Compounds > zolpidem carboxylic acid
Page last updated: 2024-11-12

zolpidem carboxylic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

zolpidem carboxylic acid: zolpidem metabolite; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11966044
SCHEMBL ID2309139
MeSH IDM0511684

Synonyms (16)

Synonym
imidazo(1,2-a)pyridine, benzoic acid deriv.
zolpidem carboxylic acid
benzoic acid, 4-(3-(2-(dimethylamino)-2-oxoethyl)-6-methylimidazo(1,2-a)pyridin-2-yl)-
109461-65-6
ogv9r9660k ,
unii-ogv9r9660k
sl 84.0589
4-[3-[2-(dimethylamino)-2-oxoethyl]-6-methylimidazo[1,2-a]pyridin-2-yl]benzoic acid
zolpidem phenyl-4-carboxylic acid
SCHEMBL2309139
DTXSID50148941
zolpidem-m carboxylic acid
BCP10204
Q27285649
A903989
zolpidem phenyl-4-carboxylic acid (1 mg/ml in 1:1 acetonitrile:water)

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Further, while the Food and Drug Administration has pointed out that female dosing should be half that given to males, results of this population testing indicate that the majority of patients (83% male and 73% female) receive 10 mg/day or 12."( Zolpidem and Zolpidem Carboxylic Acid Results from Medication Monitoring.
Cummings, OT; Feng, S; McIntire, G, 2018)		0.85
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's6 (75.00)24.3611
2020's1 (12.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.90

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.90 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index5.35 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.90)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (12.50%)4.05%
Observational0 (0.00%)0.25%
Other7 (87.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
zolpidem
Zolpidem: An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.. zolpidem : An imidazo[1,2-a]pyridine compound having a 4-tolyl group at the 2-position, an N,N-dimethylcarbamoylmethyl group at the 3-position and a methyl substituent at the 6-position.		3.6380imidazopyridinecentral nervous system depressant;
GABA agonist;
sedative
ConditionIndicatedRelationship StrengthStudiesTrials
Aspiration, Respiratory
[description not available]		02.1710
Pain, Chronic
[description not available]		02.110
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.7630
Chronic Pain
Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.		02.110