flucytosine has been researched along with Sensitivity and Specificity in 14 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Invasive candidiasis is associated with high morbidity and mortality." | 1.35 | Direct antifungal susceptibility testing of positive Candida blood cultures by sensititre YeastOne. ( Avolio, M; Bruschetta, G; Camporese, A; De Rosa, R; Grosso, S, 2009) |
| " Flucytosine combined with amphotericin B produced little or no reduction of the MIC compared with amphotericin B alone." | 1.31 | Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp. ( Chaiprasert, A; Prariyachatigul, C; Rungsipanuratn, W; Srimuang, S; Tanphaichitra, D, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sortino, M | 1 |
| Delgado, P | 1 |
| Juárez, S | 1 |
| Quiroga, J | 1 |
| Abonía, R | 1 |
| Insuasty, B | 1 |
| Nogueras, M | 1 |
| Rodero, L | 1 |
| Garibotto, FM | 1 |
| Enriz, RD | 1 |
| Zacchino, SA | 1 |
| Szweda, P | 1 |
| Gucwa, K | 1 |
| Naumiuk, L | 1 |
| Romanowska, E | 1 |
| Dzierzanowska-Fangrat, K | 1 |
| Brillowska-Dabrowska, A | 1 |
| Wojciechowska-Koszko, I | 1 |
| Milewski, S | 1 |
| Avolio, M | 1 |
| Grosso, S | 1 |
| Bruschetta, G | 1 |
| De Rosa, R | 1 |
| Camporese, A | 1 |
| Serve, KM | 1 |
| Yáñez, JA | 1 |
| Remsberg, CM | 1 |
| Davies, NM | 1 |
| Black, ME | 1 |
| Krishnan, S | 1 |
| Ostrosky-Zeichner, L | 1 |
| Bicmen, C | 1 |
| Doluca, M | 1 |
| Gulat, S | 1 |
| Gunduz, AT | 1 |
| Tuksavul, F | 1 |
| Bourbeau, D | 1 |
| Lavoie, G | 1 |
| Nalbantoglu, J | 1 |
| Massie, B | 1 |
| Stronati, M | 1 |
| Decembrino, L | 1 |
| Matsumoto, FE | 1 |
| Dias, AL | 1 |
| Melhem, MS | 1 |
| Szeszs, MW | 1 |
| Auler, ME | 1 |
| Ruiz, LS | 1 |
| Gonçalves da Silva, E | 1 |
| Gandra, RF | 1 |
| Paula, CR | 1 |
| Gamelin, E | 1 |
| Boisdron-Celle, M | 1 |
| Turcant, A | 1 |
| Larra, F | 1 |
| Allain, P | 1 |
| Robert, J | 1 |
| Marco, F | 1 |
| Pfaller, MA | 1 |
| Messer, SA | 1 |
| Jones, RN | 1 |
| Srimuang, S | 1 |
| Prariyachatigul, C | 1 |
| Chaiprasert, A | 1 |
| Rungsipanuratn, W | 1 |
| Tanphaichitra, D | 1 |
| Toraño, JS | 1 |
| Vermes, A | 1 |
| Guchelaar, HJ | 1 |
| Olsen, BA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PROCAS: Study Observational Prospective and Multicenter to Determine the Clinic Effectiveness and the Safety of Caspofungin Acetate (CANCIDAS®) in the Treatment of Invader Fungal Infection[NCT00388167] | 320 participants (Anticipated) | Observational | 2004-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for flucytosine and Sensitivity and Specificity
| Article | Year |
|---|---|
Neonatal invasive candidiasis.
Topics: Age Factors; Amphotericin B; Antifungal Agents; Candidiasis; Drug Therapy, Combination; Fluconazole; | 2006 |
13 other studies available for flucytosine and Sensitivity and Specificity
| Article | Year |
|---|---|
Synthesis and antifungal activity of (Z)-5-arylidenerhodanines.
Topics: Antifungal Agents; Computer Simulation; Drug Design; Microbial Sensitivity Tests; Microwaves; Mitosp | 2007 |
Evaluation of possibilities in identification and susceptibility testing for Candida glabrata clinical isolates with the Integral System Yeast Plus (ISYP).
Topics: Amphotericin B; Antifungal Agents; Candida glabrata; Candidiasis; Fluconazole; Flucytosine; Humans; | 2014 |
Direct antifungal susceptibility testing of positive Candida blood cultures by sensititre YeastOne.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Drug Resistance, Fungal; Fluconazole; Flucy | 2009 |
Development and validation of a rapid and sensitive HPLC method for the quantification of 5-fluorocytosine and its metabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Chromatography, High Pressure Liquid; Fl | 2010 |
Invasive candidiasis in the intensive care unit.
Topics: Algorithms; Antifungal Agents; Azoles; Biomarkers; Candidiasis; Chemoprevention; Critical Care; Cros | 2010 |
Species level identification and antifungal susceptibility of yeasts isolated from various clinical specimens and evaluation of Integral System Yeasts Plus.
Topics: Amphotericin B; Candida; Colorimetry; Drug Resistance, Multiple, Fungal; Fluconazole; Flucytosine; H | 2012 |
Suicide gene therapy with an adenovirus expressing the fusion gene CD::UPRT in human glioblastomas: different sensitivities correlate with p53 status.
Topics: Adenoviridae; Antimetabolites; Brain Neoplasms; Cytosine Deaminase; Flucytosine; Gene Expression Pro | 2004 |
Antifungal susceptibility of bloodstream yeasts isolated at a public children's hospital in Brazil: comparison of the Etest and the AFST-EUCAST microdilution method.
Topics: Amphotericin B; Antifungal Agents; Blood; Brazil; Candida; Child; Child, Preschool; Fluconazole; Flu | 2007 |
Rapid and sensitive high-performance liquid chromatographic analysis of halogenopyrimidines in plasma.
Topics: 5-Methylcytosine; Antimetabolites, Antineoplastic; Bromouracil; Chromatography, High Pressure Liquid | 1997 |
Activity of MK-0991 (L-743,872), a new echinocandin, compared with those of LY303366 and four other antifungal agents tested against blood stream isolates of Candida spp.
Topics: Amphotericin B; Anidulafungin; Anti-Bacterial Agents; Antifungal Agents; Blood; Candida; Caspofungin | 1998 |
Antifungal drug combinations for Cryptococcus neoformans and Prototheca spp.
Topics: Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Drug Therapy, Combination; Flucytosine; | 2000 |
Simultaneous determination of flucytosine and fluorouracil in human plasma by high-performance liquid chromatography.
Topics: Calibration; Chromatography, High Pressure Liquid; Flucytosine; Fluorouracil; Humans; Reference Stan | 2001 |
Hydrophilic interaction chromatography using amino and silica columns for the determination of polar pharmaceuticals and impurities.
Topics: Acetamides; Acyclovir; Amines; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; F | 2001 |