Proteins > Neuronal acetylcholine receptor subunit alpha-10
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Neuronal acetylcholine receptor subunit alpha-10
A neuronal acetylcholine receptor subunit alpha-10 that is encoded in the genome of rat. [OMA:Q9JLB5, PRO:DNx]
Synonyms
Nicotinic acetylcholine receptor subunit alpha-10;
NACHR alpha-10
Research
Bioassay Publications (12)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (19)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| epibatidine | Rattus norvegicus (Norway rat) | K app | 0.0000 | 1 | 3 |
| nicotine | Rattus norvegicus (Norway rat) | K app | 0.0062 | 1 | 3 |
Absolute Configuration and Pharmacology of the Poison Frog Alkaloid Phantasmidine.Journal of natural products, , 04-27, Volume: 81, Issue:4, 2018
Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.Bioorganic & medicinal chemistry letters, , Apr-19, Volume: 14, Issue:8, 2004
Neuronal nicotinic acetylcholine receptors as targets for drug discovery.Journal of medicinal chemistry, , Dec-19, Volume: 40, Issue:26, 1997
Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: a new positron emission tomography ligand for nicotinic receptors.Journal of medicinal chemistry, , Jul-18, Volume: 40, Issue:15, 1997
Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.Journal of medicinal chemistry, , Feb-16, Volume: 39, Issue:4, 1996
Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.Bioorganic & medicinal chemistry letters, , Apr-19, Volume: 14, Issue:8, 2004
Neuronal nicotinic acetylcholine receptors as targets for drug discovery.Journal of medicinal chemistry, , Dec-19, Volume: 40, Issue:26, 1997
Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.Bioorganic & medicinal chemistry letters, , Apr-19, Volume: 14, Issue:8, 2004
Neuronal nicotinic acetylcholine receptors as targets for drug discovery.Journal of medicinal chemistry, , Dec-19, Volume: 40, Issue:26, 1997
Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: a new positron emission tomography ligand for nicotinic receptors.Journal of medicinal chemistry, , Jul-18, Volume: 40, Issue:15, 1997
Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.Journal of medicinal chemistry, , Feb-16, Volume: 39, Issue:4, 1996
(S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors.Journal of medicinal chemistry, , Aug-16, Volume: 39, Issue:17, 1996
Synthesis and evaluation of nicotine analogs as neuronal nicotinic acetylcholine receptor ligands.Journal of medicinal chemistry, , Oct-14, Volume: 37, Issue:21, 1994
Synthesis and biological characterization of pyridohomotropanes. Structure-activity relationships of conformationally restricted nicotinoids.Journal of medicinal chemistry, , Volume: 31, Issue:3, 1988
Structure-activity relationships of some pyridine, piperidine, and pyrrolidine analogues for enhancing and inhibiting the binding of (+/-)-[3H]nicotine to the rat brain P2 preparation.Journal of medicinal chemistry, , Volume: 28, Issue:9, 1985
Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.Bioorganic & medicinal chemistry letters, , Apr-19, Volume: 14, Issue:8, 2004
Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.Journal of medicinal chemistry, , Feb-16, Volume: 39, Issue:4, 1996