor inhibitor.	2.15	1	0	aminopyrimidine; dichlorobenzene; N-alkylpiperazine; N-arylpiperazine; phenylureas	antineoplastic agent; fibroblast growth factor receptor antagonist
sr1664 [no description available]	2.89	3	0	indolecarboxamide
4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-n-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide 4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide: inhibits phosphopantetheinyl transferase; structure in first source	2.89	3	0
natriuretic peptide, brain Natriuretic Peptide, Brain: A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.	2.21	1	0	polypeptide
heme Heme: The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.. ferroheme : Any iron(II)--porphyrin coordination complex.. ferroheme b : Heme b in which the iron has oxidation state +2.. heme : A heme is any tetrapyrrolic chelate of iron.	2.41	1	0
N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide [no description available]	2.83	3	0	benzamides; N-acylpiperidine
N-[4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide [no description available]	2.59	2	0	aminoquinoline
2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide : A member of the class of quinazolines that is quinazoline substituted by {3-methyl-4-[(6-methylpyridin-3-yl)oxy]phenyl}amino and 3-(2-methoxyacetamido)prop-1-en-1-yl groups at positions 4 and 6, respectively.	2.08	1	0	aromatic ether; methylpyridines; olefinic compound; quinazolines; secondary amino compound; secondary carboxamide; toluenes
belinostat [no description available]	2.08	1	0	olefinic compound
cudc-907 [no description available]	2.89	3	0
dcc-2701 DCC-2701: inhibits c-Met protein, TIE-2 protein, and vascular endothelial growth factor receptor	2.55	2	0
methacycline Methacycline: A broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.. methacycline : A tetracycline that is the 6-methylene analogue of oxytetracycline, obtained by formal dehydration at position 6.	2.21	1	0
ethyl 1-benzyl-3-hydroxy-2(5h)-oxopyrrole-4-carboxylate ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate: RN & structure given in first source	2.08	1	0	carboxylic acid; pyrroline
warfarin Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.	8.55	2	0	benzenes; hydroxycoumarin; methyl ketone
tasquinimod tasquinimod: a lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer; structure in first source	3.58	2	0
methacycline monohydrochloride [no description available]	2.59	2	0
2-[[[4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]-oxomethyl]amino]acetic acid [no description available]	2.89	3	0	quinolines
a 769662 [no description available]	2.08	1	0	biphenyls
agi-5198 AGI-5198: inhibits isocitrate dehydrogenase 1; structure in first source	2.89	3	0
byl719 [no description available]	2.61	2	0	proline derivative
cep-32496 agerafenib: inhibitor of RAF family kinases; structure in first source	4.4	5	0
epz004777 [no description available]	2.89	3	0	N-glycosyl compound
3-[[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-4-pyrimidinyl]amino]propanoic acid [no description available]	2.89	3	0	organonitrogen heterocyclic compound
LimKi 3 LIMKi3: LIMK inhibitor. LimKi 3 : A member of the class of pyrazoles that is 1-(2,6-dichlorophenyl)-1H-pyrazole which is substituted by a difluoromethyl group at position 3 and by a 2-(isobutyrylamino)-1,3-thiazol-5-yl group at position 5. It is a a potent cell-permeable inhibitor of LIM kinase 1 and 2.	2.08	1	0	1,3-thiazoles; dichlorobenzene; organofluorine compound; pyrazoles; secondary carboxamide	LIM kinase inhibitor
1-[4-amino-7-[3-(2-methoxyethylamino)propyl]-5-(4-methylphenyl)-6-pyrrolo[2,3-d]pyrimidinyl]-2-fluoroethanone [no description available]	2.08	1	0	pyrroles
rociletinib rociletinib: inhibits epidermal growth factor receptor tyrosine kinase activity; structure in first source	4.04	3	0
entecavir [no description available]	2.89	3	0	benzamides; N-acylpiperidine
2-[5-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-4-methoxy-2-pyrrolylidene]indole [no description available]	2.08	1	0	dipyrrins
ceritinib ceritinib: an anaplastic lymphoma kinase inhibitor. ceritinib : A member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(piperidin-4-yl)-5-methylphenyl and 2-(isopropylsulfonyl)phenyl substituents. Used for the treatment of ALK-positive metastatic non-small cell lung cancer.	8.96	3	0	aminopyrimidine; aromatic ether; organochlorine compound; piperidines; secondary amino compound; sulfone	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]-2-propenamide [no description available]	2.08	1	0	tryptamines
3-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]-6-(phenylmethylene)piperazine-2,5-dione [no description available]	2.08	1	0	pyrazines
gsk837149a GSK837149A: structure in first source	2.08	1	0
N-[4-(3-chloro-4-fluoroanilino)-7-[[(3S)-3-oxolanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide [no description available]	2.08	1	0	quinazolines
N-[4-(3-chloro-4-fluoroanilino)-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide [no description available]	2.08	1	0	quinazolines
wnt-c59 2-(4-(2-methylpyridin-4-yl)phenyl)-N-(4-(pyridin-3-yl)phenyl)acetamide: a PORCN acyltransferase inhibitor; structure in first source	2.08	1	0
5-[1-(2-hydroxyethyl)-3-pyridin-4-yl-4-pyrazolyl]-2,3-dihydroinden-1-one oxime [no description available]	2.08	1	0	indanes
azd1208 [no description available]	2.15	1	0
gkt137831 setanaxib: NOX4/NOX1 inhibitor; a pyrazolopyridine dione derivative	2.89	3	0
vx-509 [no description available]	3.1	4	0
vx-970 berzosertib: an ATR kinase inhibitor	2.89	3	0	sulfonamide
gs-9973 [no description available]	2.89	3	0
amg 925 AMG-925 : An organic heterotricyclic compound that is 9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidine which is substituted by a [6-(hydroxyacetyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl]nitrilo group at position 2 and by a trans-4-methylcyclohexyl group at position 9. It is a FLT3 and CDK4 dual kinase inhibitor that has antineoplastic activity. Currently under clinical investigation in patients with relapsed or refractory acute myeloid leukemia (AML).	4.23	4	0
debio 1347 CH5183284: a fibroblast growth factor receptor antagonist; structure in first source	2.15	1	0
