Page last updated: 2024-08-07 15:33:00

Trypsin

[no definition available]

Synonyms

EC 3.4.21.4

Research

Bioassay Publications (5)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Compounds (39)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
n-phenylmaleimideSus scrofa (pig)Ki800.000011
leupeptinSus scrofa (pig)IC500.350022
zpckSus scrofa (pig)IC50210.000011
tosylphenylalanyl chloromethyl ketoneSus scrofa (pig)IC50200.000011
arachidonic acidSus scrofa (pig)IC50200.000011
palmitoleic acidSus scrofa (pig)IC50200.000011
oleic acidSus scrofa (pig)IC50200.000011
eicosapentaenoic acidSus scrofa (pig)IC50200.000011
linoleic acidSus scrofa (pig)IC50200.000011
8,11,14-eicosatrienoic acidSus scrofa (pig)IC50200.000011
gamma-linolenic acidSus scrofa (pig)IC50200.000011
alpha-linolenic acidSus scrofa (pig)IC50200.000011
ginkgolic acidSus scrofa (pig)IC50200.000011
11,14,17-eicosatrienoateSus scrofa (pig)IC50200.000011
eicosa-11,14-dienoic acid, (z,z)-isomerSus scrofa (pig)IC50200.000011
a-317567Sus scrofa (pig)Ki0.090011

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
ofloxacinSus scrofa (pig)AC509.264010
amiloride hydrochloride, anhydrousSus scrofa (pig)AC509.298010
10-carboxymethyl-9-acridanoneSus scrofa (pig)AC507.069010
gamma-fagarineSus scrofa (pig)AC509.778010
2-[[5-[4-(1-piperidinylsulfonyl)phenyl]-1H-1,2,4-triazol-3-yl]thio]-N-(2-thiazolyl)acetamideSus scrofa (pig)AC5021.340010
2-(2,5-dimethoxyphenyl)-5-[4-(4-methoxyphenyl)phenyl]-1,3,4-oxadiazoleSus scrofa (pig)AC5010.380010
8-methoxy-5-methyl-3-[2-(1-pyrrolidinyl)ethyl]-4-pyrimido[5,4-b]indoloneSus scrofa (pig)AC5019.700010
5-phenyl-1,3,4-oxadiazole-2-thiolSus scrofa (pig)AC5013.290010
2-[[(4-phenyl-1,2,4-triazol-3-yl)thio]methyl]imidazo[1,2-a]pyrimidineSus scrofa (pig)AC509.655010
2-methyl-N-(1-methyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)propanamideSus scrofa (pig)AC5012.840010
2-(3-cyano-4,5,6-trimethyl-1H-pyridin-2-ylidene)propanedinitrileSus scrofa (pig)AC5012.090010
N-[[6-cyano-5-(ethylamino)-3-methyl-2-pyrazinyl]methyl]-N-phenylacetamideSus scrofa (pig)AC505.264010
2-[[anilino(oxo)methyl]amino]-4,5-dimethoxybenzoic acidSus scrofa (pig)AC503.340010
8-(9-methyl-5H-pyrimido[5,4-b]indol-4-yl)-1,4-dioxa-8-azaspiro[4.5]decaneSus scrofa (pig)AC5036.450010
N-(5-bromo-6-methyl-2-pyridinyl)-3-(2-oxo-1-benzopyran-3-yl)benzamideSus scrofa (pig)AC5016.630010
4-butyl-3-(3-methyl-2-thiophenyl)-1H-1,2,4-triazole-5-thioneSus scrofa (pig)AC509.998010
4-(benzenesulfonamido)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzamideSus scrofa (pig)AC5045.060010
5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-amineSus scrofa (pig)AC5010.690010
4-(3-hydroxyphenyl)-1-(2-oxolanylmethyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterSus scrofa (pig)AC509.882010
2-[(5,7-dimethyl-2-imidazo[1,2-a]pyrimidinyl)methylthio]acetic acidSus scrofa (pig)AC5012.040010
2-(2-furanylmethylamino)benzoic acid [2-[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-2-oxoethyl] esterSus scrofa (pig)AC509.066010
4-[3-[(3-chloro-4-fluoroanilino)-oxomethyl]-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]-1-piperidinecarboxylic acid tert-butyl esterSus scrofa (pig)AC5077.220010
(1S)-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-2-oxido-3,4-dihydro-1H-isoquinolin-2-ium-7-olSus scrofa (pig)AC5013.870010