Compounds > 2'-deoxy-5'-adenosine monophosphate
Page last updated: 2024-09-21

2'-deoxy-5'-adenosine monophosphate

Description

2'-deoxy-5'-adenosine monophosphate: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

2'-deoxyadenosine 5'-monophosphate : A purine 2'-deoxyribonucleoside 5'-monophosphate having adenine as the nucleobase. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID12599
CHEMBL ID1206239
CHEBI ID17713
SCHEMBL ID48174
MeSH IDM0060220

Synonyms (84)

Synonym
einecs 211-503-1
vfr8i97orm ,
adenosine, 2'-deoxy-, 5'-(dihydrogen phosphate)
unii-vfr8i97orm
CHEMBL1206239
2'-deoxyadenosine 5'-(dihydrogen phosphate)
CHEBI:17713 ,
MLS000069642
2'-deoxy-5'-adenosine monophosphate
smr000058246
[(2r,3s,5r)-5-(6-aminopurin-9-yl)-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
2'-deoxyadenosine-5'-monophosphate
d-amp
2'-deoxyadenosine monophosphate
nsc-82625
2'-deoxyadenylic acid
deoxy-amp
nsc-77680
deoxy-5'-adenylic acid
deoxyadenosine 5'-monophosphate
deoxyadenosine 5'-phosphate
5'-adenylic acid, 2'-deoxy-
2'-deoxy-amp
2'-deoxy-5'-adenylic acid
PDA ,
9h-purin-6-amine, 9-(2-deoxy-5-o-phosphono-beta-d-erythro-pentofuranosyl)-
2'-deoxy-5'-amp
adenosine, 2'-deoxy-, 5'-(dihydrogen phosphate) (6ci,8ci)
5'-adenylic acid, 2'-deoxy- (9ci)
deoxyadenosine-phosphate
C00360
653-63-4
2'-damp
deoxyadenosine monophosphate
DAMP ,
2'-deoxyadenosine 5'-monophosphate
deoxyadenylic acid
2'-deoxyadenosine 5'-phosphate
2'-deoxyadenosine 5'-monophosphate, sigma grade, 98-100%
D5M ,
[(2r,3s,5r)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
pda (van)
nsc 82625
BMSE000250
adenosine, 2'-deoxy-, 5'-(dihydrogen phosphate) (8ci)
nsc 77680
54509-79-4
NCGC00247026-01
[(3s,2r,5r)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosp hate
HMS2232E10
S3248
c10h14n5o6p
2'-deoxyadenosine-5'-phosphoric acid
AKOS015896800
HG1052
2'-deoxyadenosine-5-monophosphate free acid
gtpl5120
{[(2r,3s,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid
5'-damp
SCHEMBL48174
2'-deoxyadenosine-5'-monophosphate free acid
W-203418
((2r,3s,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
2'-deoxyadenosine-5'-monophosphate, free acid
mfcd00005753
2-deoxyadenosine-5-monophosphate
AS-59095
2_-deoxyadenosine 5_-monophosphate
deoxyadenylate
2'-deoxyadenosine-5'-phosphate
2'-deoxyadenylate
2'-deoxy-adenosine 5'-phosphoric acid
2'-deoxy-5'-adenylate
deoxy-5'-adenylate
2'-deoxy-adenosine 5'-phosphorate
HY-W016009
Q1874427
CS-W016725
4-dimethylaminobut-2-ynoic acid hydrochloride
desoxyadenosinmonophosphat
2 INVERTED EXCLAMATION MARKA-DEOXYADENOSINE -5 INVERTED EXCLAMATION MARKA-MONOPHOSPHATE FREE ACID
2'-deoxyadenosine 5'monophosphate
DTXSID901034859
BP-58811

Roles (1)

RoleDescription
fundamental metaboliteAny metabolite produced by all living cells.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
2'-deoxyadenosine 5'-phosphate
purine 2'-deoxyribonucleoside 5'-monophosphate
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (22)

2'-deoxy-5'-adenosine monophosphate is involved in 22 pathway(s), involving a total of 803 unique proteins and 1864 unique compounds

PathwayProteinsCompounds
Purine Metabolism3766
Adenosine Deaminase Deficiency3766
Adenylosuccinate Lyase Deficiency3766
Gout or Kelley-Seegmiller Syndrome3766
Lesch-Nyhan Syndrome (LNS)3766
Molybdenum Cofactor Deficiency3766
Xanthine Dehydrogenase Deficiency (Xanthinuria)3766
Purine Nucleoside Phosphorylase Deficiency3766
AICA-Ribosiduria3766
Azathioprine Action Pathway4782
Mercaptopurine Action Pathway4780
Thioguanine Action Pathway4781
Xanthinuria Type I3766
Xanthinuria Type II3766
Adenine Phosphoribosyltransferase Deficiency (APRT)3766
Mitochondrial DNA Depletion Syndrome-33766
Myoadenylate Deaminase Deficiency3766
Mitochondrial DNA Depletion Syndrome3566
Purine nucleotides and Nucleosides metabolism ( Purine nucleotides and Nucleosides metabolism )10577
ATP + dAMP = ADP + dADP ( Purine nucleotides and Nucleosides metabolism )44
The impact of Nsp14 on metabolism (COVID-19 Disease Map)084
Biochemical pathways: part I0466

