2-naphthoxyacetic acid profile

2-naphthoxyacetic acid, also known as NAA, is a synthetic auxin, a plant hormone that regulates growth and development. It is commonly used as a plant growth regulator in agriculture, horticulture, and forestry. NAA is typically applied as a spray, dust, or soil drench to stimulate root development, control fruit drop, and induce flowering. It is also used to promote fruit set and enhance fruit size. The synthesis of NAA involves the reaction of 2-naphthol with chloroacetic acid in the presence of a base. The effects of NAA on plants vary depending on the concentration, application method, and plant species. NAA is particularly effective in promoting root development in cuttings and seedlings. It can also be used to induce parthenocarpy, the development of fruit without fertilization. The importance of NAA lies in its ability to enhance plant productivity and yield. NAA is studied extensively to optimize its application and understand its mechanisms of action. Research focuses on developing more efficient and environmentally friendly formulations, exploring its role in plant stress responses, and investigating its potential for use in biotechnology.'

2-naphthoxyacetic acid: used as plant hormone to promote the growth of roots on clippings, to prevent fruit from falling prematurely; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	8422
CHEMBL ID	1732186
CHEBI ID	50397
SCHEMBL ID	25640
MeSH ID	M0052564

Synonym
(2-naphthyloxy)acetic acid [bsi:iso]
ai3-14654
2-naphthalenoxyacetic acid
nsc 2070
betapal
einecs 204-380-0
ccris 3156
acide naphtyloxyacetique [iso-french]
acide naphthyloxyacetique [french]
brn 1074148
BB 0217877
nsc-2070
(.beta.-naphthalenyloxy)acetic acid
acetic acid, (2-naphthalenyloxy)-
naphthoxyacetic acid
betoxon
.beta.-naphthoxyacetic acid
2-naphthoxyacetic acid
(2-naphthyloxy)acetic acid
.beta.-naphthyloxyacetic acid
acetic acid, (2-naphthyloxy)-
2-naphthyloxyacetic acid
(2-naphthloxy)acetic acid
(2-naphthoxy)acetic acid
gerlach 1396
nsc2070
2-noxa
o-(2-naphthyl)glycolic acid
bnoa
120-23-0
noxa
AC-907/25014305
CBDIVE_003164
OPREA1_727299
beta-naphthyloxyacetic acid
beta-naphthoxyacetic acid
CHEBI:50397 ,
(2-naphthalenyloxy)acetic acid
(beta-naphthalenyloxy)acetic acid
(naphthalen-2-yloxy)acetic acid
2-(2-naphthyloxy)acetic acid
2-naphthoxyacetic acid, 98%
2-naphthoxyacetic acid, bioreagent, plant cell culture tested, crystalline
NCGC00166229-01
STK117074
2-naphthalen-2-yloxyacetic acid
rzcjymobwvjqgv-uhfffaoysa-
inchi=1/c12h10o3/c13-12(14)8-15-11-6-5-9-3-1-2-4-10(9)7-11/h1-7h,8h2,(h,13,14)
AKOS000101579
MLS-0412048.0001
N0045
C18750
2-napthyloxyacetic acid
NCGC00255805-01
dtxcid0022195
dtxsid2042195 ,
cas-120-23-0
tox21_301390
acide naphtyloxyacetique
acide naphthyloxyacetique
717gvr334r ,
unii-717gvr334r
acetic acid, 2-(2-naphthalenyloxy)-
FT-0613129
(2-naphthyloxy)acetic acid [iso]
2-naphthoxyacetic acid [mi]
acetic acid, 2-naphthoxy-
betokson
noxa (naphthyloxyacetic acid)
(.beta.-naphthyloxy)acetic acid
2-naphthalenyloxyethanoic acid
2-(naphthalen-2-yloxy)acetic acid
SCHEMBL25640
KS-5264
bnoa, beta-naphthoxyacetic acid
(naphthalen-2-yloxy)-acetic acid
2-(2-naphthoxy)acetic acid
CHEMBL1732186
2-naphthalen-2-yloxyethanoic acid
cid_8422
2-(2-naphthalenyloxy)acetic acid
bdbm50
betokson super
(beta-naphthyloxy)acetic acid
W-108481
b-naphthoxyacetic acid
F0307-0743
mfcd00004066
2-naphthoxyacetic acid, pestanal(r), analytical standard
H11815
2-naphthoxyacetic acid, vetec(tm) reagent grade, 98%
2-naphthoxy acetic acid
glycollic acid 2-naphthyl ether
(2-naphthyloxy)acetic acid, 8ci, bsi, iso
2-(2-naphthalenyloxy)-acetic acid
(2-naphthalenyloxy)-acetic acid
(b-naphthalenyloxy)acetic acid
(2-naphthyloxy)-acetic acid
(b-naphthyloxy)acetic acid
CS-W015512
(2-naphthoxy)ethanoic acid
Q27122052
HY-W014796
2-naphthoxyaceticacid
EN300-18402
Z57246951
PD158315