gne-618 GNE-618: inhibits nicotinamide phosphoribosyl transferase; structure in first source	2.89	3	0
g007-lk G007-LK: potent and specific small-molecule tankyrase inhibitor; structure in first source	3.16	4	0
volitinib [no description available]	3.1	4	0
ML355 ML355: 12-Lipoxygenase inhibitor. ML355 : A sulfonamide resulting from the formal condensation of the amino group of 2-aminobenzothiazole with the sulfo group of 4-[(2-hydroxy-3-methoxybenzyl)amino]benzenesulfonic acid. It is an inhibitor of 12-lipoxygenase, being developed by Veralox Therapeutics for the treatment of heparin-induced thrombocytopenia and thrombosis.	2.89	3	0	benzothiazoles; monomethoxybenzene; phenols; secondary amino compound; substituted aniline; sulfonamide	EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor; platelet aggregation inhibitor
acp-196 acalabrutinib: inhibits Bruton’s tyrosine kinase; has antineoplastic activity. acalabrutinib : A member of the class of imidazopyrazines that is imidazo[1,5-a]pyrazine substituted by 4-(pyridin-2-ylcarbamoyl)phenyl, (2S)-1-(but-2-ynoyl)pyrrolidin-2-yl, and amino groups at positions 1, 3 and 8, respectively. It is an irreversible second-generation Bruton's tyrosine kinase (BTK) inhibitor that is approved by the FDA for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy.	2.89	3	0	aromatic amine; benzamides; imidazopyrazine; pyridines; pyrrolidinecarboxamide; secondary carboxamide; tertiary carboxamide; ynone	antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
gsk343 GSK343: an EZH2 methyltransferase inhibitor. GSK343 : A member of the class of indazoles that is 1-isopropyl-1H-indazole-4-carboxamide in which the nitrogen of the carboxamide group is substituted by a (6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl group and in which the indazole ring is substituted at position 6 by a 2-(4-methylpiperazin-1-yl)pyridin-4-yl group. A highly potent and selective EZH2 inhibitor (IC50 = 4 nM).	2.89	3	0	aminopyridine; indazoles; N-alkylpiperazine; N-arylpiperazine; pyridone; secondary carboxamide	antineoplastic agent; apoptosis inducer; EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor
agi-6780 AGI-6780: inhibits isocitrate dehydrogenases 1 and 2; structure in first source	2.89	3	0
khs101 KHS101: a small molecule accelerates neuronal differentiation in the adult rat	2.89	3	0
osimertinib osimertinib: an EGFR tyrosine kinase inhibitor. osimertinib : A member of the class of aminopyrimidines that is 4-(1-methylindol-3-yl)pyrimidin-2-amine in which one of the amino hydrogens is replaced by a 2-methoxy-4-[2-(dimethylamino)ethyl](methyl)amino-5-acrylamidophenyl group. Used (as the mesylate salt) for treatment of EGFR T790M mutation positive non-small cell lung cancer.	3.16	4	0	acrylamides; aminopyrimidine; biaryl; indoles; monomethoxybenzene; secondary amino compound; secondary carboxamide; substituted aniline; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist
cb-839 [no description available]	3.13	4	0
gsk-j4 GSK-J4: a JMJD3 inhibitor; structure in first source	2.89	3	0	organonitrogen heterocyclic compound
pf-06463922 lorlatinib: inhibits both anaplastic lymphoma kinase and c-ros oncogene 1 (ROS1) protein. lorlatinib : A cyclic ether that is 16,17-dihydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecin-15(10H)-one substituted by methyl groups at positions 2 and 10R, and by cyano, amino and fluoro groups at positions 3, 7 and 12 respectively. It is a small molecule inhibitor of ALK and ROS1 kinase developed by Pfizer for the treatment of ALK-positive non-small cell lung cancer.	3.25	1	0	aminopyridine; aromatic ether; azamacrocycle; benzamides; cyclic ether; monofluorobenzenes; nitrile; organic heterotetracyclic compound; pyrazoles	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
pf-06424439 PF-06424439: an inhibitor of diacylglycerol acyltransferase 2; structure in first source	2.89	3	0
etp-46464 ETP-46464: inhibits ATM and Rad3-related kinase; structure in first source	2.89	3	0
imetelstat [no description available]	4.4	3	0
glutaminase [no description available]	8.68	2	0
cyclin d1 Cyclin D1: Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.	2.13	1	0
onc201 TIC10 compound: a TRAIL-dependent antitumor agent; structure in first source	2.89	3	0
kai407 KAI407: an antimalarial; structure in first source	2.89	3	0
6,7-dimethoxy-2-(pyrrolidin-1-yl)-n-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine 6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine: a SETD8 inhibitor; structure in first source	2.89	3	0
enasidenib [no description available]	2.89	3	0	1,3,5-triazines; aminopyridine; aromatic amine; organofluorine compound; secondary amino compound; tertiary alcohol	antineoplastic agent; EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor
oicr-9429 OICR-9429: antineoplastic; structure in first source	2.89	3	0
lly-507 LLY-507: inhibits methyltransferase SMYD2; structure in first source. LLY-507 : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}[biphenyl]-3-carboxylic acid with the amino group of 3-(pyrrolidin-1-yl)propan-1-amine. It is a potent and selective inhibitor of SMYD2 and inhibits the ability of SMYD2 to methylate p53. It serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes.	2.89	3	0
technetium tc 99m medronate Technetium Tc 99m Medronate: A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of its absorption by a variety of tumors, it is useful for the detection of neoplasms.	2.78	3	0
at 9283 [no description available]	3.1	4	0
otssp167 OTS167: inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity	2.15	1	0
chir 258 [no description available]	2.52	2	0
osi 027 OSI 027: inhibits both mTORC1 and mTORC2; structure in first source	2.81	3	0
hypoxanthine [no description available]	2.89	3	0	nucleobase analogue; oxopurine; purine nucleobase	fundamental metabolite
rifampin Rifampin: A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)	8.5	1	1	cyclic ketal; hydrazone; N-iminopiperazine; N-methylpiperazine; rifamycins; semisynthetic derivative; zwitterion	angiogenesis inhibitor; antiamoebic agent; antineoplastic agent; antitubercular agent; DNA synthesis inhibitor; EC 2.7.7.6 (RNA polymerase) inhibitor; Escherichia coli metabolite; geroprotector; leprostatic drug; neuroprotective agent; pregnane X receptor agonist; protein synthesis inhibitor