Protein Targets (12)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, Beta-lactamaseEscherichia coli K-12Potency0.56230.044717.8581100.0000AID485294
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency79.43280.631035.7641100.0000AID504339
acid sphingomyelinaseHomo sapiens (human)Potency31.622814.125424.061339.8107AID504937
TDP1 proteinHomo sapiens (human)Potency2.78760.000811.382244.6684AID686978; AID686979
IDH1Homo sapiens (human)Potency10.32250.005210.865235.4813AID686970
chromobox protein homolog 1Homo sapiens (human)Potency44.66840.006026.168889.1251AID540317
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency25.92900.00419.984825.9290AID504444
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency14.12540.050127.073689.1251AID588590
gemininHomo sapiens (human)Potency25.92900.004611.374133.4983AID624296
Alpha-synucleinHomo sapiens (human)Potency14.12540.56239.398525.1189AID652106
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Other Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (83)

Processvia Protein(s)Taxonomy
ADP biosynthetic processAdenylate kinase isoenzyme 1Homo sapiens (human)
nucleoside triphosphate biosynthetic processAdenylate kinase isoenzyme 1Homo sapiens (human)
nucleobase-containing small molecule interconversionAdenylate kinase isoenzyme 1Homo sapiens (human)
AMP metabolic processAdenylate kinase isoenzyme 1Homo sapiens (human)
ATP metabolic processAdenylate kinase isoenzyme 1Homo sapiens (human)
nucleoside monophosphate phosphorylationAdenylate kinase isoenzyme 1Homo sapiens (human)
calcium ion homeostasisAlpha-synucleinHomo sapiens (human)
negative regulation of transcription by RNA polymerase IIAlpha-synucleinHomo sapiens (human)
microglial cell activationAlpha-synucleinHomo sapiens (human)
positive regulation of receptor recyclingAlpha-synucleinHomo sapiens (human)
positive regulation of neurotransmitter secretionAlpha-synucleinHomo sapiens (human)
negative regulation of protein kinase activityAlpha-synucleinHomo sapiens (human)
fatty acid metabolic processAlpha-synucleinHomo sapiens (human)
neutral lipid metabolic processAlpha-synucleinHomo sapiens (human)
phospholipid metabolic processAlpha-synucleinHomo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic processAlpha-synucleinHomo sapiens (human)
mitochondrial membrane organizationAlpha-synucleinHomo sapiens (human)
adult locomotory behaviorAlpha-synucleinHomo sapiens (human)
response to xenobiotic stimulusAlpha-synucleinHomo sapiens (human)
response to iron(II) ionAlpha-synucleinHomo sapiens (human)
regulation of phospholipase activityAlpha-synucleinHomo sapiens (human)
negative regulation of platelet-derived growth factor receptor signaling pathwayAlpha-synucleinHomo sapiens (human)
regulation of glutamate secretionAlpha-synucleinHomo sapiens (human)
regulation of dopamine secretionAlpha-synucleinHomo sapiens (human)
synaptic vesicle exocytosisAlpha-synucleinHomo sapiens (human)
synaptic vesicle primingAlpha-synucleinHomo sapiens (human)
regulation of transmembrane transporter activityAlpha-synucleinHomo sapiens (human)
negative regulation of microtubule polymerizationAlpha-synucleinHomo sapiens (human)
receptor internalizationAlpha-synucleinHomo sapiens (human)
protein destabilizationAlpha-synucleinHomo sapiens (human)
response to magnesium ionAlpha-synucleinHomo sapiens (human)
negative regulation of transporter activityAlpha-synucleinHomo sapiens (human)
response to lipopolysaccharideAlpha-synucleinHomo sapiens (human)
negative regulation of monooxygenase activityAlpha-synucleinHomo sapiens (human)
positive regulation of peptidyl-serine phosphorylationAlpha-synucleinHomo sapiens (human)
response to type II interferonAlpha-synucleinHomo sapiens (human)
cellular response to oxidative stressAlpha-synucleinHomo sapiens (human)
SNARE complex assemblyAlpha-synucleinHomo sapiens (human)
positive regulation of SNARE complex assemblyAlpha-synucleinHomo sapiens (human)
regulation of locomotionAlpha-synucleinHomo sapiens (human)
dopamine biosynthetic processAlpha-synucleinHomo sapiens (human)
mitochondrial ATP synthesis coupled electron transportAlpha-synucleinHomo sapiens (human)
regulation of macrophage activationAlpha-synucleinHomo sapiens (human)
positive regulation of apoptotic processAlpha-synucleinHomo sapiens (human)
negative regulation of apoptotic processAlpha-synucleinHomo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic processAlpha-synucleinHomo sapiens (human)
negative regulation of neuron apoptotic processAlpha-synucleinHomo sapiens (human)
positive regulation of endocytosisAlpha-synucleinHomo sapiens (human)
negative regulation of exocytosisAlpha-synucleinHomo sapiens (human)
positive regulation of exocytosisAlpha-synucleinHomo sapiens (human)
regulation of long-term neuronal synaptic plasticityAlpha-synucleinHomo sapiens (human)
synaptic vesicle endocytosisAlpha-synucleinHomo sapiens (human)
synaptic vesicle transportAlpha-synucleinHomo sapiens (human)
positive regulation of inflammatory responseAlpha-synucleinHomo sapiens (human)
regulation of acyl-CoA biosynthetic processAlpha-synucleinHomo sapiens (human)
protein tetramerizationAlpha-synucleinHomo sapiens (human)
positive regulation of release of sequestered calcium ion into cytosolAlpha-synucleinHomo sapiens (human)
neuron apoptotic processAlpha-synucleinHomo sapiens (human)
dopamine uptake involved in synaptic transmissionAlpha-synucleinHomo sapiens (human)
negative regulation of dopamine uptake involved in synaptic transmissionAlpha-synucleinHomo sapiens (human)
negative regulation of serotonin uptakeAlpha-synucleinHomo sapiens (human)
regulation of norepinephrine uptakeAlpha-synucleinHomo sapiens (human)
negative regulation of norepinephrine uptakeAlpha-synucleinHomo sapiens (human)
excitatory postsynaptic potentialAlpha-synucleinHomo sapiens (human)
long-term synaptic potentiationAlpha-synucleinHomo sapiens (human)
positive regulation of inositol phosphate biosynthetic processAlpha-synucleinHomo sapiens (human)
negative regulation of thrombin-activated receptor signaling pathwayAlpha-synucleinHomo sapiens (human)
response to interleukin-1Alpha-synucleinHomo sapiens (human)
cellular response to copper ionAlpha-synucleinHomo sapiens (human)
cellular response to epinephrine stimulusAlpha-synucleinHomo sapiens (human)
positive regulation of protein serine/threonine kinase activityAlpha-synucleinHomo sapiens (human)
supramolecular fiber organizationAlpha-synucleinHomo sapiens (human)
negative regulation of mitochondrial electron transport, NADH to ubiquinoneAlpha-synucleinHomo sapiens (human)
positive regulation of glutathione peroxidase activityAlpha-synucleinHomo sapiens (human)
positive regulation of hydrogen peroxide catabolic processAlpha-synucleinHomo sapiens (human)
regulation of synaptic vesicle recyclingAlpha-synucleinHomo sapiens (human)
regulation of reactive oxygen species biosynthetic processAlpha-synucleinHomo sapiens (human)
positive regulation of protein localization to cell peripheryAlpha-synucleinHomo sapiens (human)
negative regulation of chaperone-mediated autophagyAlpha-synucleinHomo sapiens (human)
regulation of presynapse assemblyAlpha-synucleinHomo sapiens (human)
amyloid fibril formationAlpha-synucleinHomo sapiens (human)
synapse organizationAlpha-synucleinHomo sapiens (human)
chemical synaptic transmissionAlpha-synucleinHomo sapiens (human)
ADP biosynthetic processAdenylate kinase 2, mitochondrialHomo sapiens (human)
nucleobase-containing small molecule interconversionAdenylate kinase 2, mitochondrialHomo sapiens (human)
AMP metabolic processAdenylate kinase 2, mitochondrialHomo sapiens (human)
ATP metabolic processAdenylate kinase 2, mitochondrialHomo sapiens (human)
nucleoside monophosphate phosphorylationAdenylate kinase 2, mitochondrialHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (30)

