thorium X: used in therapy of Bechterew's disease [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 6328538 |
| CHEBI ID | 80503 |
| MeSH ID | M0086002 |
| Synonym |
|---|
| radium-224 |
| 13233-32-4 |
| 224ra |
| radium, isotope of mass 224 |
| unii-5se5nog2nw |
| 5se5nog2nw , |
| thorium x |
| CHEBI:80503 |
| radium ra-224 |
| DTXSID50912341 |
Thorium X is an ionizing radiation treatment that was commonly used by dermatologists in the 1930 s to 1950 s to treat a variety of benign dermatoses and vascular lesions including port-wine stains.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Thorium X is an ionizing radiation treatment that was commonly used by dermatologists in the 1930 s to 1950 s to treat a variety of benign dermatoses and vascular lesions including port-wine stains. " | ( Thorium X treatment: multiple basal cell carcinomas within a port-wine stain. Cliff, S; Natkunarajah, J, 2009) | 3.24 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " These results highlight the potential benefit of alpha radiation-based radiotherapy in combination with chemotherapeutic drugs for anticancer treatment." | ( Interstitial wires releasing diffusing alpha emitters combined with chemotherapy improved local tumor control and survival in squamous cell carcinoma-bearing mice. Arazi, L; Cooks, T; Efrati, M; Keisari, Y; Kelson, I; Marshak, G; Schmidt, M, 2009) | 0.35 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 98 (75.38) | 18.7374 |
| 1990's | 4 (3.08) | 18.2507 |
| 2000's | 20 (15.38) | 29.6817 |
| 2010's | 3 (2.31) | 24.3611 |
| 2020's | 5 (3.85) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (29.83) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 4 (2.96%) | 6.00% |
| Case Studies | 7 (5.19%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 124 (91.85%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|---|---|---|---|---|
| dimercaprol Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.. dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury. | 1.93 | 1 | 0 | dithiol; primary alcohol | chelator |
| limestone Calcium Carbonate: Carbonic acid calcium salt (CaCO3). An odorless, tasteless powder or crystal that occurs in nature. It is used therapeutically as a phosphate buffer in hemodialysis patients and as a calcium supplement.. calcium carbonate : A calcium salt with formula CCaO3. | 2.63 | 2 | 0 | calcium salt; carbonate salt; inorganic calcium salt; one-carbon compound | antacid; fertilizer; food colouring; food firming agent |
| thorium dioxide Thorium Dioxide: Thorium oxide (ThO2). A radiographic contrast agent that was used in the early 1930s through about 1954. High rates of mortality have been linked to its use and it has been shown to cause liver cancer. | 3.48 | 2 | 0 | thorium molecular entity | |
| lutetium Lutetium: An element of the rare earth family of metals. It has the atomic symbol Lu, atomic number 71, and atomic weight 175. | 1.96 | 1 | 0 | d-block element atom; lanthanoid atom | |
| platinum Platinum: A heavy, soft, whitish metal, resembling tin, with atomic number 78, atomic weight 195.084, symbol Pt. It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny's time as alutiae. | 6.92 | 1 | 0 | elemental platinum; nickel group element atom; platinum group metal atom | |
| thorium Thorium: A radioactive element of the actinide series of metals. It has an atomic symbol Th, atomic number 90, and atomic weight 232.04. It is used as fuel in nuclear reactors to produce fissionable uranium isotopes. Because of its radioopacity, various thorium compounds are used to facilitate visualization in roentgenography. | 8.32 | 130 | 0 | actinoid atom; f-block element atom | |
| uranium Uranium: A radioactive element of the actinide series of metals. It has an atomic symbol U, atomic number 92, and atomic weight 238.03. U-235 is used as the fissionable fuel in nuclear weapons and as fuel in nuclear power reactors. | 3.1 | 1 | 0 | actinoid atom; f-block element atom; monoatomic uranium | |