clozapine Clozapine: A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent.. clozapine : A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia.	2.89	3	0	benzodiazepine; N-arylpiperazine; N-methylpiperazine; organochlorine compound	adrenergic antagonist; dopaminergic antagonist; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; environmental contaminant; GABA antagonist; histamine antagonist; muscarinic antagonist; second generation antipsychotic; serotonergic antagonist; xenobiotic
dacarbazine (E)-dacarbazine : A dacarbazine in which the N=N double bond adopts a trans-configuration.	3.91	2	1	dacarbazine
hli 373 [no description available]	2.08	1	0
pemetrexed pemetrexed disodium : An organic sodium salt that is the disodium salt of N-{4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT).	2.08	1	0	N-acyl-L-glutamic acid; pyrrolopyrimidine	antimetabolite; antineoplastic agent; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; EC 2.1.1.45 (thymidylate synthase) inhibitor; EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor
1-hydroxyphenazine 1-hydroxyphenazine: a virulence factor of Pseudomonas aeruginosa. 1-hydroxyphenazine : A phenazine carrying a hydroxy substituent at the 1-position.	2.89	3	0	phenazines
sildenafil citrate Sildenafil Citrate: A PHOSPHODIESTERASE TYPE-5 INHIBITOR; VASODILATOR AGENT and UROLOGICAL AGENT that is used in the treatment of ERECTILE DYSFUNCTION and PRIMARY PULMONARY HYPERTENSION.. sildenafil citrate : The citrate salt of sildenafil.	2.54	2	0	citrate salt	EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor; vasodilator agent
aprepitant Aprepitant: A morpholine neurokinin-1 (NK1) receptor antagonist that is used in the management of nausea and vomiting caused by DRUG THERAPY, and for the prevention of POSTOPERATIVE NAUSEA AND VOMITING.. aprepitant : A morpholine-based antiemetic, which is or the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy. Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.	2.08	1	0	(trifluoromethyl)benzenes; cyclic acetal; morpholines; triazoles	antidepressant; antiemetic; neurokinin-1 receptor antagonist; peripheral nervous system drug; substance P receptor antagonist
xav939 XAV939: selectively inhibits beta-catenin-mediated transcription; structure in first source. XAV939 : A thiopyranopyrimidine in which a 7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine skeleton is substituted at C-4 by a hydroxy group and at C-2 by a para-(trifluoromethyl)phenyl group.	2.08	1	0	(trifluoromethyl)benzenes; thiopyranopyrimidine	tankyrase inhibitor
2-carboxyarabinitol 1-phosphate [no description available]	2.08	1	0
ro 24-7429 Ro 24-7429: blocks the action of the HIV tat protein; an analog of Ro 5-3335; Proc Natl Acad Sci U S A 1993 Jul 15;90(14):6395-9	2.89	3	0	benzodiazepine
nintedanib nintedanib : A member of the class of oxindoles that is a kinase inhibitor used (in the form of its ethylsulfonate salt) for the treatment of idiopathic pulmonary fibrosis and cancer.	4.64	7	0
n'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthahydrazide [no description available]	2.89	3	0	catechols; hydrazide; hydrazone; naphthols	EC 3.6.5.5 (dynamin GTPase) inhibitor
ver 52296 luminespib : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-(2,4-dihydroxy-5-isopropylphenyl)-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxylic acid with the amino group of ethylamine.	3.07	4	0	aromatic amide; isoxazoles; monocarboxylic acid amide; morpholines; resorcinols	angiogenesis inhibitor; antineoplastic agent; Hsp90 inhibitor
2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1h-indole-5-carbonitrile 2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1H-indole-5-carbonitrile: structure in first source. AZD1080 : A member of the class of hydroxyindoles that is 1H-indole substituted by hydroxy, 5-(morpholin-4-ylmethyl)pyridin-2-yl, and cyano groups at positions 2, 3 and 5, respectively. It is a potent, brain permeable inhibitor of human GSK3alpha and GSK3beta with Ki of 6.9 nM and 31 nM, respectively. The drug was being developed by AstraZeneca for the treatment of Alzheimer's disease (clinical trial now discontinued).	2.15	1	0	hydroxyindoles; morpholines; nitrile; pyridines; tertiary amino compound	antineoplastic agent; apoptosis inducer; EC 2.7.11.26 (tau-protein kinase) inhibitor; tau aggregation inhibitor
sb-590885 N-{5-[2-{4-[2-(dimethylamino)ethoxy]phenyl}-4-(pyridin-4-yl)-1H-imidazol-5-yl]-2,3-dihydro-1H-inden-1-ylidene}hydroxylamine : A ketoxime that is the oxime of indan-1-one in which the hydrogen at position 5 has been replaced by an imidazol-5-yl group which has itself been substituted at positions 2 and 4 by p-[2-(dimethylamino)ethoxy]phenyl and pyridin-4-yl groups, respectively.	2.08	1	0	aromatic ether; imidazoles; ketoxime; pyridines; tertiary amino compound
rvx 208 apabetalone: a bromodomain and extra-terminal domain protein (BET) inhibitor; prevents interactions between BET proteins and acetyl-lysine residues on histone tails to modify epigenetic regulation	2.89	3	0
bmn 673 talazoparib: inhibits both PARP1 and PARP2; structure in first source	2.89	3	0
pf-477736 PF 00477736: a Chk1 inhibitor; structure in first source. PF-00477736 : A diazepinoindole that is 8-amino-4,5-dihydro-6H-[1,2]diazepino[4,5,6-cd]indol-6-one which is substituted at position 2 by a 1-methylpyrazol-4-yl group and in which the amino group at position 8 has undergone condensation with the carboxy group of (2R)-2-cyclohexylglycine to give the corresponding carboxamide. It is an inhibitor of checkpoint kinase 1 (Chk 1).	2.08	1	0
bay 80-6946 copanlisib: an antineoplastic agent with PI3K inhibitory activity; structure in first source. copanlisib : An imidazoquinazoline that is 2,3-dihydroimidazo[1,2-c]quinazoline substituted by (2-aminopyrimidine-5-carbonyl)amino, methoxy, and 3-(morpholin-4-yl)propoxy groups at positions 5, 7 and 8, respectively. It is a intravenous pan-class I PI3K inhibitor used for the treatment of relapsed follicular lymphoma in patients who have received at least 2 prior systemic therapies.	2.15	1	0
fenobam fenobam: in USAN fenobam refers to monohydrate	2.08	1	0	ureas

