Compounds > 2,3-dichloro-1-propene
Page last updated: 2024-09-20

2,3-dichloro-1-propene

Description

2,3-dichloro-1-propene: soil fumigant [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6565
CHEMBL ID156075
SCHEMBL ID78819
MeSH IDM0126903

Synonyms (50)

Synonym
1-propene, 2,3-dichloro-
propene, 2,3-dichloro-
2-chloroallyl chloride
wln: g1ygu1
2,3-dichloro-1-propene
nsc60520
nsc-60520
2,3-dichloropropylene
78-88-6
2,3-dichloropropene
NCGC00091735-01
brn 1361491
hsdb 5222
1,2-dichloro-2-propene
ai3-14619
einecs 201-153-8
propylene, 2,3-dichloro
ccris 956
nsc 60520
2,3-dichloro-1-propene, 98%
2,3-dichloroprop-1-ene
D0406
CHEMBL156075
2,3-dichloro-propene
AKOS000121539
A839523
2,3-bis(chloranyl)prop-1-ene
NCGC00091735-02
dtxcid605012
cas-78-88-6
tox21_200640
NCGC00258194-01
dtxsid6025012 ,
ec 201-153-8
370tnk5i41 ,
unii-370tnk5i41
FT-0609537
dichloro-1-propene, 2,3-
2,3-dichloro-1-propene [hsdb]
SCHEMBL78819
1,2-dichloroprop-2-ene
2,3-dichloropropene-(1)
mfcd00000943
J-506935
AMY4111
Q27256607
D97733
2,3-dichloro-prop-1-ene
BS-43822
EN300-21166