| zirconium Zirconium: A rather rare metallic element with atomic number 40, atomic weight 91.224, and symbol Zr. | 1.96 | 1 | 0 | titanium group element atom | |
| radon Radon: A naturally radioactive element with atomic symbol Rn, and atomic number 86. It is a member of the noble gas family found in soil, and is released during the decay of RADIUM.. radon(0) : A monoatomic radon that has an oxidation state of zero. | 7.38 | 2 | 0 | monoatomic radon; noble gas atom; p-block element atom | |
| radon-220 atom [no description available] | 2.25 | 1 | 0 | radon atom | |
| lead Lead: A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb. | 1.96 | 1 | 0 | carbon group element atom; elemental lead; metal atom | neurotoxin |
| bismuth Bismuth: A metallic element that has the atomic symbol Bi, and atomic number 83. Its principal isotope is Bismuth 209. | 2.42 | 2 | 0 | metal atom; pnictogen | |
| phosphorus Phosphorus: A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions. | 7.34 | 2 | 0 | monoatomic phosphorus; nonmetal atom; pnictogen | macronutrient |
| polonium Polonium: A radioactive element that is a member of the chalcogen family. It has the atomic symbol Po, atomic number 84, and the atomic weight of the isotope with the longest half-life (209Po) is 208.98. It decays by alpha-emission.. polonium atom : A radioactive metallic element discovered in 1898 by Marie Sklodowska Curie and named after her home country, Poland (Latin Polonia). | 1.96 | 1 | 0 | chalcogen; metal atom | |
| radium Radium: A radioactive element of the alkaline earth series of metals. It has the atomic symbol Ra and atomic number 88. Radium is the product of the disintegration of URANIUM and is present in pitchblende and all ores containing uranium. It is used clinically as a source of beta and gamma-rays in radiotherapy, particularly BRACHYTHERAPY. | 8.32 | 130 | 0 | alkaline earth metal atom | |
| lead radioisotopes Lead Radioisotopes: Unstable isotopes of lead that decay or disintegrate emitting radiation. Pb atoms with atomic weights 194-203, 205, and 209-214 are radioactive lead isotopes. | 2.83 | 3 | 0 | ||
| hyaluronoglucosaminidase Hyaluronoglucosaminidase: An enzyme that catalyzes the random hydrolysis of 1,4-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate. (From Enzyme Nomenclature, 1992) There has been use as ANTINEOPLASTIC AGENTS to limit NEOPLASM METASTASIS. | 1.93 | 1 | 0 | ||
| phosphorus radioisotopes Phosphorus Radioisotopes: Unstable isotopes of phosphorus that decay or disintegrate emitting radiation. P atoms with atomic weights 28-34 except 31 are radioactive phosphorus isotopes. | 1.93 | 1 | 0 |
| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|---|---|---|---|
| Carcinoma, Epidermoid [description not available] | 0 | 2.51 | 2 | 0 |
| Cancer of Head [description not available] | 0 | 2.81 | 3 | 0 |
| Cancer of Skin [description not available] | 0 | 3.56 | 9 | 0 |
| Pain, Procedural Pain associated with examination, treatment or procedures. | 0 | 2.25 | 1 | 0 |
| Local Neoplasm Recurrence [description not available] | 0 | 2.25 | 1 | 0 |
| Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 2.51 | 2 | 0 |
| Erythema Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes. | 0 | 7.37 | 2 | 0 |
| Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) | 0 | 2.81 | 3 | 0 |
| Skin Neoplasms Tumors or cancer of the SKIN. | 0 | 3.56 | 9 | 0 |
| Skin Ulcer An ULCER of the skin and underlying tissues. | 0 | 2.25 | 1 | 0 |
| Carcinoma, Squamous Cell of Head and Neck [description not available] | 0 | 2.25 | 1 | 0 |
| Squamous Cell Carcinoma of Head and Neck The most common type of head and neck carcinoma that originates from cells on the surface of the NASAL CAVITY; MOUTH; PARANASAL SINUSES, SALIVARY GLANDS, and LARYNX. Mutations in TNFRSF10B, PTEN, and ING1 genes are associated with this cancer. | 0 | 2.25 | 1 | 0 |