Condition	Indicated	Relationship Strength	Studies	Trials
Metastase [description not available]	0	19.18	104	63
Benign Neoplasms [description not available]	0	11.33	43	1
Angiogenesis, Pathologic [description not available]	0	7.46	18	0
Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.	0	19.18	104	63
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	1	15.85	86	2
Carcinoma, Non-Small Cell Lung [description not available]	0	12.1	29	8
Cancer of Lung [description not available]	0	14.6	55	17
Carcinoma, Non-Small-Cell Lung A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.	1	14.1	29	8
Lung Neoplasms Tumors or cancer of the LUNG.	0	14.6	55	17
Cancer of the Thyroid [description not available]	0	18.78	108	46
Thyroid Neoplasms Tumors or cancer of the THYROID GLAND.	1	23.53	216	92
Cancer of Ovary [description not available]	0	8.85	9	6
Ovarian Neoplasms Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.	0	8.85	9	6
Breast Cancer [description not available]	0	7.44	6	3
Breast Neoplasms Tumors or cancer of the human BREAST.	1	9.44	6	3
Adenocarcinoma Of Kidney [description not available]	0	23.62	384	148
Cancer of Kidney [description not available]	0	23.49	373	145
Carcinoma, Renal Cell A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.	1	32.04	1,920	740
Kidney Neoplasms Tumors or cancers of the KIDNEY.	1	25.49	373	145
Experimental Neoplasms [description not available]	0	2.91	3	0
Acute Myelogenous Leukemia [description not available]	0	4.62	8	0
Leukemia, Myeloid, Acute Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.	1	6.62	8	0
Hepatocellular Carcinoma [description not available]	0	19.8	123	42
Cancer of Liver [description not available]	0	19.79	125	41
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.	1	21.8	123	42
Liver Neoplasms Tumors or cancer of the LIVER.	0	19.79	125	41
Colorectal Cancer [description not available]	0	7.52	9	3
Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.	1	9.52	9	3
Astrocytoma, Grade IV [description not available]	0	9.35	11	7
Glioblastoma A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.	1	11.35	11	7
Congenital Zika Syndrome [description not available]	0	2.58	2	0
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	0	6.89	21	1
Zika Virus Infection A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME.	0	2.58	2	0
ER-Negative PR-Negative HER2-Negative Breast Cancer [description not available]	0	4.49	4	1
Triple Negative Breast Neoplasms Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN.	0	4.49	4	1
Bone Cancer [description not available]	0	13.26	39	7
Osteogenic Sarcoma [description not available]	0	6.56	5	1
Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES.	0	13.26	39	7
Osteosarcoma A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)	1	8.56	5	1
Complication, Postoperative [description not available]	0	2.57	2	0
Colicky Pain [description not available]	0	2.31	1	0
Local Neoplasm Recurrence [description not available]	0	11.95	18	9
Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	0	2.57	2	0
Abdominal Pain Sensation of discomfort, distress, or agony in the abdominal region.	0	2.31	1	0
Cancer of Cervix [description not available]	0	4.62	1	1
Uterine Cervical Neoplasms Tumors or cancer of the UTERINE CERVIX.	1	6.62	1	1
Adrenal Gland Hypofunction [description not available]	0	2.31	1	0
Adrenal Insufficiency Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.	0	2.31	1	0
Familial Nonmedullary Thyroid Cancer [description not available]	0	2.31	1	0
Carcinoma, Medullary A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)	1	9.63	8	1
Carcinogenesis The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.	0	2.91	3	0
Peritoneal Carcinomatosis [description not available]	0	6.03	4	2
Peritoneal Neoplasms Tumors or cancer of the PERITONEUM.	0	6.03	4	2
Benign Neoplasms, Brain [description not available]	0	9.48	17	3
Brain Neoplasms Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.	0	9.48	17	3
Sarcoma, Epithelioid [description not available]	0	6.33	6	2
Sarcoma A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.	1	8.33	6	2
Disease Exacerbation [description not available]	0	15.64	46	23
Innate Inflammatory Response [description not available]	0	2.31	1	0
Alveolitis, Fibrosing [description not available]	0	2.31	1	0
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	0	7.31	1	0
Pulmonary Fibrosis A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.	0	7.31	1	0
Bladder Cancer [description not available]	0	10.34	11	3
Urinary Bladder Neoplasms Tumors or cancer of the URINARY BLADDER.	1	16.41	33	9
Carcinoma, Transitional Cell A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.	0	10.54	11	3
Carcinoma, Neuroendocrine A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round blue cells, granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small (oat) cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)	1	19.53	76	38
Malignant Melanoma [description not available]	0	4.24	3	1
Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)	1	8.07	9	3
Allergic Cutaneous Angiitis [description not available]	0	3.07	3	0
Ulcer A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.	0	7.41	1	0
Cancer of Salivary Gland [description not available]	0	4.72	1	1
Salivary Gland Neoplasms Tumors or cancer of the SALIVARY GLANDS.	1	6.72	1	1
Blood Pressure, High [description not available]	0	9.77	9	4
Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.	0	9.77	9	4
Mucositis An INFLAMMATION of the MUCOSA with burning or tingling sensation. It is characterized by atrophy of the squamous EPITHELIUM, vascular damage, inflammatory infiltration, and ulceration. It usually occurs at the mucous lining of the MOUTH, the GASTROINTESTINAL TRACT or the airway due to chemical irritations, CHEMOTHERAPY, or radiation therapy (RADIOTHERAPY).	0	2.41	1	0
Diseases of Endocrine System [description not available]	0	3.33	1	0
Exanthem [description not available]	0	3.33	1	0
Lassitude [description not available]	0	10.68	12	4
Cholera Infantum [description not available]	0	3.33	1	0
Diarrhea An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.	0	8.93	7	4
Endocrine System Diseases Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.	0	3.33	1	0
Exanthema Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.	0	3.33	1	0
Fatigue The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.	0	10.68	12	4
Adenocarcinoma, Basal Cell [description not available]	0	12.27	24	14