Processvia Protein(s)Taxonomy
adenylate kinase activityAdenylate kinase isoenzyme 1Homo sapiens (human)
nucleoside diphosphate kinase activityAdenylate kinase isoenzyme 1Homo sapiens (human)
ATP bindingAdenylate kinase isoenzyme 1Homo sapiens (human)
nucleoside triphosphate adenylate kinase activityAdenylate kinase isoenzyme 1Homo sapiens (human)
fatty acid bindingAlpha-synucleinHomo sapiens (human)
phospholipase D inhibitor activityAlpha-synucleinHomo sapiens (human)
SNARE bindingAlpha-synucleinHomo sapiens (human)
magnesium ion bindingAlpha-synucleinHomo sapiens (human)
transcription cis-regulatory region bindingAlpha-synucleinHomo sapiens (human)
actin bindingAlpha-synucleinHomo sapiens (human)
protein kinase inhibitor activityAlpha-synucleinHomo sapiens (human)
copper ion bindingAlpha-synucleinHomo sapiens (human)
calcium ion bindingAlpha-synucleinHomo sapiens (human)
protein bindingAlpha-synucleinHomo sapiens (human)
phospholipid bindingAlpha-synucleinHomo sapiens (human)
ferrous iron bindingAlpha-synucleinHomo sapiens (human)
zinc ion bindingAlpha-synucleinHomo sapiens (human)
lipid bindingAlpha-synucleinHomo sapiens (human)
oxidoreductase activityAlpha-synucleinHomo sapiens (human)
kinesin bindingAlpha-synucleinHomo sapiens (human)
Hsp70 protein bindingAlpha-synucleinHomo sapiens (human)
histone bindingAlpha-synucleinHomo sapiens (human)
identical protein bindingAlpha-synucleinHomo sapiens (human)
alpha-tubulin bindingAlpha-synucleinHomo sapiens (human)
cysteine-type endopeptidase inhibitor activity involved in apoptotic processAlpha-synucleinHomo sapiens (human)
tau protein bindingAlpha-synucleinHomo sapiens (human)
phosphoprotein bindingAlpha-synucleinHomo sapiens (human)
molecular adaptor activityAlpha-synucleinHomo sapiens (human)
dynein complex bindingAlpha-synucleinHomo sapiens (human)
cuprous ion bindingAlpha-synucleinHomo sapiens (human)
adenylate kinase activityAdenylate kinase 2, mitochondrialHomo sapiens (human)
protein bindingAdenylate kinase 2, mitochondrialHomo sapiens (human)
ATP bindingAdenylate kinase 2, mitochondrialHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (26)