| Leucocythaemia [description not available] | 0 | 3.2 | 6 | 0 |
| Cancer, Radiation-Induced [description not available] | 0 | 5.57 | 17 | 0 |
| Ankylosing Spondylarthritis [description not available] | 0 | 6.3 | 27 | 0 |
| Leukemia A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 3.2 | 6 | 0 |
| Spondylitis, Ankylosing A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions. | 0 | 6.3 | 27 | 0 |
| Bone Cancer [description not available] | 0 | 3.68 | 10 | 0 |
| Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2.25 | 1 | 0 |
| Cancer of Prostate [description not available] | 0 | 2.53 | 2 | 0 |
| Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES. | 0 | 3.68 | 10 | 0 |
| Prostatic Neoplasms Tumors or cancer of the PROSTATE. | 0 | 2.53 | 2 | 0 |
| Cancer of Ovary [description not available] | 0 | 2.31 | 1 | 0 |
| Ovarian Neoplasms Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 0 | 2.31 | 1 | 0 |
| Alopecia Cicatrisata [description not available] | 0 | 2.62 | 3 | 0 |
| Alopecia Circumscripta [description not available] | 0 | 2.85 | 4 | 0 |
| Alopecia Absence of hair from areas where it is normally present. | 0 | 7.62 | 3 | 0 |
| Alopecia Areata Loss of scalp and body hair involving microscopically inflammatory patchy areas. | 0 | 7.85 | 4 | 0 |
| Nevus Flammeus [description not available] | 0 | 2.66 | 3 | 0 |
| Carcinoma, Basal Cell, Pigmented [description not available] | 0 | 3.21 | 6 | 0 |
| Facial Neoplasms New abnormal growth of tissue in the FACE. | 0 | 2.66 | 3 | 0 |
| Carcinoma, Basal Cell A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471) | 0 | 3.21 | 6 | 0 |
| Port-Wine Stain A vascular malformation of developmental origin characterized pathologically by ectasia of superficial dermal capillaries, and clinically by persistent macular erythema. In the past, port wine stains have frequently been termed capillary hemangiomas, which they are not; unfortunately this confusing practice persists: HEMANGIOMA, CAPILLARY is neoplastic, a port-wine stain is non-neoplastic. Port-wine stains vary in color from fairly pale pink to deep red or purple and in size from a few millimeters to many centimeters in diameter. The face is the most frequently affected site and they are most often unilateral. (From Rook et al., Textbook of Dermatology, 5th ed, p483) | 0 | 7.66 | 3 | 0 |
| Cancer of Lung [description not available] | 0 | 2.45 | 2 | 0 |
| Lung Neoplasms Tumors or cancer of the LUNG. | 0 | 2.45 | 2 | 0 |
| Female Genital Neoplasms [description not available] | 0 | 2.37 | 2 | 0 |
| Cancer of Kidney [description not available] | 0 | 2.05 | 1 | 0 |
| Granulocytic Leukemia [description not available] | 0 | 2.45 | 2 | 0 |
| Cancer of the Thyroid [description not available] | 0 | 2.05 | 1 | 0 |
| Genital Neoplasms, Female Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE). | 0 | 2.37 | 2 | 0 |
| Kidney Neoplasms Tumors or cancers of the KIDNEY. | 0 | 2.05 | 1 | 0 |
| Leukemia, Myeloid Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites. | 0 | 2.45 | 2 | 0 |
| Thyroid Neoplasms Tumors or cancer of the THYROID GLAND. | 0 | 2.05 | 1 | 0 |
| Fungal Diseases [description not available] | 0 | 1.92 | 1 | 0 |
| Mycoses Diseases caused by FUNGI. | 0 | 1.92 | 1 | 0 |
| Mycosis Fungoides A chronic, malignant T-cell lymphoma of the skin. In the late stages, the LYMPH NODES and viscera are affected. | 0 | 2.33 | 2 | 0 |
| Mole, Skin [description not available] | 0 | 2.62 | 3 | 0 |
| Feuerstein-Mims Syndrome [description not available] | 0 | 1.92 | 1 | 0 |
| Cancer of Colon [description not available] | 0 | 2.07 | 1 | 0 |
| Astrocytoma, Grade IV [description not available] | 0 | 2.07 | 1 | 0 |
| Malignant Melanoma [description not available] | 0 | 2.07 | 1 | 0 |
| Benign Neoplasms [description not available] | 0 | 3.33 | 7 | 0 |
| Colonic Neoplasms Tumors or cancer of the COLON. | 0 | 2.07 | 1 | 0 |