Androgen-Independent Prostatic Cancer [description not available]	0	13.63	30	15
Adenocarcinoma A malignant epithelial tumor with a glandular organization.	0	12.27	24	14
Prostatic Neoplasms, Castration-Resistant Tumors or cancer of the PROSTATE which can grow in the presence of low or residual amount of androgen hormones such as TESTOSTERONE.	1	15.63	30	15
Liver Steatosis [description not available]	0	2.41	1	0
Fatty Liver Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.	0	2.41	1	0
Choked Disk [description not available]	0	2.6	1	0
Papilledema Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)	0	2.6	1	0
Left Ventricular Dysfunction [description not available]	0	2.96	3	0
Cardiac Failure [description not available]	0	2.72	2	0
Heart Failure A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.	0	2.72	2	0
Ventricular Dysfunction, Left A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.	0	2.96	3	0
Cancer of Colon [description not available]	0	5.34	3	1
Cancer of Rectum [description not available]	0	4.72	1	1
Colonic Neoplasms Tumors or cancer of the COLON.	0	5.34	3	1
Rectal Neoplasms Tumors or cancer of the RECTUM.	1	6.72	1	1
Cancer of Stomach [description not available]	0	4.74	5	1
Ascites Accumulation or retention of free fluid within the peritoneal cavity.	0	2.41	1	0
Stomach Neoplasms Tumors or cancer of the STOMACH.	0	4.74	5	1
Thalassemias [description not available]	0	2.41	1	0
Anemia, Cooley's [description not available]	0	2.41	1	0
Thalassemia A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.	0	7.41	1	0
beta-Thalassemia A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.	0	2.41	1	0
Cancer of Endometrium [description not available]	0	6.05	2	2
Endometrial Neoplasms Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.	0	6.05	2	2
Cirrhosis, Liver [description not available]	0	4.72	1	1
Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.	0	4.72	1	1
Diabetic Glomerulosclerosis [description not available]	0	2.41	1	0
Diabetic Nephropathies KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.	0	2.41	1	0
Gastrointestinal Stromal Neoplasm [description not available]	0	7.82	7	2
Gastrointestinal Stromal Tumors All tumors in the GASTROINTESTINAL TRACT arising from mesenchymal cells (MESODERM) except those of smooth muscle cells (LEIOMYOMA) or Schwann cells (SCHWANNOMA).	1	9.82	7	2
Leukoencephalopathy Syndrome, Posterior [description not available]	0	2.41	1	0
Nutritional Disorders [description not available]	0	2.41	1	0
Nutrition Disorders Disorders caused by nutritional imbalance, either overnutrition or undernutrition.	0	2.41	1	0
Leiomyosarcoma, Epithelioid [description not available]	0	2.41	1	0
Cancer of the Uterus [description not available]	0	5.02	2	1
Leiomyosarcoma A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)	0	2.41	1	0
Soft Tissue Neoplasms Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.	0	2.41	1	0
Uterine Neoplasms Tumors or cancer of the UTERUS.	0	5.02	2	1
Pyoderma Gangrenosum An idiopathic, rapidly evolving, and severely debilitating disease occurring most commonly in association with chronic ulcerative colitis. It is characterized by the presence of boggy, purplish ulcers with undermined borders, appearing mostly on the legs. The majority of cases are in people between 40 and 60 years old. Its etiology is unknown.	0	2.9	2	0
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	0	2.57	2	0
Sarcopenia Progressive decline in muscle mass due to aging which results in decreased functional capacity of muscles.	0	2.41	1	0
Adrenal Cancer [description not available]	0	3.51	2	0
Paraganglioma, Gangliocytic [description not available]	0	3.64	2	0
Pheochromocytoma, Extra-Adrenal [description not available]	0	3.33	1	0
Paraganglioma A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)	0	8.64	2	0
Pheochromocytoma A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)	0	3.33	1	0
Ewing Sarcoma [description not available]	0	6.53	5	1
Sarcoma, Ewing A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. The tumor occurs usually before the age of 20, about twice as frequently in males as in females.	0	6.53	5	1
Carcinoma, Squamous Cell of Head and Neck [description not available]	0	5.41	3	1
Carcinoma, Anaplastic [description not available]	0	10.3	12	5
Cancer of Head [description not available]	0	5.52	3	1
Squamous Cell Carcinoma of Head and Neck The most common type of head and neck carcinoma that originates from cells on the surface of the NASAL CAVITY; MOUTH; PARANASAL SINUSES, SALIVARY GLANDS, and LARYNX. Mutations in TNFRSF10B, PTEN, and ING1 genes are associated with this cancer.	0	5.41	3	1
Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.	1	12.3	12	5
Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)	0	5.52	3	1
Bleeding [description not available]	0	4.21	11	0
Nail Diseases Diseases of the nail plate and tissues surrounding it. The concept is limited to primates.	0	2.57	2	0
Dermatoses [description not available]	0	2.41	1	0
Hemorrhage Bleeding or escape of blood from a vessel.	0	4.21	11	0
Skin Diseases Diseases involving the DERMIS or EPIDERMIS.	0	2.41	1	0
Autoimmune Diabetes [description not available]	0	2.6	1	0
Diabetes Mellitus, Type 1 A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.	0	2.6	1	0
Thromboembolism, Venous [description not available]	0	4.21	9	0
Venous Thromboembolism Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream.	0	4.21	9	0
Uveal Neoplasms Tumors or cancer of the UVEA.	0	4.8	5	1
Thyroid Cancer, Anaplastic [description not available]	0	3.97	2	0
Thyroid Carcinoma, Anaplastic An aggressive THYROID GLAND malignancy which generally occurs in IODINE-deficient areas in people with previous thyroid pathology such as GOITER. It is associated with CELL DEDIFFERENTIATION of THYROID CARCINOMA (e.g., FOLLICULAR THYROID CARCINOMA; PAPILLARY THYROID CANCER). Typical initial presentation is a rapidly growing neck mass which upon metastasis is associated with DYSPHAGIA; NECK PAIN; bone pain; DYSPNEA; and NEUROLOGIC DEFICITS.	0	3.97	2	0
Rhabdomyolysis Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.	0	7.6	1	0
Degenerative Diseases, Central Nervous System [description not available]	0	2.6	1	0
Acute Confusional Senile Dementia [description not available]	0	2.6	1	0
Alzheimer Disease A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)	0	2.6	1	0
Neurodegenerative Diseases Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.	0	2.6	1	0