Processvia Protein(s)Taxonomy
outer dense fiberAdenylate kinase isoenzyme 1Homo sapiens (human)
cytosolAdenylate kinase isoenzyme 1Homo sapiens (human)
extracellular exosomeAdenylate kinase isoenzyme 1Homo sapiens (human)
cytoplasmAdenylate kinase isoenzyme 1Homo sapiens (human)
cytosolAdenylate kinase isoenzyme 1Homo sapiens (human)
platelet alpha granule membraneAlpha-synucleinHomo sapiens (human)
extracellular regionAlpha-synucleinHomo sapiens (human)
extracellular spaceAlpha-synucleinHomo sapiens (human)
nucleusAlpha-synucleinHomo sapiens (human)
cytoplasmAlpha-synucleinHomo sapiens (human)
mitochondrionAlpha-synucleinHomo sapiens (human)
lysosomeAlpha-synucleinHomo sapiens (human)
cytosolAlpha-synucleinHomo sapiens (human)
plasma membraneAlpha-synucleinHomo sapiens (human)
cell cortexAlpha-synucleinHomo sapiens (human)
actin cytoskeletonAlpha-synucleinHomo sapiens (human)
membraneAlpha-synucleinHomo sapiens (human)
inclusion bodyAlpha-synucleinHomo sapiens (human)
axonAlpha-synucleinHomo sapiens (human)
growth coneAlpha-synucleinHomo sapiens (human)
synaptic vesicle membraneAlpha-synucleinHomo sapiens (human)
perinuclear region of cytoplasmAlpha-synucleinHomo sapiens (human)
postsynapseAlpha-synucleinHomo sapiens (human)
supramolecular fiberAlpha-synucleinHomo sapiens (human)
protein-containing complexAlpha-synucleinHomo sapiens (human)
cytoplasmAlpha-synucleinHomo sapiens (human)
axon terminusAlpha-synucleinHomo sapiens (human)
neuronal cell bodyAlpha-synucleinHomo sapiens (human)
mitochondrial intermembrane spaceAdenylate kinase 2, mitochondrialHomo sapiens (human)
extracellular exosomeAdenylate kinase 2, mitochondrialHomo sapiens (human)
sperm mitochondrial sheathAdenylate kinase 2, mitochondrialHomo sapiens (human)
cytoplasmAdenylate kinase 2, mitochondrialHomo sapiens (human)
mitochondrionAdenylate kinase 2, mitochondrialHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (18)

Assay IDTitleYearJournalArticle
AID1743971Substrate activity at HIV1 reverse transcriptase assessed as incorporation of compound into growing DNA strand at 500 uM incubated for 1 hr using primer and template in presence of MgCl2 by gel based nucleotide incorporation assay2021Journal of medicinal chemistry, 01-14, Volume: 64, Issue:1
Tenofovir-Amino Acid Conjugates Act as Polymerase Substrates-Implications for Avoiding Cellular Phosphorylation in the Discovery of Nucleotide Analogues.
AID1186718Ratio of Kcat to Km for recombinant AK2 (unknown origin)2014Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
Synthesis of {[5-(adenin-9-yl)-2-furyl]methoxy}methyl phosphonic acid and evaluations against human adenylate kinases.
AID1186715Activity of recombinant AK1 (unknown origin) assessed as ADP formation by spectroscopic pyruvate kinase/lactate dehydrogenase coupled assay2014Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
Synthesis of {[5-(adenin-9-yl)-2-furyl]methoxy}methyl phosphonic acid and evaluations against human adenylate kinases.
AID1186716Activity of recombinant AK2 (unknown origin) assessed as ADP formation by spectroscopic pyruvate kinase/lactate dehydrogenase coupled assay2014Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
Synthesis of {[5-(adenin-9-yl)-2-furyl]methoxy}methyl phosphonic acid and evaluations against human adenylate kinases.
AID1186717Ratio of Kcat to Km for recombinant AK1 (unknown origin)2014Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17
Synthesis of {[5-(adenin-9-yl)-2-furyl]methoxy}methyl phosphonic acid and evaluations against human adenylate kinases.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (152)

