ifosfamide has been researched along with Sensitivity and Specificity in 29 studies
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "26 women, affected by locally advanced cervical cancer and triaged for surgery after NACT, were submitted to three cycles of neoadjuvant chemotherapy." | 2.77 | Is magnetic resonance imaging useful in early evaluation of women on neoadjuvant chemotherapy for locally advanced cervical cancer? ( Cittadini, G; Costantini, S; Mammoliti, S; Marchiolè, P; Moioli, M; Sala, P; Valenzano Menada, M, 2012) |
| " This method was applied to a comparative pharmacokinetic study of 4-OHIFO from IFO and three derivatives RXIFO in mice." | 1.42 | Simultaneous quantification of preactivated ifosfamide derivatives and of 4-hydroxyifosfamide by high performance liquid chromatography-tandem mass spectrometry in mouse plasma and its application to a pharmacokinetic study. ( Chapuis, H; Couvreur, P; Daudigeos-Dubus, E; Deroussent, A; Desmaële, D; Durand, S; Le Dret, L; Maury, A; Paci, A; Skarbek, C, 2015) |
| "Nodal relapse is also associated with a high mortality rate." | 1.40 | Diagnosis and treatment of lymph node metastases in pediatric rhabdomyosarcoma in the Netherlands: a retrospective analysis. ( Heij, HA; Merks, JH; Spronk, P; Terwisscha van Scheltinga, CE; van Baren, R; van Noesel, MM; van Rosmalen, J; Wijnen, MH; Wijnen, RM, 2014) |
| "Ifosfamide was analyzed in mouse kidney at 20 μm step size and was found to be accumulated in the inner medulla region." | 1.37 | Mass spectrometry imaging with high resolution in mass and space (HR(2) MSI) for reliable investigation of drug compound distributions on the cellular level. ( Guenther, S; Römpp, A; Spengler, B; Takats, Z, 2011) |
| "In patients with breast cancer, especially metastatic breast cancer, undergoing HDCT and ABMT, the presence of K19 is associated with a poor prognosis." | 1.29 | Clinical significance of bone marrow metastases as detected using the polymerase chain reaction in patients with breast cancer undergoing high-dose chemotherapy and autologous bone marrow transplantation. ( Elfenbein, GJ; Fields, KK; Janssen, WE; Moscinski, LC; Perkins, JB; Trudeau, WL, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (37.93) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 8 (27.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Terwisscha van Scheltinga, CE | 1 |
| Spronk, P | 1 |
| van Rosmalen, J | 1 |
| Wijnen, MH | 1 |
| Heij, HA | 1 |
| van Baren, R | 1 |
| Merks, JH | 1 |
| van Noesel, MM | 1 |
| Wijnen, RM | 1 |
| Lee, M | 1 |
| Kim, SW | 1 |
| Nam, EJ | 1 |
| Cho, H | 1 |
| Kim, JH | 1 |
| Kim, YT | 1 |
| Kim, S | 1 |
| Deroussent, A | 3 |
| Skarbek, C | 1 |
| Maury, A | 1 |
| Chapuis, H | 1 |
| Daudigeos-Dubus, E | 1 |
| Le Dret, L | 1 |
| Durand, S | 1 |
| Couvreur, P | 1 |
| Desmaële, D | 2 |
| Paci, A | 3 |
| Kesik, V | 1 |
| Demirkaya, E | 1 |
| Buyukpamukçu, M | 1 |
| Hamada, K | 1 |
| Tomita, Y | 1 |
| Inoue, A | 1 |
| Fujimoto, T | 1 |
| Hashimoto, N | 1 |
| Myoui, A | 1 |
| Yoshikawa, H | 1 |
| Hatazawa, J | 1 |
| Benz, MR | 1 |
| Czernin, J | 1 |
| Allen-Auerbach, MS | 1 |
| Tap, WD | 1 |
| Dry, SM | 1 |
| Elashoff, D | 1 |
| Chow, K | 1 |
| Evilevitch, V | 1 |
| Eckardt, JJ | 1 |
| Phelps, ME | 1 |
| Weber, WA | 1 |
| Eilber, FC | 1 |
| Rodriguez, S | 1 |
| Martelli, S | 1 |
| Seck, A | 1 |
| Dubus-Daudigeos, E | 1 |
| Vassal, G | 2 |
| Römpp, A | 1 |
| Guenther, S | 1 |
| Takats, Z | 1 |
| Spengler, B | 1 |
| Llewellyn, N | 1 |
| Lloyd, P | 1 |
| Jürgens, MD | 1 |
| Johnson, AC | 1 |
| Sala, P | 1 |
| Marchiolè, P | 1 |
| Cittadini, G | 1 |
| Valenzano Menada, M | 1 |
| Moioli, M | 1 |
| Mammoliti, S | 1 |
| Costantini, S | 1 |
| Billingham, LJ | 1 |
| Bathers, S | 1 |
| Burton, A | 1 |
| Bryan, S | 1 |
| Cullen, MH | 1 |
| Turci, R | 1 |
| Sottani, C | 2 |
| Ronchi, A | 1 |
| Minoia, C | 2 |
| Storme, T | 1 |
| Mercier, L | 1 |
| Re, M | 1 |
| Martens, T | 1 |
