Compounds > pacific blue succinimidyl ester
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pacific blue succinimidyl ester

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Pacific Blue succinimidyl ester: a fluorescent dye [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

pacific blue succinimidyl ester : An N-hydroxysuccinimide ester derived from 6,8-difluoro-7-hydroxycoumarin-3-carboxylic acid (pacific blue). A fluorescent dye of excitation wavelength 403 nm and emission wavelength 455 nm. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID56927770
CHEBI ID63240
SCHEMBL ID13494176
MeSH IDM0498471

Synonyms (26)

Synonym
pacific blue n-hydroxysuccinimidyl ester
6,8-difluoro-7-hydroxy-2-oxo-2h-chromene-3-carboxylic acid succinimidyl ester
pacific blue succinimidyl ester
6,8-difluoro-7-hydroxy-2-oxo-2h-chromene-3-carboxylic acid n-hydroxysuccinimidyl ester
CHEBI:63240
1-{[(6,8-difluoro-7-hydroxy-2-oxo-2h-chromen-3-yl)carbonyl]oxy}pyrrolidine-2,5-dione
SCHEMBL13494176
3-carboxy-6,8-difluoro-7-hydroxycoumarin succinimidyl ester
mfcd28155193
6,8-difluoro-7-hydroxy-2-oxo-2h-1-benzopyran-3-carboxylic acid 2,5-dioxo-1-pyrrolidinyl ester
215868-33-0
(2,5-dioxopyrrolidin-1-yl) 6,8-difluoro-7-hydroxy-2-oxochromene-3-carboxylate
J-014158
Q27132506
ocean blue, se
3-carboxy-6,8-difluoro-7-hydroxycoumaryl succinimidyl ester
AT21712
2,5-dioxopyrrolidin-1-yl 6,8-difluoro-7-hydroxy-2-oxo-2h-chromene-3-carboxylate
pacific blue nhs ester
BP-27948
pb succinimidyl ester
HY-133532
CS-0120928
DTXSID701304383
pb nhs ester
AKOS040757365
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
fluorochromeA fluorescent dye used to stain biological specimens.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
hydroxycoumarinAny coumarin carrying at least one hydroxy substituent.
organofluorine compoundAn organofluorine compound is a compound containing at least one carbon-fluorine bond.
N-hydroxysuccinimide esterAn ester of N-hydroxysuccinimide.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 17.69

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index17.69 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (17.69)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
benzoxazoles
1,3-benzoxazole : A benzoxazole in which the benzene ring is fused to a 1,3-oxazole ring across positions 4 and 5.. benzoxazole : Compounds based on a fused 1,2- or 1,3-oxazole and benzene bicyclic ring skeleton.		2.06101,3-benzoxazoles;
mancude organic heterobicyclic parent
silver
Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.		2.4620copper group element atom;
elemental silver		Escherichia coli metabolite
gold
Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.		2.110copper group element atom;
elemental gold
lithium
Lithium: An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.		2.0310alkali metal atom
carbocyanines
Carbocyanines: Compounds that contain three methine groups. They are frequently used as cationic dyes used for differential staining of biological materials.		2.0610cyanine dye;
organic iodide salt		fluorochrome
yo-pro 1
oxazole yellow: structure in first source. Yo-Pro-1 : An unsymmetrical C1 cyanine dye having 1,3-benzoxazol-2-yl and quinolinium-4-yl substituents.		2.0610cyanine dye;
organic iodide salt;
quaternary ammonium salt		fluorochrome
cyanine dye 3
cyanine dye 3: structures of Cy3 derivatives given in first source		2.0610
ConditionIndicatedRelationship StrengthStudiesTrials
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.0510