| Glioblastoma A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 2.07 | 1 | 0 |
| Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) | 0 | 2.07 | 1 | 0 |
| Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 3.33 | 7 | 0 |
| Injuries, Radiation [description not available] | 0 | 4.74 | 12 | 0 |
| Bone Tuberculosis [description not available] | 0 | 3.8 | 4 | 0 |
| Leukemia, Radiation-Induced Leukemia produced by exposure to IONIZING RADIATION or NON-IONIZING RADIATION. | 0 | 3.99 | 5 | 0 |
| Rheumatoid Arthritis [description not available] | 0 | 2.36 | 2 | 0 |
| Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. | 0 | 2.36 | 2 | 0 |
| Dermatoses [description not available] | 0 | 3.8 | 12 | 0 |
| Skin Diseases Diseases involving the DERMIS or EPIDERMIS. | 0 | 3.8 | 12 | 0 |
| Koch's Disease [description not available] | 0 | 3.04 | 5 | 0 |
| Tuberculosis Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS. | 0 | 3.04 | 5 | 0 |
| Ankylosis Fixation and immobility of a joint. | 0 | 3.03 | 5 | 0 |
| Spondylitis Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions. | 0 | 3.54 | 9 | 0 |
| Hair Diseases Diseases affecting the orderly growth and persistence of hair. | 0 | 1.93 | 1 | 0 |
| Nevi, Melanocytic [description not available] | 0 | 2.62 | 3 | 0 |
| Nevus, Pigmented A nevus containing melanin. The term is usually restricted to nevocytic nevi (round or oval collections of melanin-containing nevus cells occurring at the dermoepidermal junction of the skin or in the dermis proper) or moles, but may be applied to other pigmented nevi. | 0 | 2.62 | 3 | 0 |
| Chronic Illness [description not available] | 0 | 1.93 | 1 | 0 |
| Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 1.93 | 1 | 0 |
| Dermatitis Any inflammation of the skin. | 0 | 2.33 | 2 | 0 |
| Cervical Tuberculous Lymphadenitis [description not available] | 0 | 1.93 | 1 | 0 |
| Breast Diseases Pathological processes of the BREAST. | 0 | 1.93 | 1 | 0 |
| Angioma A vascular anomaly due to proliferation of blood or lymphatic vessels that forms a tumor-like mass. Vessels in the angioma may or may not be dilated. | 0 | 3.04 | 5 | 0 |
| Atrophy Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. | 0 | 6.93 | 1 | 0 |
| Hemangioma A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000) | 0 | 3.04 | 5 | 0 |
| Leukemia, Plasmacytic [description not available] | 0 | 2.84 | 4 | 0 |
| Leukemia, Plasma Cell A rare, aggressive variant of MULTIPLE MYELOMA characterized by the circulation of excessive PLASMA CELLS in the peripheral blood. It can be a primary manifestation of multiple myeloma or develop as a terminal complication during the disease. | 0 | 2.84 | 4 | 0 |
| Breast Cancer [description not available] | 0 | 1.93 | 1 | 0 |
| Breast Neoplasms Tumors or cancer of the human BREAST. | 0 | 1.93 | 1 | 0 |
| Verruca [description not available] | 0 | 1.93 | 1 | 0 |
| Warts Benign epidermal proliferations or tumors; some are viral in origin. | 0 | 1.93 | 1 | 0 |
| Behavior Disorders [description not available] | 0 | 1.93 | 1 | 0 |
| Psychoses, Drug [description not available] | 0 | 1.93 | 1 | 0 |
| Psychoses [description not available] | 0 | 1.93 | 1 | 0 |
| Mental Disorders Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function. | 0 | 1.93 | 1 | 0 |
| Psychotic Disorders Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994) | 0 | 1.93 | 1 | 0 |
| Sarcoma, Epithelioid [description not available] | 0 | 3.06 | 5 | 0 |
| Osteogenic Sarcoma [description not available] | 0 | 2.37 | 2 | 0 |
| Sarcoma A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant. | 0 | 3.06 | 5 | 0 |
| Osteosarcoma A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed) | 0 | 2.37 | 2 | 0 |
| Carcinoma, Anaplastic [description not available] | 0 | 2.33 | 2 | 0 |
| Carcinoma, Ehrlich Tumor A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. | 0 | 1.93 | 1 | 0 |
| Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 2.33 | 2 | 0 |
