Proteins > G-protein coupled receptor 84
Page last updated: 2024-08-07 20:42:54
G-protein coupled receptor 84
A G-protein coupled receptor 84 that is encoded in the genome of human. [PRO:WCB, UniProtKB:Q9NQS5]
Synonyms
Inflammation-related G-protein coupled receptor EX33
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
Compounds (15)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| 3,3'-diindolylmethane | Homo sapiens (human) | Kb | 0.8800 | 1 | 1 |
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.Journal of medicinal chemistry, , 03-12, Volume: 63, Issue:5, 2020
[no title available]Journal of medicinal chemistry, , 05-11, Volume: 60, Issue:9, 2017
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.Journal of medicinal chemistry, , 03-12, Volume: 63, Issue:5, 2020
[no title available]Journal of medicinal chemistry, , 05-11, Volume: 60, Issue:9, 2017
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.Journal of medicinal chemistry, , 03-12, Volume: 63, Issue:5, 2020
[no title available]Journal of medicinal chemistry, , 05-11, Volume: 60, Issue:9, 2017
Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists.Journal of medicinal chemistry, , 12-24, Volume: 63, Issue:24, 2020
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.Journal of medicinal chemistry, , 03-12, Volume: 63, Issue:5, 2020
Succinct synthesis of saturated hydroxy fatty acids and MedChemComm, , Jun-01, Volume: 8, Issue:6, 2017
Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists.Journal of medicinal chemistry, , 12-24, Volume: 63, Issue:24, 2020
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.Journal of medicinal chemistry, , 03-12, Volume: 63, Issue:5, 2020
Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists.Journal of medicinal chemistry, , 12-24, Volume: 63, Issue:24, 2020
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.Journal of medicinal chemistry, , 03-12, Volume: 63, Issue:5, 2020
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.Journal of medicinal chemistry, , 03-12, Volume: 63, Issue:5, 2020
Succinct synthesis of saturated hydroxy fatty acids and MedChemComm, , Jun-01, Volume: 8, Issue:6, 2017
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights.Journal of medicinal chemistry, , 03-12, Volume: 63, Issue:5, 2020
Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists.Journal of medicinal chemistry, , 12-24, Volume: 63, Issue:24, 2020
Succinct synthesis of saturated hydroxy fatty acids and MedChemComm, , Jun-01, Volume: 8, Issue:6, 2017
Enables
This protein enables 1 target(s):
| Target | Category | Definition |
|---|
| urotensin II receptor activity | molecular function | Combining with urotensin II to initiate a change in cell activity. [GOC:mah, PMID:15102493] |
Located In
This protein is located in 3 target(s):
| Target | Category | Definition |
|---|
| plasma membrane | cellular component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| specific granule membrane | cellular component | The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase. [GOC:bf, PMID:7334549] |
| tertiary granule membrane | cellular component | The lipid bilayer surrounding a tertiary granule. [GOC:BHF, GOC:mah, GOC:rl, PMID:12070036] |
Active In
This protein is active in 1 target(s):
| Target | Category | Definition |
|---|
| plasma membrane | cellular component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
Part Of
This protein is part of 1 target(s):
| Target | Category | Definition |
|---|
| receptor complex | cellular component | Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [GOC:go_curators] |
Involved In
This protein is involved in 2 target(s):
| Target | Category | Definition |
|---|
| biological_process | biological process | A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. [GOC:pdt] |
| neuropeptide signaling pathway | biological process | A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. [GOC:mah, ISBN:0815316194] |