Class	Description
naphthyloxyacetic acid
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Luciferase	Photinus pyralis (common eastern firefly)	Potency	39.9149	0.0072	15.7588	89.3584	AID1224835
SMAD family member 2	Homo sapiens (human)	Potency	21.8724	0.1737	34.3047	61.8120	AID1346859
SMAD family member 3	Homo sapiens (human)	Potency	21.8724	0.1737	34.3047	61.8120	AID1346859
nuclear receptor subfamily 1, group I, member 3	Homo sapiens (human)	Potency	61.1306	0.0010	22.6508	76.6163	AID1224838
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	9.7700	0.0002	29.3054	16,493.5996	AID743075
aryl hydrocarbon receptor	Homo sapiens (human)	Potency	61.1306	0.0007	23.0674	1,258.9301	AID743085
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	Homo sapiens (human)	Potency	43.2771	0.0017	23.8393	78.1014	AID743083
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
dual specificity protein phosphatase 3	Homo sapiens (human)	IC50 (µMol)	99.5000	0.4000	9.3610	90.0000	AID1957; AID1958
tyrosine-protein phosphatase non-receptor type 22 isoform 1	Homo sapiens (human)	IC50 (µMol)	100.0000	0.4800	2.6449	8.3270	AID449726; AID449727
dual specificity protein phosphatase 6	Rattus norvegicus (Norway rat)	IC50 (µMol)	99.0000	0.8320	24.1190	48.2000	AID1055
tyrosine-protein phosphatase non-receptor type 7 isoform 2	Homo sapiens (human)	IC50 (µMol)	88.6750	0.1000	12.7265	63.0000	AID1077; AID2068; AID449736
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Rattus norvegicus (Norway rat)	IC50 (µMol)	99.0000	0.0003	2.7232	10.0000	AID1957
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Rattus norvegicus (Norway rat)	IC50 (µMol)	99.0000	0.0003	2.7232	10.0000	AID1957
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Rattus norvegicus (Norway rat)	IC50 (µMol)	99.0000	0.0003	2.6638	10.0000	AID1957
Amine oxidase [flavin-containing] B	Rattus norvegicus (Norway rat)	IC50 (µMol)	100.0000	0.0004	0.7649	12.5000	AID1958
Amine oxidase [flavin-containing] A	Rattus norvegicus (Norway rat)	IC50 (µMol)	100.0000	0.0007	1.9798	12.5000	AID1958
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Rattus norvegicus (Norway rat)	IC50 (µMol)	99.0000	0.0003	2.7232	10.0000	AID1957
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Assay ID	Title	Year	Journal	Article
AID1130306	Inhibition of glycolic acid oxidase (unknown origin) assessed as enzyme-mediated reduction of NaDCIP by sodium glycolate after 1 to 3 mins by spectrophotometer analysis	1979	Journal of medicinal chemistry, Jun, Volume: 22, Issue:6	Quantitative structure-activity relationships involving the inhibition of glycolic acid oxidase by derivatives of glycolic and glyoxylic acids.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (16.00)	18.7374
1990's	2 (8.00)	18.2507
2000's	7 (28.00)	29.6817
2010's	10 (40.00)	24.3611
2020's	2 (8.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	28 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
acetone methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).	1.99	1	ketone body; methyl ketone; propanones; volatile organic compound	EC 3.5.1.4 (amidase) inhibitor; human metabolite; polar aprotic solvent
methane Methane: The simplest saturated hydrocarbon. It is a colorless, flammable gas, slightly soluble in water. It is one of the chief constituents of natural gas and is formed in the decomposition of organic matter. (Grant & Hackh's Chemical Dictionary, 5th ed). methane : A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC).	2.53	2	alkane; gas molecular entity; mononuclear parent hydride; one-carbon compound	bacterial metabolite; fossil fuel; greenhouse gas
coumarin 2H-chromen-2-one: coumarin derivative	2.07	1	coumarins	fluorescent dye; human metabolite; plant metabolite
indoleacetamide indoleacetamide: article does not mention position of acetamide group; amide of indole-3-acetic acid (IAA), the natural auxin found in plants. indole-3-acetamide : A member of the class of indoles that is acetamide substituted by a 1H-indol-3-yl group at position 2. It is an intermediate in the production of plant hormone indole acetic acid (IAA).	2.31	1	indoles; monocarboxylic acid amide; N-acylammonia	bacterial metabolite; fungal metabolite; plant metabolite