TimeframeStudies, This Drug (%)All Drugs %
pre-199033 (21.71)18.7374
1990's35 (23.03)18.2507
2000's44 (28.95)29.6817
2010's36 (23.68)24.3611
2020's4 (2.63)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (0.65%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other154 (99.35%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
adenosine monophosphate[no description available]medium140adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
adefovir[no description available]medium106-aminopurines;
ether;
phosphonic acids		antiviral drug;
DNA synthesis inhibitor;
drug metabolite;
HIV-1 reverse transcriptase inhibitor;
nephrotoxic agent
tenofovir[no description available]medium20nucleoside analogue;
phosphonic acids		antiviral drug;
drug metabolite;
HIV-1 reverse transcriptase inhibitor
2'-deoxyadenosine[no description available]medium40purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
cyclosporine[no description available]medium10
betadex[no description available]medium10cyclodextrin
2'-deoxyadenosine triphosphate[no description available]medium1002'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
deoxycytidine monophosphate[no description available]medium1902'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
mouse metabolite
2'-deoxyguanosine 5'-phosphate[no description available]medium260deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
mouse metabolite
adenosine diphosphate ribose[no description available]medium10ADP-sugarEscherichia coli metabolite;
mouse metabolite
uracil[no description available]medium30pyrimidine nucleobase;
pyrimidone		allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite
guanosine triphosphate[no description available]medium20guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor
deoxyguanosine[no description available]medium30purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
8-hydroxy-2'-deoxyguanosine[no description available]medium20guanosinesbiomarker
8-oxodeoxyguanosine triphosphate[no description available]medium10purine 2'-deoxyribonucleoside 5'-triphosphatemutagen
8-hydroxyguanosine triphosphate[no description available]medium10
11,12-epoxy-5,8,14-eicosatrienoic acid[no description available]medium1011,12-EEThuman xenobiotic metabolite
8,9-epoxyeicosatrienoic acid[no description available]medium10EETmouse metabolite
5,6-epoxy-8,11,14-eicosatrienoic acid[no description available]medium10EETmouse metabolite
8,11,14-eicosatrienoic acid[no description available]medium10fatty acid 20:3;
long-chain fatty acid		fungal metabolite;
human metabolite;
nutraceutical
14,15-epoxy-5,8,11-eicosatrienoic acid[no description available]medium10long-chain fatty acid
phosphorus radioisotopes[no description available]medium50
adenine[no description available]medium906-aminopurines;
purine nucleobase		Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
thymidine monophosphate[no description available]medium180thymidine 5'-monophosphatefundamental metabolite
phosphoramidic acid[no description available]medium30phosphoric acid derivative
boron[no description available]medium10boron group element atom;
metalloid atom;
nonmetal atom		micronutrient
uridine[no description available]medium10uridinesdrug metabolite;
fundamental metabolite;
human metabolite
tyrosine[no description available]medium20amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
guanine[no description available]medium502-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
8-hydroxyguanine[no description available]medium10oxopurine
histidine[no description available]medium20amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
guanidinohydantoin[no description available]medium10guanidines;
imidazolidine-2,4-dione
hydantoins[no description available]medium20imidazolidine-2,4-dione
singlet oxygen[no description available]medium20chalcogen;
monoatomic oxygen;
nonmetal atom		macronutrient
lumazine[no description available]medium202,4-dihydroxypteridine
pteridines[no description available]medium20azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
pteridines
cytidine[no description available]medium10cytidinesEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
adenosine[no description available]medium40adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
1-methyladenosine[no description available]medium10methyladenosinehuman metabolite
3-methylcytidine[no description available]medium10methylcytidine
silver[no description available]medium10copper group element atom;
elemental silver		Escherichia coli metabolite
manganese[no description available]medium40elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
tromethamine[no description available]medium10primary amino compound;
triol		buffer
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
cytidine monophosphate[no description available]medium30cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
uridine monophosphate[no description available]medium10pyrimidine ribonucleoside 5'-monophosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
guanosine monophosphate[no description available]medium40guanosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		biomarker;
Escherichia coli metabolite;
metabolite;
mouse metabolite
hydroxylamine[no description available]medium10hydroxylaminesalgal metabolite;
bacterial xenobiotic metabolite;
EC 1.1.3.13 (alcohol oxidase) inhibitor;
EC 4.2.1.22 (cystathionine beta-synthase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
nitric oxide donor;
nucleophilic reagent
nad[no description available]medium10organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
platinum[no description available]medium10elemental platinum;
nickel group element atom;
platinum group metal atom
norharman[no description available]medium10beta-carbolines;