Thoracic Neoplasms New abnormal growth of tissue in the THORAX.	0	3.99	1	1
Neuroendocrine Tumors Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.	1	7.8	10	2
Anoxemia [description not available]	0	2.63	2	0
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms.	0	7.63	2	0
Carcinoma, Epidermoid [description not available]	0	2.72	2	0
Adenocarcinoma, Papillary An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)	0	2.6	1	0
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	1	4.72	2	0
Genito-urinary Cancer [description not available]	0	6.68	3	2
Urogenital Neoplasms Tumors or cancer of the UROGENITAL SYSTEM in either the male or the female.	1	8.68	3	2
Chemotherapy-Induced Acral Erythema [description not available]	0	3.74	3	0
Hand-Foot Syndrome Chemotherapy-induced dermal side effects that are associated with the use of various CYTOSTATIC AGENTS. Symptoms range from mild ERYTHEMA and/or PARESTHESIA to severe ulcerative dermatitis with debilitating pain involving typically palmoplantar and intertriginous areas. These cutaneous manifestations are sometimes accompanied by nail anomalies.	0	3.74	3	0
Adrenocortical Carcinoma A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM.	0	5.31	5	0
Adrenal Cortex Cancer [description not available]	0	5.61	6	0
Adrenal Cortex Neoplasms Tumors or cancers of the ADRENAL CORTEX.	1	7.61	6	0
Cardiac Cancer [description not available]	0	2.25	1	0
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	0	2.83	3	0
Carcinosarcoma A malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. (Stedman, 25th ed)	0	4.55	1	1
Anastomotic Leak Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis.	0	7.25	1	0
Spinal Neoplasms New abnormal growth of tissue in the SPINE.	0	2.25	1	0
Response Evaluation Criteria in Solid Tumors An internationally recognized set of published rules used for evaluation of cancer treatment that define when tumors found in cancer patients improve, worsen, or remain stable during treatment. These criteria are based specifically on the response of the tumor(s) to treatment, and not on the overall health status of the patient resulting from treatment.	0	5.99	2	2
Cyst [description not available]	0	2.25	1	0
Liver Dysfunction [description not available]	0	2.58	2	0
Liver Diseases Pathological processes of the LIVER.	1	4.58	2	0
Osteolysis Dissolution of bone that particularly involves the removal or loss of calcium.	0	2.85	3	0
Neuroblastoma A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)	0	4.46	4	1
Proteinuria The presence of proteins in the urine, an indicator of KIDNEY DISEASES.	0	7.31	1	0
Corneal Angiogenesis [description not available]	0	2.25	1	0
Corneal Neovascularization New blood vessels originating from the corneal blood vessels and extending from the limbus into the adjacent CORNEAL STROMA. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as TRACHOMA, viral interstitial KERATITIS, microbial KERATOCONJUNCTIVITIS, and the immune response elicited by CORNEAL TRANSPLANTATION.	0	7.25	1	0
Cancer of Gastrointestinal Tract [description not available]	0	5.14	3	1
Endometrial Stromal Sarcoma [description not available]	0	4.55	1	1
Sarcoma, Endometrial Stromal A highly malignant subset of neoplasms arising from the endometrial stroma. Tumors in this group infiltrate the stroma with a wide range of atypia cells and numerous mitoses. They are capable of widespread metastases (NEOPLASM METASTASIS).	0	4.55	1	1
Cancer of the Urinary Tract [description not available]	0	7.33	4	2
Lung Adenocarcinoma [description not available]	0	11.44	19	9
Adenocarcinoma of Lung A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.	0	11.44	19	9
Bisphosphonate Osteonecrosis [description not available]	0	2.31	1	0
Aseptic Necrosis of Bone [description not available]	0	2.9	3	0
Osteonecrosis Death of a bone or part of a bone, either atraumatic or posttraumatic.	0	2.9	3	0
Cells, Neoplasm Circulating [description not available]	0	8.9	7	6
Colitis Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.	0	4.55	1	1
Hepatitis INFLAMMATION of the LIVER.	0	4.55	1	1
Hand Dermatosis [description not available]	0	2.25	1	0
Foot Dermatoses Skin diseases of the foot, general or unspecified.	0	2.25	1	0
Hand Dermatoses Skin diseases involving the HANDS.	0	2.25	1	0
Fibrosarcoma A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)	0	2.25	1	0
Experimental Hepatoma [description not available]	0	2.31	1	0
Pyrexia [description not available]	0	2.25	1	0
Fever An abnormal elevation of body temperature, usually as a result of a pathologic process.	0	7.25	1	0
Cancer of Prostate [description not available]	0	10.72	23	1
Prostatic Neoplasms Tumors or cancer of the PROSTATE.	1	12.72	23	1
Erythrophagocytic Lymphohistiocytosis, Familial [description not available]	0	2.31	1	0
Lymphohistiocytosis, Hemophagocytic A group of related disorders characterized by LYMPHOCYTOSIS; HISTIOCYTOSIS; and hemophagocytosis. The two major forms are familial and reactive.	0	2.31	1	0
Dermatitis Medicamentosa [description not available]	0	5.18	3	1
Cafe-au-Lait Spots with Pulmonic Stenosis [description not available]	0	4.62	1	1
Elephantiasis Neuromatosis [description not available]	0	4.62	1	1
Neurofibromatosis 1 An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).	0	4.62	1	1
Neurofibroma, Plexiform A type of neurofibroma manifesting as a diffuse overgrowth of subcutaneous tissue, usually involving the face, scalp, neck, and chest but occasionally occurring in the abdomen or pelvis. The tumors tend to progress, and may extend along nerve roots to eventually involve the spinal roots and spinal cord. This process is almost always a manifestation of NEUROFIBROMATOSIS 1. (From Adams et al., Principles of Neurology, 6th ed, p1016; J Pediatr 1997 Nov;131(5):678-82)	0	4.62	1	1
Ache [description not available]	0	5.7	3	2
Pain An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.	0	5.7	3	2
Benign Meningeal Neoplasms [description not available]	0	2.31	1	0
Angioblastic Meningioma [description not available]	0	2.31	1	0
Meningeal Neoplasms Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.	0	2.31	1	0
Meningioma A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)	1	9.31	1	0
Di Guglielmo Disease [description not available]	0	2.41	1	0
Leukemia, Erythroblastic, Acute A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.	0	2.41	1	0
Neoplasms, Skull Base [description not available]	0	2.31	1	0