| Royer, J | 1 |
| Bourget, P | 1 |
| Tranfo, G | 1 |
| Faranda, P | 1 |
| Oliveira, RV | 1 |
| Onorato, JM | 1 |
| Siluk, D | 1 |
| Walko, CM | 1 |
| Lindley, C | 1 |
| Wainer, IW | 2 |
| Kasper, B | 1 |
| Dietrich, S | 1 |
| Dimitrakopoulou-Strauss, A | 1 |
| Strauss, LG | 1 |
| Haberkorn, U | 1 |
| Ho, AD | 1 |
| Egerer, G | 1 |
| Cortes, JE | 1 |
| Talpaz, M | 1 |
| Cabanillas, F | 1 |
| Seymour, JF | 1 |
| Kurzrock, R | 1 |
| Hattori, M | 1 |
| Tanaka, M | 1 |
| Yamazaki, Y | 1 |
| Nakahara, Y | 1 |
| Tsushita, K | 1 |
| Utumi, M | 1 |
| Anninga, JK | 1 |
| Valdés Olmos, RA | 1 |
| de Kraker, J | 3 |
| van Tinteren, H | 1 |
| Hoefnagel, CA | 1 |
| van Royen, EA | 1 |
| Corlett, SA | 1 |
| Chrystyn, H | 1 |
| Fields, KK | 1 |
| Elfenbein, GJ | 1 |
| Trudeau, WL | 1 |
| Perkins, JB | 1 |
| Janssen, WE | 1 |
| Moscinski, LC | 1 |
| Kaijser, GP | 1 |
| Ter Riet, PG | 1 |
| Bult, A | 1 |
| Beijnen, JH | 3 |
| Underberg, WJ | 1 |
| Kerbusch, T | 2 |
| Huitema, AD | 2 |
| Kettenes-van den Bosch, JJ | 1 |
| Keizer, HJ | 1 |
| Ouwerkerk, J | 1 |
| Zolezzi, C | 1 |
| Ferrari, S | 1 |
| Bacci, G | 1 |
| Fasano, MC | 1 |
| Sormani, G | 1 |
| Pizzoferrato, A | 1 |
| Sannolo, N | 1 |
| Miraglia, N | 1 |
| Biglietto, M | 1 |
| Acampora, A | 1 |
| Malorni, A | 1 |
| Thomson, B | 1 |
| Hawkins, D | 1 |
| Felgenhauer, J | 1 |
| Radich, J | 1 |
| Gourmel, B | 1 |
| Granvil, CP | 1 |
| Denis, SL | 1 |
| Bousquet, B | 1 |
| Jeuken, MJ | 1 |
| Derraz, J | 1 |
| van Putten, JW | 1 |
| Karle, P | 1 |
| Renner, M | 1 |
| Salmons, B | 1 |
| Günzburg, WH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Use of Ifosfamide, Doxorubicin and Hypofractionated Radiotherapy in Neoadjuvant Treatment of High-grade Extremity Soft Tissue and Non-metastatic Sarcomas[NCT02812654] | Phase 2 | 70 participants (Anticipated) | Interventional | 2015-03-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for ifosfamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Evaluation of chemotherapy response in osteosarcoma with FDG-PET.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone | 2009 |
Is magnetic resonance imaging useful in early evaluation of women on neoadjuvant chemotherapy for locally advanced cervical cancer?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; False Negative Reactions; Fe | 2012 |
Patterns, costs and cost-effectiveness of care in a trial of chemotherapy for advanced non-small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cos | 2002 |
Early prediction of therapy outcome in patients with high-risk soft tissue sarcoma using positron emission tomography.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Etoposide; Female; Fluorodeoxygl | 2008 |
25 other studies available for ifosfamide and Sensitivity and Specificity
| Article | Year |
|---|---|
Diagnosis and treatment of lymph node metastases in pediatric rhabdomyosarcoma in the Netherlands: a retrospective analysis.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brachytherapy; Child; Child, Pre | 2014 |
ATP-based chemotherapy response assay in primary or recurrent ovarian and peritoneal cancer.
Topics: Adenocarcinoma, Clear Cell; Adenosine Triphosphate; Adult; Aged; Antineoplastic Combined Chemotherap | 2014 |
Simultaneous quantification of preactivated ifosfamide derivatives and of 4-hydroxyifosfamide by high performance liquid chromatography-tandem mass spectrometry in mouse plasma and its application to a pharmacokinetic study.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Female; Ifosfamide; Linear Models; Mi | 2015 |
Urinary neutrophil gelatinase associated lipocalin as a biomarker in ifosfamide induced chronic renal failure.
Topics: Acute-Phase Proteins; Adolescent; Antineoplastic Agents, Alkylating; Biomarkers; Case-Control Studie | 2015 |
FDG-PET/CT imaging predicts histopathologic treatment responses after the initial cycle of neoadjuvant chemotherapy in high-grade soft-tissue sarcomas.