mancude organic heterotricyclic parent		fungal metabolite;
marine metabolite
harmine[no description available]medium10harmala alkaloidanti-HIV agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
metabolite
deuterium oxide[no description available]medium10deuterated compound;
water		NMR solvent
cacodylic acid[no description available]medium10organoarsenic compoundxenobiotic metabolite
oligonucleotides[no description available]medium20
ribose[no description available]medium20D-ribose;
ribopyranose
cobamamide[no description available]medium10
cetyltrimethylammonium ion[no description available]medium10quaternary ammonium ion
dimethyldioctadecylammonium[no description available]medium10
deoxyguanosine triphosphate[no description available]medium20deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-triphosphate		Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
inosinic acid[no description available]medium10inosine phosphate;
purine ribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
cytosine[no description available]medium30aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxycytidine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
angiotensin i[no description available]medium10angiotensin;
peptide zwitterion		human metabolite;
neurotransmitter agent
hydrogen sulfite[no description available]medium10sulfur oxoanionhuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
sulfites[no description available]medium10divalent inorganic anion;
sulfur oxide;
sulfur oxoanion
propidium[no description available]medium10phenanthridines;
quaternary ammonium ion		fluorochrome;
intercalator
cytochrome c-t[no description available]medium10
formaldehyde[no description available]medium10aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
deoxyribose[no description available]medium30deoxypentosehuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
lysine[no description available]medium10aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
guanosine[no description available]medium20guanosines;
purines D-ribonucleoside		fundamental metabolite
8-hydroxyguanosine[no description available]medium20purine nucleoside
adenosine diphosphate[no description available]medium10adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
2'-deoxy-3'-adenosine monophosphate[no description available]medium102'-deoxyadenosine phosphate;
purine 2'-deoxyribonucleoside 3'-monophosphate
hydrogen[no description available]medium10elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
pyrene[no description available]medium10ortho- and peri-fused polycyclic arenefluorescent probe;
persistent organic pollutant
lithium perchlorate[no description available]medium10
acetone[no description available]medium20ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
aspartic acid[no description available]medium20aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
sulfur[no description available]medium10chalcogen;
nonmetal atom		macronutrient
thymidine 5'-triphosphate[no description available]medium30pyrimidine 2'-deoxyribonucleoside 5'-triphosphate;
thymidine phosphate		Escherichia coli metabolite;
mouse metabolite
o(6)-methyldeoxyguanylic acid[no description available]medium10
inosine[no description available]medium10inosines;
purines D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2'-deoxyadenosine triphosphate[no description available]medium102'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-diphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite
thymidine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
edetic acid[no description available]medium10ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
isoguanine[no description available]medium10oxopurine
2-hydroxydeoxyadenosine triphosphate[no description available]medium10purine 2'-deoxyribonucleoside 5'-triphosphate
hydroxyl radical[no description available]medium30oxygen hydride;
oxygen radical;
reactive oxygen species
cysteamine[no description available]medium10amine;
thiol		geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent
glycine[no description available]medium10alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide[no description available]medium10epoxideintercalator
chlorine[no description available]medium10halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
guanidine[no description available]medium10carboxamidine;
guanidines;
one-carbon compound
adamantane[no description available]medium10adamantanes;
polycyclic alkane
2,4-diamino-5-adamantyl-6-methylpyrimidine[no description available]medium10
nickel[no description available]medium20metal allergen;
nickel group element atom		epitope;
micronutrient
cladribine[no description available]medium10organochlorine compound;
purine 2'-deoxyribonucleoside		antineoplastic agent;
immunosuppressive agent
iodoacetamide[no description available]medium20
thymine[no description available]medium20pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite
tamoxifen[no description available]medium10stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
glutaral[no description available]medium10dialdehydecross-linking reagent;
disinfectant;
fixative
spermine[no description available]medium10polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent
thymine glycol[no description available]medium10hydroxypyrimidine
arginyl-glycyl-aspartic acid[no description available]medium10oligopeptide
serine[no description available]medium10L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
monoammonium molybdate[no description available]medium10ammonium saltpoison
ethidium[no description available]medium10phenanthridinesfluorochrome;
intercalator
molybdenum[no description available]medium10chromium group element atommicronutrient
iridium[no description available]medium10cobalt group element atom;