Chordoma A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed)	0	2.31	1	0
Adverse Drug Event [description not available]	0	8.14	7	3
Drug-Related Side Effects and Adverse Reactions Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.	0	8.14	7	3
MEA 2a [description not available]	0	3.06	1	0
Electrocardiogram QT Prolonged [description not available]	0	3.53	1	1
Electrolytes Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)	0	8.53	1	1
Long QT Syndrome A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.	0	3.53	1	1
Neurilemoma [description not available]	0	2.15	1	0
Neurilemmoma A neoplasm that arises from SCHWANN CELLS of the cranial, peripheral, and autonomic nerves. Clinically, these tumors may present as a cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or with spinal cord compression. Histologically, these tumors are encapsulated, highly vascular, and composed of a homogenous pattern of biphasic fusiform-shaped cells that may have a palisaded appearance. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp964-5)	0	2.15	1	0
Alveolar Soft Part Sarcoma [description not available]	0	7.15	1	0
Sarcoma, Alveolar Soft Part A variety of rare sarcoma having a reticulated fibrous stroma enclosing groups of sarcoma cells, which resemble epithelial cells and are enclosed in alveoli walled with connective tissue. It is a rare tumor, usually occurring between 15 and 35 years of age. It appears in the muscles of the extremities in adults and most commonly in the head and neck regions of children. Though slow-growing, it commonly metastasizes to the lungs, brain, bones, and lymph nodes. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1365)	0	2.15	1	0
Central Nervous System Neoplasm [description not available]	0	2.17	1	0
Central Nervous System Neoplasms Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.	0	2.17	1	0
Adenocarcinoma, Clear Cell An adenocarcinoma characterized by the presence of varying combinations of clear and hobnail-shaped tumor cells. There are three predominant patterns described as tubulocystic, solid, and papillary. These tumors, usually located in the female reproductive organs, have been seen more frequently in young women since 1970 as a result of the association with intrauterine exposure to diethylstilbestrol. (From Holland et al., Cancer Medicine, 3d ed)	0	4.24	3	1
Kidney Diseases Pathological processes of the KIDNEY or its component tissues.	0	2.17	1	0
Thrombotic Microangiopathies Diseases that result in THROMBOSIS in MICROVASCULATURE. The two most prominent diseases are PURPURA, THROMBOTIC THROMBOCYTOPENIC; and HEMOLYTIC-UREMIC SYNDROME. Multiple etiological factors include VASCULAR ENDOTHELIAL CELL damage due to SHIGA TOXIN; FACTOR H deficiency; and aberrant VON WILLEBRAND FACTOR formation.	0	2.17	1	0
Thrombocythemia [description not available]	0	2.17	1	0
Cancer of Skin [description not available]	0	6.13	5	2
Merkel Cell Cancer [description not available]	0	4.88	2	1
Skin Neoplasms Tumors or cancer of the SKIN.	0	6.13	5	2
Carcinoma, Merkel Cell A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)	0	4.88	2	1
Cancer of the Fallopian Tube [description not available]	0	5.46	2	2
Fallopian Tube Neoplasms Benign or malignant neoplasms of the FALLOPIAN TUBES. They are uncommon. If they develop, they may be located in the wall or within the lumen as a growth attached to the wall by a stalk.	0	5.46	2	2
Cramp [description not available]	0	2.17	1	0
Orthopedic Disorders [description not available]	0	2.17	1	0
Muscle Cramp A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398)	0	2.17	1	0
Musculoskeletal Diseases Diseases of the muscles and their associated ligaments and other connective tissue and of the bones and cartilage viewed collectively.	0	2.17	1	0
Cardiac Toxicity [description not available]	0	3.51	2	0
Cardiotoxicity Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.	0	8.51	2	0
Cell Transformation, Neoplastic Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.	0	2.17	1	0
Cancer-Associated Pain [description not available]	0	3.59	1	1
Cancer Pain Pain that may be caused by or related to cellular, tissue, and systemic changes that occur during NEOPLASM growth, tissue invasion, and METASTASIS.	0	3.59	1	1
Epithelial Ovarian Cancer [description not available]	0	4.51	1	1
Carcinoma, Ovarian Epithelial A malignant neoplasm that originates in cells on the surface EPITHELIUM of the ovary and is the most common form of ovarian cancer. There are five histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Mutations in BRCA1, OPCML, PRKN, PIK3CA, AKT1, CTNNB1, RRAS2, and CDH1 genes are associated with this cancer.	0	4.51	1	1
Milk-Alkali Syndrome [description not available]	0	3.09	1	0
Hypercalcemia Abnormally high level of calcium in the blood.	0	3.09	1	0
Central Hypothyroidism [description not available]	0	3.48	2	0
Hypothyroidism A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.	0	8.48	2	0
Acute Liver Injury, Drug-Induced [description not available]	0	3.12	1	0
Chemical and Drug Induced Liver Injury A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.	0	3.12	1	0
Pneumothorax, Primary Spontaneous [description not available]	0	2.21	1	0
Pneumothorax An accumulation of air or gas in the PLEURAL CAVITY, which may occur spontaneously or as a result of trauma or a pathological process. The gas may also be introduced deliberately during PNEUMOTHORAX, ARTIFICIAL.	0	7.21	1	0
Chronic Illness [description not available]	0	2.21	1	0
Rheumatoid Arthritis [description not available]	0	2.21	1	0
Autoimmune Disease [description not available]	0	2.21	1	0
Erythremia [description not available]	0	2.21	1	0
Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.	0	2.21	1	0
Autoimmune Diseases Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.	0	2.21	1	0
Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).	0	2.21	1	0
Myeloproliferative Disorders Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.	0	2.21	1	0
Polycythemia Vera A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.	0	2.21	1	0
Asymptomatic Conditions [description not available]	0	2.21	1	0
Apoplexy [description not available]	0	2.21	1	0
Stroke A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)	0	7.21	1	0
Cardiovascular Stroke [description not available]	0	2.21	1	0
Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).	0	7.21	1	0
