Page last updated: 2024-12-10

1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

The compound you described, **1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene**, is not a well-known or widely studied compound. There is no readily available information on its specific properties, synthesis, or applications in research.

It is possible that the compound is:

* **A novel compound**: It could have been synthesized in a specific research project, but not yet published or widely characterized.
* **A misnomer**: There might be a typo in the name, and it actually refers to a different, known compound.
* **Not a real compound**: The structure might not be chemically feasible.

**To find out more about this compound, you would need:**

* **The context in which it was mentioned**: Where did you encounter this compound name? This context might give clues about its purpose.
* **Additional information**: Do you know any details about its properties, synthesis, or potential applications?
* **Consult a chemist or researcher**: A specialist in organic chemistry or a relevant research field might be able to provide further insight.

Without more information, it's difficult to assess its importance for research.

1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3033896
CHEMBL ID51887
CHEBI ID189901
MeSH IDM0239821

Synonyms (31)

Synonym
CHEMBL51887
68684-63-9
4-[(1e)-1,2-diphenylbut-1-en-1-yl]phenol
CHEBI:189901
4-[(e)-1,2-diphenylbut-1-enyl]phenol
tamoxifen metabolite e
ec 614-707-2
1-hpdpb
ici 77949
4-(1,2-diphenyl-1-butenyl)phenol
1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene
1-(4-hydroxyphenyl)-1,2-diphenylbut-1-ene
1,2-diphenyl-1-(4-hydroxyphenyl)but-1-ene
4-((e)-1,2-diphenylbut-1-enyl)phenol
phenol, 4-(1,2-diphenyl-1-butenyl)-
SL35001200 ,
(e,z)-1,2-diphenyl-1-(4-hydroxyphenyl)-but-1-ene
phenol, 4-(1,2-diphenyl-1-butenyl)-, (e,z)-
niosh/sl3500120
(e,z)-4-(1,2-diphenyl-1-butenyl)phenol
4-(1,2-diphenylbut-1-en-1-yl)phenol
AKOS037652173
4-(1,2-diphenyl-1-buten-1-yl)phenol
phenol, 4-(1,2-diphenyl-1-buten-1-yl)-
A9V8JZM9A9
(e)-1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene
(e,z)-4-(1,2-diphenylbut-1-en-1-yl)phenol
69967-79-9
(e)-4-(1,2-diphenyl-1-butenyl)phenol
4-[(1e)-1,2-diphenyl-1-buten-1-yl]phenol
phenol, 4-[(1e)-1,2-diphenyl-1-buten-1-yl]-
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
stilbenoidAny olefinic compound characterised by a 1,2-diphenylethylene backbone.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID102278Effect on the MCF-7 cell growth at 10e-6 M1987Journal of medicinal chemistry, Oct, Volume: 30, Issue:10
Synthesis, conformational considerations, and estrogen receptor binding of diastereoisomers and enantiomers of 1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylbutane (dihydrotamoxifen).
AID71135Relative binding affinity for estrogen receptor of calf uterine cytosol1987Journal of medicinal chemistry, Oct, Volume: 30, Issue:10
Synthesis, conformational considerations, and estrogen receptor binding of diastereoisomers and enantiomers of 1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylbutane (dihydrotamoxifen).
AID69076Relative binding affinity for estrogen receptor of MCF-7 cells1987Journal of medicinal chemistry, Oct, Volume: 30, Issue:10
Synthesis, conformational considerations, and estrogen receptor binding of diastereoisomers and enantiomers of 1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylbutane (dihydrotamoxifen).
AID102280Effect on the MCF-7 cell proliferation at 10e-8 M1987Journal of medicinal chemistry, Oct, Volume: 30, Issue:10
Synthesis, conformational considerations, and estrogen receptor binding of diastereoisomers and enantiomers of 1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylbutane (dihydrotamoxifen).
AID102279Effect on the MCF-7 cell proliferation at 10e-7 M1987Journal of medicinal chemistry, Oct, Volume: 30, Issue:10
Synthesis, conformational considerations, and estrogen receptor binding of diastereoisomers and enantiomers of 1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylbutane (dihydrotamoxifen).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.85

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.85 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.85)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]