indole [no description available]	2.31	1	indole; polycyclic heteroarene	Escherichia coli metabolite
indole-3-acetaldehyde indoleacetaldehyde : An aldehyde that is acetaldehyde substituted by an indolyl group.. indol-3-ylacetaldehyde : An indoleacetaldehyde that is acetaldehyde in which one of the methyl hydrogens are replaced by a indol-3-yl group. It is an intermediate metabolite in the metabolism of tryptophan.	2.31	1	indoleacetaldehyde	bacterial metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
indoleacetic acid indoleacetic acid: RN given refers to unlabeled parent cpd; structure in Merck Index, 9th ed, #4841. auxin : Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").. indole-3-acetic acid : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1H-indol-3-yl group.	3.17	5	indole-3-acetic acids; monocarboxylic acid	auxin; human metabolite; mouse metabolite; plant hormone; plant metabolite
naphthalene [no description available]	2.05	1	naphthalenes; ortho-fused bicyclic arene	apoptosis inhibitor; carcinogenic agent; environmental contaminant; mouse metabolite; plant metabolite; volatile oil component
phenylpyruvic acid phenylpyruvic acid: RN given refers to parent cpd. phenylpyruvate : A 2-oxo monocarboxylic acid anion resulting from deprotonation of the carboxy group of either keto- or enol-phenylpyruvic acid.. keto-phenylpyruvic acid : A 2-oxo monocarboxylic acid that is 3-phenylpropanoic acid substituted by an oxo group at position 2. It is an intermediate metabolite in the phenylalanine pathway.	1.95	1	2-oxo monocarboxylic acid	chromogenic compound; EC 6.4.1.1 (pyruvate carboxylase) inhibitor; fundamental metabolite
sulfites Sulfites: Inorganic salts of sulfurous acid.. sulfites : Any sulfurous acid derivative that is a salt or an ester of sulfurous acid.. organosulfonate oxoanion : An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid.. sulfite : A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3).	2	1	divalent inorganic anion; sulfur oxide; sulfur oxoanion
mandelic acid SAMMA: mandelic acid condensation polymer	1.95	1	2-hydroxy monocarboxylic acid; benzenes	antibacterial agent; human xenobiotic metabolite
caffeine [no description available]	1.96	1	purine alkaloid; trimethylxanthine	adenosine A2A receptor antagonist; adenosine receptor antagonist; adjuvant; central nervous system stimulant; diuretic; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; environmental contaminant; food additive; fungal metabolite; geroprotector; human blood serum metabolite; mouse metabolite; mutagen; plant metabolite; psychotropic drug; ryanodine receptor agonist; xenobiotic
3-phenyllactic acid 3-phenyllactic acid: alpha-hydroxy analog of phenylalanine; RN given refers to cpd without isomeric designation. 3-phenyllactic acid : A 2-hydroxy monocarboxylic acid that is lactic acid in which one of the methyl hydrogens is substituted by a phenyl group.	1.95	1	2-hydroxy monocarboxylic acid	human metabolite
4-phenylbutyric acid 4-phenylbutyric acid: RN refers to the parent cpd. 4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.	2.25	1	monocarboxylic acid	antineoplastic agent; apoptosis inducer; EC 3.5.1.98 (histone deacetylase) inhibitor; prodrug
piracetam Piracetam: A compound suggested to be both a nootropic and a neuroprotective agent.	2.08	1	organonitrogen compound; organooxygen compound
adenosine monophosphate Adenosine Monophosphate: Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.	1.98	1	adenosine 5'-phosphate; purine ribonucleoside 5'-monophosphate	adenosine A1 receptor agonist; cofactor; EC 3.1.3.1 (alkaline phosphatase) inhibitor; EC 3.1.3.11 (fructose-bisphosphatase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
phenylalanine Phenylalanine: An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.. L-phenylalanine : The L-enantiomer of phenylalanine.. phenylalanine : An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.	1.98	1	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; phenylalanine; proteinogenic amino acid	algal metabolite; EC 3.1.3.1 (alkaline phosphatase) inhibitor; Escherichia coli metabolite; human xenobiotic metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
