Proteins > Estrogen receptor
Page last updated: 2024-08-07 16:07:54

Estrogen receptor

An estrogen receptor that is encoded in the genome of mouse. [OMA:P19785, PRO:DNx]

Synonyms

ER;
ER-alpha;
Estradiol receptor;
Nuclear receptor subfamily 3 group A member 1

Research

Bioassay Publications (8)

TimeframeStudies on this Protein(%)All Drugs %
pre-19901 (12.50)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Compounds (77)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
ketoconazoleMus musculus (house mouse)Ki0.065011
lavendustin aMus musculus (house mouse)IC508.000014
2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acidMus musculus (house mouse)IC5010.000014
yohimbineMus musculus (house mouse)Ki0.084012
amiloride hydrochloride, anhydrousMus musculus (house mouse)IC506.884810
4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenolMus musculus (house mouse)IC500.033211
erb 041Mus musculus (house mouse)IC500.746011
cid755673Mus musculus (house mouse)IC500.741610
way 200070Mus musculus (house mouse)IC500.132011

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
indoprofenMus musculus (house mouse)EC501.518010
frentizoleMus musculus (house mouse)EC500.899010
efuamideMus musculus (house mouse)EC509,069.820010
1,4-di(2'-thienyl)-1,4-butadioneMus musculus (house mouse)EC50227.894010
N-(4-methoxyphenyl)-1,3-benzothiazol-2-amineMus musculus (house mouse)EC5020.378010
DubamineMus musculus (house mouse)EC5016.743010
resveratrolMus musculus (house mouse)EC505.203010
N-[4-(diethylamino)phenyl]-2-furancarboxamideMus musculus (house mouse)EC502.499010
6-methoxy-2-(4-methoxyphenyl)-1-benzopyran-4-oneMus musculus (house mouse)EC503.918010
vu0038882Mus musculus (house mouse)EC505.562010
N-(4-methoxyphenyl)-2-benzofurancarboxamideMus musculus (house mouse)EC50142.792010
1-(1,3-benzothiazol-2-yl)-3-phenylureaMus musculus (house mouse)EC5027.210010
N-[[(6-methyl-1,3-benzothiazol-2-yl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamideMus musculus (house mouse)EC502.227010
nsc185058Mus musculus (house mouse)EC502.028010
2-[(2-fluorophenyl)methylthio]-5-(4-methylphenyl)-1,3,4-oxadiazoleMus musculus (house mouse)EC504.629010
N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-furancarboxamideMus musculus (house mouse)EC501.677010
N-[4-(2-methyl-4-thiazolyl)phenyl]benzamideMus musculus (house mouse)EC500.761010
5-bromo-N-(4-propan-2-ylphenyl)-2-furancarboxamideMus musculus (house mouse)EC501.707010
6-(1,3-benzoxazol-2-yl)-1,3-benzothiazol-2-amineMus musculus (house mouse)EC501.387010
6-(4-chlorophenyl)-2-methyl-3-pyridinecarboxylic acid methyl esterMus musculus (house mouse)EC504.442010
2-methyl-N-(2-naphthalenyl)-3-furancarboxamideMus musculus (house mouse)EC503.700010
3-[[(3-chloro-4-ethoxyphenyl)-oxomethyl]amino]benzoic acidMus musculus (house mouse)EC5047.807010
2-methoxy-N-(4-methylphenyl)-4-(methylthio)benzamideMus musculus (house mouse)EC503.047010
1-cyclohexyl-3-(2,3-dihydro-1,4-benzodioxin-6-yl)ureaMus musculus (house mouse)EC5018.205010
5-methyl-1-phenyl-4-pyrazolecarboxylic acid (4-methoxyphenyl) esterMus musculus (house mouse)EC5049.524010
N-(2-phenyl-6-imidazo[1,2-a]pyridinyl)acetamideMus musculus (house mouse)EC502.699010
benzoic acid (2-oxo-2-thiophen-2-ylethyl) esterMus musculus (house mouse)EC5012.559010
3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazoleMus musculus (house mouse)EC509,038.190010
N2-(4-methylphenyl)-6-[(2-pyrimidinylthio)methyl]-1,3,5-triazine-2,4-diamineMus musculus (house mouse)EC508,804.660010