| Leukocytopenia [description not available] | 0 | 1.93 | 1 | 0 |
| Leukopenia A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000). | 0 | 1.93 | 1 | 0 |
| Dermatomycoses Superficial infections of the skin or its appendages by any of various fungi. | 0 | 1.93 | 1 | 0 |
| Agnogenic Myeloid Metaplasia [description not available] | 0 | 1.93 | 1 | 0 |
| Bone Marrow Diseases Diseases involving the BONE MARROW. | 0 | 1.93 | 1 | 0 |
| Primary Myelofibrosis A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone. | 0 | 1.93 | 1 | 0 |
| Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 2.41 | 2 | 0 |
| Keratoderma Blennorrhagicum [description not available] | 0 | 1.92 | 1 | 0 |
| Keratosis Any horny growth such as a wart or callus. | 0 | 1.92 | 1 | 0 |
| Bannayan-Riley-Ruvalcaba Syndrome [description not available] | 0 | 1.93 | 1 | 0 |
| Hamartoma Syndrome, Multiple A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE. | 0 | 1.93 | 1 | 0 |
| Polyarthritis [description not available] | 0 | 1.93 | 1 | 0 |
| Arthritis Acute or chronic inflammation of JOINTS. | 0 | 1.93 | 1 | 0 |
| Arthritis, Spinal [description not available] | 0 | 1.93 | 1 | 0 |
| Chemical Dependence [description not available] | 0 | 1.93 | 1 | 0 |
| Substance-Related Disorders Disorders related to substance use or abuse. | 0 | 1.93 | 1 | 0 |
| Dermatosclerosis [description not available] | 0 | 1.92 | 1 | 0 |
| Sclerosis, Systemic [description not available] | 0 | 1.92 | 1 | 0 |
| Scleroderma, Localized A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules. | 0 | 1.92 | 1 | 0 |
| Scleroderma, Systemic A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. | 0 | 1.92 | 1 | 0 |
| Bleb [description not available] | 0 | 2.03 | 1 | 0 |
| Stunted Growth [description not available] | 0 | 2.39 | 2 | 0 |
| Chondrosteoma [description not available] | 0 | 2.03 | 1 | 0 |
| Growth Disorders Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth. | 0 | 2.39 | 2 | 0 |
| Acute Myelogenous Leukemia [description not available] | 0 | 2.04 | 1 | 0 |
| Leukemia, Myeloid, Acute Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES. | 0 | 2.04 | 1 | 0 |
| Bone Loss, Osteoclastic [description not available] | 0 | 1.96 | 1 | 0 |
| Tooth Fractures Break or rupture of a tooth or tooth root. | 0 | 2.37 | 2 | 0 |
| Tooth Resorption Resorption of calcified dental tissue, involving demineralization due to reversal of the cation exchange and lacunar resorption by osteoclasts. There are two types: external (as a result of tooth pathology) and internal (apparently initiated by a peculiar inflammatory hyperplasia of the pulp). (From Jablonski, Dictionary of Dentistry, 1992, p676) | 0 | 1.96 | 1 | 0 |
| Chloasma [description not available] | 0 | 1.96 | 1 | 0 |
| Melanosis Disorders of increased melanin pigmentation that develop without preceding inflammatory disease. | 0 | 1.96 | 1 | 0 |
| Cancer, Second Primary [description not available] | 0 | 1.98 | 1 | 0 |
| Hepatocellular Carcinoma [description not available] | 0 | 7.9 | 1 | 0 |
| Cancer of Liver [description not available] | 0 | 2.9 | 1 | 0 |
| Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 2.9 | 1 | 0 |
| Liver Neoplasms Tumors or cancer of the LIVER. | 0 | 2.9 | 1 | 0 |
| Germinoblastoma [description not available] | 0 | 2 | 1 | 0 |
| Chordoma A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed) | 0 | 2 | 1 | 0 |
| Lymphoma A general term for various neoplastic diseases of the lymphoid tissue. | 0 | 2 | 1 | 0 |
| Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 1.97 | 1 | 0 |
| Cataract, Membranous [description not available] | 0 | 2.37 | 2 | 0 |
| Cataract Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) | 0 | 2.37 | 2 | 0 |
| Experimental Radiation Injuries [description not available] | 0 | 2.37 | 2 | 0 |
| Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 1.96 | 1 | 0 |
| EHS Tumor [description not available] | 0 | 1.96 | 1 | 0 |