platinum group metal atom
hexachloroiridic acid[no description available]medium10
1,3-butadiene[no description available]medium10butadienecarcinogenic agent;
mutagen
dibenzo(a,l)pyrene[no description available]medium10ortho- and peri-fused polycyclic arenehuman metabolite;
mutagen
melphalan[no description available]medium10L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
glucose, (beta-d)-isomer[no description available]medium20D-glucopyranoseepitope;
mouse metabolite
acteoside[no description available]medium20catechols;
cinnamate ester;
disaccharide derivative;
glycoside;
polyphenol		anti-inflammatory agent;
antibacterial agent;
antileishmanial agent;
neuroprotective agent;
plant metabolite
iridoids[no description available]medium10
methyl 4,6-o-(1-carboxyethylidene)galactopyranoside[no description available]medium10
1,n(6)-ethenodeoxyadenosine[no description available]medium10purines
pyrimidine dimers[no description available]medium10
6-nitrochrysene[no description available]medium10carbopolycyclic compound
dehydroretronecine[no description available]medium10
monocrotaline[no description available]medium10pyrrolizidine alkaloid
retronecine[no description available]medium10pyrrolizines
guanosine 5'-o-(3-thiotriphosphate)[no description available]medium10nucleoside triphosphate analogue
8-bromo cyclic adenosine monophosphate[no description available]medium103',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
organobromine compound		antidepressant;
protein kinase agonist
isopentenyladenosine[no description available]medium10N-ribosyl-N(6)-isopentenyladenine;
nucleoside analogue		antineoplastic agent;
plant growth regulator;
plant metabolite
pyridine[no description available]medium10azaarene;
mancude organic heteromonocyclic parent;
monocyclic heteroarene;
pyridines		environmental contaminant;
NMR chemical shift reference compound
1-ethyl-3-(3-dimethylaminoethyl)carbodiimide[no description available]medium10
carbodiimides[no description available]medium10carbodiimide
histidylhistidine[no description available]medium10dipeptideMycoplasma genitalium metabolite
2',3'-cyclic amp[no description available]medium102',3'-cyclic purine nucleotideEscherichia coli metabolite
2'-5'-oligoadenylate trimer[no description available]medium10
angoroside c[no description available]medium10
dimethylformamide[no description available]medium10formamides;
volatile organic compound		geroprotector;
hepatotoxic agent;
polar aprotic solvent
titanium[no description available]medium10titanium group element atom
aphidicolin[no description available]medium20tetracyclic diterpenoidantimicrobial agent;
antimitotic;
antineoplastic agent;
antiviral drug;
apoptosis inducer;
Aspergillus metabolite;
DNA synthesis inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
fungal metabolite
thionine[no description available]medium10
benzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
1-butanol[no description available]medium10alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol		human metabolite;
mouse metabolite;
protic solvent
europium[no description available]medium10f-block element atom;
lanthanoid atom
2'-deoxyadenylyl-(3'-5')-2'-deoxyadenosine[no description available]medium10nucleoside analogue;
purines
adenylyl imidodiphosphate[no description available]medium10adenosine 5'-phosphate
ozone[no description available]medium10elemental molecule;
gas molecular entity;
reactive oxygen species;
triatomic oxygen		antiseptic drug;
disinfectant;
electrophilic reagent;
greenhouse gas;
mutagen;
oxidising agent;
tracer
phosphorus[no description available]medium10monoatomic phosphorus;
nonmetal atom;
pnictogen		macronutrient
tobramycin[no description available]medium10amino cyclitol glycosideantibacterial agent;
antimicrobial agent;
toxin
cysteine[no description available]medium10cysteiniumfundamental metabolite
metallothionein[no description available]medium10
chloroethylene oxide[no description available]medium10organochlorine compound
vinyl chloride[no description available]medium10chloroethenes;
gas molecular entity;
monohaloethene		carcinogenic agent
ethylene oxide[no description available]medium10gas molecular entity;
oxacycle;
saturated organic heteromonocyclic parent		allergen;
mouse metabolite;
mutagen
7-n-(2-oxoethyl)guanine[no description available]medium10
n-amylamine[no description available]medium10primary aliphatic amine
diethylstilbestrol quinone[no description available]medium10
diethylstilbestrol[no description available]medium10olefinic compound;
polyphenol		antifungal agent;
antineoplastic agent;
autophagy inducer;
calcium channel blocker;
carcinogenic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
endocrine disruptor;
xenoestrogen
dienestrol[no description available]medium10
mercaptoethanol[no description available]medium10alkanethiol;
primary alcohol		geroprotector
alpha-ketoglutaric acid[no description available]low00oxo dicarboxylic acidfundamental metabolite
beta-alanine[no description available]low00amino acid zwitterion;
beta-amino acid		agonist;
fundamental metabolite;
human metabolite;
inhibitor;
neurotransmitter
betaine[no description available]low00amino-acid betaine;
glycine derivative		fundamental metabolite
betaine hydrochloride[no description available]low00quaternary ammonium ionfundamental metabolite
citric acid, anhydrous[no description available]low00tricarboxylic acidantimicrobial agent;
chelator;
food acidity regulator;
fundamental metabolite
malic acid[no description available]low002-hydroxydicarboxylic acid;
C4-dicarboxylic acid		food acidity regulator;
fundamental metabolite
cysteine[no description available]low00alpha-amino acid;
amino acid zwitterion;
polar amino acid;
sulfur-containing amino acid		fundamental metabolite