Deep Vein Thrombosis [description not available]	0	3.12	1	0
Venous Thrombosis The formation or presence of a blood clot (THROMBUS) within a vein.	0	3.12	1	0
Invasiveness, Neoplasm [description not available]	0	5.09	9	0
Cancer of Pancreas [description not available]	0	5.63	6	1
Carcinoma, Ductal, Pancreatic [description not available]	0	2.08	1	0
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).	1	7.63	6	1
Carcinoma, Pancreatic Ductal Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.	0	2.08	1	0
Osteosclerosis An abnormal hardening or increased density of bone tissue.	0	2.1	1	0
Respiratory Tract Fistula An abnormal passage communicating between any component of the respiratory tract or between any part of the respiratory system and surrounding organs.	0	2.1	1	0
Esophageal Fistula Abnormal passage communicating with the ESOPHAGUS. The most common type is TRACHEOESOPHAGEAL FISTULA between the esophagus and the TRACHEA.	0	2.1	1	0
Esophagotracheal Fistula [description not available]	0	2.1	1	0
Thyroid Diseases Pathological processes involving the THYROID GLAND.	0	3.48	1	1
Thyrotoxicosis A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.	0	3.48	1	1
Bone Loss, Osteoclastic [description not available]	0	2.52	2	0
Fracture, Pathologic [description not available]	0	3.01	1	0
Bone Fractures [description not available]	0	2.1	1	0
Fractures, Bone Breaks in bones.	0	2.1	1	0
Giant Cell Tumor of Bone A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)	0	7.1	1	0
Lymph Node Metastasis [description not available]	0	5.88	3	1
Mandibular Diseases Diseases involving the MANDIBLE.	0	2.11	1	0
Brain Stem Neoplasms, Primary [description not available]	0	2.11	1	0
Glial Cell Tumors [description not available]	0	2.52	2	0
Glioma Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)	0	7.52	2	0
Brain Stem Neoplasms Benign and malignant intra-axial tumors of the MESENCEPHALON; PONS; or MEDULLA OBLONGATA of the BRAIN STEM. Primary and metastatic neoplasms may occur in this location. Clinical features include ATAXIA, cranial neuropathies (see CRANIAL NERVE DISEASES), NAUSEA, hemiparesis (see HEMIPLEGIA), and quadriparesis. Primary brain stem neoplasms are more frequent in children. Histologic subtypes include GLIOMA; HEMANGIOBLASTOMA; GANGLIOGLIOMA; and EPENDYMOMA.	0	2.11	1	0
Kahler Disease [description not available]	0	3.91	2	1
Multiple Myeloma A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.	1	10.91	2	1
Carcinoma, Papillary A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (Stedman, 25th ed)	0	2.11	1	0
Adenoma, Basal Cell [description not available]	0	3.03	1	0
Adenoma A benign epithelial tumor with a glandular organization.	0	3.03	1	0
Ectopic Ossification [description not available]	0	2.11	1	0
Embolism, Pulmonary [description not available]	0	3.04	1	0
Pulmonary Embolism Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.	0	3.04	1	0
Anaplastic Astrocytoma [description not available]	0	3.51	1	1
Colonic Inertia Symptom characterized by the passage of stool once a week or less.	0	3.51	1	1
Leukocytopenia [description not available]	0	3.51	1	1
Thrombopenia [description not available]	0	3.51	1	1
Astrocytoma Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)	1	5.51	1	1
Constipation Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.	0	3.51	1	1
Leukopenia A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).	0	3.51	1	1
Nausea An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.	0	3.51	1	1
Neutropenia A decrease in the number of NEUTROPHILS found in the blood.	0	5.41	2	2
Thrombocytopenia A subnormal level of BLOOD PLATELETS.	0	3.51	1	1
Infections, Listeria [description not available]	0	2.13	1	0
Kidney Failure A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.	0	2.13	1	0
Renal Insufficiency Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.	0	2.13	1	0
Genetic Predisposition [description not available]	0	2.13	1	0
Neoplasms, Nerve Sheath [description not available]	0	2.49	2	0
Nerve Sheath Neoplasms Neoplasms which arise from nerve sheaths formed by SCHWANN CELLS in the PERIPHERAL NERVOUS SYSTEM or by OLIGODENDROCYTES in the CENTRAL NERVOUS SYSTEM. Malignant peripheral nerve sheath tumors, NEUROFIBROMA, and NEURILEMMOMA are relatively common tumors in this category.	0	2.49	2	0
Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.	0	2.13	1	0
Cholangiocellular Carcinoma [description not available]	0	4.45	1	1
Bile Duct Cancer [description not available]	0	4.45	1	1
Nasal Bleeding [description not available]	0	4.45	1	1
Bilirubinemia [description not available]	0	4.45	1	1
Cholecystoduodenal Fistula [description not available]	0	4.45	1	1
Intestinal Perforation Opening or penetration through the wall of the INTESTINES.	0	4.45	1	1
Bile Duct Neoplasms Tumors or cancer of the BILE DUCTS.	0	4.45	1	1
Epistaxis Bleeding from the nose.	0	4.45	1	1
Cholangiocarcinoma A malignant tumor arising from the epithelium of the BILE DUCTS.	1	11.45	1	1
Colitis Gravis [description not available]	0	2.15	1	0
Colitis, Ulcerative Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.	0	2.15	1	0
Island Cell Tumor [description not available]	0	2.06	1	0
Adenoma, Islet Cell A benign tumor of the pancreatic ISLET CELLS. Usually it involves the INSULIN-producing PANCREATIC BETA CELLS, as in INSULINOMA, resulting in HYPERINSULINISM.	0	2.06	1	0
Recrudescence [description not available]	0	2.08	1	0
Abnormalities, Autosome [description not available]	0	2.08	1	0

cabozantinib

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Roles (2)

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Protein Targets (314)

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Molecular Functions (505)

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Studies (721)

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Research Demand Index: 79.97

Study Types

cabozantinib

Description

Cross-References

Synonyms (83)

Research Excerpts

Overview

Effects

Actions

Treatment

Toxicity

Pharmacokinetics

Compound-Compound Interactions

Bioavailability

Dosage Studied

Roles (2)

Drug Classes (4)

Protein Targets (314)

Potency Measurements

Inhibition Measurements

Activation Measurements

Other Measurements

Biological Processes (2585)

Molecular Functions (505)

Ceullar Components (410)

Bioassays (739)

Research

Studies (721)

Market Indicators

Research Demand Index: 79.97

Study Types

Related Drugs (871)

Related Conditions (340)