Page last updated: 2024-08-07 19:36:39
Deoxynucleoside kinase
A thymidine kinase 2, mitochondrial that is encoded in the genome of fruit fly. [OMA:Q9XZT6, PRO:DNx]
Synonyms
EC 2.7.1.145;
Deoxyribonucleoside kinase;
Dm-dNK;
Multispecific deoxynucleoside kinase
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| cytarabine | Drosophila melanogaster (fruit fly) | IC50 | 5,319.0000 | 2 | 2 |
| thymine arabinoside | Drosophila melanogaster (fruit fly) | IC50 | 65.0000 | 2 | 2 |
| sorivudine | Drosophila melanogaster (fruit fly) | IC50 | 28.0000 | 1 | 1 |
| 9-arabinofuranosylguanine | Drosophila melanogaster (fruit fly) | IC50 | 500.0000 | 1 | 1 |
Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity.Bioorganic & medicinal chemistry, , Apr-15, Volume: 15, Issue:8, 2007
Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors.Bioorganic & medicinal chemistry letters, , May-21, Volume: 11, Issue:10, 2001
Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity.Bioorganic & medicinal chemistry, , Apr-15, Volume: 15, Issue:8, 2007
Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors.Bioorganic & medicinal chemistry letters, , May-21, Volume: 11, Issue:10, 2001