4-[methyl-(4-thiophen-2-yl-2-thiazolyl)amino]phenolMus musculus (house mouse)EC503.855010
N-(3-chloro-4-methylphenyl)-2-(2-formylphenoxy)acetamideMus musculus (house mouse)EC503.883010
3-[2-(4-aminoanilino)-4-thiazolyl]-1-benzopyran-2-oneMus musculus (house mouse)EC502.019010
N-[4-[2-[(6-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamideMus musculus (house mouse)EC501.000010
1-(4-bromophenyl)-4-[1-naphthalenyl(oxo)methyl]-3-pyrazolecarboxylic acid ethyl esterMus musculus (house mouse)EC503.002010
N-(4-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamideMus musculus (house mouse)EC5010.395010
4-(5-amino-4-phenyl-1-pyrazolyl)benzoic acidMus musculus (house mouse)EC5046.238010
N-[5-(4-tert-butylphenyl)-1,3,4-thiadiazol-2-yl]-2-methoxyacetamideMus musculus (house mouse)EC5011.027010
N-(2,3-dihydro-1H-inden-5-yl)-5-methyl-2-pyrazinecarboxamideMus musculus (house mouse)EC502.454010
4-(4-chlorophenyl)-1-(6-fluoro-2-pyridinyl)-3-pyrazolamineMus musculus (house mouse)EC500.675010
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-propan-2-ylphenyl) esterMus musculus (house mouse)EC501.553010
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-methylphenyl) esterMus musculus (house mouse)EC501.928010
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-tert-butylphenyl) esterMus musculus (house mouse)EC503.632010
3-hydroxybenzoic acid [2-(1H-indol-3-yl)-2-oxoethyl] esterMus musculus (house mouse)EC5014.620010
2-nitrobenzoic acid [1-(4-methylphenyl)-1-oxopropan-2-yl] esterMus musculus (house mouse)EC509.076010
N-(2-methoxy-3-dibenzofuranyl)-2-oxolanecarboxamideMus musculus (house mouse)EC505.782010
6-[(phenylmethylthio)methyl]imidazo[2,1-b]thiazoleMus musculus (house mouse)EC5012.577010
4-amino-2-(butylthio)-5-pyrimidinecarboxylic acid ethyl esterMus musculus (house mouse)EC5046.227010
4-[(1-methyl-2-oxo-4-quinolinyl)oxy]-N-(4-methyl-2-pyridinyl)butanamideMus musculus (house mouse)EC5010.469010
7-[(4-methyl-1-piperazinyl)methyl]-5-(phenylmethoxymethyl)-8-quinolinolMus musculus (house mouse)EC5011.024010
N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloroethyl) esterMus musculus (house mouse)EC500.059010
2-(4-phenyl-1-piperazinyl)quinoxalineMus musculus (house mouse)EC501.613010
3-(5-bromo-2-furanyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazoleMus musculus (house mouse)EC502.011010
3-[(4-methoxyphenoxy)methyl]-N-(4-nitro-1-pyrazolyl)benzamideMus musculus (house mouse)EC506,456.810010
biochanin aMus musculus (house mouse)EC5055.941010
5,7-dihydroxy-4',6-dimethoxyflavoneMus musculus (house mouse)EC502.290010
7,4'-dimethoxy-5-hydroxyisoflavoneMus musculus (house mouse)EC501.725010
5-methoxy-3,6-diphenyl-1,2,4-triazineMus musculus (house mouse)EC5038.932010
N-methyl-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amineMus musculus (house mouse)EC50102.034010
1-(1,3-benzodioxol-5-yl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)ureaMus musculus (house mouse)EC500.114010
2-chloro-3-[2-(4-methylphenyl)-5-tetrazolyl]pyridineMus musculus (house mouse)EC504.752010
kf38789Mus musculus (house mouse)EC502.328010

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
salicylic acidMus musculus (house mouse)Kis19,400.000014
gyki 52466Mus musculus (house mouse)ED5025.300016
4-nitrophenyl sulfateMus musculus (house mouse)Kis10,000.000014
estrone sulfateMus musculus (house mouse)Kis2,100.000014
cfm 2Mus musculus (house mouse)ED5012.600016
4,5-dihydro-7,8-dimethoxy-1-phenyl-3h-2,3-benzodiazepin-4-oneMus musculus (house mouse)ED5031.800016
hypocrellin aMus musculus (house mouse)PKC44.000012