Topics: Adult; Aged; Aged, 80 and over; Deoxycytidine; Doxorubicin; Female; Fluorodeoxyglucose F18; Follow-U | 2009 |
Quantification of dimethyl-ifosfamide and its N-deschloropropylated metabolites in mouse plasma by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Chromatography, Liquid; Drug Stability; Female; Humans; Ifosfamide; Least-Squares Analysis; | 2011 |
Mass spectrometry imaging with high resolution in mass and space (HR(2) MSI) for reliable investigation of drug compound distributions on the cellular level.
Topics: Animals; Antineoplastic Agents; Benzamides; Diagnostic Imaging; Gastrointestinal Tract; Ifosfamide; | 2011 |
Determination of cyclophosphamide and ifosfamide in sewage effluent by stable isotope-dilution liquid chromatography-tandem mass spectrometry.
Topics: Antineoplastic Agents, Alkylating; Chromatography, Liquid; Cyclophosphamide; Ifosfamide; Magnesium S | 2011 |
Biological monitoring of hospital personnel occupationally exposed to antineoplastic agents.
Topics: Adult; Antineoplastic Agents, Alkylating; Chromatography, High Pressure Liquid; Cyclophosphamide; En | 2002 |
Liquid chromatography-mass spectrometry assay for quantitation of ifosfamide and its N-deschloroethylated metabolites in rat microsomal medium.
Topics: Animals; Antineoplastic Agents, Alkylating; Chromatography, High Pressure Liquid; Culture Media; Ifo | 2005 |
Highly sensitive high-performance liquid chromatography/selective reaction monitoring mass spectrometry method for the determination of cyclophosphamide and ifosfamide in urine of health care workers exposed to antineoplastic agents.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Cyclophosphamide; Humans; Ifosfamide; M | 2005 |
Enantioselective liquid chromatography-mass spectrometry assay for the determination of ifosfamide and identification of the N-dechloroethylated metabolites of ifosfamide in human plasma.
Topics: Chromatography, Liquid; Humans; Ifosfamide; Mass Spectrometry; Molecular Structure; Reference Standa | 2007 |
Serum levels of interleukin-10 in patients with diffuse large cell lymphoma: lack of correlation with prognosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Cisplatin | 1995 |
Detection of major and minor bcr/abl fusion gene transcripts in a patient with acute undifferentiated leukemia secondary to treatment with an alkylating agent.
Topics: Acute Disease; Alkylating Agents; Anemia, Sideroblastic; Base Sequence; Cell Transformation, Neoplas | 1995 |
Technetium-99m dimercaptosuccinic acid and ifosfamide tubular dysfunction in children with cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Dose-Response Relationship, | 1994 |
Enantiomeric separation of R- and S-ifosfamide and their determination in serum from clinical subjects.
Topics: Aged; Chromatography, High Pressure Liquid; Half-Life; Humans; Ifosfamide; Middle Aged; Sensitivity | 1994 |
Clinical significance of bone marrow metastases as detected using the polymerase chain reaction in patients with breast cancer undergoing high-dose chemotherapy and autologous bone marrow transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Bone Marrow Transplant | 1996 |
Determination of 4-hydroxyifosfamide in biological matrices by high-performance liquid chromatography.
Topics: Cerebellar Neoplasms; Child; Chromatography, High Pressure Liquid; Drug Stability; Humans; Ifosfamid | 1997 |
High-performance liquid chromatographic determination of stabilized 4-hydroxyifosfamide in human plasma and erythrocytes.
Topics: Acetonitriles; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Erythrocytes; Humans; | 1998 |
Determination of ifosfamide by HPLC using on-line sample preparation.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Chromatography, High Pressure Liquid; Humans; | 1999 |
Determination of cyclophosphamide and ifosphamide in urine at trace levels by gas chromatography/tandem mass spectrometry.
Topics: Cyclophosphamide; Gas Chromatography-Mass Spectrometry; Humans; Ifosfamide; Monitoring, Physiologic; | 1999 |
RT-PCR evaluation of peripheral blood, bone marrow and peripheral blood stem cells in children and adolescents undergoing VACIME chemotherapy for Ewing's sarcoma and alveolar rhabdomyosarcoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Purging; Bone N | 1999 |
Determination of 4-hydroxyifosfamide concomitantly with ifosfamide and its dechloroethylated metabolites using gas chromatography and a nitrogen phosphorus-selective detector.
Topics: Antineoplastic Agents, Alkylating; Chromatography, Gas; Humans; Ifosfamide; Mass Spectrometry; Repro | 1999 |
Determination of ifosfamide, 2- and 3-dechloroethyifosfamide using gas chromatography with nitrogen-phosphorus or mass spectrometry detection.
Topics: Antineoplastic Agents, Alkylating; Chromatography, Gas; Cyclophosphamide; Drug Monitoring; Gas Chrom | 2000 |
Necrotic, rather than apoptotic, cell death caused by cytochrome P450-activated ifosfamide.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Cats; Cell Line; Cells, Cultu | 2001 |