Disperse Red 1 : An azo dye with a structure consisting of nitrobenzene substituted on the 4-position of the phenyl group with a 4-[N-ethyl-N-(2-hydroxyethyl)]phenylazo group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 17886 |
| CHEBI ID | 63557 |
| SCHEMBL ID | 148266 |
| SCHEMBL ID | 532332 |
| MeSH ID | M0189219 |
| Synonym |
|---|
| celliton sacrlet b |
| wo 4 |
| 4-nitro-4'-(ethyl(2-hydroxyethyl)amino)azobenzene |
| interchem disperse scarlet bh |
| 2-(ethyl(4-((4-nitrophenyl)azo)phenyl)amino)ethanol |
| c.i. solvent red 14 |
| einecs 220-704-3 |
| diacelliton fast scarlet b |
| dispersol scarlet b |
| nsc 57019 |
| ethanol, 2-(ethyl(4-((4-nitrophenyl)azo)phenyl)amino)- |
| cibacet scarlet 2b |
| calcosyn brilliant scarlet bn |
| safaritone scarlet b |
| supracet fast scarlet b |
| durgacet scarlet b |
| c.i. disperse red 1 |
| cibacete scarlet brn |
| setacyl scarlet b |
| monocel scarlet b |
| nacelan scarlet csb |
| eniacyl scarlet b |
| acetate fast scarlet b |
| amacel scarlet gb |
| celliton scarlet b |
| nsc57019 |
| neosetile scarlet b |
| diacelliton scarlet b |
| eastone scarlet bg |
| microsetile scarlet b |
| celliton discharge scarlet b |
| celutate scarlet bh |
| ethanol, 2-[ethyl[4-[(4-nitrophenyl)azo]phenyl]amino]- |
| fenacet scarlet b |
| c.i. 11110 |
| dispersive ruby zh |
| dispersol fast scarlet b |
| silotras scarlet tsr |
| reliton scarlet ba |
| acetamine scarlet b |
| tertranese scarlet n-b |
| nsc-57019 |
| scarlet reliton ba |
| acetoquinone light scarlet blz |
| setacyl scarlet rna |
| cilla scarlet b |
| disperse scarlet zh |
| serisol fast scarlet bd |
| 4-nitro-4'-[ethyl(2-hydroxyethyl)amino]azobenzene |
| nyloquinone red n |
| 2872-52-8 |
| kayalon fast scarlet b |
| interchem hisperse scarlet bh |
| cibacet scarlet bs |
| disperse red zh |
| interchem acetate scarlet b |
| setacyl scarlet 2bd |
| serinyl hoisery scarlet bd |
| disperse scarlet b |
| celliton red b |
| miketon fast scarlet b |
| reltion scarlet b |
| cibacet scarlet brn |
| celliton scarlet ba-cf |
| disperse red 1 |
| disperse red 1, dye content 95 % |
| NCIOPEN2_007504 |
| 2-[n-ethyl-4-[(4-nitrophenyl)diazenyl]anilino]ethanol |
| 4-[ethyl(2-hydroxyethyl)amino]-4'-nitroazobenzene |
| ccris 9420 |
| ethanol, 2-(ethyl(4-(2-(4-nitrophenyl)diazenyl)phenyl)amino)- |
| FT-0625334 |
| 2-[n-ethyl-4-(4-nitrophenylazo)phenyl-amino]ethanol |
| CHEBI:63557 , |
| 4-[n-(2-hydroxyethyl)-n-ethylamino]-4'-nitroazobenzene |
| 4-[n-ethyl-n-(beta-hydroxyethyl)]amino-4'-nitroazobenzene |
| 2-(ethyl{4-[(e)-(4-nitrophenyl)diazenyl]phenyl}amino)ethanol |
| trans-4-[n-ethyl-n-(2-hydroxyethyl)amino]-4'-nitroazobenzene |
| EPITOPE ID:161744 |
| AKOS015902998 |
| SCHEMBL148266 |
| SCHEMBL532332 |
| DTXSID6062678 |
| m5utp |
| W-109833 |
| 2-[ethyl[4-[(4-nitrophenyl)azo]phenyl]amino]ethanol |
| GS-6070 |
| 2-[ethyl({4-[(e)-2-(4-nitrophenyl)diazen-1-yl]phenyl})amino]ethan-1-ol |
| disperse red 1, dye content 50 % |
| disperse red 1, analytical standard |
| c.i.disperse red 1 |
| (e)-2-(ethyl(4-((4-nitrophenyl)diazenyl)phenyl)amino)ethanol |
| 163931-45-1 |
| 2-(ethyl(4-((4-nitrophenyl)diazenyl)phenyl)amino)ethanol |
| 4-nitro-4'-[n-ethyl-n-(2-hydroxyethyl)-amino]azobenzene |