alanine[no description available]low00alpha-amino acid;
amino acid zwitterion		fundamental metabolite
3-phosphoglycerate[no description available]low00monophosphoglyceric acid;
tetronic acid derivative		algal metabolite;
fundamental metabolite
glyceraldehyde[no description available]low00aldotriosefundamental metabolite
glyceric acid[no description available]low00trionic acidfundamental metabolite
glycolaldehyde[no description available]low00glycolaldehydesfundamental metabolite;
human metabolite
thioctic acid[no description available]low00dithiolanes;
heterocyclic fatty acid;
thia fatty acid		fundamental metabolite;
geroprotector
phenylpyruvic acid[no description available]low002-oxo monocarboxylic acidchromogenic compound;
EC 6.4.1.1 (pyruvate carboxylase) inhibitor;
fundamental metabolite
phosphoenolpyruvate[no description available]low00carboxyalkyl phosphate;
monocarboxylic acid		fundamental metabolite
putrescine[no description available]low00alkane-alpha,omega-diamineantioxidant;
fundamental metabolite
pyruvic acid[no description available]low002-oxo monocarboxylic acidcofactor;
fundamental metabolite
spermidine[no description available]low00polyazaalkane;
triamine		autophagy inducer;
fundamental metabolite;
geroprotector
succinic acid[no description available]low00alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent
isocitric acid[no description available]low00secondary alcohol;
tricarboxylic acid		fundamental metabolite
nadp[no description available]low00NADPfundamental metabolite
alanine[no description available]low00alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
uridine diphosphate glucose[no description available]low00UDP-D-glucosefundamental metabolite
pseudouridine[no description available]low00pseudouridinesfundamental metabolite
uridine diphosphate xylose[no description available]low00UDP-sugarfundamental metabolite
serum p-component[no description available]low00citrate anion;
tricarboxylic acid trianion		fundamental metabolite
6-phosphogluconic acid[no description available]low00gluconic acid phosphatefundamental metabolite
homocysteine[no description available]low00amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
biotin[no description available]low00biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
s-adenosylhomocysteine[no description available]low00adenosines;
amino acid zwitterion;
homocysteine derivative;
homocysteines;
organic sulfide		cofactor;
EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor;
EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor;
epitope;
fundamental metabolite
aconitic acid[no description available]low00aconitic acidfundamental metabolite
acetyl coenzyme a[no description available]low00acyl-CoAacyl donor;
coenzyme;
effector;
fundamental metabolite
fumaric acid[no description available]low00butenedioic acidfood acidity regulator;
fundamental metabolite;
geroprotector
riboflavin[no description available]low00flavin;
vitamin B2		anti-inflammatory agent;
antioxidant;
cofactor;
Escherichia coli metabolite;
food colouring;
fundamental metabolite;
human urinary metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite
mannose 1-phosphate[no description available]low00mannose phosphatefundamental metabolite;
human metabolite
adenosine triphosphate[no description available]low00nucleoside 5'-triphoshate(4-)cofactor;
fundamental metabolite;
human metabolite
adenosine diphosphate[no description available]low00nucleoside 5'-diphosphate(3-)fundamental metabolite;
human metabolite
adenosine monophosphate[no description available]low00nucleoside 5'-monophosphate(2-)cofactor;
fundamental metabolite;
human metabolite
hypoxanthine[no description available]low00nucleobase analogue;
oxopurine;
purine nucleobase		fundamental metabolite
inosine diphosphate[no description available]low00inosine phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite
deoxyinosine monophosphate[no description available]low00deoxyinosine phosphate;
purine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
8-hydroxydeoxyguanosine 5'-monophosphate[no description available]low00purine 2'-deoxyribonucleoside 5'-monophosphate
ConditionIndicatedRelationship StrengthStudiesTrials
2019 Novel Coronavirus Disease0low10
2019 Novel Coronavirus Infection0low10
2019-nCoV Disease0low10
2019-nCoV Infection0low10
Abnormalities, Drug-Induced0low10
Adenocarcinoma0low10
Adenocarcinoma, Basal Cell0low10
Adenocarcinoma, Granular Cell0low10
Adenocarcinoma, Oxyphilic0low10
Adenocarcinoma, Tubular0low10
Adenoma, Malignant0low10
Cancer of Lung0low10
Cancer of the Lung0low10
Carcinoma, Cribriform0low10
Carcinoma, Granular Cell0low10
Carcinoma, Tubular0low10
Coronavirus Disease 20190low10
Coronavirus Disease-190low10
COVID-190low10
COVID-19 Pandemic0low10
COVID-19 Pandemics0low10
COVID-19 Virus Disease0low10
COVID-19 Virus Infection0low10
COVID190low10
Drug-Induced Abnormalities0low10
Eye Abnormalities0low10
Grippe0low10
HIV0low10
Human Flu0low10
Human Influenza0low10
Inflammation0low10
Influenza0low10
Influenza in Humans0low10
Influenza, Human0low10
Innate Inflammatory Response0low10
Kaposi Disease0low10
Kaposi's Disease0low10
Leukemia, Lymphocytic0low10
Leukemia, Lymphoid0low10
Libman-Sacks Disease0low10
Lung Cancer0low10
Lung Neoplasms0low10
Lupus Erythematosus Disseminatus0low10
Lupus Erythematosus, Systemic0low10
Lymphocytic Leukemia0low10
Lymphoid Leukemia0low10
Neoplasms, Lung0low10
Neoplasms, Pulmonary0low10
Pregnancy0low10
Pulmonary Cancer0low10
Pulmonary Neoplasms0low10
SARS Coronavirus 2 Infection0low10
SARS-CoV-2 Infection0low10
Sensitivity and Specificity0low40
Systemic Lupus Erythematosus0low10
Viral Diseases0low10
Viral Infections0low10
Virus Diseases0low10
Virus Infections0low10
Xeroderma Pigmentosum0low10