cycloheximide Cycloheximide: Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.. cycloheximide : A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus.	2.25	1	antibiotic fungicide; cyclic ketone; dicarboximide; piperidine antibiotic; piperidones; secondary alcohol	anticoronaviral agent; bacterial metabolite; ferroptosis inhibitor; neuroprotective agent; protein synthesis inhibitor
tryptophan Tryptophan: An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.. tryptophan : An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3.	2.31	1	erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid; tryptophan zwitterion; tryptophan	antidepressant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
methylene chloride Methylene Chloride: A chlorinated hydrocarbon that has been used as an inhalation anesthetic and acts as a narcotic in high concentrations. Its primary use is as a solvent in manufacturing and food technology.. dichloromethane : A member of the class of chloromethanes that is methane in which two of the hydrogens have been replaced by chlorine. A dense, non-flammible colourless liquid at room temperature (b.p. 40degreeC, d = 1.33) which is immiscible with water, it is widely used as a solvent, a paint stripper, and for the removal of caffeine from coffee and tea.	1.99	1	chloromethanes; volatile organic compound	carcinogenic agent; polar aprotic solvent; refrigerant
naphthaleneacetamide naphthaleneacetamide: RN given refers to compound with unknown acetamide position. 1-naphthaleneacetamide : A member of the class of naphthalenes that is naphthalene which is substituted by a 2-amino-2-oxoethyl group at position 1. It is a synthetic auxin that is widely used in agriculture to promote the growth of numerous fruits, for root cuttings and as a fruit thinning agent.	2.08	1	naphthalenes; primary carboxamide	synthetic auxin
1-naphthaleneacetic acid 1-naphthaleneacetic acid: a plant growth regulator; RN given refers to parent cpd. naphthylacetic acid : A monocarboxylic acid that is naphthalene substituted by a carboxymethyl group at any position.. 1-naphthaleneacetic acid : A naphthylacetic acid substituted by a carboxymethyl group at position 1.	3.03	4	naphthylacetic acid	synthetic auxin
alpha-naphthylphthalamic acid alpha-naphthylphthalamic acid: RN given refers to parent cpd; structure. naptalam : A dicarboxylic acid monoamide which results from addition of one equivalent of 1-naphthylamine to phthalic anhydride.	2.52	2	carboxylic acid; dicarboxylic acid monoamide; N-(1-naphthyl)carboxamide	herbicide
thiazoles [no description available]	2.02	1	1,3-thiazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
2-naphthylacetic acid 2-naphthylacetic acid: RN given refers to parent cpd. 2-naphthylacetic acid : A naphthylacetic acid carrying a carboxy group at position 2.	2.08	1	naphthylacetic acid
alpha-hydroxy-gamma-methylmercaptobutyric acid alpha-hydroxy-gamma-methylmercaptobutyric acid: RN given refers to parent cpd	1.95	1	thia fatty acid
phenylglyoxylic acid phenylglyoxylic acid: styrene metabolite. phenylglyoxylic acid : A 2-oxo monocarboxylic acid that is glyoxylic acid in which the aldehyde hydrogen is substituted by a phenyl group.	1.95	1	2-oxo monocarboxylic acid	biomarker; human xenobiotic metabolite
2-aminothiazoline 2-aminothiazoline: RN given refers to parent cpd; structure in first source & in Negwer, 5th ed, #97. 4,5-dihydro-1,3-thiazol-2-amine : A 1,3-thiazole that is 4,5-dihydro-1,3-thiazole substituted by an amino group at position 2.	2.02	1	1,3-thiazoles; primary amino compound
(4-tert-Butyl-phenoxy)-acetic acid [no description available]	1.95	1	monocarboxylic acid
4-hydroxyphenoxyacetic acid [no description available]	1.95	1	monocarboxylic acid
guaiacoxyacetic acid guaiacoxyacetic acid: structure given in first source	1.95	1