| Q27132688 |
| 2-[n-ethyl-4-(4-nitrophenyl)azoanilino]ethanol |
| Q26841347 |
| HY-D0342 |
| CS-0010347 |
| 2-ethyl4-(4-nitrophenyl)azophenylaminoethanol |
| H10496 |
| (e)-2-(ethyl(4-((4-nitrophenyl)diazenyl)phenyl)amino)ethan-1-ol |
| disperse red 1 100 microg/ml in acetonitrile |
| AKOS040751608 |
| PD158024 |
Disperse Red 1 (DR1) is an azo dye that can reach the aquatic environment through the discharge of textile industrial wastewaters.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Disperse Red 1 (DR1) is an azo dye that can reach the aquatic environment through the discharge of textile industrial wastewaters. " | ( CYP-dependent induction of glutathione S-transferase in Daphnia similis exposed to a disperse azo dye. Dafre, AL; de Aragão Umbuzeiro, G; Franciscon, E; Yu, TH, 2015) | 1.86 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " Their toxic properties are related to the nature and position of the substituents with respect to the aromatic rings and amino nitrogen atom." | ( Differential toxicity of Disperse Red 1 and Disperse Red 13 in the Ames test, HepG2 cytotoxicity assay, and Daphnia acute toxicity test. Caloto-Oliveira, A; Chequer, FM; de-Almeida, G; Dorta, DJ; Ferraz, ER; Oliveira, DP; Umbuzeiro, GA; Zanoni, MV, 2011) | 0.67 |
| " Studies showed that some classes of dyes, mainly azo dyes and their by-products, exert adverse effects on humans and local biota, since the wastewater treatment systems and water treatment plants were found to be ineffective in removing the color and reducing toxicity of some dyes." | ( Hepatotoxicity assessment of the azo dyes disperse orange 1 (DO1), disperse red 1 (DR1) and disperse red 13 (DR13) in HEPG2 cells. Boubriak, O; de Oliveira, DP; Ferraz, ER; Li, Z, 2012) | 0.62 |
| " To assess the toxic effects of DR1 on reproduction, sexually mature male mice (Mus musculus, strain CF-1) were orally (gavage) treated with single doses of the compound at 20, 100 and 500 mg/kg body weight." | ( Disperse Red 1 (textile dye) induces cytotoxic and genotoxic effects in mouse germ cells. Bustos-Obregon, E; Fernandes, FH; Salvadori, DM, 2015) | 1.86 |
| " The intermediates were further degraded and toxicity was then reduced to non toxic levels after 45 min experiment, when 98% of the initial concentration of DR1 was degraded and mineralization achieved 55%." | ( Monitoring ecotoxicity of disperse red 1 dye during photo-Fenton degradation. da Silva Leite, L; de Aragão Umbuzeiro, G; de Souza Maselli, B; Pupo Nogueira, RF, 2016) | 0.73 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, the use of an additional hydrogen source or photosensitizer has dosage limitations in such applications." | ( Photodegradation mechanism and rate improvement of chlorinated aromatic dye in non-ionic surfactant solutions. Chu, W; Ma, CW, 2001) | 0.31 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.67) | 18.2507 |
| 2000's | 8 (26.67) | 29.6817 |
| 2010's | 18 (60.00) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (37.20) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 1 (3.23%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 30 (96.77%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||