Protein Targets (5)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
AR proteinHomo sapiens (human)Potency0.00380.000221.22318,912.5098AID743042
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency19.95260.011212.4002100.0000AID1030
estrogen nuclear receptor alphaHomo sapiens (human)Potency60.90640.000229.305416,493.5996AID743069
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency50.11870.001019.414170.9645AID588537
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency25.50650.000323.4451159.6830AID743065; AID743067
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID384212Mutagenic activity in Salmonella Typhimurium TA100 assessed as logarithm of his+ revertant number increasing activity by amens test2008Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10
Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.
AID19825Partition coefficient (logP)1995Journal of medicinal chemistry, Feb-17, Volume: 38, Issue:4
Molecular similarity matrices and quantitative structure-activity relationships: a case study with methodological implications.
AID37562Induction of aneuploidy in Aspergillus nidulans.1995Journal of medicinal chemistry, Feb-17, Volume: 38, Issue:4
Molecular similarity matrices and quantitative structure-activity relationships: a case study with methodological implications.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (30.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
ethylene dichloride[no description available]medium10chloroethaneshepatotoxic agent;
mutagen;
non-polar solvent
bromoform[no description available]medium10bromohydrocarbon;
bromomethanes
carbon tetrachloride[no description available]medium10chlorocarbon;
chloromethanes		hepatotoxic agent;
refrigerant
chloroform[no description available]medium10chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
hexachloroethane[no description available]medium10chlorocarbon;
chloroethanes		carcinogenic agent;
refrigerant
1,1,1-trichloroethane[no description available]medium10chloroethanespolar solvent
bromoethane[no description available]medium10bromoalkane;
bromohydrocarbon;
volatile organic compound		alkylating agent;
carcinogenic agent;
local anaesthetic;
refrigerant;
solvent
bromochloromethane[no description available]medium10halomethane
methylene chloride[no description available]medium10chloromethanes;
volatile organic compound		carcinogenic agent;
polar aprotic solvent;
refrigerant
bromodichloromethane[no description available]medium10halomethaneenvironmental contaminant;
reagent
1,1-dichloroethane[no description available]medium10organochlorine compound
vinylidene chloride[no description available]medium10chloroethenescarcinogenic agent;
mouse metabolite;
mutagen
bromotrichloromethane[no description available]medium10
trichlorofluoromethane[no description available]medium10chlorofluorocarbon;
halomethane		environmental contaminant;
NMR chemical shift reference compound;
NMR solvent;
refrigerant
pentachloroethane[no description available]medium10chloroethanesnon-polar solvent
propylene dichloride[no description available]medium10chloroalkane;
volatile organic compound
1,1,2-trichloroethane[no description available]medium10chloroethanes
trichloroethylene[no description available]medium20chloroethenesinhalation anaesthetic;
mouse metabolite
1,1,2,2-tetrachloroethane[no description available]medium10chloroethanes
1,2,3-trichloropropane[no description available]medium10organochlorine compound
1-bromo-2-chloroethane[no description available]medium10haloalkane;
organobromine compound;
organochlorine compound		mutagen
butyl bromide[no description available]medium10
butyl chloride[no description available]medium10
1,3-dichloropropane[no description available]medium10chloroalkane;
chlorohydrocarbon		environmental contaminant;
nematicide
1-chloro-2-methylpropene[no description available]medium10organochlorine compound
1-chlorohexane[no description available]medium10
3-chloro-2-methylprop-1-ene[no description available]medium10organochlorine compound
2,2-dichloropropane[no description available]medium10
1,1,1,2-tetrachloroethane[no description available]medium10chloroethanes
chlorodibromomethane[no description available]medium10organochlorine compound
tetrachloroethylene[no description available]medium10chlorocarbon;
chloroethenes		nephrotoxic agent
chloroacetaldehyde[no description available]medium10organochlorine compound
ethylene chlorohydrin[no description available]medium10chloroethanolxenobiotic metabolite
chloroacetic acid[no description available]medium10chlorocarboxylic acid;
haloacetic acid		alkylating agent;
herbicide
iodoacetic acid[no description available]medium10haloacetic acid;
organoiodine compound		alkylating agent
bromoacetate[no description available]medium10
2-bromopropane[no description available]medium10
tribromoacetic acid[no description available]medium10
trichloroacetic acid[no description available]medium10monocarboxylic acid;
organochlorine compound		carcinogenic agent;
metabolite;
mouse metabolite
2,2-dichloroacetyl chloride[no description available]medium10acyl chloridehapten
dichloroacetic acid[no description available]medium10monocarboxylic acid;
organochlorine compound		astringent;
marine metabolite
1,3-dichloro-2-propanol[no description available]medium10organochlorine compound;
secondary alcohol		cross-linking reagent;
protic solvent
ethylene dibromide[no description available]medium10bromoalkane;
bromohydrocarbon		algal metabolite;
carcinogenic agent;
fumigant;
marine metabolite;
mouse metabolite;
mutagen
allyl chloride[no description available]medium20organochlorine compound
ethylene bromohydrin[no description available]medium10
3-Bromo-1-propanol[no description available]medium10primary alcohol
dibromoacetic acid[no description available]medium102-bromocarboxylic acid;
monocarboxylic acid		apoptosis inducer;
geroprotector;
marine metabolite
2-bromoacrolein[no description available]medium10
bromodichloroacetic acid[no description available]medium10
bromochloroacetic acid[no description available]medium102-bromocarboxylic acid;
monocarboxylic acid;
organochlorine compound
1,4-dichloro-2-butene[no description available]medium10organochlorine compound
mitobronitol[no description available]medium10alcohol;
organobromine compound
chlorine[no description available]medium20diatomic chlorine;
gas molecular entity		bleaching agent
2,3-dichlorophenol[no description available]medium10
2,3,4,6-tetrachlorophenol[no description available]medium10tetrachlorophenolxenobiotic metabolite
3,5-dichlorophenol[no description available]medium10dichlorophenol
5,6-dimethylbenzimidazole[no description available]medium10dimethylbenzimidazoleEscherichia coli metabolite;
human metabolite
hydroxocobalamin[no description available]medium10
paraquat[no description available]medium10organic cationgeroprotector;
herbicide
1,3-dichloro-1-propene[no description available]medium20
uracil[no description available]medium10pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
1,1,2,3-tetrachloropropene[no description available]medium20
proadifen[no description available]medium10diarylmethane
trichloroepoxypropane[no description available]medium10
cyanamide[no description available]medium10nitrile;
one-carbon compound		EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
Aneuploid0low10
Aneuploid Cell0low10
Aneuploidy0low10
Body Weight0low10
Fetal Death0low10
Fetal Demise0low10
Fetal Mummification0low10
Sensitivity and Specificity0low10