Page last updated: 2024-08-07 15:33:18
Papain
[no definition available]
Synonyms
EC 3.4.22.2;
Papaya proteinase I;
PPI
Research
Bioassay Publications (15)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
Compounds (22)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| benzophenone | Carica papaya (papaya) | IC50 | 3,465.0000 | 1 | 1 |
| 9,10-phenanthrenequinone | Carica papaya (papaya) | IC50 | 91.0000 | 1 | 1 |
| 1,4-naphthoquinone | Carica papaya (papaya) | IC50 | 29.0000 | 1 | 1 |
| isoquinoline-1,3,4-trione | Carica papaya (papaya) | IC50 | 5.0000 | 1 | 1 |
| 1,2-naphthoquinone | Carica papaya (papaya) | IC50 | 120.0000 | 1 | 1 |
| aloxistatin | Carica papaya (papaya) | Ki | 52.0000 | 1 | 1 |
| leupeptin | Carica papaya (papaya) | IC50 | 0.0022 | 1 | 1 |
| n-(n-(3-carboxyoxirane-2-carbonyl)leucyl)isoamylamine | Carica papaya (papaya) | Ki | 2.4000 | 1 | 1 |
| e 64 | Carica papaya (papaya) | IC50 | 0.0187 | 3 | 3 |
| e 64 | Carica papaya (papaya) | Ki | 5.0800 | 1 | 1 |
| 2-methoxystypandrone | Carica papaya (papaya) | IC50 | 23.0000 | 1 | 1 |
| miltirone | Carica papaya (papaya) | IC50 | 88.0000 | 1 | 1 |
| cryptotanshinone | Carica papaya (papaya) | IC50 | 89.8000 | 1 | 1 |
| tanshinone ii a | Carica papaya (papaya) | IC50 | 122.0000 | 1 | 1 |
| chrysene-1,4-dione | Carica papaya (papaya) | IC50 | 18.0000 | 1 | 1 |
| 1-(2-Naphthylmethyl)-2,3-dioxo-indoline-5-carboxamide | Carica papaya (papaya) | IC50 | 11.0000 | 1 | 1 |
| guttiferone a | Carica papaya (papaya) | IC50 | 1.9000 | 1 | 1 |
| 6-(3,5-difluoroanilino)-9-ethyl-2-purinecarbonitrile | Carica papaya (papaya) | IC50 | 0.0447 | 1 | 1 |
| 9-(3,5-difluorophenyl)-6-(ethylamino)-2-purinecarbonitrile | Carica papaya (papaya) | IC50 | 0.0331 | 1 | 1 |
| grassystatin a | Carica papaya (papaya) | IC50 | 10.0000 | 1 | 1 |
Drugs with Other Measurements
Squaric acid/4-aminoquinoline conjugates: novel potent antiplasmodial agents.European journal of medicinal chemistry, , Volume: 69, 2013
Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors.Journal of medicinal chemistry, , Aug-08, Volume: 56, Issue:15, 2013
Aza vinyl sulfones: synthesis and evaluation as antiplasmodial agents.Bioorganic & medicinal chemistry, , Dec-15, Volume: 19, Issue:24, 2011
Natural polyprenylated benzophenones inhibiting cysteine and serine proteases.European journal of medicinal chemistry, , Volume: 44, Issue:3, 2009