phenoxyacetic acid phenoxyacetic acid : A monocarboxylic acid that is the O-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes.	1.95	1	aromatic ether; monocarboxylic acid	allergen; Aspergillus metabolite; human xenobiotic metabolite; plant growth retardant
sodium sulfite [no description available]	2	1	inorganic sodium salt; sulfite salt	food preservative; reducing agent
4-chlorophenoxyacetic acid 4-chlorophenoxyacetic acid: RN given refers to parent cpd; structure. (4-chlorophenoxy)acetic acid : A chlorophenoxyacetic acid that is phenoxyacetic acid carrying a chloro substituent at position 4.	1.95	1	chlorophenoxyacetic acid; monochlorobenzenes	phenoxy herbicide
iodine [no description available]	2	1	halide anion; monoatomic iodine	human metabolite
triazoles Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.	2.31	1	1,2,3-triazole
1-naphthoxyacetic acid [no description available]	2.05	1	naphthyloxyacetic acid
alpha-hydroxyisocaproic acid alpha-hydroxyisocaproic acid: alpha-hydroxy analog of leucine; RN given refers to cpd without isomeric designation. 2-hydroxy-4-methylvaleric acid : A valeric acid derivative having a hydroxy substituent at the 2-position and a methyl substituent at the 4-position; an alpha-hydroxy analogue of leucine. A bacterial metabolite, it has also been isolated from amniotic fluid, was found in a patient with dihydrolipoyl dehydrogenase deficiency and is present in the urine of patients with short bowel syndrome.	1.95	1	2-hydroxy fatty acid; branched-chain fatty acid	metabolite
salicylamide-2-acetic acid salicylamide-2-acetic acid: solubilizer of theophylline in Solosin; RN given refers to parent cpd	1.95	1	monocarboxylic acid
2-chloromandelic acid 2-chloromandelic acid: structure in first source	1.95	1
4-fluoro-alpha-hydroxybenzeneacetic acid 4-fluoro-alpha-hydroxybenzeneacetic acid: an aprepitant urinary metabolite; structure in first source	1.95	1
3-chloro-4-hydroxyphenylacetic acid 3-chloro-4-hydroxyphenylacetic acid: RN given refers to parent cpd. (3-chloro-4-hydroxyphenyl)acetic acid : A hydroxy monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a 3-chloro-4-hydroxyphenyl group. It is a major chlorinated metabolite of chlorotyrosine.	2.05	1	hydroxy monocarboxylic acid; monochlorobenzenes; phenols	mammalian metabolite
alpha-ketocaproic acid alpha-ketocaproic acid: RN given refers to parent cpd. 2-oxohexanoic acid : A straight-chain fatty acid consisting of hexanoic acid having an oxo group at position 2.	1.95	1	2-oxo monocarboxylic acid; medium-chain fatty acid; oxo fatty acid; straight-chain fatty acid	human blood serum metabolite
indole-3-acetonitrile indole-3-acetonitrile: occurs in edible cruciferous vegetables. indole-3-acetonitrile : A nitrile that is acetonitrile where one of the methyl hydrogens is substituted by a 1H-indol-3-yl group.	2.31	1	indoles; nitrile	auxin; human xenobiotic metabolite; plant hormone; plant metabolite
betadex beta-Cyclodextrins: Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.	2.75	3	cyclodextrin
5-(4-chlorophenyl)-4h-1,2,4-triazole-3-thiol 5-(4-chlorophenyl)-4H-1,2,4-triazole-3-thiol: a YUCCA enzyme inhibitor; structure in first source	2.31	1	triazoles
2-mercaptobenzimidazole 2-mercaptobenzimidazole: purine synthesis antimetabolite; RN given refers to parent cpd	2.31	1
warfarin Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.	2.07	1	benzenes; hydroxycoumarin; methyl ketone

Condition	Relationship Strength	Studies
Eye Diseases, Hereditary Transmission of gene defects or chromosomal aberrations/abnormalities which are expressed in extreme variation in the structure or function of the eye. These may be evident at birth, but may be manifested later with progression of the disorder.	2.25	1
Retinal Diseases Diseases involving the RETINA.	2.25	1
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.08	1
Amnesia-Memory Loss [description not available]	2.08	1
Amnesia Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)	2.08	1

2-naphthoxyacetic acid

Description

Cross-References

Synonyms (107)

Drug Classes (1)

Protein Targets (18)

Potency Measurements

Inhibition Measurements

Bioassays (1)

Research

Studies (25)

Market Indicators

Research Demand Index: 30.68

Study Types